ライフサイエンスコーパス: epithelia

1 radoxical accumulation of copper (i.e. renal epithelia).

2 ssure to the basolateral surface of alveolar epithelia.

3 lar processes and the material properties of epithelia.

4 terminally truncated ERG protein in prostate epithelia.

5 tablish persistent infection of human airway epithelia.

6 IgR is known to transport IgT and IgM across epithelia.

7 at drive high expression of MuPKS in feather epithelia.

8 s inflammation by targeting GSK3beta in lung epithelia.

9 ucing cells to form a gradient in Drosophila epithelia.

10 days after they project toward non-existing epithelia.

11 ssion at the apical PM in human CF bronchial epithelia.

12 lding, bending and invagination of polarized epithelia.

13 ly up-regulated inMsx1(d/d)/Msx2(d/d)uterine epithelia.

14 a-inflammatory status in the liver and other epithelia.

15 te a defined functional hierarchy within the epithelia.

16 m newborn piglets and ASL on cultured airway epithelia.

17 trolyte transport assays in polarized airway epithelia.

18 del to study interactions between developing epithelia.

19 ed localization within the nuclei of mammary epithelia.

20 regulation and tissue homeostasis of various epithelia.

21 ng PMN-adhesive interactions with intestinal epithelia.

22 alignment responds to cell shape in diverse epithelia.

23 he high permeation of the conjugates through epithelia.

24 apicobasal polarity and natural curvature of epithelia.

25 meability through intestinal mucus layer and epithelia.

26 reted HCO3 (-) at half the rate of wild-type epithelia.

27 fector immune cells to lesion-prone cervical epithelia.

28 making it a more robust system than in other epithelia.

29 ohormone dopamine to promote proteostasis in epithelia.

30 mary CFTRDeltaF508/DeltaF508 human bronchial epithelia.

31 al human lung tissue localized DSP to airway epithelia.

32 ajor intermediate filament network of simple epithelia.

33 s and in well-differentiated human bronchial epithelia.

34 re may be broadly applicable for modeling of epithelia.

35 ells to study physiology and pathogenesis of epithelia.

36 dherin-based junctions to segregate from the epithelia.

37 ired for the removal of unstable proteins in epithelia.

38 ary cultures of human cystic fibrosis airway epithelia.

39 he palatal, buccogingival and ventral tongue epithelia.

40 to be involved in HCO3 (-)transport in other epithelia.

41 eplaced during metamorphosis in both sensory epithelia.

42 dent anion secretion in primary human airway epithelia.

43 e conductance regulator gene to human airway epithelia.

44 y efficient in gene delivery to human airway epithelia.

45 cytes, much is unknown about its function in epithelia.

46 suppress the occurrence of aberrant cells in epithelia.

47 induces various hallmarks of differentiated epithelia.

48 t for normal CFTR channel function in airway epithelia.

49 iginating in stratified and pseudostratified epithelia.

50 l confinement similar to that experienced in epithelia.

51 how homeostasis is achieved in regenerating epithelia.

52 differentiation to give rise to all nephron epithelia.

53 minal differentiation in stratified squamous epithelia.

54 o differentiate into hepatocytes and biliary epithelia.

55 the global contractility or extensibility of epithelia.

56 ich differentiate in situ within lung airway epithelia.

57 alize to the basolateral domain in polarized epithelia.

58 l specimens using reconstituted human airway epithelia.

59 tion by phosphorylation, compared to control epithelia.

60 tory cells and reduced transport across lung epithelia.

61 beta-induced IL-8 secretion in CF bronchial epithelia.

62 ensory receptors of the mammalian vestibular epithelia.

63 romises the self-renewal capacity of mammary epithelia.

64 cell junction area at the apical surface of epithelia.

65 ressed in terminally differentiating sensory epithelia.

66 ovirus, AAV2, in differentiated human airway epithelia.

67 ortunities to harness the innate immunity of epithelia against infection.

