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1 the development of anti-EHV-1 agents in the equine.
5 view and biological characterization of H3N8 equine and canine influenza viruses using various experi
7 ere numerous genetic differences between the equine and canine viruses, this variation did not result
8 e amount of test material for both rhPDGF-BB/equine and rhPDGF-BB/beta-TCP groups was comparable, but
10 firmed an electron transferase activity with equine and yeast cytochrome c, suggesting a conservation
11 deria mallei causes rapidly fatal illness in equines and humans when contracted by inhalation and als
14 inked sialic acid motif (SA2,3Gal) in avian, equine, and canine species; the alpha2,6-linked sialic a
15 e we characterize the replication of canine, equine, and human IAVs in the trachea of the dog, a spec
18 ALB/c mice were given up to 2 mg of purified equine antisera per animal, at 30 minutes, 1 or 2 days p
19 rease the possibility of serum sickness, the equine antisera was digested with pepsin to generate F(a
20 tential target of IgE-mediated reactivity to equine antivenom and a possible cause of the high incide
24 ro susceptibility of CD3(+) T lymphocytes to equine arteritis virus (EAV) infection and establishment
26 site, we determined the crystal structure of equine arteritis virus PLP2 in complex with ubiquitin (1
28 examined the potential of H3N8 from canine, equine, avian, and seal origin to productively infect pi
29 he gel coating reduced the immunogenicity of equine BChE, unlocking the possibility to use non-human
31 ection of H. capsulatum var. farciminosum in equine blood and at high frequency among horses exhibiti
32 hat is associated with the administration of equine blood products; its etiologic agent has remained
36 WT virus infection, IFN-beta mRNA levels in equine cells infected with PLP2 mutants were increased b
38 umulations of trophoblast cells that produce equine chorionic gonadotropin between days 40 and 120 of
39 In horses, the CXCL16 gene is located on equine chromosome 11 (ECA11) and encodes a glycosylated,
41 this study, we evaluated the ability of the equine clinical treatments N-acetylcysteine, EDTA, and h
43 on cold), human enteric coronavirus (HECoV), equine coronavirus (ECoV), and equine torovirus Berne (B
44 us studies in our laboratory have identified equine CXCL16 (EqCXCL16) to be a candidate molecule and
46 iation/association kinetics for yeast versus equine cytochrome c indicate that formation of mammalian
48 per day, intravenously, on days -4 to -2, or equine derived 30 mg/kg per day, intravenously, on days
51 e for association studies of immune-mediated equine diseases and for evolutionary analysis of genetic
53 ern equine encephalitis (EEE) and Venezuelan equine encephalitis (VEE) viruses are pathogens that inf
55 is, western equine encephalitis, and eastern equine encephalitis expressing the surface proteins of a
56 oly I:C) and a potential vaccine [Venezuelan equine encephalitis replicon particles expressing MERS-C
57 , or an unrelated, intramuscular, Venezuelan equine encephalitis replicon vaccine expressing EBOV GP.
