ライフサイエンスコーパス: ethylmaleimide

1 teines by oxidation and reaction with NEM (N-ethylmaleimide).

2 blocking the S-nitrosylation reaction with N-ethylmaleimide.

3 to be predominantly modified by thiols or N-ethylmaleimide.

4 e-sensitive factor attachment protein, and N-ethylmaleimide.

5 -nitrosoglutathione, hydrogen peroxide, or N-ethylmaleimide.

6 atment of cells with low concentrations of N-ethylmaleimide (10 microM), suggesting that enrichment w

7 nt, radioactive thiol reagent N-[ethyl-1-14C]ethylmaleimide ([14C]NEM) is used to detect site-directe

8 N-Ethylmaleimide, (2-aminoethyl)-methane thiosulfonate, 2-

9 e the newly formed intermediate selenol by N-ethylmaleimide; (3) deproteinization.

10 Pretreatment with N-ethylmaleimide, a small, membrane-permeating compound th

11 ctivity, and the activity was sensitive to N-ethylmaleimide, a sulfhydryl-modifying reagent.

12 ys in the D'D3 monomer were alkylated with N-ethylmaleimide and analyzed by mass spectrometry.

13 sol-dependent fashion that is sensitive to N-ethylmaleimide and dependent on Sar1 and sec22B.

14 10-kDa molecular mass that is resistant to N-ethylmaleimide and heat inactivation.

15 s prevented by the SNARE protein inhibitor N-ethylmaleimide and the calcium chelator BAPTA.

16 residues to the membrane-permeant reagent N-ethylmaleimide and the membrane-impermeant reagent polye

17 N-Ethylmaleimide and thimerosal were able to simulate the

18 bited by sodium vanadate, sodium fluoride, N-ethylmaleimide, and phenylglyoxal but was not significan

19 species are trapped by cycloaddition with N-ethylmaleimide, and the reactions are traced by high res

20 ve been shown to be covalently modified by N-ethylmaleimide, and this treatment was found to block th

21 ns for activity, was potently inhibited by N-ethylmaleimide, and was labile at temperatures above 40

22 f UL16 would be expected to be modified by N-ethylmaleimide, and, consistent with this, the amount of

23 Furthermore, both N-ethylmaleimide- and H(2)O(2)-induced TRPC6 activations w

24 calcium-dependent Syt1 binding to soluble N-ethylmaleimide attachment protein receptor (SNARE) and v

25 on of Gbetagamma subunits with the soluble N-ethylmaleimide attachment protein receptor (SNARE) compl

26 Although FAK inhibition decreased soluble N-ethylmaleimide attachment protein receptor (SNARE)-media

27 a Golgi-localized target membrane-soluble N-ethylmaleimide attachment protein receptor (t-SNARE) pro

28 ylation were specifically derivatized with N-ethylmaleimide-biotin.

29 nt modification of its free cysteines with N-ethylmaleimide blocked binding to UL11 but not UL21.

30 the membrane-permeable sulfhydryl blocker, N-ethylmaleimide, by the RGD peptide, and by anti-alphaIIb

31 Preventing RyR cross-linking with N-ethylmaleimide decreased the propensity of Ca(2+) waves

32 odification of free cysteines in UL16 with N-ethylmaleimide does in fact prevent binding.

33 ed the role of a vesicle-residing, soluble N-ethylmaleimide factor attachment protein receptor (v-SNA

34 ficking proteins including SNAREs (soluble N-ethylmaleimide factor attachment protein receptors) and

35 semolina protein (g protein) or 13.8 mumol N-ethylmaleimide/g protein reduces gliadin-glutenin cross-

36 trometry after derivatization to yield GSH-N-ethylmaleimide (GSNEM).

37 n all cases, pretreatment with vanadate or N-ethylmaleimide inhibited the conversion of echinocytes t

38 f the completely conserved Cys353) through N-ethylmaleimide modification or mutagenesis to alanine ab

39 o (2-aminoethyl)-methane thiosulfonate and N-ethylmaleimide modification.

40 e redox states of both the as purified and N-ethylmaleimide-modified forms, using the combination of

41 ent of muscle cells with the NSF inhibitor N-ethylmaleimide, mutation of NSF, or suppression of NSF e

42 Sensitivity to N-ethylmaleimide (NEM) and methanethiosulfonate reagents w

43 at was inhibited by the vesicle inhibitors N-ethylmaleimide (NEM) and monensin.

