ライフサイエンスコーパス: epiboly

1 erative factors, including cyclin D1, at 70% epiboly.

2 during Wnt/PCP signalling without affecting epiboly.

3 ssion patterns and explains expansion during epiboly.

4 of morphogenetic movements during zebrafish epiboly.

5 l and temporal movements of BCR cells during epiboly.

6 rrest of development at the beginning of the epiboly.

7 edge of the presumptive neuroectoderm by 70% epiboly.

8 re required for blastocoel roof thinning and epiboly.

9 te in involution as the blastoderm undergoes epiboly.

10 nover within EVL cells during the process of epiboly.

11 r progenitors in the zebrafish embryo at 40% epiboly, a stage prior to the initiation of gastrulation

12 re normally expressed in the germring by 50% epiboly and are induced in the primordium of rhombomere

13 at the one-cell stage resulted in defects at epiboly and C&E.

14 These waves first appeared at about 65% epiboly and continued to arise every 5-10 min up to at l

15 ding or FN fibrillogenesis but perturbs both epiboly and convergence/extension.

16 has largely been interpreted to result from epiboly and convergent-extension movements that drive bo

17 ncluding the cell movements of gastrulation, epiboly and dorsal convergence.

18 fish B-ephrins are expressed as early as 30% epiboly and during gastrula stages: in the germ ring, sh

19 re-derived surface epithelium that undergoes epiboly and in the large vegetal blastomeres that gradua

20 e that Yes kinase plays an important role in epiboly and indicate that Yes kinase participates in sig

21 by deregulating the epithelial movements of epiboly and involution.

22 ession begins immediately after the onset of epiboly and is most active before appearance of the germ

23 embrane impermeant fluorescent probes to pre-epiboly and mid-epiboly embryos.

24 blastomeres to respond to signals directing epiboly and not on the signals themselves.

25 e embryos are smaller and exhibit defects in epiboly and patterning of axial and prechordal mesoderm.

26 nalling was established as being between 60% epiboly and tailbud stages using the Fgf receptor inhibi

27 towards the vegetal pole in the movements of epiboly and towards the dorsal midline in convergent mov

28 nt predictions of cell rearrangements during epiboly, and here was used to predict successfully the l

29 morpholino oligonucleotide caused defects in epiboly, and led to reduced cell adhesion as shown by ce

30 1 kinases reduces a specific cell migration, epiboly, and results in the reduction of goosecoid expre

31 lization, then increase progressively during epiboly, and was maintained at high levels throughout ga

32 ebrate morphogenesis, we have focused on the epiboly arrest mutant half baked (hab), which segregates

33 ing a putative dominant negative Irf6 caused epiboly arrest, loss of gene expression characteristic o

34 own results in impaired cell movement during epiboly as well as in subsequent stages.

35 al cells have been shown to rearrange during epiboly, as they spread to cover the large yolk cell.

36 as a thickening in the germ ring of the mid-epiboly blastoderm.

37 ptosis in morphants were normal prior to 90% epiboly, but were elevated after 10 h post-fertilization

38 s, affect the major morphogenetic processes, epiboly, convergence and extension, and tail morphogenes

39 lsr activity in zebrafish embryos results in epiboly defects that appear to be independent of the req

40 cohesion that primarily leads to the in vivo epiboly defects.

41 velopmental phenotypes, including a delay in epiboly, depleted S1P levels, elevated levels of sphingo

42 ailed to migrate toward the vegetal pole and epiboly did not occur, a phenotype similar but distinct

43 erienced by the rearranging EVL cells, post- epiboly embryos, whose EVL cells no longer rearrange, we

44 nt fluorescent probes to pre-epiboly and mid-epiboly embryos.

45 acquired regional identity as a group at 80% epiboly even before making vertical contact with axial m

46 the embryonic midline and the micromere cap, epiboly fails, and the HRO-NOS knockdown embryos die.

47 Apart from disrupting epiboly, FoxH1 MO treatment disrupts convergence and int

48 In situ analyses show that during late epiboly hab is expressed in a radial gradient in the non

49 In contrast, when transplanted at 80% epiboly, hindbrain cells retain their neural fate and ex

50 cs during morphogenetic processes that drive epiboly in early Danio rerio (zebrafish) development.

51 Here we describe cellular events during epiboly in normal embryos and in embryos perturbed by ei

52 studies indicate that Galpha(12/13) regulate epiboly, in part by associating with the cytoplasmic ter

53 l positions of myocardial progenitors at 40% epiboly indicate that signals residing at the embryonic

54 a YSL-driven zygotic mechanism essential for epiboly initiation and reveals a Ca(2+) channel-independ

55 deficient zebrafish embryos, impaired in the epiboly, internalization, convergence and extension gast

56 directional movements of cells that include epiboly, involution, and convergence and extension (C&E)

57 Epiboly is restored by coinjection of human beta4 cRNA o

58 l membrane turnover in the EVL cells of post-epiboly killifish embryos is accelerated at cell-cell co

59 hyperactivation and progress faster through epiboly, leading to tailbud-stage embryos that have a na

60 eting translation of foxH1 disrupt embryonic epiboly movements during gastrulation and cause death on

61 Epiboly movements expand and thin the nascent germ layer

62 ell layer, which are both known mediators of epiboly movements.

63 Beginning at stage 9, epiboly of the animal cap moves tissue into the dorsal b

64 The epiboly of the Caenorhabditis elegans hypodermis involve

65 the contractile actomyosin ring coordinates epiboly on both the organismal and cellular scales.

66 e that Fyn kinase plays an important role in epiboly, possibly through its effects in calcium signali

67 hrough oriented cell division and to promote epiboly, possibly through maintenance of tissue-surface

68 clude incomplete dorsal convergence, delayed epiboly progression and an early lysis phenotype during

69 We show that during the early stages of epiboly, spindles in the epithelium display dynamic beha

70 Epiboly spreads and thins the blastoderm over the yolk c

71 ar markers reveal that the axial mesoderm of epiboly stage embryos is abnormally widened in beta4GalT

72 gradient is established between 30% and 40% epiboly stages and that it is preceded by graded mRNA ex

73 e epithelial morphogenetic events, including epiboly, that also employ an underlying substrate.

74 On completion of epiboly, the dorsal locus was incorporated into the deve

75 zebrafish beta4 protein blocks initiation of epiboly, the first morphogenetic movement of teleost emb

76 At approximately 90% epiboly, the forerunner cell cluster becomes overlapped

77 as "forerunner cells." Between 60%- and 80%-epiboly, the forerunner cells coalesce into a coherent c

78 long-range intercellular coordination during epiboly, the process in which the blastoderm spreads ove

79 Epiboly, the spreading of the blastoderm over the large

80 Using amphibian epiboly, the thinning and spreading of the animal hemisp

81 ents of convergence and extension as well as epiboly through the G-protein-coupled PGE(2) receptor (E

82 in vivo evidence that Galpha(12/13) regulate epiboly through two distinct mechanisms: limiting E-cadh

83 During epiboly, using an asymmetric variant of radial intercala

84 over, this turnover rate is increased during epiboly, when the cells are actively rearranging.

85 ased deep cell adhesion and fail to initiate epiboly, which can be rescued by re-expression of 2-OST