ライフサイエンスコーパス: error-free

1 oderate exercise in humans is isocapnic, or 'error-free'.

2 ly 18% for short reads of 100 bases that are error free).

3 esponding Cq if and only if E is taken to be error free.

4 TLS parameters; almost all residual TLS were error-free.

5 e remaining mitotic divisions appeared to be error-free.

6 Replication in E. coli was essentially error-free.

7 ction of lesion bypass and that it is mostly error-free.

8 by homologous recombination, which is mostly error-free.

9 G3 C8-IQ adducts, incorporation was largely error-free.

10 This pathway is error-free.

11 .e., can be error-prone), but it can also be error-free.

12 ro, has led to the description of pol-eta as error-free.

13 the approach and extension steps are largely error-free.

14 with recombinational repair must be largely error-free.

15 itude in their preferences for mutagenic vs. error-free 8-oxoG lesion bypass.

16 s opposite a variety of lesions in both near error-free and error-prone bypass.

17 hat Polkappa plays an important role in both error-free and error-prone lesion bypass in humans.

18 ae, Rad6 and Rad18 are required for both the error-free and error-prone lesion bypass mechanisms.

19 e RAD6 epistasis group that function in both error-free and error-prone repair.

20 locus AID-initiated lesions are processed by error-free and error-prone repair.

21 th pol eta than with pol kappa and that both error-free and error-prone syntheses are observed with t

22 probe the cellular mechanism underlying the error-free and error-prone translesion DNA syntheses, in

23 cated that human Polkappa is capable of both error-free and error-prone translesion DNA synthesis in

24 ay of psoralen cross-link repair in yeast is error-free and involves the formation of DSB intermediat

25 pol eta might potentially contribute to both error-free and mutagenic bypass of gamma-HOPdG.

26 njugating and DNA-binding activities, in the error-free and mutagenic modes of damage bypass.

27 d by transcriptional bypass, generating both error-free and mutant transcripts with AMP misincorporat

28 refore highly robust, and produces virtually error-free arrays.

29 n a 24.48-fold increase in the percentage of error-free assembled fragments (from 3.23% to 79.07%).

30 ty ranging from 131-250 targets, we observed error-free assemblies for 90.5% of all targets.

31 act, most of the times, Slicembler generates error-free assemblies.

32 dicts the narrow temperature window in which error-free assembly can occur.

33 units to ensure free energy minimization and error-free assembly.

34 sonic waves to allow for the effective and "error free" assembly wherein an entangled net of fibers

35 With the G1 N 2-IQ adduct, the product was error-free at the site opposite the base and then stalle

36 sylase (UNG), an enzyme normally involved in error-free base excision repair.

37 cess, but the resulting uracils are repaired error-free because error-prone repair does not gain acce

38 spindles suggests that Pkl1p contributes to error-free biorientation by promoting normal spindle pol

39 CTG expansions in conjunction with the error-free branch of postreplication repair (PRR).

40 Owing to the genetic flexibility and error-free bulk production, bio-nanostructures such as f

41 the anti-conformation in human pol gamma for error free bypass of 8-oxo-dG and substitution to Cys al

42 size can be a major factor for efficient and error-free bypass at these adducts by TLS DNA polymerase

43 , PolDIP2 stimulates both the efficiency and error-free bypass of 8-oxo-7,8-dihydrodeoxyguanosine (8-

44 processivity and catalytic efficiency of the error-free bypass of a 8-oxo-G lesion by both Pols eta a

45 is a polymerase enzyme, specialized for near error-free bypass of certain bulky chemical lesions to D

46 d here reveal a role for yeast Poleta in the error-free bypass of cyclobutane dimers and (6-4) photop

47 t poliota might therefore participate in the error-free bypass of DE-adducted dA in vivo by predomina

48 Our results highlight a novel mechanism for error-free bypass of deoxyuridines generated within ssDN

49 Replication repair mediates error-free bypass of DNA damage in a series of steps tha

50 This promotes error-free bypass of DNA damage lesions.

51 wo downstream E3 ligases needed to carry out error-free bypass of DNA lesions.

52 nthesis DNA polymerase additionally promotes error-free bypass of GO lesions.

