ライフサイエンスコーパス: episodic

1 y is that an individual may have an impaired episodic ability to plan for the future.

2 In addition to episodic acute pain, patients with SCD also report chron

3 sing such data is challenging because of its episodic and heterogeneous nature.

4 Radiation-induced impairments in spatial, episodic and recognition memory were temporally coincide

5 angular gyrus (AnG) in the retrieval of both episodic and semantic information, but the region's prec

6 tinct AnG subregions during the retrieval of episodic and semantic information.

7 r gyrus (AnG) contribute to the retrieval of episodic and semantic memories.

8 Human participants completed episodic and semantic memory tasks involving unimodal (a

9 F-AV-1451) positron emission tomography, and episodic and semantic memory, language, executive and vi

10 ion and whether that function differs across episodic and semantic retrieval have yet to be determine

11 exhibited corresponding activity during both episodic and semantic retrieval, which mirrored the func

12 AnG in multimodal feature integration during episodic and semantic retrieval.

13 hippocampus has long been implicated in both episodic and spatial memory, however these mnemonic func

14 le density) and directly with performance in episodic and working memory tasks, suggesting its role i

15 rapy (MPH) can improve aspects of attention, episodic and working memory, and executive functioning a

16 hift delivery of ambulatory care from acute, episodic, and reactive encounters, to proactive, planned

17 ns where annual crop production suffers from episodic aridity.

18 Patients with Type 6 episodic ataxia (EA6) have mutations of the excitatory a

19 Episodic ataxia is an autosomal dominant ion channel dis

20 We studied a mutation found in episodic ataxia of the dual-function glutamate transport

21 A heterozygous mouse model of episodic ataxia type 1 harboring a dominant Kv1.1 mutati

22 Episodic ataxia type 1 is caused by missense mutations o

23 netically heterogeneous and is classified as episodic ataxia type 2 (EA2) when it is caused by a muta

24 ns in the human CaV2.1 subunit are linked to episodic ataxia type 2 (EA2), a dominantly inherited dis

25 t are associated with the cerebellar disease episodic ataxia type 2 (EA2).

26 Episodic ataxia type 2 is caused by mutations in CACNA1A

27 rom five families with genetically confirmed episodic ataxia type 2 underwent neurophysiological asse

28 have been associated with the human disorder Episodic Ataxia Type-1 (EA1), characterized by stress-in

29 portant for neurological diseases related to episodic ataxia, such as hemiplegia, migraine, and epile

30 ons, in 49 unrelated patients diagnosed with episodic ataxia.

31 iency terminals depress significantly during episodic bursts of activity.

32 subfield atrophy was associated with severe episodic but not semantic amnesia for postmorbid autobio

33 observe their exploration and to analyze the episodic Ca(2+) oscillations involved in refinement.

34 everal hours during late embryogenesis, with episodic Ca(2+) signals present in both motile filopodia

35 ied fee-for-service or address procedural or episodic care, but population models are also emerging.

36 rs with the own patient panels or delivering episodic care-within their organizations and understand

37 nels, whereas in other settings they deliver episodic care.

38 ions, 10 of which are associated with florid episodic CNS clinical syndromes in addition to periphera

39 guous or uncertain threats and in preserving episodic content of remote aversive memories in hippocam

40 that were preceded by an event sequence with episodic content.

41 Of these cases, 332 had associated episodic cost data.

42 ,281-$22,812) whereas high compliance had an episodic cost of $15,272 (95% CI, $14,354-$16,192).

43 Low compliance had an average episodic cost of $20,046 (95% CI, $17,281-$22,812) where

44 l-killing under therapeutic perfusion versus episodic delivery.

45 his transfer is accompanied by a decrease in episodic detailedness.

46 In addition, the time-dependent erosion of episodic details of traumatic memories might contribute

47 Our patients produced marginally fewer episodic details than controls.

48 egration of related memories and recovery of episodic details.

