ライフサイエンスコーパス: epoxide

1 ith good leaving groups (e.g. vinyl chloride epoxide).

2 of an inverse rate order with respect to the epoxide.

3 e treated with epibromohydrin (EBH), a model epoxide.

4 e preferentially opens cyclic anhydride over epoxide.

5 a simple oxyanion that is generated from an epoxide.

6 lysis in cycloaddition reactions of CO2 with epoxides.

7 r efficiently catalyzing the methanolysis of epoxides.

8 ite IRA 400 HO(-) to yield the series 1 diol epoxides.

9 l is less than that of the starting chalcone epoxides.

10 ining polyethers from di- and trisubstituted epoxides.

11 s with mCPBA gave the isomeric series 2 diol epoxides.

12 selective carbonylation of cis-disubstituted epoxides.

13 he occurrence of acid-catalyzed reactions of epoxides.

14 ("aCifR") and is induced in the presence of epoxides.

15 lective alkene cross metatheses of cis-vinyl epoxides.

16 ers are prepared from a pivotal intermediate epoxide 12.

17 We show that one of these analogues, CDDO-epoxide (13), is comparable to 4 in terms of cytotoxicit

18 unced actions were observed with the omega-6 epoxide, 14,15-EET, and nonoxidized DHA.

19 lammation studies revealed that the terminal epoxides 17,18-EEQ-EA and 19,20-EDP-EA dose-dependently

20 Furthermore the omega-3 endocannabinoid epoxides 17,18-EEQ-EA and 19,20-EDP-EA exerted antiangio

21 n and abundant levels of the omega-3-derived epoxides 17,18-epoxyeicosatetraenoic acid (17,18-EEQ) an

22 Cholesterol-5,6-epoxide (5,6-EC) metabolism is deregulated in BC but the

23 t of the approach entailed treatment of iodo-epoxide 7, prepared by N-alkylation of 6 with (S)-glycid

24 eriments and on an experiment with CBZ-10,11-epoxide a transformation pathway of CBZ in intact tomato

25 efins containing an alcohol, an aldehyde, an epoxide, a carboxylic acid, or an alkenyl group may be u

26 ocerebrosidase inhibition by conduritol beta-epoxide, a cellular model of Gaucher disease.

27 dependence of the polymerization rate on the epoxide, a zero-order dependence on the cyclic anhydride

28 with fluorescent beta-aziridine but not beta-epoxide ABPs identifies the acid/base residue in mutagen

29 Whereas beta-epoxide ABPs require a protonated acid/base for irrevers

30 The quantitative isolation of the epoxides, accomplished by solvent precipitation of triet

31 lyst, Hf-NU-1000 is also efficient for other epoxide activations, leading to the regioselective and e

32 enzoic acids with both terminal and internal epoxides affords 3,4-dihydroisocoumarins in one step.

33 eroxides, hydroxy-dienes and other alcohols, epoxides, aldehydes and keto-dienes, was followed by (1)

34 ction of key intermediates such as alcohols, epoxides, aldehydes, ketones and organic acids, but also

35 Mono-(2,3-manno-epoxide) alpha-, beta-, and gamma-CDs were subsequently

36 he related benzannulation transformations of epoxide and acetal derivatives.

37 odinuclear catalysts have good precedent for epoxide and carbon dioxide/anhydride copolymerizations;

38 tic counterpart synthesized from enantiopure epoxide and catalyst is semicrystalline with a T(m) (mel

39 ass of compounds in diet-induced obesity-C18 epoxide and diol oxylipins.

40 argeting the enzymes involved in cholesterol epoxide and glucocorticoid metabolism or GR may be novel

41 Reactivities of epoxide and ketone functional groups on the cycloheptane

42 The second capsule contains a difunctional epoxide and reactive diluent.

43 eds in a kinetic resolution, furnishing both epoxide and thiirane in high yields and enantiomeric pur

44 y oxidation products such as some aldehydes, epoxides and alcohols.

45 ains having also hydroperoxy/hydroxy groups, epoxides and aldehydes); the formation of hydroxides was

46 e stereoselective union of readily available epoxides and allyl electrophiles is disclosed.

