ライフサイエンスコーパス: ethical

1 lethal, studies on human volunteers are not ethical.

2 search for reasons ranging from practical to ethical.

3 oute of vaccination is neither practical nor ethical.

4 their attitudes about participation and its ethical acceptability, medical oncologists affiliated wi

5 become less clear and vivid than memories of ethical actions or other types of actions that are eithe

6 variation also undercuts the SWCT's expected ethical advantages over the RCT, because an RCT, but not

7 atively little attention, and there is scant ethical analysis and guidance available to decision make

8 tient with incurable cancer and conducted an ethical analysis incorporating (1) evidence from both We

9 Our study provides evidence to guide ethical analysis of issues in psychiatric research, and

10 In this article, we provide a systematic ethical analysis of the family overrule of donation of s

11 Surgeons are facing increasingly difficult ethical and clinical decisions given the rapidly expandi

12 ensitivity of policy trade-offs to different ethical and empirical assumptions, they are increasingly

13 d of innovation by overcoming technological, ethical and financial challenges.

14 Equally important will be the ethical and interpretable return of results to practicin

15 ) psychopathology, (4) social resources, (5) ethical and legal factors, and (6) information and risk

16 legal duties of study participants have both ethical and legal implications for researchers.

17 f personal privacy and may have far-reaching ethical and legal implications.

18 onal, interdisciplinary symposium focused on ethical and legal issues in transplantation.

19 Despite ethical and legal obligations to disclose findings promp

20 cations for organ procurement, whether it is ethical and legal to "maim" a living individual for the

21 pilot studies to assess the feasibility and ethical and logistical considerations related to the dev

22 creened donor stool when needed, without the ethical and logistical problems associated with patient-

23 es, the subjects addressed encompass complex ethical and medico-legal aspects of patient care that af

24 Due to blood volume requirements as well as ethical and practical considerations, the study was limi

25 Pain management in opioid abusers engenders ethical and practical difficulties for clinicians, often

26 uth-telling, and we considered the published ethical and practice guidance, as well as the perspectiv

27 nities and are generally aggregated for both ethical and pragmatic reasons that may further obscure t

28 Research was formed to identify and address ethical and regulatory challenges associated with the re

29 Consequently, development of ethical and regulatory frameworks that ensure their safe

30 Partly because of improvements to ethical and regulatory guidance, human challenge studies

31 Importantly for ethical and safety reasons, the drivers for this increas

32 ly, the isolation of human fetal NCC carries ethical and scientific challenges, as NCC induction typi

33 Both ethical and scientific justifications exist for integrat

34 idelines have been constructed to provide an ethical and scientific quality standard for trials that

35 earning during undergraduate research, makes ethical and societal impacts of science clear by relatin

36 s, the HPTN 071 (PopART) Study Team consider ethical and study power concerns and the importance of t

37 However, ethical and technical challenges have hampered the ident

38 ative understanding of which lies beyond the ethical and technical reach permitted by animal studies.

39 help individuals and organizations maintain ethical and transparent publication practices and comply

40 on a collaborative basis, it makes economic, ethical, and academic sense to explore the option to uti

41 discontinuation has significant scientific, ethical, and economic implications.

42 inary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure res

43 health professionals who have the clinical, ethical, and human competencies necessary for the provis

44 uman embryos, which raises a host of social, ethical, and legal questions.

45 rials in pregnancy raise several scientific, ethical, and logistic challenges, which are compounded f

46 nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to pe

47 case and learning guide for the scientific, ethical, and regulatory challenges of future reproductiv

48 ate challenges and solutions to operational, ethical, and regulatory issues.

49 iety unprepared to deal with the scientific, ethical, and societal implications of a surgical procedu

50 g this population and offer a roadmap for an ethical approach to conducting research on individuals w

51 han merely cost savings-again depends on the ethical approach to valuing population.

52 ds may pose a slight challenge to this novel ethical approach.

53 and were eligible for pooling given adequate ethical approval and availability of essential variables

54 Materials and Methods After ethical approval and patient informed consent were obtai

55 stmortem human donor eyes were obtained with ethical approval and processed for calretinin immunofluo

56 0 subjects) were tested for eight NAbs after ethical approval and signed consents.

57 placental biomarkers with US, performed with ethical approval and written informed consent.