44 Chemical labeling with N-ethylmaleimide (NEM) and tandem mass spectrometry experi

45 ification by the membrane permeant reagent N-ethylmaleimide (NEM) and the membrane impermeant reagent

46 e have investigated the mechanism by which N-ethylmaleimide (NEM) enhances transporter activity using

47 erythrocytes, the cysteine-modifying agent N-ethylmaleimide (NEM) has been shown to inhibit system y(

48 of the protein thiol groups on the MPI by N-ethylmaleimide (NEM) markedly reduced this rate constant

49 ns isolated in the presence and absence of N-ethylmaleimide (NEM), a chemical that reacts irreversibl

50 rate and effect of Cys-159 modification by N-ethylmaleimide (NEM), a cysteine-selective alkylating ag

51 ridine, a known Isomerase I inhibitor, and N-ethylmaleimide (NEM), a known LRAT inhibitor, significan

52 N-ethylmaleimide (NEM), and to a lesser extent, dithio(bis

53 lytes ((310)GSH and (616)GSSG), along with N-ethylmaleimide (NEM), and treated with acetonitrile to s

54 s cGMP independent but could be blocked by N-ethylmaleimide (NEM), indicating that NO acted via an S-

55 Pretreatment with N-ethylmaleimide (NEM), which occludes S-nitrosylation, or

56 e unmodified free thiols are blocked using N-ethylmaleimide (NEM).

57 ation by treatment with the thiol reagent, N-ethylmaleimide (NEM).

58 re more modest with a slight inhibition in N-ethylmaleimide (NEM, 1 mm)-treated RBCs and stimulation

59 y (2-aminoethyl)-methane thiosulfonate and N-ethylmaleimide of cysteine mutant proteins were measured

60 alent thiol modification of reduced PDI by N-ethylmaleimide or methyl-methanethiosulfonate, which abo

61 hemical labeling by isotope-coded forms of N-ethylmaleimide or succinic anhydride to site-specificall

62 es (c = 8 mmol L(-1)), photoligations with N-ethylmaleimide (possible for lambda </= 390 nm) are idea

63 bove their optimums and by Ca(2+), Zn(2+), N-ethylmaleimide, propranolol, and the sphingoid bases sph

64 ganine) lipids, nucleotides (ATP and CTP), N-ethylmaleimide, propranolol, phenylglyoxal, and divalent

65 f reactive electrophiles: glyoxalase I and N-ethylmaleimide reductase.

66 aturating concentrations of the activator, N-ethylmaleimide-S1.

67 -type at near-saturating concentrations of N-ethylmaleimide-S1.

68 release machinery, this assay incorporates N-ethylmaleimide sensitive factor (NSF) and alpha-SNAP, wh

69 ecule binds our two model His(6) proteins, N-ethylmaleimide sensitive factor (NSF) and O(6)-alklyguan

70 reover, we provided evidence for a role of N-ethylmaleimide sensitive factor (NSF) in regulating MuSK

71 related to the single N domains in p97 and N-ethylmaleimide sensitive factor (NSF); N1 of Pex1 is mob

72 We find that lotus encodes N-ethylmaleimide sensitive factor 2 (NSF2), whereas wheezy

73 ion, enabling cooperation with the soluble N-ethylmaleimide sensitive factor adaptor protein receptor

74 significantly reduced formation of soluble n-ethylmaleimide sensitive factor adaptor protein receptor

75 Phosphorylation of this t-soluble N-ethylmaleimide sensitive factor attachment protein recep

76 nct combinations of Munc18 and the soluble N-ethylmaleimide sensitive factor attachment protein recep

77 in, complexin, and neuronal SNARE (soluble N-ethylmaleimide sensitive factor attachment protein recep

78 Sec1/Munc18 (SM) proteins and soluble N-ethylmaleimide sensitive factor attachment protein recep

79 Soluble N-ethylmaleimide sensitive factor attachment protein recep

80 a role for tethering complexes in soluble N-ethylmaleimide sensitive factor attachment protein recep

81 main, which likely participates in soluble N-ethylmaleimide sensitive factor attachment protein recep

82 Evolutionarily conserved SNARE (soluble N-ethylmaleimide sensitive factor attachment protein recep

83 ining lipid bilayers as well as to soluble N-ethylmaleimide sensitive factor receptors (SNAREs) and p

84 N-Ethylmaleimide sensitive factor recycles SNAREs after fu

85 The ATPase NSF (N-ethylmaleimide sensitive factor), together with SNAPs (s

86 The exocytic vesicular soluble N-ethylmaleimide sensitive fusion protein attachment prote

87 the packaging of a SNARE protein (soluble N-ethylmaleimide-sensitive attachment protein receptor) oc

88 ty to tomosyn that are outside the soluble N-ethylmaleimide-sensitive attachment receptor motif.

