ライフサイエンスコーパス: estrogen receptor beta

1 mice deficient in estrogen receptor alpha or estrogen receptor beta.

2 xes containing retinoic X receptor alpha and estrogen receptor beta.

3 he TSU-PR1 cell line contains high levels of estrogen receptor beta.

4 nantiomer has a relatively high affinity for estrogen receptor beta.

5 Estrogen receptor beta 2 (ERbeta2), an ERbeta1 splice va

6 Estrogen receptor beta, a homologue to estrogen receptor

7 activity, prolactin effects, and aspects of estrogen receptor beta activity.

8 Benzopyran selective estrogen receptor beta agonist-1 (SERBA-1) shows potent,

9 Estradiol, and the specific estrogen receptor-beta agonist DPN, decreased current am

10 The estrogen receptor-beta agonist provided a comparable lev

11 WAY-202196, a nonsteroidal selective estrogen receptor-beta agonist, was tested in the murine

12 17-beta-Estradiol or estrogen receptor beta agonists dipropylnitrile and beta

13 New diphenolic azoles as highly selective estrogen receptor-beta agonists are reported.

14 (betaERKO(-/-)), estrogen receptor-alpha and estrogen receptor-beta (alphabetaERKO(-/-)), and GPER (G

15 e, estrogen receptor alpha (XbaI and PvuII), estrogen receptor beta (AluI), and estrogen receptor bet

16 ly through L- and R-type VGCCs by activating estrogen receptor beta and GPR30, respectively.

17 In situ hybridization for mRNA encoding estrogen receptor beta and progesterone receptor was car

18 leaflet were also found to express mRNA for estrogen receptor beta and progesterone receptor.

19 d fatty acid oxidation, are regulated by the estrogen receptor-beta and consequently contribute to ca

20 common variants in estrogen receptor-alpha, estrogen receptor-beta and the progesterone receptor pro

21 ii) 3beta-Diol is a pro-apoptotic ligand for estrogen receptor beta, and (iii) 3beta-tetrahydrosteroi

22 tifs have diverse affinities for the VDR and estrogen receptor beta, and mutation of specific motifs

23 androgen receptor, estrogen receptor alpha, estrogen receptor beta, and progesterone receptor mRNA a

24 in estrogen receptor-alpha (alphaERKO(-/-)), estrogen receptor-beta (betaERKO(-/-)), estrogen recepto

25 Expression of the estrogen receptor beta by CD4(+) T cells was necessary f

26 d PvuII), estrogen receptor beta (AluI), and estrogen receptor beta(cx) (Tsp509I), endothelial nitric

27 to isoflavones and to placebo was found with estrogen receptor beta(cx) Tsp509I genotype AA, but not

28 ), estrogen receptor-alpha (EC50 17 nM), and estrogen receptor-beta (EC50 27.5 nM), while the corresp

29 estrogen receptor-alpha (EC50 58.7 nM), and estrogen receptor-beta (EC50 78.5 nM).

30 The discovery of estrogen receptor beta (ER beta) and subsequent localiza

31 n of the estrogen receptor alpha (ER alpha), estrogen receptor beta (ER beta), progesterone receptor

32 and in vitro models to determine the role of estrogen receptor beta (ER-beta) and its ligands on adip

33 Estrogen receptor beta (ER-beta) and its selective ligan

34 Estrogen receptor beta (ER-beta) regulates diverse physi

35 nd to estrogen receptor alpha (ER-alpha) and estrogen receptor beta (ER-beta), and antagonize the act

36 black cohosh to the ligand binding domain of estrogen receptor beta (ER-beta).

37 that express the more recently characterized estrogen receptor-beta (ER-beta) has not been examined i

38 It has been shown that the activation of estrogen receptor-beta (ER-beta) plays an important card

39 oughly characterized for its specificity for estrogen receptor-beta (ER-beta), was used to immunoloca

40 DNF, estrogen receptor-alpha (ER-alpha), and estrogen receptor-beta (ER-beta), we found only sparse c

41 e we describe the generation of mice lacking estrogen receptor beta (ERbeta -/-) by insertion of a ne

42 This effect is mediated by estrogen receptor beta (ERbeta) acting as a monomer, whe

43 Estrogen receptor beta (ERbeta) activates transcription

44 In particular, estrogen receptor beta (ERbeta) agonists have been shown

45 ncurrently to a data set of highly selective estrogen receptor beta (ERbeta) agonists.