53 merases kappa and iota are necessary for the error-free bypass of N(2)-CEdG and N(2)-CMdG.

54 reover, during RNA extension Poleta performs error-free bypass of the 8-oxoguanine and thymine dimer

55 unts for the dA adduct blockage and the near-error-free bypass of the dG lesion.

56 the other daughter strand, and the result is error-free bypass of the lesion.

57 DNA polymerase eta (Poleta) functions in error-free bypass of ultraviolet light-induced DNA lesio

58 to conflict with the role of Pol eta in the error-free bypass of UV lesions.

59 NA polymerase eta (Pol eta) functions in the error-free bypass of UV-induced DNA lesions, and a defec

60 te, but one that yields mutations instead of error-free bypass.

61 a Lys-63-linked polyubiquitin chain promotes error-free bypass.

62 whereas pol eta is involved primarily in its error-free bypass.

63 rporate a C provides a unique means for the "error-free" bypass of this noninstructional lesion.

64 Physicians provided error-free care in 73% of the uncomplicated encounters,

65 Error-free cell division depends on the assembly of the

66 inate the spatiotemporal dynamics needed for error-free cell division.

67 Continuous and error-free chromosome inheritance through the cell cycle

68 Error-free chromosome segregation requires stable attach

69 lly demonstrate the possibility of achieving error-free clocked non-volatile spin wave logic device,

70 We conclude that the error-free component of the RAD6/RAD18 pathway completes

71 ately 60-70% of these events depended on the error-free component of the RAD6/RAD18 pathway, with the

72 Error-free, conservative HR involves strand invasion and

73 were assembled in one reaction, we observed error-free constructs for 70.6%.

74 and molecular topologies (treated herein as error-free) contain contradictory groupings across analy

75 h both error-prone translesion synthesis and error-free damage avoidance can be detected and quantifi

76 s event determines whether an error-prone or error-free damage avoidance pathway is taken.

77 s to putative tumor suppressors and controls error-free damage bypass by an unknown mechanism.

78 polyubiquitin chains, previously involved in error-free damage tolerance.

79 Physical map assembly from error free data is straightforward and can be accomplish

80 the VAF factorization problem in the case of error-free data and extend this solution to real data wi

81 he method is useful for obtaining systematic error-free data from (13)C tracer experiments and can al

82 d writing but do not offer random-access and error-free data recovery from low-cost, portable devices

83 (instead of easier, as one would expect with error-free data), and as a consequence the quality of th

84 s not appear to regulate other DDT pathways, error-free DDT mechanisms are employed by H2Bub1-deficie

85 steady state levels of APE1 and consequently error free DNA repair.

86 nation (HR) by the RAD51 recombinase enables error-free DNA break repair.

87 Error-free DNA can subsequently be isolated using one of

88 Evidence for an error-free DNA damage tolerance process in eukaryotes (a

89 CNA, pinpointing ZRANB3 as a key effector of error-free DNA damage tolerance.

90 nabling homologous recombination (HR)-based, error-free DNA double-strand break repair (DSBR) and int

91 can be attributed to an optimal induction of error-free DNA repair in a DR region of minimal mutabili

92 PH1 functions to channel DNA lesions into an error-free DNA repair pathway.

93 Error-free DNA synthesis involves 8-oxoG adopting an ant

94 ICLs in a reaction that involves extensive, error-free DNA synthesis.

95 hia coli and constitute the major pathway of error-free DSB repair.

96 nt mechanistic insights into C-NHEJ-mediated error-free DSBR of the transcribed genome.

97 storing the missing sequences, thus allowing error-free DSBR.

98 nation represents an important means for the error-free elimination of DNA double-strand breaks and o

99 At low DNA/protein ratios, an error-free end-joining mechanism predominated over MHEJ.

100 Efficient, error-free, end joining observed in such in vitro reacti

101 ells, TLS during replication can be markedly error-free even opposite a highly distorting DNA lesion.

102 er Peri:O(6)-BnG base pair, and in contrast, error-free extension was observed for the smaller BIM:O(

103 the TLS machinery to function in a much more error-free fashion than could have been predicted from t

104 a is capable of bypassing 8-oxoG in a mostly error-free fashion, thus preventing GC-->AT transversion

105 bypass and that it occurs in a predominantly error-free fashion.

