ライフサイエンスコーパス: epigallocatechin

1 in presence of flavan-3-ols, epicatechin and epigallocatechin.

2 oids were isolated (1-3): gallocatechin (1), epigallocatechin (2) and epigallocatechin-3-O-gallate (3

3 echin (EGC), epicatechin 3-gallate (ECG) and epigallocatechin 3-gallate (EGCG) and caffeine in 29 com

4 sly, we showed that the green tea polyphenol epigallocatechin 3-gallate (EGCG) inhibits growth of NF6

5 The effect of the polyphenol epigallocatechin 3-gallate (EGCG) on hCT fibrillation wa

6 ted that the major green tea polyphenol, (-)-epigallocatechin 3-gallate (EGCG), exerts potent neuropr

7 abilities of apigenin, baicalein, curcumin, epigallocatechin 3-gallate (EGCG), genistein, quercetin,

8 Epigallocatechin 3-gallate (EGCG), the major polyphenol

9 e we show that the tea-derived flavanol, (-)-epigallocatechin 3-gallate [(2R,3R)-5,7-dihydroxy-2-(3,4

10 By using this system, the natural product epigallocatechin 3-gallate was found to block Wnt signal

11 In a limited phytonutrient screen, EGCG ((-)-epigallocatechin 3-gallate), the major phytochemical in

12 inistration of green tea extracts containing epigallocatechin 3-gallate, a potent DYRK1A inhibitor, t

13 We identified (-)-epigallocatechin 3-O:-gallate, as a potent inhibitor of

14 epimer mixture of (+)-gallocatechin and (-)-epigallocatechin, 3,3'-di-O-methylellagic acid 4'-O-xylo

15 sly, we showed that the green tea polyphenol epigallocatechin-3 gallate (EGCG) inhibits growth and tr

16 ole of green tea polyphenols, the effects of epigallocatechin-3 gallate (EGCG) on Her-2/neu-overexpre

17 ype, the effects of the green tea polyphenol epigallocatechin-3 gallate (EGCG) on mammary tumor cells

18 ecursor N-acetyl-L-cysteine (NAC), curcumin, epigallocatechin-3 gallate (EGCG), and p38 inhibitor SB2

19 nin, celecoxib, and the green tea polyphenol epigallocatechin-3 gallate, induced ERalpha.

20 phanyl-3-butenyl isothiocyanates; G) and (-)-epigallocatechin-3-gallate (E) were investigated in colo

21 Epigallocatechin-3-gallate (EGCG) accounts for almost 50

22 sms of the protection conferred by sugars to epigallocatechin-3-gallate (EGCG) against deterioration.

23 catechin, (-)-epigallocatechin (EGC) and (-)-epigallocatechin-3-gallate (EGCG) and butylated hydroxyt

24 s of two main constituents of green tea, (-)-epigallocatechin-3-gallate (EGCG) and caffeine, on intes

25 s known to modulate its aggregation, such as epigallocatechin-3-gallate (EGCG) and dopamine (DA).

26 Green tea catechins such as (-)epigallocatechin-3-gallate (EGCG) are known to improve e

27 Here, we identify (-)-epigallocatechin-3-gallate (EGCG) as a new inhibitor of

28 Recent reports suggest green tea-derived (-)-epigallocatechin-3-gallate (EGCG) can attenuate neuronal

29 Green tea polyphenol, epigallocatechin-3-gallate (EGCG) differentially regulat

30 we have shown that green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) exerts a beneficial ro

31 It was reported that epigallocatechin-3-gallate (EGCG) exhibits anti-inflamma

32 Green tea-derived polyphenol (-)-epigallocatechin-3-gallate (EGCG) has been extensively s

33 Green tea constituent (-) epigallocatechin-3-gallate (EGCG) has shown remarkable c

34 The biological effects of (-)-epigallocatechin-3-gallate (EGCG) have been extensively

35 (4-hydroxyphenyl) retinamide (4-HPR) and (-)-epigallocatechin-3-gallate (EGCG) in altering expression