46 Estrogen receptor beta (ERbeta) and androgen receptor (A

47 IMP3 expression is repressed specifically by estrogen receptor beta (ERbeta) and its ligand 3betaA-di

48 The two receptors are estrogen receptor beta (ERbeta) and liver X receptor bet

49 TAM engaged mitochondrial estrogen receptor beta (ERbeta) as an antagonist in MCF7

50 -length estrogen receptor alpha (ERalpha) or estrogen receptor beta (ERbeta) bound to a fluorescein-l

51 Activation of estrogen receptor beta (ERbeta) but not ERalpha rescued

52 the transcription factors DLX5 and EGR3 and estrogen receptor beta (ERbeta) directly controlling its

53 The current study examined whether estrogen receptor beta (ERbeta) expression in spine syna

54 Loss of estrogen receptor beta (ERbeta) expression in the gut is

55 Little is known about endogenous estrogen receptor beta (ERbeta) gene targets in human br

56 in vivo from the hearts of wild-type but not estrogen receptor beta (ERbeta) gene-deleted mice admini

57 Estrogen receptor beta (ERbeta) has potent antiprolifera

58 Although the distribution of estrogen receptor beta (ERbeta) immunoreactivity in the

59 sion of estrogen receptor alpha (ERalpha) or estrogen receptor beta (ERbeta) in the hippocampus of ag

60 ion of estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta) in the mouse cortex duri

61 t, selective binding and agonist function in estrogen receptor beta (ERbeta) in vitro assays.

62 Estrogen receptor beta (ERbeta) is activated in the pros

63 Estrogen receptor beta (ERbeta) is emerging as a critica

64 The estrogen receptor beta (ERbeta) is emerging as an import

65 Estrogen receptor beta (ERbeta) is essential for migrati

66 Estrogen receptor beta (ERbeta) is expressed in cortical

67 By contrast, estrogen receptor beta (ERbeta) is expressed in many bra

68 rian granulosa cells, we discovered that the estrogen receptor beta (ERbeta) is inducible by activin.

69 In lung adenocarcinoma cells, the estrogen receptor beta (ERbeta) is the predominating for

70 In 1998, an estrogen receptor beta (ERbeta) knockout (KO) mouse was

71 use dihydrotestosterone is the precursor for estrogen receptor beta (ERbeta) ligands, 5AR inhibitors

72 f midbrain DA neurons are immunopositive for estrogen receptor beta (ERbeta) or androgen receptors (A

73 In the brain, estrogen receptor beta (ERbeta) plays important roles in

74 Estrogen receptor beta (ERbeta) promotes the degradation

75 eloped that selectively bind to and activate estrogen receptor beta (ERbeta) rather than estrogen rec

76 This regulation involves Estrogen Receptor beta (ERbeta) recruitment to the Elect

77 Estrogen receptor beta (ERbeta) selective agonists are c

78 of Blood, Yakimchuk and colleagues show that estrogen receptor beta (ERbeta) signaling can act tumor-

79 eviously reported that antiestrogen-liganded estrogen receptor beta (ERbeta) transcriptionally activa

80 eviously reported that antiestrogen-liganded estrogen receptor beta (ERbeta) transcriptionally activa

81 for the localization of the newly identified estrogen receptor beta (ERbeta) within the rat paraventr

82 ptors (estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta)) that bind 17beta-estrad

83 Estrogen receptor beta (ERbeta), a less active ER subtyp

84 Moreover, siRNA-mediated knockdown of estrogen receptor beta (ERbeta), but not ERalpha, abolis

85 eceptors, estrogen receptor alpha (ERalpha), estrogen receptor beta (ERbeta), or the G protein-couple

86 This effect is mediated by estrogen receptor beta (ERbeta), which directly associat

87 Estrogen effects are mediated by estrogen receptor beta (ERbeta), which reduces chromatin

88 r smooth muscle cells and blood vessels from estrogen receptor beta (ERbeta)-deficient mice exhibit m

89 Activation of estrogen receptor beta (ERbeta)-expressing neurons regul

90 We have previously shown that estrogen receptor beta (ERbeta)-mediated up-regulation o

91 Diarylpropionitrile (DPN), an estrogen receptor beta (ERbeta)-specific agonist, and to

92 ish estrogen receptor with homology to human estrogen receptor beta (ERbeta).

93 learning and memory via the newly discovered estrogen receptor beta (ERbeta).

94 interacted with the ligand-binding domain of estrogen receptor beta (ERbeta).

95 ha (ERalpha) and as a complete antagonist on estrogen receptor beta (ERbeta).