68 chemic NF-kappaB activation in renal tubular epithelia aggravates tubular injury and exacerbates a ma

69 opose that mitotic cell rounding in columnar epithelia allows cells to properly interpret cortical cu

70 Rap1 activity by PlexA in damaged Drosophila epithelia allows epithelial remodelling, thus facilitati

71 mouse WNT10A mutant palmoplantar and tongue epithelia also display specific differentiation defects

72 In epithelia, an increased CFTR activity may correspond to

73 sformed human cells, normal mouse intestinal epithelia and adenomas, human cancer cell lines with or

74 was localized apically in human bronchiolar epithelia and basolaterally in the reabsorptive duct of

75 ions (TJs) are barrier forming structures of epithelia and can be described as tightly sealed interce

76 e at the apical plasma membrane of secretory epithelia and cause cystic fibrosis (CF) with variable d

77 in which p53 deletion is targeted to biliary epithelia and CC induced using the hepatocarcinogen thio

78 rect Foxn1 target genes for postnatal thymic epithelia and defined the Foxn1 binding motif.

79 initial stage of tumorigenesis in Drosophila epithelia and discuss comparable mechanisms in mammalian

80 This observation extended to intact epithelia and disruption of the actin cytoskeleton preve

81 analyzed how Mena11a, an isoform enriched in epithelia and epithelial-like cells, affects Mena-depend

82 We quantified cell death in all olfactory epithelia and found massive cell death in the PC and the

83 d tumor appearance in Apc-mutated intestinal epithelia and greatly prolonged mice survival without af

84 es that may degrade DeltaF508-CFTR in airway epithelia and identifies a new role for NEDD8 in regulat

85 spread NF-kappaB activation in renal tubular epithelia and in interstitial cells that peaked 2-3 days

86 miR-200 family members in oral and tonsillar epithelia and in saliva.

87 ates multiciliogenesis in both murine airway epithelia and in Xenopus laevis epidermis.

88 ansient wave, which preferentially populates epithelia and lung as well as gut-associated lymphoid ti

89 ms leading to barrier function in stratified epithelia and may facilitate the development of future t

90 oscale pipet to precisely locate tTJs within epithelia and measure the apparent local conductance of

91 xpressed in glomerular podocytes and tubular epithelia and metabolizes angiotensin II (AngII), a pept

92 In wing epithelia and muscle, Nin localizes to noncentrosomal mi

93 Caenorhabditis elegans oocytes to vertebrate epithelia and neurons.

94 lishing and maintaining membrane polarity in epithelia and other polarized cells.

95 f the biological effects of LCs on pulmonary epithelia and our observations strongly suggest that LCs

96 on of smooth muscle cells surrounding airway epithelia and promote airway differentiation of epitheli

97 In other types of squamous epithelia and squamous cell carcinomas, a similar contro

98 ut the cells of origin for these metaplastic epithelia and subsequent malignancies remain unknown.

99 ecular interactions between PMNs and mucosal epithelia and the associated functional consequences.

100 n, due to the short distance in reaching the epithelia and the high permeation of the conjugates thro

101 er ear - the vestibular and cochlear sensory epithelia and the spiral ganglion - by measuring electro

102 apoptosis, migration, and adhesion in the PS epithelia and underlying mesenchyme.

103 retically study longitudinal folds in simple epithelia and we identify four types of corrugated morph

104 eome with other IE subproteomes from sensory epithelia and whole IE.

105 s talk of innate lymphoid cells with damaged epithelia and with the recipient microbiome, the impact

106 r basal body docking in otic vesicle sensory epithelia and, surprisingly, short cilia form in mechano

107 le excitability, electrolyte movement across epithelia, and acidification of intracellular organelles

108 mmation in the mouth, retina, kidneys or gut epithelia, and circulating cytokine levels.

109 results confirm the active nematic nature of epithelia, and demonstrate that defect-induced isotropic

110 MICA is selectively expressed within epithelia, and is the major ligand for the activatory re

111 s is essential for the function of different epithelia, and its failure results in brain defects, res

112 ite proteins in human multiciliated tracheal epithelia, and its loss inhibits motile ciliogenesis.

113 expressed in adult tissue stem cells of many epithelia, and its overexpression is negatively correlat

114 apillomaviruses infect mucosal and cutaneous epithelia, and the high-risk HPV types account for 5% of

115 in elevated removal of unstable proteins in epithelia, and this enhancement requires DA signaling.

