ライフサイエンスコーパス: estrogen receptor alpha

1 l lineage specification, including FOXA1 and estrogen receptor alpha.

2 ty in E2-exposed HEK293T cells co-expressing estrogen receptor alpha.

3 d the ligand-dependent activation domains of estrogen receptor alpha.

4 receptor coactivator 2, which interacts with estrogen receptor alpha.

5 CD133(hi) CSCs that expressed low levels of estrogen receptor alpha.

6 e genes; vitellogenin, androgen receptor and estrogen receptor alpha.

7 tein-coupled estrogen receptor (GPER/GPR30), estrogen receptor alpha-36 (ERalpha36), epidermal growth

8 We apply the model to data from estrogen receptor alpha activation in the MCF-7 breast c

9 n response element (ERE) sequence to inhibit estrogen receptor-alpha activities.

10 egree show a greater effect on the levels of estrogen receptor-alpha activity and nuclear factor eryt

11 confirmed that in hypoxic mice inhibition of estrogen receptor alpha also has a therapeutic effect sp

12 Hepatic transcripts of VTG and estrogen receptor-alpha also were affected at DES concen

13 cription activity and directly interact with estrogen receptor alpha, although ACTN4 (Iso) binds ERal

14 ation between maternal LG and mRNA levels of estrogen receptor alpha and beta and the oxytocin recept

15 n regulating the transcriptional activity of estrogen receptor alpha and controlling the expression o

16 E2 substantially increases CaM binding to estrogen receptor alpha and GPER/GPR30.

17 ling components and diminished expression of estrogen receptor alpha and progesterone receptor, which

18 iption factor, which interacts directly with estrogen receptor alpha and regulates the expression of

19 stic disease and cancers retained functional estrogen receptor alpha and responded to retreatment wit

20 stone acetylation and recruitment of phospho-estrogen receptor alpha and specificity protein-1 to the

21 rogen binding to nuclear estrogen receptors (estrogen receptor-alpha and estrogen receptor-beta), whi

22 cally, estrogen activity is mediated via the estrogen receptors alpha and beta (ERalpha and ERbeta),

23 ith low micromolar potency, selectivity over estrogen receptors alpha and beta and glucocorticoid rec

24 It shows no affinity to the estrogen receptors alpha and beta and good intracellular

25 and glial profiles containing the classical estrogen receptors alpha and beta, and synaptic levels i

26 7beta-HSD5, 11beta-HSD1, 11beta-HSD2 and the estrogen receptors alpha and beta.

27 Furthermore, uterine ILC2s highly expressed estrogen receptor alpha, and in vitro culture of isolate

28 ough repression of E-cadherin, occludin, and estrogen receptor-alpha, and up-regulation of vimentin,

29 d this increase was not affected by the pure estrogen receptor alpha antagonist ICI 182780.

30 Estrogen and estrogen receptor alpha are required for the development

31 Estrogen and its nuclear receptor, estrogen receptor alpha, are necessary cofactors in the

32 r of genome-wide analyses have revealed that estrogen receptor alpha binding to and regulation of its

33 e chromatin architecture and allow FOXA1 and estrogen receptor alpha binding to transcriptional regul

34 entify estrogen receptor 1 (ESR1; previously estrogen receptor alpha) binding sites, and RNA-seq in e

35 ecreases the transcriptional activity of ER (estrogen receptor)-alpha but not ERbeta through the modu

36 Expression of estrogen receptor alpha changes across development in a

37 tration decreased AIRE thymic expression and estrogen receptor alpha-deficient mice did not show a se

38 In mice lacking the liver estrogen receptor alpha, E2 after OVX limited adiposity

39 isplayed affinity for aromatase (Ki 442 nM), estrogen receptor-alpha (EC50 17 nM), and estrogen recep

40 (E)-norendoxifen were aromatase (Ki 48 nM), estrogen receptor-alpha (EC50 58.7 nM), and estrogen rec

41 we found 3 lncRNA genes are associated with estrogen receptor alpha (ER) positive and ER negative su

42 The majority of human breast cancer is estrogen receptor alpha (ER) positive.

43 Knockdown of RAD21 altered estrogen receptor alpha (ER) recruitment at SOX4 and IL2

44 ox protein A1 (FOXA1) is a pioneer factor of estrogen receptor alpha (ER)-chromatin binding and funct

45 Estrogen receptor alpha (ER)-positive breast cancers ada

46 rovides a temporary relief for patients with estrogen receptor alpha (ER)-positive breast cancers.

