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1 e occurred during the 2013-2016 West African epidemic.
2 ffective antibody-based vaccine to quell the epidemic.
3  needed if we are committed to ending the TB epidemic.
4 ies show variations of a shared hip fracture epidemic.
5 asonable explanation for the current obesity epidemic.
6  the effective prevention and control of the epidemic.
7 susceptible tuberculosis to a drug-resistant epidemic.
8 o the severity and scope of the 2013-16 EBOV epidemic.
9 able to the adverse consequences of the ZIKV epidemic.
10 c, while this may be different for the HCV4d epidemic.
11 omic sequences proved a monophyletic HAdV-D8 epidemic.
12 arise, but so rarely that it does not become epidemic.
13 populations are important to the broader HIV epidemic.
14  been implicated in the obesity and diabetes epidemic.
15 ined targets aimed at halting the global HIV epidemic.
16  intestinal microflora in the rising obesity epidemic.
17 o different outbreaks from the Swedish HIV-1 epidemic.
18 nt countries suggests variations of the same epidemic.
19 ers significantly contributed to China's HIV epidemic.
20  to confront the emerging drug-resistant HIV epidemic.
21 on and prediction using stochastic models of epidemics.
22  the 2016-17 epidemic compared with previous epidemics.
23 ccurred from January to April and in regular epidemics.
24 cy outcomes during Ebola virus disease (EVD) epidemics.
25 o the swine industry worldwide during recent epidemics.
26 ons and ultimately the magnitude of parasite epidemics.
27 ns to reconstruct transmission histories and epidemics.
28  to greatly reduced vaccine uptake and large epidemics.
29 y the global HIV and hepatitis C virus (HCV) epidemics.
30 epidemic was similar to that in the previous epidemics.
31 us identify the source of current and future epidemics.
32  will help to inform interventions in future epidemics.
33 ntial of widespread viral haemorrhagic fever epidemics.
34  ecology and evolution of infectious disease epidemics.
35 mics, including the 2014 Ebola and 2015 Zika epidemics.
36 , and had more confirmed cases than previous epidemics.
37 gens, particularly viruses that cause lethal epidemics.
38 y reduce transmission and aid the control of epidemics.
39 helping to investigate disease outbreaks and epidemics.
40 idity and mortality, with worldwide seasonal epidemics.
41 te for the analysis of future mosquito-borne epidemics.
42  to provide lasting protection from seasonal epidemics.
43 etter strategies for prevention of livestock epidemics.
44 d treatment might improve care in future EVD epidemics.
45 proved to be important for several livestock epidemics.
46 crucial priority for halting the HIV and HCV epidemics.
47 communication and resource allocation during epidemics.
48  facilitated transmission during recent ZIKV epidemics.
49 eturned responders to the West African Ebola epidemic 2014-2016.
50 y) were higher than those in the first three epidemics (39% [52 of 134], 55% [169 of 306], and 56% [1
51 d rural residents in the 2015-16 and 2016-17 epidemics (63% [72 of 114] and 61% [274 of 447], respect
52 in areas with Zika virus (ZIKV) outbreaks or epidemics adopt prophylactic measures to reduce or elimi
53 quito-transmitted flavivirus that now causes epidemics affecting millions of people on multiple conti
54 The diagnostic response to the 2014-15 Ebola epidemic, although ultimately effective, was slow and ex
55 e routes of HCV infection to reverse the HCV epidemic among HIV-infected MSM.
56 elected to reflect varying stages of the HIV epidemic among MSM and PWID in India.
57 ed the recent Zika virus (ZIKV) infection an epidemic and a public health emergency of global concern
58                               The Zika virus epidemic and associated congenital infections have promp
59 demic influenza A(H1N1) virus (A[H1N1]pdm09) epidemic and concurrent influenza B(Victoria) virus acti
60 ly stockpiled for use in the control of both epidemic and endemic cholera.
61 ession are urgently needed to curtail the AF epidemic and improve outcomes in affected individuals.
