ライフサイエンスコーパス: essential tremor

1 ultrasound thalamotomy for the treatment of essential tremor.

2 s: Parkinson's disease, primary dystonia and essential tremor.

3 tructural abnormalities in the brain such as essential tremor.

4 overdiagnosis of well-known causes, such as essential tremor.

5 ceptor antagonist, can trigger or exacerbate essential tremor.

6 and potential targets for pharmacotherapy of essential tremor.

7 nt findings of mild olfactory dysfunction in essential tremor.

8 innervation, as did the member with isolated essential tremor.

9 most common causes are Parkinson disease and essential tremor.

10 the primary motor cortex in individuals with essential tremor.

11 thmic motor drive responsible for generating essential tremor.

12 suffer from postural tremor, consistent with essential tremor.

13 include Lewy body dementia and some forms of essential tremor.

14 ng tremor, but not in Parkinson's disease or essential tremor.

15 were significantly improved in patients with essential tremor.

16 reatest alpha desynchronization occurring in essential tremor.

17 history studies show a high heritability for essential tremor.

18 al coactivator PPARGC1A were associated with essential tremor.

19 LINGO1) did not confirm the association with essential tremor.

20 safety and efficacy of DBS in patients with essential tremor.

21 ould be of importance in the pathogenesis of essential tremor.

22 s with the degree of clinical improvement in essential tremor.

23 c acid tone seems to be a central feature of essential tremor.

24 ing an important role in the pathogenesis of essential tremor.

25 in stimulation pulses are delivered to treat essential tremor.

26 n of the thalamus can help ameliorate severe essential tremor.

27 s in the Purkinje cell axonal compartment in essential tremor.

28 h clinical diagnostic error rates for PD and essential tremor.

29 patients with severe, medication-refractory essential tremor.

30 ges and cell death deserves further study in essential tremor.

31 ring stereotactic surgery for the control of essential tremor (70 patients).

32 conducted a genome-wide association study of essential tremor, a common movement disorder characteriz

33 on's disease, obsessive-compulsive disorder, essential tremor, addiction, pain, minimally conscious s

34 m, one clinically normal and one with benign essential tremor alone.

35 nucleus of the thalamus in 29 patients with essential tremor and 24 patients with Parkinson's diseas

36 erebellar cortical tissue from 27 cases with essential tremor and 27 age-matched control subjects was

37 f the Purkinje cell axonal compartment in 49 essential tremor and 39 control brains, using calbindin

38 ebellar syndrome (multiple sclerosis, n = 3; essential tremor and ataxia, n = 1), although clinical t

39 h Parkinson's disease, in four subjects with essential tremor and in none of the subjects with psycho

40 ations for understanding the pathogenesis of essential tremor and its relationship to Parkinson disea

41 This review will consider Parkinson disease, essential tremor and other tremors and highlight advance

42 en Food and Drug Administration-approved for essential tremor and Parkinson disease and has a humanit

43 Common tremors like essential tremor and Parkinson disease tremor can be rec

44 based management of the most common tremors, essential tremor and Parkinson disease tremor.

45 ion consanguineous Turkish kindred with both essential tremor and Parkinson disease, we carried out w

46 lso showed good efficacy in rodent models of essential tremor and Parkinson's disease.

47 cal therapy for movement disorders including essential tremor and Parkinson's disease.

48 phy to discriminate Parkinson's disease from essential tremor and Parkinsonism, the involvement of no

49 rentiating parkinsonian syndromes (PS), from essential tremor and probable dementia with Lewy bodies

50 Accordingly, we stimulated 10 patients with essential tremor and thalamic electrodes, while recordin

51 HTRA2 p.G399S is responsible for hereditary essential tremor and that homozygotes for this allele de

52 Pharmacologic treatment for essential tremor and the tremor of Parkinson's disease i

53 the tapping limb in Parkinson's disease and essential tremor, and its frequency in many cases shifte

54 nts than Parkinson's disease rest tremor and essential tremor, and its frequency was less consistent.

