1 These results
establish that (
1) plastidial AtCPT7 extends the length
2 Pharmacokinetic studies
established that 13-d had properties compatible with ora
3 We have also
established that 2-AG levels are upregulated in the seru
4 Previous studies have
established that 2-alkylcyclobutanones (2-ACBs) are uniq
5 Protein X-ray crystallography
established that 3-unsubstituted 2,4-oxazolidinediones b
6 Together, our findings
establish that a 6-12 Hz theta rhythm, generated by the
7 In this investigation, we
establish that a chiral nickel catalyst can mediate doub
8 Here we
establish that a genetic network controlling the phospha
9 Further evidence may be required to
establish that a mixed catheter package is equivalent to
10 We
establish that a predicted heme-molybdenum cofactor-cont
11 Thus, our results
establish that a region within area 5 contains a motor a
12 We
established that a chloroplast transcriptional response
13 stane Study and contemporaneous studies have
established that a strategy of switching to an aromatase
14 Although it is
established that ABC half-transporters have at least to
15 with single-guide RNA-bound SpyCas9, thereby
establishing that AcrIIA4 preferentially targets critica
16 Taken together, these results
establish that activation of the CBS/H2S axis promotes c
17 Studies have
established that advanced age, male sex, and European an
18 It is now
established that adverse conditions during pregnancy can
19 These results
establish that aldolase, as well as being a glycolytic e
20 and palaeomagnetic analyses of flowstones to
establish that all sediments containing Homo naledi foss
21 It is well
established that all seven serotypes of BoNTs (BoNT/A-G)
22 These findings firmly
establish that alterations in innate immunity influence
23 Here, we
establish that although ICP34.5 binds TBK1 under certain
24 Our results
establish that,
although gamma-2 is not typically associ
25 We also
establish that an ABC transporter of unknown function, Y
26 These data
establish that an inactivated RABV-MERS S-based vaccine
27 We previously
established that an insulin-like growth factor 1 (IGF-1)
28 Furthermore, we have
established that ANG-ALS variants which affect the struc
29 It is well
established that anthropogenic chlorine-containing chemi
30 We previously
established that antibodies are essential for rVSV-EBOV
31 The present study further
establishes that any of the three double-ring building b
32 It is well
established that,
apart from its distinct role in blood
33 In conclusion, our results
establish that APLPs show typical features of SAMs and i
34 This study has
established that,
as in schizophrenia, there is a therap
35 on and in vivo analysis of INM targeting, we
establish that Atlastins, membrane-bound GTPases of the
36 and other findings in our study conclusively
establish that ATM activity poses a major barrier to onc
37 By using chromosome breakpoint data, we
established that avian interchromosomal breakpoints appe
38 nd water filtrate from the surrounding ditch
established that bacteria of A. filiculoides differed en
39 It is now
established that Bcl11b specifies T cell fate.
40 It has previously been
established that behavioural variant frontotemporal deme
41 mum Likelihood Structural Equation Modelling
established that beverage preferences have a moderate to
42 and co-immunoprecipitation-based assays, we
establish that binding at either site increases affinity
43 This chronological arc
establishes that bison first entered North America durin
44 naling concurrent with PASE development, and
establish that BMP-SMAD activation/inhibition modulates
45 We further
establish that BONCAT can be coupled to tandem liquid ch
46 Twin studies have
established that both genes and environment play importa
47 Our study
establishes that both quantum interference and heteroaro
48 While it is well
established that broad-scale patterns of abiotic and bio
49 While this value
establishes that C-C cleavage is part of the rate-determ
50 Altogether, our data clearly
establish that Ca(2+) entry exerts a feedback control on
51 atic people, a Babesia carriage state can be
established that can last up to a year or more.