49 cantly reduced the number of internal (i.e., episodic) details produced during the simulation and mem

50 We hypothesize that in a range of chronic episodic diseases, indicators of critical slowing down,

51 t acute attacks and exacerbations in chronic episodic disorders such as asthma, cardiac arrhythmias,

52 This Ca decline was not a result of serial episodic disturbances but instead the gradual weathering

53 tes (ABS) of class II were under positive or episodic diversifying selection, compared with only 10%

54 dicated association of rs11720469 with heavy episodic drinking (frequency of consuming 5+ drinks with

55 decreased NASH and fibrosis; however, heavy episodic drinking may accelerate fibrosis progression an

56 for an increased risk associated with heavy episodic drinking, especially among moderate lifetime dr

57 ry, we captured indoor signatures of outdoor episodic emissions arising from nonroutine operations of

58 ported hourly activity data show that midday episodic emissions from manual liquid unloadings (a rout

59 sing a novel serial cue paradigm showed that episodic encoding is dependent on both the LPP and the e

60 ight onto the neural mechanisms that promote episodic encoding not only for information within the ev

61 ic knowledge affect the neural correlates of episodic encoding, assessing medical students 3 months b

62 Coronal mass ejections (CMEs) are episodic eruptions of solar plasma and magnetic flux tha

63 res per day, and that it is caused either by episodic eruptions that emplace voluminous lava flows or

64 Frost is an important episodic event that damages plant tissues through the fo

65 d glutamate and are postulated to provide an episodic, excitatory drive to gonadotropin-releasing hor

66 aking, it is largely unknown whether and how episodic experiences contribute to value-based decision

67 ore the ability of the ecosystem to tolerate episodic fire and still sequester C.

68 Wood falls provide episodic fluxes of energy to the sea floor that are degr

69 ts undergoing epilepsy monitoring engaged in episodic free recall.

70 ted navigation and planning [12, 14-16], and episodic future thinking more generally [17, 18].

71 d plant migration, yet it has seldom allowed episodic gene exchange of lowland epiphyte lineages such

72 hours include cycles in behavioral arousal, episodic glucocorticoid release, and gene expression.

73 te nuclei, providing homeostatic feedback on episodic GnRH/LH release as well as positive feedback to

74 Intermittent Head Drops are episodic head flexion movements that can occur in a numb

75 st cancer, less is known about the impact of episodic heavy drinking.

76 ses of more than about 10(4) solar masses or episodic hyper-Eddington accretion.

77 Episodic inflows of oxygenated saline water from the Nor

78 ppocampus can combine spatial and contextual/episodic information using a dual coding scheme known as

79 Pregnant rats exposed to episodic inhaled nicotine via a novel lung alveolar regi

80 nsumption (2.09, 1.64-2.67 for high or heavy episodic intake vs never or former drinker; 5.8%, 3.4-9.

81 ntanyl and/or midazolam for the treatment of episodic intracranial hypertension.

82 lthough several detailed mechanisms for such episodic intron generation have been proposed, none has

83 2 and we proposed to designate this locus as Episodic Kinesigenic Dyskinesia (EKD3).

84 Flashes are episodic, lasting approximately 20 s, and may be unitary

85 s systems consolidation dynamics to maintain episodic-like accuracy and hippocampus dependency of rem

86 vation at this remote retention test blocked episodic-like accuracy and induced a general memory impa

87 nce, influences the maintenance of long-term episodic-like accuracy of memory.

88 The retention of episodic-like memory is enhanced, in humans and animals,

89 ith high frequency electrical bursts yielded episodic local enhancements of frequency-specific rhythm

90 cts is not solely due to the use of separate episodic long-term memory systems.

91 mpal-dependent mnemonic functions, including episodic meal-related memories and conditional learned a

92 phy on other CA3-mediated reconstructive and episodic mechanisms, and the role of potential antibody-

93 Our results indicate the episodic memories also reconsolidate, allowing strengthe

94 Episodic memories are gradually assimilated into long-te

95 Episodic memories are information-rich, often multisenso

96 uggest that generalized threat responses and episodic memories are less susceptible to be modified by

97 Because episodic memories are rooted in the space in which they

98 ed during retrieval of integrated multimodal episodic memories compared with unimodal episodic memori

99 analyses revealed that individual multimodal episodic memories could be differentiated in AnG, with c

100 Episodic memories formed during the first postnatal peri

101 Vivid episodic memories in people have been characterized as t

102 Episodic memories initially require rapid synaptic plast

103 pace and time, which can be used to organize episodic memories into networks of related events.

