ライフサイエンスコーパス: essential component

1 ducation and assessment of performance is an essential component.

2 demonstrate here that ExsY forms one of the essential components.

3 HLAMatchmaker algorithm considers eplets as essential components.

4 We identified 53BP1 and USP28 as essential components acting upstream of p53, evoking p21

5 Previous work identified VE-cadherin as an essential component, along with PECAM-1 and VEGFR2, of a

6 Autophagy provides essential components (amino acids, lipids, and carbohydr

7 voltage-dependent anion channel 2 (VDAC2) as essential component and platform for Bax retrotranslocat

8 Our strategy effectively utilizes the three essential components dictating living tissue morphogenes

9 sing a treatment protocol that includes five essential components: eligibility criteria, down-staging

10 that Pop1/Pop6/Pop7 function to maintain the essential components Est1 and Est2 on the RNA in vivo.

11 ne LD coat protein is caveolin-1 (Cav-1), an essential component for caveola assembly in highly diffe

12 tein-coupled receptor kinase 2 (Gprk2) as an essential component for enriching PI(4)P and facilitatin

13 hosphorylation state of serines is likely an essential component for the integrity of AMBN function.

14 es H2O2-induced covalent modifications as an essential component for the peroxidase activity of "nati

15 lating evidence shows that proteoglycans are essential components for chondrocyte proliferation and d

16 pregulation of elastin and collagen 2A1, two essential components for healthy skin.

17 The temporal lack of one of these essential components for microbial activity, arising fro

18 otropic GABAA receptors (GABAARs), but their essential components for synaptic localization remain un

19 Distributed Bragg reflectors (DBRs) are essential components for the development of optoelectron

20 g errors and PCR artifacts has emerged as an essential component in amplicon-based metagenomic studie

21 ate and high-fidelity broadband pulses is an essential component in conducting quantum experiments ac

22 tablish the epigenetic regulator ZBTB4 as an essential component in maintaining genomic stability in

23 ssive mutations in POMGNT1, which encodes an essential component in O-mannosylation pathway, in three

24 Perforin is an essential component in the cytotoxic lymphocyte-mediated

25 Access to appropriate diagnostic tools is an essential component in the evaluation and improvement of

26 gh the fractalkine receptor CX3CR1 is not an essential component in the mechanisms of visual cortical

27 to periodic bursting in pyramidal cells, an essential component in the onset of ictal epileptic even

28 Cs and DSGCs underlies the development of an essential component in the retina's direction selective

29 artments and bilayers, and as such are truly essential components in all cells and in many cellular p

30 Proteins are essential components in many food processes, and provide

31 logy which can be used for the extraction of essential components in Moringa oleifera leaf extracts.

32 Nanoscale emulsions are essential components in numerous products, ranging from

33 Avalanche photodiodes (APDs) are essential components in quantum key distribution systems

34 Moreover, they are essential components in the assimilation of extracellula

35 stone variants and histone modifications are essential components in the establishment and maintenanc

36 sentation of major oceanic fronts, which are essential components in the simulation and prediction of

37 mitochondrial membrane that consists of two essential components, MPC1 and MPC2.

38 apical proteins in T. gondii and identify an essential component named conoid protein hub 1 (CPH1), w

39 Folic acid is an essential component of 1-carbon metabolism, which genera

40 These results establish Coronin-1 as an essential component of a feedback loop that mediates NGF

41 Smoking cessation is an essential component of a high-quality screening program.

42 protein homologous to NuMA and LIN-5, is an essential component of a Netrin-independent pathway that

43 r distribution protein C (nudC), which is an essential component of a specialized dynein complex that

44 ant regulator of stem cell activation and an essential component of a transcriptional complex that su

45 The anionic lipid cardiolipin is an essential component of active ATP synthases.

46 ase in airway smooth muscle (ASM) mass is an essential component of airway remodeling in patients wit

47 Because cholesterol is an essential component of all cellular membranes, some FC m

48 ction of TraE, a homolog of VirB8 that is an essential component of all T4SSs.