52 It is well
established that canonical eukaryotic pre-mRNA 3' proces
53 It is well
established that cardiorespiratory fitness (CRF) is inve
54 Our data
establish that cargoes containing Yxxphi motif, but not
55 of demyelination and mice of either sex, we
establish that Cav1.2 deletion in OPCs leads to less eff
56 ) OPCs were identified by a Cre reporter, we
establish that Cav1.2(KO) OPCs display a reduced maturat
57 Further, magnetic studies have
established that Ce3Mn8 exhibits both the combination of
58 tions in animals and post-mortem humans have
established that cerebro-cerebellar connections are cont
59 Multiple studies have
established that certain inflammatory disorders and infl
60 brain tumor patients to healthy children, we
establish that changes in the microstructure of the opti
61 These findings
establish that cholesterol plays a critical role in modu
62 Over the last decades, it has been
established that chronic antigen stimulation during pers
63 disease is poorly understood, although it is
established that circulating pathogenic natural IgM, whi
64 While it is well
established that climbing fibre signals are important fo
65 These findings
establish that clinical resistance to quizartinib is hig
66 This study
establishes that CMV protein pUL31 is necessary and suff
67 We
established that competition between cytokine diffusion
68 These data definitively
establish that complete structural integrity is necessar
69 These data
establish that compound 23 (BETd-260/ZBC260) is a highly
70 Further biochemical studies
establish that coordination of Ni(II) at the hexahistidi
71 ever, using deuterated POPC we could clearly
establish that COR15A interacts with the membranes and p
72 Many in vitro studies have
established that crystallin proteins precipitate into ag
73 We also
established that CTL1 is involved in regulating vesicle
74 Most significantly, we
established that CYGB increased the expression of NFsmal
75 It is now well
established that data from FFQs and other self-reported
76 Analysis of Mov10l1(-/-) testes
established that de novo methylation of the L1 transgene
77 Our findings
establish that defective MRM2 causes a MELAS-like phenot
78 Consequently, this study
establishes that DeltaS is proportional to S0 and that t
79 For many years, it has been
established that deregulated expression of transcription
80 We have previously
established that despite the apparent surface uniformity
81 Taken together, our findings
establish that differential expression of several MAPK f
82 Preliminary work in AD has
established that disease-associated T-cell abnormalities
83 We further
establish that DNA demethylation induced by XPC expressi
84 Previous investigations have
established that DnaB is composed of an N-terminal domai
85 Here we
establish that DOCK5 has a non-redundant role in regulat
86 These studies
establish that donor age is associated with an increased
87 the Kir2.1(+/-) heterozygous mouse model, we
establish that downregulation of Kir2.1 results in signi
88 These results
establish that driver gene mutations are associated with
89 It was recently
established that electrospray ionization mass spectromet
90 of this disease remains unknown, it is well
established that endometriosis patients exhibit immune d
91 It is now
established that epilepsy is characterized by periodic d
92 Taken together, our findings
establish that EVs secreted by AFSC could target a speci
93 zed by an exchange rate [Formula: see text],
establishing that FD of Fis occurs at the single-binding
94 Collectively, these studies
establish that female gonadal sex hormones underlie the
95 It is
established that FHL can operate as a highly efficient h
96 This work
establishes that Fhod shares the capacity of other formi
97 We further
established that FI-HSV-2 alone or in combination with a
98 Thus, our findings
establish that fibrotic lung disease is mediated, in par
99 It was
established that,
for thermo-oxidative degradation, Pois
100 g an FRS2,3-binding site mutant of Fgfr1, we
established that FRS adapters are necessary for mediatin
101 Although it is now well
established that gammadelta T cells can be rapidly recru
102 r samples, we confirmed this association and
established that germline nonsense and frameshift varian
103 It is well
established that glutamate and GABA signal through both
104 Our results
establish that Grc3 drives Las1 endoribonuclease cleavag
105 It is
established that H. pylori stimulates neutrophil chemota
106 histone acetylase and deacetylase activities
established that histone acetylation marks are necessary
107 However, we recently
established that HIV-1 can infect kidney transplant epit
108 These findings
establish that holo-RBP and its receptor STRA6 are poten
109 We further used AD-iN cells to
establish that human collybistin, the loss of gene funct
110 t none of the experiments they review really
establishes that human adults, infants, or nonhuman anim
111 Whereas it is
established that IFNAR1 is an essential component of the
112 Overall, our results
establish that Igf2 LOI is sufficient on its own to incr
113 Previous work in rodents has
established that immune activation during critical devel
114 These results firmly
establish that in HIV-1, CA is a strong determinant of s
115 We have recently
established that in Arabidopsis, the regulator of G-prot
116 ic factors.SIGNIFICANCE STATEMENT This study
establishes that in neurogenic niches of an adult diurna
117 Although it is well
established that Influenza A virus infection is initiate
118 Using chemical inhibitors, we
established that inhibition of p38, but not ERK or JNK,
119 These studies have
established that,
instead of simply balancing excitatory
120 section with single cell transcriptomics, we
establish that interferon-stimulated gene expression is
121 These findings
establish that IP6K1 physiologically regulates neuronal
122 Furthermore, we
establish that IR25a and IR76b are essential in sour GRN
123 motility, a leading-lagging cell polarity is
established that is inverted during cellular reversals.
