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1 ceptor-destroying sialate-O-acetylesterase ("esterase").
2 rough binding the ColQ tail of acetylcholine esterase.
3 minal domain of calmodulin into an efficient esterase.
4 2 is not a potent inhibitor of acetylcholine esterase.
5 tion affecting the catalytic activity of the esterase.
6 , but is efficiently removed by an exogenous esterase.
7 ability to inhibit the enzyme acetylcholine esterase.
8 on the oligomeric assembly of hemagglutinin-esterase.
9 with no significant change in acetylcholine esterase.
10 ied cells that express a substrate-selective esterase.
11 r hydrolysis reactions catalyzed by a serine esterase.
12 of any previously reported de novo designed esterases.
13 as well as controlled deactivation by plasma esterases.
14 esidue peptides that act as Zn(2+)-dependent esterases.
15 of additional not yet characterized lipases/esterases.
16 he consensus motif "GXSXG" characteristic of esterases.
17 Sulfonyl fluorides are known to inhibit esterases.
18 t enzymatically active member of a family of esterases.
19 D-39-type apyrase, adenosine deaminases, and esterases.
20 for the differences in activities in the two esterases.
21 structure of AF-Est2 with the human carboxyl esterase 1, which has CoA thioesterase activity, reveals
22 main with the typical fold of a carbohydrate esterase 4 and an N-terminal domain unique for this fami
23 eta-xylosidase/alpha-arabinosidase, feruloyl esterase, acetylxylan esterase, and a Xanthomonas oryzae
25 accumulation of Abeta, reduced acetylcholine esterase (AChE) activity, and accelerated deterioration
30 he mutant strain lost most of its lipase and esterase activities and displayed reduced virulence in c
31 In S. invicta, male alates had the highest esterase activities followed by workers then female alat
40 esidues are positively correlated with fecal esterase activity and acetate level of human diabetes.
41 Here we explore the minimal requirements for esterase activity by computationally designing artificia
42 he xylanase domain (E280S), the ferulic acid esterase activity increased threefold, which suggests th
43 es in the esterase domain suggested that the esterase activity is derived from a tetrad composed of S
49 binding or provide the protease, lipase, or esterase activity required for entry of the virus into a
53 able microorganisms exhibiting intracellular esterase activity were detected on >90% of both NC types
54 s seem to exhibit no significant protease or esterase activity when tested against analogous substrat
55 Optimized conjugate 16 was designed so that esterase activity will liberate 5 and cathepsin K cleava
58 hosphatidylserine, DNA breaks, intracellular esterase activity, and activation of caspase-8, -9, and
61 are bifunctional enzymes containing a trans-esterase activity, which is responsible for nicking the
74 , temperature and substrate conditions using esterase and caseinolytic activity assays and time cours
75 cies, suggesting that high expression of the esterase and consequent low ester content may provide an
78 characterized a novel periplasmic trilactone esterase and suggested a new model of FeEnt acquisition
79 er hydrolysis reaction catalyzed by a serine esterase and, therefore, one no longer can simply assume
82 rabinosidase, feruloyl esterase, acetylxylan esterase, and a Xanthomonas oryzae putative a-L: -arabin
84 e ester group and thus its susceptibility to esterase, and structural features critical to the lacton
85 ion and activity of the enzyme pectin methyl-esterase, and the chelation of calcium by pectic acids.