47 Using the cycloaddition of the epoxides and CO2 as a model reaction, dramatic activity

48 through the alternating copolymerization of epoxides and cyclic anhydrides compose a growing class o

49 he copolymerization of a variety of terminal epoxides and cyclic anhydrides.

50 Epoxides and diepoxides were clearly identified from bet

51 As the role of epoxides and diols in angiogenesis is unclear, we compar

52 (IEG+) strategy that begins with enantiopure epoxides and facilitates the efficient synthesis of a fa

53 ctivity (up to s = 93), giving the unreacted epoxides and the corresponding protected 1,2-diols in hi

54 n of gamma-hexachlorocyclohexane, heptachlor-epoxide, and alpha- and beta-endosulfan (-0.02 to -33 ng

55 diol is converted into either a trans or cis epoxide, and these are subsequently converted into (+)-a

56 ion is converted into either a trans- or cis-epoxide, and these are subsequently converted to (+)-ant

57 he reactions of alpha-lithiated haloalkanes, epoxides, and carbamates.

58 ne was the Lewis acid chosen to activate the epoxides, and onium halides or onium alkoxides involving

59 The resultant allylic epoxides, and the triols derived from them, are versatil

60 s by the combined use of cyclophellitol beta-epoxide- and beta-aziridine ABPs.

61 pective on the current state of the field of epoxide/anhydride copolymerization mediated by discrete

62 sters via the copolymerization of a range of epoxide/anhydride monomer pairs.

63 and ring-opening copolymerization (ROCOP) of epoxides, anhydrides, and CO2 is investigated, using bot

64 actones and ring-opening copolymerization of epoxides/anhydrides.

65 ncluding olefins, alkynes, heterocycles, and epoxides are competent traps in the bromonium-induced cy

66 The omega-3 endocannabinoid epoxides are derived from docosahexaenoic acid (DHA) and

67 In summary, the omega-3 endocannabinoid epoxides are found at concentrations comparable to those

68 Levels of DHA-derived epoxides are lower in colon tissues from patients with U

69 1,2-Disubstituted epoxides are opened under both conditions to form predom

70 Epoxides are versatile intermediates in organic synthesi

71 nctional groups, including esters, nitriles, epoxides, aryl boronic esters, terminal alkenes, silyl e

72 Together, these findings identify omega-3 epoxides as important regulators of inflammation and aut

73 a thermal rearrangement of cyclopentadienone epoxides as key step.

74 cs, we identify omega-3 (omega-3) fatty acid epoxides as new mast cell-derived lipid mediators and sh

75 tingly, cylcoalkenes yield the corresponding epoxides as products.

76 e-pot, sequential protocol was developed for epoxide azidolysis and copper-catalyzed azide-alkyne cyc

77 , structurally related surrogates containing epoxide bioisosteres were introduced and have become use

78 Benzo[a]pyrene,diol epoxide (BPDE) is a potent cigarette smoke carcinogen th

79 tabolite benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE), using methodology applicable to correlat

80 tabolically activated to benzo[a]pyrene diol epoxide (BPDE), which then can react with DNA to form ca

81 The epoxides, but not their urea, amide, or carbamate isoste

82 In addition, ring-opening of epoxide by an intermediate comprising multiple carboxyla

83 Using an approach based on the activation of epoxides by Lewis acids and of CO2 by appropriate cation

84 polymerization of carbonyl sulfide (COS) and epoxides by metal-free Lewis pair catalysts composed of

85 an example, it is applied to the opening of epoxides by titanocene in THF, a catalytic system with a

86 his isomerization is a dihydroxy hydroperoxy epoxide (C5H10O5), which is expected to have a saturatio

87 functional groups including ethers, esters, epoxides, carbamates, and phthalimides.

88 In addition other 5,6-epoxide carotenoids, such as (all-E)-neoxanthin, (9'Z)-n

89 ation of the GCase inhibitor conduritol beta-epoxide (CBE), as well as the nonlysosomal beta-glucosid

90 e GCase-irreversible inhibitor, conduritol B epoxide (CBE), reproduced the APP/alpha-synuclein aggreg

91 idase (GCase) in N2a cells with conduritol B epoxide (CBE).