104 odic sampling, decisions are guided by a few episodic memories of past choices.

105 discrepancy in findings leaves it unclear if episodic memories reconsolidate, or only Pavlovian respo

106 new flexibility of threat responses but that episodic memories remain stable.

107 consolidation processes may transform novel episodic memories to reflect such regularities.

108 ork can use memories for specific locations (episodic memories) and statistical patterns of locations

109 mpal area CA1 is essential for consolidating episodic memories, but it is unclear how CA1 activity pa

110 , the inability of adults to recollect early episodic memories, is associated with the rapid forgetti

111 Hippocampal place cells are key to episodic memories.

112 crucial role selectively in the retrieval of episodic memories.

113 dal episodic memories compared with unimodal episodic memories.

114 ucture that is critical for the formation of episodic memories.

115 pples and contribute to the consolidation of episodic memories.

116 rgence reflects an optimal ensemble size for episodic memories.SIGNIFICANCE STATEMENT One primary fac

117 ntrol ( r = .34), working memory ( r = .28), episodic memory ( r = .26), and crystallized IQ ( r = .1

118 g with this dynamic perspective, research on episodic memory (and the hippocampus) has infiltrated do

119 cumab group and -0.93 in the placebo group), episodic memory (change in raw score, -1.53 and -1.53, r

120 , imagining specific future experiences) and episodic memory (i.e., remembering specific past experie

121 episodic memory (p = 0.010), delayed verbal episodic memory (p = 0.007), selective attention (p < 0.

122 nificant improvement in the immediate verbal episodic memory (p = 0.010), delayed verbal episodic mem

123 in immediate (p = 0.045) and delayed verbal episodic memory (p = 0.040) compared to baseline.

124 on effects were also noted in the domains of episodic memory (p=0.03) and motor function (p=0.02).

125 entification (OPID) and the Percepts of Odor Episodic Memory (POEM) tests.

126 with lower scores indicating fewer errors), episodic memory (scores range from 0 to 70, with lower s

127 rises the true "state" of the task), and for episodic memory (where memories are believed to be organ

128 te -0.10 [0.03], p=0.0015) and four domains (episodic memory -0.12 [0.04], p=0.00090; semantic memory

129 on crucial for spatial navigation [6-12] and episodic memory [13-18], has been associated with attrac

130 hat we use semantic memory in the service of episodic memory [2, 3].

131 Normal aging is associated with a decline in episodic memory and also with aggregation of the beta-am

132 inent, both for their vital contributions to episodic memory and for how these same nuclei appear vul

133 nity to investigate the relationship between episodic memory and generalization in parallel.

134 brain region subserving roles of spatial and episodic memory and learning, is sensitive to the detrim

135 er, particularly with tests referable to the episodic memory and motor domains.

136 A greater than expected effect of ageing on episodic memory and motor function with advanced stages

137 ontexts in which these events occurred using episodic memory and support the view that rats may be us

138 irment.SIGNIFICANCE STATEMENT Alterations in episodic memory and the accumulation of Alzheimer's path

139 ogical and conceptual changes in research on episodic memory and the brain.

140 associated inversely with midlife visual and episodic memory and visuospatial associative learning (-

141 findings suggest that the contents of human episodic memory are often constructed in the service of

142 heir relation with cerebral amyloid load and episodic memory as a function of estimated years to symp

143 Neuropsychological tests with MMSE and episodic memory as the primary outcomes and resting-stat

144 availability was positively associated with episodic memory but not with working memory or speed.

145 The hippocampus is thought to contribute to episodic memory by creating, storing, and reactivating p

146 ontextual information to be maintained in an episodic memory circuit.