89 on secretion without altering its soluble N-ethylmaleimide-sensitive attachment receptor pairing wit

90 -1 (stabilizes assembled SNARE complexes), N-ethylmaleimide-sensitive factor (NSF) (disassembles SNAR

91 The time at which the N-ethylmaleimide-sensitive factor (NSF) acts during synapt

92 A soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

93 AAA domain-containing protein 1), soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

94 Soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

95 Soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

96 is directly involved in regulating soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

97 main and modulate the affinity for soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

98 oforms to directly regulate SNARE (soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

99 In eukaryotic cells, the soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

100 Sec17 [soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein

101 N-Ethylmaleimide-sensitive factor (NSF) is a homo-hexameri

102 ptor molecule for the SNARE-priming enzyme N-ethylmaleimide-sensitive factor (NSF) is known to be cru

103 ovel synaptic interaction between Arr1 and N-ethylmaleimide-sensitive factor (NSF) that is enhanced i

104 TPase activity and disassembly activity of N-ethylmaleimide-sensitive factor (NSF), a critical compon

105 nhibits exocytosis by chemically modifying N-ethylmaleimide-sensitive factor (NSF), a key component o

106 kinase Cepsilon (PKCepsilon) regulates the N-ethylmaleimide-sensitive factor (NSF), an ATPase critica

107 he human beta2AR carboxyl end binds to the N-ethylmaleimide-sensitive factor (NSF), an ATPase integra

108 hepatic secretion of VLDL-TAG by targeting N-ethylmaleimide-sensitive factor (NSF), both in vivo and

109 N-ethylmaleimide-sensitive factor (NSF), first discovered

110 te a core complex of proteins comprised of N-ethylmaleimide-sensitive factor (NSF), soluble NSF attac

111 x is disassembled by an AAA+ ATPase called N-ethylmaleimide-sensitive factor (NSF).

112 iPSC-derived human neurons, among them the N-ethylmaleimide-sensitive factor (NSF).

113 zeta maintains late-LTP through persistent N-ethylmaleimide-sensitive factor (NSF)/glutamate receptor

114 ts, whereas further incubation with p97 or N-ethylmaleimide-sensitive factor (two AAA ATPases involve

115 presence of LPC as opposed to cholesterol, N-ethylmaleimide-sensitive factor + adenosine triphosphate

116 vely to the predicted syntaxin and soluble N-ethylmaleimide-sensitive factor accessory protein recept

117 Soluble N-ethylmaleimide-sensitive factor activating protein recep

118 r C-terminus domain and the SNARE (soluble N-ethylmaleimide-sensitive factor activating protein recep

119 r to prevent the completion of the soluble N-ethylmaleimide-sensitive factor activating protein recep

120 of the Rab GTPase Sec4 to promote soluble N-ethylmaleimide-sensitive factor adaptor protein receptor

121 of the Sec4 Rab GTPase to promote soluble N-ethylmaleimide-sensitive factor adaptor protein receptor

122 ined whether genetic disruption of soluble N-ethylmaleimide-sensitive factor attached protein (SNARE)

123 The assembly of the three neuronal soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP

124 Trans-soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP

125 c18-like) protein Munc18-1 and the soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP

126 ARE) complexes in conjunction with soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP

127 (SNAP-25) is a key molecule in the soluble N-ethylmaleimide-sensitive factor attachment protein (SNAR

128 gnate acceptor compartments before soluble N-ethylmaleimide-sensitive factor attachment protein (SNAR

129 which harbors a mutation in Napa [encoding N-ethylmaleimide-sensitive factor attachment protein alpha

130 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

131 inds to and cleaves syntaxin 17, a soluble N-ethylmaleimide-sensitive factor attachment protein recep

132 The soluble N-ethylmaleimide-sensitive factor attachment protein recep

133 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

134 ved increase in K(+) currents is a soluble N-ethylmaleimide-sensitive factor attachment protein recep