58 Materials and Methods Ethical approval for the study was obtained from the eth

59 The institutional review board waived ethical approval for this retrospective review, in which

60 Ethical approval was granted in each of the participatin

61 Materials and Methods Ethical approval was obtained for this retrospective, HI

62 Ethical approval was obtained from Boston Children's Hos

63 Materials and Methods Ethical approval was obtained, and participants provided

64 Patient consent and ethical approval were obtained for this study.

65 goal of 708 participants, but due to delayed ethical approval, only 623 women were recruited at 24 we

66 ren's Hospital in Columbus, OH, USA, granted ethical approval.

67 Beyond the ethical argument in support of this approach, decision a

68 re success of data sharing and highlight the ethical argument that data sharing may be necessary to m

69 However, the ACP believes that the ethical arguments against legalizing physician-assisted

70 rovide answers to controversial and delicate ethical as well as clinical problems.

71 e information on the medical, financial, and ethical aspects of the procedure.

72 efinition and historical, social, legal, and ethical aspects; (2) the view from different disciplines

73 he study proposes a possible roadmap for the ethical assessment of sham surgery clinical trials (CTs)

74 ality of results, providing that an accurate ethical assessment procedure is in place, firstly to ens

75 Here, I call attention to these ethical barbs and suggest a way in which to proceed caut

76 4948 , registered June 14, 2013; Institution Ethical Board Approval: KEK-ZH-Nr.

77 d their discussions have helped to shape the ethical boundaries of organ transplantation today.

78 emptation to act unethically, we often cross ethical boundaries.

79 legal demands, and to reassess longstanding ethical certainties in the strictest view of promoting s

80 can play in this transformation, which poses ethical challenges and obstacles.

81 dations and guidelines for the management of ethical challenges encountered by donation physicians.

82 organ donation, but incurs psychosocial and ethical challenges for recipients because of the risks i

83 forded by treatment as prevention, important ethical challenges must be addressed, including those re

84 al HIV-positive donors, there are additional ethical challenges of privacy, fairness, and the right t

85 ms, however, raise a number of practical and ethical challenges that need to be worked through and re

86 ticipation of actual, potential or perceived ethical challenges with the role, Canadian Blood Service

87 n, we consider the technical, practical, and ethical challenges with the use of spatial big data in i

88 Modern medical care has also resulted in new ethical challenges, for example, those related to deacti

89 Deceased donation medicine involves unique ethical challenges.

90 ic health emergencies and disasters may pose ethical challenges.

91 RIAL/METHODS: After obtaining permission and ethical clearance from concerned authorities, an anonymo

92 MATERIAL/After ethical clearance, 79 treatment naive patients with head

93 sent is to secure consent and donation, some ethical commentary on requesting consent emphasizes that

94 he retrospective character of the study, the ethical committee did not require any written informed c

95 and Methods Approval from the institutional ethical committee for animal care and research ethics wa

96 execution of this study was approved by the Ethical Committee of Institute for Research in Maternal

97 The trial protocol was approved by the Local Ethical Committee of the Kirikkale University, date of r

98 The study was approved by the ethical committee of the University of Heidelberg.

99 its observational nature, approval from the ethical committee was not deemed necessary.

100 study was approved by the National Research Ethical Committee, and written informed consent was obta

101 Methods This study was approved by the local ethical committee, and written informed consent was obta

102 This study was approved by the local ethical committee, and written informed consent was obta

103 prospective study was approved by the local ethical committee.

104 y protocol was approved by the institutional ethical committee.

105 This study was approved by the local medical ethical committees of the Maastricht University Medical

106 This study was approved by the local ethical committees on human studies, and written informe

107 This study was approved by the local ethical committees on human studies, and written informe

108 Drawing from current ethical, conceptual, and empirical studies of objectivit

109 enefits (e.g. increased resident freedom) or ethical concerns (e.g. resident privacy); 2.

110 This difference has generated ethical concerns about the exposure of otherwise young a

111 owever, these lines of research raise thorny ethical concerns about the moral status of such chimeric

112 Potential practical and ethical concerns about the use of extraterritorial juris

113 However, there are ethical concerns about the use of such technologies, and

114 Given ethical concerns and costs associated with non-human pri

115 feasible to conduct such a trial because of ethical concerns or budgetary constraints.

116 ad are enormous, such as genome editing, but ethical concerns persist.

117 ma formation or in vitro differentiation, as ethical concerns preclude generation of human-human or h

118 ood disorders and to provide data to address ethical concerns regarding research in this population.

