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1                                These results establish that (1) plastidial AtCPT7 extends the length
2                      Pharmacokinetic studies established that 13-d had properties compatible with ora
3                                 We have also established that 2-AG levels are upregulated in the seru
4                        Previous studies have established that 2-alkylcyclobutanones (2-ACBs) are uniq
5                Protein X-ray crystallography established that 3-unsubstituted 2,4-oxazolidinediones b
6                       Together, our findings establish that a 6-12 Hz theta rhythm, generated by the
7                    In this investigation, we establish that a chiral nickel catalyst can mediate doub
8                                      Here we establish that a genetic network controlling the phospha
9          Further evidence may be required to establish that a mixed catheter package is equivalent to
10                                           We establish that a predicted heme-molybdenum cofactor-cont
11                            Thus, our results establish that a region within area 5 contains a motor a
12                                           We established that a chloroplast transcriptional response
13 stane Study and contemporaneous studies have established that a strategy of switching to an aromatase
14                               Although it is established that ABC half-transporters have at least to
15 with single-guide RNA-bound SpyCas9, thereby establishing that AcrIIA4 preferentially targets critica
16                Taken together, these results establish that activation of the CBS/H2S axis promotes c
17                                 Studies have established that advanced age, male sex, and European an
18                                    It is now established that adverse conditions during pregnancy can
19                                These results establish that aldolase, as well as being a glycolytic e
20 and palaeomagnetic analyses of flowstones to establish that all sediments containing Homo naledi foss
21                                   It is well established that all seven serotypes of BoNTs (BoNT/A-G)
22                        These findings firmly establish that alterations in innate immunity influence
23                                     Here, we establish that although ICP34.5 binds TBK1 under certain
24                                  Our results establish that, although gamma-2 is not typically associ
25                                      We also establish that an ABC transporter of unknown function, Y
26                                   These data establish that an inactivated RABV-MERS S-based vaccine
27                                We previously established that an insulin-like growth factor 1 (IGF-1)
28                         Furthermore, we have established that ANG-ALS variants which affect the struc
29                                   It is well established that anthropogenic chlorine-containing chemi
30                                We previously established that antibodies are essential for rVSV-EBOV
31                    The present study further establishes that any of the three double-ring building b
32                                   It is well established that, apart from its distinct role in blood
33                   In conclusion, our results establish that APLPs show typical features of SAMs and i
34                               This study has established that, as in schizophrenia, there is a therap
35 on and in vivo analysis of INM targeting, we establish that Atlastins, membrane-bound GTPases of the
36 and other findings in our study conclusively establish that ATM activity poses a major barrier to onc
37      By using chromosome breakpoint data, we established that avian interchromosomal breakpoints appe
38 nd water filtrate from the surrounding ditch established that bacteria of A. filiculoides differed en
39                                    It is now established that Bcl11b specifies T cell fate.
40                       It has previously been established that behavioural variant frontotemporal deme
41 mum Likelihood Structural Equation Modelling established that beverage preferences have a moderate to
42  and co-immunoprecipitation-based assays, we establish that binding at either site increases affinity
43                       This chronological arc establishes that bison first entered North America durin
44 naling concurrent with PASE development, and establish that BMP-SMAD activation/inhibition modulates
45                                   We further establish that BONCAT can be coupled to tandem liquid ch
46                            Twin studies have established that both genes and environment play importa
47                                    Our study establishes that both quantum interference and heteroaro
48                             While it is well established that broad-scale patterns of abiotic and bio
49                             While this value establishes that C-C cleavage is part of the rate-determ
50                 Altogether, our data clearly establish that Ca(2+) entry exerts a feedback control on
51 atic people, a Babesia carriage state can be established that can last up to a year or more.
