ライフサイエンスコーパス: equilibrium dissociation constant

1 fibronectin (Fn) with a low nanomolar K(d) (equilibrium dissociation constant).

2 of immobilization on the Tir-IBD/Intimin-ECD equilibrium dissociation constant.

3 form stable homodimers with a submicromolar equilibrium dissociation constant.

4 raction and yield an accurate measure of the equilibrium dissociation constant.

5 a dimer, with little apparent change in the equilibrium dissociation constant.

6 e mutant, consistent with a smaller observed equilibrium dissociation constant.

7 n exponential relationship between these two equilibrium dissociation constants.

8 to eight of these nine residues and derived equilibrium dissociation constants.

9 force-dependent DNA intercalation rates and equilibrium dissociation constants.

10 complexes possessing nanomolar to picomolar equilibrium dissociation constants.

11 nded DNA but not single-stranded DNA or RNA (equilibrium dissociation constant = 16 nM).

12 exists primarily as an octamer in solution (equilibrium dissociation constant 6.5x10(-5) M) and leuc

13 with an approximately 8-fold increase of the equilibrium dissociation constant and an increase in DNA

14 ing analysis were performed to calculate the equilibrium dissociation constant and further characteri

15 The method was then used to measure the equilibrium dissociation constant and offrate of a 9-mer

16 s of dansyl- and fluoresceinyl-ACPs revealed equilibrium dissociation constants and dissociation rate

17 (FRET) acceptors in determination of protein equilibrium dissociation constants and kinetic rates.

18 Significant differences between the measured equilibrium dissociation constants and kinetically deriv

19 the similarities between the SPR-determined equilibrium dissociation constants and reported dissocia

20 e binds ssDNA oligonucleotides with nM-range equilibrium dissociation constants and some sequence spe

21 k(et) values as well as significantly higher equilibrium dissociation constants and steady-state K(m)

22 Data were analyzed to determine agonist KA (equilibrium dissociation constant) and EC50 values.

23 ptase inhibitors known to date with a 290 pm equilibrium dissociation constant, and provide the first

24 d determination of stoichiometry of binding, equilibrium dissociation constant, and thermodynamic par

25 Equilibrium dissociation constants are approximately 2.5

26 Equilibrium dissociation constants are derived independe

27 The equilibrium dissociation constants are quite small (1-85

28 possible to simultaneously abstract multiple equilibrium dissociation constants as a function of liga

29 ultra-high-affinity bidentate reagents, with equilibrium dissociation constants as low as 97 pM: >200

30 We also determined equilibrium dissociation constants as well as demonstrat

31 ilable receptor concentration divided by the equilibrium dissociation constant]) as the outcome measu

32 egative charge at the Q/R site increased the equilibrium dissociation constant at 0 mV (Kd(0)) for sp

33 as identical to a previously reported ligand equilibrium dissociation constant at rest and after acti

34 the KIX domain of the coactivator CBP, with equilibrium dissociation constants between 515 nM and 1.

35 t for the method was obtained by showing the equilibrium dissociation constant calculated from the ki

36 Specifically, we show that the equilibrium dissociation constant can be strongly affect

37 position 7 in the loop and the kinetics and equilibrium dissociation constants compared with the unm

38 st = rate constant for single turnover, KD = equilibrium dissociation constant) confirms vsr's prefer

39 (st)=rate constant for single turnover, K(D)=equilibrium dissociation constant) confirms vsr's prefer

40 d faster on-rates than RTO-PF4, and apparent equilibrium dissociation constants differed approximatel

41 The equilibrium dissociation constant for 1.3 kDa polyE bind

42 198F and epsilonD175N, by an increase in the equilibrium dissociation constant for ACh (KD) and a red

43 This allows the prediction of an equilibrium dissociation constant for all potential bind

44 retained, the K(m) for E1 decreased, and the equilibrium dissociation constant for ATP increased but

45 and we also use the arrays to determine the equilibrium dissociation constant for cholera toxin bind

46 The mean equilibrium dissociation constant for CsA (K(dCsA)) bind

47 d interfacial charge is characterized by the equilibrium dissociation constant for dissociation of th

48 The apparent equilibrium dissociation constant for extracellular Na(+

49 ate constant at saturation with Mn2+ and the equilibrium dissociation constant for Mn2+.

