ライフサイエンスコーパス: essential amino acid

1 Tryptophan is an essential amino acid.

2 sing the abundance of methionine, a limiting essential amino acid.

3 indicated that PhtA transports threonine, an essential amino acid.

4 h concentration of lysine, the most limiting essential amino acid.

5 f the eight strands contributes at least one essential amino acid.

6 pplementation even though glutamine is a non-essential amino acid.

7 e, which identified Pro, Leu, and Cys as the essential amino acids.

8 especially Threonine and Tryptophan than non essential amino acids.

9 o increase majority of the essential and non-essential amino acids.

10 incipal source of nutrition, particularly of essential amino acids.

11 unexpected new roles, functional domains and essential amino acids.

12 urposes of the host, namely the synthesis of essential amino acids.

13 in of mice restricts intake of diets lacking essential amino acids.

14 edominant cellular pathway for the uptake of essential amino acids.

15 and phenylalanine being the most affected of essential amino acids.

16 retains capabilities for biosynthesis of all essential amino acids.

17 l cycle protein expression in the absence of essential amino acids.

18 roteinuria is a stimulus to conserve dietary essential amino acids.

19 lism such as low alanine levels and elevated essential amino acids.

20 Surprisingly, PDAC accumulated essential amino acids.

21 ut had no effect on those of the majority of essential amino acids.

22 ty leads to changes in the metabolism of non-essential amino acids.

23 ic non-protein amino acids and the levels of essential amino acids.

24 CPHs had similar and adequate quantities of essential amino acids.

25 al supplementation with whey protein (22 g), essential amino acids (10.9 g, including 4 g leucine), a

26 All portions contained a large amount of essential amino acids (167.66-187.63 mg/g sample), in wh

27 kg(-1) . d(-1) and 6.77 g of a mixture of 5 essential amino acids 3 times/d (leucine, isoleucine, va

28 (48%), essential fatty acids (23-100%), and essential amino acids (34-67%) available for human consu

29 s contained measurable quantities of 9 of 10 essential amino acids (41.62-63.50% of the total amino a

30 otein hydrolysate contained a high amount of essential amino acids (48.22%) and had arginine and lysi

31 amino acid content was 91.90+/-7.70% mainly essential amino acids (55.87+/-2.15mgg(-1)) which were c

32 rter often required for tumor cell import of essential amino acids (AA) including Methionine (Met).

33 ized by simultaneous glutamine depletion and essential amino acid accumulation.

34 We previously showed that free-form essential amino acids acutely stimulate muscle protein s

35 mutations in gene 2.5 uncovered a variety of essential amino acids, among which was a single amino ac

36 Leucine, as an essential amino acid and activator of mTOR (mammalian ta

37 l-Methionine is an essential amino acid and is required for protein synthes

38 ource of protein with high levels of several essential amino acids and a good nutritional value.

39 ls overcome their dependence on supplemented essential amino acids and can be selectively labeled thr

40 results in increased intracellular levels of essential amino acids and enhanced mTORC1 signalling, pr

41 lude a sharp reduction in the degradation of essential amino acids and protein; changes in protein sy

42 ls grow indefinitely in media lacking single essential amino acids and replicate once in the absence

43 Both the supply of essential amino acids and the bioactivities of milk prot

44 a genetic program for the cellular uptake of essential amino acids and the synthesis of nonessential

45 ts are proline, chlorophyll A and B, all the essential amino acids and vitamin A, E and C.

46 tivates the UPS and autophagy, which provide essential amino acids and, together with the enhanced ub

47 ow protein diet (0.3 g/kg) plus supplemental essential amino acids and/or ketoacids and followed clos

48 ing of specific nutrients (e.g., B vitamins, essential amino acids) and modulation of the insect nutr

49 13%, lowered fetal plasma concentrations of essential amino acids, and decreased the phosphorylation

50 nolamine lipid structures, essential and non-essential amino acids, and metabolites involved in polya

51 Supplementation with whey protein, essential amino acids, and vitamin D, in conjunction wit

52 vidence is insufficient to determine whether essential amino acids are affected by varying gluconeoge

53 transcription factor DNA-binding sites, and essential amino acids are revealed by the nucleotide fle

54 In aphids, the 10 essential amino acids are scarce in the phloem sap diet

55 act in the M. sexta midgut to catabolize the essential amino acids Arg and Thr, respectively.

56 netic analysis of mutational effects at four essential amino acids: Arg-130, Gly-132, Tyr-136 and Lys

57 ition model in which the accumulation of the essential amino acid arginine in A. pisum hemolymph redu

58 Transport of the essential amino acids arginine and lysine is critical fo

59 porter, Cat-1, facilitates the uptake of the essential amino acids arginine and lysine.