119 -infected mosquitoes, in part because of the ethical concerns related to exposing a human subject's a

120 Although safety and ethical concerns remain, we call for the acceleration of

121 Ethical concerns surround the use of e-cigarettes among

122 guidance, resources, and practical advice on ethical concerns that arise in academic publishing for e

123 The kinds of ethical concerns that seem to underlie this research and

124 ) research and clinical practice have raised ethical concerns worldwide.

125 eristics, stockpile management, funding, and ethical concerns, such as equity.

126 n experiential learning, and this has raised ethical concerns.

127 disorders, but it may also raise substantial ethical concerns.

128 laborious and time-consuming procedures, and ethical concerns.

129 induce immunological rejection and generate ethical concerns.

130 P) accumulated substantial experience in the ethical conduct of research to the highest standards.

131 Guidelines for safe and ethical conduct of such procedures have previously and i

132 ts' legal duties and the resulting legal and ethical consequences for researchers.

133 The following exploration of these various ethical considerations demonstrates that the language of

134 mately, appropriate responses to the various ethical considerations explored here must vary based on

135 er and Dominic Kwiatkowski discuss important ethical considerations for sustainable genomics research

136 eliable primate model for HCV infection, but ethical considerations have restricted their utility in

137 We present a review and analysis of the ethical considerations in off-label ketamine use for sev

138 Emerging ethical considerations include mandatory vaccination and

139 The analysis of ethical considerations is contextualised in an overview

140 tient, but clinicians believe that competing ethical considerations justify not providing them.

141 common types; highlight the pros, cons, and ethical considerations of these designs; and illustrate

142 ses of human disease, although practical and ethical considerations preclude their demonstration to t

143 Current ethical considerations related to tuberculosis preventio

144 gh chimeric research, as well as fundamental ethical considerations such as those concerning the prov

145 ween molecular and epidemiological data, and ethical considerations with respect to infectious-diseas

146 This review addresses these ethical considerations, including issues surrounding inf

147 ent clinical trials of DBS for SZ, and their ethical considerations.

148 control group, which was not included due to ethical considerations; clinical study requirements impo

149 l types for clinical application without any ethical controversy arising from the use of embryonic st

150 There remains much scientific, clinical, and ethical controversy concerning the use of electroconvuls

151 the morning or evening: the matrix task (an ethical decision task) and the balloon analog risk task

152 wn research projects, and develops students' ethical decision-making skills.

153 most aspects of society, and scientists face ethical decisions as a routine part of their work, but s

154 increased parental advocacy, physicians face ethical decisions in formulating recommendations includi

155 sent knowledge about normative and empirical ethical demands in this setting is quantified and summar

156 Despite the technical and ethical demands of experimental chimeras, including huma

157 ure search using MEDLINE, we report the main ethical developments in paediatric oncology clinical tri

158 the timing of vaccines, which often poses an ethical dilemma for physicians.

159 This review addresses an ethical dilemma in the context of complex clinical medic

160 iving kidney donor transplantation; however, ethical dilemmas and concerns for the donor instilled am

161 Ethical dilemmas and conflicts are inherent in today's h

162 of the respondents reported they experience ethical dilemmas and conflicts from several times a mont

163 though it may be impossible to eliminate all ethical dilemmas and conflicts, leaders and organization

164 l distress and moral voice: (a) frequency of ethical dilemmas and conflicts; (b) moral efficacy; (c)

165 mutation carrier status, could pose specific ethical dilemmas in the design of these trials.

166 lacement therapy poses several practical and ethical dilemmas of global relevance for patients, clini

167 that may influence staff's decisions on the ethical dilemmas raised by dementia.

168 Advances in neurotechnology will raise new ethical dilemmas, to which scientists and the rest of so

169 o evaluate scholarly research addressing the ethical dimensions of penile transplantation.

170 ed by partial regulatory frameworks, intense ethical discussions, and meaningful changes in social be

171 nvoluntary medical repatriation violates the ethical duties of health care providers.

172 asons for this trend are health concerns and ethical, ecologic, and social issues.

173 oral efficacy; (c) ethics communication; (d) ethical environment; and (e) organizational ethics suppo

174 We provide an ethical framework to guide transplant stakeholders in us

175 Differences in culture, practice, ethical frameworks, research experience, and resource av

176 ions, including the introduction of explicit ethical frameworks, the enhanced attention to financial

177 We first identified the ethical goals that are promoted by obtaining consent for

178 good donors; 26% received information about ethical guidelines for soliciting donations from their p

179 Currently, no national ethical guidelines have been developed in the United Sta

180 research, ensuring that it conformed to the ethical guidelines of the 1975 Declaration of Helsinki.