147 he concurrent context reward value, enabling episodic memory for past experience to support future ad

148 that a reminder can retroactively strengthen episodic memory for Pavlovian threat-conditioned events,

149 nger link between reinforcement learning and episodic memory for rewarding outcomes.

150 essential for the formation and retrieval of episodic memory for which individual hippocampal subfiel

151 The hippocampus is the main locus of episodic memory formation and the neurons there encode t

152 Episodic memory formation depends on information about a

153 Here, we show that human episodic memory formation depends on phase synchrony bet

154 dings provide the first direct evidence that episodic memory formation in humans relies on a theta-sp

155 of experimentally induced theta rhythms and episodic memory formation in humans.

156 rning computational model that accounted for episodic memory formation in single events for group ave

157 Existing accounts of episodic memory function that have focused on explaining

158 esults demonstrate, for the first time, that episodic memory functionally relies on very rapid reacti

159 On this view, episodic memory has a metarepresentational format and sh

160 Episodic memory has been analyzed in a number of differe

161 However, evidence of pathological effects on episodic memory has largely been limited to beta-amyloid

162 medial temporal lobe instigates the loss of episodic memory in Alzheimer's disease, one of the earli

163 match the two primary approaches to studying episodic memory in an unparalleled manner.

164 egions, Abeta, and MTL atrophy contribute to episodic memory in cognitively normal older adults (n =

165 combined evidence indicates that the loss of episodic memory in early Alzheimer's disease reflects mu

166 est whether similar techniques could improve episodic memory in humans, we implemented a microstimula

167 ntifying the effect of the drug on emotional episodic memory in humans.

168 we offer a comprehensive characterization of episodic memory in representational terms, and propose a

169 unt of the metarepresentational structure of episodic memory in terms of its role in communicative in

170 m underlying spatial and temporal aspects of episodic memory in the hippocampus and shed new light on

171 ifying the underlying cellular mechanisms of episodic memory is an important challenge, since this me

172 e data provide neurobiological evidence that episodic memory is not a single construct, challenging t

173 cently learned events.SIGNIFICANCE STATEMENT Episodic memory is often discussed as a solitary constru

174 Episodic memory is thought to critically depend on inter

175 brain networks, but the act of retrieving an episodic memory may place especially heavy demands for c

176 Accuracy of identification and episodic memory of odor percepts differed significantly

177 Selective impairment of episodic memory of odor percepts, relative to identifica

178 essing in the visual cortex led to decreased episodic memory performance specifically for items encod

179 and high genetic risk indirectly influenced episodic memory performance through cortical thickness,

180 medial temporal lobe, which predicted worse episodic memory performance.

181 ith hippocampal volume and activation during episodic memory recall, as measured by blood-oxygen-leve

182 Age-related deficits in episodic memory result, in part, from declines in the in

183 Moreover, converging evidence suggests that episodic memory retrieval involves the reinstatement of

184 Episodic memory retrieval is assumed to rely on the rapi

185 twork segregation-is markedly reduced during episodic memory retrieval relative to closely matched an

186 twork of brain regions have been linked with episodic memory retrieval, but limited progress has been

187 brain is reduced when individuals engage in episodic memory retrieval, relative to other cognitive t

188 he ability to dissociate these components of episodic memory reveals the benefit afforded by measurin

189 ion score 15.4 versus 15.2, p = 0.68; verbal episodic memory score 4.4 versus 4.3, p = 0.79; semantic

190 site scores: beta estimate, -0.11; P = .001; episodic memory scores: beta estimate, -0.18; P < .001;

191 We argue that episodic memory should be understood as a distinctive ep

192 is in 34 participants who performed a verbal episodic memory task while we recorded high gamma (62-10

193 nted electrodes performed spatial and verbal-episodic memory tasks.

194 However, experimental traditions examining episodic memory use very different approaches, and these

195 volumes and cognitive assessment to evaluate episodic memory using the verbal paired associates test.

196 Among temporal lobe subregions, episodic memory was most strongly related to tau-tracer

197 ion especially the primary outcomes MMSE and episodic memory with Bushen capsule treatment.

