ライフサイエンスコーパス: ethyl pyruvate

1 e hydrogenation of alpha-keto esters such as ethyl pyruvate.

2 When mice were treated with ethyl pyruvate (40 mg/kg intraperitoneally every 6 hrs f

3 ts to possible adsorption changes induced by ethyl pyruvate, a common reactant in chiral hydrogenatio

4 te pancreatitis, the same dosing regimen for ethyl pyruvate also ameliorated bacterial translocation

5 Treatment with ethyl pyruvate ameliorated the local inflammatory respon

6 r outcomes were obtained with the functional ethyl pyruvate analogue 2-acetamidoacrylate.

7 Lipid A analog, phospholipid emulsion, and ethyl pyruvate are currently being evaluated for potenti

8 y providing a compelling basis to reposition ethyl pyruvate as a low-cost immunochemotherapy for clin

9 potential were hepatocyte growth factor and ethyl pyruvate, because they seem to protect against or

10 bility to interfere with NF-kappaB function, ethyl pyruvate blocks IDO induction both in vitro and in

11 Treatment with ethyl pyruvate decreased pancreatic expression of tumor

12 e that the low-cost, anti-inflammatory agent ethyl pyruvate elicits a potent immune-based antitumor r

13 Recent studies indicate that ethyl pyruvate (EP) exerts anti-inflammatory properties;

14 Ethyl pyruvate (EP) has pharmacologic effects that remed

15 to evaluate the anti-inflammatory effect of ethyl pyruvate (EP) in a mouse model of lipopolysacchari

16 Our previous studies indicate that ethyl pyruvate (EP) inhibits tumor necrosis factor (TNF)

17 Ethyl pyruvate (EP) recently was identified as an experi

18 Ethyl pyruvate (EP) treatment inhibits nuclear factor (N

19 f this study was to test the hypothesis that ethyl pyruvate (EP), a soluble pyruvate derivative, is e

20 Ethyl pyruvate (EP), an off-the-shelf agent, appears to

21 t for the substitution of either pyruvate or ethyl pyruvate for lactate, respectively.

22 oxidative and ageing aroma compounds such as ethyl pyruvate, furfural or dioxanes in higher concentra

23 so been promising research results involving ethyl pyruvate, glycogen synthase kinase-3 inhibitors an

24 Ethyl pyruvate has been shown to be an effective anti-in

25 Ethyl pyruvate has been shown to improve cardiac functio

26 Treatment with ethyl pyruvate has been shown to improve survival and am

27 Ethyl pyruvate has been tested in human volunteers and s

28 Although ethyl pyruvate has undergone early-phase clinical testin

29 rent that certain pyruvate esters, including ethyl pyruvate, have pharmacological effects, such as su

30 ory formulated a derivative of pyruvic acid, ethyl pyruvate, in a calcium- and potassium-containing b

31 Ethyl pyruvate is a simple derivative of the endogenous

32 Ethyl pyruvate is a simple molecule that has been shown

33 en mice were treated with a 40 mg/kg dose of ethyl pyruvate just before the first dose of cerulein an

34 cytoplasmic translocation by agents such as ethyl pyruvate limits starvation-induced autophagy.

35 r volumes of either pyruvate (n = 6 each) or ethyl pyruvate (n = 9) solution made up exactly like lac

36 ansfection or inhibition of HMGB1 release by ethyl pyruvate or other small molecules led predominantl

37 1,2-addition of an alphaC-lithiated O-silyl ethyl pyruvate oxime to benzoquinone, which is followed

38 n mice with a noncytotoxic dosing regimen of ethyl pyruvate shown previously to protect against letha

39 Treatment with ethyl pyruvate solution also significantly decreased the

40 Treatment with Ringer's ethyl pyruvate solution ameliorated structural and funct

41 quent studies, we showed that treatment with ethyl pyruvate solution could improve survival in rodent

42 ent with either Ringer's lactate solution or ethyl pyruvate solution on several physiologic and bioch

43 ent of rats with either pyruvate solution or ethyl pyruvate solution significantly ameliorated the de

44 Ethyl pyruvate solution warrants further evaluation as a

45 ell-dependent immunity and IDO targeting for ethyl pyruvate to achieve antitumor efficacy.

46 findings that IDO is effectively blocked by ethyl pyruvate treatment deepen emerging links between I

47 Recently, ethyl pyruvate was also shown to improve survival in mur

48 Ethyl pyruvate was ineffective at suppressing tumor outg

49 Ethyl pyruvate was shown to ameliorate some of the struc

50 ht to determine whether a simple derivative, ethyl pyruvate, would be protective in an animal model o