58 EBOV glycoprotein (GP)-expressing Venezuelan equine encephalitis viral replicon particle vaccine prot
60 ghly pathogenic phenotype.IMPORTANCE Eastern equine encephalitis virus (EEEV) is one of the most path
61 equine encephalitis virus (WEEV), or eastern equine encephalitis virus (EEEV) when given individually
62 an equine encephalitis virus (VEEV), eastern equine encephalitis virus (EEEV), and western equine enc
63 equine encephalitis virus (WEEV) and eastern equine encephalitis virus (EEEV), two New World alphavir
64 equine encephalitis virus (VEEV) and Eastern equine encephalitis virus (EEEV), which have demonstrate
66 ycoprotein of natural North American eastern equine encephalitis virus (NA-EEEV) isolates and demonst
68 The genome from the alphavirus Venezuelan equine encephalitis virus (VEE) was modified to express
69 are the encephalitic alphaviruses Venezuelan equine encephalitis virus (VEEV) and Eastern equine ence
70 her related alphaviruses, such as Venezuelan equine encephalitis virus (VEEV) and Semliki Forest viru
71 usly, a replicon vaccine based on Venezuelan equine encephalitis virus (VEEV) demonstrated protective
73 teins of Sindbis virus (SINV) and Venezuelan equine encephalitis virus (VEEV) form cytoplasmic comple
85 we have developed a noncytopathic Venezuelan equine encephalitis virus (VEEV) mutant that can persist
86 The infectious titer of WNV and Venezuelan equine encephalitis virus (VEEV) TC83 in the brains of A
88 ins drive the assembly of vRCs of Venezuelan equine encephalitis virus (VEEV), and G3BPs were shown t
89 , Rift Valley fever virus (RVFV), Venezuelan equine encephalitis virus (VEEV), and herpes simplex vir
91 ocess of one of the alphaviruses, Venezuelan equine encephalitis virus (VEEV), to understand its adap
92 se severe encephalitis in humans: Venezuelan equine encephalitis virus (VEEV), western equine encepha
93 potential vaccine candidates for Venezuelan equine encephalitis virus (VEEV), western equine encepha
94 ics are currently unavailable for Venezuelan equine encephalitis virus (VEEV), which elicits flu-like
96 emonstrate that Tc bovine-derived Venezuelan equine encephalitis virus (VEEV)-specific TcPAbs are hig
98 rotropic alphaviruses, which include western equine encephalitis virus (WEEV) and Fort Morgan virus,
99 quine encephalitis virus (EEEV), and western equine encephalitis virus (WEEV) are arthropod-borne pos
102 an equine encephalitis virus (VEEV), western equine encephalitis virus (WEEV), and eastern equine enc
103 an equine encephalitis virus (VEEV), western equine encephalitis virus (WEEV), or eastern equine ence
105 o pathogenic mosquito-borne viruses (Eastern equine encephalitis virus [EEEV], Western equine encepha
106 equine encephalitis virus [WEEV], Venezuelan equine encephalitis virus [VEEV], and Chikungunya virus
107 rn equine encephalitis virus [EEEV], Western equine encephalitis virus [WEEV], Venezuelan equine ence
108 r atomic resolution structures of Venezuelan equine encephalitis virus and dengue virus revealed tran
110 er encephalitic arboviruses, such as eastern equine encephalitis virus and West Nile virus, underscor
111 very amino-terminal subdomain of Venezuelan equine encephalitis virus capsid protein, SD1, plays a c
113 IXV) is an enzootic member of the Venezuelan Equine Encephalitis Virus complex and belongs to the New
114 of the mosquito-borne North American eastern equine encephalitis virus in myeloid-lineage cells by bi
116 ase (PARP) family in clearance of Venezuelan equine encephalitis virus mutants from infected cells.
117 a virus-vectored vaccine (Kp47/47-Venezuelan equine encephalitis virus replicon particle) for safety,
118 opagating vaccine vector based on Venezuelan equine encephalitis virus replicon particles (VRP) expre
119 Using synthetic genomics and Venezuelan equine encephalitis virus replicons (VRPs) expressing sp
121 pagating, truncated derivative of Venezuelan equine encephalitis virus that targets dendritic cells (
122 n coronavirus 229E), Togaviridae (Venezuelan equine encephalitis virus), and Hepeviridae (HEV), indic
123 nly one other NT human arbovirus (Venezuelan equine encephalitis virus), which is also poorly underst
124 ing primary mosquito infection by Venezuelan equine encephalitis virus, an arbovirus causing neurolog
125 arations of bacteriophage lambda, Venezuelan equine encephalitis virus, and Staphylococcus aureus dur
126 lethal alphavirus infection with Venezuelan equine encephalitis virus, and this was associated with
127 he alphaviruses Sindbis virus and Venezuelan equine encephalitis virus, as well as La Crosse bunyavir
128 ellow fever virus, Sindbis virus, Venezuelan equine encephalitis virus, measles virus, influenza A vi
130 bis, Chikungunya, and eastern and Venezuelan equine encephalitis viruses and demonstrate that a small
132 halitic alphaviruses (eastern and Venezuelan equine encephalitis viruses) based upon either fusion of
133 , including western, eastern, and Venezuelan equine encephalitis viruses, cause serious and potential
134 for Venezuelan equine encephalitis, western equine encephalitis, and eastern equine encephalitis exp
135 ause Venezuelan equine encephalitis, western equine encephalitis, and eastern equine encephalitis.
