ライフサイエンスコーパス: ester group

1 tuents, carries a metabolically labile 2',3'-ester group.

2 cotine containing a C-4 boronic acid pinacol ester group.

3 factor-alpha were shown in the plant stanol ester group.

4 l) followed by intramolecular trapping of an ester group.

5 cted alpha-metalation to introduce the alpha-ester group.

6 introducing an ketone group in place of the ester group.

7 lyl cation due to polarization caused by the ester group.

8 ly via the solvent with the aid of the ortho ester group.

9 the acetal, N-benzyl, and alkyl phosphonate ester groups.

10 6-positions with different alkyl, aryl, and ester groups.

11 ation and by direct enzymatic removal of the ester groups.

12 rogen bonds, which alter the dynamics of the ester groups.

13 onality, in pyridine or acetonitrile at both ester groups.

14 with a methanol solvent, resulting in methyl ester groups.

15 es as nucleophiles and then LAH-reduction of ester groups.

16 oss-link, supporting a role for the feruloyl ester groups.

17 ties such as nitro, cyano, dialkylamino, and ester groups.

18 a formyl, a trifluoroacetyl, and two methyl ester groups.

19 e achieved by varying the type and number of ester groups.

20 heat of adsorption to involve 4-6 layers of ester groups.

21 mide backbone that are uncharged, containing ester groups.

22 ra in solution indicated equivalency of both ester groups.

23 he acyclic derivatives with uncharged (e.g., ester) groups.

24 receptor model, shows the bulkier of the two ester groups (5-Bn) of 21 oriented toward the exofacial

25 xymethyl and the 5-[2-(trimethylsilyl)ethyl] ester groups, a free carboxylic acid was formed at the 5

26 Due to the adjacent ester group, alpha-imino esters are more reactive relati

27 ieties, whereas Sc3N@C80-B contains only one ester group and a hydrogen atom on the central carbon of

28 near-symmetric diesters that possess an exo-ester group and an endo-ester group attached on a norbor

29 ifference is the torsional angle between the ester group and the aromatic ring.

30 cytokine production between the plant stanol ester group and the control group were shown.

31 acrylate followed by borane reduction of the ester group and the key 1,3-dipolar cycloaddition step i

32 h respect to the linkage between the boronic ester group and the polymeric backbone: either direct (1

33 oselectivity, depending on the nature of the ester group and the substitution of the cyclic oxo ester

34 By modifying the ester group and thus its susceptibility to esterase, and

35 compounds 1 and 2 containing a single methyl ester group and two carboxylic acids, respectively.

36 metry showed that the conjugate with the two ester groups and ethynyl linker was the most easily redu

37 lowed by LiAlH(4) reduction of the azido and ester groups and N-acylation, complete the synthesis of

38 LiAlH4 caused reduction of all four ester groups and returned 11 after acidic workup.

39 nd dihydropyridine structures, e.g., the two ester groups and the 6-phenyl group.

40 mal activity associated with methyl or ethyl ester groups and with diminished activity resulting from

41 rtially substituted with methyl and O-acetyl ester groups, and rhamnogalacturonan were the main const

42 An ester group appended to a tertiary carbon (C1) was trans

43 When both ester groups are aryl groups the hydrolysis reaction (su

44 (thio)ether substituents, while olefins and ester groups are not compatible with the reaction condit

45 incorporating enzyme-cleavable acetomethoxy ester groups are processed by intracellular esterases an

46 By using an ester group as a surrogate for a methyl group, we were a

47 zobenzene derivatives as monomers and benzyl ester groups as linkages leading to photoresponsive dend

48 Indolizine 6, containing an ester group at C-6, was reductively alkylated to give di

49 r design incorporates a metabolically labile ester group at strategic positions within the THC struct

50 the incorporation of a metabolically labile ester group at the 2'-position on a series of (-)-Delta(

51 ved with methanol/tert-butylamine, while the ester group at the sn-1-position remains unaffected.