86 EGG pathway profiling predicts that kinases, esterases, and hydrolases may contribute to venom activi
90 ibition of pancreatic lipase and cholesterol esterase, as well as cholesterol micelle formation and b
91 ses, polysaccharide lyases, and carbohydrate esterases, as well as accessory, redox-active enzymes fo
93 lysis but is a highly reactive substrate for esterases both in vitro and in cellulo, yielding a brigh
94 or their capacities to inhibit acetylcholine esterase but, in contrast to the predictions from dockin
95 r masking motif that is stable to endogenous esterases, but is efficiently removed by an exogenous es
96 The sulfocoumarins were hydrolyzed by the esterase CA activity to 2-hydroxyphenyl-vinylsulfonic ac
97 Unlike coumarins which are hydrolyzed by the esterase CA activity to the corresponding 2-hydroxy-cinn
98 knockdown approach, we identified a specific esterase, carboxylesterase 1, whose function had a clear
99 on until entry into a cell, where endogenous esterases catalyze the hydrolysis of the masking groups,
100 tified a mutant G4C/S10C/T172R/G173Q cocaine esterase (CCRQ CocE) with an in vitro duration of action
101 hat is a member of the family 4 carbohydrate esterases (CE4s) and a domain structurally similar to gl
102 arrel common to the family four carbohydrate esterases (CE4s) with the canonical motifs circularly pe
105 ssay for total cholesterol using cholesterol esterase/cholesterol oxidase coupled with the luminol-H2
107 polyethylene glycol (PEG)ylated lipids with esterase-cleavable linkers (e.g., ME42) to promote intra
110 d that administration of a cocaine hydrolase/esterase (CocH/CocE) can considerably decrease the cocai
111 four members but lacks the canonical lipase/esterase consensus catalytic sequences, and their enzyma
113 ave previously identified caffeoyl shikimate esterase (CSE) as an enzyme in the monolignol biosynthes
115 -5-hydroxylase (F5H), and caffeoyl shikimate esterase (CSE), were targeted by MYB31 or MYB42, but in
116 of E. coli H1187 (fepA-) or the enterobactin esterase-deficient derivative of E. coli K-12 JW0576 (fe
118 we have developed a mutant bacterial cocaine esterase (DM-CocE), which has been previously shown to r
119 inds to a conserved epitope in the vestigial esterase domain of hemagglutinin (HA) and blocks HA-medi
120 highly conserved active-site residues in the esterase domain suggested that the esterase activity is
123 y modest architectural changes in lectin and esterase domains; and (iii) a single, inconspicuous Ala-
124 articles are fully degradable in response to esterases due to an embedded ester cross-linker in the p
125 due to the activity of beta-glucosidase and esterase during the first months of storage and then a s
126 enes S85 Axe6B (FSUAxe6B) is an acetyl xylan esterase encoded in the genome of this rumen bacterium.
131 the first structure of a full-length AT, the esterase EstA from Pseudomonas aeruginosa, at a resoluti
134 of glutathione-S-transferase (GST), general esterases (ESTs) and phenol oxidase (PO) decreased in th
135 All of the new VoltageFluors targeted by esterase expression (VF-EXs) report single spikes in cul
137 sterase domains in BiFae1B with the feruloyl esterase from Clostridium thermocellum suggest that both
142 rain bacteriuria (from 7% to 69%), leukocyte esterase (from 31% to 64%), and symptoms (from 3% to 43%
143 of eight aliphatic polyesters by two fungal esterases (FsC and Rhizopus oryzae lipase) at different
145 ce in cells expressing tobacco pectin methyl esterase fused to green fluorescent protein (PME-GFP).
147 y a chimeric influenza C virus hemagglutinin/esterase/fusion (HEF) segment carrying the HA packaging
148 hat the recently characterized acetylcholine esterase gene, choE (PA4921), is also regulated by GbdR.