52                                   It is well established that canonical eukaryotic pre-mRNA 3' proces
53                                   It is well established that cardiorespiratory fitness (CRF) is inve
54                                     Our data establish that cargoes containing Yxxphi motif, but not
55  of demyelination and mice of either sex, we establish that Cav1.2 deletion in OPCs leads to less eff
56 ) OPCs were identified by a Cre reporter, we establish that Cav1.2(KO) OPCs display a reduced maturat
57               Further, magnetic studies have established that Ce3Mn8 exhibits both the combination of
58 tions in animals and post-mortem humans have established that cerebro-cerebellar connections are cont
59                        Multiple studies have established that certain inflammatory disorders and infl
60 brain tumor patients to healthy children, we establish that changes in the microstructure of the opti
61                               These findings establish that cholesterol plays a critical role in modu
62           Over the last decades, it has been established that chronic antigen stimulation during pers
63 disease is poorly understood, although it is established that circulating pathogenic natural IgM, whi
64                             While it is well established that climbing fibre signals are important fo
65                               These findings establish that clinical resistance to quizartinib is hig
66                                   This study establishes that CMV protein pUL31 is necessary and suff
67                                           We established that competition between cytokine diffusion
68                      These data definitively establish that complete structural integrity is necessar
69                                   These data establish that compound 23 (BETd-260/ZBC260) is a highly
70                  Further biochemical studies establish that coordination of Ni(II) at the hexahistidi
71 ever, using deuterated POPC we could clearly establish that COR15A interacts with the membranes and p
72                   Many in vitro studies have established that crystallin proteins precipitate into ag
73                                      We also established that CTL1 is involved in regulating vesicle
74                       Most significantly, we established that CYGB increased the expression of NFsmal
75                               It is now well established that data from FFQs and other self-reported
76              Analysis of Mov10l1(-/-) testes established that de novo methylation of the L1 transgene
77                                 Our findings establish that defective MRM2 causes a MELAS-like phenot
78                     Consequently, this study establishes that DeltaS is proportional to S0 and that t
79                  For many years, it has been established that deregulated expression of transcription
80                           We have previously established that despite the apparent surface uniformity
81                 Taken together, our findings establish that differential expression of several MAPK f
82                   Preliminary work in AD has established that disease-associated T-cell abnormalities
83                                   We further establish that DNA demethylation induced by XPC expressi
84                 Previous investigations have established that DnaB is composed of an N-terminal domai
85                                      Here we establish that DOCK5 has a non-redundant role in regulat
86                                These studies establish that donor age is associated with an increased
87 the Kir2.1(+/-) heterozygous mouse model, we establish that downregulation of Kir2.1 results in signi
88                                These results establish that driver gene mutations are associated with
89                              It was recently established that electrospray ionization mass spectromet
90  of this disease remains unknown, it is well established that endometriosis patients exhibit immune d
91                                    It is now established that epilepsy is characterized by periodic d
92                 Taken together, our findings establish that EVs secreted by AFSC could target a speci
93 zed by an exchange rate [Formula: see text], establishing that FD of Fis occurs at the single-binding
94                  Collectively, these studies establish that female gonadal sex hormones underlie the
95                                        It is established that FHL can operate as a highly efficient h
96                                    This work establishes that Fhod shares the capacity of other formi
97                                   We further established that FI-HSV-2 alone or in combination with a
98                           Thus, our findings establish that fibrotic lung disease is mediated, in par
99                                       It was established that, for thermo-oxidative degradation, Pois
100 g an FRS2,3-binding site mutant of Fgfr1, we established that FRS adapters are necessary for mediatin
101                      Although it is now well established that gammadelta T cells can be rapidly recru
102 r samples, we confirmed this association and established that germline nonsense and frameshift varian
103                                   It is well established that glutamate and GABA signal through both
104                                  Our results establish that Grc3 drives Las1 endoribonuclease cleavag
105                                        It is established that H. pylori stimulates neutrophil chemota
106 histone acetylase and deacetylase activities established that histone acetylation marks are necessary
107                         However, we recently established that HIV-1 can infect kidney transplant epit
108                               These findings establish that holo-RBP and its receptor STRA6 are poten
109               We further used AD-iN cells to establish that human collybistin, the loss of gene funct
110 t none of the experiments they review really establishes that human adults, infants, or nonhuman anim
111                                Whereas it is established that IFNAR1 is an essential component of the
112                         Overall, our results establish that Igf2 LOI is sufficient on its own to incr
113                 Previous work in rodents has established that immune activation during critical devel
114                         These results firmly establish that in HIV-1, CA is a strong determinant of s
115                             We have recently established that in Arabidopsis, the regulator of G-prot
116 ic factors.SIGNIFICANCE STATEMENT This study establishes that in neurogenic niches of an adult diurna
117                          Although it is well established that Influenza A virus infection is initiate
118                Using chemical inhibitors, we established that inhibition of p38, but not ERK or JNK,
119                           These studies have established that, instead of simply balancing excitatory
120 section with single cell transcriptomics, we establish that interferon-stimulated gene expression is
121                               These findings establish that IP6K1 physiologically regulates neuronal
122                              Furthermore, we establish that IR25a and IR76b are essential in sour GRN
123 motility, a leading-lagging cell polarity is established that is inverted during cellular reversals.
