ライフサイエンスコーパス: ethnically

1 dependent sample (n = 199) was distinct both ethnically (87.7% Caucasian) and socioeconomically (less

2 ments interspersed within the chromosomes of ethnically admixed individuals.

3 ffness measure (LSM) needs to be explored in ethnically and anthropometrically diverse healthy subjec

4 The base case was an ethnically and gender-mixed adult population with no pri

5 In this ethnically and geographically diverse group of 5106 stud

6 on (+/-) polymorphism in DNA samples from 16 ethnically and geographically diverse human populations

7 suggest that the classifier is robust across ethnically and geographically diverse populations regard

8 nge of exposure levels, and the inclusion of ethnically and geographically diverse populations.

9 %) in the ARREST SCA cohort compared with an ethnically and geographically matched set of controls (0

10 netics analyses and compared across a set of ethnically and geographically targeted reference collect

11 There were 700 low-income, ethnically and linguistically diverse patients with a me

12 dy identifies predictors of depression in an ethnically and racially diverse population of patients w

13 re unique to middle- to older-aged racially, ethnically, and occupationally diverse adults and were t

14 For each patient, 2 ethnically- and sex-matched controls were obtained, 1 ma

15 ents with RA and a group of 448 racially and ethnically balanced control subjects, for all combinatio

16 These relatively mild changes may reflect an ethnically based resistance to the damaging effects of h

17 " phylogeny, with some branches specific for ethnically defined cohorts.

18 de polymorphisms in SLCO1A2 upon analyses of ethnically defined genomic DNA samples (n = 95 each for

19 to help predict radiation response using 277 ethnically defined human lymphoblastoid cell lines (LCLs

20 sion and IC(50) values for both drugs in 197 ethnically defined Human Variation Panel lymphoblastoid

21 Four clinically and ethnically defined patient groups were analyzed.

22 These markers were genotyped in four ethnically defined populations that contained 48 each of

23 els of allele-frequency differential between ethnically defined samples, and we demonstrate, using lo

24 e compare serum and biliary sterol levels in ethnically different populations of patients with gallst

25 European populations are also observed in an ethnically distinct Costa Rican population, but age and

26 identified mutations of alphaIIb(P145) in 3 ethnically distinct families affected by Glanzmann throm

27 We studied four ethnically distinct families affected with this apparent

28 egate with a similar clinical syndrome in an ethnically distinct family.

29 We conducted a longitudinal study in two ethnically distinct groups of healthy young adults in Ca

30 genome is characterized by the emergence of ethnically distinct lineages or haplogroups.

31 8,595 individuals from 12 populations and 6 ethnically distinct major human evolutionary phylogeneti

32 on match the genetic data within village and ethnically distinct municipalities, but underestimate di

33 e context of a large number of controls from ethnically distinct populations sequenced with orthogona

34 5) is associated with allergic phenotypes in ethnically distinct populations, but the underlying mech

35 roach, combining large-scale genotyping in 2 ethnically distinct populations, cis-eQTL (expression qu

36 could guide planning for the needs of other ethnically distinct populations.

37 ciated with various phenotypes of allergy in ethnically distinct populations.

38 association with T1R in 2 geographically and ethnically distinct populations: a family-based sample f

39 ng free-living persons in geographically and ethnically distinct US cities.

40 We tested a second, ethnically distinct, family for cosegregation of disease

41 SNPs in many SULTs are ethnically distributed, another factor that could influe

42 ompare NMO/NMOSD seroepidemiology across two ethnically divergent populations.

43 morphism chip with 2722 variants in a large, ethnically diverse (144 AA and 551 non-AA) adult kidney

44 Participants (N=210) were ethnically diverse (46% were nonwhite), with a mean base

45 n, Hispanic-Latino and Asian self-designated ethnically diverse (ED) origins with normal karyotype, v

46 nationally representative sample of healthy, ethnically diverse 20- to 59-yr-old adults, moderate CKD

47 Subjects were 1056 ethnically diverse adolescents ascertained from clinical

48 model-validation groups included 321 and 93 ethnically diverse adults, respectively.

49 cognitive performance among young, healthy, ethnically diverse adults.

