ライフサイエンスコーパス: equilibrium constant

1 produce a relatively weak dependence in the equilibrium constant.

2 cal temperature is defined by the 'reaction' equilibrium constant.

3 nalysis of the temperature dependence of the equilibrium constant.

4 imately 3.2) but had almost no effect on the equilibrium constant.

5 uilibria from the pressure dependence of the equilibrium constant.

6 T and yielded a pH-dependent oligomerization equilibrium constant.

7 d binds in the groove with an unusually high equilibrium constant.

8 spholipid bilayer and determined its binding equilibrium constant.

9 tent with the low dimer-monomer dissociation equilibrium constant.

10 ) having mutations that increased the gating equilibrium constant.

11 ncluded xenon atom substantially changes the equilibrium constant.

12 provides an experimental measurement of the equilibrium constant.

13 at the necessary ratio to create the desired equilibrium constant.

14 he two states influences the C<-->O "gating" equilibrium constant.

15 ss for which we have determined the rate and equilibrium constants.

16 of mouse neuromuscular AChR gating rate and equilibrium constants.

17 a consequence of altering the thermodynamic equilibrium constants.

18 MR technique in precisely measuring relative equilibrium constants.

19 iation of ApoE and are in agreement with the equilibrium constants.

20 from the water virial equation of state and equilibrium constants.

21 n of separation conditions and estimation of equilibrium constants.

22 free energy and impacting reaction rate and equilibrium constants.

23 orage, and sulphur dioxide-aldehyde apparent equilibrium constants.

24 isotope, seven rate constants in all and two equilibrium constants.

25 The monomer-dimer equilibrium constant (~20 mum) and the CXCR2 binding con

26 ombination of the unbinding kinetics and the equilibrium constant allows the binding rate of a peptid

27 the strong adsorption sites and 24% for the equilibrium constant and 5% for the saturation capacity

28 s of the isotherm parameters were 5% for the equilibrium constant and 9% for the saturation capacity

29 cterized by a very high value of the partial equilibrium constant and large positive changes in the a

30 Equilibrium constant and photostationary state measureme

31 rg(3') in the alpha-subunit alter the gating equilibrium constant and reduce channel expression.

32 reas supramolecular crosslinks depend on the equilibrium constant and relative concentrations of cros

33 y 10 A from the Cd(2+) site affects both the equilibrium constant and the residence time of water, wh

34 action amplitudes confirm a strain-invariant equilibrium constant and thus a strain-insensitive ratio

35 le to recover both experimentally determined equilibrium constants and association/dissociation rates

36 nge (REX) protocol are applied to obtain the equilibrium constants and atomic details of the ionizati

37 the same reaction in free solution, and the equilibrium constants and dissociation and association r

38 anol dehydration are used to obtain rate and equilibrium constants and energies for intermediates and

39 ndom errors on the accuracy and precision of equilibrium constants and enthalpy changes determined by

40 lorimeters for simultaneous determination of equilibrium constants and enthalpy changes, for determin

41 s of complex I and complex II, pH effects on equilibrium constants and enzyme kinetics, and the acid-

42 ectrum, allowing the direct determination of equilibrium constants and free energy differences.

43 incomplete definitions of ligand binding and equilibrium constants and neglect of the non-ideality of

44 opped flow kinetics were used to measure the equilibrium constants and rates of nucleotide binding an

45 vis spectrophotometry afforded derivation of equilibrium constants and reaction enthalpies.

46 tration dependence and allows extracting the equilibrium constants and spectra of the distinct specie

47 Comparison of the equilibrium constants and thermodynamic parameters Delta

48 The determination of equilibrium constants and thermodynamic properties of th

49 ations to alanine reduce the liganded-gating equilibrium constant, and solved the crystal structures

50 et, restored normal O2 dissociation rate and equilibrium constants, and reduced O2-alphaHb autooxidat

51 The measured equilibrium constants, and the determined pK(a) and E(1/

52 The monomer/dimer equilibrium constants are between K(dim) = 10(5) M(-1) a

53 These equilibrium constants are consistent with the solution b

54 Gating rate and equilibrium constants are estimated for seven different

55 he molecular basis of such phenomena is that equilibrium constants are generally measured in three-di