60 Cat-1, the transporter for the essential amino acids, arginine and lysine, is one of th

61 Cat-1, is a high affinity transporter of the essential amino acids, arginine and lysine.

62 oteobacteria), can produce the remaining two essential amino acids as well as many vitamins.

63 These studies help to define essential amino acids at or near the nucleotide-binding

64 buting to nutrition, especially by providing essential amino acids, B vitamins, and, for fungal partn

65 ed antimicrobials based on dual targeting of essential amino acid biogenesis and its linkage to cell

66 lic processes promoting colonization include essential amino acid biosynthesis and iron acquisition p

67 ene sets conferring similar capabilities for essential amino acid biosynthesis, in both cases precise

68 ugh Buchnera's genome encodes most genes for essential amino acid biosynthesis, several genes in esse

69 Supplementation with essential amino acids blunts the fructose-induced increa

70 We hypothesized that protein, essential amino acid, branched-chain amino acid, and leu

71 Neither essential amino acids, branched-chain amino acids, nor a

72 Nutrient deprivation based on the loss of essential amino acids by catabolic enzymes in the microe

73 ork has focused on identifying catalytically essential amino acids by mutagenesis of Bacillus megater

74 The metabolism of dietary essential amino acids by the gut has a direct effect on

75 The gonads were rich in essential amino acids (ca. 32.1% of total amino acids) w

76 Nutrition' group ingested a leucine-enriched essential amino acid-carbohydrate mixture (EAC).

77 ere is a coordinated increase in protein and essential amino acid catabolism.

78 he functionality of PR without affecting the essential amino acid composition.

79 p between the fold increase in MPS and blood essential amino acid concentration ([EAA], mM) was hyper

80 Prosopis alba proteins, are not deficient in essential amino acids considering the amount of amino ac

81 Similarly, essential amino acid content was also higher in placenta

82 a have been established in relation to their essential amino acid contents, protein richness, digesti

83 trongly reduced the lysosomal efflux of most essential amino acids, converting the lysosome into a ce

84 We predict that nonessential and essential amino acids correspond to these nutrient class

85 In aphids, the supply of essential amino acids depends on an ancient nutritional

86 roxide dismutase expression mediated through essential amino acid depletion concurrent with an increa

87 However, essential amino acids derive only from the larval diet,

88 (Bacteroidetes), can produce eight of the 10 essential amino acids, despite having a genome of only 2

89 Arginine is considered an essential amino acid during critical illness in children

90 of transceptor for sensing and transporting essential amino acids during mosquito reproduction.

91 nhance the muscle protein anabolic effect of essential amino acid (EAA) + sucrose intake in older sub

92 The essential amino acid (EAA) density of a food also emerge

93 fusion in the postabsorptive state and after essential amino acid (EAA) ingestion on three occasions:

94 The effects of essential amino acid (EAA) supplementation during modera

95 pecifically activated by deficiencies in any essential amino acid (EAA); EAA deficiency leads to rapi

96 s subsequent rapid efflux in the presence of essential amino acids (EAA) is the rate-limiting step th

97 synthesis represented as a function of five essential amino acids (EAA).

98 ry insufficiencies of macronutrients such as essential amino acids (EAA).

99 Dietary protein provides essential amino acids (EAAs) for the synthesis of new pr

100 Essential amino acids (EAAs) have been shown to attenuat

101 Restricting availability of essential amino acids (EAAs) limits aminoacylation of tR

102 of enzymes that consume at least 5 different essential amino acids (EAAs).

103 cle proteins after a bolus ingestion of 15 g essential amino acids (EAAs).

104 is affected by the presence of the remaining essential amino acids (EAAs).

105 Lysine, a nutritionally essential amino acid, enters the oral cavity in gingival

106 analysis revealed a higher concentration of essential amino acids especially Threonine and Tryptopha

107 letion (TD) induced by oral loading with all essential amino acids except the serotonin precursor try

108 (14.5%) and encompassed adequate amounts of essential amino acids, fatty acids and minerals.

109 Cysteine is an essential amino acid for B. pertussis and must be presen

110 This enzyme decarboxylates lysine, an essential amino acid for dentally attached cell turnover

111 l-Methionine (Met) is an essential amino acid for humans and is important for pro

112 alism in which each yeast strain supplies an essential amino acid for its partner strain.

113 ps such as rice, as methionine is a limiting essential amino acid for mammalian diets.