50 Examining ethnically diverse African genomes, we identify variants

51 oning and modestly lower hospitalizations in ethnically diverse ambulatory care patients who have hea

52 This study evaluated 218 patients in an ethnically diverse ambulatory nephrology practice at the

53 s, asthma diagnosis, and lung function in an ethnically diverse and geographically dispersed populati

54 for major depression is effective for these ethnically diverse and impoverished patients.

55 and demographic risk factors of hip OA in an ethnically diverse and physically active population of U

56 d their potential effect on mental health in ethnically diverse areas.

57 servational study assessed 2292 racially and ethnically diverse boys (1254 [54.7%]) and girls (1038 [

58 workforce to meet the needs of racially and ethnically diverse cancer patients; increase prioritizat

59 COMET enrolled 469 ethnically diverse children (ages, 6-11 years) with myop

60 ants were 186 socioeconomically and racially/ethnically diverse children (mean age, 10.3 years; age r

61 ide cross-sectional data on a large group of ethnically diverse children with myopia.

62 cipants with complete data were 402 racially/ethnically diverse children, with a mean age of 7.7 year

63 This racially and ethnically diverse cohort (38% white, 40% African Americ

64 bsequent analysis of the N190K variant in an ethnically diverse cohort identified this isoform in a s

65 of subclinical atherosclerosis, in a large, ethnically diverse cohort of 14,812 patients for the pre

66 We analyzed DNA from an ethnically diverse cohort of 188 individuals to identify

67 eristics and body composition in an racially-ethnically diverse cohort of antiretroviral-naive patien

68 's Health Initiative Observational Study, an ethnically diverse cohort of postmenopausal women includ

69 N10 gene with diabetes risk in our large and ethnically diverse cohort of postmenopausal women.

70 associated with delayed OL in a racially and ethnically diverse cohort of postpartum women with recen

71 ic Study of Atherosclerosis, a longitudinal, ethnically diverse cohort study of US men and women aged

72 l study includes a large, geographically and ethnically diverse cohort, rich depth of phenotypic info

73 tance of studying genetic associations in an ethnically diverse cohort.

74 ons were applied to 6 prospectively studied, ethnically diverse cohorts (n = 23 424), including white

75 Ethnically diverse cohorts of 6- to 8-year-old girls (n

76 were recruited from four geographically and ethnically diverse communities in the United States.

77 The sample consisted of an ethnically diverse community cohort of 3,302 pre- and ea

78 By use of a racially/ethnically diverse community sample of nearly 3,300 midl

79 d health practices and outcomes; however, no ethnically diverse community-based study has examined di

80 profiles can increase the quality of life of ethnically diverse dementia caregivers.

81 tive 3-year study in community hospital with ethnically diverse elderly population.

82 at end of life was an option selected by an ethnically diverse elderly population.

83 genomic DNA from a panel of 97 racially and ethnically diverse FA patients from the International Fa

84 We have identified five further ethnically diverse families cosegregating CRD and AI.

85 tation (R96L) was recurrently found in three ethnically diverse families with an autosomal dominant m

86 We report 4 cases from 3 ethnically diverse families with MPV17 mutations.

87 We performed one of the most racially/ethnically diverse fine-mapping genetic studies of HDL-C

88 CRIC will include a racially and ethnically diverse group of adults aged 21 to 74 yr with

89 28B genotype, we examined viral levels in an ethnically diverse group of injection drug users (IDUs).

90 certain the frequency of GBA mutations in an ethnically diverse group of patients with Parkinson's di

91 Willebrand factor (VWF) through the study of ethnically diverse healthy controls and, in doing so, ex

92 and left ventricle (LV) structure in a large ethnically diverse Hispanic cohort.

93 rized genetic variation within introns using ethnically diverse human polymorphism data from three pu

94 e variation in the genes MSX1 and PAX9 in an ethnically diverse human population.

95 at these genes and resequenced them in three ethnically diverse human populations.

96 opsin gene (OPN1LW) in 236 individuals from ethnically diverse human populations.