56 The equilibrium constants are largest for tertiary alkyl hal

57 The equilibrium constants are largest for the nitrile deriva

58 and unfolding rate constants and the overall equilibrium constant as probes of surface area changes i

59 his regime include the potential for gaining equilibrium constants as well as rate constants, and for

60 ha-epsilon; therefore, the diliganded gating equilibrium constant at -100 mV is comparable for both r

61 The Phax left arrow over right arrow Pheq equilibrium constants at 103 K are 2.21 for 1 and 4.59 f

62 mine to the carbamic acid formation rate and equilibrium constants at 25.0 degrees C has been establi

63 ked over either of the dipyridyl groups; the equilibrium constant between the bistable states was fou

64 zonal elution studies to measure association equilibrium constants between immobilized AGP and R- or

65 the rotational diffusion does not change the equilibrium constants, but significantly affects the dyn

66 nd 80% (stem) and increased the dissociation equilibrium constant by 1.8-fold as determined by surfac

67 no acids with alanine lowered the adsorption equilibrium constant by 5-fold and the maximal surface c

68 This ratio is then used with equilibrium constants calculated for the specific pressu

69 We show that the ratio between the 2D and 3D equilibrium constants can be expressed as a product of i

70 The measured equilibrium constants can be expressed by the sum of two

71 icted fold-increase in the diliganded gating equilibrium constant caused by each mutation alone.

72 ass drug (S-warfarin) and had activities and equilibrium constants comparable to those for soluble HS

73 use of simulations can lead to estimates of equilibrium constant corrections due to complex dissocia

74 predictions based on independently measured equilibrium constants corroborate experimental data of s

75 , limited information regarding the rate and equilibrium constants defining the ATPase cycle of RNA h

76 Deterpmination of equilibrium constants describing chemical reactions in t

77 s shown that a temperature jump perturbs the equilibrium constant directly to increase tension.

78 We estimated the monoliganded gating equilibrium constant E(1) and the energy change associat

79 stant only by changing the unliganded gating equilibrium constant (E(0)) and did not alter the energy

80 different constructs, the unliganded gating equilibrium constant (E(0)) was correlated with the prod

81 we measured changes in the diliganded gating equilibrium constant (E(2)) consequent to mutations of r

82 s were quantified: 1), the diliganded gating equilibrium constant (E(2)), which reflects the energy d

83 Knowing both the di- and unliganded gating equilibrium constants (E(2) and E(0)) is a foundation fo

84 uilibrium, cyclic energy delivery than under equilibrium constant energy conditions were identified.

85 d for determining accurate electron-transfer equilibrium constants even when dimer radical cations ar

86 Although the internal equilibrium constant favored oxidation, the overall K(eq

87 Mutarotation equilibrium constants favored the alpha anomer over the

88 switching thermodynamics; while a switching equilibrium constant favoring the nonbinding, nonsignali

89 Gibbs free energy, the keto-enol tautomeric equilibrium constant for 2,3-dihydroxycycloprop-2-en-1-o

90 The equilibrium constant for 2a + ArOH <==> 1a + ArO(*) is (

91 nstant for Abeta degradation by CatB and the equilibrium constant for binding of CysC to Abeta were d

92 trated with pH consistent with the change in equilibrium constant for denaturation.

93 the dimer dissociation rate constant and the equilibrium constant for dimerization.

94 In contrast, both the rate constant and equilibrium constant for DNA opening (I(1) to I(2)) are

95 highly favorable, and we calculate that the equilibrium constant for flipping is approximately 1300.

96 e mutant protein retained a highly favorable equilibrium constant for flipping the 1,N(6)-ethenoadeni

97 ncrease in the stability, as measured by the equilibrium constant for folding, for the globular prote

98 he bilayer/solution interface that alter the equilibrium constant for gA channel formation, and thus

99 d 2.3 x 10(-2) s(-1), respectively, with the equilibrium constant for hybridization as 4.2 x 10(6) M(

100 ge effects of [urea] and [salt] on K(3) (the equilibrium constant for I(2) is in equilibrium with RP(

101 The equilibrium constant for intramolecular docking is obtai

102 nsitive PFL-AE to determine the kinetics and equilibrium constant for its interaction with PFL.