135 We identified a member of the soluble N-ethylmaleimide-sensitive factor attachment protein recep

136 ther at the plasma membrane before soluble N-ethylmaleimide-sensitive factor attachment protein recep

137 tic vesicles, including the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

138 tate the formation of trans-SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

139 ric levels with its cognate target-soluble N-ethylmaleimide-sensitive factor attachment protein recep

140 in membrane fusion events are the soluble N-ethylmaleimide-sensitive factor attachment protein recep

141 Membrane fusion is mediated by soluble N-ethylmaleimide-sensitive factor attachment protein recep

142 depends on the disassembly of cis-soluble N-ethylmaleimide-sensitive factor attachment protein recep

143 r release and vesicle recycling in soluble N-ethylmaleimide-sensitive factor attachment protein recep

144 4 vesicle fusion reaction requires soluble N-ethylmaleimide-sensitive factor attachment protein recep

145 ganelles involves the formation of soluble N-ethylmaleimide-sensitive factor attachment protein recep

146 ctural relationships among SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein recep

147 Munc18c binds to the trans-SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

148 fusogens from vesicle trafficking (soluble N-ethylmaleimide-sensitive factor attachment protein recep

149 s requires the concerted action of soluble N-ethylmaleimide-sensitive factor attachment protein recep

150 istence of the unproductive target soluble N-ethylmaleimide-sensitive factor attachment protein recep

151 oteins are important components of soluble N-ethylmaleimide-sensitive factor attachment protein recep

152 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

153 nsulin granules, is carried out by soluble N-ethylmaleimide-sensitive factor attachment protein recep

154 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

155 SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

156 Platelet exocytosis is mediated by soluble N-ethylmaleimide-sensitive factor attachment protein recep

157 the fusion pore induced by SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

158 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

159 e is comparable fusion of 4-SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

160 general membrane fusion machinery-soluble N-ethylmaleimide-sensitive factor attachment protein recep

161 exocytosis by interacting with the soluble N-ethylmaleimide-sensitive factor attachment protein recep

162 synaptic proteins from the soluble SNARE (N-ethylmaleimide-sensitive factor attachment protein recep

163 .1 is postulated to be involved in soluble N-ethylmaleimide-sensitive factor attachment protein recep

164 le marker proteins, glutamate, the soluble N-ethylmaleimide-sensitive factor attachment protein recep

165 abeled vesicle-associated v-SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

166 The soluble N-ethylmaleimide-sensitive factor attachment protein recep

167 and activation of (phago)lysosomal soluble N-ethylmaleimide-sensitive factor attachment protein recep

168 that syt1 might facilitate SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

169 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

170 ediated by the formation of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

171 c syntaxin 1A, and it can activate soluble N-ethylmaleimide-sensitive factor attachment protein recep

172 Arabidopsis (Arabidopsis thaliana) soluble N-ethylmaleimide-sensitive factor attachment protein recep

173 epeated release requires cycles of soluble N-ethylmaleimide-sensitive factor attachment protein recep

174 verexpression of ER/Golgi arginine soluble N-ethylmaleimide-sensitive factor attachment protein recep

175 components: vacuolar lipids, four soluble N-ethylmaleimide-sensitive factor attachment protein recep

176 specific fusion proteins [such as soluble N-ethylmaleimide-sensitive factor attachment protein recep

177 Whereas SNARE (soluble N -ethylmaleimide-sensitive factor attachment protein recep

178 ies of membrane fusion mediated by soluble N-ethylmaleimide-sensitive factor attachment protein recep

179 C2 domains, and the neuronal core soluble N-ethylmaleimide-sensitive factor attachment protein recep

180 eins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein recep

181 ion is mediated by the concerted action of N-ethylmaleimide-sensitive factor attachment protein recep

182 ctivity on one of the three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

183 s derived from target- and vesicle-soluble N-ethylmaleimide-sensitive factor attachment protein recep

184 ularly involving small G proteins, soluble N-ethylmaleimide-sensitive factor attachment protein recep

185 a Gbetagamma interaction with the soluble N-ethylmaleimide-sensitive factor attachment protein recep

186 /Munc18 (SM) proteins bind cognate soluble N-ethylmaleimide-sensitive factor attachment protein recep

187 d botulinum neurotoxin C to cleave soluble N-ethylmaleimide-sensitive factor attachment protein recep

188 th purified yeast vacuolar SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein recep