97 We resequenced 80 ethnically diverse individuals across the TH locus.

98 In addition, we analyzed ethnically diverse individuals within the 1000 genomes p

99 A total of 223 ethnically diverse infants born at 30 + 0 to 36 + 6 wk o

100 ABCA3 gene in blood DNA from 21 racially and ethnically diverse infants with severe neonatal surfacta

101 he San Diego Population Study enrolled 2,404 ethnically diverse men and women 29 to 91 years of age w

102 e taken forward to a validation study of 123 ethnically diverse men from Chicago who had previously u

103 ased survey of fragile X (FRAXA) syndrome in ethnically diverse metropolitan Atlanta.

104 Photographs of 12 ethnically diverse models (black, white, and Asian) were

105 ed tomographic imaging (SPECT) imaging in an ethnically diverse multicenter registry.

106 ted decline in cognitive function domains in ethnically diverse older adults, including African Ameri

107 ginally found mutations and from a new, more ethnically diverse panel.

108 stratified random sample of 435 racially and ethnically diverse participants from 15 of 40 WHI clinic

109 scan for genotype-by-sex interactions in the ethnically diverse participants in the EVE Asthma Geneti

110 ing (HEIRS) Study was a multicenter study of ethnically diverse participants that tested for the hemo

111 ent of a therapeutic vaccine for a large and ethnically diverse patient population.

112 the dose requirements in geographically and ethnically diverse patient populations, is needed before

113 AR levels are elevated in geographically and ethnically diverse patients with FSGS and do not reflect

114 phism at NPY1R by systematic resequencing in ethnically diverse people.

115 CRTh2 rs533116 was genotyped in an ethnically diverse population (n = 1282).

116 er whole genome sequence information from an ethnically diverse population and, therefore, is a rich

117 and the risk of breast cancer in a racially/ethnically diverse population comprising mainly women wh

118 An ethnically diverse population of 303 men and women with

119 e Toronto Nutrigenomics and Health Study, an ethnically diverse population of healthy young adults.

120 The same loci were then typed in three ethnically diverse population samples.

121 lent patient and kidney graft survival in an ethnically diverse population with risk factors for poor

122 Examining an ethnically diverse population with uniform health care c

123 ammation and show that these relations in an ethnically diverse population with unique dietary habits

124 ins can be extended to an intermediate-risk, ethnically diverse population without cardiovascular dis

125 events than placebo in an intermediate-risk, ethnically diverse population without cardiovascular dis

126 In our urban, ethnically diverse population, a risk-factor approach is

127 BMI), and mammographic density in a racially/ethnically diverse population-based sample of 522 postme

128 ated with complex diseases in several large, ethnically diverse population-based studies.

129 CR and viral culture in a geographically and ethnically diverse population.

130 ris County, Texas, a county with a large and ethnically diverse population.

131 lung function in a large geographically and ethnically diverse population.

132 unity mental health organizations serving an ethnically diverse population.

133 coding region variants of CNT1 identified in ethnically diverse populations (100 African Americans, 1

134 erize CYP3A5 variation in geographically and ethnically diverse populations from in and around Africa

135 ms to increase participation of racially and ethnically diverse populations in cancer clinical trials

136 r disease (ASCVD) events in contemporary and ethnically diverse populations is not well understood.

137 By fine mapping and genomic re-sequencing in ethnically diverse populations, we fully characterized t

138 tudies are limited and largely have excluded ethnically diverse populations.

139 large sample sizes (>100,000) or studies in ethnically diverse populations.

140 d COL3A1 in 48 individuals from each of four ethnically diverse populations.

141 sociated with allergic phenotypes in several ethnically diverse populations.

142 (96 kb; 57% coding) in 247 DNA samples from ethnically diverse populations.

143 now been described in adRP patients of four ethnically diverse populations.

144 cases, 118,538 controls) of individuals from ethnically diverse populations.

145 ct of large-scale CF carrier screening in an ethnically diverse pregnant population.

146 el imputation of summary statistics from the ethnically diverse Psychiatric Genetic Consortium Schizo

147 bution of such rare alleles by genotyping an ethnically diverse reference sample that is more than si

148 e nucleotide polymorphisms were genotyped in ethnically diverse replication samples from 9 different

149 ased psoriasis had more than 20% racially or ethnically diverse research participants as compared wit

150 y predict dorsal striatal D2R in 117 healthy ethnically diverse residents of the New York metropolita

151 scores with placental mtDNAcn in a racially/ethnically diverse sample (n = 147) from the Programming

152 domized controlled trial was conducted in an ethnically diverse sample of 164 overweight and obese [b

153 gle-nucleotide polymorphism (SNP) loci in an ethnically diverse sample of humans revealed consistentl

154 ctive study of this association involving an ethnically diverse sample of middle-aged men and women.