62 care and prevention services to curb the HIV epidemic and improve the quality of life of transwomen i
63 e potential magnitude and timing of the ZIKV epidemic and it can be potentially used as a template fo
64 s found in nature and the formation of novel epidemic and pandemic IAV strains.
65 e implications for vaccination and influenza epidemic and pandemic mitigation strategies.
66  current landscape of the heart failure (HF) epidemic and provide targets for future health policy in
67 Epidemiological data from the 2002-2003 SARS epidemic and recent Middle East respiratory syndrome out
68 quired an A82V change during the West Africa epidemic and that this change altered the capacity of GP
69 tion (WHO), has committed to ending the AIDS epidemic and to ensuring that 90% of people living with
70 ort-term surveillance that focuses on single epidemics and acutely ill individuals, the subtle dynami
71    Influenza A viruses (IAVs) cause seasonal epidemics and occasional pandemics, representing a serio
72 rus is an airborne pathogen causing seasonal epidemics and occasional pandemics.
73                 The imminent threat of viral epidemics and pandemics dictates a need for therapeutic
74  large public health burden through seasonal epidemics and sporadic pandemics.
75  help China change the trajectory of its HIV epidemic, and help to achieve the goal of an end to AIDS
76       Pre-diabetes and diabetes are a global epidemic, and the associated neuropathic complications c
77  are driving the ongoing global tuberculosis epidemic, and there is a pressing need for research focu
78 inia 1994 (VA1994), the index isolate of the epidemic, and Virginia 2013 (VA2013), a recent isolate o
79 d the epidemiological characteristics across epidemics, and estimated the risk of death, mechanical v
80  used to forecast invasive bacterial disease epidemics, and simple control measures to reduce particu
81  the evolutionary trajectories driving these epidemics are replicated using a simple cell-based exper
82 tein (GP) that occurred early in the 2013-16 epidemic, are suspected to confer a selective advantage
83 contributors to the growing sleep deficiency epidemic, as is the high prevalence of sleep disorders l
84 th severe congenital malformations, the ZIKV epidemic became an imperative for mobilization, renewed
85                           The 2016-17 A H7N9 epidemic began earlier, spread to more districts and cou
86 he degree distribution is not independent of epidemics but is shaped through disease-induced dynamics
87 dominated among regions affected by the ZIKV epidemic, but the spectrum of neurological disease in th
88  lessen the multidrug-resistant tuberculosis epidemic, but this effect depends on its long-term effic
89                   The 2013-2015 West African epidemic, by far the most geographically extensive, most
90 idium difficile infection through dysbiosis, epidemic C difficile ribotypes characterised by multidru
91                                              Epidemics caused by the reemergence of Zika virus (ZIKV)
92  disease that differs epidemiologically from epidemic cholera.
93 erinvasive meningococci, suggesting that the epidemic clones emerged by acquisition of pre-existing m
94 nity have remained unchanged, distinct A:cc5 epidemic clones have nevertheless emerged.
95 ierarchical cluster analysis, we identify 21 epidemic clusters, of which 12 were cross-regional.
96 patients infected with A H7N9 in the 2016-17 epidemic compared with previous epidemics.
97 environmental patterns associated with these epidemics, comparing human and ruminant serological data
98 be sufficient when data-limited estimates of epidemic consequences are necessary.
99 hat a phylogeny reveals about the underlying epidemic contact network.
100 wed us to detect specific events, like wars, epidemics, coronations, or conclaves, with high accuracy
101 t begomoviruses characterized from the first epidemic; Cotton leaf curl Multan virus, Cotton leaf cur
102  trial conducted in Guinea during the recent epidemic demonstrated that a recombinant VSV where G pro
103                                      Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea an
104                                      Porcine epidemic diarrhea virus (PEDV) is a devastating cause of
105                           We address why the epidemic did not spread into neighbouring countries, sho
106                    Shortages of vaccines for epidemic diseases, such as cholera, meningitis, and yell
107 of chronic shedding relative to more obvious epidemic drivers, and poor ability to differentiate betw
108                                 A Zika virus epidemic emerged in northeast Brazil in 2015 and was fol
109                            In the wake of an epidemic, established immunity against a particular dise
110                     We found two overlapping epidemic events of infection in which most pigs (98.4%)
111 llows to assess the danger of self-sustained epidemics from any viral sequence data.