114 Although arginine is not an essential amino acid for most cells, all human melanomas

115 Arginine is an essential amino acid for normal T-cell function whose av

116 eucine (an activator of mTOR), glutamine (an essential amino acid for nucleotide biosynthesis and sub

117 Cysteine is an essential amino acid for T-cell activation because T cel

118 strate for glutaminolysis), and arginine (an essential amino acid for tumor cells), suggesting that E

119 41, A342, and R343 on the CD26 molecule were essential amino acids for ADA binding.

120 lant-based proteins can provide the required essential amino acids for health, animal proteins genera

121 his is exemplified by methionine, one of the essential amino acids for humans, which needs to be acti

122 Glu83 and E134 are essential amino acids for SULT1A1 catalytic activity.

123 Essential amino acids for this catalytic activity were i

124 on of Slif are consistent with conveyance of essential amino acids from gut to fat body.

125 se of the cell cycle that are dependent upon essential amino acids, Gln, and finally, a checkpoint me

126 Dividing cells rely on the "conditionally essential" amino acid glutamine (Q) as an anaplerotic ca

127 ate, cancer cells rely on the 'conditionally essential' amino acid glutamine (Q) as an anaplerotic ca

128 The non-essential amino acid, glutamine, exerts pleiotropic effe

129 Furthermore, in HCT116 cells two non-essential amino acids, glutamine and serine, which are o

130 Auxotrophic for 8 of the 10 essential amino acids, H. defensa is reliant upon the es

131 Specifically, bacterial provisioning of essential amino acids has been demonstrated.

132 an interaction between methionine and other essential amino acids having a key role.

133 Its proteins are a good source of essential amino acids; however, there are no reports on

134 ntinuous supply of all of the indispensable (essential) amino acids (IAAs).

135 onessential amino acids Gly and Glu, and the essential amino acid Ile were more abundant in the scalp

136 Arginine, a semiessential or conditionally essential amino acid in humans, is one of the most metab

137 Methionine is an essential amino acid in mammals at the junction of methy

138 equate provision of glycine, a conditionally essential amino acid in pregnancy, may play a role in th

139 Taurine is an essential amino acid in some mammals and is conditionall

140 se activity with maribavir or mutation of an essential amino acid in the kinase abolished its ability

141 This approach to identifying essential amino acids in a protein of interest introduce

142 there are also defects in the metabolism of essential amino acids in ARF, we measured the activity o

143 thways associated with the production of non-essential amino acids in Haemophilus influenzae were com

144 in amino acids (BCAAs) are three of the nine essential amino acids in human and animal diets and are

145 activity is required for the biosynthesis of essential amino acids in plants and microorganisms.

146 red for the biosynthesis of one fifth of the essential amino acids in plants and microorganisms.

147 of IUGR, we found reduced concentrations of essential amino acids in the experimental dams.

148 Here we demonstrate that essential amino acids, in particular branched-chain amin

149 the epithelial uptake and redistribution of essential amino acids including precursors of several ne

150 c1-dependent macropinocytosis to provide non-essential amino acids, including asparagine.

151 RNA cleavage is inhibited in the presence of essential amino acids, independent of the persistence of

152 Overloading the medium with non-essential amino acids induced apoptosis, but essential a

153 Limiting any essential amino acid initiates this signaling cascade, w

154 46, which corresponds to P450cam-Thr-252, an essential amino acid involved in dioxygen bond scission,

155 atomic model for each map and identified an essential amino acid involved in genome encapsidation.

156 ein (HP) diet], more than half the intake of essential amino acids is metabolized by the portal-drain

157 defined medium where the only source of the essential amino acid isoleucine was from peptides of var

158 Although administration of the essential amino acid L-arginine has been reported to res

159 The product of the reaction is the essential amino acid l-lysine, which is an important pre

160 Since depletion of the essential amino acid L-tryptophan (Trp) affects immune r

161 Since depletion of the essential amino acid L-tryptophan (Trp) severely affects

162 ate-limiting enzyme in the catabolism of the essential amino acid L-tryptophan.

163 We show that withdrawal of essential amino acids leads to an increase in cytosolic

164 ) is a key enzyme in the biosynthesis of the essential amino acid leucine, and thus primary metabolis

165 Transport of the essential amino acids leucine and tryptophan into bovine

166 On the other hand, essential amino acids (leucine in particular) and insuli

167 Five essential amino acids (leucine, lysine, methionine, thre

168 Essential amino acid levels in all insect species were c

169 ted arginine deiminase (ADI-PEG 20) depletes essential amino acid levels in argininosuccinate synthet

170 PD regimen significantly reduced insulin and essential amino acid levels, and increased glucose level

171 Essential amino acids like lysine and tryptophan are def

172 tural source of antioxidant insoluble fibre, essential amino acids, low glycaemic sugars, resistant t

173 cause its storage proteins are devoid of the essential amino acid lysine (Lys).