116 In the Drosophila ventral furrow and other epithelia, apical constriction of hundreds of epithelial

117 In epithelia, apical-basal polarity often coexists, and som

118 Epigenetic marks in respiratory epithelia are associated with allergic asthma and gene e

119 Here, we show that the anemone's epithelia are colonized by diverse bacterial communities

120 AI-2 mimic activity is induced when epithelia are directly or indirectly exposed to bacteria

121 ng bacterial colonization on mucosal barrier epithelia are hypochlorous acid (HOCl), hypobromous acid

122 n polarized/well-differentiated human airway epithelia are infected with HBoV1 in vitro, they develop

123 The airway epithelia are lined with fluid called airway surface liq

124 Epithelia are modelled using a rheological law that rela

125 g regulation of PMN migration across mucosal epithelia are poorly understood.

126 s been demonstrated in mice that LC-deprived epithelia are rapidly replenished by short half-life lan

127 clinical disease, highlighting the spread to epithelia as an attractive target for therapeutic strate

128 secretion, these channels are found in other epithelia as well as nonepithelial tissues.

129 y investigating the effect of AMPs on airway-epithelia associated genes upon administration to infect

130 predominant SENP transcript in human mammary epithelia but is significantly reduced in precancerous d

131 etion of Sox17 in the primordial gallbladder epithelia but not in fetal liver hepatoblasts.

132 (+) (BK) current was demonstrated in control epithelia but was not stimulated in epithelia differenti

133 echanisms underlying extrusion of cells from epithelia, but far less is known of the converse mechani

134 that is particularly rare in human bronchial epithelia, but not in other human tissues, suggesting ti

135 d in luminal and suprabasal cells of several epithelia, but suppressed in p63+ basal cells.

136 ERG is not expressed in normal prostate epithelia, but when expressed, it promotes tumorigenesis

137 of mouse models for studying a wide range of epithelia by providing highly enriched populations of di

138 st time that virus infection of human airway epithelia can also induce pyroptosis.

139 cells within it that resemble ocular-surface epithelia can be isolated by pipetting and FACS sorting

140 We show that mucociliary membranes of animal epithelia can create fluid-mechanical microenvironments

141 red that Cre-Lox ablation of Rac1 in mammary epithelia causes gross enlargement of the epithelial tre

142 sed in NSCLC cells compared with normal lung epithelia cells.

143 Likewise, heterozygous epithelia (CFTR(+/-) or CFTR(+/F508)) expressed CFTR and

144 rophysiological tests show strong effects in epithelia, close to those of natural anion channels.

145 activation of the JAK/STAT3 pathway in tumor epithelia concomitant with proliferation.

146 Inner ear sensory epithelia contain mechanosensitive hair cells that trans

147 Skin and mucosal epithelia deploy antimicrobial peptides (AMPs) to elimin

148 ransport in differentiated, pseudostratified epithelia derived from normal human bronchial basal cell

149 activated form of IKKbeta in the esophageal epithelia develop esophageal disorders.

150 By contrast, columnar epithelia differentiate an apical domain that recruits C

151 control epithelia but was not stimulated in epithelia differentiated in the absence of HC (HC0).

152 udy shows that, upon stretching or wounding, epithelia display a fast proliferative response that all

153 Basal cells in pseudostratified epithelia display a single long cytoplasmic process that

154 suggests a possible role for FXYD5 in normal epithelia during inflammation.

155 1/2 complex and thus the dynamic behavior of epithelia during lip/palate development.

156 contribute to tissue morphogenesis, but how epithelia dynamically remodel their BMs is unknown.