198 ) and remember episodes from the past (i.e., episodic memory).

199 Episodic memory, a fundamental component of human cognit

200 al role of the medial temporal lobe (MTL) in episodic memory, age-related changes in MTL structure an

201 t with, in part, by endowing RL systems with episodic memory, allowing them to (a) efficiently approx

202 d in formation of spatiotemporal contexts in episodic memory, also represents gradually diverging nar

203 s supporting mesolimbic dopamine activation, episodic memory, and perception.

204 The hippocampus is critical for episodic memory, and synaptic changes induced by long-te

205 t preferentially impact cognitive domains of episodic memory, attention, working memory, verbal seman

206 line SUVR predicted an increasing decline in episodic memory, but other effects on cognition were mor

207 Episodic memory, focused attention, mood, and the percei

208 the early stages of AD is mostly limited to episodic memory, for which the hippocampus has a crucial

209 in a range of cognitive functions, including episodic memory, navigation, and spatial memory.

210 mechanism critical for a major component of episodic memory, opening a new and noncanonical research

211 elve deeply into the structures that mediate episodic memory, particularly the hippocampus, and to tr

212 lded significant SUVR x time interactions in episodic memory, processing speed, vocabulary, and Mini-

213 Older adults experience impairments in episodic memory, ranging from mild to clinically signifi

214 yloid over time (SUVR x time interaction) on episodic memory, reasoning, processing speed, vocabulary

215 y leaves out many aspects of memory, such as episodic memory, related to the traces of individual eve

216 easures of global cognitive function, verbal episodic memory, semantic fluency, and calculation as we

217 n clusters using longitudinal assessments of episodic memory, semantic memory, executive function, an

218 is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stres

219 Across the domains of spatial navigation and episodic memory, the hippocampus is thought to play a cr

220 hile deactivation of either pathway impaired episodic memory, the resulting pattern of mnemonic defic

221 n hippocampus supports functions beyond just episodic memory, with human lesion studies suggesting a

222 mation processing speed, executive function, episodic memory, working memory, and motor function.

223 ge who underwent comprehensive assessment of episodic memory, working memory, and processing speed, a

224 on, including attention, working memory, and episodic memory.

225 ons are critical for episodic simulation and episodic memory.

226 ind that a reminder can renew flexibility of episodic memory.

227 ng of the relationship between pathology and episodic memory.

228 ce cells represent the cellular substrate of episodic memory.

229 n imitate recently encountered actions using episodic memory.

230 e representation of "schemas," in studies of episodic memory.

231 arning and have been assumed to also support episodic memory.

232 ns are one of the core mechanisms underlying episodic memory.

233 ization ability was associated with stronger episodic memory.

234 r sequences of events, a defining feature of episodic memory.

235 the PAI paradigm results in a marked loss of episodic memory.

236 and later recall some of these events using episodic memory.

237 w the two systems interact in the service of episodic memory.

238 on between hippocampal D2DR availability and episodic memory.

239 ept and greater rates of decline on tests of episodic memory.

240 tical for spatial information processing and episodic memory.

241 anterior with reward, social processing, and episodic memory.

242 er animals remember many unique events using episodic memory.

243 are meaningful in the context of real-world episodic memory.

244 eimer's disease, and their relationship with episodic memory.

245 is critical for both episodic simulation and episodic memory.SIGNIFICANCE STATEMENT Humans have the a

246 ablished brain-behaviour relationships (i.e. episodic memory: medial temporal lobe and angular gyrus;

247 retrieval to dissociate three components of episodic memory: retrieval success, precision, and vivid

248 What brain regions underlie retrieval from episodic memory?

249 ccumulation and MTL dysfunction may underlie episodic-memory decline in aging and dementia.

250 s in the medial temporal lobe (MTL) underlie episodic-memory impairments in AD dementia.

251 rhinal cortex, as a substrate of age-related episodic-memory loss.