174 roteins may contain up to 43% mol/mol of the essential amino acid lysine.

175 retrovirus as a membrane transporter for the essential amino acids lysine and arginine was a landmark

176 e gene (CGS), to improve the contents of the essential amino acids lysine and methionine.

177 onutrients (provitamin A and folates) and an essential amino acid (lysine) in three major cereal grai

178 ured the generation of higher levels of free essential amino acids; lysine, phenylalanine and arginin

179 Thus, genes encoding the uptake of essential amino acids may well represent novel targets f

180 The essential amino acid methionine can be used for protein

181 dictor of maternal tHcy (P < 0.001) when the essential amino acid methionine was low.

182 alamin biosynthetic capabilities to make the essential amino acid methionine.

183 In an attempt to increase the content in essential amino acids methionine and tryptophan of the t

184 modeled have lost biosynthetic pathways for essential amino acids methionine, tryptophan, or leucine

185 An essential amino acid motif (DGXD) containing aspartate r

186 Essential amino acid muscle loss was also significantly

187 in the diet can affect the oxidation of some essential amino acids, namely leucine.

188 Arginine is an essential amino acid necessary for protein synthesis and

189 about 10% is devoted to the biosynthesis of essential amino acids needed by its hosts.

190 ivation to the release from lysosomes of the essential amino acids needed to drive cell growth.

191 We utilized this finding to identify the essential amino acids of EF-Tu(Mp) that mediate Fn inter

192 ics of fully deuterated Val80 and Val84, two essential amino acids of the dimerization motif.

193 interactions in DNA transfer and to identify essential amino acids of VirB8, we introduced random mut

194 If uremia prevents suppression of essential amino acid or protein degradation when dietary

195 protein were still uncertain, and those for essential amino acids or essential fatty acids were unkn

196 t, in an arginine-regulated fashion, of many essential amino acids out of lysosomes, including leucin

197 essential amino acids induced apoptosis, but essential amino acid overloading partially ameliorated a

198 al amino acid biosynthesis, several genes in essential amino acid pathways are missing, as are most g

199 trient production between symbionts, several essential amino acid pathways in the mealybug assemblage

200 -regulated genes fill the gaps of Buchnera's essential amino acid pathways.

201 ignificantly decreased concentrations of the essential amino acid phenylalanine and the essential bra

202 ynthesis, which spans diverse metabolisms of essential amino acids, phenylpropanoids, benzenoids, and

203 nning mutations identified important but not essential amino acid positions.

204 The addition of essential amino acids potentiates the synthetic response

205 growth advantage to the bacterium, providing essential amino acid precursors by initiating the degrad

206 amino acids, H. defensa is reliant upon the essential amino acids produced by Buchnera.

207 s fraction (AF) obtained by EAE had a better essential amino acid profile than the residues obtained

208 rnitine, spermidine, and the total amount of essential amino acids, provided significant prognostic v

209 previously that depriving cells of a single essential amino acid rapidly and reversibly arrests puri

210 The essential to non-essential amino acid ratio was 0.5.

211 The branched-chain amino acids (BCAA) are essential amino acids required for protein homeostasis,

212 acid studies with the goal of assessing the essential amino acid requirements for egg production.

213 was conducted in an attempt to identify this essential amino acid residue in order to further define

214 The three catalytically essential amino acid residues (Asp110, Asp185, and Asp18

215 All essential amino acid residues for substrate binding foun

216 ain new information concerning catalytically essential amino acid residues in DIPP.

217 Identification of essential amino acid residues of these proteases suggest

218 It also provides information on the essential amino acid residues that determine donor subst

219 of this transporter have been identified as essential amino acid residues that probably function as

220 Together, these data demonstrate that two essential amino acid residues within a four-amino acid s

221 In summary, we have identified three essential amino acid residues within the N-terminal regi

222 Among these essential amino acid residues, we find that residues Arg

223 the reaction intermediates and catalytically essential amino acid residues.

224 nd to be the most abundant essential and non-essential amino acids, respectively.

225 fication of Leu(480) and Gln(481) as the two essential amino acids responsible for the enhanced activ

226 d brain leucine accumulation displaces other essential amino acids resulting in neurotransmitter depl

227 When the four essential amino acids (RWFV) were either substituted en

228 The non-essential amino acids serine and glycine are used in mul

229 mportant because serum concentrations of the essential amino acids should not be lower than those in

230 90 minutes during the middle of a 270-minute essential amino acid solution infusion (which stimulates

231 rotein macropinocytosis can also serve as an essential amino acid source.