47 Resistance of the estrogen receptor alpha (ER)-positive, chemosensitive MC

48 ng, we used an integrative approach to study estrogen receptor alpha (ER).

49 Androgen receptor (AR) and estrogen receptor alpha (ER-alpha) activity is higher in

50 T2 promoter activity when cotransfected with estrogen receptor alpha (ER-alpha) after 17beta-estradio

51 heir abilities to inhibit aromatase, bind to estrogen receptor alpha (ER-alpha) and estrogen receptor

52 Estrogen receptor alpha (ER-alpha) is a nuclear hormone

53 Approximately 80% of breast cancers are estrogen receptor alpha (ER-alpha) positive, and althoug

54 The estrogen receptor alpha (ER-alpha) regulates expression

55 ed, dramatic estrogen-induced recruitment to estrogen receptor alpha (ER-alpha)-bound eRNA(+) active

56 Drugs that inhibit estrogen receptor-alpha (ER) activity have been highly s

57 Herein, we probed estrogen receptor-alpha (ER) and progesterone receptor (

58 The role of estrogen receptor-alpha (ER) in breast cancer developmen

59 Estrogen receptor-alpha (ER) is an important target both

60 Estrogen receptor-alpha (ER) is the key feature of most

61 Tamoxifen is effective for treating estrogen receptor-alpha (ER) positive breast cancers.

62 e I IGF receptor (IGF1R) in combination with estrogen receptor-alpha (ER) targeting have been complet

63 oligomerization states and mutants of GR and estrogen receptor-alpha (ER), which permitted us to reso

64 hile more than 70% of breast cancers express estrogen receptor-alpha (ER+), endocrine therapies targe

65 ied BRCA1 knockdown resulting in the loss of Estrogen Receptor-alpha (ER-alpha) expression and other

66 cord injury (SCI), or the involvement of the estrogen receptor-alpha (ER-alpha) in locomotor recovery

67 duce tamoxifen resistance through decreasing estrogen receptor-alpha (ER-alpha) level when cultured w

68 HE4 was found to interact with estrogen receptor-alpha (ER-alpha), and HE4 overexpressi

69 s characterized by the lack of expression of estrogen receptor-alpha (ER-alpha), progesterone recepto

70 the expression of luminal markers, including estrogen receptor-alpha (ER-alpha, encoded by ESR1).

71 women, and over two-thirds of cases express estrogen receptor-alpha (ER-alpha, encoded by ESR1).

72 The protein association of estrogen receptor alpha ERalpha with DNA-bound SP1 and C

73 Estrogen receptor alpha (ERalpha) activation functions A

74 opment is controlled by the balance of AR to estrogen receptor alpha (ERalpha) activity; either inhib

75 cals and drugs in three independent runs for estrogen receptor alpha (ERalpha) agonist and antagonist

76 demonstrate that Icaritin co-localizes with estrogen receptor alpha (ERalpha) and activates its nucl

77 eural aromatase, androgen receptor (AR), and estrogen receptor alpha (ERalpha) and beta (ERbeta) mRNA

78 Approximately 75% of breast cancers express estrogen receptor alpha (ERalpha) and depend on estrogen

79 plexes involving RNA polymerase II (Pol II), estrogen receptor alpha (ERalpha) and ERalpha-pioneer fa

80 rapidly induced genes are enriched for both estrogen receptor alpha (ERalpha) and FOXA1 binding in t

81 miR-515-5p is transcriptionally repressed by estrogen receptor alpha (ERalpha) and functions as a tum

82 Estrogen receptor alpha (ERalpha) and progesterone recep

83 shock protein 27 (Hsp27) binds to a motif in estrogen receptor alpha (ERalpha) and promotes palmitoyl

84 nto account the signaling cross-talk between estrogen receptor alpha (ERalpha) and the human epiderma

85 s between the progesterone receptor (PR) and estrogen receptor alpha (ERalpha) are required for PR ac