252 in vivo MTL tau pathology is associated with episodic-memory performance and MTL atrophy in cognitive

253 affected in old age as the best predictor of episodic-memory performance independent of Abeta status.

254 ree unrelated individuals with infancy-onset episodic metabolic crises characterized by encephalopath

255 apy for migraine prevention in patients with episodic migraine and support further investigation of A

256 ated peptide receptor, for the prevention of episodic migraine.

257 ive in reducing the frequency of chronic and episodic migraine.

258 isorders with diverse causes presenting with episodic multisystem symptoms as the result of mast cell

259 not contain such a spike, in part due to the episodic nature of lunar crust or parent body formation.

260 he lower respiratory tract, characterized by episodic or persistent symptoms of wheezing, dyspnea, an

261 ization cause hyperexcitability and familial episodic pain disorder or painful neuropathy, while muta

262 results indicate that the cytopathology and episodic paralysis in our Drosophila EA6 model stem from

263 d with conventional retinotopic mapping with episodic presentation of adjacent stimuli, a continuous,

264 ic specificity induction selectively targets episodic processes that are commonly linked to key core

265 gesting that it arises from autoinoculation, episodic reactivation of latent virus, or both.

266 orted by patients had the characteristics of episodic recollection and included references to particu

267 ingle-shot hippocampal pattern completion to episodic recollection and reveal how oscillatory dynamic

268 phenotypes including anxious depression and episodic recurrence.

269 aso-occlusive crises (VOCs) characterized by episodic, recurrent, and unpredictable episodes of acute

270 er a week, the strength of a memory's unique episodic reinstatement during retrieval was inversely re

271 for a functional, preconscious component of episodic remembering.

272 right frontoparietal network that interrupts episodic retrieval by modulating hippocampal activity; l

273 Classification accuracy during episodic retrieval scaled with the trial-by-trial vividn

274 in humans (males and females) that stopping episodic retrieval to suppress an unpleasant image trigg

275 performance on subsequent tasks that rely on episodic retrieval, including imagining future experienc

276 ole in multimodal feature integration during episodic retrieval, significantly greater AnG activity w

277 reduced modularity is conducive to effective episodic retrieval, which requires close collaboration b

278 en their interaction with one another during episodic retrieval.

279 Here we show that context retrieved during episodic sampling can cause choice behavior to deviate s

280 In episodic sampling, decisions are guided by a few episodi

281 ss1(ARH) neurons play a dual role of driving episodic secretion of GnRH through the differential rele

282 patients can suffer breakthrough pain (BTP), episodic severe pain that "breaks through" the medicatio

283 We propose that such pulses of episodic silicic volcanism would have drastically remode

284 sonance imaging (fMRI) studies indicate that episodic simulation (i.e., imagining specific future exp

285 ses in core network regions are critical for episodic simulation and episodic memory.

286 the left angular gyrus is critical for both episodic simulation and episodic memory.SIGNIFICANCE STA

287 of the left angular gyrus would impair both episodic simulation and memory (16 participants, 10 fema

288 he ability to imagine future episodes (i.e., episodic simulation) and remember episodes from the past

289 ce between both days further emphasizes that episodic sources can substantially impact midday methane

290 These findings provide evidence that an episodic specificity induction selectively targets episo

291 Recent behavioral work suggests that an episodic specificity induction-brief training in recolle

292 mitochondrial disease is Leigh syndrome, an episodic, subacute neurodegeneration that can lead to de

293 report of presentation order effects in the Episodic Temporal Generalization task and demonstrate th

294 The current model of the Episodic Temporal Generalization task, where subjects ha

295 We find that switching from an episodic to a schematic strategy over time leads to enha

296 disorder characterized by hemolytic anemia, episodic vaso-occlusion, and progressive organ damage.

297 effects of sustained haemolytic anaemia and episodic vaso-occlusive events drive the development of

298 the investigated sites are likely due to the episodic ventilation of deep reservoirs rather than warm

299 e province and providing direct evidence for episodic volatile release during the initial stages of C

300 idents occur with alarming frequency and are episodic, with the latest incident, involving the adulte