232 Here we link essential amino acid starvation and Ca(2+) in a signalin

233 an intravenously administered mixture of 10 essential amino acids stimulated insulin secretion.

234 Vps34 activity is stimulated by an influx of essential amino acids such as leucine and this may prolo

235 PBPI was found to obtain high amount of essential amino acids such as leucine, lysine, and pheny

236 profile of PFCP showed a high percentage of essential amino acids, such as arginine, lysine, histidi

237 We report here that limitation of essential amino acids, such as methionine and cysteine,

238 e mineral elements, such as K, Ca and P, and essential amino acids, such as tryptophan, valine, and t

239 ptad repeats, and 3-4-residue spacing of the essential amino acids suggest that residues 37-52 adopt

240 of this study was to evaluate the effect of essential amino acid supplementation on the increase in

241 inhibitor 3-methyladenine was alleviated by essential amino acid supplementation.

242 How immune cells integrate information about essential amino acid supplies and then transfer these si

243 In contrast, protein catabolism and essential amino acid synthesis pathways in baleen whale

244 The essential amino acid taurine has important physiologic a

245 e that supplementation with L-methionine, an essential amino acid that assists in the metabolism of h

246 Tryptophan is an essential amino acid that is required for normal develop

247 Methionine was the only essential amino acid that rapidly induced PGC-1alpha ace

248 hids and Buchnera aphidicola, which produces essential amino acids that are rare in the phloem sap di

249 uided mutagenesis of Msl5 distinguished four essential amino acids that contact the BP sequence from

250 oretic profile, showing a suitable amount of essential amino acids that covers the recommended daily

251 ids (BCAAs) Leu, Ile, and Val are among nine essential amino acids that must be obtained from the die

252 s (BCAAs) valine, leucine and isoleucine are essential amino acids that play critical roles in animal

253 Because tryptophan is an essential amino acid, these findings suggest that a phys

254 re elevated importation of essential and non-essential amino acids to generate large numbers of daugh

255 Adding essential amino acids to the dietary restriction conditi

256 ne were the least abundant essential and non-essential amino acids to with 0.23 g methionine and 0.36

257 ferent species to increase the levels of the essential amino acid Trp and impart 5MT resistance.

258 By catabolizing the essential amino acid TRP, cells expressing the enzyme in

259 its T-cell proliferation by catabolizing the essential amino acid tryptophan (Trp) into the kynurenin

260 oxygenase (IDO) catalyses degradation of the essential amino acid tryptophan into immunomodulatory me

261 It has been proposed that the essential amino acid tryptophan is catabolized in the tu

262 Local catabolism of the essential amino acid tryptophan is considered an importa

263 In mammalian cells, the essential amino acid tryptophan is degraded primarily by

264 inhibition is the result of depletion of the essential amino acid tryptophan via the IFN-gamma-induce

265 malarial drug quinine perturbs uptake of the essential amino acid tryptophan, and patients with low p

266 ough melatonin is a direct derivative of the essential amino acid tryptophan, little is known about t

267 ase (IDO), which depletes local pools of the essential amino acid tryptophan, resulting in blockade o

268 The essential amino acids: tryptophan, isoleucine, valine, p

269 , lysine, histidine, methionine, and the non-essential amino acids: tyrosine, 4-hyrdroxy proline, arg

270 We examined 20 essential and non-essential amino acids using the ORAC assay and used a si

271 Here we report that the essential amino acid valine is indispensable for the pro

272 Contents of essential and non-essential amino acids varied in the range of 22.8-42.3 a

273 ntly, Blattabacterium can produce all of the essential amino acids, various vitamins, and other requi

274 of total free amino acids, essential and non-essential amino acids were 199.65 mg/100 g, 113.69 mg/10

275 alanine) were present and the most abundant essential amino acids were arginine, leucine, lysine and

276 ular concentrations of essential but not non-essential amino acids were decreased by bafilomycin in E

277 The average concentrations of protein and essential amino acids were higher in the muscle than in

278 ity of the mutant enzymes, six catalytically essential amino acids were identified: Trp-11, Asp-66, T

279 The most abundant essential amino acids were Thr (5.7%), Val (6.0%), Ile (

280 nactivated topoisomerase II by alkylation of essential amino acids, whereas the mechanism of inhibiti

281 of enzyme protein and overproduction of this essential amino acid, which is required by the aphid hos

282 s depends on intracellular concentrations of essential amino acids, which are maintained by a specifi

283 precursor of SAMe is methionine, one of the essential amino acids, which is activated by SAMe-synthe

284 oles of these enzymes in the biosynthesis of essential amino acids within the plastid.