96 ene expression through an effect mediated by estrogen receptor beta (ERbeta).

97 ptors, estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta).

98 nd for estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta).

99 y demonstrated mitochondrial localization of estrogen receptor beta (ERbeta).

100 pothesis that defeminization is regulated by estrogen receptor beta (ERbeta).

101 ymphoma is repressed following activation of estrogen receptor beta (ERbeta, ESR2).

102 over, pharmacologic inhibition of microglial estrogen receptor-beta (ERbeta) function corrects the re

103 These mice express the newly described estrogen receptor-beta (ERbeta) in their aortas, suggest

104 structure-based optimization of a series of estrogen receptor-beta (ERbeta) selective ligands.

105 Estrogen receptor-alpha (ERalpha), estrogen receptor-beta (ERbeta), and progestin receptor

106 al of this study was to determine whether an estrogen receptor-beta (ERbeta)-selective agonist (GTx-8

107 ptors, estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta).

108 cta (SNpc) DA neurons are immunoreactive for estrogen receptor-beta (ERbeta).

109 ptors [estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta)] to promote changes in p

110 s [estrogen receptor alpha (XbaI and PvuII), estrogen receptor beta [ERbeta (AluI) and ERbeta[cx] (Ts

111 Estrogen receptors beta (ERbetas) are present in PVN neu

112 ation by steroid receptors, and we show that estrogen receptor beta (ESR2) is the main vector of estr

113 Fluoxetine and EE2 alone did not affect estrogen receptor beta (esr2), but the co-exposure down

114 ceptor (Ar), estrogen receptor alpha (Esr1), estrogen receptor beta (Esr2), glucocorticoid receptor (

115 rough estrogen receptor alpha (ESR1) but not estrogen receptor beta (ESR2).

116 alignancies according to tumor expression of estrogen receptor-beta (ESR2).

117 the hypothesis that sequence variants of the estrogen receptor beta gene (ESR2) may be associated wit

118 gnition and psychological resources, and the estrogen receptor beta gene (ESR2) polymorphism rs297838

119 women but may increase HDL cholesterol in an estrogen receptor beta gene-polymorphic subgroup.

120 The novel estrogen receptor beta has also been detected in lung tu

121 Although specific effects mediated by estrogen receptor beta in vivo remain to be elucidated,

122 ch interact with estrogen receptor-alpha and estrogen receptor-beta in multiple tissues, continue to

123 Pharmacologic activation of estrogen receptor beta increases mitochondrial function,

124 found that the vitamin D receptor (VDR) and estrogen receptor beta interact with different alpha-hel

125 sexual motivation through the activation of estrogen receptor beta interacting with the metabotropic

126 Here, we report that estrogen receptor beta is alternatively modified by eith

127 S-equol has a high affinity for estrogen receptor beta (K(i) = 0.73 nmol/L), whereas R-e

128 ast to ERalphaKO mice, IA performance by OVX estrogen receptor-beta-knockout (ERbetaKO) mice was not

129 nge (HDX) mass spectrometry in analyzing the estrogen receptor beta ligand binding domain (ERbeta LBD

130 taining revealed estrogen receptor-alpha and estrogen receptor-beta localized in the nucleus and cyto

131 overy of a second estrogen receptor subtype, estrogen receptor-beta, may significantly advance our un

132 anslated protein first suggested that murine estrogen receptor beta (mER-beta) is O-GlcNAcylated.

133 Recently, we demonstrated that the murine estrogen receptor-beta (mER-beta) is alternatively O-Glc

134 Expression of estrogen receptor-alpha and estrogen receptor-beta mRNA in lumbar spinal cord was sh

135 ith sulforaphane and diarylpropionitrile, an estrogen receptor beta selective agonist, results in NRF

136 ent with the hypothesis of a joint effect of estrogen receptor beta sequence variants and endogenous

137 BPS on myocyte Ca2+ handling was mediated by estrogen receptor beta signaling and by rapid increases

138 We propose that E2, acting through estrogen receptor-beta, transactivates synaptic TrkB and

139 modifications may play a role in regulating estrogen receptor beta transactivation and turnover.

140 Expression of estrogen receptor beta was increased in lesions compared

141 suming soy foods, has selective affinity for estrogen receptor-beta, whereas both enantiomers modulat

142 rogen receptors (estrogen receptor-alpha and estrogen receptor-beta), which bind to DNA and function

143 d from women and mice are immunopositive for estrogen receptor beta, with up to 20% being estrogen re