50 obic stopped-flow analyses revealed that the equilibrium dissociation constant for NADPH binding (K(d

51 actor, Sox2, decreases the exchange rate and equilibrium dissociation constant for Oct-1 > or = 5-fol

52 The apparent equilibrium dissociation constant for RcPRO1 binding to

53 The equilibrium dissociation constant for reversible binding

54 When K44 is mutated to alanine, the equilibrium dissociation constant for small unilamellar

55 Rather, the data suggest that the actual equilibrium dissociation constant for the alphaHL.

56 NR target operons, gives an estimate for the equilibrium dissociation constant for the binding of act

57 In the presence of excess chelator, the equilibrium dissociation constant for the binding of ami

58 The equilibrium dissociation constant for the binding of met

59 The equilibrium dissociation constant for the binding of pVI

60 In addition, the equilibrium dissociation constant for the binding of tSH

61 Between pH 4 and 8, the apparent equilibrium dissociation constant for the CcP(H52L)/cyan

62 However, the equilibrium dissociation constant for the enzyme in a st

63 The apparent equilibrium dissociation constant for the HER3-ECD self-

64 The apparent equilibrium dissociation constant for the inhibitor boun

65 The equilibrium dissociation constant for the interaction be

66 hanol (DMPM) vesicles is characterized as an equilibrium dissociation constant for the interfacial bi

67 The equilibrium dissociation constant for the substrate was

68 The equilibrium dissociation constant for the ternary comple

69 e device was used to successfully measure an equilibrium dissociation constant for Zn(2+) and human s

70 lower-affinity (LA) and higher-affinity (HA) equilibrium dissociation constants for acetylcholine in

71 The equilibrium dissociation constants for AdoMet, AdoHcy an

72 The results showed that the bulk solution equilibrium dissociation constants for anti-biotin and a

73 The equilibrium dissociation constants for Co2+ and Ni2+ act

74 arbohydrates, and (iii) measure the solution equilibrium dissociation constants for ConA and jacalin

75 From similar experiments, the equilibrium dissociation constants for dissociation of A

76 h provided semiquantitative estimates of the equilibrium dissociation constants for dissociation of B

77 Values for the equilibrium dissociation constants for high affinity bin

78 ounds, we present a protocol for determining equilibrium dissociation constants for HSA in a high-thr

79 The kinetic rate constants and equilibrium dissociation constants for monomeric and dim

80 el retardation assay was used to measure the equilibrium dissociation constants for the binding of an

81 The equilibrium dissociation constants for the binding of AV

82 The apparent equilibrium dissociation constants for the binding of bo

83 Equilibrium dissociation constants for the binding of th

84 rmined on- and off-rate constants along with equilibrium dissociation constants for the following ana

85 We show that the equilibrium dissociation constants for the interaction o

86 fluorescence anisotropy methods to determine equilibrium dissociation constants for the interaction o

87 They bound with high affinity: equilibrium dissociation constants for the three MAbs we

88 ociation and dissociation rate constants and equilibrium dissociation constants for thrombin.aptamer

89 SPR analysis yielded equilibrium dissociation constants for TnC (plus Ca(2+))

90 ple and convenient way of directly measuring equilibrium dissociation constants for very high affinit

91 netics, with HsY430A increasing the cofactor equilibrium dissociation constant from approximately 10

92 y 800 nM and TcY435A increasing the cofactor equilibrium dissociation constant from approximately 100

93 Receptor binding sites characterized by two equilibrium dissociation constants have been identified.

94 minus of Kv4.3 is calcium-dependent, with an equilibrium dissociation constant in the apo-state of 70