52 The alkyl and alkenyl ester groups at C-2 displayed pronounced effects on the

53 The ester groups at C3 in radicals 8b slow the 3-exo cycliza

54 rable steric hindrance between the two large ester groups at the 3- and 3'-positions.

55 s found for stereodirecting participation by ester groups at the 4- and 7-positions.

56 On the other hand, ester groups at the carboxylic position favor ring openi

57 that possess an exo-ester group and an endo-ester group attached on a norbornane or norbornene skele

58 to ISS, which is attributed to Ca binding to ester groups below the CH3/CH2-terminated PMMA surface.

59 comparison to the parent radical lacking an ester group by a factor of 3, an effect ascribed to a po

60 The resulting diols were exchanged for ethyl ester groups by base-catalyzed transesterification.

61 These results indicate that the remote ester group can control the enantioselectivity.

62 forms ortho to the boronic acid or boronate ester group can form a dative N-B bond.

63 ps show low enantioselectivity because small ester groups cannot fill this pocket, while longer ester

64 omputer modeling to identify that the remote ester group controls the enantioselectivity.

65 Introduction of the ester groups did not affect the cytotoxic properties of

66 the stability of more labile FRs containing ester groups (e.g., OPFRs and 2-ethylhexyl-tetrabromo-be

67 Beta-amino ester groups experienced a significant increase in hydro

68 groups cannot fill this pocket, while longer ester groups extend beyond the pocket.

69 in a selective fashion with the hydrophilic ester group facing water and the hydrophobic aryl group

70 ulfide upon esterase-mediated cleavage of an ester group followed by lactonization are described here

71 three carboxylic acid/carboxylate or methyl ester groups for surface binding and a tridentate cyclom

72 Selective cleavage of O2' and O3' ester groups from ribonucleoside derivatives has been ac

73 r one-dimensional pores lined with the ethyl ester groups from the ligand.

74 s having alkene bridges substituted with two ester groups function to give highly emissive, broad, an

75 lowed by saponification of the two remaining ester groups gave 3.

76 In particular, electron-withdrawing ester groups give rise to a 50 nm separation of the n-->

77 one morphinan pharmacophore and a long-chain ester group, had affinity at both micro and kappa recept

78 aining alkyl, aryl, silyl, alkoxy, acyl, and ester groups have been prepared in moderate to good yiel

79 ves substituted by methylenecarboxylic ethyl ester groups have been synthesized in high yields as pot

80 r branched at the alpha-carbon) and aromatic ester groups have been synthesized, their solid-state st

81 xist whether or not water interacts with the ester groups; however, water does accelerate the time-sc

82 The ester group in (Z)-8a accelerates the 3-exo cyclization

83 yzed ring cleavage produce the second methyl ester group in both routes.

84 arding a possible role of the central methyl ester group in establishing an extensive hydrogen bondin

85 The homovanillyl C-20 ester group in RTX (corresponding to the capsaicin 'B-re

86 e due to the influence of the strained ortho ester group in RTX, which acts as a local conformational

87 al results, we show that the presence of the ester group in the backbone of organic substrates can in

88 The initial search for surrogates of the ester group in the screen lead led first to the optimiza

89 The ester group in the second prodrug group comprised a long

90 synthesis, its tolerance to the size of the ester group in the styryldiazoacetates, and its compatib

91 ed an RNA-linked hydroxyfuranone or succinyl ester group, in addition to a number of other putative s

92 posed of a pyrene and a reactive succinimide ester group, interacts with graphene non-covalently via

93 A position 13 lipophilic ester group is required for activity.

94 ine hybrid agents containing carboxylic acid ester groups is described.

95 cers functionalized with carboxylic acid and ester groups is presented.

96 nd the distribution of the pentafluorophenol ester groups is reasonably uniform within the microchann

97 tion of one O-Li bond compound containing an ester group, LiO(CH2)2CO2(CH2)2OCO2Li, then two very com

98 erable lipophilic character, with tert-butyl ester groups located in their peripheral regions.

99 The presence of the ethyl ester groups makes the pores hydrophobic in nature, as d

100 in forming the diester product so the second ester group must arise from the original ketone group.