36 The polyphenol epigallocatechin-3-gallate (EGCG) in combination with do

37 y was undertaken to evaluate the efficacy of epigallocatechin-3-gallate (EGCG) in down-regulating Mcl

38 of epigenetic bioactive botanicals including epigallocatechin-3-gallate (EGCG) in green tea polypheno

39 We encapsulated green tea polyphenol epigallocatechin-3-gallate (EGCG) in polylactic acid-pol

40 owed that the bioactive green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits growth in sof

41 (-)-Epigallocatechin-3-gallate (EGCG) is a well-known chemop

42 (-)-Epigallocatechin-3-gallate (EGCG) is an important bioact

43 with anti-amyloid agents like the polyphenol epigallocatechin-3-gallate (EGCG) is emerging as an expe

44 The green tea catechin epigallocatechin-3-gallate (EGCG) is generally considere

45 Epigallocatechin-3-gallate (EGCG) is the major polypheno

46 Epigallocatechin-3-gallate (EGCG) is the most biological

47 The green tea component epigallocatechin-3-gallate (EGCG) may be beneficial in a

48 fect of vanillin, resveratrol, curcumin, and epigallocatechin-3-gallate (EGCG) on the aggregation of

49 The cells were incubated with (-)-epigallocatechin-3-gallate (EGCG) or theaflavin-3,3'-dig

50 to scavenge H2O2 (400muM) and influence (-)-epigallocatechin-3-gallate (EGCG) oxidation (400muM) in

51 ract and its main polyphenol constituent (-)-epigallocatechin-3-gallate (EGCG) possess potent neuropr

52 In contrast, epigallocatechin-3-gallate (EGCG) signals ECs via the 67

53 Polyphenon E with a standardized dose of epigallocatechin-3-gallate (EGCG) was administered using

54 Of the various GrTPs, (-)-epigallocatechin-3-gallate (EGCG) was the most potent in

55 major effective component in green tea, (-)-epigallocatechin-3-gallate (EGCG)'s potential benefits t

56 major green tea polyphenols (catechins), (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin,

57 resent study, we investigated the effects of epigallocatechin-3-gallate (EGCG), a bioactive green tea

58 (-)-Epigallocatechin-3-gallate (EGCG), a catechin found in g

59 In vitro and in vivo treatment with Epigallocatechin-3-gallate (EGCG), a Dyrk1a inhibitor, m

60 d antioxidants included three phenolics: (-)-epigallocatechin-3-gallate (EGCG), a flavanoid polypheno

61 We have reported previously that (-)-epigallocatechin-3-gallate (EGCG), a green tea polypheno

62 the present study, we examined the effect of epigallocatechin-3-gallate (EGCG), a green tea polypheno

63 on CLL B cells, and we studied the impact of epigallocatechin-3-gallate (EGCG), a known receptor tyro

64 Epigallocatechin-3-gallate (EGCG), a main catechin of gr

65 (-)-Epigallocatechin-3-gallate (EGCG), a major component of

66 Recent studies have shown that epigallocatechin-3-gallate (EGCG), a major constituent o

67 (-)-Epigallocatechin-3-gallate (EGCG), a major polyphenol co

68 Epigallocatechin-3-gallate (EGCG), a polyphenol extracte

69 Treatment with epigallocatechin-3-gallate (EGCG), a polyphenolic compou

70 nefits of green tea are mainly attributed to epigallocatechin-3-gallate (EGCG), a polyphenolic compou

71 as conducted to determine to what extent (-)-epigallocatechin-3-gallate (EGCG), a widely used dietary

72 We found that epigallocatechin-3-gallate (EGCG), an anti-inflammatory

73 rions, Sindbis virus, and the polyphenol (-)-epigallocatechin-3-gallate (EGCG), and has been implicat

74 ation (1-500 muM) of a model polyphenol, (-)-epigallocatechin-3-gallate (EGCG), and matrix pH (2-7) o

