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1 lic precursor of 8-prenylnaringenin, was not estrogenic.
2 ing that a proportion of RA effects are anti-estrogenic.
5 an uterine (Ishikawa) cells to determine the estrogenic action of D3 on the activation and nuclear tr
6 was found to maintain bone density of rats (estrogenic action) while simultaneously preventing mamma
8 brain testosterone plays both androgenic and estrogenic actions due to its conversion into estrogen v
9 elated differences in estrogen receptors and estrogenic actions in the brain are discussed, with the
10 a physiologically relevant role in mediating estrogenic actions on energy expenditure in females.
12 s via ERalpha, licorice might have different estrogenic activities due to its ERbeta selectivity, par
14 key and novel mechanistic differences in the estrogenic activities of BEs vs. E2, with BEs displaying
17 of liquiritigenin, demonstrated significant estrogenic activities while xanthohumol, a metabolic pre
18 nts of liquiritigenin have various levels of estrogenic activities, suggesting the importance of prec
22 stances found in food contact materials with estrogenic activity (EA) have created substantial demand
23 ns observed in surface waters failed to show estrogenic activity (induction of vitelloginin mRNA).
25 ding to goldfish testis androgen receptors), estrogenic activity (yeast estrogen screen), and neurotr
28 l incorporated into plastics and resins, has estrogenic activity and is associated with adverse healt
31 he E-isomers of FR 4OHT and endoxifen had no estrogenic activity at therapeutic serum concentrations.
32 n of parent compounds into degradates having estrogenic activity can explain their environmental pers
33 studies, fractions of groundwater with high estrogenic activity contained hetero-PAHs and their hydr
35 as also paid to monitoring of changes in the estrogenic activity during these particular in vitro exp
38 selected hetero-PAHs were screened for their estrogenic activity in lyticase yeast estrogen screen (L
39 ated against 17beta-estradiol (E2) for their estrogenic activity in MCF-7 human breast cancer cells.
41 decreased estrogen deprivation and increased estrogenic activity in the liver, whereas such benefit w
46 levant concentrations may be associated with estrogenic activity measured in water extracts and feral
47 ble to 1 in primary neurons, confirming that estrogenic activity of 1 in neurons is not a unique phen
53 bioassay using T47D-KBluc cells showed that estrogenic activity of receiving water near the outflow
54 In an effort to further characterize the estrogenic activity of TCDD, a comprehensive time-course
55 lvement of Wnt/beta-catenin signaling in the estrogenic activity of this diarylheptanoid in transfect
57 y has also been documented in the removal of estrogenic activity that correlated with the EE2 degrada
58 t, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha
59 icate that TCDD may also elicit AhR-mediated estrogenic activity through interactions with the estrog
61 ions, had no hormone-like activities whereas estrogenic activity was found in the filtered tap water.
64 ion of steroid hormones, phytoestrogens, and estrogenic activity was thoroughly characterized within
65 To verify this effect was caused by reduced estrogenic activity we confirmed that in hypoxic mice in
66 ural steroid hormones and phytoestrogens and estrogenic activity were assessed across the lagoon/spra
67 ninolytic enzymes were found to decrease the estrogenic activity with EE2 removal proportionally.
69 In females, uterine mass (an indicator of estrogenic activity) was also greatest on high P:C diets
70 ding, the O(1)...O(2) distance necessary for estrogenic activity, and the electrostatic potential fea
71 ls in the environment, especially those with estrogenic activity, are able to disrupt the programming
72 BPA), an environmental contaminant with weak estrogenic activity, resists microbial degradation under
86 ivating molecular mechanisms associated with estrogenic agonist activity in rat primary hippocampal n
90 k which has spurred research into developing estrogenic alternatives that have the beneficial effects
92 hemicals with potential to interact with the estrogenic and androgenic pathways, and could help prior
93 and transcriptional-reporter gene assays for estrogenic and anti-androgenic activity were performed o
94 costatic properties, including possible anti-estrogenic and anti-aromatase activity, and seems to be
98 Isoflavones, plant-derived compounds with estrogenic and antioxidant properties, may offer immunol
100 mass spectrometry (negative ion) of selected estrogenic and nonestrogenic fractions identified compou
101 arbonate plastic and epoxy resins, is weakly estrogenic and therefore of environmental and human heal
103 ally to downstream steroid hormones leads to estrogenic and/or androgenic effects which may be import
