ライフサイエンスコーパス: erythropoiesis

1 ruction of erythroblasts causing ineffective erythropoiesis.

2 of key erythroid genes and modulated ex vivo erythropoiesis.

3 inflammatory cues, and iron requirements for erythropoiesis.

4 f erythroblast enucleation during definitive erythropoiesis.

5 and trafficking of the CD47 isoforms during erythropoiesis.

6 ovel strategies for augmenting or inhibiting erythropoiesis.

7 s erythroid lineage competence and effective erythropoiesis.

8 d regulator that inhibits hepcidin in stress erythropoiesis.

9 on toward megakaryopoiesis at the expense of erythropoiesis.

10 s several species, and active in stimulating erythropoiesis.

11 cts of Ex12 signaling on megakaryopoiesis or erythropoiesis.

12 estigate the role of renal epithelial HIF in erythropoiesis.

13 rdinated expression of these proteins during erythropoiesis.

14 el hematopoietic function of VEGF-C in fetal erythropoiesis.

15 uclear opening formation throughout terminal erythropoiesis.

16 signals that are distinct from steady-state erythropoiesis.

17 of GATA1s promoted megakaryopoiesis, but not erythropoiesis.

18 d demonstrating that RBPMS is a regulator of erythropoiesis.

19 an important involvement of PIAS proteins in erythropoiesis.

20 identify new genes and alleles that regulate erythropoiesis.

21 One component of this response is increased erythropoiesis.

22 y as a powerful quality control mechanism in erythropoiesis.

23 order characterized by a selective defect in erythropoiesis.

24 ng heme and translation in the regulation of erythropoiesis.

25 e more incisive study of normal and aberrant erythropoiesis.

26 tatus and based on health outcomes, not just erythropoiesis.

27 a direct effect of inflammatory cytokines on erythropoiesis.

28 functional connections between genes during erythropoiesis.

29 ts into the context-specific role of TAL1 in erythropoiesis.

30 klf, and EpoR, which are required for proper erythropoiesis.

31 poietin-a glycoprotein hormone that controls erythropoiesis.

32 mediates hepcidin suppression during stress erythropoiesis.

33 ed in a striking loss of primitive embryonic erythropoiesis.

34 mice did not rescue impaired HPC function or erythropoiesis.

35 ibility, we evaluated the impact of DZNep on erythropoiesis.

36 anemia, including that caused by ineffective erythropoiesis.

37 enhanced supply of iron to support expanded erythropoiesis.

38 xamples of variation between human and mouse erythropoiesis.

39 ential for gender specific EPO action beyond erythropoiesis.

40 in improving our understanding of mammalian erythropoiesis.

41 findings demonstrate a key role for BDH2 in erythropoiesis.

42 tin-mediated JAK2 signaling is essential for erythropoiesis.

43 any roles of lncRNAs in normal and perturbed erythropoiesis.

44 riptional regulatory hierarchy that controls erythropoiesis.

45 lization by red blood cell precursors during erythropoiesis.

46 gakaryocyte lineage but downregulated during erythropoiesis.

47 lting in enhanced self-renewal and increased erythropoiesis.

48 rentiation, inhibition of EZH2 may influence erythropoiesis.

49 Gata1 and Tal1 and is essential for terminal erythropoiesis.

50 hange in a specific COPII cargo critical for erythropoiesis.

51 l regulatory dynamics during murine terminal erythropoiesis.

52 hting a key function for this protein during erythropoiesis.

53 GATA1 is a critical regulator of erythropoiesis.

54 eriods and fail to respond to TH by enhanced erythropoiesis.

55 the initial activation of the Gata1 gene and erythropoiesis.

56 n prolonged relative to that of actin during erythropoiesis.

57 ellular stores and subsequent stimulation of erythropoiesis.

58 c syndromes are characterised by ineffective erythropoiesis.

59 ESAs have effects beyond erythropoiesis.

60 iron atoms every second to maintain adequate erythropoiesis.

61 cidin expression to supply adequate iron for erythropoiesis.

62 in the development of anemia and ineffective erythropoiesis.

63 cidin augments iron delivery for intensified erythropoiesis.

64 th other tissues but ultimately is unique to erythropoiesis.

65 nes critical to cellular processes including erythropoiesis.

66 uggest the involvement of new genes in human erythropoiesis.

67 e splicing program occurring during terminal erythropoiesis.