49 An essential component of allogeneic and autologous hematop

50 to the synthesis of l-iduronic acid being an essential component of anticoagulant drugs with diastere

51 KREPB5 is an essential component of approximately 20S editosomes in T

52 tation (CR) and risk reduction program is an essential component of ASCVD prevention and management.

53 e central nucleus of the amygdala (Ce) as an essential component of AT's neural substrates.

54 eoxy-d-manno-oct-2-ulosonic acid (Kdo) is an essential component of bacterial lipopolysaccharides, wh

55 Prevention is an essential component of cancer eradication.

56 ion (IR) and/or cytotoxic chemotherapy is an essential component of cancer therapy.

57 Patient education is believed to be an essential component of cardiovascular care; however, the

58 Caveolin-1 (CAV1) is an essential component of caveolae and is implicated in num

59 Cholesterol is an essential component of cell membranes and is required fo

60 based not on prognosis but on need and is an essential component of comprehensive care for critically

61 Palliative care is now recognized as an essential component of comprehensive care in serious ill

62 truments, such as endoscopes, have become an essential component of contemporary medicine.

63 ent ribosome-targeting antibiotic that is an essential component of current antituberculosis treatmen

64 such as UniProtKB/Swiss-Prot, constitute an essential component of daily scientific research by offe

65 gest multiplex paper-based devices can be an essential component of diagnostic assays used at the poi

66 ly laboratory confirmation of infections, an essential component of disease surveillance systems.

67 iature chromosome maintenance 7 (MCM7) is an essential component of DNA replication licensing complex

68 Thus, Lin37 is an essential component of DREAM that cooperates with Rb to

69 provide limited financial value, they are an essential component of ecosystem functioning by offering

70 tous lipid-soluble redox cofactor that is an essential component of electron transfer chains.

71 T-cell-specific deletion of dynamin 2, an essential component of endocytosis, resulted in reduced

72 occurring microbial cellular densities is an essential component of environmental systems monitoring.

73 on at CpG dinucleotides in a cell remains an essential component of epigenetic profiling.

74 ogether, our findings reveal that CBX6 is an essential component of ESC biology that contributes to t

75 nes; spermidine (Spd) and spermine (Spm) are essential component of every cell because of their invol

76 roducing enzyme in the human platelet, is an essential component of FcgammaRIIa-mediated thrombosis.

77 Inhibition of glutaminolysis, the essential component of ferroptosis, can reduce heart inj

78 methylation of histone lysine residues is an essential component of gene expression regulation and th

79 An essential component of goal-directed decision-making is

80 Thus, chromatin remodeling is an essential component of GR-mediated transcriptional regul

81 An essential component of HBV is the spherical capsid compo

82 Surgical care is an essential component of health management worldwide.

83 he glycine-tryptophan protein of 182 kDa, an essential component of HMW-RISC, and improved the abilit

84 Working memory is an essential component of human cognition.

85 Rab3A is an essential component of human sperm exocytotic machinery.

86 regression, we considered whether Erk was an essential component of IGF-dependent stabilization.

87 nal-regulated kinase signaling pathway is an essential component of innate immunity necessary for med

88 Autophagy is an essential component of innate immunity, enabling the det

89 Using biological control agents (BCAs) is an essential component of integrated pest and diseases mana

90 therefore, constraint of this pathway is an essential component of its regulation.

91 Apolipoprotein E (apoE) is an essential component of lipoprotein particles in both the

92 ventral mesencephalic dopamine neurons as an essential component of locomotor activation, we hypothes

93 od and are present in lymphoid organs are an essential component of long-lived T cell immunity.

94 eoxy-d-manno-oct-2-ulosonic acid (Kdo) is an essential component of LPS in the outer leaflet of the G

95 eration of the anaphylatoxin C5a and C5b, an essential component of MAC.

96 Public transportation systems are an essential component of major cities.

97 Asymmetric partitioning is an essential component of many developmental processes.

98 Iron is an essential component of many important proteins and enzym

99 AR)-2-dependent inflammatory signaling as an essential component of matriptase-mediated oncogenesis.

100 Retention in care is an essential component of meeting the UNAIDS "90-90-90" HIV

101 ity, realize the importance of support as an essential component of men's adaptation post-prostatecto

102 13C flux analysis studies have become an essential component of metabolic engineering research.

