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1 e occurred during the 2013-2016 West African epidemic.
2 ffective antibody-based vaccine to quell the epidemic.
3 needed if we are committed to ending the TB epidemic.
4 ies show variations of a shared hip fracture epidemic.
5 asonable explanation for the current obesity epidemic.
6 the effective prevention and control of the epidemic.
7 susceptible tuberculosis to a drug-resistant epidemic.
8 o the severity and scope of the 2013-16 EBOV epidemic.
9 able to the adverse consequences of the ZIKV epidemic.
10 c, while this may be different for the HCV4d epidemic.
11 omic sequences proved a monophyletic HAdV-D8 epidemic.
12 arise, but so rarely that it does not become epidemic.
13 populations are important to the broader HIV epidemic.
14 been implicated in the obesity and diabetes epidemic.
15 ined targets aimed at halting the global HIV epidemic.
16 intestinal microflora in the rising obesity epidemic.
17 o different outbreaks from the Swedish HIV-1 epidemic.
18 nt countries suggests variations of the same epidemic.
19 ers significantly contributed to China's HIV epidemic.
20 to confront the emerging drug-resistant HIV epidemic.
21 on and prediction using stochastic models of epidemics.
22 the 2016-17 epidemic compared with previous epidemics.
23 ccurred from January to April and in regular epidemics.
24 cy outcomes during Ebola virus disease (EVD) epidemics.
25 o the swine industry worldwide during recent epidemics.
26 ons and ultimately the magnitude of parasite epidemics.
27 ns to reconstruct transmission histories and epidemics.
28 to greatly reduced vaccine uptake and large epidemics.
29 y the global HIV and hepatitis C virus (HCV) epidemics.
30 epidemic was similar to that in the previous epidemics.
31 us identify the source of current and future epidemics.
32 will help to inform interventions in future epidemics.
33 ntial of widespread viral haemorrhagic fever epidemics.
34 ecology and evolution of infectious disease epidemics.
35 mics, including the 2014 Ebola and 2015 Zika epidemics.
36 , and had more confirmed cases than previous epidemics.
37 gens, particularly viruses that cause lethal epidemics.
38 y reduce transmission and aid the control of epidemics.
39 helping to investigate disease outbreaks and epidemics.
40 idity and mortality, with worldwide seasonal epidemics.
41 te for the analysis of future mosquito-borne epidemics.
42 to provide lasting protection from seasonal epidemics.
43 etter strategies for prevention of livestock epidemics.
44 d treatment might improve care in future EVD epidemics.
45 proved to be important for several livestock epidemics.
46 crucial priority for halting the HIV and HCV epidemics.
47 communication and resource allocation during epidemics.
48 facilitated transmission during recent ZIKV epidemics.
50 y) were higher than those in the first three epidemics (39% [52 of 134], 55% [169 of 306], and 56% [1
51 d rural residents in the 2015-16 and 2016-17 epidemics (63% [72 of 114] and 61% [274 of 447], respect
52 in areas with Zika virus (ZIKV) outbreaks or epidemics adopt prophylactic measures to reduce or elimi
53 quito-transmitted flavivirus that now causes epidemics affecting millions of people on multiple conti
54 The diagnostic response to the 2014-15 Ebola epidemic, although ultimately effective, was slow and ex
57 ed the recent Zika virus (ZIKV) infection an epidemic and a public health emergency of global concern
59 demic influenza A(H1N1) virus (A[H1N1]pdm09) epidemic and concurrent influenza B(Victoria) virus acti
61 ession are urgently needed to curtail the AF epidemic and improve outcomes in affected individuals.