136 seen with Japanese encephalitis, Venezuelan equine encephalitis, and Rift Valley fever viruses; and
137 developed a combined vaccine for Venezuelan equine encephalitis, western equine encephalitis, and ea
138 lenge with the viruses that cause Venezuelan equine encephalitis, western equine encephalitis, and ea
141 To characterize the role of biofilms in equine endometritis, six mares were inoculated with lux-
146 signment to hormone therapy (HT) (conjugated equine estrogen (CEE) alone or CEE plus medroxyprogester
147 with a uterus were randomized to conjugated equine estrogens (0.625 mg/d [estrogen]) plus medroxypro
148 ostmenopausal women to placebo or conjugated equine estrogens (0.625 mg/d) plus medroxyprogesterone a
149 ociations between the use of oral conjugated equine estrogens (CEE) (0.625 mg/day) plus medroxyproges
151 en with an intact uterus received conjugated equine estrogens (CEE; 0.625 mg/d) plus medroxyprogester
152 to receive 4 y of 0.45 mg/d oral conjugated equine estrogens (o-CEE) plus 200 mg/d micronized proges
154 r hysterectomy were randomized to conjugated equine estrogens alone (0.625 mg/d) or placebo with a me
155 ical significance in the trial of conjugated equine estrogens alone in women with prior hysterectomy
157 hey had a uterus (N=16 608) or to conjugated equine estrogens only if they had prior hysterectomy (N=
158 one, replication was not observed in primary equine fetal liver cultures or after electroporation of
160 V from different lineages and sublineages, A/equine/Georgia/1/1981 (eq/GA/81) was selected to produce
161 unt of new cementum formed for the rhPDGF-BB/equine group (4.8 +/- 1.3 mm) was significantly higher (
166 -as well as those from humans, swine and the equine H3N8 lineage--sharing an ancestor with them in th
168 l genomic segments and demonstrates that the equine H7N7 lineage is a sister clade to strains from bi
169 no acid sequence differences between the two equine HAs located on the virus membrane-distal molecula
172 e many animal and primate hepaciviruses, the equine hepaciviruses remain the closest genetic relative
173 the SRT of IE62 was replaced with the SRT of equine herpesvirus 1 (EHV-1) IEP, its trans-activation a
174 accination remains the best option to combat equine herpesvirus 1 (EHV-1) infection, and several diff
176 from herpes simplex virus type 1 (HSV-1) and equine herpesvirus type 1 (EHV-1) failed to support DNA
180 multiple introductions of MRSA CC398 in a UK Equine Hospital, identifying an emerging zoonotic pathog
187 Herein we describe production of purified equine IgG obtained from horses immunized with plasmid D
191 ift from the recommended polyclonal human or equine immunoglobulins to monoclonal antibody therapies.
192 ritis virus (EAV) has a global impact on the equine industry as the causative agent of equine viral a
193 source of significant economic loss for the equine industry from high rates of abortion in pregnant
195 genetic analyses of isolates from 2 cases of equine infection with the EEE virus and 1 case of human
198 f N-tropic murine leukemia virus (N-MLV) and equine infectious anemia virus (EIAV) infection, promoti
200 n we studied the full-length CA protein from equine infectious anemia virus (EIAV), a lentivirus shar
201 HIV-1, feline immunodeficiency virus (FIV), equine infectious anemia virus (EIAV), or N-tropic murin
205 humans; however, a recent report showed that equine influenza A viruses (IAVs) can be isolated from p
206 ne influenza virus (CIV) emerged from A/H3N8 equine influenza virus (EIV) around the year 2000 throug
211 , which originated from the transfer of H3N8 equine influenza virus to dogs; and the H3N2 CIV, which
212 04 an hemagglutinin 3 neuraminidase 8 (H3N8) equine influenza virus was transmitted from horses to do
214 ibution of K186 and E186 among H3N8 CIVs and equine influenza viruses (EIVs), the ancestors of H3N8 C
216 it is important to develop vaccines against equine influenza viruses in the event that an EIV evolve
217 and 16S rRNA gene sequence showed that most equine isolates could also be differentiated from S. dys
218 other antimicrobial agents against clinical equine isolates of Corynebacterium pseudotuberculosis.