124                                   This study establishes that ISG15 itself restricts HCMV replication
125                                 Moreover, it establishes that ISGylation modifies the proteomes of vi
126                                   This study establishes that IUGR also leads to impairment of the ri
127                                  Our results establish that KLF10 functions to suppress TGFbeta-induc
128       Using a mitochondrial fusion assay, we established that L-OPA1 confers fusion competence, where
129 Using real-time single-molecule analysis, we establish that leading- and lagging-strand DNA polymeras
130 ses and a 1.9 A resolution crystal structure established that LigY belongs to the amidohydrolase supe
131                                Previous work established that Lis1, a conserved regulator of dynein,
132                                           We established that loss of miR-874-mediated control of cyc
133  analyses of miR-383 in PCa clinical tissues established that low miR-383 expression is associated wi
134         Using time-resolved spectroscopy, we establish that luminescence via triplets occurs within 3
135                        These results clearly establish that MCs may contribute to host defences to Le
136 ndencies for competing modes of disrotation, establishing that meaningful changes in dynamically cont
137 g of mechano-insensitive formin mutant cells established that mechanoregulation of formin Cdc12 is re
138                           We have previously established that methylerythritol cyclodiphosphate (MEcP
139                          Although it is well established that methylphenidate (MPH) enhances sustaine
140                                   These data establish that Miro1-mediated mitochondrial positioning
141        In macrophages, previous studies have established that mitogen- and stress-activated protein k
142                                These results establish that ML function is crucial for detection of f
143                                     Our work establishes that MLIs in the lateral cerebellum are broa
144                                These results establish that mo-DCs and mo-Macs are controlled by dist
145                                           We establish that monomeric BslA is necessary and sufficien
146 dex of Heart Attack Risk in College Alumni", established that more strenuous PA reduced the risk of h
147                                           We established that more than seven galacturonic acid resid
148                        To this end, we first established that MRgFUS is capable of significantly enha
149                                     Our data establish that MRPS34 is required for normal function of
150 e its contribution at 25 degrees C, our work establishes that Myo2p is the major motor involved in ri
151                               Recent studies established that nascent autophagosomes in distal axons
152                     Ancient DNA studies have established that Neolithic European populations were des
153                       Together, our findings establish that Nep1 and dAbeta expressed in DPM neurons
154                                   It is well established that networks within multiple-demand cortex
155                               These findings establish that neuronal transcriptomic identity correspo
156                   More recently, it has been established that NMDAR-mediated transmission can be dyna
157              Collectively, these experiments establish that not all phagocytic receptors are function
158     Microbiome-wide association studies have established that numerous diseases are associated with c
159                                           We established that oligosaccharide stannanes could be prep
160                                 The findings establish that OMCCs are highly structurally and functio
161                                           We establish that, on timescales relevant to epithelial mor
162 lding or translocation is rate limiting, and establish that one or a few power strokes are sufficient
163 em cell function in vitro as well as in vivo established that only HSCs and not investigated progenit
164 posited as fibrils in the patient's kidneys, establishing that only a small portion of Phe521Leufs di
165                               These findings establish that oocytes generated during adulthood contri
166 cted by a micron-scale magnetic dipole, thus establishing that our sorter can be an instrument for na
167  T-cells from WT and OX40(-/-) mice we first established that OX40 mediated activation of NF-kB was c
168 atients approaching the end of life and well-established that patients and carers hold fears relating
169 chanistic, and in situ spectroscopic studies establish that Pd(II)-mediated C-H activation is the tur
170                          Although it is well established that PD-1-PD-L1 blockade activates T cells,
171                                 Our findings establish that pericytes promote endothelial sprouting,
172                                These studies establish that peripheral markers of FGF2 concentrations
173                             While it is well established that plants associating with arbuscular myco
174                               It is now well established that Polmu is the one adapted to repair DSBs
175                            Many studies have established that populations can evolve a reduced mutati
176  Using an IRES-dependent reporter system, we established that PRMT5 facilitates the translation of a
177                 In recent years, it has been established that programmed cell death protein ligand 1
178 retical and experimental studies have firmly established that protein folding can be described by a f
179 analyses using PTHrP1-17-specific antibodies establish that PTHrP1-17 is indeed generated by cancer c
180                               These findings establish that PXR signaling contributes to ALD developm
181                                We previously established that Rac1 signals via Scar/WAVE and Arp2/3 t
182                            In this study, we establish that RAGE-PR3 interaction mediates homing of p