155 isite, longitudinal, prospective study of an ethnically diverse sample, 215 patients age 14 to 39 yea

156 inct evolutionary patterns for these loci in ethnically diverse samples (26 populations for DQB1 and

157 Approximately 62,000 ethnically diverse samples from eleven Cohorts for Heart

158 We enrolled 548 ethnically diverse schoolchildren (age 11.7 years, SD 0.

159 y medical schools assert that a racially and ethnically diverse student body is an important element

160 ct the gut microbiome in a relatively large, ethnically diverse study population of infants at age 3

161 polymorphisms (SNPs) by resequencing NRF2 in ethnically diverse subjects, and one (-617 C/A) signific

162 In a cohort of 90 ethnically diverse subjects, we resequenced the TLR4 loc

163 gion of OCTN2 in a large sample (n = 276) of ethnically diverse subjects.

164 ing DNA from a large sample (n = 247-276) of ethnically diverse subjects.

165 An ethnically diverse subsample of 2,996 mostly healthy pos

166 harmful, drawing on multilevel data from 56 ethnically diverse Tanzanian villages.

167 The first sample consisted of ethnically diverse third-grade children, and the second

168 n among men and women and was present in the ethnically diverse total cohort as well as in the majori

169 ntigens of large populations of racially and ethnically diverse transplant donors and recipients.

170 ysis of skin cancer morbidity and risk in an ethnically diverse transplant population from which we d

171 t intervals for strategic surveillance in an ethnically diverse transplant population.

172 otal WBC and differential counts in a large, ethnically diverse US population sample of Hispanics/Lat

173 of sudden infant death syndrome (SIDS) in an ethnically diverse US population, the authors conducted

174 Mean age: 78 years, 60% female, ethnically diverse with 46% white, and 54% others.

175 The population of adolescents was ethnically diverse with an average age of 15.4 years.

176 ht and waist circumference in 3,064 racially/ethnically diverse women aged 42-52 years at baseline wh

177 spective of etiology, women were older, more ethnically diverse, and had higher systolic blood pressu

178 The trial was conducted in an ethnically diverse, inner-city neighborhood; thus, resul

179 Data were collected from 4512 ethnically diverse, nonmyopic school-aged children from

180 s between serum HA and radiographic OA in an ethnically diverse, population-based sample.

181 he Multi-Ethnic Study of Atherosclerosis, an ethnically diverse, population-based, US study.

182 patients was 13 years and the population was ethnically diverse.

183 s of optometry in the United States and were ethnically diverse.

184 nce enhances armed-conflict outbreak risk in ethnically fractionalized countries.

185 nature of these events seems to play out in ethnically fractionalized societies in a particularly tr

186 ions and (ii) these same effects can explain ethnically heterogeneous classical allelic associations

187 Previous studies have emphasized ethnically heterogeneous human leukocyte antigen (HLA) c

188 y represent promising vaccine candidates for ethnically heterogeneous populations.

189 question, about 23% of conflict outbreaks in ethnically highly fractionalized countries robustly coin

190 genotyped members of Generation Scotland, an ethnically homogeneous cohort from five sites across Sco

191 erform a genome-wide association study in an ethnically homogeneous cohort of 904 schizophrenia cases

192 s been associated with viral clearance in an ethnically homogeneous cohort.

193 in imaging, small sample sizes, and racially/ethnically homogeneous cohorts with biased selection bas

194 cit assumptions make them applicable only to ethnically homogeneous cohorts.

195 n on millions of variants from 40 additional ethnically homogeneous genomes from the Korean Personal

196 We found that in ethnically homogeneous Latino communities, partners are

197 We randomly assigned participants to ethnically homogeneous or diverse markets.

198 Japan has an ethnically homogeneous population with a low incidence o

199 n rs7566605 and body mass index in two large ethnically homogeneous population-based cohorts.