112 noroviruses (HNoVs) are the leading cause of epidemic gastroenteritis worldwide.
113                 The recent Zika virus (ZIKV) epidemic has been linked to unusual and severe clinical
114                 Although the current obesity epidemic has been well documented in children and adults
115                 The recent Zika virus (ZIKV) epidemic has created an urgent need for a safe and effec
116                        The Zika virus (ZIKV) epidemic has profoundly affected the lives of children a
117                        The Zika virus (ZIKV) epidemic has resulted in congenital abnormalities in fet
118 nd adverse disease outcomes of the 2015-2016 epidemic have elevated ZIKV from a previously understudi
119 poradic clusters at the end of the 2013-2016 epidemic have prompted recommendations that male survivo
120                       During the 2014 EV-D68 epidemic, high rates of pediatric hospitalizations and E
121                                          The epidemic history of Zika virus began in 2007, with its e
122                      However, the origin and epidemic history of ZIKV in Brazil and the Americas rema
123           An RT-RPA assay targeting a recent epidemic human norovirus strain (GII.4 New Orleans) was
124 ise for sensitive point-of-care detection of epidemic human norovirus, and is the fastest human norov
125 rticularly the Syrian conflict and the Ebola epidemic, I recommend four sets of actions that would ma
126 ed research completed during the west Africa epidemic, identify ongoing knowledge gaps, and suggest p
127                    However, during a measles epidemic in 2013-2014, MMR vaccination was also offered
128                                Overweight is epidemic in adolescents and is a major concern because i
129 F01_AE strains primarily responsible for the epidemic in Asia.
130 ana played a pivotal role in the Chikungunya epidemic in Brazil and was one of the first urban centre
131 y extensive, most fatal, and longest lasting epidemic in Ebola's history, presented an enormous inter
132 ern Pacific, followed in 2013-14 by a larger epidemic in French Polynesia, south Pacific, where the f
133  threat to long-term control of the HIV-AIDS epidemic in low- and middle-income countries (LMICs).
134 lining epidemic overall but with a large sub-epidemic in MSM and male sex workers, an optimal prevent
135 drug-resistance, drives the MDR tuberculosis epidemic in Shanghai, China.
136                                Other than an epidemic in South America due to a closely related strai
137 an index case can escalate into a widespread epidemic in the absence of intervention (eg, Nigeria and
138        Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects h
139                        The Zika virus (ZIKV) epidemic in the Americas poses a public health emergency
140 irus infection risk during the course of the epidemic in the region.
141 in-resistant Staphylococcus aureus (CA-MRSA) epidemic in the United States is largely attributable to
142                      Amid the current opioid epidemic in the United States, the enhanced recovery aft
143                  The demographics of the HIV epidemic in the USA have shifted towards older age.
144       The human immunodeficiency virus (HIV) epidemic in Ukraine has been driven by a rapid rise amon
145                The recent Ebola virus (EBOV) epidemic in West Africa demonstrates the potential for a
146 n responsible for recent large and sustained epidemics in Asia and Latin America.
147 rovirus variant caused major gastroenteritis epidemics in China in 2014 to 2016.
148 ynamic transmission model of multi-strain TB epidemics in hypothetical populations reflective of the
149 uth disease (FMD) can cause large disruptive epidemics in livestock.
150 ch was needed to identify the drivers of RVF epidemics in Madagascar.
151  have become endemic or have caused dramatic epidemics in many parts of the world.
152 may be responsible for the initiation of CLS epidemics in mixed-cropping farms, whereas external sour
153 a has experienced two of the largest cholera epidemics in modern history; one in 1991 and the other i
154 pens a new window for studying the recurrent epidemics in multi-layered networks.
155                              HMPV appears in epidemics in Norwegian children, with a hospitalization
156 s C virus subtypes 4a (HCV4a) and 4d (HCV4d) epidemics in Saudi Arabia.