183 ses of promoter open complex (RPo) formation establish that RbpA and CarD cooperatively stimulate for
184                                   These data establish that recurrent and hierarchical connectivity b
185 endent COS/H2S release from each donor core, establish that release profiles can be modified by struc
186                                   It is well established that resource quantity and elemental stoichi
187                                     Here, we establish that reversed replication forks are a patholog
188          Mechanistic studies in this setting established that RHAMM stabilized F-actin polymerization
189 g pocket conferred resistance to rigosertib, establishing that rigosertib kills cancer cells by desta
190                                  PRIMERS III establishes that RMDs can discriminate between carbapene
191                                           We establish that RNF169 binds to ubiquitylated H2A-Lys13/L
192                                These results establish that RTF2 removal is a key determinant for the
193                                     Here, we establish that S-nitrosoglutathione reductase (GSNOR), a
194                        Photolabeling studies established that S-mTFD-MPPB binds to the same GABAAR in
195  by polyketide synthetase (pks) coding genes established that seaweed-affiliated bacterial flora had
196                                   It is well established that sensory afferents innervating muscle ar
197  (NOS) enzymes, research in recent years has established that significant NO can be derived from diet
198 teracts with Mediator subunit 25 (MED25), we establish that similar, aromatic-rich motifs located bot
199                                  Our studies establish that single-base bulges 7T8, 5A6 and 4A5 on th
200                  Taken together, our results establish that SlRd2, a tomato UspA, is, to our knowledg
201                 Together, these observations establish that small molecules that bind to the interfac
202                                           We establish that SNX5 and SNX6 associate with the CI-MPR t
203 s of patients with HCV infection, we did not establish that sofosbuvir-velpatasvir-voxilaprevir for 8
204                                   It is well established that somatic genomic changes can influence p
205 cute injury, and using this in vivo model we establish that SPAR downregulation enables efficient act
206                                           We establish that species of Streptomyces secrete dodecanoi
207                          Although it is well established that spoken word recognition engages the sup
208    By gain- and loss-of-function studies, we establish that SRC stimulates the secretion of exosomes
209                            Whilst it is well established that statistical and economic considerations
210 inactive (b) conformer with even longer DAD, establishing that stochastic conformational sampling is
211 em.SIGNIFICANCE STATEMENT Prior studies have established that substantia nigra pars compacta (SNc) do
212                                           We establish that substantial changes in vegetation and fir
213                            Previous work has established that such differences in song within a speci
214                       Reciprocal transplants established that survival benefits of GSNOR deletion wer
215                               Although it is established that synaptotagmin cannot rescue the otoferl
216                          In this context, we establish that telomerase binding to reversed replicatio
217                          Mechanistically, we established that TGFbeta is required for D-ECM productio
218 alization and in vitro functional assays, we establish that the "neuron-specific" K(+)Cl(-) co-transp
219                                These results establish that the acquisition of model-based informatio
220          Here, we describe three examples to establish that the approach is simple and generalizable.
221                                           We establish that the domain wall state decomposes into two
222                 Steady-state kinetic studies establish that the enzyme is capable of catalysing imine
223 irescens for performance on P. angulata, and establish that the genetic architecture of intraspecific
224                  Taken together, our results establish that the HAT activity of MOF is required to su
225                                     Our data establish that the histone-based mechanism of DNA compac
226                                     Here, we establish that the HSV-1 Us3 protein kinase subverts the
227                                  Our results establish that the intrinsic probability of a gate enter
228                                     Here, we establish that the ISG15 gene product itself directly re
229                     Together, these findings establish that the LigC complex is directly involved in
230 myosin-5 to microtubule-dependent motors, we establish that the minus end-directed transport of SVs r
231 nctional theory-based transport calculations establish that the new contacts dramatically increase th
232 by employing super resolution microscopy, we establish that the ParF DNA partition protein of the Par
233                                           We establish that the PhoP-activated protein MgtC protects
234                                   These data establish that the PPKs are directly involved in catalys
235                                           We establish that the presence of either D2L or D2S can sup
236                                   These data establish that the RP-MDM2-p53 pathway, in contrast to t
237 cAMP and PKA activity in intact cells and we establish that the sensitivity of PKA to cAMP is almost
238 lity, sensory features, and time constraints establish that the signal reflects an active, feature- a
239                                           We establish that the synaptic modulator reelin (RELN) is a
240                           Now, Boulay et al. establish that the translocated prion-like domain of the
241                                     Our data establish that the vascular adventitia contains phenotyp
