ライフサイエンスコーパス: epimerize

1 m by which donor-acceptor norbornene systems epimerize.

2 e related 1-(4-nitrophenyl) cis diastereomer epimerized.

3 lyketide synthase (PKS) modules that produce epimerized (2S)-2-methyl-3-ketoacyl-ACP (acyl carrier pr

4 that are implicated in the generation of C2-epimerized (2S)-2-methyl-3-ketoacyl-ACP intermediates.

5 to give a carbapenam, which is subsequently epimerized and desaturated to give a carbapenem in a Car

6 Erythrose 4-phosphate is epimerized and/or isomerized to threose 4-phosphate, whi

7 roposed alginate biosynthetic scaffold while epimerizing approximately every second d-mannuronate res

8 or example, 2-ketothiazoles 4 and 59 readily epimerize at pH 7.4, although they are fairly stable ste

9 the presence of weak acids, these complexes epimerize at the stereogenic carbon bonded to palladium.

10 Monomeric Fapy-dA readily epimerized at 25 degrees C in phosphate buffer (pH 7.5).

11 The 1-(4-methoxyphenyl) cis diastereomer epimerized at a much faster rate into the corresponding

12 2-epi-5-epi-Valiolone is first epimerized at C-2 to give 5-epi-valiolone and then dehyd

13 In the presence of serum, rustmicin rapidly epimerizes at the C-2 position and is converted to a gam

14 Ala; and (iii) a small group of enzymes that epimerize cationic dipeptides.

15 nding macrolactones, while pentaketides with epimerized chiral centers were poorly processed by PikAI

16 panation, followed by ester hydrolysis under epimerizing conditions.

17 cluding one from Cytophaga hutchinsonii that epimerizes D-Ala-D-Ala; and (iii) a small group of enzym

18 the enolase superfamily that are involved in epimerizing dipeptides.

19 etase that synthesizes HC-toxin has only one epimerizing domain for conversion of L-Pro to D-Pro; the

20 from L-Phe but unimpaired from D-Phe; N975A epimerizes faster than Y976A from L-Phe.

21 g on a variety of animal-derived sulfated or epimerized GAGs.

22 The epimerized hexaketide failed to undergo cyclization and

23 m molecular dynamics simulations showing the epimerized hexaketide was accommodated within the Pik TE

24 gain-of-function processing of an unnatural, epimerized hexaketide.

25 These lesions readily epimerize in water, an unusual property for nucleosides.

26 stitution on the cyclohexanone ring was then epimerized into its thermodynamically stable cis counter

27 he holo-thiolation (holo-T) domain, and then epimerizing it (by epimerization domain) to the D-Phe-S-

28 n observed for parallel incubations using an epimerizing ketoreductase domain and the nonepimerizing

29 hydroxypentanoyl-SACP ([2-(2)H]-1a) with the epimerizing ketoreductase domain EryKR1 in the presence

30 -methyl-3-hydroxypentanoyl-SACP with the non-epimerizing ketoreductase domains EryKR6 and TylKR1, res

31 in (Pik) system, preventing the formation of epimerized macrolactones.

32 Synthesis of an analogous hexaketide with an epimerized nucleophilic hydroxyl group allowed for direc

33 hile not required for recognition, cannot be epimerized or substituted.

34 nt-derived deuterium resides solely with the epimerized product (not substrate) in isomerizations car

35 fragments include more heavily sulfated and epimerized regions and, as with the endothelial HS chain

36 acterize a line of knockout mice that cannot epimerize the 3beta-hydroxyl group of cholesterol and as

37 ility of the E domain in the TycB3 module to epimerize the aminoacyl thioester Phe-S-TycB3 and the di

38 The PchE subunit does not epimerize the Cys-S-enzyme intermediate, but once amide

39 While the initiation module clearly epimerizes the aminoacyl thioester Phe1-S-TycA intermedi

40 f-life to longer than 24 hours and some EGCG epimerized to (+)-gallocatechin-3-gallate.

41 idine ring but in the pentose ring, which is epimerized to arabinose in the minor product.

42 ing-fused perhydroquinoline 15 that could be epimerized to its trans-fused counterpart 2 on sequentia

43 hanistic probe 5-fluorouridine that had been epimerized to the arabino isomer suggested that the Psi

44 driven process, the cis-piperidionone 16a is epimerized to the desired trans isomer 16b, which is dir

45 he mixture of the anti and syn diastereomers epimerized to the syn hydroxy ester during the oxido-red

46 ng the GalNAc salvage pathway, UDP-GalNGc is epimerized to UDP-GlcNGc, which might compete with the e

47 ylglucosamine (UDP-GlcNAc) precursor that is epimerized to UDP-N-acetylmannosamine (UDP-ManNAc) and t

48 biosynthetic enzymes to UDP-GalNAz and then epimerized to UDP-N-azidoacetylglucosamine (GlcNAz).

49 acturonate and UDP-D-glucuronate but did not epimerize UDP-D-Glc or UDP-D-Xyl.

50 t of Escherichia coli, and has been shown to epimerize UDP-galactose to UDP-glucose without the addit