219 lciforme strains (12/15) were recovered from equine keratitis infections; however, strains of F. kera
220 est the potential anti-rotavirus activity of equine lactadherin and support the feasibility of develo
222 s with prominent pigment synthesis mimicking equine melanoma represent a rare variant of biologically
223 ing (SAXS) was used to study the behavior of equine metmyoglobin (Mb) and bovine pancreatic trypsin i
224 .e., bovine pancreatic trypsin inhibitor and equine metmyoglobin, on the conformational ensemble of a
230 hat LukPQ is a potent and specific killer of equine neutrophils and identify equine-CXCRA and CXCR2 a
232 the symptoms of EEV can be similar to other equine notifiable diseases this is a significant finding
233 group and centre, to receive oral conjugated equine oestrogen (0.625 mg per day; n=5310) or matched p
234 hPDGF-BB) combined with either a particulate equine or a beta-tricalcium phosphate (beta-TCP) matrix.
236 f hydroxyapatite and collagen bone blocks of equine origin (eHAC), infused with recombinant human pla
237 ne influenza virus (CIV) H3N2 (CIV-H3N2) and equine-origin CIV H3N8 (CIV-H3N8), are enzootic in the c
238 respiratory disease in dogs, and include the equine-origin H3N8 and the avian-origin H3N2 viruses.
240 Experience with formulating guidelines for equine parasite control illustrates that end-users strug
241 ge of the vector ecology of these tick-borne equine pathogens, emphasizing tick transmissibility and
242 nalyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species withi
243 h most of these animals were coinfected with equine pegivirus (EPgV), also a flavivirus, EPgV viral l
249 l (GI) tracts of six species (bovine, ovine, equine, porcine, chicken, and deer) and from two human-d
250 ends decades of speculation, explaining how equine pregnancies survive without measurable circulatin
251 physiological concentrations and to maintain equine pregnancy in the absence of luteal progesterone i
254 circular virulence plasmids associated with equine (pVAPA) and porcine (pVAPB variant) R. equi isola
255 lance was implemented from 2011-2016 in a UK Equine Referral Veterinary Hospital and identified 81 me
257 roxide to disrupt in vitro biofilms and kill equine reproductive pathogens (Escherichia coli, Pseudom
258 ine respiratory mucosal explants and primary equine respiratory epithelial cells (EREC), grown at the
259 alphaherpesvirus family, was used to infect equine respiratory mucosal explants and primary equine r
260 ing specific nucleic acid sequences for four equine respiratory pathogens as representative examples,
261 cryo-electron microscopy structure of native equine rhinitis A virus (ERAV), together with the struct
262 ure of a unique, massively expanded state of equine rhinitis A virus that provides insight into how t
263 her we conducted a retrospective analysis of equine sera, which had been collected for diagnosis of o
266 -circulating bioscavenger nanogel by coating equine serum-derived BChE with a zwitterionic polymer ge
269 APL characteristics intermediate to those of equine SF from joints with acute injury and normal equin
270 on of high molecular weight HA (4,000 kd) to equine SF from joints with acute injury reduced the mu(k
275 and molecular weight, on the mu(kinetic) of equine SF samples from normal joints and joints with acu
281 e for gene flow involving three contemporary equine species despite chromosomal numbers varying from
282 vidual, woolly mammoths, polar bears and two equine species, we confirm that DNA methylation survives
283 ring tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), are hig
285 es, and to investigate the role of HA in the equine to canine cross-species transfer, we used X-ray c
286 irus (HECoV), equine coronavirus (ECoV), and equine torovirus Berne (BEV) are enzymatically active, r
287 y for the homologous protein of a torovirus, equine torovirus, which is more closely related to coron
290 hat Gram-negative bacteria isolated from the equine uterus are capable of producing a biofilm in vitr
292 gle nonantibiotic treatment commonly used in equine veterinary practice was able to reduce the CFU an
293 he equine industry as the causative agent of equine viral arteritis (EVA), a respiratory, systemic, a
294 In the fusion subdomain of canine and recent equine virus HAs a unique difference is observed by comp
298 antiviral activity of lactadherin sourced by equines, we undertook a proteomic analysis of milk fat g
299 -1 strain KyA is attenuated in the mouse and equine, whereas wild-type strain RacL11 induces severe i
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