124 This study
establishes that ISG15 itself restricts HCMV replication
125 Moreover, it
establishes that ISGylation modifies the proteomes of vi
126 This study
establishes that IUGR also leads to impairment of the ri
127 Our results
establish that KLF10 functions to suppress TGFbeta-induc
128 Using a mitochondrial fusion assay, we
established that L-OPA1 confers fusion competence, where
129 Using real-time single-molecule analysis, we
establish that leading- and lagging-strand DNA polymeras
130 ses and a 1.9 A resolution crystal structure
established that LigY belongs to the amidohydrolase supe
131 Previous work
established that Lis1, a conserved regulator of dynein,
132 We
established that loss of miR-874-mediated control of cyc
133 analyses of miR-383 in PCa clinical tissues
established that low miR-383 expression is associated wi
134 Using time-resolved spectroscopy, we
establish that luminescence via triplets occurs within 3
135 These results clearly
establish that MCs may contribute to host defences to Le
136 ndencies for competing modes of disrotation,
establishing that meaningful changes in dynamically cont
137 g of mechano-insensitive formin mutant cells
established that mechanoregulation of formin Cdc12 is re
138 We have previously
established that methylerythritol cyclodiphosphate (MEcP
139 Although it is well
established that methylphenidate (MPH) enhances sustaine
140 These data
establish that Miro1-mediated mitochondrial positioning
141 In macrophages, previous studies have
established that mitogen- and stress-activated protein k
142 These results
establish that ML function is crucial for detection of f
143 Our work
establishes that MLIs in the lateral cerebellum are broa
144 These results
establish that mo-DCs and mo-Macs are controlled by dist
145 We
establish that monomeric BslA is necessary and sufficien
146 dex of Heart Attack Risk in College Alumni",
established that more strenuous PA reduced the risk of h
147 We
established that more than seven galacturonic acid resid
148 To this end, we first
established that MRgFUS is capable of significantly enha
149 Our data
establish that MRPS34 is required for normal function of
150 e its contribution at 25 degrees C, our work
establishes that Myo2p is the major motor involved in ri
151 Recent studies
established that nascent autophagosomes in distal axons
152 Ancient DNA studies have
established that Neolithic European populations were des
153 Together, our findings
establish that Nep1 and dAbeta expressed in DPM neurons
154 It is well
established that networks within multiple-demand cortex
155 These findings
establish that neuronal transcriptomic identity correspo
156 More recently, it has been
established that NMDAR-mediated transmission can be dyna
157 Collectively, these experiments
establish that not all phagocytic receptors are function
158 Microbiome-wide association studies have
established that numerous diseases are associated with c
159 We
established that oligosaccharide stannanes could be prep
160 The findings
establish that OMCCs are highly structurally and functio
161 We
establish that,
on timescales relevant to epithelial mor
162 lding or translocation is rate limiting, and
establish that one or a few power strokes are sufficient
163 em cell function in vitro as well as in vivo
established that only HSCs and not investigated progenit
164 posited as fibrils in the patient's kidneys,
establishing that only a small portion of Phe521Leufs di
165 These findings
establish that oocytes generated during adulthood contri
166 cted by a micron-scale magnetic dipole, thus
establishing that our sorter can be an instrument for na
167 T-cells from WT and OX40(-/-) mice we first
established that OX40 mediated activation of NF-kB was c
168 atients approaching the end of life and well-
established that patients and carers hold fears relating
169 chanistic, and in situ spectroscopic studies
establish that Pd(II)-mediated C-H activation is the tur
170 Although it is well
established that PD-1-PD-L1 blockade activates T cells,
171 Our findings
establish that pericytes promote endothelial sprouting,
172 These studies