75 muscle for the major green tea catechin, (-)-epigallocatechin-3-gallate (EGCG), but effects were obse

76 effect of two small molecules, FK506 and (-)-epigallocatechin-3-gallate (EGCG), known to inhibit alph

77 ea extract (GTE) and its major catechin, (-)-epigallocatechin-3-gallate (EGCG), on collagen homeostas

78 larly its major polyphenolic constituent (-)-epigallocatechin-3-gallate (EGCG), possesses remarkable

79 bond-containing tea polyphenols, such as (-)-epigallocatechin-3-gallate (EGCG), potently and specific

80 yphenols (GTPP) and their active ingredient, epigallocatechin-3-gallate (EGCG), protects cells from s

81 eritoneal (i.p.) injection (20 mg/kg) of (-)-epigallocatechin-3-gallate (EGCG), the main polyphenolic

82 Here, we report that (-)-epigallocatechin-3-gallate (EGCG), the main polyphenolic

83 We reported previously that (-)-epigallocatechin-3-gallate (EGCG), the major and most ac

84 Epigallocatechin-3-gallate (EGCG), the major constituent

85 Here, we provide evidence that epigallocatechin-3-gallate (EGCG), the major polyphenol

86 n previously that topical application of (-)-epigallocatechin-3-gallate (EGCG), the major polyphenol

87 e and animal model studies indicate that (-)-epigallocatechin-3-gallate (EGCG), the major polyphenol

88 We report herein that (-)-epigallocatechin-3-gallate (EGCG), the major polyphenol

89 Here, we report for the first time that epigallocatechin-3-gallate (EGCG), the major polyphenoli

90 Epigallocatechin-3-gallate (EGCG), the major tea polyphe

91 Epigallocatechin-3-gallate (EGCG), the most abundant GTP

92 (-)-Epigallocatechin-3-gallate (EGCG), the principal polyphe

93 Epigallocatechin-3-gallate (EGCG), the principal polyphe

94 Epigallocatechin-3-gallate (EGCG), the principal polyphe

95 ion by two dietary polyphenols, curcumin and epigallocatechin-3-gallate (EGCG), with that by the endo

96 ed to its major polyphenolic constituent (-) epigallocatechin-3-gallate (EGCG).

97 presence of a well-described polyphenol, (-)-epigallocatechin-3-gallate (EGCG).

98 d reactivities of the green tea extract, (-)-epigallocatechin-3-gallate [(2R,3R)-5,7-dihydroxy-2-(3,4

99 showed that 3-d supplementation of combined epigallocatechin-3-gallate and resveratrol (EGCG+RES) in

100 h tea polyphenols or the major tea component epigallocatechin-3-gallate blocked expression of the hyp

101 ergies for (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate for the binding site on BSA n

102 Therapy using the DYRK1A inhibitor epigallocatechin-3-gallate improved Ts65Dn skeletal phen

103 biologically active green tea catechin, (-)-epigallocatechin-3-gallate or (-)-EGCG, has been shown t

104 ) at pH 7.5 and 25 degrees C: catechins [(-)-epigallocatechin-3-gallate, (-)-epigallocatechin, (-)-ep

105 Epigallocatechin-3-gallate, a potent Mnb/Dyrk1A inhibito

106 We recently showed that (-)-epigallocatechin-3-gallate, a tea polyphenol, not only i

107 nts, such as the vitamin E analog trolox and epigallocatechin-3-gallate, enhanced hypoxia-induced cas

108 e candidate compounds: rifampicin, curcumin, epigallocatechin-3-gallate, myricetin, and scyllo-inosit

109 Studies from our laboratory have shown that epigallocatechin-3-gallate, the major polyphenol present

110 oxaldehyde, ferulic acid, vanillic acid, and epigallocatechin-3-gallate, were effective inhibitors of

111 modified quenching constant, followed by (-)-epigallocatechin-3-gallate.

112 nterventions provided similar amounts of (-)-epigallocatechin-3-gallate.