104 Bisphenol-A (BPA) has been shown to modulate estrogenic, androgenic, and anti-androgenic effects.
107 Untreated wastewater induced antiandrogenic, estrogenic, antiestrogenic, and retinoid-like activity.
108 r of magnitude and of similar action as BPA (estrogenic, antiestrogenic, androgenic, and antiandrogen
109 ted biphenyls (PCBs) have been shown to have estrogenic, antiestrogenic, or antiandrogenic properties
110 d (Z-BDDA) is a seco-steroid that has potent estrogenic as well as antioxidant activities in vitro an
114 gest new targets for abnormal programming by estrogenic chemicals and provide evidence supporting the
115 oreporter was characterized with mixtures of estrogenic chemicals and tested with spiked influent was
116 tes that the in vitro effects of mixtures of estrogenic chemicals can be well predicted from the estr
117 helium during fetal life by small amounts of estrogenic chemicals could permanently disrupt cellular
118 orescence responses for a range of different estrogenic chemicals in the new transgenic zebrafish mod
120 the effects of mixtures composed of up to 17 estrogenic chemicals were examined using estrogenicity a
122 nd highly integrative system for identifying estrogenic chemicals, their target tissues and effect co
127 estrogen receptor by reducing levels of the estrogenic cholesterol metabolite 27-hydroxycholesterol.
128 ng effect directed analysis, the presence of estrogenic components in untreated and biologically trea
130 er electronics likely constitute a source of estrogenic compound contamination in the indoor environm
132 antiandrogenic compound) or methoxychlor (an estrogenic compound) induced an adult phenotype in the F
134 aordinary reliability in identifying diverse estrogenic compounds and in differentiating between thei
136 of Opportunity" theory, which suggests that estrogenic compounds can exert positive effects on verba
145 ma has been shown to interact with synthetic estrogenic compounds such as 4-hydroxytamoxifen (4-OHT),
146 ines of research suggest that estrogens (and estrogenic compounds) are neuroprotective following expe
147 effects and at cytotoxic levels of analyzed estrogenic compounds, which is not possible with the cla
154 e pathology, including excessive exposure to estrogenic compounds; however, the molecular basis for t
156 Whereas most attention has been focused on estrogenic congeners, we tested the cancer-inducing pote
158 f HRP-mediated reactions in the treatment of estrogenic contaminants, and they constitute an importan
159 Furthermore, by 2050 a moderate increase in estrogenic contamination and the potential risk to wildl
160 eatic responses to MI-TP, and androgenic and estrogenic contributions to such responses (direct fetal
161 osynthesis of choline and this gene is under estrogenic control, we hypothesized that there are SNPs
162 similar dose (0.1 microg/kg per day) of the estrogenic drug diethylstilbestrol (DES), a known human
163 tant increase in temperature and exposure to estrogenic EDCs on reproduction and development in an es
171 tion has important implications on long term estrogenic effects affecting smooth muscle and neural fu
174 corice extracts; however, it exhibited lower estrogenic effects compared to 8-prenylnaringenin in fun
178 of E2 in breast cancer therapy but minimizes estrogenic effects in other tissues is a novel, therapeu
180 regulatory role for RIP140 in mediating anti-estrogenic effects of RA in estrogen-dependent breast ca
183 current study was to evaluate the potential estrogenic effects of three licorice species (Glycyrrhiz
184 level is significantly reduced and that the estrogenic effects on apoA-IV gene expression and food i
185 enistein, a major component of soy, has weak estrogenic effects on breast epithelium, and has been fo
186 This was consistent with identification of estrogenic effects on gene expression, high BPA exposure
187 nd neuroanatomical studies that suggest that estrogenic effects on song processing might be mediated
188 eated female zebra finches to investigate if estrogenic effects on song responsiveness are mediated v
190 igh antiandrogenic and minor dioxin-like and estrogenic effects persisted in the treated effluent tha
191 terine myometrium, in contrast to apparently estrogenic effects previously found in the breast of Sev
192 se BPA alternatives induce similar toxic and estrogenic effects to BPA and that BPAF is more potent t
193 Both estrogens and smoking, with known anti-estrogenic effects, alter the atherogenic lipid profile.
194 ollutants and pathogens and the reduction of estrogenic effects, whereas the in vitro mutagenicity in
197 contraceptive adjuvant, the impact of these estrogenic endocrine disrupting chemicals (EDCs) on the
198 xpression is also increased upon exposure to estrogenic endocrine disrupting chemicals (EDCs) such as
199 onmental factors, such as antiandrogenic and estrogenic endocrine disrupting chemicals (EDCs), are su
206 reduced by APV and Rp-cAMPS, suggesting that estrogenic enhancement of object memory involves NMDA re
208 ata on predisposing factors related to race, estrogenic exposure, cryptorchidism, and infertility are
209 ns of singular steroidal estrogens or to the estrogenic extract of an anaerobic swine waste lagoon.