92 Specifically, epoxide chemistry is used to covalently attach the 5'hmC

93 uction of amphiphilic polycarbonates through epoxides/CO2 coupling is a challenging aim to provide mo

94 copolymerization of EO or PO with functional epoxide comonomers are presented as well as complex bran

95 trans-stilbene (compound 1) and its stilbene epoxide (compound 2).

96 a 12-member macrolide ring with an extended epoxide-containing side chain.

97 iolaxanthin cycle (VAZ cycle) and the lutein epoxide cycle (LxL cycle) are two xanthophyll cycles fou

98 accumulates lutein via an engineered lutein epoxide cycle.

99 hydroxyl protected forms of the cyclohexane epoxides cyclophellitol and 1,6-epi-cyclophellitol.

100 ained microtubule stabilizing effects, and T-epoxide demonstrated antitumor effects in a xenograft mo

101 butane pyrimidine dimers (CPDs) and BaP diol epoxide-deoxyguanosine (BPDE-dG), which are removed from

102 Hence, its epoxide derivatives should serve as promising monomers f

103 imits tissue levels of cytochrome P450 (CYP) epoxides derived from omega-6 and omega-3 polyunsaturate

104 The epoxide exhibited reduced cytotoxicity toward its produc

105 position analysis of the nanoparticles after epoxide exposure reveals the presence of high molecular

106 h catalytic efficiency for the activation of epoxides, facilitating the quantitative chemical fixatio

107 via the oxidative addition of nickel(0) with epoxides featuring ketones.

108 report the design and the synthesis of a new epoxide fluorescent probe 7-glycidyloxy-9-(2-glycidyloxy

109 es on an asymmetric thiocarboxylysis of meso-epoxides, followed by an intramolecular trans-esterifica

110 lic activation of aflatoxin B1 (AFB1) to its epoxide form that reacts with N7 guanine in DNA.

111 olation of various thymine and thymidine 5,6-epoxides from the corresponding trans-5,6-bromohydrins b

112 SELEX, silane chemistry was used to prepare epoxide-functionalized glass microbeads (EGBs, 500 mum i

113 fatty amides, aldehydes, ketones, alcohols, epoxides, furans, pyrans and terpenic oxygenated derivat

114 5 times (CO2/epoxide) or 40 times (anhydride/epoxide) greater activity.

115 rly stage introduction of the trisubstituted epoxide group is reported, allowing access to the natura

116 undergoes covalent modification by the 12,13-epoxide group of triptolide.

117 Stability of the epoxide group was also studied under liquid chromatograp

118 a "click" reaction between the amine and an epoxide group.

119 d graphene oxide membranes, with ring-opened epoxide groups, verify this unique deformation mechanism

120 arton reaction, initially described for acyl epoxides, has been studied using the structurally simila

121 Here, we tested whether epoxides have an effect on Cif levels in OMVs.

122 highest versus lowest quartile of heptachlor epoxide, HCB, and mirex, although these exposures were c

123 and cis-nonachlors (TN, CN), heptachlor exo-epoxide (HEPX), dieldrin (DIEL), chlorobornanes (SigmaCH

124 mediates shed some light on the mechanism of epoxide hydrogenolysis, and further, deuterium labeling

125 We show that cholesterol epoxide hydrolase (ChEH) metabolizes 5,6-EC into cholest

126 uctural underpinnings of the enzyme's unique epoxide hydrolase (EH) activity, involving Zn(2+), Y383,

127 Juvenile hormone epoxide hydrolase (JHEH) has attracted great interest be

128 n of dual-target ligands that target soluble epoxide hydrolase (sEH) and the peroxisome proliferator-

129 Here we identify soluble epoxide hydrolase (sEH) as a key enzyme that initiates p

130 Using human soluble epoxide hydrolase (sEH) as a model antigen, we were able

131 l trials combined with inhibition of soluble epoxide hydrolase (sEH) as anti-inflammatory strategy pr

132 enetic ablation or inhibition of the soluble epoxide hydrolase (sEH) enzyme led to increased levels o