103 sity (LOH) in beta-2-microglobulin (B2M), an essential component of MHC class I antigen presentation,

104 tion of dynamin-related protein 1 (Drp1), an essential component of mitochondrial fission, on the pat

105 The resources have become essential component of modern plant science.

106 he bacterial cell wall is a highly conserved essential component of most bacterial groups.

107 Rictor, an essential component of mTOR complex 2 (mTORC2), plays a

108 is-specific loss of Raptor, which encodes an essential component of mTORC1, confers the same skin phe

109 Conversely, targeted mutation of Raptor, an essential component of mTORC1, increased miRNA biogenesi

110 s with an epidermal deficiency of Rictor, an essential component of mTORC2, survive despite a hypopla

111 molecules that bind to the surface - are an essential component of nanomaterial synthesis, processin

112 s a pivotal role in DNA metabolism and is an essential component of NER.

113 Because AEG-1 is an essential component of NF-kappaB activation, we interrog

114 Expression of hUPF2, another essential component of NMD, also improves survival, wher

115 Diverse radiochemistry is an essential component of nuclear medicine; this includes i

116 vision of quality health care and thus is an essential component of nurse education.

117 nagement of influenza virus infection and an essential component of pandemic preparedness.

118 ion of these viruses in mammals, which is an essential component of pandemic risk assessment.

119 Thus, the proteasome is an essential component of pathogen-associated molecular pat

120 Porcine circovirus 2 (PCV2) is an essential component of PCVAD, although an etiologic role

121 results show that associative learning is an essential component of plant behaviour.

122 e promyelocytic leukemia (PML) protein is an essential component of PML nuclear bodies (PML NBs) freq

123 d effective multimodal pain management is an essential component of postoperative recovery, but there

124 development (EED) is a non-catalytic but an essential component of PRC2 and its mutations were ident

125 tions using high-throughput sequencing is an essential component of precision cancer medicine.

126 An essential component of precision medicine is the ability

127 at low frequencies in clinical samples is an essential component of precision medicine.

128 e nucleoside analog cytarabine (Ara-C) is an essential component of primary and salvage chemotherapy

129 esident memory CD8+ T (CD8 TRM) cells are an essential component of protective immune responses at ba

130 Memory CD8(+) T cells are an essential component of protective immunity.

131 duces degradation of gasdermin D (GSDMD), an essential component of pyroptosis.

132 They also have a public-health role as an essential component of recent, comprehensive scale-ups o

133 T-cell immunity might be an essential component of safe, efficacious, and durable Zi

134 eat studies and obtain similar results is an essential component of science.

135 impurity doping of bulk semiconductors is an essential component of semiconductor science and technol

136 uspicion combined with diagnostic testing is essential component of severe acute respiratory infectio

137 Processing facial expressions is an essential component of social interaction, especially fo

138 s (CPRs), making these auxiliary proteins an essential component of specialized metabolism.

139 tion/deficiency in activation 3 (ADA3) is an essential component of specific histone acetyltransferas

140 belonging to the Ski2-like subfamily and an essential component of spliceosome.

141 pogenesis and favors energy production is an essential component of TGFbeta1-induced EMT and metastas

142 cells clearly demonstrate that miRNAs are an essential component of that gene regulation.

143 Complement factor B (cfB) is an essential component of the alternative pathway (AP) and

144 The basal forebrain (BF) is an essential component of the ascending arousal systems and

145 regulate autophagy by blocking Beclin 1, an essential component of the autophagy initiation complex.

146 GlcNAc) residues including peptidoglycan, an essential component of the bacterial cell wall.

147 Midbrain dopamine neurons are an essential component of the basal ganglia circuitry, play

148 avior, signals reward and novelty, and is an essential component of the basal ganglia in all vertebra

149 ng the canonical Wnt signaling pathway as an essential component of the beta-catenin destruction comp

150 ver, it remains unclear which role MALT1, an essential component of the CARD11-BCL10-MALT1 complex th

151 racterized CARBONIC ANHYDRASE 1 (CAH1) as an essential component of the CCM in N. oceanica CCMP1779.