55 uggest an association between blood lead and essential tremor, and that this association is modified

56 disease and 20 postural tremor recordings in essential tremor, and validated on a second, independent

57 neuronal and EMG activities during intention essential tremor are similar to those of the intention t

58 The molecular genetic determinants of essential tremor are unknown.

59 orrelates of clinical heterogeneity in human essential tremor are unknown.

60 n the efficacy of neurosurgical treatment of essential tremor, are in contrast to those of previous s

61 siology of other movement disorders, such as essential tremor, are relatively unexplored.

62 Here, I show that observations on essential tremor arising from clinical practice/clinical

63 ern regarding the potential risks of certain essential tremors associated with the long-term, low-lev

64 a safe and effective therapy for refractory essential tremor, but information regarding long-term ou

65 y of focused ultrasound (FUS) thalamotomy in essential tremor, but its effectiveness and safety for m

66 otor cortex were made from six patients with essential tremor by magnetoencephalography.

67 t that subjects with Parkinson's disease and essential tremor can produce movements that are kinemati

68 , the dendritic spine density was reduced in essential tremor cases (medians=0.82 versus 1.02 microm(

69 climbing fibre-Purkinje cell synapses of 12 essential tremor cases and 13 age-matched controls from

70 apses using post-mortem cerebellar tissue of essential tremor cases and controls.

71 In all measures, essential tremor cases demonstrated significant reductio

72 We observed that, compared with controls, essential tremor cases had decreased climbing fibre-Purk

73 orpedoes) are present to a greater degree in essential tremor cases than controls.

74 apparent in the Purkinje cell population in essential tremor cases versus age-matched controls.

75 Median values in essential tremor cases versus controls were: 5712.1 vers

76 ] were all present to an increased degree in essential tremor cases versus controls.

77 d were correlated with tremor duration among essential tremor cases with age of onset >40 years.

78 In essential tremor cases, thickened axonal profiles, axona

79 We examined autopsy tissue from the Essential Tremor Centralized Brain Repository.

80 n Purkinje cells have been identified in the essential tremor cerebellum, although the mechanisms tha

81 logical differences between parkinsonian and essential tremor circuits.

82 remor suppression) in selected patients with essential tremor despite delivering less than half the e

83 Some but not all persons with essential tremor develop signs of Parkinson disease, and

84 tor incoordination that is characteristic of essential tremor disease.

85 ulation surgery, compared with patients with essential tremor (ET) and isolated dystonia (ID).

86 ical disorders, neuropathological studies of essential tremor (ET) are rare.

87 Parkinson's disease (PD) and essential tremor (ET) are the two most common movement d

88 Thalamomuscular coherence in essential tremor (ET) has consistently been detected in

89 Essential tremor (ET) is a common condition that is pres

90 Essential tremor (ET) is a common movement disorder with

91 Essential tremor (ET) is among the most misdiagnosed neu

92 Essential tremor (ET) is one of the most common neurolog

93 Essential tremor (ET) is one of the most common neurolog

94 Essential tremor (ET) is one of the most prevalent movem

95 Essential tremor (ET) is the most prevalent adult-onset

96 Essential tremor (ET) is the most prevalent movement dis

97 ese patients with that seen in patients with essential tremor (ET) using two neurophysiological techn

98 Essential tremor (ET), a movement disorder characterised

99 The causative genes for essential tremor (ET), one of the most common genetic ne

100 Essential tremor (ET), the cause of which remains poorly

101 The pathophysiology of essential tremor (ET), the most common movement disorder

102 n to have efficacy in treating patients with essential tremor (ET).

103 cted white matter microstructural changes in essential tremor (ET).

104 safe and effective therapy in patients with essential tremor followed for up to 13 years.