149 n(2+) bimetallo core is an effective mono/di-esterase generalist and that the bimetallo cores were no
150 tudy provides evidence that purified O. oeni esterases have the ability to both synthesise and hydrol
154 complex of the ISAV F and ISAV hemagglutinin esterase (HE) proteins in an unknown stoichiometry prior
158 fferences were observed and strains with low esterase hydrolysis activity against artificial substrat
159 QALs, FQALs) selectively, while chlorogenate esterase hydrolyzed all chlorogenic acids (CQAs, FQAs) a
163 t drug 1 in vivo by alkaline phosphatase and esterase in a stepwise manner, providing higher exposure
168 usceptible to enzymatic hydrolysis by plasma esterases in a controllable manner, while their metaboli
171 ts received intravenous recombinant human C1 esterase inhibitor (50 IU/kg; maximum 4200 IU) twice wee
172 cks of hereditary angioedema (HAE) due to C1 esterase inhibitor (C1-INH) deficiency (C1-INH-HAE) incl
176 fusion of C1-esterase inhibitor increased C1-esterase inhibitor (p < .005 vs. control on days 2, 3, a
178 study, patients in the lowest quartile of C1-esterase inhibitor activity in combination with high C-r
180 study assesses the influence of high-dose C1-esterase inhibitor administration on systemic inflammato
183 assess the efficacy of recombinant human C1 esterase inhibitor for prophylaxis of hereditary angio-o
189 randomized to receive either 12,000 U of C1-esterase inhibitor infusions in addition to conventional
190 4200 IU) twice weekly, recombinant human C1 esterase inhibitor once weekly and placebo once weekly,
191 ATION: Prophylaxis with recombinant human C1 esterase inhibitor provided clinically relevant reductio
192 n hIL1ra(Ast)(+/+) mice, the cholinergic ACh esterase inhibitor pyridostigmine increases ACh levels a
194 XII-driven coagulation and the ability of C1-esterase inhibitor to bind and inhibit activated FXII we
195 nificantly reduced with recombinant human C1 esterase inhibitor twice weekly (2.7 attacks [SD 2.4]) a
196 ents given twice-weekly recombinant human C1 esterase inhibitor, 13 (45%) of 29 patients given the on
199 y plasmin, escape from inhibition through C1 esterase inhibitor, and elicit excessive bradykinin form
200 lated to treatment with recombinant human C1 esterase inhibitor, but both resolved without additional
202 rmacokinetic profile of recombinant human C1 esterase inhibitor, our results suggest that efficacy of
203 ery 60 s while neostigmine, an acetylcholine esterase inhibitor, was infused into the medial prefront
205 unctional proteome analysis using lipase and esterase inhibitors revealed a subset of candidate genes
206 bled eight copies of a C3-symmetric trimeric esterase into a well-defined octahedral protein cage by
207 shown that high expression of a non-specific esterase is critical for the low overall ester content o
208 shown that high expression of a non-specific esterase is critical for the low overall ester content o
209 The usefulness of wild-type (wt) cocaine esterase is hampered by its inactivation at 37 degrees C
210 falciparum Prodrug Activation and Resistance Esterase) is required for activation of esterified pepst
211 sly determined a crystal structure of the JH esterase (JHE) of the tobacco hornworm Manduca sexta (Ms
212 io-3-oxobutyl groups have been introduced as esterase-labile phosphodiester protecting groups that ad
213 ized and tested as a substrate for leukocyte esterase (LE), an enzyme produced by leukocytes (white b
214 the Xf secretome revealed a putative lipase/esterase (LesA) that was abundantly secreted in bacteria
215 mal UA finding (greater-than-trace leukocyte esterase level, positive nitrite test result, or pyuria)
218 YTYL ESTER SYNTHASE1 [PES1] and PES2) of the esterase/lipase/thioesterase family of acyltransferases
219 ty of catalytic tandem reactions that employ esterases, lipases or alcohol dehydrogenases and gold(I)
220 Prodrugs that release hydrogen sulfide upon esterase-mediated cleavage of an ester group followed by
221 Importantly, we also demonstrate that the esterase-mediated rapid lysis of M. tuberculosis signifi
222 crystal structure of the metal-ion dependent esterase MGS0169 from the amidohydrolase superfamily rev
227 g protein 6, also known as neuropathy target esterase (NTE), which is the target of toxic organophosp
228 that LipC is a novel cell surface-associated esterase of M. tuberculosis that is highly immunogenic a
231 ophytic fungus Eupenicillium shearii FREI-39 esterase on halloysite, using graphite powder, multi-wal
233 stick analyses for the presence of leukocyte esterase or nitrites, microscopic analysis for white blo
234 ding reactivity, inhibition of acetylcholine esterase or uncoupling of oxidative phosphorylation.
