ライフサイエンスコーパス: eradication

1 ize and invasiveness and could lead to tumor eradication.

2 nform strategies aimed at HIV prevention and eradication.

3 interest in regional elimination and global eradication.

4 ly eliminated diseases and even delay global eradication.

5 al latency of HIV is a last barrier to viral eradication.

6 criptional activation is dispensable for APL eradication.

7 re expected to lay the ground for future HBV eradication.

8 g interventions for reservoir containment or eradication.

9 herefore of primary importance to aim at CML eradication.

10 dered to be the last barrier towards malaria eradication.

11 n designing better interventions for poverty eradication.

12 e relation between resistance and first-line eradication.

13 lly reduced its spread and paved the way for eradication.

14 ervoirs, posing a significant barrier to HIV eradication.

15 ently no clinically indicated drug for their eradication.

16 s endgame and efforts to ensure global polio eradication.

17 drugs can significantly increase tumor cell eradication.

18 ces for climate targets of achieving poverty eradication.

19 curative therapeutic approaches based on LSC eradication.

20 h efficacy suggest their potential for HIV-1 eradication.

21 , which represent the major barrier to virus eradication.

22 traditional regimens and reduces the time to eradication.

23 t was performed 6 months after successful HP eradication.

24 f antibiotic used while maximising bacterial eradication.

25 s we approach the endgame strategy for polio eradication.

26 g global dialogue on malaria elimination and eradication.

27 in the Ras pathway but rarely leads to tumor eradication.

28 ulators, p53 and c-Myc, may facilitate their eradication.

29 trategies to achieve progress toward malaria eradication.

30 disease caused by PV and is on the verge of eradication.

31 or Alzheimer's disease, cancer, and HIV/AIDS eradication.

32 adication treatment and underwent successful eradication.

33 remains the most significant obstacle to HIV eradication.

34 It has brought polio to the brink of eradication.

35 vaccine-derived polioviruses threaten polio eradication.

36 cognate CD8(+) T cells contributed to tumor eradication.

37 cts in long-term vaccine success and disease eradication.

38 ate progress towards measles elimination and eradication.

39 control and may support protocols for HIV-1 eradication.

40 tric findings on VCE were not impacted by HP eradication.

41 perior path to cell-mediated HIV control and eradication.

42 uced in mass campaigns to help achieve polio eradication.

43 ning immunization programs, other than polio eradication.

44 sembly declared the completion of poliovirus eradication a programmatic emergency for global public h

45 only few antibiotics result in an effective eradication, a successful antibiotic driven worldwide er

46 ese strategies are targeted to lead to viral eradication--a cure for AIDS.

47 treated with the SOF-based regimen, with HCV eradication achieved, but became reinfected with a diffe

48 olio Eradication Initiative (GPEI) for polio eradication activities (hereafter, "GPEI-funded personne

49 New HPs reported here demonstrate potent eradication activities (MBEC = 0.59-9.38 microM) against

50 killed and deployable workforce to implement eradication activities across the globe.

51 y volunteers have provided support for polio eradication activities and continue to this day by makin

52 ersus the susceptible individuals on disease eradication affords critical policy insights.

53 nt (policy and technical) documents on polio eradication, along with minutes and reports from countri

54 ETBF eradication also significantly decreased mucosal IL-17A

55 tal in the effort toward disease control and eradication, an undertaking aided by an increased unders

56 ents and immunization professionals to polio eradication and an exemplary partnership between the WHO

57 rus (PV) is currently targeted for worldwide eradication and containment.

58 The Polio Eradication and Endgame Strategic Plan (PEESP) establish

59 io vaccine (IPV) as part of the Global Polio Eradication and Endgame Strategic Plan (the Endgame plan

60 The Polio Eradication and Endgame Strategic Plan 2013-2018 (Endgam

61 olio vaccine (OPV) associated with the Polio Eradication and Endgame Strategic Plan 2013-2018 began w

62 The Global Eradication and Endgame Strategic Plan 2013-2018 called

63 The Polio Eradication and Endgame Strategic Plan 2013-2018 calls f

64 The Polio Eradication and Endgame Strategic Plan 2013-2018 was dev

65 rdinate and oversee objective 2 of the Polio Eradication and Endgame Strategic Plan 2013-2018, namely

66 requirements under objective 2 of the Polio Eradication and Endgame Strategic Plan 2013-2018-to intr

67 The Polio Eradication and Endgame Strategic plan outlines the phas

68 cessary financial resources within the Polio Eradication and Endgame Strategic Plan timelines.