95 ensity of available receptors, and K(D), the equilibrium dissociation constant in the human brain, wi

96 of monomers and dimers in solution, with an equilibrium dissociation constant in the low micromolar

97 ces inclusive of both direct repeats, has an equilibrium dissociation constant in the nanomolar range

98 polypurine site in the supF target DNA, with equilibrium dissociation constants in the 10(-8) M range

99 strategy, the binding proteins isolated had equilibrium dissociation constants in the nanomolar to m

100 es form ion pairs in liquid ammonia, but the equilibrium dissociation constants indicate favorable in

101 We kinetically determined that the equilibrium dissociation constant is 190 nM with a disso

102 The oxygen equilibrium dissociation constant is approximately 1 nm

103 tetrachloride where the ethanol-cholesterol equilibrium dissociation constant is estimated to be 2 x

104 inding in an in vivo assay, but in vitro the equilibrium dissociation constant is significantly highe

105 Furthermore, the intrinsic equilibrium dissociation constant K(1) for hGluK2, like

106 e been evolved in vitro with antigen-binding equilibrium dissociation constant K(d) = 48 fM and slowe

107 s valid over the full range of values of the equilibrium dissociation constant K(D) and the other whi

108 to one molecule of the hexon trimer with an equilibrium dissociation constant K(d)((app)) of 1.1 nm.

109 An equilibrium dissociation constant K(D)(1) of 2.6 microM

110 ty for the peripheral site, indicated by the equilibrium dissociation constant K(S), from the depende

111 +/-0.7) x 10(-)(3) s(-)(1), and a calculated equilibrium (dissociation) constant (K(d)) of 1.5 (+/-0.

112 spectively, which corresponded to an average equilibrium dissociation constant (K(D) of 2.6+/-1.4 x 1

113 facile assay is described for measuring the equilibrium dissociation constant (K(d)) and dissociatio

114 onnexin43 (Cx43) gap junctions increased the equilibrium dissociation constant (K(d)) and reduced the

115 D25N) that may relate to the increase in the equilibrium dissociation constant (K(d)) and the very lo

116 d by ligand-binding activity, with a similar equilibrium dissociation constant (K(d)) for [(3)H]-mibo

117 e linear regime to the other occurs near the equilibrium dissociation constant (K(d)) for dNTP bindin

118 The equilibrium dissociation constant (K(d)) for the interac

119 ed aptamers can bind to target cells with an equilibrium dissociation constant (K(d)) in the nanomola

120 There was an apparent threshold at an equilibrium dissociation constant (K(d)) of 1 x 10(-)(7)

121 100-containing lipoprotein particles with an equilibrium dissociation constant (K(D)) of 17 nm and a

122 analysis of binding studies demonstrates an equilibrium dissociation constant (K(d)) of 27.6 nm.

123 o the fibrinogen-like domain of TN-C with an equilibrium dissociation constant (K(d)) of 5 x 10(-9) m

124 and 1.15 +/- 0.08 x 10(-6) s(-1) to give an equilibrium dissociation constant (K(D)) of approximatel

125 )), dissociation rate constant (k(off)), and equilibrium dissociation constant (K(D)) of chemically d

126 vestigations--that enables us to measure the equilibrium dissociation constant (K(D)) of recombinant

127 The apparent equilibrium dissociation constant (K(D)) of the vnd/NK-2

128 midinone analog, binds to the enzyme with an equilibrium dissociation constant (K(d)) of ~400 nM.

129 for AMPhe-Gly-Gly, which bound to Q7 with an equilibrium dissociation constant (K(d)) value of 0.95 n

130 tosamine (3'-SLN) and 6'-SLN sialosides with equilibrium dissociation constant (K(D)) values of 30.0

131 detected for oleic acid with a subnanomolar equilibrium dissociation constant (K(d)).