157 The reported data demonstrate that in skin epithelia, EED, Suz12, and Ezh1/2 function largely as su

158 We conclude that metaphase spindles in epithelia engage in a stereotyped "dance," that this dan

159 In vitro- and in vivo-polarised absorptive epithelia (enterocytes) are considered to be non-phagocy

160 EC) mice exhibited grossly normal intestinal epithelia, except for a defect in Paneth cell granules.

161 ion had a dramatic effect; cells cultured as epithelia exhibited much greater binding than cells in s

162 Correspondingly, cystic epithelia express higher levels of integrins (ECM recept

163 Airway epithelia express sialylated receptors that recognize ex

164 Moreover, HC0 epithelia expressed significantly more KCNMA1 containing

165 Rather, epithelia flexibly polarize Rab distribution, producing

166 Epidermal barrier epithelia form a first line of defense against the envir

167 PC1) or polycystin-2 (PC2), in which tubular epithelia form fluid-filled cysts.

168 We detected alterations in airway epithelia from 22 patients, with an increased frequency

169 differences were observed in cultured airway epithelia from CF and non-CF pigs exposed to the stimulu

170 Well-characterized mPV sera bind mucosal epithelia from the hDsg3 mice, but not mucosal tissues f

171 ement membranes that separate endothelia and epithelia from the underlying tissue.

172 Epithelia function as barriers against environmental ins

173 Within mammary epithelia, Gal-1 localized within nuclear Gemini bodies

174 Lgr5(+) progenitor cells from the sensory epithelia gave rise to hair cell-like cells, but not neu

175 spontaneously formed topological defects in epithelia govern cell fate.

176 Epithelia grow and undergo extensive rearrangements to a

177 cts well-differentiated primary human airway epithelia (HAE) in vitro In human embryonic kidney HEK29

178 surface of well-differentiated human airway epithelia (HAE).

179 teins and the filaments they form in surface epithelia has long been appreciated.

180 ectively achieve multifunctionality, mucosal epithelia have evolved unique microenvironments that cre

181 ated after the epidermis and digestive tract epithelia have matured, ensuring that both organs can wi

182 11021 directly activated channels in control epithelia; however, under HC0 conditions, activation onl

183 uild its entire body from a portion of adult epithelia in a continuous and stereotyped process called

184 ths of colonization in colon macrophages and epithelia in areas of inflammation.

185 xonal pathfinding, in the healing of damaged epithelia in Drosophila.

186 d to neutrophils migrating across intestinal epithelia in response to a chemoattractant.

187 elial Na(+) channel (ENaC) in salt-absorbing epithelia in the kidney, lung, and other tissues.

188 h the appearance of ectopic cystic duct-like epithelia in their gallbladders.

189 We conclude that cultured gill epithelia in vitro provide a powerful approach to studyi

190 opes, induces branching migration of mammary epithelia in vivo, ex vivo, and in 3D organotypic cultur

191 ion of Wnt pathway genes in intestinal crypt epithelia, including crypt base columnar stem cells and

192 cells in primary crude cultures of multiple epithelia, including the cornea, oral and lingual epithe

193 nderlying disease progression on all mucosal epithelia, including those in the mouth, lungs, and gut.

194 In air-exposed airway epithelia, induction of factors required for multiciliog

195 is the first report of pyroptosis in airway epithelia infected by a respiratory virus.IMPORTANCE Mic

196 hypothesis that aPKC has a dual function in epithelia, inhibiting the NF-kappaB pathway in addition

197 Cells in the fusing epithelia intercalate and are removed, creating a canal.

198 that migration of neutrophils across mucosal epithelia is associated with disease symptoms and disrup

199 eratinocytes on the surface of skin and oral epithelia is associated with the degradation of nuclear

200 s known about how development of these three epithelia is coordinated temporally.

201 butes to the homeostasis of adult stratified epithelia is currently unknown.

202 A model of neutrophil migration across epithelia is desirable to interrogate the underlying mec

203 dicating that expression in immune cells and epithelia is divided among families.

204 Functional modeling of many adult epithelia is limited by the difficulty in maintaining re

205 signaling cascades, LC8's role in developing epithelia is poorly understood.

206 sence of apical TGF-beta signaling in normal epithelia is primarily a reflection of domain-specific r

207 Given that PMN migration across mucosal epithelia is strongly correlated with disease symptoms i

208 hat sustained activation of EGFR in proximal epithelia is sufficient to cause spontaneous, progressiv

209 the basolateral membrane of proximal-tubule epithelia is the most probable cause of pRTA in this cas

210 e most obvious manifestations of polarity in epithelia is the subdivision of the cell surface by cell

211 r tissues; how MASPs are activated in mature epithelia is unknown.