106 n to bypass cyclobutane-type TT dimers in an error-free fashion.

107 nd pol eta, which bypasses DNA lesions in an error-free fashion.

108 his lesion in human cells occurs in a highly error-free fashion.

109 have similar accuracies predicting genes on error-free fragments, in the presence of sequencing erro

110 t the expense of a reduction in the level of error-free gene conversion.

111 the main determinant of stable heredity and error-free gene expression.

112 rvation of protein function and to guarantee error-free genome annotations, in general: sets with mil

113 Error-free genome duplication and segregation are ensure

114 T, are highly suitable for rapid recovery of error-free haplotypes obtained by 454-sequencing of ampl

115 sting of Shu1, Shu2, Csm2 and Psy3, promotes error-free homologous recombination (HR) by an unknown m

116 iminished proficiency for DNA repair via the error-free homologous recombination (HR) repair pathway.

117 ngle-stranded DNA facilitates DSB repair via error-free homologous recombination (HR) while stymieing

118 To repair DSBs, error-free homologous recombination (HR), and/or error-p

119 r prone non-homologous end-joining (NHEJ) or error-free homologous recombination.

120 B repair from error-prone DNA end-joining to error-free homologous recombination.

121 contribute to genomic stability by promoting error-free HRR.

122 rate at which information can be transmitted error-free in fibre-optic communication systems?

123 ed translesion synthesis past this adduct is error-free in the context of semiconservative replicatio

124 site, disrupting interactions necessary for error-free incorporation of dC opposite the lesion.

125 MD simulations show that the near error-free incorporation of dCTP opposite the major benz

126 ly been interpreted as the ultimate limit of error-free information transmission rate.

127 Together, these results suggest that the error-free insertion of dAMP opposite the 3'-T of the ci

128 " the repair process in favor of potentially error-free interchromatid homologous recombination at th

129 Error-free lesion bypass and error-prone lesion bypass a

130 s to the Rad18-SHPRH complexes necessary for error-free lesion bypass in cells.

131 quitin binding site of Mms2 is necessary for error-free lesion bypass in the RAD6 pathway and provide

132 are required for chain assembly in vitro and error-free lesion bypass in vivo.

133 been postulated to be an intermediate in an error-free lesion bypass pathway.

134 However, strains without error-free lesion bypass proteins Ubc13, Mms2 and Mph1 d

135 irst direct evidence for the existence of an error-free lesion replication mechanism and also demonst

136 egulation of CD4 expression is essential for error-free lineage choice during major histocompatibilit

137 cific positive selection and is critical for error-free lineage choice in TCR-transgenic mice whose t

138 ns-anti-benzo[a]pyrene-N:(2)-dG lesion in an error-free manner by incorporating a C opposite the bulk

139 and such rNMPs are efficiently removed in an error-free manner by ribonuclease (RNase) H2.

140 model ICLs were repaired mostly (>94%) in an error-free manner in both hosts.

141 osite this lesion replicates DNA in a highly error-free manner in human cells.

142 is past C or (m)C in a CPD also occurs in an error-free manner is for an (m)C in the 5'-position of a

143 the a priori expectation that HRR acts in an error-free manner to repress three classes of genetic al

144 owever, this bypass was achieved in a mainly error-free manner with AA incorporation opposite the TT

145 ta synthesize past the 3'-(m)C CPD in a >99% error-free manner, consistent with the highly water-expo

146 ay of DNA lesions and act in a predominantly error-free manner, implicates a crucial role for Rev1 in

147 or U in a CPD by pol eta occurs in a highly error-free manner, the only in vitro evidence that synth

148 pposite the phenanthriplatin-dG adduct in an error-free manner, with specificity for CTP incorporatio

149 cellular bypass of the lesion occurred in an error-free manner.

150 ndently of these Pols and in a predominantly error-free manner.

151 tes to lesion bypass in a mutagenic or in an error-free manner.

152 duced photoproducts from DNA in a relatively error-free manner.

153 y is essential for the removal of ICLs in an error-free manner.

154 ymine dimers efficiently and in a relatively error-free manner.