62 care and prevention services to curb the HIV epidemic and improve the quality of life of transwomen i
63 e potential magnitude and timing of the ZIKV epidemic and it can be potentially used as a template fo
66 current landscape of the heart failure (HF) epidemic and provide targets for future health policy in
67 Epidemiological data from the 2002-2003 SARS epidemic and recent Middle East respiratory syndrome out
68 quired an A82V change during the West Africa epidemic and that this change altered the capacity of GP
69 tion (WHO), has committed to ending the AIDS epidemic and to ensuring that 90% of people living with
70 ort-term surveillance that focuses on single epidemics and acutely ill individuals, the subtle dynami
71 Influenza A viruses (IAVs) cause seasonal epidemics and occasional pandemics, representing a serio
75 help China change the trajectory of its HIV epidemic, and help to achieve the goal of an end to AIDS
77 are driving the ongoing global tuberculosis epidemic, and there is a pressing need for research focu
78 inia 1994 (VA1994), the index isolate of the epidemic, and Virginia 2013 (VA2013), a recent isolate o
79 d the epidemiological characteristics across epidemics, and estimated the risk of death, mechanical v
80 used to forecast invasive bacterial disease epidemics, and simple control measures to reduce particu
81 the evolutionary trajectories driving these epidemics are replicated using a simple cell-based exper
82 tein (GP) that occurred early in the 2013-16 epidemic, are suspected to confer a selective advantage
83 contributors to the growing sleep deficiency epidemic, as is the high prevalence of sleep disorders l
84 th severe congenital malformations, the ZIKV epidemic became an imperative for mobilization, renewed
86 he degree distribution is not independent of epidemics but is shaped through disease-induced dynamics
87 dominated among regions affected by the ZIKV epidemic, but the spectrum of neurological disease in th
88 lessen the multidrug-resistant tuberculosis epidemic, but this effect depends on its long-term effic
90 idium difficile infection through dysbiosis, epidemic C difficile ribotypes characterised by multidru
93 erinvasive meningococci, suggesting that the epidemic clones emerged by acquisition of pre-existing m
97 environmental patterns associated with these epidemics, comparing human and ruminant serological data
100 wed us to detect specific events, like wars, epidemics, coronations, or conclaves, with high accuracy
101 t begomoviruses characterized from the first epidemic; Cotton leaf curl Multan virus, Cotton leaf cur
102 trial conducted in Guinea during the recent epidemic demonstrated that a recombinant VSV where G pro
107 of chronic shedding relative to more obvious epidemic drivers, and poor ability to differentiate betw
118 nd adverse disease outcomes of the 2015-2016 epidemic have elevated ZIKV from a previously understudi
119 poradic clusters at the end of the 2013-2016 epidemic have prompted recommendations that male survivo
124 ise for sensitive point-of-care detection of epidemic human norovirus, and is the fastest human norov
125 rticularly the Syrian conflict and the Ebola epidemic, I recommend four sets of actions that would ma
126 ed research completed during the west Africa epidemic, identify ongoing knowledge gaps, and suggest p
130 ana played a pivotal role in the Chikungunya epidemic in Brazil and was one of the first urban centre
131 y extensive, most fatal, and longest lasting epidemic in Ebola's history, presented an enormous inter
132 ern Pacific, followed in 2013-14 by a larger epidemic in French Polynesia, south Pacific, where the f
133 threat to long-term control of the HIV-AIDS epidemic in low- and middle-income countries (LMICs).
134 lining epidemic overall but with a large sub-epidemic in MSM and male sex workers, an optimal prevent
137 an index case can escalate into a widespread epidemic in the absence of intervention (eg, Nigeria and
141 in-resistant Staphylococcus aureus (CA-MRSA) epidemic in the United States is largely attributable to
148 ynamic transmission model of multi-strain TB epidemics in hypothetical populations reflective of the
152 may be responsible for the initiation of CLS epidemics in mixed-cropping farms, whereas external sour
153 a has experienced two of the largest cholera epidemics in modern history; one in 1991 and the other i
161 rkov model to represent India's tuberculosis epidemic, including a probabilistic framework reflecting
162 ry year, which is comparable to recent acute epidemics, including the 2014 Ebola and 2015 Zika epidem
164 l status of marijuana, addressing the opioid epidemic, insurance coverage of substance use disorders
165 or, this disparity, to integrate concomitant epidemics into models, and to understand reasons for rac
167 t gammaretrovirus infections, yet no current epidemic is evident, despite environmental exposure to v
170 three time periods: pre-Ebola virus disease epidemic (January, 2013, to February, 2014), during-epid
171 surveillance system revealed an increase of epidemic keratoconjunctivitis (EKC) from an average of 3
175 tance, there is a strong bias for sequencing epidemic lineages of methicillin-resistant Staphylococcu
177 Herein, using a genetically representative epidemic M1 strain and a panel of isogenic mutant deriva
178 HIV transmission associated with the opioid epidemic make cost-effective programs for people who inj
179 hough the ZEBOV variant responsible for this epidemic (Makona) shares significant genetic similarity