212 Hair cells differentiate only in sensory epithelia known or proposed to have a lineage relationsh

213 re glomeruli, and the renal proximal tubular epithelia lacked proper localization of adhesion complex

214 ly rescued the polarity defects in embryonic epithelia lacking the polarity proteins Stardust and Cru

215 ctivates expression of Cre in the esophageal epithelia, leading to expression of a constitutively act

216 Generation of a barrier in multi-layered epithelia like the epidermis requires restricted positio

217 mast cells, present in stroma of both airway epithelia, lung as well as in other organs.

218 us, intercellular Ca(2+) waves in developing epithelia may be a consequence of stress dissipation dur

219 tly as entotic hosts, suggesting that normal epithelia may engulf and kill aberrantly dividing neighb

220 n, the epigenetic alterations in respiratory epithelia might provide insight into allergic asthma.

221 We have studied the role of spectrins during epithelia morphogenesis using the Drosophila follicular

222 creating an SC signature for normal colonic epithelia (NCE).

223 , such as immunosuppression, invasion of the epithelia occurs.

224 thma-associated methylation changes in nasal epithelia of adult white asthmatic patients.

225 TA4 was strongly expressed in the neoplastic epithelia of invasive carcinomas.

226 lly acquired molecular alterations in airway epithelia of lung cancer patients has remained unknown.

227 In proliferating epithelia of mammalian skin, cells of irregular polygon-

228 sis, causes cytopathology in the respiratory epithelia of mammals and robustly triggers the Drosophil

229 tive activation of IKKbeta in the esophageal epithelia of mice leads to inflammation and angiogenesis

230 sponses specifically in brain endothelia and epithelia of mice.

231 ells from the utricular and cochlear sensory epithelia of newborn mice to circumvent this challenge.

232 tem examination with the CDV FAT on external epithelia of recently vaccinated, sick dogs is a clinica

233 in the basal skin epidermis and the mucosal epithelia of the digestive tract (K14 HPV49 E6/E7-Tg mic

234 e, we genetically ablated Stat3 in the tumor epithelia of the inducible PyVmT mammary tumor model and

235 increase in neutrophil tracking in tracheal epithelia of the treatment calves compared to control an

236 gulates chloride transport, expressed in the epithelia of various organs.

237 ially infect the cutaneous and mucocutaneous epithelia of vertebrates.

238 While virus-infected airway epithelia often activate NLRP3 inflammasomes, studies to

239 the patterns were lost inMsx1(d/d)/Msx2(d/d)epithelia on d 5, suggesting important roles during impl

240 , while no expression was observed in airway epithelia or lung.

241 gill cells, either as cultured reconstructed epithelia, or dispersed in suspension.

242 hat the third and fourth ventricle E2 and E3 epithelia originate from the anterior floor plate.

243 cell lines derived from the ovarian surface epithelia (OSE) of mice with conditional mutations in Kr

244 cystic fibrosis (DeltaF508/DeltaF508) airway epithelia partially restored DeltaF508-cystic fibrosis t

245 Virus antigen was observed in airway epithelia, pneumocytes, and macrophages.

246 We show that mammalian epithelia produce an AI-2 mimic activity in response to

247 a, the predominant C-terminal p63 variant in epithelia, promotes the transcriptional activity of TAp6

248 Oral epithelia protect against constant challenges by bacteri

249 of the immune system that reside in barrier epithelia provide a first line of defense against pathog

250 , many of the mechanisms that repair damaged epithelia remain poorly characterized.

251 Epithelial tissues (epithelia) remove excess cells through extrusion, preven

252 elia, including the cornea, oral and lingual epithelia, salivary gland, esophagus, thymus, and bladde

253 cts only in the ectopic layers of stratified epithelia, similar to integrin mutants.