155 nslesion synthesis across gamma-OH-PdG in an error-free manner.

156 rt, a process that bypasses DNA damage in an error-free manner.

157 a donor may be required to repair ICLs in an error-free manner.

158 Homologous recombination is an error-free mechanism for the repair of DNA double-strand

159 pass of epsilonA proceeded principally by an error-free mechanism in which the undamaged strand was u

160 be repaired by homologous recombination, an error-free mechanism, or by non-homologous end joining,

161 ated by both an error-prone mechanism and an error-free mechanism.

162 eplication can be bypassed by error-prone or error-free mechanisms.

163 ection is achieved in prometaphase to ensure error-free mitosis remains unknown.

164 dRrp6 is required for cell proliferation and error-free mitosis, but the core exosome subunit Rrp40 i

165 of microtubule dynamics is essential for an error-free mitosis.

166 appears to be exerted by the RAD5-dependent error-free mode of bypass DNA repair.

167 itination of PCNA by yRad5 (E3) promotes the error-free mode of bypass.

168 report suggested that MacDinB-1 works in an error-free mode to repair cyclobutane pyrimidine dimers.

169 have revealed the previously underestimated error-free nature of NHEJ and provided new tools to furt

170 s have shown that poliota is also capable of error-free nucleotide incorporation opposite the bulky m

171 Generally, error-free nucleotide insertion opposite the lesions ten

172 ltage (0.5 VPP) and efficient 0.9 fJ per bit error-free operation.

173 er chromatid recombination (SCR), generating error-free or error-prone homologous recombination (HR)

174 tions of TAM are not affected by the loss of error-free or error-prone lesion bypass pathways, they a

175 Cells employ error-free or error-prone postreplication repair (PRR) p

176 cesses to tolerate genomic lesions by either error-free or error-prone repair.

177 iting higher susceptibility to UNG-triggered error-free or error-prone resolution.

178 tides opposite DNA damage sites resulting in error-free or mutagenic damage bypass.

179 ssed by DNA topoisomerase 1 (Top1) by either error-free or mutagenic repair.

180 NHEJ may either be error-free or mutagenic with deletions or insertions at

181 Homologous recombination (HR), the error-free pathway for double-strand break (DSB) repair,

182 romatid recombination (SCR) is a potentially error-free pathway for the repair of DNA lesions associa

183 antly via translesion synthesis, whereas the error-free pathway functions as a backup system.

184 and context; cells preferentially employ the error-free pathway in S phase and do not require MEC1-de

185 n of double strand DNA breaks proceeds in an error-free pathway of homologous recombination (HR), whi

186 A third error-free pathway relies on the presence of Mms2, but m

187 nt mutagenesis by inhibiting an alternative, error-free pathway that depends on homologous recombinat

188 rases, polyubiquitylation is required for an error-free pathway that probably involves a template swi

189 n synthesis, polyubiquitination activates an error-free pathway, elusive in mammals, enabling damage

190 ars to mediate AFB1-induced mutagenesis when error-free pathways are compromised.

191 directly replicate over the lesion, whereas error-free pathways use an undamaged duplex as a templat

192 ficiency, all groups also had to demonstrate error-free performance.

193 This challenges the popular notion that error-free phonological retrieval requires guidance from

194 d ligand shell for kinetically competent and error-free photo-assembly of the Mn4CaO5-cluster.

195 usually necessary but not sufficient for an error-free plan of care.

196 ucts of the UBC13 and MMS2 genes function in error-free post-replicative DNA repair in the yeast Sacc

197 activity of proteasomes is not required for error-free post-replicative repair.

198 mechanisms are homologous recombination and error-free postreplication repair (EF-PRR).

199 First, we show that genes in the error-free postreplication repair (PRR) pathway prevent

200 e channeled into recombination-dependent and error-free postreplication repair.

201 proteins dictates the repair of DSBs by the error-free process of homologous recombination (HR).