86 Most breast cancers expressing the estrogen receptor alpha (ERalpha) are treated successful

87 Since LMO4 is known to interact with estrogen receptor alpha (ERalpha) at the promoters of ta

88 Cofactors for estrogen receptor alpha (ERalpha) can modulate gene acti

89 This hypothesis was validated in the estrogen receptor alpha (ERalpha) ChIA-PET data.

90 s direct visualization and quantification of estrogen receptor alpha (ERalpha) DNA binding, co-regula

91 Breast cancers with estrogen receptor alpha (ERalpha) expression are often m

92 Estrogen receptor alpha (ERalpha) expression is critical

93 pid metabolism and body weight by repressing estrogen receptor alpha (ERalpha) expression.

94 Notably, mice with selective deletion of estrogen receptor alpha (ERalpha) from Kiss1 neurons sho

95 Somatic mutations in the estrogen receptor alpha (ERalpha) gene (ESR1), especiall

96 Young female rats express more estrogen receptor alpha (ERalpha) immunolabeling in CA1s

97 Nucleosomes prevent the binding of estrogen receptor alpha (ERalpha) in absence of ligand a

98 ctions of glucocorticoid receptors (GRs) and estrogen receptor alpha (ERalpha) in breast cancer devel

99 and mobilization, processes that depend upon estrogen receptor alpha (ERalpha) in HSCs.

100 rginine transition at residue 303 (K303R) in estrogen receptor alpha (ERalpha) in invasive breast can

101 that conditional knockout (cKO) mice lacking estrogen receptor alpha (ERalpha) in oviduct and uterine

102 Activation of estrogen receptor alpha (ERalpha) in the brain prevents

103 Estrogen receptor alpha (ERalpha) is a critical prognost

104 Estrogen receptor alpha (ERalpha) is a key regulator of

105 Estrogen receptor alpha (ERalpha) is a ligand-activated

106 Estrogen receptor alpha (ERalpha) is a ligand-dependent

107 Estrogen receptor alpha (ERalpha) is a ligand-dependent

108 Estrogen receptor alpha (ERalpha) is a major regulator o

109 Estrogen receptor alpha (ERalpha) is a master driver of

110 Estrogen receptor alpha (ERalpha) is an important target

111 The estrogen receptor alpha (ERalpha) is expressed in approx

112 Estrogen receptor alpha (ERalpha) is highly expressed in

113 The estrogen receptor alpha (ERalpha) is highly expressed in

114 Estrogen receptor alpha (ERalpha) is initially expressed

115 Estrogen receptor alpha (ERalpha) is involved in numerou

116 To assess this, we developed a point mutant estrogen receptor alpha (ERalpha) knockin mouse (C451A)

117 All compounds were high affinity estrogen receptor alpha (ERalpha) ligands but displayed

118 The nuclear hormone receptor estrogen receptor alpha (ERalpha) mediates the actions o

119 Estrogen receptor alpha (ERalpha) mediates the effects o

120 The human estrogen receptor alpha (ERalpha) mediates the prolifera

121 imilarly, castration significantly increased estrogen receptor alpha (ERalpha) mRNA expression and de

122 ival rates of breast cancer patients lacking estrogen receptor alpha (ERalpha) negatively correlated

123 Estrogens can signal through either estrogen receptor alpha (ERalpha) or beta (ERbeta) to am

124 capitulated by pharmacological activation of estrogen receptor alpha (ERalpha) or ERbeta in a rat bet

125 thesized that upregulating the expression of estrogen receptor alpha (ERalpha) or estrogen receptor b

126 Drugs that inhibit estrogen receptor alpha (ERalpha) or that block the prod

127 Estrogen receptor alpha (ERalpha) plays an important rol

128 D538G is common after endocrine therapy for estrogen receptor alpha (ERalpha) positive breast cancer

129 Almost 70% of breast cancers are estrogen receptor alpha (ERalpha) positive.

130 Estrogen triggers transactivation coupled estrogen receptor alpha (ERalpha) proteolysis, but mecha

131 Estrogen receptor alpha (ERalpha) regulates gene transcr

132 Estrogen receptor alpha (ERalpha) regulates gene transcr

133 The DNA-binding sites of estrogen receptor alpha (ERalpha) show great plasticity

134 We initiated studies that examined estrogen receptor alpha (ERalpha) signaling in the tissu

135 Estrogen receptor alpha (ERalpha) signaling leads to cel

136 cell line MCF7, which expresses a functional estrogen receptor alpha (ERalpha) signaling pathway.