69 tners to national staff as part of the Polio Eradication and Endgame Strategic Plan, 2013-2018.

70 and coordination of Objective 2 of the Polio Eradication and Endgame Strategic Plan.

71 the absorbed dose levels required for tumor eradication and growth monitoring, as well as to evaluat

72 augmented by anti-CTLA-4 Ab to achieve tumor eradication and immunological memory.

73 n non-Hodgkin's lymphoma showed cancer cells eradication and long-term survivors.

74 Complete malaria eradication and optimal use of transmission-reducing int

75 ctively advocate for malaria elimination and eradication and outline key operational, technical, and

76 hum fields in Israel, leading to measures of eradication and quarantine.

77 n domain significantly enhanced both biofilm eradication and the ability to kill intracellular S. aur

78 rporate important lessons learned from polio eradication, and polio resources are concentrated in the

79 ne health-care worker screening and S aureus eradication are controversial.

80 ontrol agents for the end game of poliovirus eradication are discussed.

81 sporadic and limited, the impacts of global eradications are likely greater than we report here.

82 emand and trust for the last stages of polio eradication, as well as for other life-saving health int

83 nd international advocacy programs for polio eradication, assisting at immunization posts and clinics

84 bined symptomatic resolution/microbiological eradication at test of cure (TOC): 280 of 393 (71.2%) vs

85 Eradication attempts often involve removal of host plant

86 rawn upon when bOPV is withdrawn after polio eradication but also could be relevant for other global

87 ll OPVs are completely withdrawn after polio eradication, but also may offer a useful model for other

88 uccess of any treatment may well rest on CSC eradication, but specific anti-CSC therapies are still l

89 program and how it has contributed to polio eradication by building global public health workforce c

90 eir virulence and fitness program to prevent eradication by the host.

91 suppressive mechanism by which cancer avoids eradication by the immune system.

92 use immune evasion strategies to avoid their eradication by the immune system.

93 ies that may maximize target recognition and eradication by the sequential activation of a reconstitu

94 y the mechanisms of incomplete leukemic cell eradication by vemurafenib and to explore chemotherapy-f

95 in clinical development directed at HIV/AIDS eradication, cancer immunotherapy, and the treatment of

96 al Commission for the Certification of Polio Eradication certified the eradication of type 2 wild pol

97 Minimal biofilm eradication concentration (MBEC) was determined for 2- a

98 coverage represents the root cause of polio eradication delays.

99 ective vaccines remain sought for continuing eradication effort.

100 Eradication efforts for vaccine-preventable diseases nee

101 Global poliovirus eradication efforts include high vaccination coverage wi

102 sential for success, malaria elimination and eradication efforts will ultimately be driven at the cou

103 For A. petiolata, simulations suggest that eradication efforts would require unrealistic efficiency

104 c health workforce capacity to support polio eradication efforts, including national STOP programs.

105 s interventions, in collaboration with other eradication efforts, these high-risk pockets witnessed a

106 ively target the latent reservoir to enhance eradication efforts.

107 has emerged as a target for intervention in eradication efforts.

108 interest and may be of significance to HIV-1 eradication efforts.

109 ations for other vaccine-preventable disease eradication efforts.

110 eria has been the focus of intensified polio eradication efforts.

111 d to a global public health issue, the polio eradication Endgame plan.

112 munization-system strengthening in the Polio Eradication Endgame Strategic Plan 2013-2018 (PEESP), th

113 th goals in ten focus countries of the Polio Eradication Endgame Strategic Plan: policy & strategy de

114 (IPV) represents a crucial step in the polio eradication endgame.

115 A major approach to HIV eradication envisions antiretroviral suppression, paired

116 cure and sustain the enormous gains of polio eradication forever.

117 vide a promising step toward the goal of HIV eradication from the body.

118 hat a complete sterilizing cure, i.e., viral eradication from the host, is unlikely to be feasible.

119 re did not change significantly following HP eradication, Gastric findings on VCE were not impacted b

120 le diseases that will endure after the polio eradication goal is achieved.

121 d of drug resistance and threatens long-term eradication goals.

122 A key strategy for polio eradication has been the development of a skilled and de

123 tems are critical for all programs and polio eradication has illustrated these can be leveraged to in

124 ides a substantial challenge to global polio eradication, having contributed to 73% of reported polio

125 ion after frontline Helicobacter pylori (HP) eradication (HPE).

126 e (GPEI) in certifying and maintaining polio eradication in a standardized, ongoing, and credible man

127 The magnitude of benefit of H pylori eradication in populations with different levels of gast

128 inated across tissues and required for tumor eradication in several immunotherapy models.