152 RIM (tripartite motif) family protein, is an essential component of the cell membrane repair machiner

153 ious observations that the gH cytotail is an essential component of the cell-cell fusion mechanism an

154 haperone heat-shock protein 90 (Hsp90) is an essential component of the cellular homeostatic machiner

155 Regulatory T cells (Tregs) are an essential component of the cellular immune response, occ

156 potential vanilloid 1 (TRPV1) channel is an essential component of the cellular mechanism through wh

157 ning complex (EC) has been established as an essential component of the circadian clock with conserve

158 Inhibitory interneurons constitute an essential component of the circuitry and are fundamental

159 RCM-1 as the protein partner of RCO-1 and an essential component of the clock through its role in sup

160 ultisubunit protein complex, dynactin, is an essential component of the cytoplasmic dynein motor.

161 CIA1 (CIAO1), an essential component of the cytosolic iron-sulfur protein

162 riphosphate phosphohydrolase I (NPH I) is an essential component of the early gene transcription comp

163 Glycoprotein (GP), an essential component of the EBOV genome, is highly variab

164 otein (SH3 and cysteine-rich domain 3) is an essential component of the EC coupling apparatus and a m

165 CoQ10 is an essential component of the electron transport chain (ETC

166 Therefore, low O2 tension is an essential component of the epidermal environment that co

167 tream regulator of the Rb/E2F pathway, is an essential component of the ErbB2/Ras (but not the Wnt/My

168 Iron is an essential component of the erythrocyte protein hemoglobi

169 Heparan sulfate (HS) is an essential component of the extracellular matrix (ECM), w

170 We recently identified YAP as an essential component of the glomerular filtration barrier

171 The essential component of the glycan structure is the first

172 Nucleotide sugar transporters (NSTs) are an essential component of the glycosylation pathway, provid

173 ort, we identify the phosphatase PPM1B as an essential component of the Groucho4 repressor complex th

174 PTX3 is an essential component of the humoral arm of innate immunit

175 Whereas it is established that IFNAR1 is an essential component of the IFNAR signaling complex, the

176 Macrophages are an essential component of the immune response to ischaemic

177 obial effects against C. difficile and is an essential component of the innate immune response to CDI

178 As COI1 is an essential component of the JA co-receptor complex, the n

179 f 3-deoxy-D-manno-octulosonic acid (Kdo), an essential component of the lipopolysaccharide in Gram-ne

180 We showed that LepB is also an essential component of the machinery hijacked by the tRN

181 These results suggest that GlsA/ZFR is an essential component of the machinery that maintains the

182 c-specific genetic inactivation of Sin3B, an essential component of the mammalian Sin3-histone deacet

183 Detection of extracardiac lesions is an essential component of the management and outcome of IE.

184 Here we characterize ZRSR2 as an essential component of the minor spliceosome (U12 depend

185 al matrix protein cyclophilin D (CypD) is an essential component of the mitochondrial permeability tr

186 Deletion of Mpc2, which encodes an essential component of the mitochondrial pyruvate carrie

187 Our work establishes Top3alpha as an essential component of the mtDNA replication machinery a

188 Docosahexaenoic acid (DHA, 22:6n-3) is an essential component of the nervous system, and maternal

189 Fundoscopic examination is an essential component of the neurologic examination.

190 We examined mice overexpressing IKKbeta, an essential component of the NF-kappaB pathway, under kera

191 ic mutations in UPF1, a gene that encodes an essential component of the nonsense-mediated RNA decay (

192 have supported the use of vaccination as an essential component of the official FMD control programs

193 Furthermore, Hes1 is an essential component of the pancreatic intraepithelial ne

194 n J, a member of the ParB superfamily) is an essential component of the ParABS (partition system of P

195 Our results thus identify CHMP5 as an essential component of the post-translational machinery

196 ha- and beta-subunits of cytochrome b559, an essential component of the PSII reaction-center complex.