137 wledge previously unreported, a role whereby estrogen receptor alpha (ERalpha) signaling preferential

138 In vitro, estrogen receptor alpha (ERalpha) signaling through meta

139 nd animal model results linking estrogen and estrogen receptor alpha (ERalpha) to CxCa, ERalpha expre

140 lective loss- or gain-of-function mutants of estrogen receptor alpha (ERalpha) to define two distinct

141 P140 in breast cancer and its involvement in estrogen receptor alpha (ERalpha) transcriptional regula

142 ecule antagonist of the transcription factor estrogen receptor alpha (ERalpha) used to treat breast c

143 regulates gene transcription through nuclear estrogen receptor alpha (ERalpha) via 2 activation funct

144 P-Int3/WC/R26 mammary glands contained ample estrogen receptor alpha (ERalpha)+ MECs, but only rare (

145 Estrogen receptor alpha (ERalpha), a key driver of growt

146 rogen-based therapies are mainly mediated by estrogen receptor alpha (ERalpha), a nuclear receptor th

147 ivator-6 (NCOA6), a reported coactivator for estrogen receptor alpha (ERalpha), actually attenuates E

148 he genome-wide chromatin-binding profiles of estrogen receptor alpha (ERalpha), along with the epigen

149 strogens drive breast carcinogenesis via the estrogen receptor alpha (ERalpha), androgens play a crit

150 gen-responsive genes, vitellogenin (VTG) and estrogen receptor alpha (ERalpha), as well as the androg

151 Treatment of female rats with antisense to estrogen receptor alpha (ERalpha), but not beta (ERbeta)

152 contribute to the oncogenic potential of the estrogen receptor alpha (ERalpha), but SIRT1 activity ha

153 ons of E2 with one of its cognate receptors, estrogen receptor alpha (ERalpha), estrogen receptor bet

154 Estrogen, via estrogen receptor alpha (ERalpha), exerts several benefi

155 We show that estrogen, acting via estrogen receptor alpha (ERalpha), induces rapid anticip

156 campus of female rats through a sex-specific estrogen receptor alpha (ERalpha), mGluR, and endocannab

157 The transcriptional activity of estrogen receptor alpha (ERalpha), the key driver of bre

158 ntermembrane space (IMS) and mediated by the estrogen receptor alpha (ERalpha), was found to upregula

159 Female lupus-prone NZM2410 estrogen receptor alpha (ERalpha)-deficient mice are pro

160 Estrogen receptor alpha (ERalpha)-estrogen response elem

161 Estradiol acts via estrogen receptor alpha (ERalpha)-expressing afferents o

162 ty to antiestrogens and chemotherapeutics in estrogen receptor alpha (ERalpha)-positive and triple-ne

163 Recurrent estrogen receptor alpha (ERalpha)-positive breast and ov

164 Many estrogen receptor alpha (ERalpha)-positive breast cancer

165 One third of the patients with estrogen receptor alpha (ERalpha)-positive breast cancer

166 Patients with estrogen receptor alpha (ERalpha)-positive breast cancer

167 s COX-2 activity, is associated with reduced estrogen receptor alpha (ERalpha)-positive breast cancer

168 y used endocrine agents for the treatment of estrogen receptor alpha (ERalpha)-positive breast cancer

169 Many estrogen receptor alpha (ERalpha)-positive breast cancer

170 hway in 20% to 40% of cases, particularly in estrogen receptor alpha (ERalpha)-positive breast cancer

171 ly able to reduce DCIS risk in patients with estrogen receptor alpha (ERalpha)-positive disease.

172 herapy occurs in virtually all patients with estrogen receptor alpha (ERalpha)-positive metastatic br

173 ion and histone modifications, are linked to estrogen receptor alpha (ERalpha)-positive tumors and di

174 e: estrogen receptor 1 (ESR1), which encodes estrogen receptor alpha (ERalpha).