132 inhibitor of factor Xa (FXa) with a reported equilibrium dissociation constant (K(I)) of approximatel

133 Finally, equilibrium dissociation constants (K(b)) of selective a

134 o each studied antigen, we obtained apparent equilibrium dissociation constants (K(D) values) spannin

135 Equilibrium dissociation constants (K(d)'s) of the compo

136 ans [KCl] was systematically lowered and the equilibrium dissociation constants (K(d)) and kinetics o

137 us (SARS-CoV)-neutralizing antibody 80R with equilibrium dissociation constants (K(D)) as low as 37 p

138 protective antigen subunit of the toxin with equilibrium dissociation constants (K(d)) between 63 nM

139 ric studies reveal moderate decreases in the equilibrium dissociation constants (K(d)) for both ATP a

140 eparation performance allows quantitation of equilibrium dissociation constants (K(d)) for both rapid

141 oNT/A Lc yielded 15 yeast-displayed VHH with equilibrium dissociation constants (K(d)) from 230 to 0.

142 nity host-glycan:bacterial-glycan pairs with equilibrium dissociation constants (K(D)) ranging betwee

143 try was used to determine apparent gas-phase equilibrium dissociation constants (K(d)) values of 0.15

144 The apparent equilibrium dissociation constants (K(D)) were compared

145 Equilibrium dissociation constants (K(d)) were measured

146 on, making it possible to calculate apparent equilibrium dissociation constants (K(d)s) for NCPs reco

147 y interactions, such as SH2 and PTB domains, equilibrium dissociation constants (K(D)s) for their pep

148 A high inhibition potency (equilibrium dissociation constant [K(i)] = 2.34 +/- 2.94

149 independent of DNA sequence with an apparent equilibrium dissociation constant, K(d)((app)), of 46 nm

150 as 6-fold after replacing a single adenine (equilibrium dissociation constant, K(D), 5.3 nm) with an

151 The equilibrium dissociation constant, K(d), for the reversi

152 ent kinetic constants, k(on) and k(off), and equilibrium dissociation constant, K(d), have been deter

153 -based binding kinetic analysis indicated an equilibrium dissociation constant, K(d), of 54 nmol/L fo

154 nonspecific partitioning into the lipid, the equilibrium dissociation constant, K(d), of isoflurane b

155 The radiotracer equilibrium dissociation constant, K(D), was similar in

156 Herein, the apparent equilibrium dissociation constant, K(Dapp), between Cu(2

157 The apparent equilibrium dissociation constant, K(DApp), for the Cu(2

158 Microscopic equilibrium dissociation constants, k as, were determine

159 The affinities (equilibrium dissociation constants, K(d)) for the SAR-55

160 al binding sites on the cell surface, N, and equilibrium dissociation constants, K(nsL) and K(nsM), f

161 ) M(-1) s(-1), which correspond to acid-base equilibrium dissociation constants (Ka) in excellent agr

162 It showed an equilibrium dissociation constant (KB) of 167.3 nM with

163 sequences that can be used to calculate the equilibrium dissociation constant ( Kd ) from hybridizat

164 n primary bronchial epithelial cells with an equilibrium dissociation constant (Kd) = 9.8 nM and maxi

165 Equilibrium dissociation constant (KD) and maximum bindi

166 haracteristics, as indicated by the measured equilibrium dissociation constant (Kd) for the binding o

167 immunosorbent assay-type binding assay, the equilibrium dissociation constant (Kd) for the interacti

168 lated cell lines in variant patterns with an equilibrium dissociation constant (Kd) in the nanomolar

169 ERp5 binds to beta3 integrin with an equilibrium dissociation constant (KD) of 21 microM, mea

170 of HIG-82 cells bound 125I-IL-1beta with an equilibrium dissociation constant (Kd) of 67.3 +/- 7.8 p

171 Quantitative analysis yields an equilibrium dissociation constant (KD) of 777 +/- 93 nM

172 Equilibrium dissociation constant (Kd) values were calcu

173 g, and this observable was used to determine equilibrium dissociation constant (Kd) values.

174 o the high-affinity binding site of TTR with equilibrium dissociation constants (Kd values) in the lo

175 f) approximately 10(-4)-10(-3) s(-1); giving equilibrium dissociation constants (Kd) = 8-50 nM.