68 genic growth factor, in the transition to FL erythropoiesis.

69 the role of long noncoding RNAs (lncRNAs) in erythropoiesis.1 This is an initial step forward in our

70 ntial for erythrocyte regeneration in stress erythropoiesis, a vital process in pathologies, includin

71 growth in vitro is associated with elevated erythropoiesis, an obligate step towards erythroid recov

72 in mice results in a significant increase in erythropoiesis and a decrease in the hematopoietic stem

73 To study erythropoiesis and anemia, one must have a firm foundati

74 such factors and their emerging roles during erythropoiesis and anemia.

75 d by interleukin 6, leads to iron-restricted erythropoiesis and anemia.

76 on repressed Gata2 transcription and induced erythropoiesis and apoptosis of HSPCs.

77 Furthermore, there was a disruption in erythropoiesis and B-cell differentiation.

78 there is a need to better understand stress erythropoiesis and changes in iron metabolism during pre

79 rovides a genetic tool for further exploring erythropoiesis and congenital anemias.

80 eukemogenic CM fusion protein disrupts adult erythropoiesis and creates stress-resistant preleukemic

81 phyrin metabolites, resulting in ineffective erythropoiesis and devastating skin photosensitivity.

82 used beta-thalassemia, minihepcidin improves erythropoiesis and does not alter the beneficial effect

83 ficiency in mice caused failure of primitive erythropoiesis and embryonic death.

84 depletion phenotypes in zebrafish primitive erythropoiesis and granulocytic differentiation in cultu

85 portant roles of H2AX in late-stage terminal erythropoiesis and hematopoietic stem cell function.

86 rate hematopoietic tissues, is essential for erythropoiesis and heme synthesis in vivo and in culture

87 free alpha-globin chains causing ineffective erythropoiesis and hemolysis.

88 ing candidate for the link between increased erythropoiesis and hepcidin suppression.

89 on the brain, stem cells, and the process of erythropoiesis and identifies gaps in our knowledge of w

90 of ASXL1 in cord blood CD34(+) cells reduced erythropoiesis and impaired erythrocyte enucleation.

91 pairs hypoxemia compensations by restricting erythropoiesis and increases the risk of ischemic stroke

92 Our study unveils a key role for ASXL1 in erythropoiesis and indicates that ASXL1 loss hinders ery

93 s offer insight into the mechanism of stress erythropoiesis and into disorders of erythrocyte generat

94 Erythropoiesis and iron deficiency suppress hepcidin via

95 ersible epigenetic modifications during both erythropoiesis and iron deficiency.

96 eted factors that exert a negative effect on erythropoiesis and iron use.

97 on conditions that might promote ineffective erythropoiesis and iron-loading anemia.

98 protein hormone that is essential for normal erythropoiesis and is predominantly synthesized by perit

99 The adult kidney plays a central role in erythropoiesis and is the main source of erythropoietin

100 l for human studies of normal and disordered erythropoiesis and its effect on iron homeostasis.

101 how hypoxia regulates iron levels to support erythropoiesis and maintain systemic iron homeostasis.

102 ta show that NR4A1 expression by MPPS limits erythropoiesis and megakaryopoeisis, permitting developm

103 iPSC clones demonstrated profound defects in erythropoiesis and megakaryopoiesis and deregulated expr

104 xpression at two distinct critical stages of erythropoiesis and megakaryopoiesis.

105 not HbE) trait was associated with increased erythropoiesis and mildly suppressed hepcidin, suggestin

106 at synergistically facilitates apoptosis and erythropoiesis and restrains adverse proliferation, indi

107 growth factor-beta superfamily in late-stage erythropoiesis and reveal potential of a modified ActRII

108 okines, as well as transitory suppression of erythropoiesis and shortened red blood cell lifespan, al

109 efficiency is dynamically controlled during erythropoiesis and that enrich for target sites of RNA-b

110 hat Trim58 expression is induced during late erythropoiesis and that its depletion by small hairpin R

111 in ribosomal components but the link between erythropoiesis and the ribosome remains to be fully defi

112 Its roles in the maintenance of bone marrow erythropoiesis and thrombopoiesis have not been defined.

113 a master transcriptional repressor of adult erythropoiesis and thrombopoiesis.