175 of BSEP by E2 in vitro and in vivo required estrogen receptor alpha (ERalpha).

176 ported to involve the activation of CHOP and estrogen receptor alpha (ERalpha).

177 fully applied for detection of the biomarker estrogen receptor alpha (ERalpha).

178 the activation and nuclear translocation of estrogen receptor alpha (ERalpha).

179 which can be eliminated by an antagonist of estrogen receptor alpha (ERalpha).

180 he growth of breast cancers that express the estrogen receptor alpha (ERalpha).

181 Therapies targeting estrogen receptor alpha (ERalpha, encoded by ESR1) have

182 ERT) mRNA expression and cell growth through estrogen receptor-alpha (ERalpha) activation in ovarian

183 Estrogen receptor-alpha (ERalpha) activity in the brain

184 as a critical role in the regulation of both estrogen receptor-alpha (ERalpha) and c-ErbB2/HER2 (Her2

185 ely 25% of breast cancers do not express the estrogen receptor-alpha (ERalpha) and consequently do no

186 ities of ZYC-26 and ZYC-3 were autonomous of estrogen receptor-alpha (ERalpha) and ERbeta demonstrate

187 Estrogen receptor-alpha (ERalpha) and progesterone recep

188 ently identified LMTK3 as a regulator of the estrogen receptor-alpha (ERalpha) and wished to understa

189 t regimens for breast cancer that target the estrogen receptor-alpha (ERalpha) are effective, but acq

190 is rescue was accompanied by an induction in estrogen receptor-alpha (ERalpha) expression and that co

191 s to investigate in vivo the role of central estrogen receptor-alpha (ERalpha) expression for bone ma

192 We selectively deleted estrogen receptor-alpha (ERalpha) from either neurons or

193 Estrogen receptor-alpha (ERalpha) has central role in ho

194 The levels of estrogen receptor-alpha (ERalpha) impact breast cancer c

195 s shown to be a transcriptional activator of estrogen receptor-alpha (ERalpha) in ERalpha-positive br

196 The detection of estrogen receptor-alpha (ERalpha) in osteoblasts and ost

197 blocked in female mice specifically lacking estrogen receptor-alpha (ERalpha) in serotonin (5-HT) ne

198 as associated with a significant decrease of estrogen receptor-alpha (ERalpha) in the hippocampus but

199 Estrogen receptor-alpha (ERalpha) is a central transcrip

200 Estrogen receptor-alpha (ERalpha) is an important biomar

201 p) on neutralizing epigenetic aberrations in estrogen receptor-alpha (ERalpha) leading to enhanced an

202 that resveratrol acts as a pathway-selective estrogen receptor-alpha (ERalpha) ligand to modulate the

203 Estrogen receptor-alpha (ERalpha) mediates the essential

204 1 (GCM1), frizzled 5 (FZD5), WNT2, Sp1, and estrogen receptor-alpha (ERalpha) mRNA, were markedly up

205 models that allow for selective deletion of estrogen receptor-alpha (ERalpha) or selective inhibitio

206 Estrogen receptor-alpha (ERalpha) plays an important rol

207 Approximately 75% of breast cancers are estrogen receptor-alpha (ERalpha) positive, underscoring

208 BZA also down-regulated estrogen receptor-alpha (ERalpha) protein by increasing

209 The gene encoding estrogen receptor-alpha (ERalpha) protein is expressed i

210 provided a detailed view of the mechanism of estrogen receptor-alpha (ERalpha) regulated gene transcr

211 We show that activation of estrogen receptor-alpha (ERalpha) stimulates neural firi

212 ly labeled neurons directed to WAT expressed estrogen receptor-alpha (ERalpha), and fewer neurons to

213 males and females is primarily mediated via estrogen receptor-alpha (ERalpha), encoded by the Esr1 g

214 including metalloestrogens that can activate estrogen receptor-alpha (ERalpha), may contribute to bre

215 er subtypes are defined by the expression of estrogen receptor-alpha (ERalpha)-associated genes, many

216 red methylation that preferentially affected estrogen receptor-alpha (ERalpha)-binding genes.