133 revious study showed that inhibiting soluble epoxide hydrolase (sEH) increased EET concentration and

134 Soluble epoxide hydrolase (sEH) is a bifunctional enzyme located

135 Soluble epoxide hydrolase (sEH) is an emerging therapeutic targe

136 Soluble epoxide hydrolase (sEH) is inhibited by electrophilic li

137 cids (EETs) from the cytochrome P450/soluble epoxide hydrolase (sEH) pathway are important eicosanoid

138 ne, and because its protein product, soluble epoxide hydrolase (sEH), converts bioactive epoxides of

139 peutic target for pain is the enzyme soluble epoxide hydrolase (sEH).

140 Soluble epoxide hydrolase (sEH; encoded by Ephx2) deficiency and

141 as a set of rare and common variants in the Epoxide Hydrolase 2 (EPHX2) gene, in an initial sequenci

142 Because epoxide hydrolase 2 (EPHX2) was identified as a novel AN

143 oli expressing recombinant Aspergillus niger epoxide hydrolase as the model enzyme for various enanti

144 nd immunological evidence that the bacterial epoxide hydrolase Cif disrupts resolution pathways durin

145 he hypotheses that inhibition of the soluble epoxide hydrolase enzyme can result in an increase in th

146 The soluble epoxide hydrolase enzyme catalyzes the hydrolysis of ant

147 CIMB 13064, and haloalcohol dehalogenase and epoxide hydrolase from Agrobacterium radiobacter AD1.

148 cificity that implicates participation of an epoxide hydrolase in converting epoxyalcohol to triol.

149 Treatment with soluble epoxide hydrolase inhibitor significantly reduces the ac

150 respectively) in the cytochrome P450/soluble epoxide hydrolase pathway.

151 e report findings that inhibition of soluble epoxide hydrolase reduces inflammation, oxidative stress

152 eficial biofilm was engineered to produce an epoxide hydrolase so that it efficiently removes the env

153 Like Cif, aCif is an epoxide hydrolase that carries an N-terminal secretion s

154 in Pseudomonas aeruginosa, Cif is a secreted epoxide hydrolase that is transcriptionally regulated by

155 peptidases, aldosterone synthase and soluble epoxide hydrolase, agonists of natriuretic peptide A and

156 Here, we show that a secreted P. aeruginosa epoxide hydrolase, cystic fibrosis transmembrane conduct

157 ic system that was catalysed by limonene-1,2-epoxide hydrolase, had an intracellular nature and was c

158 During lasalocid A biosynthesis, an epoxide hydrolase, Lsd19, converts the bisepoxy polyketi

159 utoantigens, and glutamate dehydrogenase and epoxide hydrolase-2 as additional autoantigens.

160 es, a reaction specificity characteristic of epoxide hydrolase.

161 identified inhibitors of the enzyme soluble epoxide hydrolase.

162 s the founding member of a distinct class of epoxide hydrolases (EHs) that triggers the catalysis-dep

163 squalene epoxidases, triterpenoid synthases, epoxide hydrolases, cytochrome P450s, and UDP-glucosyltr

164 for epoxide selection by ionophore polyether epoxide hydrolases.

165 osynthetic pathway resembles other polyether epoxide hydrolases/cyclases of the MonB family, but SalB

166 It catalyzes epoxide hydrolysis, but there is no known role for natur

167 ido)-dodecanoic acid (AUDA), an inhibitor of epoxide hydrolysis, inhibited VCAM-1 and ICAM-1 expressi

168 A catalytic system for titanocene-catalyzed epoxide hydrosilylation is described.

169 groundbreaking examples include the role of epoxides in aerosol formation especially from isoprene,

170 ysis, but there is no known role for natural epoxides in CFTR regulation.

171 zed Meinwald rearrangement reactions of five epoxides in dichloromethane solution have been studied a

172 drogen peroxide, providing the corresponding epoxides in good to excellent yields and enantioselectiv

173 ggest an unanticipated role of physiological epoxides in intracellular protein trafficking.