103 easurements showing that the drug shifts the equilibrium constant for myosin-catalyzed ATP hydrolysis

104 airpin motifs do produce enhancements in the equilibrium constant for nucleation in aggregation react

105 greater than 5 x 10(9)-fold increase in the equilibrium constant for proton transfer from C-6, so th

106 -3 positions decreased the forward rate and equilibrium constant for reversible strand ligation by 1

107 n corresponding to 1/K(S), where K(S) is the equilibrium constant for solvation of a carboxylic acid

108 Furthermore, the equilibrium constant for the conformational change (K(2)

109 The equilibrium constant for the cross-bridge force generati

110 from adsorbed alkanols or ethers and on the equilibrium constant for the formation of unreactive rea

111 However, the equilibrium constant for the intramolecular step (K(4))

112 The equilibrium constant for the reaction was measured at pH

113 ermined to be 41.0 kcal/mol by measuring the equilibrium constant for this reaction using three diffe

114 hat allows extraction of the enantiospecific equilibrium constants for (R)- and (S)-propylene oxide a

115 ng side chain statistical data, we calculate equilibrium constants for a great number of amino acid r

116 g assay was used to accurately determine the equilibrium constants for AdoMet binding to PFL-AE alone

117 model is applied to calculate free energies/equilibrium constants for adsorption on the individual s

118 onse curve (CRC) is determined by underlying equilibrium constants for agonist binding and receptor c

119 Equilibrium constants for alkoxides formed by protonatio

120 The apparent equilibrium constants for base pair opening were measure

121 The rates (kon and koff) and equilibrium constants for both reactions were determined

122 e native and denatured states as well as the equilibrium constants for denaturation of the different

123 formation was observed in several cases and equilibrium constants for dimerization were determined.

124 ine both the dissociation rate constants and equilibrium constants for drug-protein interactions in s

125 y two different methods: first, by measuring equilibrium constants for electron exchange between the

126 The association equilibrium constants for hemin binding to wild-type, M6

127 Analysis of the kinetic data yields equilibrium constants for intramolecular loop formation

128 Comparison of the rate and equilibrium constants for LIG3 and LIG1 nevertheless rev

129 The relative equilibrium constants for ligand substitution span over

130 , U-1*G22, C-2*G23 and A2*U21 showed unusual equilibrium constants for opening and possible implicati

131 e to learn how to predict reaction rates and equilibrium constants for reactions involving adsorbed m

132 le process, we estimated the gating rate and equilibrium constants for receptors with point mutations

133 single-channel electrophysiology, the gating equilibrium constants for receptors with zero, one or tw

134 Phe-tRNA(Phe), 18-55 and 19-56, on rate and equilibrium constants for specific steps of this cycle,

135 Theoretical calculation of both the rate and equilibrium constants for such reactions requires knowin

136 Theoretical estimates of rate and equilibrium constants for surface reactions and CO adsor

137 free energy relationships based on rate and equilibrium constants for the binding of these peptides

138 The equilibrium constants for the conversion of PhXn(+) to P

139 best fit model took into account two acidity equilibrium constants for the Fe(II) complexing ligands

140 As equilibrium constants for the formation of Br(2)O and Br

141 and, based on the mechanism, the kinetic and equilibrium constants for the formation of carbamic acid

142 The rate of the reversible reactions and the equilibrium constants for the formation of carbamic acid

143 tion relating the kinetic rate constants and equilibrium constants for the formation of carbamic acid

144 DNA cleavage reaction by measuring rate and equilibrium constants for the individual reaction steps

145 Rate and equilibrium constants for the reaction between N-aryl tr

146 ation of both the kinetic rate constants and equilibrium constants for the reaction of CO(2)(aq) with

147 uctures of the key proteins and the rate and equilibrium constants for the reactions for comparison w

148 At T=298.15K the equilibrium constants for the tartrazine-BSA and HSA com

149 folding transitions and determined rate and equilibrium constants for the transitions between these

150 cities of the amino acids as measured by the equilibrium constants for transfer of their side-chains

151 rption constants for orthoclase with aqueous equilibrium constants for uranyl carbonate species indic

152 ves four recombination rate constants and an equilibrium constant, for each trace isotope, seven rate

153 les, G(z,f), as a function of z, obtained in equilibrium constant force simulations, reveal the inter

154 Equilibrium constants, forward and reverse rate constant

155 f macromolecular complexes with dissociation equilibrium constants from picomolar to micromolar.