217 Location analysis for estrogen receptor-alpha (ERalpha)-bound cis-regulatory e

218 CAF) in both wild-type (WT) and K303R mutant estrogen receptor-alpha (ERalpha)-expressing breast canc

219 ns, and induced proliferation in parallel in estrogen receptor-alpha (ERalpha)-negative mammary cells

220 herapy resistance remains a major problem in estrogen receptor-alpha (ERalpha)-positive breast cancer

221 nefitted tremendously from the generation of estrogen receptor-alpha (ERalpha)-targeted therapies, bu

222 of breast cancers are driven by estrogen via estrogen receptor-alpha (ERalpha).

223 rotein 90 chaperone complexes, together with estrogen receptor-alpha (ERalpha).

224 This process is mediated by estrogen receptor-alpha (ERalpha).

225 Estrogen receptor-alpha (ERalpha, ESR1) is a pivotal tra

226 s the estrogen receptor needed for feedback (estrogen receptor alpha [ERalpha]); kisspeptin neurons i

227 e), and mice with knockout of Esr1, encoding estrogen receptor alpha (ERalphaKO mice), to analyze int

228 this effect was absent in mice lacking liver estrogen receptor alpha (Esr1) (LERKO mice).

229 tion of MCF7 and SK-BR-3 colony formation by estrogen receptor alpha (ESR1) and (ERBB2) siRNA, respec

230 The results showed an increase in estrogen receptor alpha (esr1) and vitellogenin (vtg) ge

231 uctal epithelial cells are regulated through estrogen receptor alpha (ESR1) but not estrogen receptor

232 Attenuation of estrogen receptor alpha (Esr1) expression by siRNA media

233 -induced uterine cell growth, we removed the estrogen receptor alpha (Esr1) from mouse uterine stroma

234 VAMP7 colocalized with estrogen receptor alpha (ESR1) in the presence of its co

235 Importance: Estrogen receptor alpha (ESR1) mutations found in metast

236 ceptor gene, a mutation in the gene encoding estrogen receptor alpha (ESR1) was previously described

237 ear receptors (NRs) [androgen receptor (Ar), estrogen receptor alpha (Esr1), estrogen receptor beta (

238 n receptor (Ahr), interleukin-1 beta (Il1b), estrogen receptor alpha (Esr1), insulin like growth fact

239 ategies enabling neuron-specific deletion of estrogen receptor alpha (Esr1), we examine here whether

240 In rats, DES effects are mediated via Estrogen Receptor alpha (ESR1).

241 differentiation genes, mainly that encoding estrogen receptor alpha (Esr1/ERalpha).

242 ntromedial hypothalamus (VMHvl) that express estrogen receptor-alpha (Esr1) and progesterone receptor

243 Sustained expression of the estrogen receptor-alpha (ESR1) drives two-thirds of brea

244 coid receptor (GR/NR3C1) gene and one in the estrogen receptor-alpha (ESR1) gene were significant (q

245 Using wild-type (WT) and estrogen receptor-alpha (ESR1) knockout (KO) male mice,

246 etic studies highlight the potential role of estrogen receptor-alpha (ESR1) mutations, which show inc

247 5 orders of magnitude more sensitive, by an estrogen receptor alpha (EsRalpha)-dependent mechanism.

248 d the distribution of the androgen receptor, estrogen receptor alpha, estrogen receptor beta, and pro

249 i3 channels that selectively mediate SOCE in estrogen receptor alpha-expressing (ERalpha(+)) breast c

250 hat promotes BC progression independently of estrogen receptor alpha expression.

251 Deletion of estrogen receptor alpha from B cells did not alter B cel

252 intra-chromosomal gene fusion involving the estrogen receptor alpha gene ESR1, and another involving

253 leads to demethylation and activation of the estrogen receptor-alpha gene, sensitizing the tumor cell

254 morphisms in the glucocorticoid receptor and estrogen receptor-alpha genes may modify the association

255 hormone receptor family (androgen receptor, estrogen receptor alpha, glucocorticoid receptor, minera

256 The bioreporter contains mutated human estrogen receptor alpha (hERalpha), called bisphenol A-t

257 e, in the induction of priming, regulated by estrogen receptor alpha in the nociceptor of female rats