174 a,beta-unsaturated carbonyl derivatives with epoxides in the presence of a homogeneous acid catalyst

175 The indirect anodic oxidation of chalcone epoxides in the presence of electron-rich heteroarenes m

176 Using the hydrolysis of epoxides in water as a model reaction, the effect of mul

177 taining an exocyclic methylene instead of an epoxide, indicating that the FMO is involved in epoxidat

178 onal groups, including an alcohol, aldehyde, epoxide, indole, nitroalkane, and sulfide.

179 ce using the covalent inhibitor conduritol-B-epoxide induced a profound increase in soluble alpha-syn

180 two critical construction reactions: (1) an epoxide-initiated, beta-ketoester-terminated polycycliza

181 med to an alpha-hydroxy ketone moiety via an epoxide intermediate (3).

182 ompounds we found that the synthetic maresin epoxide intermediate 13S,14S-eMaR (13S,14S-epoxy- 4Z,7Z,

183 nal enzyme that converts the highly unstable epoxide intermediate LTA4 into LTB4, a potent leukocyte

184 on in which isocyanides are able to open the epoxide intermediate of the Bargellini reaction affordin

185 he hydrogenolysis between two diastereomeric epoxide intermediates shed some light on the mechanism o

186 tic resolutions of complex chlorinated vinyl epoxide intermediates, and Z-selective alkene cross meta

187 Conduritol B epoxide is an inhibitor of acid beta-glucosidase, and lo

188 The first step of the ring opening of the epoxide is the rate-determining step of these reactions.

189 electron transfer between Med*+ and chalcone epoxides is facilitated by an electron-rich heteroarene

190 ly oxidation of olefins to the corresponding epoxides is reported using polyfluoroalkyl ketones as ef

191 Metalations of arenes, epoxides, ketones, hydrazones, dienes, and alkyl and vin

192 ways, particularly for the abeo-abietane tri-epoxide lactone triptolide.

193 duced the steady-state production of omega-3 epoxides, leading to attenuated mast cell activation and

194 Opening of propargyl epoxides leads to 1,2-diborylated butadienes probably vi

195 in situ via base-induced ring opening of the epoxide-leads to the syn-selective production of alpha-a

196 d Asp are implicated as proton donors to the epoxide leaving group.

197 are proposed to act via a 1,2-anhydrosugar "epoxide" mechanism that proceeds through an unusual conf

198 of oxygen- and nitrogen-tethered alkynes and epoxide mediated by Lewis acid under ambient conditions

199 uct formed between deoxyguanosine and a diol epoxide metabolite of BaP, with subsequent mutation of c

200 Four TPs (carbamazepine-10,11-epoxide, metoprolol acid, 1-naphthol, and saluamine) wer

201 Conduritol B epoxide mitigated gene dysregulation in the spinal cord

202 wed by tungsten-induced deoxygenation of the epoxide moiety.

203 We describe a novel epoxide monomer with methyl-thioether moiety, 2-(methylt

204 ith a particular focus on the most important epoxide monomers ethylene oxide (EO), propylene oxide (P

205 ed access to the oppositely configured 12,13-epoxides of 12-epoxyobtusallene II and 12-epoxyobtusalle

206 epoxide hydrolase (sEH), converts bioactive epoxides of polyunsaturated fatty acid (PUFA) to the cor

207 We evaluated synthetic omega-3 epoxides of saturated fatty acids as antiproliferative a

208 is one involving an intermediate bearing an epoxide on carbons 1 and 2.

209 rategies involving BF3.Et2O-catalyzed ketone-epoxide opening and gold-catalyzed glycosylation reactio

210 The same sequence employing an epoxidation/epoxide opening in place of dihydroxylation furnishes ma

211 glucose were synthesized by stereocontrolled epoxide opening of hydroxyl protected forms of the cyclo

212 l products involves a kinetically disfavored epoxide-opening cyclic ether formation, a reaction terme

213 ilities involving the formation of either an epoxide or an oxetane.

214 modinuclear complexes, it shows 5 times (CO2/epoxide) or 40 times (anhydride/epoxide) greater activit

215 ycosylation with Schmidt-type donors, glycal epoxides, or under dehydrative conditions with C1 alcoho

216 lize the first dyotropic rearrangement of an epoxide-oxetane substrate.