114 t drl.3 plays an essential role in primitive erythropoiesis and, to a lesser extent, myelopoiesis tha

115 enomegaly, microcytic anemia, extramedullary erythropoiesis, and increased hemophagocytic macrophages

116 the underlying chain imbalance, ineffective erythropoiesis, and iron dysregulation, with several age

117 processes of hematopoiesis, granulopoiesis, erythropoiesis, and lymphopoiesis.

118 ed liver, serum iron, and ferritin), reduced erythropoiesis, and significantly decreased transferrin

119 mia signature indicated deregulation of host erythropoiesis, and the lung inflammation signature was

120 ssemia, minihepcidin ameliorates ineffective erythropoiesis, anemia, and iron overload.

121 ss by regulating transcriptional programs in erythropoiesis, angiogenesis and metabolism.

122 ntrol oxygen supply to tissues by regulating erythropoiesis, angiogenesis and vascular homeostasis.

123 r mechanisms by which iron and heme regulate erythropoiesis are not completely understood.

124 mechanisms of chromatin condensation during erythropoiesis are unclear.

125 ion of Erfe slightly ameliorated ineffective erythropoiesis, as indicated by reduced spleen index, re

126 fibroblast-like cells are critical for adult erythropoiesis, as they are the main source of erythropo

127 ssion of major transcriptional regulators of erythropoiesis, as well as major erythroid-important pro

128 partially compensated by avid extramedullary erythropoiesis at all erythroid stages in the spleen the

129 f hemochromatosis and induce iron-restricted erythropoiesis at higher doses.

130 lidomide acted early by transiently delaying erythropoiesis at the burst-forming unit-erythroid/colon

131 , AKAP10, regulates heme biosynthesis during erythropoiesis at the outer mitochondrial membrane.

132 terial burdens, implying that extramedullary erythropoiesis benefits the host.

133 iologically in iron deficiency and increased erythropoiesis but is pathologic in thalassemia and hemo

134 .sTfR may be useful to assess iron-deficient erythropoiesis, but inflammation influences its interpre

135 We found that the development of HPCs and erythropoiesis, but not HSC function, was rescued by red

136 teract to regulate chromatin architecture in erythropoiesis, but the mechanistic basis for this regul

137 udy, we have demonstrated that LPA activates erythropoiesis by activating the LPA 3 receptor subtype

138 and integrated stress response (ISR) during erythropoiesis by heme-regulated eIF2alpha kinase (HRI).

139 hat coordinates heme and globin synthesis in erythropoiesis by inhibiting protein synthesis of globin

140 -binding protein Elavl1a regulates embryonic erythropoiesis by maintaining appropriate levels of gata

141 Thus, Rcor1 promotes erythropoiesis by repressing HSC and/or progenitor genes

142 the erythroid transcriptome and how studying erythropoiesis can yield genomic principles.

143 nisms have been proposed, the means by which erythropoiesis causes hepcidin suppression have been unc

144 se genetic background led to defective fetal erythropoiesis, characterized by anemia and lack of enuc

145 e alpha/beta-globin chain ratio, ineffective erythropoiesis, chronic haemolytic anaemia, compensatory

146 rst-forming units when cultured under stress erythropoiesis conditions.

147 herited disorder characterized by defects in erythropoiesis, congenital abnormalities, and predisposi

148 (ActRIIA) ligand trap, improved ineffective erythropoiesis, corrected anemia and limited iron overlo

149 avascular hemolysis and increased endogenous erythropoiesis damage vascular endothelia.

150 , the estimated prevalence of iron-deficient erythropoiesis decreased by 4.4-14.6 and 0.3-9.5 percent

151 of gata1 messenger RNA partially rescues the erythropoiesis defect caused by Elavl1 knockdown.

152 emia suggests that regulation of hepcidin by erythropoiesis dominates regulation by iron.

153 tanding of the roles of Rho GTPases in early erythropoiesis, downstream of cytokine signaling, and in

154 n exhibit rapid RBC turnover, with increased erythropoiesis, dramatically shortened RBC lifespan, and

155 ic features, that is, those with exaggerated erythropoiesis due to augmented erythropoietin (EPO) sen

156 uption of Tmod3 leads to impaired definitive erythropoiesis due to reduced progenitors, impaired eryt

157 y increased RBC turnover and higher rates of erythropoiesis during infection.

158 cts, especially hemozoin (Hz), in suppressed erythropoiesis during malaria, but the mechanism(s) invo

159 anding splenic haematopoietic stem cells and erythropoiesis during pregnancy.