202 us recombination (HR) pathway, a potentially error-free process that utilizes a homologous sequence a

203 ovides explicit expressions for (1) yield of error-free protein, (2) fraction of prematurely terminat

204 cts in either the error-prone (rev1Delta) or error-free (rad30Delta) branches of PRR, but did not enh

205 not assume a linear relationship between the error-free read and shadow counts and provides more accu

206 In contrast, fast and efficient error-free reading places more consistent demands on bot

207 e nanopore sequencers, while still producing error-free readouts with the highest reported informatio

208 embly can be performed by k-mer extension in error-free reads, this algorithm is unsuccessful with th

209 ers, especially when comparing the number of error-free reads.

210 se zeta/Rev1 and DNA polymerase eta, and the error-free, recombination-dependent component of this pa

211 -links can be repaired by three pathways: an error-free recombinational pathway requiring NER and HR

212 alse alleles depend upon the availability of error-free reference genotypes or reliable pedigree data

213 hemical evidence to show that BRCA1 promotes error-free rejoining of DSBs in human breast carcinoma c

214 e-dependent inhibitor of cNHEJ that promotes error-free repair by homologous recombination during cel

215 mutant cells to PARP inhibition and restores error-free repair by HR.

216 C-induced DNA cross-links at the expense of error-free repair by sister chromatid recombination.

217 llegitimate second-end capture to ensure the error-free repair of a DNA double-strand break.

218 or enhance c-myc genomic instability, due to error-free repair of AID-initiated lesions, in Ag-stimul

219 it also serves as the primary mechanism for error-free repair of DNA double strand breaks.

220 Error-free repair of DNA double-strand breaks (DSBs) is

221 Fanconi anemia (FA) pathway, which promotes error-free repair of DNA double-strand breaks, is requir

222 merase II (Top2) cleavage complexes to allow error-free repair of DNA double-strand breaks, thereby c

223 These results reveal a role for HMGB1 in the error-free repair of DNA lesions.

224 BRCA2 tumour suppressor is essential for the error-free repair of double-strand breaks (DSBs) in DNA

225 process of homologous recombination promotes error-free repair of double-strand breaks and is essenti

226 The error-free repair of double-stranded DNA breaks by homol

227 notype indicates that they are important for error-free repair of spontaneous and induced DNA lesions

228 moval of UVC-induced lesions and facilitated error-free repair of TFO-ICLs in mouse fibroblasts.

229 divert cells towards error-prone instead of error-free repair pathways, dramatically increasing the

230 ologous recombination, which is typically an error-free repair process.

231 f the DSB ends if they are compatible (i.e., error-free repair) or sequence alteration upon rejoining

232 Tdp1 and the 3'-phosphate by Tpp1 to mediate error-free repair.

233 1 filament assembly and stability, promoting error-free repair.

234 human DNA polymerase-iota (Poliota) promotes error-free replication across 1-MeA.

235 polymerases, whereby pol II is necessary for error-free replication and pol V for error-prone replica

236 gh hydrogen bonding is clearly important for error-free replication by this Y-class DNA polymerase, o

237 Human HLTF, implicated in error-free replication of damaged DNA and tumour suppres

238 NA polymerase (Pol) eta, which catalyzes the error-free replication of template thymine-thymine (TT)

239 ve site, and offer a basis for understanding error-free replication of the BP-derived stereoisomeric

240 umans, DNA polymerase (Pol) eta functions in error-free replication of ultraviolet-damaged DNA, and P

241 DNA polymerase eta (Poleta) functions in error-free replication of UV-damaged DNA, and in vitro i

242 NA polymerase eta (hPoleta) functions in the error-free replication of UV-damaged DNA, and mutations

243 DNA polymerase (Pol) (eta) functions in the error-free replication of UV-damaged DNA, and Pol(eta) h

244 haromyces cerevisiae RAD30 gene functions in error-free replication of UV-damaged DNA.

245 quirement of yeast Polzeta for predominantly error-free replication past thymine glycol (Tg), a DNA l

246 ols), whereas Poleta promotes proficient and error-free replication through CPDs.

247 endent postreplication repair (PRR) in which error-free replication through the DNA lesion occurs by

248 reviously, we have shown that proficient and error-free replication through the gamma-HOPdG (gamma-hy

249 and Pol zeta function together in promoting error-free replication through the lesion, and based on

250 ic polymerases in its proficient ability for error-free replication through ultraviolet-induced cyclo

251 stages, respectively, are representative of error-free replication, with MeFapy-dG in the anti confo

252 ucts, which gives insights how Rev1 achieves error-free replication.

