ライフサイエンスコーパス: erythrose

1 in a yield of 3.5% based on the ratio of His/erythrose.

2 A new d-erythrose 1,3-dioxane derivative was synthesized from d-

3 rom easily accessible 2,3-O-isopropylidene-d-erythrose (2b), and the combination of a strategic intra

4 We show that epd (gapB) mutants lacking an erythrose 4-phosphate (E4P) dehydrogenase are impaired f

5 value was inconsistent with the formation of erythrose 4-phosphate (E4P) exclusively by the carboxyla

6 densation of phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) with the formation of DAHP.

7 ding aldose: arabinose 5-phosphate (A5P) and erythrose 4-phosphate (E4P), respectively.

8 osphate (R5P) nor the four carbon analogue D-erythrose 4-phosphate (E4P).

9 vate (PEP), arabinose 5-phosphate (A5P), and erythrose 4-phosphate (E4P).

10 zes the isomerization of DXP to 2-C-methyl-D-erythrose 4-phosphate (MEsP) and subsequent NADPH-depend

11 hosphoenolpyruvate = 9.5-13 microm, Km for d-erythrose 4-phosphate = 57.3-350.1 microm, and kcat = 2.

12 s two natural substrates and two inhibitors, erythrose 4-phosphate and mannitol 1-phosphate, were inv

13 DAH 7-P synthase for its normal substrates D-erythrose 4-phosphate and PEP and provide direct evidenc

14 zyme does not catalyze the condensation of D-erythrose 4-phosphate and phosphoenolpyruvate to form 3-

15 of DAH7P synthase the two substrates PEP and erythrose 4-phosphate appear to bind in a configuration

16 cation with transketolase, which increases d-erythrose 4-phosphate availability, afforded 16 g/L 3-de

17 icular, [6-13C]hexose 6-phosphate and [4-13C]erythrose 4-phosphate carbon enrichment values resulting

18 e inferred intermediacy of 1-deoxy-1-imino-D-erythrose 4-phosphate in Amycolatopsis mediterranei cell

19 Erythrose 4-phosphate is epimerized and/or isomerized to

20 activation by phosphoenolpyruvate, whereas d-erythrose 4-phosphate offers only minimal protection.

21 he step(s) from either phosphoenolpyruvate/d-erythrose 4-phosphate or other precursors to 3,4-dideoxy

22 L-3-tetrulose-4-phosphate was converted to D-erythrose 4-phosphate through three previously unknown i

23 ldol condensation of phosphoenolpyruvate and erythrose 4-phosphate to form 3-deoxy-D-arabino-heptulos

24 the condensation of phosphoenolpyruvate, and erythrose 4-phosphate to form 3-deoxy-D-arabino-heptulos

25 in catalyzing the addition of pyruvate to d-erythrose 4-phosphate to form DAHP.

26 ments show that threitol is synthesized from erythrose 4-phosphate, a C(4) intermediate in the PPP.

27 ng carbohydrate metabolism exclusively via D-erythrose 4-phosphate, a pathway that may provide clues

28 ative form and in complex with the inhibitor erythrose 4-phosphate, and with the substrate glucose 6-

29 obtained label via the chorismate route from erythrose 4-phosphate, generated via the pentose phospha

30 nolpyruvate and d-arabinose 5-phosphate or d-erythrose 4-phosphate, respectively.

31 eavage of the ribityl tail to form DMB and D-erythrose 4-phosphate.

32 hat the product formed by KDOP synthase with erythrose-4-P as the substrate was 3-deoxy-D-ribo-heptul

33 f the ability of KDOP synthase to substitute erythrose-4-P for arabinose-5-P is (i) recognition of th

34 ability to replace arabinose-5-P with either erythrose-4-P or ribose-5-P as alternative substrates.

35 Based on the precedent of the d-erythrose-4-phosphate (E4P) modeled in the active site o

36 densation of phosphoenolpyruvate (PEP) and d-erythrose-4-phosphate (E4P) with the formation of DAHP.

37 The S0.5 was 35 microM for erythrose-4-phosphate and 5.3 microM for phosphoenolpyru

38 Phe, the enzyme loses the ability to bind D-erythrose-4-phosphate and binds phosphoenolpyruvate in a

39 rbolic mixed-type inhibition with respect to erythrose-4-phosphate and partial noncompetitive inhibit

40 ,4-DHB (1) involved phosphoenol pyruvate and erythrose-4-phosphate as ultimate precursors.

41 ne in Vibrio cholerae (epd) which encodes an erythrose-4-phosphate dehydrogenase activity and is loca

42 D-erythrose-4-phosphate is then converted by enzymes of th

43 sphate isomerase; renamed EryH), and RpiB (D-erythrose-4-phosphate isomerase; renamed EryI), a pathwa

44 the condensation of phosphoenolpyruvate and erythrose-4-phosphate to form 3-deoxy-D-arabino-heptulos

45 ke condensation of phosphoenolpyruvate and D-erythrose-4-phosphate with the formation of 3-deoxy-D-ar

46 tolase activity is required in cells to make erythrose-4-phosphate, a precursor of aromatic amino aci

47 is shown to interfere with the production of erythrose-4-phosphate, which is essential for the first

48 tent with the isotopomer distribution of the erythrose-4-phosphate-derived amino acids phenylalanine

49 ation of DAHP from phosphoenolpyruvate and D-erythrose-4-phosphate.

50 ctivated the enzyme at low concentrations of erythrose-4-phosphate.

51 Mode of action studies with the D-erythrose analogues established that 8b acted by inhibit

52 o measured with the alternative substrates D-erythrose and D-ribose, making SalM the first reported s

53 round by employing a combination of [4-(13)C]erythrose and deuterated pyruvate during growth on deute

54 etaldehyde took place by the condensation of erythrose and formamidine, two compounds that are known

55 phate, glyceraldehyde 3-phosphate, ribulose, erythrose, and sucrose as potential precursors of plant

56 the sodA sodB strain against the toxicity of erythrose as did the carbonyl-blocking reagents hydrazin

57 Erythrose inhibited the growth of a sodA sodB strain of

58 Third, glyceraldehyde- and erythrose-labeling studies showed increased incorporatio

59 hibition led to increased glyceraldehyde and erythrose levels in the cell.

60 on converted fructose plus glyceraldehyde to erythrose plus xylulose, the same products as are formed

61 derived from dihydroxyacetone phosphate and erythrose via an aldolase reaction.

62 The asymmetric effect is largest for erythrose, which may reach a D-enantiomeric excess of >8

63 complished experimentally by the reaction of erythrose with formamidine followed by a Strecker synthe

64 increased activity for the aldol reaction of erythrose with pyruvate compared with the wild-type enzy