156 The equilibrium constant governing interconversion of the su

157 e on DNA by BirA is exquisitely tuned by the equilibrium constant governing its homodimerization.

158 tic data afforded estimates for the rate and equilibrium constants governing the formation of (SSB)60

159 pyryliums (Pylm) form dimers quantitatively (equilibrium constants >10(4) M(-1)), but they enter as s

160 The radical-dimer equilibrium constant has been determined to be 5.7 x 10

161 Equilibrium constants have been determined from the sedi

162 transfer rate constants, and the adsorption equilibrium constant in the low-pressure range.

163 Equilibrium constants in Cu-based atom transfer radical

164 luding concentrations, kinetic constants and equilibrium constants in modeling and simulating complex

165 Arrestin2 self-association equilibrium constants in the presence of 100 microM IP6

166 e estimates of the corresponding ion binding equilibrium constants indicate that the iodide concentra

167 The correlation of rate and equilibrium constants indicates that this effect has a t

168 lso introducing optional isomerizations with equilibrium constants inversely related to the number of

169 nformation; (iv) the ACh-monoliganded gating equilibrium constant is approximately 1.7 x 10(-3); (v)

170 The logarithm of the equilibrium constant is plotted versus inverse temperatu

171 The unliganded gating equilibrium constant is smaller and less voltage-depende

172 Despite these changes in rate, the equilibrium constant is strain-insensitive.

173 ge of their hydrolysis and corresponding low equilibrium constants, it is unlikely that these species

174 approximately +28 kcal/mol at 200 degrees C, equilibrium constant K approximately 10(-13)).

175 break up, we also use these to calculate the equilibrium constant K associated with the monomer-dimer

176 We measured the equilibrium constant (K = 1264 M(-1) at 294 K) and, from

177 ees C: saturable binding with an association equilibrium constant (K(a)) of 1.1-1.9x10(5)M(-1) and no

178 nstants (k(a) and k(d)) and the dissociation equilibrium constant (K(D)) of smGN for calmodulin were

179 ree monomers, as defined by the dissociation equilibrium constant (K(D)), is required for the buildup

180 step (M.T M.D.P) is slow (12 s(-1)) and the equilibrium constant (K(H)) of 1 suggests significant re

181 rystals and octylamine ligands, the chemical equilibrium constant (K) of the CdSe-amine nanocrystal-l

182 Characteristic equilibrium constant (K), change of entropy (DeltaS), an

183 yed saturation kinetics with similar binding equilibrium constants (K(bind)) for each.

184 s are also carried out to obtain the binding equilibrium constants (K) of ligand-quadruplex interacti

185 The association equilibrium constants (K) were determined from NMR compe

186 ly detectable consistent with the determined equilibrium constant, K(1), of (1.9 +/- 0.4) x 10(-11) M

187 )H NMR spectra, were used in determining the equilibrium constant, K(298 K) = [Rh-OCH(3)(CH(3)OH)][Rh

188 h for simultaneous determination of both the equilibrium constant, K(d), and the unknown concentratio

189 We measured the equilibrium constant, K(eq), for the formation of X@1.

190 spheric observations have suggested that the equilibrium constant, K(eq), governing the balance betwe

191 e relative humidity, were used to obtain the equilibrium constant, K(P), for the water-mediated hydra

192 The four equilibrium constants, K(1) = (5 +/- 5) x 10(7) M(-1), K

193 Keto-enol equilibrium constants, K(T), at 25 degrees C were obtain

194 ine, forming and reaching pseudoequilibrium (equilibrium constant K1 = 1.87 x 10(3) M(-1)) with the c

195 eptor aggregation model when the aggregation equilibrium constant (Ka) was positive and greater than

196 data were used to determine the association equilibrium constants (Ka) or global affinities (nKa') a

197 nges in kint or by changes in the adsorption equilibrium constant (Kads-H+).