176 ent antibodies with over a four-log range of equilibrium dissociation constants (KD) and found that S

177 sed an approximately 40-fold decrease in the equilibrium dissociation constants (Kd) for ATP from app

178 rrays of the selected sequences and obtained equilibrium dissociation constants (Kd) for every aptame

179 e protection assay was used to determine the equilibrium dissociation constants (Kd) for the binding

180 y of high-affinity protein interactions with equilibrium dissociation constants (KD) in the picomolar

181 complexes formed in a 1:1 stoichiometry with equilibrium dissociation constants (Kd) of 50 +/- 10 nM

182 The melt experiments yielded equilibrium dissociation constants (Kd) ranging from 10(

183 , and Ab-labeled Dynabeads exhibited similar equilibrium dissociation constants (Kd), approximately 2

184 a carbohydrate-dependent affinity of rSodC (equilibrium dissociation constant [KD] = 0.862 muM) that

185 inity for Fn was very high for both FL-ScpB (equilibrium dissociation constant [KD] = 4.0 nM) and Scp

186 es obtained were V3 (receptor density [Bmax]/equilibrium dissociation constant [KD]), V3' (f1 x Bmax/

187 hesis that there are distinct high-affinity (equilibrium dissociation constant [KD], 20 microM) and l

188 67 cells revealed high-affinity LDL binding (equilibrium dissociation constant, Kd = 7 nM) and maximu

189 e literature, estimates of the monomer-dimer equilibrium dissociation constant, KD, have varied more

190 o determine the complex stoichiometry and an equilibrium dissociation constant, KD, of 100 nM.

191 of binding kinetics on a biosensor yields an equilibrium dissociation constant, KD, of 19.7 nM.

192 e S1 domain and bound S1 with high affinity (equilibrium dissociation constant, Kd=32.3 nM).

193 Fluorescence emission measurements of the equilibrium dissociation constants, Kd, of oxidized (hAR

194 The value of the equilibrium dissociation constant (KD1xKD2=1.64x10(-7) m

195 First, equilibrium dissociation constants (KDDNA) were determin

196 stent problem is that reported values of the equilibrium dissociation constants (Kds) of complexes of

197 it is optimal to use a binding moiety whose equilibrium dissociation constant matches that of the av

198 The equilibrium dissociation constant measured for LATB bind

199 Equilibrium dissociation constants measured for sequence

200 Surprisingly, equilibrium dissociation constants measured for the kina

201 Equilibrium dissociation constants obtained for the acti

202 tion of a 1:1 stoichiometric complex with an equilibrium dissociation constant of 0.2 to 0.4 micromet

203 ectively to the AChE peripheral site with an equilibrium dissociation constant of 1.0 microm.

204 transition state analogue inhibitor with an equilibrium dissociation constant of 1.0 nM.

205 loop results in a heterodimer with a subunit equilibrium dissociation constant of 1.32 +/- 1.25 micro

206 The BIACORE data show an equilibrium dissociation constant of 1.58 nM for the com

207 splayed high binding affinity to EphB4, with equilibrium dissociation constant of 1.98-23 nM.

208 plex approximately 700-fold, resulting in an equilibrium dissociation constant of 130 nM.

209 blocked by (-)-bupranolol (1 microM) with an equilibrium dissociation constant of 15 nM in WT and 17

210 ChIP3 in a calcium-dependent manner, with an equilibrium dissociation constant of 2-5 muM in the calc

211 odimer binds to the S15-rRNA complex with an equilibrium dissociation constant of 2.7 nM at 40 degree

212 escence anisotropy and providing an apparent equilibrium dissociation constant of 236 nm.

213 y of 1:1 for protein to DNA with an apparent equilibrium dissociation constant of 3.9 nM.

214 e-site binding model and yielded an apparent equilibrium dissociation constant of 334 +/- 23 nm.