258 Moreover, high levels of estrogen receptor alpha in these tumors enhanced the gro

259 between STAT3 acetylation and methylation of estrogen receptor-alpha in melanoma, which predicts mela

260 tic variants across the ESR1 locus (encoding estrogen receptor alpha) in 118,816 subjects from three

261 Moreover, estrogen receptor alpha-ir colocalized with ERbeta-EGFP

262 Estrogen receptor alpha is known to up-regulate expressi

263 Estrogen receptor alpha is required for oviductal transp

264 ikewise, renal IRI was exacerbated in female estrogen receptor alpha-KO mice, while female mice recei

265 terically regulated Cas9 by insertion of the estrogen receptor-alpha ligand-binding domain.

266 uR1, depending on its activation by membrane estrogen receptor alpha (mERalpha; during diestrus) vers

267 nvasive cancers from controls were uniformly estrogen receptor alpha negative and undifferentiated, w

268 A7 is associated with the worst prognosis in estrogen receptor alpha-negative (ERalpha(-)) invasive b

269 risk subgroups, and was specific for HER2(+):estrogen receptor alpha-negative (ERalpha(-)) patients (

270 can cause DNA double-strand breaks (DSB) in estrogen receptor-alpha-negative breast cells and that B

271 Neither estrogen receptor alpha nor progesterone receptor were d

272 Estrogen receptor alpha-null (Eralpha-/-) mutant mice de

273 acts bound to 17beta-estradiol (E2)-liganded estrogen receptor-alpha on estrogen response elements (E

274 rine ILC2s was observed in mice deficient in estrogen receptor alpha or estrogen receptor beta.

275 .e., liver X receptor, farnesoid X receptor, estrogen receptor alpha, peroxisome proliferator-activat

276 estrogen receptor beta, with up to 20% being estrogen receptor alpha positive.

277 btained from 89 postmenopausal women who had estrogen receptor-alpha positive breast cancer and were

278 In estrogen receptor alpha-positive (ER(+)) breast cancer c

279 o a highly invasive mesenchymal phenotype in estrogen receptor alpha-positive (ERalpha(+)) breast can

280 old subunit in hPAFc, is highly expressed in estrogen receptor alpha-positive (ERalpha(+)) luminal br

281 und develop aggressive, highly aneuploid and estrogen receptor alpha-positive (ERalpha+) mammary aden

282 ndifferentiated, whereas well-differentiated estrogen receptor alpha-positive papillary invasive canc

283 is a well-tolerated, effective treatment for estrogen receptor-alpha-positive (ER+) breast cancer, bu

284 17q23 and 20q13 were frequently amplified in estrogen receptor-alpha-positive luminal breast cancer.

285 variables tested, including staining for the estrogen receptor alpha, progesterone receptor, and c-er

286 Basal-like tumors typically lack estrogen receptor-alpha, progesterone receptor and HER2/

287 Messenger RNA levels for estrogen receptor-alpha, progesterone receptor and smoot

288 TNBC does not express estrogen receptor-alpha, progesterone receptor, or the H

289 however, currently used biomarkers, such as, estrogen receptor-alpha/progesterone receptor (ERalpha/P

290 trate that EMBER confirms a role for the TFs estrogen receptor alpha, retinoic acid receptors alpha a

291 pDC innate functions through cell-intrinsic estrogen receptor alpha signaling, but did not exclude a

292 On the other hand, SORBS3 coactivated estrogen receptor alpha signaling, leading indirectly to

293 ymal transition in breast cancer through the estrogen receptor alpha/Slug axis and that it is a poten

294 extracellular signal-related kinase 1/2, and estrogen receptor alpha) that lead to acute cholestasis

295 get network, including GPER/GPR30 itself and estrogen receptor alpha, the plasma membrane Ca(2+)-ATPa

296 ear receptor coactivator that interacts with estrogen receptor alpha to modulate its activity.

297 Silencing ATG7 or BECN1 caused estrogen receptor-alpha to exit the nucleus at the time

298 This article reports that p53 and estrogen receptor alpha were activated in endometrial ti

299 vity genes primarily sense signaling through estrogen receptor alpha, whereas the resistance genes mo

300 s showed a physical association of Shp2 with estrogen receptor alpha, which is necessary for the syne