129 effective and long-lasting tumor regression/eradication in subcutaneous and intraperitoneal xenograf

130 The overview reported HCV eradication in up to 98% for SOF/DCV and 96% for SOF/SIM

131 n Africa that have benefitted from the polio eradication infrastructure.

132 nnel receiving funding from the Global Polio Eradication Initiative (GPEI) for polio eradication acti

133 The Global Polio Eradication Initiative (GPEI) has been in operation sinc

134 ndependent bodies to assist the Global Polio Eradication Initiative (GPEI) in certifying and maintain

135 setbacks in the 28 years of the Global Polio Eradication Initiative (GPEI), this article articulates

136 fundamental cornerstone of the global polio eradication initiative (GPEI).

137 y as procurement agency for the Global Polio Eradication Initiative and Gavi, the Vaccine Alliance, U

138 human resources and their role in the Polio Eradication Initiative and in RI.

139 lia developed draft plans to integrate Polio Eradication Initiative assets, staff, structure, and act

140 Systems Management Group of the Global Polio Eradication Initiative has been useful to the NVI proces

141 The Global Polio Eradication Initiative has built an extensive infrastruc

142 Despite major setbacks, the Global Polio Eradication Initiative has made substantial progress in

143 The Global Polio Eradication Initiative has reduced the global incidence

144 gic Plan 2013-2018 (PEESP), the Global Polio Eradication Initiative identified 1 indicator: 10% annua

145 The Polio Eradication Initiative in Nigeria, which started >20 yea

146 P) program began supporting the Global Polio Eradication Initiative in the Republic of South Sudan to

147 As the global polio eradication initiative prepares to cease use of oral pol

148 in implementing the switch, the Global Polio Eradication Initiative provided catalytic financial supp

149 the key criteria prompting the Global Polio Eradication Initiative to begin withdrawal of oral polio

150 demonstrating the value of the Global Polio Eradication Initiative's legacy.

151 Health Assembly established the Global Polio Eradication Initiative, which consisted of a partnership

152 urate laboratory results to the Global Polio Eradication Initiative.

153 timal assay to measure HIV reservoirs in HIV eradication interventions.

154 Malaria eradication is a global health priority, but current the

155 However, successful H. pylori eradication is a more important factor for GU healing th

156 Significant tumor reduction or eradication is accomplishable by recruiting cytotoxic T

157 After eradication is achieved, what should happen to the subst

158 Poverty eradication is also the first of the Sustainable Develop

159 sm to ablate transferred T cells after tumor eradication is complete to allow recovery of normal B ce

160 infection occurring upon commensal bacteria eradication is efficiently overturned by mono-colonizati

161 The mission for HCV eradication is far from accomplished.

162 Measles and rubella eradication is feasible and cost saving.

163 However, poliovirus eradication is hampered globally by epidemics of vaccine

164 However, tumor eradication is rare, and duration of treatment response

165 One major barrier to eradication is that the virus infects multiple cell type

166 A significant challenge to HIV eradication is the elimination of viral reservoirs in ge

167 novel interventions are necessary if malaria eradication is to be achieved.

168 Current eradication measures rely on the rapid clinical detectio

169 ients as the parasite can be exterminated by eradication measures to avoid further incidents.

170 vimentin, presumably as part of a senescence eradication mechanism that may become impaired with age

171 Eradication occurred more rapidly in the 1-week group (1

172 analysis revealed that failure of H. pylori eradication (Odds = 4.013, 95% CI: 1.840-8.951, P < 0.00

173 mallpox vaccine, which has enabled the first eradication of a human viral pathogen and is a useful mo

174 /mTOR inhibitor gedatolisib resulted in near eradication of ALL in cytokine receptor-like factor 2 (C

175 pensatory events and thereby further enhance eradication of AML cells.

176 ts with blood disorders is safe and promotes eradication of ARB from the gastrointestinal tract.

177 acid drug, N-acetyl-L-cysteine (NAC), on the eradication of biofilms formed by the mucoid strain of P

178 mBiNE) to promote selective, immune-mediated eradication of cancer cells.

179 genous leukemia (CML) largely depends on the eradication of CML leukemic stem cells (LSCs).

180 Aggressive strategies, such as eradication of CML stem cells with limited duration and

181 ibitors may potentially lead to the complete eradication of CML stem cells.

182 ated immunity to assist in the detection and eradication of CML stem/progenitor cells.