215 endosomal PS, and we estimated an hsc-70/PS equilibrium dissociation constant of 4.7 +/- 0.1 mum.

216 affinity of the species B1 Ad16 fiber knob (equilibrium dissociation constant of 437 nM).

217 W1 and W2 each bound to PA with an equilibrium dissociation constant of 4x10-11 mol/L to 5x

218 been immobilized on plastic with an apparent equilibrium dissociation constant of 5 nM.

219 and 14-3-3zeta is of high affinity, with an equilibrium dissociation constant of 7 nM.

220 s a reversible monomer/dimer mixture with an equilibrium dissociation constant of 8.0 +/- 2.5 microM.

221 ht-binding inhibition with TvPNP, to give an equilibrium dissociation constant of 87 pM, an inhibitor

222 single protein-RNA complex with an apparent equilibrium dissociation constant of 9.0 x 10(-6) M.

223 An equilibrium dissociation constant of 92 nM for the p66/p

224 ed by experimental data that the value of an equilibrium dissociation constant of a binding peptide c

225 = NH4(+) > Cs(+) > Na(+)); and the apparent equilibrium dissociation constant of a single regulatory

226 ent energy donor and acceptor groups gave an equilibrium dissociation constant of about 0.8 microM(2)

227 s the data in the absence of tau, yields the equilibrium dissociation constant of approximately 2 mic

228 7.2, and we estimate an upper limit for the equilibrium dissociation constant of approximately 50 nM

229 Pase Rho3p in a GTP-dependent manner with an equilibrium dissociation constant of approximately 70 mi

230 on application of a pressure of 500 bar, the equilibrium dissociation constant of BamHI binding to th

231 e variants have substantial reduction in the equilibrium dissociation constant of binding (KD) of hMP

232 n encoded in the human genome to measure the equilibrium dissociation constant of each domain for 61

233 r distortion (isomerization) showed that the equilibrium dissociation constant of RNA polymerase-P1 c

234 Even for Ca(2+), however, the apparent equilibrium dissociation constant of the cation with the

235 The equilibrium dissociation constant of the dimeric clamp v

236 The equilibrium dissociation constant of the DNA binding dom

237 k(off) by a substrate-trapping approach, the equilibrium dissociation constant of the enzyme-DNA comp

238 Equilibrium dialysis demonstrated that the equilibrium dissociation constant of the flavopiridol-DN

239 These results suggest that the equilibrium dissociation constant of the LFA-1/ICAM-1 in

240 n chemosensory perception, we determined the equilibrium dissociation constant of the OBP-pheromone c

241 The equilibrium dissociation constant of the resting conform

242 beta(4) and profilin may greatly exceed the equilibrium dissociation constant of the ternary complex

243 ), 5.9 x 10(-3), and 1.9 x 10(-2) s(-1), and equilibrium dissociation constants of 0.72, 0.71, 0.56,

244 Eight analogues of ImmH are identified with equilibrium dissociation constants of 1 nM or below.

245 to protein A on disulfide monolayers yielded equilibrium dissociation constants of 1.4x10(-7)M.

246 s indicated that ECS binds antithrombin with equilibrium dissociation constants of 10.5 and 66 microM

247 ovalbumins in the intact form bind ANS with equilibrium dissociation constants of 116 and 125 microM

248 hat binds to mouse IgG1 and mouse IgG2a with equilibrium dissociation constants of 13.2 microM and 14

249 nfirm the 2:1 stoichiometry of binding, with equilibrium dissociation constants of 176 nM and 431 nM

250 r cytosine base at position 8 that result in equilibrium dissociation constants of 2.6 nM, 10 nM and

251 The equilibrium dissociation constants of 24B11 (KD = 4.2 x

252 omic-binding sites, we measured the in vitro equilibrium dissociation constants of 43 binding-site va

253 inus of the laminin-5 alpha(3) subunit, with equilibrium dissociation constants of 50 nm for plasmino