197 MERIT40 is an essential component of the RAP80 ubiquitin recognition c

198 Ribosomal protein S6 (rpS6) is an essential component of the ribosome and is inducibly pho

199 g aggregation and degradation of Nebulin, an essential component of the sarcomere.

200 The exocyst is an essential component of the secretory pathway required fo

201 Protection of Telomere 1 (POT1) is an essential component of the shelterin complex and functio

202 ineage-specific genetic ablation of TRF2, an essential component of the shelterin complex that protec

203 rylatable phosphocarrier protein (HPr) is an essential component of the sugar-transporting phosphotra

204 s-of-function mutations in SMG9, encoding an essential component of the SURF complex that generates p

205 Telomerase RNA (TER) is an essential component of the telomerase ribonucleoprotein

206 Electrostatic force is an essential component of the total force acting between at

207 sphatidylinositol anchor attachment 1) is an essential component of the transamidase complex along wi

208 zes with TAC65, a previously uncharacterized essential component of the tripartite attachment complex

209 is the human ortholog of the yeast Trm82, an essential component of the Trm8/Trm82 holoenzyme that ef

210 C virus (HCV) NS3-4A protease is not only an essential component of the viral replication complex and

211 eract with the nucleocapsid protein (NP), an essential component of the viral RNA genome complex (RNP

212 peats (LRRs) at its C-terminal end and is an essential component of the volume-regulated anion channe

213 An essential component of the wound response, JNK signaling

214 An essential component of this checkpoint is the large (151

215 ull mutation in the Bloc1s6 gene encoding an essential component of this complex.

216 authors identify the Rab GTPase Rab35 as an essential component of this contractile process, which f

217 tures of apo- and haemoglobin-bound HpuA, an essential component of this haem import system.

218 An essential component of this sigma(70)-dependent pause is

219 Iodine is an essential component of thyroid hormone.

220 t Mycobacterium tuberculosis infection is an essential component of tuberculosis control in some sett

221 Vaccine adjuvants are an essential component of vaccine design, helping to genera

222 codes for the (pro)renin receptor and is an essential component of vacuolar H+ ATPase.

223 to-microglial communication via CX3CR1 is an essential component of visual cortical development and p

224 WELL1 (LRRC8A) was recently identified as an essential component of VRAC.

225 We show that Merlin and Ezrin are essential components of a mechanism whereby mechanical f

226 Fifth, essential components of a successful program will includ

227 5 atherosclerotic lesion proteins, including essential components of adhesion complex, cytoskeleton,

228 Legumes are essential components of agricultural systems because the

229 We view these developments as essential components of an emerging 'respectful modeling

230 Here, we show that essential components of ATR signaling in murine somatic

231 the immune system, yet the glycans are also essential components of binding epitopes for numerous br

232 Phospholipids are highly conserved and essential components of biological membranes.

233 ancer risk from population-based studies are essential components of cancer risk prediction.

234 of astigmatism should not be an option, but essential components of cataract surgery.

235 ogel films used as membranes or coatings are essential components of devices interfaced with biologic

236 Divalent metal ions are essential components of DNA polymerases both for catalys

237 Sphingolipids are essential components of eukaryotic membranes, where they

238 le size calculation and power estimation are essential components of experimental designs in biomedic

239 Tree mortality, growth, and recruitment are essential components of forest dynamics and resiliency,

240 Platelets are essential components of hemostasis.

241 rse transcriptase inhibitors (NRTIs) are the essential components of highly active antiretroviral (HA

242 mmunodeficiency virus (HIV) load testing are essential components of HIV care, and making these tests

243 ng system and the superconducting magnet are essential components of magnetic resonance imaging (MRI)

244 Macrophages are essential components of mammalian tissues.

245 Iodine contrast media are essential components of many imaging procedures.

246 Broadband absorbers are essential components of many light detection, energy har

247 phingomyelin to ceramide and phosphocholine, essential components of myelin in neurons.