217 lymerization, and cationic polymerization of epoxides (oxiranes), are briefly reviewed.

218 Taken together, the omega-3 endocannabinoid epoxides' physiological effects are mediated through bot

219 Our results suggest that epoxides play an important role in the growth of atmosph

220 n the iron(II) oxidation state and selective epoxide polymerization was observed in the iron(III) oxi

221 With the ever growing toolbox for epoxide polymerization, a "polyether universe" may be en

222 ent and in some cases metal-free methods for epoxide polymerization, i.e., the activated monomer stra

223 ep in Q biosynthesis is the reduction of the epoxide precursor, epoxyqueuosine, to yield the Q cyclop

224 amyotrophic lateral sclerosis, conduritol B epoxide preserved ganglioside distribution at the neurom

225 ge-fleshed fruit, whereas several carotenoid epoxides prevailed in yellow-fleshed fruit.

226 Mechanistically, the omega-3 epoxides promote IgE-mediated activation of mast cells b

227 The diol:epoxide ratios suggest the sEH activity is higher in AN

228 niques, we were successful in identifying an epoxide reactive metabolite, which upon conjugation with

229 d other 4-hydroxycoumarins inhibit vitamin K epoxide reductase (VKOR) by depleting reduced vitamin K

230 d revealed the essential role of a vitamin K epoxide reductase (VKOR) gene in pilus assembly.

231 Vitamin K epoxide reductase (VKOR) is an essential enzyme for vita

232 ing the mammalian membrane protein vitamin K epoxide reductase (VKORc1) as a reporter, we describe a

233 rp mutation results in reduced vitamin K 2,3-epoxide reductase activity, the molecular mechanism unde

234 ncharacterized ER membrane protein vitamin K epoxide reductase complex subunit 1 variant 2 (VKORC1v2)

235 th a novel membrane protein termed vitamin K epoxide reductase complex subunit 1 variant 2 (VKORC1v2)

236 ncharacterized ER-resident protein vitamin K epoxide reductase complex subunit 1 variant 2 (VKORC1v2)

237 vIL-6 with the ER membrane protein vitamin K epoxide reductase complex subunit 1 variant 2 (VKORC1v2)

238 ular interactions by inhibition of vitamin K epoxide reductase, cellular responses including altered

239 To understand how QueG is able to perform epoxide reduction, an unprecedented reaction for a Cbl-d

240 This epoxide results from the diastereoselective epoxidation,

241 tic activities of LTA4H, alternating between epoxide ring opening and peptide bond hydrolysis, assist

242 inetics and isotope labeling studies suggest epoxide ring opening as the turnover limiting step in ou

243 FEPO functions via epoxide ring opening upon nucleophilic attack of H2S.

244 A sequence of epoxide ring opening using N-deprotonated 1,2-azaborines

245 ivatives as well as compounds resulting from epoxide ring opening, exemplified by epoxydiol.

246 MWCNT with GMA produces MWCNT-g-GMA and the epoxide ring present in the GMA upon reaction with allyl

247 on catalyst on the regioselectivities of the epoxide ring-opening and acylation steps.

248 ard sequential reactions with a nucleophile (epoxide ring-opening by chloride) and an electrophile (O

249 onal group transformations that deviate from epoxide ring-opening reactions, discovered through nanom

250 stereocontrolled DMDO oxidation; subsequent epoxide ring-openings with various nucleophiles can proc

251 poxidation and elaborated via regioselective epoxide-ring opening and diastereoselective bromoetherif

252 onyl-phenol adducts were produced firstly by epoxide-ring opening initiated by the attack of one phen

253 The preparative scale electrolysis generated epoxide-ring-opened/Friedel-Crafts arylation products in

254 We propose a general mechanism for epoxide selection by ionophore polyether epoxide hydrola

255 t is transcriptionally regulated by CifR, an epoxide-sensitive repressor.

256 tural analysis and comparison with unreacted epoxides show that this compound indeed binds in the (4)

257 Thus, the PAF-AH2-omega-3 epoxide-Srcin1 axis presents new potential drug targets

258 ation of alpha,beta-unsaturated carbonyl and epoxide substituents.