181 coping and one related to following Islamic ethical guidelines, were not associated with organ donat

182 d thus provides a possible resolution to the ethical impasse in climate change economics.

183 There is an ethical imperative to generate evidence at an early stag

184 ased identifiability-a result with important ethical implications for microbiome study design.

185 ts on personality fuels the debate about the ethical implications of DBS.

186 stem has profound theoretical, clinical, and ethical implications.

187 with wide-ranging theoretical, clinical, and ethical implications.

188 etermination of paramount social, legal, and ethical import.

189 olds both, manually validated scientific and ethical information on hPSC lines, and provides access b

190 each other about them across differences of ethical intuition.

191 We outline each ethical issue and discuss how it can be conceptualized a

192 ion with zebrafish constitutes a complicated ethical issue that calls for the exploration of alternat

193 Randomizing patients was also novel, and the ethical issues are discussed.

194 Ethical issues arise when decisions have to be made rega

195 ing human organoids and gastruloids involves ethical issues associated with their derivation as well

196 d donors for chain-initiating kidneys raises ethical issues concerning the consent process for each i

197 Many of the ethical issues encountered during the PsA-TT clinical de

198 perts in community engagement strategies and ethical issues germane to vaccination policies, includin

199 media communities magnify and modify extant ethical issues in deceased and living donation related t

200 linicians must carefully consider these core ethical issues in order to make the most of this excitin

201 This may give rise to significant ethical issues in that the treatment may well directly b

202 Careful consideration of the ethical issues involved is critical to the safe and appr

203 state-of-the art approach to the debates on ethical issues is key in order to gain guidance on resea

204 At the same time, any ethical issues likely to arise in such studies should be

205 c testing carries great promise, but several ethical issues must be considered whenever such testing

206 ew source of therapeutic cells free from the ethical issues or immune barriers of human embryonic ste

207 and South America explored the practical and ethical issues pertaining to pediatric deceased donation

208 this article, we highlight the institutional ethical issues raised by this outbreak, and propose a na

209 on on pregnant women and their fetuses raise ethical issues regarding consent for future data mining

210 Policy, we provide an overview of the major ethical issues related to dialysis provision worldwide,

211 objective of this article is to explore core ethical issues related to physician-assisted suicide and

212 and donor candidates; address the moral and ethical issues surrounding the procedure; outline the te

213 e second concerns the urgent need to address ethical issues when evaluating the state of artificial i

214 domised controlled trials (partly because of ethical issues), few prospective and long-term studies,

215 rspectives of patients with cancer regarding ethical issues.

216 esources, health and safety goals, and other ethical issues.

217 orientated care aspects, and medicolegal and ethical issues.

218 es present several unique methodological and ethical issues.

219 novations may expand KPD, they raise several ethical issues.

220 forms of subjectivity found in all analyses: ethical judgments, made when setting the terms of an ana

221 base that supports its clinical use, (c) an ethical justification, and (d) a transparent public proc

222 Observations: We reviewed the ethical justifications for and against truth-telling, an

223 New curricula in the study of the ethical, legal and social implications of scientific res

224 lic solicitation that is consistent with the Ethical, Legal, and Psychosocial Aspects of Transplantat

225 linical validity and utility, as well as the ethical, legal, and social implications of sequencing vi

226 epresents current opinion by the ASHG on the ethical, legal, and social issues concerning genetic tes

227 hold great promise, they also raise profound ethical, legal, and social questions.

228 oethical Issues (Anticipate and Communicate: Ethical Management of Incidental and Secondary Findings

229 strategies to streamline study conduct in an ethical manner to optimally perform clinical trials in t

230 poor teamwork, deceptive communication, and ethical misconduct.

231 ined with growing economic pressures and the ethical need to minimise the use of laboratory animals,

232 Since the early 1970s, the ethical norm governing counselors involved in testing an

233 approach is needed to fulfill the humane and ethical obligation to make palliative care universally a

234 to support institutional fulfillment of the ethical obligation to protect the health of patients by

235 Nevertheless, this historic change brings ethical opportunities and challenges.

236 ng costs, demand by regulatory agencies, and ethical or moral concerns.

237 hus remains premature to include China as an ethical partner in the international transplant communit

238 ree different institutions, with appropriate ethical permissions.