248 se-grained molecular model that captures the essential components of nonspecific intermolecular inter

249 rve as regulators of gene expression and are essential components of normal development as well as mo

250 ), Opn4(-/-) triple knockout (TKO) mice lack essential components of phototransduction signalling pat

251 regulators of alternative splicing (AS) are essential components of posttranscriptional gene regulat

252 d three major MAPKs (P38, ERK, and JNK), the essential components of signaling pathways downstream of

253 ve and respond to environmental stimuli, are essential components of smart textiles.

254 stone H3 variant Cse4 and its homologues are essential components of specialized centromere (CEN)-spe

255 Hrd1 and ERAD are essential components of the adaptive ER stress response

256 cognition Motif-containing (ORRM) family are essential components of the Arabidopsis (Arabidopsis tha

257 Remarkably, many essential components of the beta cell transcriptional ne

258 coding and directionally sensitive cells are essential components of the brain circuitry mediating in

259 Tumor-associated macrophages (TAMs) are essential components of the cancer microenvironment and

260 otein 1) have been recently characterized as essential components of the chloroplast RNA editing appa

261 synthesizing 13 membrane proteins that form essential components of the complexes involved in oxidat

262 All essential components of the device like the light source

263 protein from Escherichia coli is one of the essential components of the division proto-ring that pro

264 These data suggest that SPAK and OSR1 are essential components of the effector pathway that mainta

265 e-stranded RNAs targeting ku70 or lig4, both essential components of the end-joining response, increa

266 As essential components of the eukaryotic cytoskeleton, mic

267 They are essential components of the fat body, a metabolic tissue

268 Interferons (IFNs) are essential components of the host innate immune system an

269 have potent antimicrobial properties and are essential components of the immune response to invading

270 Nucleic acid editing enzymes are essential components of the immune system that lethally

271 Macrophages are essential components of the inflammatory microenvironmen

272 Essential components of the innate immune antiviral resp

273 d for the isolation of carp serum, which are essential components of the medium required to grow zebr

274 an transcription factors CLOCK and BMAL1 are essential components of the molecular clock that coordin

275 atic analyses, we found that homologs of the essential components of the Mu baseplate can be identifi

276 The cytokine IL-22 and inflammasomes are essential components of the mucosal responses to C. albi

277 Mycolic acids are essential components of the mycobacterial cell envelope,

278 Mycolic acids are essential components of the mycobacterial cell envelope,

279 Glial cells are essential components of the nervous system.

280 Nucleoporins are essential components of the nuclear pore complex (NPC).

281 Histones are essential components of the nucleosome, the major chroma

282 unction tetraspan membrane proteins that are essential components of the paracellular barrier.

283 ent of antimicrobial stewardship programs as essential components of the present and future healthcar

284 of proteinuric kidney disease.Podocytes are essential components of the renal glomerular filtration

285 at FMRP inhibits translation by blocking the essential components of the translational machinery from

286 f muramic acid residues in peptidoglycan are essential components of the varphi11 receptor.

287 of how other Gram-positive bacteria produce essential components of their cell wall.

288 ger to release Ca(2+) on their own appear as essential components of this arrhythmogenic scheme.

289 Two essential components of this switch, miR-200 and miR-155

290 C3, which have previously been identified as essential components of transmitting tract formation, af

291 pointed to thioredoxin reductase (TrxR), an essential component required for BoNT protease transloca

292 s both as a uracil-DNA glycosylase and as an essential component required for processive DNA synthesi

293 We find that Drosophila Neto functions as an essential component required for the function of NMJ glu

294 xible and wearable human vitals sensors, the essential components required for vitals sensors are out

295 he cytosolic complexes, possibly through the essential component SctK/YscK, revealing a potential mec

296 ell cycle checkpoints, as well as on related essential components, such as CDK1, CDK2, cell size, and

297 ermined, or the climate models still lack an essential component that would serve to elevate surface

298 nery of heart and skeletal muscles has as an essential component the thick filament, comprised of the

299 emory, and is accompanied by confusion as an essential component; this should be suspected from the i

300 ng customer acceptance and secondly they are essential components with positive health effects either