105 Patients treated with DBS for essential tremor for at least 8 years were evaluated in

106 ced by low frequency thalamic stimulation in essential tremor has a narrower frequency-amplitude tole

107 termedius nucleus deep brain stimulation for essential tremor has been the loss of surgical efficacy

108 In this pilot study, essential tremor improved in 15 patients treated with MR

109 rformance for Parkinson's disease tremor and essential tremor, in both test and validation datasets.

110 rders including Parkinson's disease (PD) and essential tremor is determined through clinical assessme

111 Essential tremor is one of the most frequent movement di

112 Essential tremor is the most common movement disorder an

113 Clinically Parkinson disease and essential tremor may be confused with each other but it

114 ease of the cerebellum or cerebellar system; essential tremor may be neurodegenerative; low gamma ami

115 hat the effects of electrical stimulation on essential tremor may be phase dependent, and that, in pa

116 These include the following: essential tremor may represent a family of diseases rath

117 , only ventrolateral thalamic stimulation in essential tremor modulated postural tremor amplitude acc

118 c to Parkinson's disease, but also occurs in essential tremor, most prominently for the coupling of a

119 subjects with Parkinson's disease (n = 20), essential tremor (n = 8) and psychogenic tremor (n = 7).

120 ects with Parkinson's disease (n = 11), with essential tremor (n = 9) and without a movement disorder

121 nts had a history of either isolated tremor (essential tremor, n = 2; benign tremulous Parkinson's di

122 urodegeneration such as Alzheimer's disease, essential tremor or drug-induced parkinsonism and hence

123 dramatically relieve tremor associated with essential tremor or Parkinson disease (PD).

124 S surgeries in 25 human patients with either essential tremor or Parkinson's disease, we acutely reco

125 .0312; ventrolateral thalamic stimulation in essential tremor, P=0.0137; two-tailed paired Wilcoxon s

126 nt drug therapies that alleviate symptoms in essential tremor patients (primidone, propranolol, and g

127 h a clinical diagnosis of PS, non-PS (mainly essential tremor), probable DLB, and non-DLB (mainly Alz

128 eatment efficacy with the Quality of Life in Essential Tremor Questionnaire (ranging from 0 to 100%,

129 further 55 tremulous Parkinson's disease and essential tremor recordings.

130 je cell dendritic architecture and spines in essential tremor relative to control brains provides add

131 Recent essential tremor research has given rise to several nove

132 ly of diseases rather than a single disease; essential tremor seems to be a disease of the cerebellum

133 arkinson's disease and in all four remaining essential tremor subjects but in none of the psychogenic

134 ter in subjects with Parkinson's disease and essential tremor than in subjects without a movement dis

135 Kinetic tremor may be more prominent in essential tremor than postural tremor.

136 mbles other common tremor disorders (such as essential tremor) that occur in patients who have an oth

137 ogram at tremor frequencies suggests that in essential tremor the tremor is imposed on the active mus

138 Interestingly, in essential tremor, the increased distribution of climbing

139 cardinal feature of Parkinson's disease and essential tremor, the two most common movement disorders

140 ow of ideas from clinical observations about essential tremor, to their translation into scientific s

141 e ventralis intermedius thalamic nucleus for essential tremor underwent functional magnetic resonance

142 Essential tremor was present in persons either heterozyg

143 of abnormalities in Purkinje cell biology in essential tremor, we hypothesized that regressive change

144 These types of essential tremor were compared with patients having inte

145 Nine patients with essential tremor were divided clinically into two catego

146 sent, 15 patients with medication-refractory essential tremor were enrolled in a HIPAA-compliant pilo

147 variability of SCN4A with the development of essential tremor, which adds ET to the growing list of n

148 Such differences in parkinsonian rest and essential tremor will be important in selecting future s

149 discriminate Parkinson's disease tremor and essential tremor with high diagnostic accuracy.

150 ents, age: 50-77 years) and 10 patients with essential tremor with thalamic electrodes (nine male and

151 tnessed a remarkable increase in research on essential tremor, with consequent advances in our unders

152 cortical activity in Parkinson's disease and essential tremor, with the greatest high-beta desynchron