160 yb However, adtrp1 knockdown does not affect erythropoiesis during primitive hematopoiesis (no effect

161 nemia; however, the mechanisms that underlie erythropoiesis dysfunction in these animals are unclear.

162 at least a subset of its target genes during erythropoiesis (e.g. beta-globin, alpha-hemoglobin stabi

163 etter quality and efficiency of HbF-enriched erythropoiesis elevated hemoglobin using fewer reticuloc

164 X did not affect the early stage of terminal erythropoiesis, enucleation was decreased.

165 Besides promoting erythropoiesis, EPO is also known to modulate retinal va

166 In contrast, definitive erythropoiesis failed and the mice died by E16.5, with p

167 to allow effective erythropoiesis, show that erythropoiesis fails when heme is excessive, and emphasi

168 Here, we determined that erythropoiesis failure occurs in these animals at the CF

169 Having no apparent effect on primitive erythropoiesis, FLKO mice show significant enhancement o

170 owever, persistent increased and ineffective erythropoiesis, for example in thalassemia, results in s

171 or beta (TGF beta) superfamily inhibitors of erythropoiesis, giving rise to a promising new investiga

172 macrophages in enhancing baseline and stress erythropoiesis has been emphasized over several decades,

173 An effect of thyroid hormone (TH) on erythropoiesis has been known for more than a century bu

174 O), a glycoprotein hormone indispensable for erythropoiesis, has biological activities that extend to

175 at TSPO deficiency does not adversely affect erythropoiesis, heme biosynthesis, bioconversion of ALA

176 or cell lines to examine the role of TSPO in erythropoiesis, heme levels, PPIX biosynthesis, phototox

177 ct on transferrin saturation, iron-deficient erythropoiesis, hemoglobin concentration, or packed RBC

178 alphaP and mTORC1, to circumvent ineffective erythropoiesis, highlighting heme and translation in the

179 ganese, and zinc) support iron's function in erythropoiesis, how these nutrients interact remains, to

180 ed compartmental model of thrombopoiesis and erythropoiesis in a BM toxicity context, after internal

181 nemia, erythroid hyperplasia and ineffective erythropoiesis in a mouse model of myelodysplastic syndr

182 thropoietin (EPO) levels, and extramedullary erythropoiesis in a process independent of Salmonella pa

183 ice, acetate supplementation augments stress erythropoiesis in an ACSS2-dependent manner.

184 uction occurred in parallel to a decrease in erythropoiesis in BM in mice with progressive disease.

185 roid progenitor (EP) contribute to defective erythropoiesis in DBA.

186 l hemoglobin expression was inhibited during erythropoiesis in embryonic day 13.5 and embryonic day 1

187 o with increased commitment toward primitive erythropoiesis in Foxf1-deficient embryos, whereas FOXF1

188 pic expression of miR-27a or miR-24 promoted erythropoiesis in human primary CD34+ haematopoietic pro

189 or by an increase in bone marrow and splenic erythropoiesis in IL-3 KO mice, as evidenced by higher l

190 t only of definitive, but also of primitive, erythropoiesis in mammals.

191 al step toward chromatin condensation during erythropoiesis in mice.

192 tem cell frequency associated with increased erythropoiesis in peripheral blood and bone marrow in yo

193 EC9 in humans, are critical for induction of erythropoiesis in response to stress.

194 ggest that nutritional vitamin D may enhance erythropoiesis in settings of 25-hydroxy vitamin D (25(O

195 accompanied by an alleviation of ineffective erythropoiesis in Th3/(+) mice.

196 l in ameliorating the anemia and ineffective erythropoiesis in thalassemias.

197 Impaired erythropoiesis in the deletion 5q (del(5q)) subtype of m

198 Central nurse macrophages promote erythropoiesis in the erythroblastic island niche.

199 .5, with anemia due to defects in definitive erythropoiesis in the fetal liver.

200 S29 mutations failed to rescue the defective erythropoiesis in the rps29(-/-) mutant zebra fish DBA m

201 oietic stem-cell frequency, cellularity, and erythropoiesis in the spleen.

202 phage-associated pathway supporting terminal erythropoiesis in this expansion system.

203 mice despite the presence of extramedullary erythropoiesis in this tissue.