183 ntigen seroclearance) and complete cure (ie, eradication of covalently closed circular DNA) of CHB, s

184 CNS relapse should concentrate on effective eradication of disease from this site rather than target

185 populations has applications in agriculture, eradication of disease vectors, control of invasive spec

186 velopment of chemotherapies to assist in the eradication of diseases caused by these pathogens.

187 mAb were tested for selective targeting and eradication of double-positive human NCI-H358 non-small

188 rococcal colonization of the gut can lead to eradication of enterococci.

189 ly injected tumor masses, achieving complete eradication of established disease has proven difficult.

190 e gastric cancer incidence, individuals with eradication of H pylori infection had a lower incidence

191 of SRs of pharmacological therapies for the eradication of H.pylori.

192 Our data suggest that eradication of HCV in coinfected patients is associated

193 Eradication of HCV infection improved cognitive performa

194 MC usually regresses after eradication of HCV with interferon, whose immunomodulato

195 rising incidence of this coincides with the eradication of Helicobacter pylori, both of which might

196 Eradication of hepatitis C virus (HCV) using direct-acti

197 In the quest for a functional cure or the eradication of HIV infection, it is necessary to know th

198 The principal barrier to the eradication of HIV/AIDS is the existence of latent viral

199 A notable exception was the eradication of human smallpox by vaccination over 30 yea

200 Current barriers to eradication of incident HBV infections via MTCT include

201 notypes as determined by sequencing with the eradication of infection was 86%.

202 therapies are being developed to accelerate eradication of infection, prevent new drug resistance, a

203 ndations that require ongoing commitments to eradication of infectious disease and increase the empha

204 ent has focused on detection, treatment, and eradication of infectious diseases such as tuberculosis,

205 ti-PD-1, and anti-CTLA-4 results in complete eradication of injected and noninjected subcutaneous tum

206 's esophagus (BE) with dysplasia is complete eradication of intestinal metaplasia (CEIM).

207 Patients who have achieved complete eradication of intestinal metaplasia should undergo surv

208 tent LGD with the goal of achieving complete eradication of intestinal metaplasia.

209 richness in the fecal material, resulting in eradication of Klebsiella pneumoniae compared with nonre

210 milar pMHC and pMHC-TCR affinity, results in eradication of large, established tumors when targeting

211 Eradication of leukemia stem cells (LSCs) is the ultimat

212 ment combined with anti-PD-L1 results in the eradication of light-irradiated primary tumors and the c

213 esents a major advance towards the effective eradication of malignant tumors.

214 This complex connection renders eradication of measles challenging in China despite its

215 ntities and identifies novel targets for the eradication of MYC-driven tumors.

216 e its use as the smallpox vaccine led to the eradication of one of the world's greatest killers.

217 FMT is effective in the eradication of pathogenic antibiotic-resistant organisms

218 ised and developing worlds shadows the rapid eradication of pathogens, such as parasitic helminths.

219 buted more than $1.61 billion for the global eradication of polio and has committed to provide an add

220 r the ultimate disposal of all OPV after the eradication of polio.

221 obal Commission for the Certification of the Eradication of Poliomyelitis certified the eradication o

222 cy of the polio program will be the complete eradication of poliovirus and the elimination of polio f

223 Eradication of poliovirus from endemic countries relies

224 ines, will be a major step towards the final eradication of poliovirus.

225 al therapy, we were able to achieve complete eradication of primary treated tumors and distant untrea

226 Primary outcome measure was eradication of seeds and globe salvage.

227 Having observed complete eradication of solid tumor xenografts, we conclude that

228 Eradication of systemic tuberculosis (TB) has been limit

229 Eradication of the bacteria did not significantly change

230 gin, demonstrating that transmission barrier eradication of the originating prions was ephemeral and

231 pment of antiretroviral therapy against HIV, eradication of the virus from the body, as a means to a

232 weapon for elimination of infected cells and eradication of the virus.

233 We have to accept that eradication of this infection is a two-edged sword that

234 urces have been devoted to the treatment and eradication of those diseases.

235 e Eradication of Poliomyelitis certified the eradication of type 2 poliovirus in September 2015, maki

236 The eradication of type 2 poliovirus, the absence of detecti

237 ification of Polio Eradication certified the eradication of type 2 wild poliovirus, 1 of 3 wild polio

238 es (CTL) play a potentially critical role in eradication of viral reservoirs, the features that const

239 20% and 30% OFSP flour could be used for the eradication of vitamin A deficiency as they were found t

240 is finding supports the WHO strategy for the eradication of yaws based on mass administration of the

241 disease, and to assess the influence of its eradication on disease activity and endoscopic and labor

242 The influence of HP eradication on disease activity was assessed.

243 udies to investigate the effects of H pylori eradication on the incidence of gastric cancer.