210 r important new insights into the ability of estrogenic GPER signaling to trigger HIF1alpha-dependent
211 ility of experiments as shown by morphology, estrogenic growth dose-response, whole genome gene expre
212 Brca1 loss in mammary epithelium alters the estrogenic growth response and that exposure to increase
214 ion kinetics and mechanisms of three natural estrogenic hormones (17alpha-estradiol, 17beta-estradiol
223 were exposed to environmental levels of the estrogenic insecticide bifenthrin or ethinylestradiol (E
226 p,p -DDE with development in response to its estrogenic isomer, o,p -DDE [1,1-dichloro-2-(o-chlorophe
227 folding-biosensor is useful in evaluation of estrogenic ligands and their downstream effects, and in
228 ort here that 1 can be transformed into anti-estrogenic ligands by simple alkyl substitutions of the
229 ellogenin/choriogenin induction by different estrogenic ligands correlated positively with preferenti
230 rs in vivo and to distinguish the ability of estrogenic ligands to promote ER homo- vs. heterodimeriz
232 nd suburban ponds may be contributing to the estrogenic load within suburban freshwaters and constitu
233 ish embryo-larvae and an assessment on their estrogenic mechanisms in an estrogen-responsive transgen
235 though multiple studies have concentrated on estrogenic mechanisms of disease modulation, fairly litt
236 unction, the molecular mechanisms underlying estrogenic memory modulation remain largely unknown.
237 ly (P=0.03) lower ratios of nonestrogenic to estrogenic metabolites (2-hydroxyestrone 1/16 alpha-hydr
238 potently stimulated by estradiol as well as estrogenic metabolites of 5alpha-dihydrotestosterone.
239 e of male sexual motivation are activated by estrogenic metabolites of testosterone (T) in a fast man
240 rmethrin, biotransformation of bifenthrin to estrogenic metabolites was not observed in medaka liver
244 induce any toxic effects (cyto-genotoxicity, estrogenic or anti-androgenic activity) in vitro at rele
245 hormonal therapies to exert tissue-specific estrogenic or antiestrogenic activities, this knowledge
246 any EDCs studied thus far in fish have known estrogenic or antiestrogenic effects, and as such cause
247 iphenyltrichloroethane (DDT) is a persistent estrogenic organochlorine pesticide that is a rodent hep
248 drive biomarker induction in fish exposed to estrogenic pollutants and provide a case study on the ca
250 as these products were shown to have a lower estrogenic potency but are expected to have a higher bio
253 revealed augmented SSFs reduced the overall estrogenic potency of the supplied water by 25% on avera
257 es involved in these pathways have different estrogenic potentials, as implied by our analysis of the
259 ved compounds found mainly in soy with known estrogenic properties and a potential for benefits to hu
263 (BPA), an endocrine-disrupting compound with estrogenic properties, fed to a/a dams harboring A(vy)/a
266 e report here a remarkable sex difference in estrogenic regulation of neuronal activity in male vs. f
267 provide data that support the importance of estrogenic regulation of S6K1 expression in breast cance
268 al prefrontal cortex (mPFC), suggesting that estrogenic regulation of the DH influences mPFC spinogen
270 ion, mERalpha signaling is important for the estrogenic response in female mice in a tissue-dependent
271 types are critically involved in the teleost estrogenic response, with the ERalpha:ERbeta ratio being
272 a large set of ER data, accurately predicted estrogenic responses and demonstrated its utility for ch
273 NA binding and ER coactivator, in amplifying estrogenic responses and promoting breast cancer tumorig
277 exposure activity ratios for biological and estrogenic responses, known chemical:gene interactions f
280 compounds that were uniquely present in the estrogenic samples, biologically treated and untreated.
281 ess water (OSPW) was detected with the yeast estrogenic screening assay after fractionation with soli
282 The hypothesis is that in normal tissue the estrogenic SERM activity of a dual AI/SERM could attenua
283 lts indicate that Beclin 1 can down-regulate estrogenic signaling and growth response, and contribute
284 otein-coupled receptor GPR30 (GPER) mediates estrogenic signaling in breast cancer cells and cancer-a
285 microdialysis were used to determine whether estrogenic signaling in the mPOA modulates cocaine-induc
286 g chemicals (EDCs) are suspected of altering estrogenic signaling through estrogen receptor (ER) alph
287 tively, these data demonstrate that aberrant estrogenic signaling through the K303R ERalpha mutation
288 one quality are due to either stimulation of estrogenic signaling via isoflavones or through a novel
290 cular mechanisms by which antiandrogenic and estrogenic signals induce penile malformations and demon
295 anium dioxide (nTiO2) for rapid detection of estrogenic substance (bisphenol A) has been proposed.
297 The sensitive response of this biosensor to estrogenic substances results from changes in the struct
299 llary study was designed to assess potential estrogenic treatment effects on cognition and mood.
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