101 ture of noninterconverting diastereoisomers (ester group of 3b trans to P, 5b; or to N, 5c), which we

102 nyl (C=O) stretch of the butyric acid methyl ester group of a functionalized fullerene, PCBM, is prob

103 Such complexes revealed that the benzoic ester group of both cocaine stereoisomers must rotate to

104 The methyl ester group of cocaine appears to engage in attractive v

105 In tasidotin, the carboxyl-terminal ester group of dolastatin 15 has been replaced by a carb

106 Lastly, computations evidence that the ester group of methyl propiolates enables a divergent me

107 we replaced the potentially labile pipecolic ester group of previous FKBP51 ligands by various low mo

108 against HRV14, and the thiazolyl acetic acid ester group of SDZ 89-124, which is potent against HRV1B

109 The influence of the nature of the ester group of the acrylates in reaction stereoselectivi

110 585) and 2541(2506), thereby reorienting the ester group of the peptidyl-tRNA and making it accessibl

111 ethylesterification by PMEs of the O6-methyl ester groups of the homogalacturonan component of pectin

112 p, on the N-terminus and a bulky, lipophilic ester group on the C-terminus.

113 al groups, including cyano, keto, nitro, and ester groups, on the aryl bromide.

114 modification of the 5-carboxyl group with an ester group or with a thiourea-based moiety were almost

115 normal sperm quality were found in phthalate ester group (OR = 1.52; 95% CI: 1.09-1.95) and organochl

116 Transformation of the ester group permits a wide range of functionality and so

117 cramble the relative orientation of adjacent ester groups, potentially leading to a complex mixture o

118 ween the amido proton and carbonyl oxygen of ester group provides the extra stability to the Z-isomer

119 The succinimide ester group reacts with the amine group to initiate anti

120 nes functionalized with N-hydroxysuccinimide ester groups resulted in the covalent attachment of the

121 (fluoroaryl)glutaric acids with differential ester groups; selective hydrolysis to a mono acid, intra

122 Both smaller and larger ester groups show low enantioselectivity because small e

123 Asthma patients in the plant stanol ester group showed higher antibody titres against HAV 3

124 , intramolecular trapping by the neighboring ester group, subsequent hydrolysis, and loss of methanol

125 shows much less geometric distortion in the ester group than delta-valerolactone, and the notable st

126 layers that have Na(+) ions located near the ester groups than between the two PA bilayers.

127 ) by the presence of an electron-withdrawing ester group that inhibits QM regeneration.

128 These phosphoramidate prodrugs contain an ester group that undergoes intracellular activation libe

129 The prodrugs contain an ester group that undergoes reductive activation intracel

130 e functionalization of the adenine ring, the ester group was converted to the 5'-N-methylamide.

131 ed by catalytic reduction, and the remaining ester group was converted to the corresponding Weinreb's

132 nyl substituent in the 3-position cis to the ester group was found to undergo ring expansion to a mix

133 A bromo intermediate bearing two methyl ester groups was obtained from 1,2,4-trimethylbenzene by

134 tide, which contained a terminal alpha-azido ester group, was treated with DTT/DIPEA.

135 In a first part, pyridazines bearing an ester group were synthesized as a model to evaluate the

136 Alternately, the acid and ester groups were interchanged and heated with diphenylp

137 introduce benzylic substituents alpha to the ester group which affect the half-lives of deactivation

138 of initial nascent Al atoms by the terminal ester group while also revealing formation of isolated,

139 ne of the aromatic ring and the plane of the ester group, while the white form has two different mole

140 of cyclic 2-amino esters, which replaces the ester group with an aryl ring at the sp3 carbon center.

141 Nonpolar interactions of the port side ester group with hydrophobic side chains of Ile-1156, Il

142 The ethyl ester groups within the pores also protect CALF-25 from

143 on of non-hydrocarbon functionalities (i.e., ester groups) within chains that are normally entirely h

144 tained by the hydrolysis of these peripheral ester groups, yielding water-soluble dendrimers with car