204 We found that efficient stress erythropoiesis in vivo requires E2F-2, and we also ident

205 esults demonstrate a new mode of controlling erythropoiesis in which multiple components of the exoso

206 many factors including shape that changes in erythropoiesis, in senescence and in diseases ranging fr

207 Erythropoiesis, in which committed progenitor cells gene

208 ate, generating cells at different stages of erythropoiesis, including terminally differentiated nucl

209 ls, indicates that these observations may be erythropoiesis-independent and that EPO exhibits immunos

210 ssion of gata1a was not sufficient to rescue erythropoiesis, indicating that the regulation of hemato

211 27a and -24 expression induces apoptosis and erythropoiesis, inhibits adverse growth and partly relie

212 , but multiple linear regression showed that erythropoiesis inversely correlated with hepcidin only i

213 Mammalian erythropoiesis involves chromatin condensation that is i

214 reviously unrecognized regulatory pathway of erythropoiesis involving suppressor control by the NO me

215 Macrocytic anemia with abnormal erythropoiesis is a common feature of megaloblastic anem

216 lator of iron homeostasis, is repressed when erythropoiesis is acutely stimulated by erythropoietin (

217 Erythropoiesis is an important response to certain types

218 Stress erythropoiesis is best characterized in the mouse, where

219 This stress-induced erythropoiesis is distinct from basal red blood cell gen

220 Transcription profiling demonstrates that erythropoiesis is mainly controlled by a small group of

221 Steady-state erythropoiesis is primarily homeostatic, producing new e

222 He concluded that erythropoiesis is regulated by a humoral factor rather t

223 d in neonatal Pgc-1(c) pups, indicating that erythropoiesis is severely compromised.

224 with previous suggestions that human stress erythropoiesis is similar to fetal erythropoiesis, we de

225 Hepcidin levels are suppressed when erythropoiesis is stimulated, for example following acut

226 ther FGF-23 is involved in the regulation of erythropoiesis is unknown.

227 Although EKLF's function during early erythropoiesis is well studied, its role during terminal

228 , culminating in enucleation during terminal erythropoiesis, is poorly understood.

229 y regulate diverse gene groups during normal erythropoiesis, misregulation of which could be responsi

230 astic syndromes (MDS), including ineffective erythropoiesis, morphologic dysplasia and BM hyper-cellu

231 e mechanisms responsible for the ineffective erythropoiesis observed in the condition, which is chara

232 ompletely reversed ID anemia and ineffective erythropoiesis of Hri(-/-) , eAA, and Atf4(-/-) mice by

233 The defective terminal erythropoiesis of lineage-negative bone marrow cells of

234 In summary, the influence of erythropoiesis on hepcidin suppression associates with p

235 definitive hematopoiesis, but not primitive erythropoiesis or vasculogenesis.

236 uction (a regenerative anemia or ineffective erythropoiesis) or increased destruction, and define par

237 type, there were no differences in hepcidin, erythropoiesis, or hemoglobin between severe or moderate

238 ine mutations in RPS29 can cause a defective erythropoiesis phenotype using a zebra fish model.

239 mal and phenylhydrazine (PHZ)-induced stress erythropoiesis, PPAR-alpha agonists facilitate recovery

240 At these times, stress erythropoiesis predominates.

241 As erythropoiesis proceeded, GATA-1 directly activated miR-

242 th a t(1/2) of 59 days, corresponding to the erythropoiesis rate in humans.

243 -Thalassemia is characterized by ineffective erythropoiesis, reduced production of erythrocytes, anem

244 ts with MDS or MDS/MPN, the role of ASXL1 in erythropoiesis remains unclear.

245 Erythropoiesis requires rapid and extensive hemoglobin p

246 ubiquitin-conjugating enzyme induced during erythropoiesis, results in anemia.

247 ncRNAs that are dynamically expressed during erythropoiesis, show epigenetic regulation, and are targ

248 nto how heme is regulated to allow effective erythropoiesis, show that erythropoiesis fails when heme

249 which several genes that form a part of the erythropoiesis signature are upregulated in both sJIA an

250 These erythropoiesis-specific regulatory relationships were no

251 were compared with estimated iron-deficient erythropoiesis (sTfR concentration >8.3 mg/L): 1) the ex

252 e the estimated prevalence of iron-deficient erythropoiesis.sTfR may be useful to assess iron-deficie

253 beling was applied for the first time to the erythropoiesis stimulating agent (ESA) products, which f

254 Addition of an erythropoiesis-stimulating agent could improve response

255 ems have provided strong stimuli to decrease erythropoiesis-stimulating agent use and increase intrav

