ライフサイエンスコーパス: erasure

1 y, arise from exactly the opposite model for erasure.

2 nges including DNA demethylation and imprint erasure.

3 d selectively, because dopamine blocks their erasure.

4 and infralimbic (IL) cortex to prevent fear erasure.

5 hey are downstream consequences of H2AK119Ub erasure.

6 reorganization, X reactivation, and imprint erasure.

7 printed genes remain relatively resistant to erasure.

8 d accounts for the unique process of imprint erasure.

9 eservoirs by performing perfect non-Landauer erasure.

10 g to chromatin, whereas ACF will not support erasure.

11 Differentiating between extinction and erasure accounts is extremely difficult and requires man

12 work cost applies for classical and quantum erasure alike.

13 te of the brain, constantly promoting memory erasure and competing with processes that promote memory

14 images implies an active mechanism of image erasure and creation as the basis of normal visual proce

15 reprogram their epigenomes via a genome-wide erasure and de novo rewriting of DNA methylation marks.

16 ood process of germ cell allocation, imprint erasure and gamete formation, with 4-6 weeks being requi

17 m switch of TET1 regulates epigenetic memory erasure and mouse development.

18 Erasure and subsequent reinstatement of DNA methylation

19 esults reveal a molecular mechanism for fear erasure and the relative instability of recent memory.

20 ting time, hours of image persistence, rapid erasure, and large area-a combination of properties that

21 act in 8.5- to 9.5-dpc PGCs and then undergo erasure at approximately 10.5 dpc as the PGCs enter the

22 show no evidence of DNA methylation imprint erasure at the cis-acting PSW imprinting center.

23 ctivating a fear memory results in effective erasure by subsequent extinction training.

24 s, quantum-limited amplifiers, dephasing and erasure channels in arbitrary dimension.

25 erest, including dephasing, depolarizing and erasure channels.

26 ectors and has a variety of implications for erasure coding, compressed sensing, and sparse recovery.

27 challenges in making inferences about memory erasure during extinction.

28 These results suggest that imprinting erasure during reprogramming depends on the epigenetic l

29 Whole genome profiling showed an erasure effect of IL-1beta and TNF-alpha, resulting in a

30 n two phase 3, double-blind, 52-week trials, ERASURE (Efficacy of Response and Safety of Two Fixed Se

31 s that this should produce persistent memory erasure even after the inhibitory agent is removed.

32 This contrasts with information erasure, first investigated by Landauer, for which a the

33 memories in juvenile rodents are subject to erasure following extinction training, while after closu

34 In females, erasure follows loss of X inactivation, causing X dosage

35 havior, which suggests that emotional memory erasure has occurred.

36 tus of PGCLCs resembles the dynamics of 5meC erasure in embryonic PGCs remains controversial.

37 diated pluripotent reprogramming and imprint erasure in somatic cells.

38 A closer look at H19 ICR revealed complete erasure in SSCiPSC in contrast to fiPSC.

39 Imprinting erasure in SSCiPSC was maintained even after in vivo dif

40 Here, we report that ALKBH5-mediated m6A erasure in the nuclei of spermatocytes and round spermat

41 f PGCLCs in studying the germline epigenetic erasure including imprinted genes, epimutations, and era

42 the energy dissipation in the memory during erasure is the most essential dissipation process in a d

43 at a central component of extinction-induced erasure is the synaptic removal of calcium-permeable alp

44 Conversely, in males, erasure leads to permanent X dosage decompensation.

45 In this setting of shared physiologic erasure, NSEs harbor a malignancy-associated hypermethyl

46 Erasure occurred without displacing the transcription fa

47 ly in renal development, followed by imprint erasure, occurs during Wilms' tumourigenesis.

48 lecular requirements, rather than simply the erasure of a previously learned process.

49 evelopment and in cloned animals, and in the erasure of acquired epigenetic information.

50 lencing machinery and its DUB partner allows erasure of active PTMs and the de novo transition of a t

51 ternally, both deletions are associated with erasure of all maternal GNAS methylation imprints and au

52 ications include, genome-wide demethylation, erasure of allele-specific methylation associated with i

53 y of PGCs showed nearly complete or complete erasure of allele-specific methylation in both H19 and S

54 cell mass, whereas others may require active erasure of chromatin marks.

55 tic tissues of the flower, necessitating the erasure of chromatin modifications that have accumulated

56 This produced persistent erasure of conditioned place avoidance.

57 the disorder may result from the progressive erasure of cortically based memory representations.

58 Here, we demonstrate that erasure of CpG methylation (5mC) in PGCs occurs via conv

59 fferentiation to memory cells was coupled to erasure of de novo methylation programs and re-expressio

60 Genome-wide erasure of DNA cytosine-5 methylation has been reported

61 Erasure of DNA methylation and repressive chromatin mark

62 ic reprogramming steps, including the global erasure of DNA methylation at the 5-position of cytosine

63 Although global erasure of DNA methylation has been observed in zygotes

64 genomic regions are resistant to widespread erasure of DNA methylation in mouse embryonic stem cells

65 Our results reveal that erasure of DNA methylation in the germ line is a global

66 AID deficiency interferes with genome-wide erasure of DNA methylation patterns, indicating that AID

67 Genome-wide erasure of DNA methylation takes place in primordial ger

68 The mechanisms of genome-wide erasure of DNA methylation, which involve modifications

69 network and progressive and conserved global erasure of DNA methylation.