157 caused three successive pandemics, including epidemics in sub-Saharan Africa.
158 neage of ZIKV was responsible for the recent epidemics in the Americas.
159 urces of inoculum may be contributing to CLS epidemics in the monoculture fields in New York.
160  of the populations with the most severe HIV epidemics in the world.
161 rkov model to represent India's tuberculosis epidemic, including a probabilistic framework reflecting
162 ry year, which is comparable to recent acute epidemics, including the 2014 Ebola and 2015 Zika epidem
163            This change accounts for seasonal epidemics, infrequent pandemics, and zoonotic outbreaks.
164 l status of marijuana, addressing the opioid epidemic, insurance coverage of substance use disorders
165 or, this disparity, to integrate concomitant epidemics into models, and to understand reasons for rac
166 Moreover, the phylogeny showed two different epidemic introductions in 2008 and 2009.
167 t gammaretrovirus infections, yet no current epidemic is evident, despite environmental exposure to v
168 mission from a concentrated to a generalized epidemic is of major importance for public health.
169                     To stop the tuberculosis epidemic, it is critical that we interrupt tuberculosis
170  three time periods: pre-Ebola virus disease epidemic (January, 2013, to February, 2014), during-epid
171  surveillance system revealed an increase of epidemic keratoconjunctivitis (EKC) from an average of 3
172            Opiate abuse and overdose reached epidemic levels in the United States.
173 s sensu lato (brown dog ticks) as drivers of epidemic levels of Rocky Mountain spotted fever.
174 spread varied across seasons, seven of eight epidemics likely originated in the Southern US.
175 tance, there is a strong bias for sequencing epidemic lineages of methicillin-resistant Staphylococcu
176  each of these two toxins to pathogenesis of epidemic M1 or M89 strains remains unexplored.
177   Herein, using a genetically representative epidemic M1 strain and a panel of isogenic mutant deriva
178  HIV transmission associated with the opioid epidemic make cost-effective programs for people who inj
179 hough the ZEBOV variant responsible for this epidemic (Makona) shares significant genetic similarity
180 c (January, 2013, to February, 2014), during-epidemic (March, 2014, to February, 2015) and post-epide
181 ic (March, 2014, to February, 2015) and post-epidemic (March, 2015, to Feb, 2016).
182                                     Parasite epidemics may be influenced by interactions among symbio
183                            The deterministic epidemic model includes five compartments: colonized and
184                                 A stochastic epidemic model with stochastic simulations is also prese
185 ial distancing measures in an age structured epidemic model.
186                                              Epidemic models that determine which interventions can s
187  It can cause considerable yield losses when epidemics occur.
188               The major turning point in the epidemic occurred in 1995-1996 when combination antiretr
189 ity and duration of care have resulted in an epidemic of caregiver burden.
190  importance of measures to reduce the global epidemic of childhood obesity and encourage mechanistic
191                            There is a hidden epidemic of cognitive dysfunction in the perioperative s
192 ct a gradual transformation from the current epidemic of drug-susceptible tuberculosis to a drug-resi
193 lipotoxicity and may help slow the advancing epidemic of NAFLD in the next generation.
194 , and effective interventions to reverse the epidemic of obesity in women of childbearing age and to
195  United States needs Medicaid to address its epidemic of opioid abuse.
196 drome is rarely diagnosed, given the current epidemic of opioid use, it is likely to be under-recogni
197                                    Given the epidemic of opioid-related morbidity and mortality, it i
198                                   The recent epidemic of pumping and feeding in the United States and
199 ng syndrome in Canada in the early 1990s, an epidemic of severe systemic disease due to PCV2 spread w
200                          Since late 2015, an epidemic of yellow fever has caused more than 7334 suspe
201  We jointly analysed datasets describing the epidemic of yellow fever, vector suitability, human demo
202                                The 2015-2016 epidemic of Zika virus (ZIKV) in the Americas and the Ca
203                             An unprecedented epidemic of Zika virus (ZIKV) infection had spread to So
204                                 A widespread epidemic of Zika virus (ZIKV) infection was reported in
205 jor human pathogen, responsible for seasonal epidemics of acute respiratory illness.