200 Results evaluating 25(OH)D in ethnically homogeneous populations may not be broadly ge

201 This study confirms in a large and ethnically homogeneous sample that IRS1 G972R polymorphi

202 All individuals were recruited from an ethnically homogeneous white population in Oxfordshire,

203 dentify regions of excess homozygosity in an ethnically homogenous cohort: 904 schizophrenia cases an

204 Since the Czech Republic had an ethnically homogenous population, virtually universal pr

205 pendent of MTHFR genotype within the largest ethnically homogenous subgroup, persons of Northern and/

206 ocular biometric measures in an independent ethnically matched Caucasian cohort.

207 The p.Gly97Arg was absent in 800 ethnically matched chromosomes and 1400 in-house exome d

208 d mutations were absent in two panels of 192 ethnically matched control chromosomes.

209 reaction products, and was excluded from 100 ethnically matched control individuals by restriction en

210 with the disease, and is not detected in 121 ethnically matched control individuals.

211 n 20 years and 147 community age-, sex-, and ethnically matched control participants in the greater N

212 patients with Crohn's disease (CD), and 338 ethnically matched control patients treated at LAC-USC a

213 y of rare TLR4 coding changes to those in an ethnically matched control population.

214 None of these alleles was found in 97 ethnically matched control samples.

215 sis of 42 Mexican-American IDDM families and ethnically matched control subjects by polymerase chain

216 alyzed by comparing diLQTS patients with 515 ethnically matched control subjects from the National He

217 s with AMD with a series of age, gender, and ethnically matched control subjects with no known histor

218 icans with tuberculosis (TB) disease and 187 ethnically matched control subjects.

219 cleotide variants or in 634 chromosomes from ethnically matched control subjects.

220 ies and cone disorders (6/488) compared with ethnically matched controls (35/18 682; P < 0.0001), sug

221 acquired aplastic anemia (AA) but not in 276 ethnically matched controls (Fisher exact test, P < .004

222 149) from the Manitoba IBD Cohort Study and ethnically matched controls (n = 142) were genotyped for

223 nally relevant domains and are absent in 480 ethnically matched controls (p = 0.014, Fisher's exact t

224 01, odds ratio [OR] = 3.7), and with normal, ethnically matched controls (P = 3 x 10(-7), Pcorr = 1 x

225 We screened 36 ATLL patients and 24 ethnically matched controls and found 4 patients with mu

226 talian, Spanish and Swedish origin and 1,354 ethnically matched controls and from 92 CBE case-parent

227 in 410 children with ADHD and 1156 unrelated ethnically matched controls from the 1958 British Birth

228 nformatics tools, and were not identified in ethnically matched controls or within variant databases.

229 within the family and was not identified in ethnically matched controls or within variant databases.

230 lies, and neither mutation was identified in ethnically matched controls or within variant databases.

231 ns, these data show the importance of either ethnically matched controls or within-family-based disea

232 atients with CD, 73 patients with UC, and 60 ethnically matched controls using microsatellite markers

233 88 patients with other forms of CHD and 6760 ethnically matched controls using single nucleotide poly

234 American SLE cohort of 158 patients and 223 ethnically matched controls was determined using fluores

235 non-familial sporadic cases) and 402 healthy ethnically matched controls were employed.

236 deletion mutation (c.99-100delTC)] absent in ethnically matched controls were identified in a screen

237 ed people with PEX syndrome and 225 age- and ethnically matched controls were recruited for genetic a

238 Ethnically matched controls were screened for all mutati

239 ls (cases) from Sweden and Iceland and 1,090 ethnically matched controls, and we performed replicatio

240 , absent in more than 2,500 chromosomes from ethnically matched controls, in the ciliary gene NEK2, e

241 provided by the absence of the variants from ethnically matched controls, phylogenetic conservation,

242 e limited number of biopsy-proven cases with ethnically matched controls, we devised an analytic stra

243 s among people of European descent and 5,140 ethnically matched controls, with replication in an inde

244 10-fold higher than reported frequencies in ethnically matched controls.

245 unrelated Caucasian patients with WG and 421 ethnically matched controls.