113 ea polyphenol preparation containing 65% (-)-epigallocatechin-3-gallate] and caffeine on 4-(methylnit

114 gallocatechin (1), epigallocatechin (2) and epigallocatechin-3-O-gallate (3).

115 (-)-Epigallocatechin-3-O-gallate (EGCG), a major ingredient

116 The major constituent of green tea, (-)-epigallocatechin-3-O-gallate (EGCG), has been shown to h

117 polyphenols [catechin, epicatechin, and (-)-epigallocatechin-3-O-gallate (EGCG)] and bioflavonoids (

118 en tea catechin derivative, oligomerized (-)-epigallocatechin-3-O-gallate (OEGCG) as a carrier for or

119 ld) and caffeic (1.7-fold) acids, as well as epigallocatechin (63-fold), rutin (41-fold) and querceti

120 UPLC-MS analysis led to identify epigallocatechin and quercetin derivatives from banana a

121 ratio, and by a polyphenolic profile poor in epigallocatechin and rich in catechin-rich tannins.

122 Fe(II), lipoic acid, pectin, epigallocatechin and thiamine are also effective for Hg(

123 ns, mainly because of the high values of (-)-epigallocatechin and trans-caftaric acid.

124 tes (OCRs) are faster with higher copper and epigallocatechin contents and with higher absorbance at

125 On the contrary, total anthocyanin and epigallocatechin contents were negatively correlated wit

126 B, and lower levels of (-)-epicatechin, (-)-epigallocatechin (EGC) and (-)-epigallocatechin gallate

127 B, and lower levels of (-)-epicatechin, (-)-epigallocatechin (EGC) and (-)-epigallocatechin gallate

128 erties of (+)-catechin, (-)-epicatechin, (-)-epigallocatechin (EGC) and (-)-epigallocatechin-3-gallat

129 ffeine content followed by epicatechin (EC), epigallocatechin (EGC) and to some extent in other chemi

130 f specific catechins, including epicatechin, epigallocatechin (EGC), and 4'-O-methyl-epigallocatechin

131 ents, namely catechin (C), epicatechin (EC), epigallocatechin (EGC), epicatechin 3-gallate (ECG) and

132 (-)-Epigallocatechin (EGC), however, completely repressed HG

133 atechin-gallate-enriched extract (EGCGe) and epigallocatechin-enriched extract (EGCe).

134 s to an antioxidant activity (r>0.7111) were epigallocatechin, epicatechin and rutin; while epicatech

135 , (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin, (-)-epicatechin-3-gallate, (-)-epicate

136 techins [(-)-epigallocatechin-3-gallate, (-)-epigallocatechin, (-)-epicatechin-3-gallate], flavones (

137 howed higher levels of catechins (especially epigallocatechin galate, epicatechin gallate, and epicat

138 The pH 4.5 induced higher decrease in (-)-epigallocatechin gallate (71% and 79%) and quercetin-3-g

139 , with (+)-catechin, (-)-epicatechin, or (-)-epigallocatechin gallate (EGCG) added as chain breakers.

140 ACS67, ACS1, and the antioxidant epigallocatechin gallate (EGCG) all stimulated GSH level

141 that two of the polyphenols from green tea (epigallocatechin gallate (EGCG) and epicatechin gallate

142 Of the four compounds tested, epigallocatechin gallate (EGCG) and epicatechin gallate

143 us green tea constituents, in particular (-)-epigallocatechin gallate (EGCG) and other polyphenols wi

144 We show that the polyphenolic compounds epigallocatechin gallate (EGCG) and silibinin bind to sp

145 (-)-Epigallocatechin gallate (EGCG) and theaflavins are beli

146 special, hitherto-unexplored property of (-)-epigallocatechin gallate (EGCG) as a chiral solvating ag

147 The STAT1 inhibitor epigallocatechin gallate (EGCG) attenuated STAT1 phospho

148 etermine whether an ingredient of green tea, epigallocatechin gallate (EGCG) could attenuate oxidativ