254 Respective equilibrium dissociation constants of 6 and 26 mM were o

255 nset, tight-binding inhibitors of MtPNP with equilibrium dissociation constants of 650, 42, and 24 pM

256 Equilibrium dissociation constants of anti-digoxin antib

257 The equilibrium dissociation constants of complexes of CRABP

258 We have measured the kinetic rates and equilibrium dissociation constants of IgG binding to a s

259 Collectively, the equilibrium dissociation constants of the soluble forms

260 The equilibrium dissociation constants of these peptide-pept

261 el retardation technique was used to measure equilibrium dissociation constants of this polymerase fo

262 Equilibrium dissociation constants of wild-type and base

263 2A interact with 1:1 stoichiometry at a KD (equilibrium dissociation constant) of 1.5 muM.

264 ain binds to three CD46 molecules with a KD (equilibrium dissociation constant) of 15.5 nM.

265 led a complex binding mechanism with a K(D) (equilibrium dissociation constant) of 150 nM +/- 70 nM.

266 the presence of RCC1, L binds Ran with a KD (equilibrium dissociation constant) of approximately 3 nM

267 Dependence of the equilibrium dissociation constant on the ionic strength

268 The low value of equilibrium dissociation constant or affinity unit (KD)

269 To identify the alpha(2)AR subtype involved, equilibrium dissociation constants (pK(b)) were determin

270 data, which have been used to determine the equilibrium dissociation constants, point to the loss of

271 The measurements of both equilibrium dissociation constants provided us with a th

272 Values of equilibrium dissociation constants ranged from 2 to 14 p

273 es of 223 unique molecular interactions with equilibrium dissociation constants ranging from 2 x 10(-

274 nge of antibody-ligand binding kinetics with equilibrium dissociation constants ranging from 200 pM t

275 okines binds EVM1 with 1:1 stoichiometry and equilibrium dissociation constants ranging from 29 pM to

276 dissociation and no measurable change in the equilibrium dissociation constant relative to that of th

277 nce-independent DNA-binding proteins with nm equilibrium dissociation constants such that in the viru

278 le binding site for betaCD, with an apparent equilibrium dissociation constant that varies by >100-fo

279 are not what one would expect based on their equilibrium dissociation constants; that the volume of a

280 nce quenches on the order of 6-15%, allowing equilibrium dissociation constants to be measured.

281 For the peptide Tyr-Leu-Ala, the equilibrium dissociation constant value is 7.2 nM, where

282 eoyl-sn-glycero-3-phosphocholine) yielded an equilibrium dissociation constant value of Kd = 180 +/-

283 At concentrations close to their equilibrium dissociation constant values, RIN1 and RAF1

284 E62 consensus binding sequence yielded K(D) (equilibrium dissociation constant) values in the nanomol

285 The dimer equilibrium dissociation constant was 0.25 microM in 0.0

286 In each case, the equilibrium dissociation constant was determined by foll

287 The secondary equilibrium dissociation constant was found to be the mo

288 In fact, the equilibrium dissociation constant was in the femtomolar

289 s sharply decreased by 10(3)-fold, while the equilibrium dissociation constant was weakened by nearly

290 By binding competition and determination of equilibrium dissociation constants, we show that Blimp-1

291 Lower limits to moenomycin off-rates and equilibrium dissociation constants were 7.7 x 10(-)(4) s

292 These equilibrium dissociation constants were based on the obs

293 polarization assay for these six AAAEs, and equilibrium dissociation constants were determined in di

294 Low nanomolar equilibrium dissociation constants were found for the ne

295 tein associates with HLA-A and -B molecules; equilibrium dissociation constants were in the nanomolar

296 A wide range of equilibrium dissociation constants were observed, and as

297 With this technique, equilibrium dissociation constants were quantified for p

298 The estimated equilibrium dissociation constants were virtually identi

299 n of rhodopsin to 11CR and opsin has a 25-pM equilibrium dissociation constant, which corresponds to

300 ly equal to the antibody-peptide fluorophore equilibrium dissociation constant, which is near one nan