246 A497P) and that were absent from at least 80 ethnically matched controls.

247 essive-compulsive disorder (OCD) than in 253 ethnically matched controls.

248 a large group of SSc and PM/DM patients and ethnically matched controls.

249 re 136 patients with GCA and/or PMR with 147 ethnically matched controls.

250 ed with early-onset breast cancer and in 215 ethnically matched controls.

251 ts: 571 white schizophrenic patients and 639 ethnically matched controls.

252 ent in available databases or in 150 healthy ethnically matched controls.

253 ease (SCD) receiving blood transfusions from ethnically matched donors.

254 the IPT cohort were similar to those in the ethnically matched general population.

255 derived cohort and a Hispanic cohort) and in ethnically matched healthy controls.

256 n patients with JIA living in the UK and 728 ethnically matched healthy controls.

257 typing in 826 UK Caucasian JIA cases and 617 ethnically matched healthy controls.

258 radic chondrocalcinosis or pseudogout and in ethnically matched healthy controls.

259 A-4 in 117 American patients with WG and 123 ethnically matched healthy controls.

260 colitis, 42 Crohn's disease patients, and 93 ethnically matched healthy controls.

261 ced in DNA from 39 Saudi VKH patients and 50 ethnically matched healthy individuals.

262 ashion and was not detected in 275 unrelated ethnically matched healthy subjects.

263 the results were compared with those in 203 ethnically matched healthy volunteers.

264 pus erythematosus patients compared with 150 ethnically matched normal controls (p = 0.024).

265 both anti-beta2GPI-negative SLE patients and ethnically matched normal controls, especially in Mexica

266 e low/null NQO1 activity than expected in an ethnically matched population of disease-free subjects (

267 of the expected genotype distribution in an ethnically matched population of disease-free subjects s

268 and UK psoriasis cohorts (combined n=691) to ethnically matched populations (combined n=2117).

269 conserved residues and were absent in >1000 ethnically matched reference alleles.

270 patients were compared with frequencies from ethnically matched UK (n = 386) and Czech (n = 179) cont

271 ian patients with systemic-onset JIA and 384 ethnically matched unrelated control subjects.

272 We typed 680 patients with JRA and 254 ethnically matched unrelated controls for HLA class I an

273 d 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls.

274 northern European Caucasoid patients and 102 ethnically-matched control subjects were tested by polym

275 ercise test argue for the use of appropriate ethnically-matched controls.

276 erage of >8 of 10 held-out individuals in an ethnically mixed cohort and an average of 5 of either 10

277 otope dilution) methods (ECW(TBK-TBW)) in an ethnically mixed group of children and adults.

278 oid dependent affected sibling pairs from an ethnically mixed population of methadone maintained subj

279 d periodontopathogenic bacteria in a larger, ethnically mixed population of subjects with periodontit

280 common ancestry, as well as those that exert ethnically more restricted effects.

281 nt differences were found between parents of ethnically/racially diverse children and parents of non-

282 A total of 207 eyes from an ethnically/racially diverse group of 207 patients (mean

283 nts showed highly variable frequencies among ethnically related cohorts.

284 We find that the ethnically relevant consensus reference can be beneficia

285 ch may be detected more efficiently using an ethnically relevant or personal reference.

286 acilitate establishing a more culturally and ethnically sensitive health care environment for patient

287 Ethnically sensitive methods were used to evaluate the c

288 o-N-neotetrose and DSLNT] were shown between ethnically similar (and likely genetically similar) popu

289 NPs available to categorize individuals into ethnically similar clusters and it does not require assu

290 vailable exomes and absent in more than 1000 ethnically similar control patients, were discovered in

291 Three hundred twenty-one AMD patients, 192 ethnically similar control subjects, 39 unrelated proban

292 DNA samples from 155 patients and 102 ethnically similar normal individuals were assessed by p

293 in at least 300 control chromosomes from an ethnically similar population.

294 ase-control design was used in a purposively ethnically stratified multisite sample of 1,004 women in

295 topes, should be useful for the design of an ethnically unbiased, therapeutic CTL vaccine for the tre

296 CTL epitope will be useful for the design of ethnically unbiased, widely applicable immunotherapies f

297 o identify other class II associations in an ethnically varied cohort, molecular class II HLA typing