206  the most important viral pathogens, causing epidemics of acute respiratory infection (ARI), especial
207 ) is a mosquito-borne flavivirus that causes epidemics of encephalitis and viscerotropic disease worl
208 man genome sequence, which reveals many past epidemics of gammaretrovirus infection, and from recent
209 orial belt of the African continent to cause epidemics of highly fatal hemorrhagic fever.
210                                  The ongoing epidemics of opioid overdose raises an urgent need for e
211 liovirus eradication is hampered globally by epidemics of vaccine-derived polio.
212                                 The study of epidemics on static networks has revealed important effe
213 for the targeted control of dynamics such as epidemics, or for modifying biochemical pathways relatin
214    Early resolution of uncertainty during an epidemic outbreak can lead to rapid and efficient decisi
215              To assess the ability to detect epidemic outbreaks early, we calculate the time differen
216 oradic outbreaks, the virus has caused major epidemic outbreaks in Africa, Asia, the Indian Ocean, an
217                In the context of a declining epidemic overall but with a large sub-epidemic in MSM an
218 posure to violence continues to be a growing epidemic, particularly among children.
219                   We explore AHSV both as an epidemic pathogen and within its endemic range as a barr
220  of point-of-care diagnostics, quarantine of epidemic pathogens, and prevention of terrorism's bio-at
221  Among them, nine E. coli strains possess an epidemic pCSZ4-like IncX4 plasmid containing mcr-1.
222                 Results showed that the HFMD epidemic peaked in early summer and autumn.
223     Winter holidays delay seasonal influenza epidemic peaks and shift disease risk toward adults beca
224                      HAdV-D8 isolates of the epidemic period had a very high sequence identity of at
225  detected as early as 2010 but not after the epidemic period in 2014.
226  child vaccination completion during the pre-epidemic period was followed by significant immediate an
227 son, eight HAdV-D8 isolates from outside the epidemic period were sequenced.
228      From November 2011 until December 2013 (epidemic period) 85% of typed isolates were human adenov
229                     After adjusting for age, epidemic period, MERS patients with comorbidity had arou
230 s for these indicators increased in the post-epidemic period, the trends for all stagnated.
231 on (19%) of HAdV-D8 was observed outside the epidemic period.
232 birth cohort effects, prior vaccination, and epidemic period.
233 ith standardized protocols conducted outside epidemic periods would help to clarify the circumstances
234                                 For stage 3, epidemic potential, we combined local and international
235 s and could benefit from real-time influenza epidemic prediction web tools such as Google Flu Trends
236 aracterized, hindering refinements of future epidemic predictions and explorations of targeted interv
237  particularly crucial for enabling a general epidemic predictive framework at the individual level.
238 called by immunization.IMPORTANCE The dengue epidemic presents a global public health challenge that
239         Worldwide obesity rates have reached epidemic proportions and significantly contribute to the
240 d atrial fibrillation (AF) are increasing in epidemic proportions, and both increase the prevalence o
241 hey should be carried out in anticipation of epidemics rather than in response to them.
242  a global scale, and the potential for CHIKV epidemics remains high.
243                     Seasonal influenza virus epidemics represent a significant public health burden.
244                                              Epidemics require a paradigm shift in thinking about all
245 tive pressures favouring multidrug-resistant epidemic ribotypes and was associated with substantial d
246 in the incidence of suspected meningitis and epidemic risk, and a substantial effect on confirmed gro
247 nt implication in both genome plasticity and epidemic risk, but the early stages of the infection hav
248 , as has been found for the recently emerged epidemic RT027 lineage.
249 e three benchmark methods in the majority of epidemic scenarios tested.
250 nbiased and robust fitness estimates in most epidemic scenarios.
