ライフサイエンスコーパス: epoxidase

1 rived metabolites that were dependent on the epoxidase.

2 e overexpressed and purified the desired HPP epoxidase.

3 strate, the enzyme is converted to an active epoxidase.

4 between OsONS1 and both O. spinosa squalene epoxidases.

5 yrans can be initiated by post-assembly line epoxidases.

6 op codon mutation in Sqle, encoding squalene epoxidase, a rate-limiting enzyme in cholesterol biosynt

7 enzymes, hexokinase 1 (HXK1) and zeaxanthin epoxidase (ABA1), by transcriptional control.

8 maleimide inhibited both the carboxylase and epoxidase activities of the enzyme.

9 The vitamin K epoxidase activities of these mutants were reduced in pa

10 he two-chain carboxylase had carboxylase and epoxidase activities similar to those of one-chain carbo

11 lase, the His to Ala mutants all showed full epoxidase activity but K218A activity was not detectable

12 rbate availability can limit violaxanthin de-epoxidase activity in vivo, leading to a lower NPQ.

13 Epoxidase activity is induced by Phe-Leu-Glu-Glu-Leu (FL

14 ng the ets1-1 allele have decreased squalene epoxidase activity, while those containing the ets2-1 al

15 (dry2) mutant that shows decreased squalene epoxidase activity.

16 gnificant vitamin K-dependent carboxylase or epoxidase activity.

17 carboxylase activity and vitamin K-dependent epoxidase activity.

18 ning substrate, carboxylase has little or no epoxidase activity.

19 ectal cancer cell lines highlighted squalene epoxidase, an oxygen-requiring enzyme in cholesterol bio

20 Using purified epoxidase and (18)O isotopic labeled HPP, the retention

21 Therefore, this protein is indeed a true HPP epoxidase and is termed Ps-HppE.

22 The association of violaxanthin de-epoxidase and monogalactosyldiacyglyceride at pH 5.2 is

23 Violaxanthin de-epoxidase and zeaxanthin epoxidase catalyze the addition

24 Sequence analyses of both violaxanthin de-epoxidase and zeaxanthin epoxidase establish the xanthop

25 ibitors terbinafine (TBF, targeting squalene epoxidase) and itraconazole (ITZ, targeting lanosterol C

26 aryl-coenzyme A (HMG-CoA) synthase, squalene epoxidase, and acyl-CoA:cholesterol acyltransferase (ACA

27 vel metabolites, identification of the 10,11-epoxidase, and full characterization of the mupirocin bi

28 t loss of function of DDB1, DET1, Zeaxanthin Epoxidase, and Ip up-regulates CHRC levels.

29 s-related protein1 (LHCSR1), violaxanthin de-epoxidase, and PSII subunit S, remained stable.

30 he non-heme diiron enzyme benzoyl coenzyme A epoxidase, BoxB.

31 In contrast, the Leptospira ortholog showed epoxidase but not detectable carboxylase activity and di

32 ed to provide further insights into the P450 epoxidase catalytic efficiency affected by substrate str

33 Violaxanthin de-epoxidase and zeaxanthin epoxidase catalyze the addition and removal of epoxide g

34 Violaxanthin de-epoxidase catalyzes the de-epoxidation of violaxanthin t

35 ructure of the N-terminally histidine-tagged epoxidase component of this system, NSMOA, determined to

36 Squalene epoxidase converts squalene into oxidosqualene, the prec

37 as amino levulinate synthase 1 and squalene epoxidase displayed CAR-independent induction by PB.

38 ed in wild-type cells or cells with squalene epoxidase down-regulated.

39 A P450 epoxidase encoded by c rpE recently identified from the

40 values for the epoxide and a stereospecific epoxidase enzyme has been proposed to account for this d

41 is dependent on the dosage of the zeaxanthin epoxidase enzyme.

42 oth violaxanthin de-epoxidase and zeaxanthin epoxidase establish the xanthophyll cycle enzymes as mem

43 sion is required to regulate violaxanthin de-epoxidase expression and to support photosynthetic activ

44 A similar reduction in squalene epoxidase expression was also observed in Egr1 null mice

45 Two new sequences for violaxanthin de-epoxidase from tobacco and Arabidopsis are described.

46 fferent physical positions in the zeaxanthin epoxidase gene (ABSCISIC ACID DEFICIENT 1/ZEAXANTHIN EPO

47 The epoxidase gene was dispensable in a nematode-infective j

48 ons in the coding sequence of the zeaxanthin epoxidase gene, resulting in the constitutive accumulati

49 ants are new alleles of aba1, the zeaxanthin epoxidase gene.