198 The adsorption equilibrium constants (Kads) were found to follow the se

199 thermodynamic model yielded the competition equilibrium constant (Kc), which in conjunction with ind

200 lack of sensitivity due to high dissociation equilibrium constant KD and non-specificity due to an ab

201 Equilibrium constant (KD) and maximum binding capacity o

202 Equilibrium constant (KD), maximum binding capacity (Rma

203 ceptor concentration (Bmax) and dissociation equilibrium constant (Kd).

204 Differences in the equilibrium constants Kdimer for early and late metals e

205 gy and thus >60-fold increase in the folding equilibrium constant (Keq) for excluded volume fractions

206 Thus, the equilibrium constant (Keq) increases by approximately 16

207 59W-Leuko-PNP has an on-enzyme thermodynamic equilibrium constant (Keq) near unity in the temperature

208 Differences in the equilibrium constants (Keq ) for early and late metals e

209 However, the estimated equilibrium constants (Keq) for U-V bearing minerals wer

210 by Freundlich isotherm model with adsorption equilibrium constant (KF) of 1.46 mL g(-1).

211 Plots of log k(2) versus the corresponding equilibrium constants (log K) or Bronsted basicities (pK

212 ciples that determine the values of rate and equilibrium constants measured by this system, using the

213 To this end, we used biochemical rate and equilibrium constant measurements as well as cryo-electr

214 mplete ET at ambient temperature but with an equilibrium constant near unity at 5 degrees C.

215 The values for the oxygen binding equilibrium constant obtained from the Michaelis-Menten

216 The ATRP equilibrium constants obtained vary over 7 orders of mag

217 The calculated equilibrium constant of 1.1 indicates that the beta-isom

218 The reaction has an equilibrium constant of 10 +/- 5 at 22 degrees C in favo

219 Thus, our results demonstrate that the equilibrium constant of a pre-existing conformational eq

220 The equilibrium constant of a reaction with thermodynamics c

221 is in fast exchange (<milliseconds) with an equilibrium constant of about 1 mM.

222 The "gating" equilibrium constant of acetylcholine receptor-channels

223 ure on the mobile phase viscosity and on the equilibrium constant of analytes, the band velocity is n

224 79N and DeltaK210 were associated with a K2 (equilibrium constant of cross-bridge detachment step) si

225 K0 (ADP association constant) and larger K4 (equilibrium constant of force generation step) relative

226 The equilibrium constant of metarhodopsin I-metarhodopsin II

227 ctrometry is used extensively to measure the equilibrium constant of noncovalent complexes.

228 n forces recapitulate a higher stability and equilibrium constant of the fibril-forming peptide, simi

229 The net folding rate is a product of the equilibrium constant of the highest-energy species and a

230 The equilibrium constant of the nicking reaction, which invo

231 n of the channel, but also by perturbing the equilibrium constant of the proton-sensing residue His37

232 The equilibrium constant of the reaction Ge(TArFP) + 2 py =

233 The equilibrium constant of the reaction Ge(TPP) + 2 py = Ge

234 on the rate of R-->R" transition, while the equilibrium constant of the T<-->R has a small effect on

235 complex activator, hWASp, with dissociation equilibrium constants of about 100 nM.

236 l currents and estimated the gating rate and equilibrium constants of adult mouse AChRs with mutation

237 s of the guests in the cavitands enhance the equilibrium constants of carbonyl additions, K/K(ctrl),

238 rea of calcite, adsorption surface areas and equilibrium constants of clay minerals, and cation excha

239 Rate and equilibrium constants of formation of the 1:1 and 1:2 co

240 experimentally known proton affinities, and equilibrium constants of intermediate reactions.

241 s been used almost exclusively for obtaining equilibrium constants of intermolecular interactions.

242 , we assign an error of 1.1-1.2 log unit for equilibrium constants of several reactions leading to ha

243 these measurements we calculated all of the equilibrium constants of the "allosteric" cycle as follo

244 The equilibrium constants of the binding follow a log-normal

245 ation does not affect either the rate or the equilibrium constants of the channel opening but does sl

246 min D allowed the calculation of the thermal equilibrium constants of the isomerization process.

247 wed for the estimation of exchange rates and equilibrium constants of the olefins.

248 ogress of chemical processes to the rate and equilibrium constants of the process.