establish that peripheral markers of FGF2 concentrations
173 While it is well
established that plants associating with arbuscular myco
174 It is now well
established that Polmu is the one adapted to repair DSBs
175 Many studies have
established that populations can evolve a reduced mutati
176 Using an IRES-dependent reporter system, we
established that PRMT5 facilitates the translation of a
177 In recent years, it has been
established that programmed cell death protein ligand 1
178 retical and experimental studies have firmly
established that protein folding can be described by a f
179 analyses using PTHrP1-17-specific antibodies
establish that PTHrP1-17 is indeed generated by cancer c
180 These findings
establish that PXR signaling contributes to ALD developm
181 We previously
established that Rac1 signals via Scar/WAVE and Arp2/3 t
182 In this study, we
establish that RAGE-PR3 interaction mediates homing of p
183 ses of promoter open complex (RPo) formation
establish that RbpA and CarD cooperatively stimulate for
184 These data
establish that recurrent and hierarchical connectivity b
185 endent COS/H2S release from each donor core,
establish that release profiles can be modified by struc
186 It is well
established that resource quantity and elemental stoichi
187 Here, we
establish that reversed replication forks are a patholog
188 Mechanistic studies in this setting
established that RHAMM stabilized F-actin polymerization
189 g pocket conferred resistance to rigosertib,
establishing that rigosertib kills cancer cells by desta
190 PRIMERS III
establishes that RMDs can discriminate between carbapene
191 We
establish that RNF169 binds to ubiquitylated H2A-Lys13/L
192 These results
establish that RTF2 removal is a key determinant for the
193 Here, we
establish that S-nitrosoglutathione reductase (GSNOR), a
194 Photolabeling studies
established that S-mTFD-MPPB binds to the same GABAAR in
195 by polyketide synthetase (pks) coding genes
established that seaweed-affiliated bacterial flora had
196 It is well
established that sensory afferents innervating muscle ar
197 (NOS) enzymes, research in recent years has
established that significant NO can be derived from diet
198 teracts with Mediator subunit 25 (MED25), we
establish that similar, aromatic-rich motifs located bot
199 Our studies
establish that single-base bulges 7T8, 5A6 and 4A5 on th
200 Taken together, our results
establish that SlRd2, a tomato UspA, is, to our knowledg
201 Together, these observations
establish that small molecules that bind to the interfac
202 We
establish that SNX5 and SNX6 associate with the CI-MPR t
203 s of patients with HCV infection, we did not
establish that sofosbuvir-velpatasvir-voxilaprevir for 8
204 It is well
established that somatic genomic changes can influence p
205 cute injury, and using this in vivo model we
establish that SPAR downregulation enables efficient act
206 We
establish that species of Streptomyces secrete dodecanoi
207 Although it is well
established that spoken word recognition engages the sup
208 By gain- and loss-of-function studies, we
establish that SRC stimulates the secretion of exosomes
209 Whilst it is well
established that statistical and economic considerations
210 inactive (b) conformer with even longer DAD,
establishing that stochastic conformational sampling is
211 em.SIGNIFICANCE STATEMENT Prior studies have
established that substantia nigra pars compacta (SNc) do
212 We
establish that substantial changes in vegetation and fir
213 Previous work has
established that such differences in song within a speci
214 Reciprocal transplants
established that survival benefits of GSNOR deletion wer
215 Although it is
established that synaptotagmin cannot rescue the otoferl
216 In this context, we
establish that telomerase binding to reversed replicatio
217 Mechanistically, we
established that TGFbeta is required for D-ECM productio
218 alization and in vitro functional assays, we
establish that the "neuron-specific" K(+)Cl(-) co-transp
219 These results
establish that the acquisition of model-based informatio
220 Here, we describe three examples to
establish that the approach is simple and generalizable.