70 osine, potential intermediates in the active erasure of DNA-methylation marks.

71 gramming involves processes that lead to the erasure of epigenetic information, reverting the chromat

72 Erasure of epigenetic memory is required to convert soma

73 ng specification of PGCs that results in the erasure of epigenetic memory of EpiSCs following reactiv

74 t stem cells synergistically and enhance the erasure of epigenetic memory.

75 of pluripotency-specific genes and extensive erasure of epigenetic modifications.

76 ypothesis that extinction causes the partial erasure of fear memories remains viable.

77 report that Tet1 has a critical role in the erasure of genomic imprinting.

78 tablishes a critical function of Tet1 in the erasure of genomic imprinting.

79 gratory primordial germ cells coincides with erasure of genomic imprints and reactivation of the inac

80 oietic precursor cell line results in global erasure of H2AK119Ub, striking depletion of H3K27me3, se

81 erve as a stable epigenetic memory, and that erasure of H3K4me2 by LSD/KDM1 in the germline prevents

82 Signal-dependent erasure of H4K20me3 is required for effective gene activ

83 ependent JMJD6 recruitment on A-PEs mediates erasure of H4R3me(2(s)), which is directly read by 7SK s

84 mmatory responses by altering the reading or erasure of histone modifications required for inflammato

85 f genomic imprinting, cell lineage-dependent erasure of imprinting, an unidentified mechanism of X ch

86 d in early embryos, and is important for the erasure of imprints and epimutations, and the return to

87 s Tet1 and Tet2 participate in the efficient erasure of imprints in this model system.

88 donors, and revealed that demethylation, or erasure of imprints, was already initiated in PGCs at 10

89 ng slow-wave sleep, leading to the selective erasure of information from hippocampal circuits as memo

90 e two key features, together with stochastic erasure of intervening stop codons, resulted in a unique

91 rrier progressively as they proceed with the erasure of key properties of epiblast cells, resulting i

92 ated that deterministic, nonvolatile writing/erasure of large-area patterns of this electromechanical

93 Most generally, TGCTs conserve PGC-lineage erasure of maternal and paternal genomic imprints and DP

94 In AD, such a rapid erasure of memories soon after they are acquired during

95 We show here that erasure of methylation marks during male germ-line devel

96 Wild-type PGCs revealed marked genome-wide erasure of methylation to a level below that of methylat

97 Conversely, erasure of methylation was observed at the identified CG

98 Here, we report the creation and erasure of nanoscale conducting regions at the interface

99 ntenance of some of these modifications, but erasure of others.

100 in this context is DNA demethylation and the erasure of parental imprints in mouse primordial germ ce

101 c, most PGCs did not demonstrate significant erasure of paternal allele-specific methylation until 10

102 evidence supporting the role of Tet1 in the erasure of paternal imprints in the female germ line.

103 ing chromatin state was achieved by specific erasure of preexisting chromatin marks in the precursor

104 ear architecture accompanied by an extensive erasure of several histone modifications and exchange of

105 golith layer, as well as the degradation and erasure of small impact craters (less than approximately

106 n states that effectively amounts to partial erasure of stored information.

107 ore propose that the previously demonstrated erasure of stored spatial memory and the disruption of p

108 upted ATX1 and CLF functions did not lead to erasure of the CLF- and ATX1-generated epigenetic marks,

109 Embryonic germ cells show erasure of the methylation markers (imprints) of the Igf

110 s thought to embody new learning rather than erasure of the original fear memory, although it is unkn

111 mic reorganization demonstrate that complete erasure of the polycomb repressive mark H3K27me3 is not

112 Here, we show that dynamic generation and erasure of the repressive histone modification tri-methy

113 imately 2-3 times this interval, a near full erasure of the synaptic connectivity pattern.

114 ts to a direct link between eviction-coupled erasure of the ubiquitin mark from ubH2B and co-transcri

115 As a consequence of both incomplete erasure of tissue-specific methylation and aberrant de n

116 3, one of the m(6)A methylases, led to m(6)A erasure on select target genes, prolonged Nanog expressi

117 on of new memories rather than in the simple erasure or forgetting of memories from acquisition.

118 with information theory through information erasure principle.

119 PGC-like state of genomic-imprint and DPPA3 erasure, recurrent hypermethylation of cancer-associated

120 including imprinted genes, epimutations, and erasure-resistant loci, which may be involved in transge

121 g no heat are separated from heat-generating erasure steps which are logically irreversible but therm

122 ), we randomly assigned 738 patients (in the ERASURE study) and 1306 patients (in the FIXTURE study)

123 dose than with placebo or etanercept: in the ERASURE study, the rates were 65.3% with 300 mg of secuk

124 dose than with placebo or etanercept: in the ERASURE study, the rates were 81.6% with 300 mg of secuk

125 he most direct test of a storage role is the erasure test.

126 ctures, are more stable against thermal self-erasure than conventional memory devices.

127 processes of memory consolidation and memory erasure that occur during sleep.

128 otential for TE activation during global 5mC erasure, thereby acting as a failsafe to ensure TE suppr

129 rsion process provides the necessary quantum erasure to eliminate which-path information in the photo

130 Although the beginning of methylation erasure was evident on the H19 paternal allele at 9.5 dp

131 served global 5-hydroxymethylcytosine (5hmC) erasure within three days of culture initiation.