249 usive mechanistic information but yields the equilibrium constants of the self-assembly process as co

250 The equilibrium constants of these processes show a linear r

251 The equilibrium constants of trans and cis dimerization of m

252 istent with the near independence of folding equilibrium constant on size.

253 ata, the dependence of the rate constant and equilibrium constant on the stall angle, as well as the

254 We examined the dependence of rate and equilibrium constants on concentration of denaturant and

255 channel block) changed the diliganded gating equilibrium constant only by changing the unliganded gat

256 A thermodynamic procedure avoiding equilibrium constants or other reaction models and not r

257 issociation kinetics and find a dimerization equilibrium constant orders of magnitude lower than prev

258 ystematically characterized the rate and the equilibrium constants pertinent to channel opening and c

259 esults in an increase in the channel-opening equilibrium constant ((Phi(-1) = k(op)/k(cl)) by a facto

260 n created taking into account the calculated equilibrium constants (pK(T)) for all tautomeric reactio

261 culating transition-state rate constants and equilibrium constants plus a phenomenological relaxation

262 Certain combinations of equilibrium constants produce the sharp critical concent

263 The ion-pair equilibrium constants ranged 10(4)-10(6) M(-1) in CH3CN

264 The reaction is reversible with equilibrium constants ranging from 1.2 to 2.

265 change is revealed by the slope of its rate-equilibrium constant relationship.

266 lyses based on changes in the channel gating equilibrium constant reveal strong energetic coupling am

267 sity functional theory estimates of rate and equilibrium constants show that the kinetically relevant

268 ChRs were designed to have specific rate and equilibrium constants simply by adding multiple, energet

269 rimetric methods have been used to determine equilibrium constants since 1937, but no comprehensive r

270 In the present work we report the equilibrium constant, stoichiometric ratio and the therm

271 ble reaction 2H(+) + 2e(-) <--> H(2) with an equilibrium constant that is dependent on the reducing p

272 Other equilibrium constants that are not readily measurable we

273 Here we measured rate and equilibrium constants that define the interaction of Ypt

274 The equilibrium constants that were determined also showed g

275 On the basis of the water dimer equilibrium constant, the effective rate coefficient of

276 eltaH(o) and DeltaS(o), including the gating equilibrium constant, the strength- and temperature depe

277 s of the binding free energy (affinity), the equilibrium constants, the kinetics and the specificity

278 g is capable of determining membrane-binding equilibrium constants through the reliable counting of i

279 ll require connection of individual rate and equilibrium constants to structural changes that occur i

280 We therefore measured the rate and equilibrium constants underlying Mss116 ATP utilization

281 The measured rate and equilibrium constants vary substantially with added wate

282 From these values and the diliganded gating equilibrium constants, we estimate that the unliganded A

283 The activation energy, turnover number, and equilibrium constant were 16.5 kcal/mol, 406 s(-1), and

284 These equilibrium constants were also measured for several mod

285 Five equilibrium constants were deduced using sinusoidal anal

286 Equilibrium constants were determined by fluorimetry fro

287 rmined using the triptycene scaffold and the equilibrium constants were determined by low-temperature

288 Rate and equilibrium constants were determined for protonation of

289 Equilibrium constants were determined.

290 Equilibrium constants were evaluated for reactions of (t

291 ic model, the oligomer dissociation rate and equilibrium constants were seen to depend not only on mo

292 tally determined value for the monomer-dimer equilibrium constant, which, for wild-type EGF receptors

293 N,N-acetals) were compared with experimental equilibrium constants, which are reported here for the f

294 or O(2) reactions with CO* and CO adsorption equilibrium constants, which reflect the respective acti

295 d reason, insufficient reactivity (e.g., low equilibrium constant), why o-phthalaldehyde and possibly

296 ly the free fraction of testosterone and its equilibrium constants with both these proteins in physio

297 ing the label-free determination of rate and equilibrium constants with respect to a specific binding

298 Excellent correlations of the equilibrium constants with the Cu(II/I) redox potentials

299 a substituent parameter and the dimerization equilibrium constant, with para electron-donating substi

300 gonist-independent constants--the activation equilibrium constant without agonists (E(0)) and the aff