254 patches of apical cell contractility, model epithelia smoothly deform into invaginated or evaginated

255 In stratified epithelia such as the cornea and skin, healing occurs in

256 d in IPF lung and concentrated in the airway epithelia, suggesting a potential role for DSP in the pa

257 6983 blocked BK activation by UTP in control epithelia, suggesting that PKC-mediated phosphorylation

258 RAGE exhibits an extended life span in lung epithelia (t(1/2) 6 h), is monoubiquitinated at K374, an

259 strong ASC expression in the skin and other epithelia that act as barriers to insult.

260 1 (HSV-1) infects humans through stratified epithelia that are composed primarily of keratinocytes.

261 evelop into inner ear organoids with sensory epithelia that are innervated by sensory neurons.

262 preparations develop electrically tight gill epithelia that can withstand freshwater on the apical ce

263 n and water homeostasis across membranes and epithelia that exacerbate the initial effects of chillin

264 nes (nTSGs) in Drosophila wing imaginal disc epithelia that tumor initiation depends on tissue-intrin

265 cells of Barrett's, gastric and oesophageal epithelia that yield divergent tumour types following in

266 In the vestibular sensory epithelia, the virus transduced large numbers of hair ce

267 pithelial-myofibroblast transition in intact epithelia; the other prerequisite is the uncoupling of i

268 o originate from simple or pseudo-stratified epithelia through activation of quiescent cells and/or a

269 e for basolateral Ca(2+) efflux in the renal epithelia, thus contributing to renal Ca(2+) reabsorptio

270 ial feeding source, also signal to frontline epithelia to activate the xenobiotic stress response so

271 grins are required for the ability of breast epithelia to do what they are programmed to do, which is

272 al coherence of cell layers is essential for epithelia to function as tissue barriers and to control

273 ell membrane receptor serving to anchor lung epithelia to matrix components, and it also amplifies in

274 IgR) transports polymeric IgA and IgM across epithelia to mucosal secretions, where the cleaved ectod

275 ning diverse cell types, ranging from simple epithelia to neurons and motile immune cells [1-3].

276 ow that Rac1 is crucial for mammary alveolar epithelia to switch from secretion to a phagocytic mode

277 eptor (pIgR) transports polymeric Abs across epithelia to the mucosa, where proteolytic cleavage rele

278 regional immunity are known in other mucosal epithelia, to date, no immune microenvironments have bee

279 Here we show that in Drosophila epithelia, tricellular junctions (TCJs) localize force g

280 ed increased DPP4 immunostaining in alveolar epithelia (type I and II cells) and alveolar macrophages

281 ed that aPKC is down-regulated in intestinal epithelia under inflammatory stimulation.

282 Hence, a conserved mechanism emerges whereby epithelia use organ-specific BTNL/Btnl genes to shape lo

283 expressed widely mammalian cells, including epithelia, vascular smooth muscle tissue, electrically e

284 microscopy of immunostained cochlear sensory epithelia, was coupled with a corresponding functional r

285 ssed between blastogenic vs. non-blastogenic epithelia we compared three different mapping and analys

286 By experimentally stretching epithelia, we find that mechanical stretch itself rapidl

287 o from explants of embryonic mouse olfactory epithelia, we observed that axons dynamically interact w

288 del system for the study of pseudostratified epithelia, we report here the surprising discovery that

289 ite of blastogenesis onset and from the same epithelia where this process is never triggered.

290 barriers formed at the corners of polarized epithelia where tight junctions in vertebrates or septat

291 ly in the cytoplasm of epidermal and foregut epithelia, where it forms belt-like filaments around eac

292 e kidney proximal tubule and collecting duct epithelia, where it has an important role in amino acid

293 the apical plasma membrane (PM) of secretory epithelia, which is attributed to the degradation of the

294 iviral interferon-stimulated genes (ISGs) in epithelia, while the effect of IFN-lambda in non-epithel

295 ce mechanical resistance of all neighbouring epithelia will feedback on individual cells.

296 Epithelia with a 50:50 mix secreted HCO3 (-) at half the

297 multicellular organisms critically requires epithelia with extracellular diffusion barriers.

298 individual adherens junctions (AJs) provide epithelia with the fluidity required to maintain tissue

299 Therefore, we generated porcine airway epithelia with varying ratios of CF and wild-type cells.

300 alin defines the apical recycling pathway of epithelia, with CRE as its apical sorting station.