251                 Nosocomial clones, including epidemic sequence type 258 (ST258), have shown an affini
252  that increased production of SPN and SLO in epidemic serotype M1 and M89 S. pyogenes strains is asso
253 d case sources have changed gradually across epidemics since 2013, while clinical severity has not ch
254 lood donor banks may be useful to anticipate epidemic spread of arboviruses.
255 the susceptible-infective-recovered model of epidemic spread, which combines both agent-to-agent hete
256 ing diffusion on networks, such as rumour or epidemic spreading.
257 e viremic across 26 Indian cities at various epidemic stages.
258 ervation to update the belief about the true epidemic state.
259                           Circulation of the epidemic strain was detected as early as 2010 but not af
260        The 2014-15 Ebola virus disease (EVD) epidemic strained health systems in west Africa already
261 logenetic analysis reveals that contemporary epidemic strains have accumulated multiple substitutions
262           Further analyses showed that these epidemic strains have higher NS1 antigenaemia than the F
263 gnize the K166 area, leading to emergence of epidemic strains with such mutations.
264 ition to the K166Q mutation that occurred in epidemic strains, other HA mutations can confer resistan
265 ective sweep of specific var genes or clonal epidemic structure related to the incidence of uncomplic
266                       If at the start of the epidemic, sufficient vaccines had been available to targ
267 spatial/demographic incidence of the obesity epidemic suggest that economic policies aimed at expandi
268                            During the recent epidemic, tests authorized for emergency use have been u
269        Results also uncovered a misdiagnosed epidemic that implicated beneficial Rhodococcus bacteria
270 e series data collected during the 2009 H1N1 epidemic that includes information about vaccination, fl
271 are the causative agents of annual influenza epidemics that can be severe, and influenza A viruses in
272 est Africa and East/Southern Africa, causing epidemics that lasted up to 28 years.
273 ork that captured dynamics of the Zika virus epidemic, the risk of GBS in Zika virus-infected persons
274                  We found that, for seasonal epidemics, the number of infections averted ranged from
275 a, environmental drivers did not trigger the epidemics: They only modulated local Rift Valley fever v
276  The relative risk of districts reaching the epidemic threshold of ten per 100 000 per week was estim
277 sion among Swiss heterosexuals far below the epidemic threshold.
278 cline in the risk of a district reaching the epidemic threshold.
279 hagic fever in humans and is responsible for epidemics throughout sub-Saharan, central, and West Afri
280 en living with HIV from the beginning of the epidemic to the present.
281 o-layered network model of coupled recurrent epidemics to reproduce the synchronized and mixed outbre
282 haracterized the changes to transmission and epidemic trajectories among children and adults in a spa
283 s provides a unified assessment of potential epidemic trajectories, with the aim of allowing national
284 orks and show that this process exhibits two epidemic transitions corresponding to a core-periphery s
285 s species of mosquitoes and is capable of an epidemic, urban transmission cycle with high rates of in
286   Our results indicate that the start of the epidemic was driven by horizontal dissemination of mobil
287    The west Africa Ebola virus disease (EVD) epidemic was extraordinary in scale.
288 e acquired immune deficiency syndrome (AIDS) epidemic was first recognized in 1981, and it quickly be
289 ividuals admitted to hospital in the 2016-17 epidemic was similar to that in the previous epidemics.
290 cess.IMPORTANCE The West African Ebola virus epidemic was the largest to date, with more than 28,000
291 es of parasite interactions and phenology in epidemics, we embedded multiple cohorts of sentinel plan
292 infection culture, and very few from the HIV epidemic were functional.
293                           We found that both epidemics were the result of intercontinental introducti
294 try spread in shaping the Saudi Arabia HCV4a epidemic, while this may be different for the HCV4d epid
295  abuse and addiction have become a worldwide epidemic with great societal and financial burdens, high
296                     Attempts to control this epidemic with screening programs and antibiotic therapy
297                       Obesity is a worldwide epidemic, with major health and economic costs.
298 n that fuels a diverse array of tuberculosis epidemics worldwide.
299 in our framework), that consider the cost of epidemic years, and that account for productivity and to
300  no longer increased after challenge with an epidemic ZIKV, and completely prevented viremia.

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