221 We
establish that the domain wall state decomposes into two
222 Steady-state kinetic studies
establish that the enzyme is capable of catalysing imine
223 irescens for performance on P. angulata, and
establish that the genetic architecture of intraspecific
224 Taken together, our results
establish that the HAT activity of MOF is required to su
225 Our data
establish that the histone-based mechanism of DNA compac
226 Here, we
establish that the HSV-1 Us3 protein kinase subverts the
227 Our results
establish that the intrinsic probability of a gate enter
228 Here, we
establish that the ISG15 gene product itself directly re
229 Together, these findings
establish that the LigC complex is directly involved in
230 myosin-5 to microtubule-dependent motors, we
establish that the minus end-directed transport of SVs r
231 nctional theory-based transport calculations
establish that the new contacts dramatically increase th
232 by employing super resolution microscopy, we
establish that the ParF DNA partition protein of the Par
233 We
establish that the PhoP-activated protein MgtC protects
234 These data
establish that the PPKs are directly involved in catalys
235 We
establish that the presence of either D2L or D2S can sup
236 These data
establish that the RP-MDM2-p53 pathway, in contrast to t
237 cAMP and PKA activity in intact cells and we
establish that the sensitivity of PKA to cAMP is almost
238 lity, sensory features, and time constraints
establish that the signal reflects an active, feature- a
239 We
establish that the synaptic modulator reelin (RELN) is a
240 Now, Boulay et al.
establish that the translocated prion-like domain of the
241 Our data
establish that the vascular adventitia contains phenotyp
242 pentanoate methyl esters (8) by chiral GC-MS
established that the BonMT2-catalyzed methylation genera
243 osynthase (KS)-ketoreductase (KR) assay that
established that the decarboxylative condensation of met
244 A baseline condition
established that the demonstrated tower design was beyon
245 4 ion images with immunohistochemical images
established that the drug was taken up by macrophages as
246 The last decade
established that the dynamic properties of the phosphopr
247 In clinical specimens of breast cancer, we
established that the expression of CD44s and HAS2 was po
248 number of motile and immotile cilia, we now
established that the final number of motile cilia depend
249 confirmed by single-crystal XRD analysis, we
established that the ground state UV-vis absorption of 7
250 Although it is now well
established that the hippocampus supports memory encodin
251 Although it is
established that the host's epigenetic machinery is sens
252 Additional studies
established that the increased toxicity upon mutating Ub
253 It has been well-
established that the known TMs can be classified by the
254 eling, and (1)H and (13)C NMR techniques, we
established that the major product, MftA*, is a tyramine
255 m(-1) s(-1) at pH 7.4 and 25 degrees C), we
established that the measured decay of the intrinsic PDI
256 Although it is well
established that the number of menstrual cycles and preg
257 ron diffraction experiments at 97 and 75% RH
established that the presence of COR15A had no significa
258 ies inexorably age, a number of observations
established that the rate of aging is modulated in respo
259 A competition experiment
established that the reaction involves formation of free
260 However, although it is well
established that the receptive field surround is stronge
261 orbital innervation in mice lacking Mafb has
established that the stereotypical misinnervation of the
262 The new evidence firmly
establishes that the Al-Cu-Fe alloys (including quasicry
263 This work
establishes that the self-assembly of ferritin-MOFs is h
264 This
establishes that the Us3 kinase not only activated mTORC
265 Using the Eyring equation, we
established that their activation entropy for rotation i
266 We
establish that these CRISPR-Cas systems can achieve RNA
267 Moreover, we
establish that these eGFP(+) cells emerge from a hemogen
268 strations in three-species model systems, we
establish that these metrics capture complimentary aspec
269 We
establish that these microbial consortia act as cartels,
270 Native mass spectrometry
established that these macromolecular assemblies incorpo
271 It is well
established that these responses are also associated wit
272 Recently, we
established that these two sodium transport proteins fun
273 defective for interaction with FtsZ, it was
established that these ZapA structures form without a co
274 V/vis, CD, and (1)H NMR spectroscopy, it was
established that they still function properly as unidire
275 Moreover, we
establish that this decision is made deterministically,
276 ng a conditional knockdown strategy, we here
establish that this kinase is critical for the invasion
277 The use of A2aR-deficient CD4 T cells
established that this CGS effect was T cell intrinsic.
278 ents with two hydrophobic fluorescent probes
established that this polysaccharide complexes hydrophob
279 It has been
established that this process involves multi-step electr
280 were 97.3%, 93.9%, and 96.9%, respectively,
establishing that this method is capable of reliably pre
281 Using this method, we
established that three key neural markers accounted for
282 rlying mechanism mediating these effects and
establish that TLR4 inhibition in the PAG of females rev
283 We further
establish that TNFalpha induces IR in cardiomyocytes.
284 Here, we
establish that Toll/NF-kappaB pathway activation in the
285 Here we
establish that Toxoplasma gondii aspartyl protease 3 (AS
286 Traction force microscopy (TFM) was used to
establish that traction stresses are limited primarily t
287 Functionally, we
established that Trx1 protects GC1 from S-nitrosocystein
288 d on amorphous SiO2 as a typical example, we
establish that twin defects can be rationally generated
289 ting its utility as a discovery pipeline, we
establish that two of these proteins promote ubiquitin-l
290 Previous studies have
established that two molecules of LarE catalyze successi
291 ds, and cDNA sequencing and a splicing assay
established that two mutations, including a recurrent si
292 Our findings
establish that type I IFN-dependent responses, arising f
293 Finally, we
established that UbFluor can quantify activation or inhi
294 rent: our experimental and modelling results
establish that,
under these conditions, the ionization o
295 Our data clearly
establish that vascular CXCR4 limits atherosclerosis by
296 Previous research has
established that vehicles directly emit primary aerosol
297 It is well
established that viral pathogens exploit PD to spread be
298 We
established that WarA binds to cyclic-di-GMP, which pote
299 n oscillator containing only DNA components,
establishing that Watson-Crick base-pairing interactions
300 Low-temperature (13)C NMR spectra
established that (
Z)-1 was dissolved as a trisolvated mo