149 (-)-Epigallocatechin gallate (EGCG) effectively reduces the

150 y-Arg-Pro-Pro-Gln-Gly and the polyphenol (-)-epigallocatechin gallate (EGCG) has been determined usin

151 The flavonoid epigallocatechin gallate (EGCG) has previously been show

152 The encapsulation of green tea catechin and epigallocatechin gallate (EGCG) in soy lecithin liposome

153 ons of the tea catechins epicatechin (EC) or epigallocatechin gallate (EGCG) inhibited formation of h

154 Epigallocatechin gallate (EGCg) is a major form of tea c

155 Epigallocatechin gallate (EGCG) is a major polyphenol in

156 microscopy (AFM), that the commonly used (-)-epigallocatechin gallate (EGCG) is a much less efficient

157 Epigallocatechin gallate (EGCG) is a powerful antioxidan

158 ory have demonstrated that the GT polyphenol epigallocatechin gallate (EGCG) is capable of antagonizi

159 Epigallocatechin gallate (EGCG) is often described as th

160 (-)-Epigallocatechin gallate (EGCG) is one of the major gree

161 Epigallocatechin gallate (EGCG) is the major active poly

162 Epigallocatechin gallate (EGCG) is the major component o

163 en tea extract (GTE) supplementation high in epigallocatechin gallate (EGCG) on blood lipids in healt

164 luence of the polyphenolic amyloid inhibitor epigallocatechin gallate (EGCG) on the aggregation pathw

165 pared to standard green tea shoot (GL) while epigallocatechin gallate (EGCG) recorded higher levels i

166 t higher levels of the catechins, especially epigallocatechin gallate (EGCG) were found in green teas

167 Epigallocatechin gallate (EGCG), a bioactive polyphenol

168 study was to examine whether the antioxidant epigallocatechin gallate (EGCG), a catechin-base flavono

169 aim of this study was to provide support for epigallocatechin gallate (EGCG), a component of green te

170 antly, we also identified in this study that epigallocatechin gallate (EGCG), a green tea-derived cat

171 (-)-Epigallocatechin gallate (EGCG), a major biologically ac

172 cently demonstrated that the antioxidant (-)-epigallocatechin gallate (EGCG), a major component in gr

173 Epigallocatechin gallate (EGCg), a major form of tea cat

174 Epigallocatechin gallate (EGCG), a major form of tea cat

175 nhibitory effects of curcumin, caffeine, (-)-epigallocatechin gallate (EGCG), and tea in animal model

176 acid, caffeic acid, caffeine, curcumin, (-)-epigallocatechin gallate (EGCG), gallic acid, propyl gal

177 omponent of green tea extracts, catechin (-)-Epigallocatechin gallate (EGCg), has been reported to be

178 Indian medicine and the green tea flavonoid, epigallocatechin gallate (EGCG), is reported to have glu

179 catechin, (-)-epigallocatechin (EGC) and (-)-epigallocatechin gallate (EGCG), respectively.

180 catechin, (-)-epigallocatechin (EGC) and (-)-epigallocatechin gallate (EGCG), respectively.

181 Epigallocatechin gallate (EGCg), the main antimicrobial

182 this hypothesis, we evaluated the effect of epigallocatechin gallate (EGCG), the main antioxidant de

183 Epigallocatechin gallate (EGCG), the major polyphenol in

184 We tested the effect of a pure form of epigallocatechin gallate (EGCG), the major polyphenol in

185 one of the main tea flavan-3-ol substrates, epigallocatechin gallate (EGCG), was employed.

186 foraphane, benzyl isothiocyanate (BITC), and epigallocatechin gallate (EGCG).

187 he catechin-binding site of SULT1A1 bound to epigallocatechin gallate (EGCG).