239 Meta-ethical pluralism gives us additional insight into how m

240 use of sham surgery is controversial from an ethical point of view.

241 s an attractive compromise between competing ethical positions, and thus provides a possible resoluti

242 llenges in children and teenagers, including ethical, practical, and scientific issues.

243 ow the donation physician role might promote ethical practice in deceased donation medicine.

244 d safety while preserving the application of ethical precepts.

245 argue that the choice of discount rate is an ethical primitive: there are many different legitimate o

246 l Practices (GCP) and in accordance with the ethical principles that have their origins in the Declar

247 ances as well as identification of important ethical principles to consider.

248 aviors, such as extreme altruism, the use of ethical principles, and romantic love.

249 atment-resistant depression does not violate ethical principles; however, clinicians and professional

250 animal-based production is, however, a major ethical problem.

251 The ethical problems as well as the technical difficulties a

252 nquiry aimed at mapping out solutions to the ethical problems raised by them.

253 However, this approach poses ethical problems, given that the donor is exposed to sur

254 e difficult to conduct due to logistical and ethical problems.

255 he subject has grown in recent years despite ethical prohibitions.

256 lnerabilities contribute to the barriers and ethical quandaries in living kidney donation in Asia.

257 differing positions on the first three core ethical questions and achieved unanimity on how critical

258 (2) alertness and preparedness for emerging ethical questions during the research and in the context

259 Finally, we consider some of the ethical questions raised regarding the research program

260 ity to combine these with other methods, and ethical questions that are special to brain stimulation.

261 s linked to novel technologies and difficult ethical questions that characterize leading climate miti

262 waste time and resources but also may raise ethical questions, especially in drug development studie

263 Neuroscience advances have brought important ethical questions.

264 iene (WASH) interventions without presenting ethical questions.

265 e between partners to explore and answer all ethical questions; (2) alertness and preparedness for em

266 to protect consumers who, out of medical or ethical reasons, reject specific meat fractions.

267 For ethical reasons, the access to in vivo data obtained on

268 for informed consent as the underpinning of ethical research in humans.

269 Intensive care teams are not meeting their ethical responsibility to recognize impending death and

270 ch data cannot be shared because of legal or ethical restrictions.

271 Informed consent of the patient and ethical review board approval was obtained (Code: 2010/0

272 All examinations were performed with ethical review board approval; written informed consent

273 The Stockholm Regional Ethical Review Board approved the study.

274 Institutional ethical review board approved this retrospective study a

275 approval for the study was obtained from the ethical review board of the Netherlands Association for

276 This retrospective study was approved by the ethical review board, and the need to obtain informed co

277 Approval of the institutional ethical review committee was not required.

278 ms, and potentially reduced standards in the ethical review of research by institutional review board

279 ers from a diverse setting of countries, the ethical review process was complex and required strategi

280 Methods An institutional exemption from full ethical review was granted for the study.

281 efficiency and feasibility while maintaining ethical rigor, patient safety, information value, and sc

282 efficiency and feasibility while maintaining ethical rigor, patient safety, information value, and sc

283 An analysis of past ethical scandals, as well as the bioethics apparatus tha

284 Numerous ethical, scientific, business, and legislative incentive

285 legislation as the basis of their policy on ethical standards in experiments on non-human animals.

286 ere it is due and call attention to evolving ethical standards in science.

287 rmation, hPSCreg stores extensive data about ethical standards regarding cell sourcing and conditions

288 have been undertaken to conform to accepted ethical standards.

289 ed four issues highlighting the key areas of ethical tension central to evaluating physician-assisted

290 is approach; however, it would not have been ethical to enroll a contemporaneous population not provi

291 efforts to historicize but not minimize past ethical transgressions.

292 optimism tempered by evidence to support the ethical translation of gene therapy and other novel biot

293 he result is a collection of expert views on ethical trial design, research during outbreaks, high-bu

294 dies that would support safe, effective, and ethical use of ketamine in depression.

295 ensure the continued availability of and the ethical use of research pathology specimens.

296 ation access and sharing and responsible and ethical use of such collections.

297 ad donor strategy is more acceptable from an ethical viewpoint, but its feasibility is currently unpr

298 Materials and Methods An ethical waiver was obtained for this 23-year retrospecti

299 After an ethical waiver was obtained, 38 patients with an HM were

300 rom noncrisis scenarios is not viable and on ethical ways of determining what happens in the absence