256 Erythropoiesis-stimulating agents (ESAs) are commonly us

257 n supplementation alone and as an adjunct to erythropoiesis-stimulating agents (ESAs) compared with E

258 African Americans require higher doses of erythropoiesis-stimulating agents (ESAs) during dialysis

259 m (PPS) and changes to dosing guidelines for erythropoiesis-stimulating agents (ESAs) in 2011 appear

260 ed controlled trials assessing the effect of erythropoiesis-stimulating agents (ESAs) in critically i

261 odysplastic syndromes (MDS) are treated with erythropoiesis-stimulating agents (ESAs), with a respons

262 stores and use of intravenous (iv) iron and erythropoiesis-stimulating agents (ESAs).

263 gradually moved away from the liberal use of erythropoiesis-stimulating agents as the main treatment

264 d from myelodysplastic syndromes, relying on erythropoiesis-stimulating agents to cope with anemia, a

265 -and-see approach for asymptomatic patients, erythropoiesis-stimulating agents, androgens, or immunom

266 Trials raising concerns about erythropoiesis-stimulating agents, revisions to their la

267 Inherited anemias with ineffective erythropoiesis, such as beta-thalassemia, manifest inapp

268 reduction in B lymphopoiesis and compromised erythropoiesis, suggesting that hematopoietic lineage/pr

269 n the estimated prevalence of iron-deficient erythropoiesis than did the regression approach.

270 F1) is a master transcriptional regulator of erythropoiesis that is mutated in a subset of these anem

271 novel function is added to its known role in erythropoiesis, the kidney emerges as an important regul

272 ulating iron in blood plasma is destined for erythropoiesis, the mechanisms by which erythropoietic d

273 ominant mutation in ALAS2 can perturb normal erythropoiesis through cell-nonautonomous effects.

274 roxylase inhibitor that promotes coordinated erythropoiesis through HIF-mediated transcription.

275 d a time-course RNA-Seq dataset during human erythropoiesis to infer regulatory relationships specifi

276 s regulate self signaling, as is relevant to erythropoiesis, to clearance of rigid RBCs after blood s

277 semia and polycythemia vera (PV), disordered erythropoiesis triggers severe pathophysiological manife

278 During erythropoiesis, Trim58 expression, dynein loss, and enuc

279 Here we investigated regulation of erythropoiesis using a ligand-trapping fusion protein (A

280 s RBC production, we comprehensively studied erythropoiesis using knockout mice and hematopoietic pro

281 and GATA1, and functional connections during erythropoiesis using these dynamic networks, while the t

282 ocytic anemia and activation of compensatory erythropoiesis via the regulators erythropoietin and ery

283 the cDC1 subset to the initiation of stress erythropoiesis was distinct from the well-recognized rol

284 Erythropoiesis was increased in the bone marrow and sple

285 partmental model of mouse thrombopoiesis and erythropoiesis was set up to predict the depletion of he

286 this pivotal work, the role of the kidney in erythropoiesis was shown by Leon Jacobson in 1957 and er

287 Erythropoiesis was suppressed between days 1 and 7, and

288 an stress erythropoiesis is similar to fetal erythropoiesis, we demonstrate that human stress erythro

289 To selectively investigate primitive erythropoiesis, we have engineered a new transgenic embr

290 the mechanism by which lenalidomide promotes erythropoiesis, we investigated its action on erythropoi

291 Because autophagy is also important in erythropoiesis, we studied in vitro CD34(+)-derived eryt

292 roleukemia cells, knockdown of LPA2 enhanced erythropoiesis, whereas knockdown of LPA3 inhibited RBC

293 glycero-3-phosphothionate (2S-OMPT) promoted erythropoiesis, whereas the LPA2 agonist dodecyl monopho

294 a are characterized by defects in late-stage erythropoiesis, which is EPO independent.

295 in RBC survival, hemolysis, and insufficient erythropoiesis, which is evident from a significant decr

296 xia-induced and HIF-mediated augmentation of erythropoiesis, which provides a molecular mechanism for

297 ionally, mtClpX depletion impairs vertebrate erythropoiesis, which requires massive upregulation of h

298 ddition, the humanized mice display abnormal erythropoiesis, which was reported to associate with dep

299 novel regulatory relationships activated in erythropoiesis, which were further validated by genome-w

300 xygen transport, and hypoxia signaling links erythropoiesis with iron homeostasis.