253 n and, while replication across alpha-dA was error-free, replicative bypass of alpha-dC and alpha-dG

254 The frequent k-mers constitute a reduced but error-free representation of the experiment, which can i

255 ant, or Rad30) plays an important role in an error-free response to unrepaired UV damage during repli

256 s, but constraints may emerge when immediate error-free responses are required and evolutionary or de

257 ing a published phylogenetic estimate is not error-free, retaining a full record of the provenance of

258 ould allow renewed attempt for repair by the error-free RNase H2-dependent pathway in vivo.

259 n of Pols kappa and zeta implicates a highly error-free role of Poleta in TLS opposite CPDs in mammal

260 ethidium bromide, as tools to facilitate the error-free self-assembly of DNA nanostructures.

261 to our language processing mechanisms is an error-free sequence of words.

262 family, where Multipass generates 20 % more error-free sequences than current state of the art metho

263 allow generation of a set of high confidence error-free sequences.

264 that significantly improves the fraction of error-free sequences.

265 cations of this process under assumptions of error-free sequencing and perfect mapping, using cytosin

266 sis by pol eta is likely to be predominantly error-free, since the probability of correct insertion a

267 e stability as it promotes repair of DSBs by error-free sister-chromatid recombination (SCR), thereby

268 magnification and quality, and analysis with error-free software, the VLA can be measured precisely a

269 The error-free structured PEC area was found to be significa

270 n elegant means for promoting proficient and error-free synthesis through N2-adducted guanines that o

271 Poliota and Polkappa promotes efficient and error-free synthesis through the HNE-dG adducts, in whic

272 ng correct dCMP opposite alpha-OH-PdG during error-free synthesis.

273 g is a week-long process that produces 5,188 error-free synthetic DNAs in a single run of NGS with a

274 ped TBIO method of PCR-based gene synthesis, error-free synthetic genes for the human protein kinases

275 show that the yeast Rad5 protein can promote error-free template switching and replication past a DNA

276 trand DNA synthesis and subsequent bypass by error-free template switching.

277 or-prone translesion synthesis (TLS), and an error-free, template-switching pathway in Saccharomyces

278 e-derived adenine lesion (dA*); while mainly error-free, the identity of misincorporated bases is inf

279 on and orientation of the hairs is virtually error free, thus forming a nearly perfect parallel array

280 ic TLS in yeast, Rev1 promotes predominantly error-free TLS opposite UV lesions in humans.

281 kappa and zeta function together and mediate error-free TLS, whereas in the other, poltheta functions

282 Whereas TS is mainly error-free, TLS can work in an error-prone manner and, a

283 om high-fidelity replicative DNA processing (error-free) to low-fidelity translesion DNA synthesis (e

284 When error-free tolerance is disrupted through deletion of MM

285 In the presence or absence of Mms2-dependent error-free tolerance, the catalytic dead strain of Rev1

286 sequent sequencing of the mCherry cDNA shows error-free transcription.

287 d frequency regulation of Msn2 is limited to error-free transduction of signal identity, but not sign

288 In particular, the distance score allowed error-free transfer of enzyme function for the 10% most

289 greater latitude in promoting efficient and error-free translesion DNA synthesis through the diverse

290 To better understand the role of Poleta in error-free translesion DNA synthesis, here we examine th

291 ow that H2Bub1 normally functions to promote error-free translesion synthesis (TLS) mediated by DNA p

292 mutagenic translesion synthesis by Polzeta, error-free translesion synthesis by Poleta, and postrepl

293 indicate that polymerase eta is involved in error-free translesion synthesis past some cisplatin add

294 xcision repair is generally considered to be error free, translesion synthesis can result in mutation

295 We also demonstrate simultaneous error-free transmission of two signals at different carr

296 nd the proportion of visits that resulted in error-free treatment plans.

297 Because data are rarely error free, we recommend that researchers use methods, s

298 tion, these approaches hindered designing an error free WGSA pipeline.

299 and retain only those DNA molecules that are error free with respect to the target.

300 upstream of the abasic lesion is replicated error-free; yet dramatically, once Dpo4 encounters the l