242 pentanoate methyl esters (8) by chiral GC-MS established that the BonMT2-catalyzed methylation genera
243 osynthase (KS)-ketoreductase (KR) assay that established that the decarboxylative condensation of met
244                         A baseline condition established that the demonstrated tower design was beyon
245 4 ion images with immunohistochemical images established that the drug was taken up by macrophages as
246                              The last decade established that the dynamic properties of the phosphopr
247   In clinical specimens of breast cancer, we established that the expression of CD44s and HAS2 was po
248  number of motile and immotile cilia, we now established that the final number of motile cilia depend
249 confirmed by single-crystal XRD analysis, we established that the ground state UV-vis absorption of 7
250                      Although it is now well established that the hippocampus supports memory encodin
251                               Although it is established that the host's epigenetic machinery is sens
252                           Additional studies established that the increased toxicity upon mutating Ub
253                             It has been well-established that the known TMs can be classified by the
254 eling, and (1)H and (13)C NMR techniques, we established that the major product, MftA*, is a tyramine
255  m(-1) s(-1) at pH 7.4 and 25 degrees C), we established that the measured decay of the intrinsic PDI
256                          Although it is well established that the number of menstrual cycles and preg
257 ron diffraction experiments at 97 and 75% RH established that the presence of COR15A had no significa
258 ies inexorably age, a number of observations established that the rate of aging is modulated in respo
259                     A competition experiment established that the reaction involves formation of free
260                 However, although it is well established that the receptive field surround is stronge
261 orbital innervation in mice lacking Mafb has established that the stereotypical misinnervation of the
262                      The new evidence firmly establishes that the Al-Cu-Fe alloys (including quasicry
263                                    This work establishes that the self-assembly of ferritin-MOFs is h
264                                         This establishes that the Us3 kinase not only activated mTORC
265                Using the Eyring equation, we established that their activation entropy for rotation i
266                                           We establish that these CRISPR-Cas systems can achieve RNA
267                                 Moreover, we establish that these eGFP(+) cells emerge from a hemogen
268 strations in three-species model systems, we establish that these metrics capture complimentary aspec
269                                           We establish that these microbial consortia act as cartels,
270                     Native mass spectrometry established that these macromolecular assemblies incorpo
271                                   It is well established that these responses are also associated wit
272                                 Recently, we established that these two sodium transport proteins fun
273  defective for interaction with FtsZ, it was established that these ZapA structures form without a co
274 V/vis, CD, and (1)H NMR spectroscopy, it was established that they still function properly as unidire
275                                 Moreover, we establish that this decision is made deterministically,
276 ng a conditional knockdown strategy, we here establish that this kinase is critical for the invasion
277        The use of A2aR-deficient CD4 T cells established that this CGS effect was T cell intrinsic.
278 ents with two hydrophobic fluorescent probes established that this polysaccharide complexes hydrophob
279                                  It has been established that this process involves multi-step electr
280  were 97.3%, 93.9%, and 96.9%, respectively, establishing that this method is capable of reliably pre
281                        Using this method, we established that three key neural markers accounted for
282 rlying mechanism mediating these effects and establish that TLR4 inhibition in the PAG of females rev
283                                   We further establish that TNFalpha induces IR in cardiomyocytes.
284                                     Here, we establish that Toll/NF-kappaB pathway activation in the
285                                      Here we establish that Toxoplasma gondii aspartyl protease 3 (AS
286  Traction force microscopy (TFM) was used to establish that traction stresses are limited primarily t
287                             Functionally, we established that Trx1 protects GC1 from S-nitrosocystein
288 d on amorphous SiO2 as a typical example, we establish that twin defects can be rationally generated
289 ting its utility as a discovery pipeline, we establish that two of these proteins promote ubiquitin-l
290                        Previous studies have established that two molecules of LarE catalyze successi
291 ds, and cDNA sequencing and a splicing assay established that two mutations, including a recurrent si
292                                 Our findings establish that type I IFN-dependent responses, arising f
293                                  Finally, we established that UbFluor can quantify activation or inhi
294 rent: our experimental and modelling results establish that, under these conditions, the ionization o
295                             Our data clearly establish that vascular CXCR4 limits atherosclerosis by
296                        Previous research has established that vehicles directly emit primary aerosol
297                                   It is well established that viral pathogens exploit PD to spread be
298                                           We established that WarA binds to cyclic-di-GMP, which pote
299 n oscillator containing only DNA components, establishing that Watson-Crick base-pairing interactions
300            Low-temperature (13)C NMR spectra established that (Z)-1 was dissolved as a trisolvated mo

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