188 opically with caffeine (6.2 micromol) or (-)-epigallocatechin gallate (EGCG; 6.5 micromol) once a day

189 sed, and when treated with 20 micromol/L (-)-epigallocatechin gallate (green tea) was restored back t

190 Catechins [(-)-epigallocatechin gallate and (-)-epicatechin gallate)] w

191 hemolysis while (-)-epicatechin gallate, (-)-epigallocatechin gallate and (-)-epigallocatechin protec

192 also show that addition of the antioxidants epigallocatechin gallate and alpha-lipoic acid reduces p

193 are inhibited by the green tea polyphenols, epigallocatechin gallate and epicatechin gallate.

194 control model beverages were incubated with epigallocatechin gallate and green tea extract at 62 or

195 Interestingly, whereas epigallocatechin gallate and heparin prevent membrane da

196 lly relevant Abeta oligomers is inhibited by epigallocatechin gallate and increased by the A2V mutati

197 ment Abeta(25-35) by two amyloid inhibitors (epigallocatechin gallate and scyllo-inositol) that are c

198 The green tea polyphenol (-)-epigallocatechin gallate and the red wine extract resver

199 Recently, (-)-epigallocatechin gallate has been found to be a potent i

200 Epigallocatechin gallate has been shown to be an inhibit

201 0.3 muM, which was smaller than that of (-)-epigallocatechin gallate in Phase III clinical trials an

202 asured, confirming the major contribution of epigallocatechin gallate in the peroxyl radical scavengi

203 ls tested, TF-2 and, to a lesser degree, (-)-epigallocatechin gallate inhibited cyclooxygenase (Cox)-

204 ine levels that were dose dependent, whereas epigallocatechin gallate levels did not accumulate nor a

205 nhibition of Bcl-2 by the green tea compound epigallocatechin gallate results in an increase in [Ca(2

206 and lactate and the thermosensitive compound epigallocatechin gallate were recovered without signific

207 Administration of dexamethasone, epigallocatechin gallate, alpha-phenyl-N-tert-butyl nitr

208 (125-1,000 ppm), including (+)-catechin, (-)-epigallocatechin gallate, and green tea extract were add

209 that the astringent- and bitter-tasting (-)-epigallocatechin gallate, bitter-tasting caffeine, and t

210 The experiments reveal that polyphenols (epigallocatechin gallate, bromophenol blue, and resverat

211 quillaja saponin and polyphenols (vanillin, epigallocatechin gallate, green tea extract, and protoca

212 ertain tea polyphenols, such as catechin and epigallocatechin gallate, have been used to augment the

213 Contrary, epigallocatechin gallate, pelargonidin and catechin, wit

214 Treatment of glioma cells with (-)-epigallocatechin gallate, which targets the ATP-binding

215 We hypothesized that prostate tumor specific epigallocatechin-gallate (EGCg) functionalized radioacti

216 nt with Dyrk1A inhibitor, green tea flavonol epigallocatechin-gallate (EGCG), from gestation to adult

217 It was hypothesized that epigallocatechin-gallate (EGCG), the main catechin prese

218 rahydrofolate (l-5-MTHF) in combination with epigallocatechin-gallate-enriched extract (EGCGe) and ep

219 ined through assay of urinary GTC metabolite epigallocatechin glucuronide.

220 Wines consuming SO2 efficiently consume more epigallocatechin, prodelphinidins and procyanidins.

221 allate, (-)-epigallocatechin gallate and (-)-epigallocatechin protected at lowest concentrations agai

222 Ascorbic acid, (+)-catechin, (-)-epigallocatechin, tannic acid, and caffeic acid were sel

223 altered the binding of the small polyphenol epigallocatechin to hydroxyapatite.

224 other identified phenolic compounds, whereas epigallocatechin was the lowest for all investigated lea

225 For PA extension subunits, changes in epigallocatechin were inversely correlated with epicatec

226 hin, epigallocatechin (EGC), and 4'-O-methyl-epigallocatechin, were measured in urine specimens that

227 n particular, incubation of epicatechin with epigallocatechin with tyrosinase gave a high, stable the