180 c (January, 2013, to February, 2014), during-epidemic (March, 2014, to February, 2015) and post-epide
190 importance of measures to reduce the global epidemic of childhood obesity and encourage mechanistic
192 ct a gradual transformation from the current epidemic of drug-susceptible tuberculosis to a drug-resi
194 , and effective interventions to reverse the epidemic of obesity in women of childbearing age and to
196 drome is rarely diagnosed, given the current epidemic of opioid use, it is likely to be under-recogni
199 ng syndrome in Canada in the early 1990s, an epidemic of severe systemic disease due to PCV2 spread w
201 We jointly analysed datasets describing the epidemic of yellow fever, vector suitability, human demo
206 the most important viral pathogens, causing epidemics of acute respiratory infection (ARI), especial
207 ) is a mosquito-borne flavivirus that causes epidemics of encephalitis and viscerotropic disease worl
208 man genome sequence, which reveals many past epidemics of gammaretrovirus infection, and from recent
213 for the targeted control of dynamics such as epidemics, or for modifying biochemical pathways relatin
214 Early resolution of uncertainty during an epidemic outbreak can lead to rapid and efficient decisi
216 oradic outbreaks, the virus has caused major epidemic outbreaks in Africa, Asia, the Indian Ocean, an
220 of point-of-care diagnostics, quarantine of epidemic pathogens, and prevention of terrorism's bio-at
223 Winter holidays delay seasonal influenza epidemic peaks and shift disease risk toward adults beca
226 child vaccination completion during the pre-epidemic period was followed by significant immediate an
228 From November 2011 until December 2013 (epidemic period) 85% of typed isolates were human adenov
233 ith standardized protocols conducted outside epidemic periods would help to clarify the circumstances
235 s and could benefit from real-time influenza epidemic prediction web tools such as Google Flu Trends
236 aracterized, hindering refinements of future epidemic predictions and explorations of targeted interv
237 particularly crucial for enabling a general epidemic predictive framework at the individual level.
238 called by immunization.IMPORTANCE The dengue epidemic presents a global public health challenge that
240 d atrial fibrillation (AF) are increasing in epidemic proportions, and both increase the prevalence o
245 tive pressures favouring multidrug-resistant epidemic ribotypes and was associated with substantial d
246 in the incidence of suspected meningitis and epidemic risk, and a substantial effect on confirmed gro
247 nt implication in both genome plasticity and epidemic risk, but the early stages of the infection hav
252 that increased production of SPN and SLO in epidemic serotype M1 and M89 S. pyogenes strains is asso
253 d case sources have changed gradually across epidemics since 2013, while clinical severity has not ch
255 the susceptible-infective-recovered model of epidemic spread, which combines both agent-to-agent hete
261 logenetic analysis reveals that contemporary epidemic strains have accumulated multiple substitutions
264 ition to the K166Q mutation that occurred in epidemic strains, other HA mutations can confer resistan
265 ective sweep of specific var genes or clonal epidemic structure related to the incidence of uncomplic
267 spatial/demographic incidence of the obesity epidemic suggest that economic policies aimed at expandi
270 e series data collected during the 2009 H1N1 epidemic that includes information about vaccination, fl
271 are the causative agents of annual influenza epidemics that can be severe, and influenza A viruses in
273 ork that captured dynamics of the Zika virus epidemic, the risk of GBS in Zika virus-infected persons
275 a, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever v
276 The relative risk of districts reaching the epidemic threshold of ten per 100 000 per week was estim
279 hagic fever in humans and is responsible for epidemics throughout sub-Saharan, central, and West Afri
281 o-layered network model of coupled recurrent epidemics to reproduce the synchronized and mixed outbre
282 haracterized the changes to transmission and epidemic trajectories among children and adults in a spa
283 s provides a unified assessment of potential epidemic trajectories, with the aim of allowing national
284 orks and show that this process exhibits two epidemic transitions corresponding to a core-periphery s
285 s species of mosquitoes and is capable of an epidemic, urban transmission cycle with high rates of in
286 Our results indicate that the start of the epidemic was driven by horizontal dissemination of mobil
288 e acquired immune deficiency syndrome (AIDS) epidemic was first recognized in 1981, and it quickly be
289 ividuals admitted to hospital in the 2016-17 epidemic was similar to that in the previous epidemics.
290 cess.IMPORTANCE The West African Ebola virus epidemic was the largest to date, with more than 28,000
291 es of parasite interactions and phenology in epidemics, we embedded multiple cohorts of sentinel plan
294 try spread in shaping the Saudi Arabia HCV4a epidemic, while this may be different for the HCV4d epid
295 abuse and addiction have become a worldwide epidemic with great societal and financial burdens, high
299 in our framework), that consider the cost of epidemic years, and that account for productivity and to
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