259 no lesion formed in the reaction of DNA with epoxides substituted with good leaving groups (e.g. viny

260 Using a moderate reducing agent and an epoxide substrate analogue, we were now able to trap and

261 Epoxide substrates of sEH and associated oxylipins were

262 esults in high serum levels of vitamin K 2,3-epoxide, suggesting that supplemented vitamin K is reduc

263 nd T3R, as the reaction product of T3O is an epoxide that is not used as a substrate by T3R.

264 ioselective nucleophilic opening of a unique epoxide that provides access to a small library of compo

265 ated by the production of toxic DGLA-derived epoxides that trigger germ cell destruction.

266 ugh derived specifically from the opening of epoxides, the prediction capabilities of the model, buil

267 (24) comprise two steps: ring opening of the epoxide to a carbocation intermediate followed by migrat

268 arbonylation of an enantiomerically pure cis-epoxide to a trans-beta-lactone.

269 show that in vivo VKORC1L1 reduces vitamin K epoxide to support vitamin K-dependent carboxylation as

270 trophile coupling of aryl bromides with meso-epoxides to form trans-beta-arylcycloalkanols is present

271 ed to the kinetic resolution of select trans-epoxides to give synthetically useful selectivity factor

272 within cytosol and peroxisomes that converts epoxides to the corresponding diols and hydrolyzes phosp

273 ective Bronsted acid catalyzed conversion of epoxides to thiiranes has been developed.

274 omenon in graphene oxide membranes, covalent epoxide-to-ether functional group transformations that d

275 anthin (all-E)-antheraxanthin and lutein 5,6-epoxide, together with (all-E)-lutein, (all-E)-zeaxanthi

276 ization reaction of boron-containing alkynyl epoxides toward C2- and C3-borylated furans has been dev

277 that OMV shape and density were affected by epoxide treatment, with two distinct vesicle fractions p

278 ar catalyst for the cycloaddition of CO2 and epoxides under ambient conditions.

279 des, a vinyl halide, and a vinyl triflate to epoxides under reducing conditions.

280 Relay Chemistry (ARC) tactic, and a dithiane-epoxide union in conjunction with an oxazole-directed st

281 uorophore, and is equipped with an operating epoxide unit.

282 all cases, S(N)2-type ring opening of these epoxides upon treatment with aqueous H2SO4 proceeded by

283 tive intermediates in catalytic reactions of epoxides using nickel, but have never been isolated or e

284 acid nanoparticles of 4-20 nm are exposed to epoxide vapors, dependent on the particle size and relat

285 rization of a broad array of monomers (e.g., epoxides, vinyl ethers, alkenes, cyclic ethers, and lact

286 yls, isoprene epoxydiol and methacrylic acid epoxide was incorporated in the Community Multiscale Air

287 -epoxy-4-oxo-beta-apo-11-carotenal, no other epoxides were detected.

288 Different types of aldehydes and epoxides were identified and quantified, above all in th

289 was active for the polymerization of various epoxides, whereas the analogous neutral iron(II) complex

290 c species, of the same molecular mass as the epoxide, which transforms to an intermediate that matche

291 sesquiterpene metabolism to a sesquiterpene epoxide, which we designate arteannuin X.

292 we developed a kinetic resolution of racemic epoxides, which proceeds with high selectivity (up to s

293 te N-acetylneuraminic acid (Neu5Ac) 2,3-beta-epoxide with an alcohol provided the 3-hydroxy alpha-gly

294 f facile intramolecular reaction between the epoxide with the carboxylic acid in 2.

295 d from S(N)2-like reactions of the silylated epoxide with the diene, in which stereospecific ring ope

296 time through the anionic copolymerization of epoxides with CO2, under metal-free conditions.

297 ring-opening alternating copolymerization of epoxides with cyclic anhydrides.

298 e developed method was applicable to various epoxides with diverse N- and O-nucleophiles affording th

299 o the discovery of two new reaction modes of epoxides with sulfones.

300 Nucleophilic ring-opening of the epoxides with water, alcohols, and HF proceeded with hig