244 With global malaria eradication on the international agenda, malaria control

245 sed to greater effect toward achieving viral eradication or a functional cure.

246 Because monitoring of eradication outcomes is sporadic and limited, the impact

247 us type 2 during the next phase of the polio eradication plan.

248 and we should therefore focus our H. pylori eradication policy toward selectively identify and destr

249 This eradication prevented bacterial translocation, significa

250 regarding their antibacterial and bacterial eradication profiles.

251 on, a successful antibiotic driven worldwide eradication program seems unlikely.

252 infectious disease eradiation, the Smallpox Eradication Programme, utilized mass immunization using

253 Therefore, eradication programs must be specifically designed depen

254 help guide disease control, elimination, and eradication programs, these global networks provide capa

255 Eradication provided significant benefit for asymptomati

256 th-based therapy achieved similar or greater eradication rate compared to clarithromycin-based therap

257 The eradication rate obtained with Clarithromycin-based sequ

258 Viral eradication rates are pushing 100% for many HCV-infected

259 iagnosed as H.pylori infected and pooled the eradication rates in a meta-analysis.

260 Helicobacter pylori eradication rates in Portugal are declining, due to incr

261 primary antibiotic resistance and first-line eradication rates.

262 Current strategies for HIV-1 eradication require the reactivation of latent HIV-1 in

263 Achieving and maintaining eradication requires addressing the weakest links, which

264 tiple disciplines are engaged in the Malaria Eradication Research Agenda (malERA) Refresh process to

265 establishment can improve early-warning and eradication schemes.

266 ance (ES) of poliovirus in the poliomyelitis eradication strategic plan as an activity that can compl

267 al measles and rubella elimination and polio eradication strategies.

268 yaws is a crucial component of the WHO yaws eradication strategy to prevent relapse and the resultin

269 between the "kick" and "kill" steps of this eradication strategy.

270 esting CD4(+) T cells is essential for HIV-1 eradication studies.

271 known low clarithromycin resistance or high eradication success with these regimens.

272 enterologist in group B were associated with eradication success.

273 ne-week ligation intervals led to more rapid eradication than 2-week intervals without an increase in

274 tion of novel yet unproven approaches to HIV eradication that could compromise the health status of H

275 Importantly, after successful HP eradication, the immunoreactivity of the studied paramet

276 providing perspectives on possible H. pylori eradication therapies.

277 astric cancer than those who did not receive eradication therapy (pooled incidence rate ratio = 0.53;

278 re and specific, updated recommendations for eradication therapy in adults.

279 Practice Advice 11: Endoscopic eradication therapy should be considered in patients wit

280 ce Advice 14: Patients completing endoscopic eradication therapy should be enrolled in an endoscopic

281 dergoing surveillance rather than endoscopic eradication therapy should undergo surveillance every 6

282 Practice Advice 15: Following endoscopic eradication therapy, the biopsy protocol of obtaining bi

283 ion, both of which are key outcomes in HIV-1 eradication therapy.

284 Given the momentum gained toward polio eradication, these resources seem well positioned to hel

285 ric cancer (GC) remains even after H. pylori eradication; thus, other combination treatments, such as

286 ars has dramatically enhanced rates of viral eradication to >90% in patients with chronic hepatitis C

287 e for a strategy of early posttransplant HCV eradication to facilitate use of HCV+ organs whenever po

288 Polio; eradication; transmission; heterogeneity.

289 All HP positive patients were offered eradication treatment and underwent successful eradicati

290 Patients infected with HP were offered eradication treatment with sequential therapy.

291 tis changes; 3) patients receiving H. pylori eradication triple therapy and 8 weeks of maintenance th

292 but could be useful in conjunction with MeV eradication vaccine programs and as a safeguard in oncol

293 HP eradication was confirmed using urease breath test and s

294 Eradication was confirmed with urea breath test.

295 The overall undiscounted cost of eradication was estimated as $3.1 billion, and the benef

296 abled implementation of the endgame of polio eradication which calls for a phased withdrawal of oral

297 The partnerships that helped support polio eradication will need to consider funding to maintain an

298 Malaria eradication will require a combination of vector control

299 D-1 blockade has been shown to mediate tumor eradication with impressive clinical results.

300 ore recently, studies indicate that pathogen eradication within the CNS may require immune responses

301 cell depletion with optimal timing after AML eradication would preserve leukemia remission and allow