235 on level of specific enzymes like proteases, esterases or glycosidases is often higher in tumor cells
236 DA-ZP1-TPP is insensitive to intracellular esterases over a 2-h period and is impervious to proton-
237 gene expression in the cancer cells high in esterases over fibroblasts low in esterase activity.
238 t in TraB proteins, but also in erythromycin esterase (Pfam ID: PF05139), DUF399 (domain of unknown f
239 9P, in Pseudomonas fluorescens (SIK WI) aryl esterase (PFE) increased the specificity constant of PFE
240 nt parasite mutants, we find that a parasite esterase, PfPARE (P. falciparum Prodrug Activation and R
241 with the surface glycoprotein hemagglutinin esterase phylogeny, were observed between the two lineag
244 an be removed by the action of porcine liver esterase (PLE) to reveal the bright unmodified VoltageFl
246 esterification via decreasing pectin methyl esterase (PME) activity in roots and leaves under unstre
247 The inactivation kinetics of pectin methyl esterase (PME) during the shelf life (4 degrees C-180 da
248 ntially demethyl esterified by pectin methyl esterase (PME) to strengthen or loosen plant cell walls
249 ppressed by a null allele of a pectin methyl esterase (PME3) whose activity normally leads to cross-l
250 gues seem the sole pimeloyl-ACP methyl ester esterase present in the Helicobacter species and their o
253 probable 9-O-acetyl N-acetylneuraminic acid esterase required for E. coli to grow on this alternativ
255 hydrophilic polyethylene glycol (PEG) and an esterase-responsive hydrophobic dendron, to prepare and
256 is insertion causes higher expression of the esterase, resulting in the reduced levels of multiple es
261 eal a conserved epitope in the HA1 vestigial esterase subdomain that is some distance from the recept
263 core of the transition in lectin ligand and esterase substrate specificity; (ii) in consequence, the
267 es were evaluated with nitrite and leukocyte esterase tests, using urine culture and/or dipslide with
268 ble antimalarial; (2) PfPARE is a functional esterase that is capable of activating prodrugs; (3) Mut
270 work has shown that Oenococcus oeni produces esterases that are capable of hydrolysing artificial sub
271 ilarity to a class of proteins that includes esterases, the heme-binding protein ChaN, and an unchara
272 ast to previously described chlorogenic acid esterases, the reUmChlE was also active towards feruloyl
274 he persulfide prodrug can be activated by an esterase to generate a "hydroxymethyl persulfide" interm
275 f taurine and D-peptide allows intracellular esterase to trigger intracellular self-assembly of the D
278 posure) and b) can be metabolized by porcine esterases to TBMEHP, which c) elicited maternal thyrotox
280 uorescent probe are cleaved by intracellular esterases to yield the corresponding negatively charged,
281 rability and efficacy of a novel cholesterol esterase transfer protein (CETP) inhibitor TA-8995 in pa
286 conserved protein domain carrying an acetyl esterase was found to be associated with at least one ta
287 rgistic combination of xylanase and feruloyl esterase was found to be the most efficient enzymatic tr
288 tyl Neu5Ac by lentiviral transduction of the esterase was lethal to ALL cells in vitro even in the pr
290 e, by expressing an intracellular form of JH esterase, we demonstrate that JH must enter the cell in
292 creted glycoside hydrolases and carbohydrate esterases were identified in the genome, revealing a div
293 ALE: Phosphodiesterase 2 is a dual substrate esterase, which has the unique property to be stimulated
294 Phosphodiesterase 2 is a dual substrate esterase, which has the unique property to be stimulated
296 or CB receptors and is deactivated by plasma esterases while the respective acid metabolite is inacti
297 It has been demonstrated to be a serine esterase with sequence similarity to the family CE-3 car
300 encode a bifunctional xylanase-ferulic acid esterase (xyn10D-fae1A) and expressed the recombinant pr
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