50 Previously, violaxanthin de-epoxidase had been partially purified.

51 Violaxanthin de-epoxidase has an isoelectric point of 5.4 and an apparen

52 ment1 [hp1]), Deetiolated1 (hp2), Zeaxanthin Epoxidase (hp3), and Intense pigment (Ip; gene product u

53 The iron-dependent epoxidase HppE converts (S)-2-hydroxypropyl-1-phosphonat

54 (S)-2-Hydroxypropylphosphonic acid epoxidase (HppE) catalyzes the epoxide ring closure of (

55 (S)-2-Hydroxypropylphosphonic acid [(S)-HPP] epoxidase (HppE) is a mononuclear iron enzyme that catal

56 (S)-2-hydroxypropylphosphonate ((S)-2-HPP) epoxidase (HppE) is a mononuclear non-haem-iron-dependen

57 (S)-2-Hydroxypropylphosphonic acid epoxidase (HppE) is an O2-dependent, nonheme Fe(II)-cont

58 (S)-2-Hydroxypropylphosphonic acid epoxidase (HppE) is an unusual mononuclear iron enzyme t

59 Hydroxypropylphosphonic acid epoxidase (HppE) is an unusual mononuclear iron enzyme t

60 )-2-hydroxypropylphosphonic acid ((S)-2-HPP) epoxidase (HppE) is an unusual mononuclear non-heme iron

61 (TauD), (S)-(2)-hydroxypropylphosphonic acid epoxidase (HppE), and 1-aminocyclopropyl-1-carboxylic ac

62 ylphosphonic acid (HPP) to fosfomycin by HPP epoxidase (HppE), which is a mononuclear non-heme iron-d

63 pid synthesis (fatty acid synthase, squalene epoxidase, hydroxy-methylglutaryl coenzyme A reductase),

64 script and protein levels of violaxanthin de-epoxidase in the eIFiso4G loss of function mutant and an

65 xpression of monCI, encoding a flavin-linked epoxidase, in S. coelicolor was shown to significantly i

66 idual endogenous synthesis with the squalene epoxidase inhibitor NB-598 prevented growth in beta-sito

67 In contrast, HPP epoxidase is alpha-ketoglutarate independent.

68 tial biochemical evidence revealing that HPP epoxidase is an iron-dependent enzyme and that both NAD(

69 k data base and suggest that violaxanthin de-epoxidase is nuclear encoded, similar to other chloropla

70 ion reaction of hydroxypropylphosphonic acid epoxidase may occur.

71 in reductase (SMOB) and FAD-specific styrene epoxidase (NSMOA).

72 e gene (ABSCISIC ACID DEFICIENT 1/ZEAXANTHIN EPOXIDASE, or ABA1/ZEP) in TG01 and TG10.

73 s with either of the two O. spinosa squalene epoxidases, OsSQE1 or OsSQE2, alpha-onocerin production

74 duction was boosted, most likely because the epoxidases produce higher amounts of squalene-2,3;22,23-

75 tion of the bifunctional C-methyltransferase/epoxidase PsoF to complete the trans to cis isomerizatio

76 um of oxidized iron-reconstituted fosfomycin epoxidase reveals resonances typical of S = (5)/(2) Fe(I

77 formation: squalene synthase (SS), squalene epoxidase (SE), and beta-amyrin synthase (beta-AS).

78 Glu substrate is present, the Leptospira VKD epoxidase showed unfettered epoxidation in the absence o

79 identified six putative Arabidopsis squalene epoxidase (SQE) enzymes and used heterologous expression

80 of the erg26 mutation into an erg1 (squalene epoxidase) strain also was viable in ergosterol-suppleme

81 by ( S)-2-hydroxypropylphosphonic acid (HPP) epoxidase ( Sw-HppE).

82 ight polyketide synthase modules, and a P450 epoxidase that converts desoxyepothilone into epothilone

83 LOS6/ABA1 encodes a zeaxanthin epoxidase that functions in ABA biosynthesis.

84 KD carboxylase is bifunctional, acting as an epoxidase that oxygenates vitamin K to a strong base and

85 uggests that CVDE evolved from an ancient de-epoxidase that was present in the common ancestor of gre

86 that, in contrast to dicots, root zeaxanthin epoxidase transcripts were unchanged.

87 e for the synthesis of mogroside V: squalene epoxidases, triterpenoid synthases, epoxide hydrolases,

88 port a detailed characterization of the CrpE epoxidase using an engineered maltose binding protein (M

89 transthylakoid delta pH and violaxanthin de-epoxidase (VDE) activity.

90 Violaxanthin de-epoxidase (VDE) is a lumen-localized enzyme that catalyz

91 Violaxanthin de-epoxidase (VDE) is the key enzyme responsible for zeaxan

92 our beta-carotene hydroxylase and zeaxanthin epoxidase were ranked first and forty-fourth respectivel

93 iolaxanthin to zeaxanthin is violaxanthin de-epoxidase, which is located in the thylakoid lumen, is a

94 Among these is hydroxypropylphosphonic acid epoxidase, which represents a new subfamily of non-haem

95 ity of terbinafine, an inhibitor of squalene epoxidase within the sterol biosynthesis pathway, but ha

96 ding the ABA biosynthetic enzymes zeaxanthin epoxidase (ZEP) and 9-cis-epoxycarotenoid dioxygenase (N

97 acid (ABA) biosynthesis pathway, zeaxanthin epoxidase (ZEP) and 9-cis-epoxycarotenoid dioxygenase (N

98 Since zeaxanthin epoxidase (ZEP) depletes the carotenoid pool in subseque

99 ZEAXANTHIN EPOXIDASE (ZEP) was the major contributor to carotenoid