189 Yeast vacuole fusion requires soluble N-ethylmaleimide-sensitive factor attachment protein recep

190 tter release requires three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

191 ich, in turn, interacts with the lysosomal N-ethylmaleimide-sensitive factor attachment protein recep

192 e transport of the plasma membrane soluble N-ethylmaleimide-sensitive factor attachment protein recep

193 ulinum neurotoxins cleave specific soluble N-ethylmaleimide-sensitive factor attachment protein recep

194 do not contain the t-SNARE (target-soluble N-ethylmaleimide-sensitive factor attachment protein recep

195 and vacuole protein sorting), and soluble N-ethylmaleimide-sensitive factor attachment protein recep

196 The soluble N-ethylmaleimide-sensitive factor attachment protein recep

197 ediated selective concentration of soluble N-ethylmaleimide-sensitive factor attachment protein recep

198 elta) for the Tlg2 target membrane-soluble N-ethylmaleimide-sensitive factor attachment protein recep

199 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

200 ediated by syntaxin 4-based SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

201 Although concentrated soluble N-ethylmaleimide-sensitive factor attachment protein recep

202 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

203 g., microtubules, the exocyst, and soluble N-ethylmaleimide-sensitive factor attachment protein recep

204 interaction of Gbetagamma with the soluble N-ethylmaleimide-sensitive factor attachment protein recep

205 t the regulatory roles of specific soluble N-ethylmaleimide-sensitive factor attachment protein recep

206 vitro and to separate the roles of soluble N-ethylmaleimide-sensitive factor attachment protein recep

207 Synaptic soluble N-ethylmaleimide-sensitive factor attachment protein recep

208 l by cooperating with the neuronal soluble N-ethylmaleimide-sensitive factor attachment protein recep

209 release requires the formation of soluble N-ethylmaleimide-sensitive factor attachment protein recep

210 interact with the vacuolar SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

211 NSF disassembles soluble N-ethylmaleimide-sensitive factor attachment protein recep

212 er with syntaxin-3 and syntaxin-1A soluble N-ethylmaleimide-sensitive factor attachment protein recep

213 component of the synaptic vesicle soluble N-ethylmaleimide-sensitive factor attachment protein recep

214 SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

215 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

216 ituted with the target (t)-SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein recep

217 it a polarized distribution of the soluble N-ethylmaleimide-sensitive factor attachment protein recep

218 e Dawley rats, 4 dominant-negative soluble N-ethylmaleimide-sensitive factor attachment protein recep

219 ted by the formation of functional soluble N-ethylmaleimide-sensitive factor attachment protein recep

220 the Rab GTPase Ypt7p, four SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein recep

221 llular transport vesicles requires soluble N-ethylmaleimide-sensitive factor attachment protein recep

222 abnormal expression or function of soluble N-ethylmaleimide-sensitive factor attachment protein recep

223 Although epsinR is known to be an N-ethylmaleimide-sensitive factor attachment protein recep

224 tro by arresting the late steps of soluble N-ethylmaleimide-sensitive factor attachment protein recep

225 an open conformation to accelerate soluble N-ethylmaleimide-sensitive factor attachment protein recep

226 ansmitters and hormones depends on soluble N-ethylmaleimide-sensitive factor attachment protein recep

227 ice expressing a dominant-negative soluble N-ethylmaleimide-sensitive factor attachment protein recep

228 Neuronal exocytosis is mediated by soluble N-ethylmaleimide-sensitive factor attachment protein recep

229 SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

230 Soluble N-ethylmaleimide-sensitive factor attachment protein recep

231 c13-4 is a Ca(2+)-dependent SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein recep

232 The soluble N-ethylmaleimide-sensitive factor attachment protein recep

233 t work suggested that ER-localized soluble N-ethylmaleimide-sensitive factor attachment protein recep

234 depends on efficient formation of soluble N-ethylmaleimide-sensitive factor attachment protein recep

235 Mast cell degranulation requires N-ethylmaleimide-sensitive factor attachment protein recep

236 anosine 5'-3-O-(thio)triphosphate, soluble N-ethylmaleimide-sensitive factor attachment protein, and

237 protein receptor (SNARE) proteins soluble N-ethylmaleimide-sensitive factor attachment protein-25 (S

238 590 (a predicted alpha-SNAP [alpha-soluble N-ethylmaleimide-sensitive factor attachment protein]).

239 le of the fusion proteins, SNAREs (soluble N-ethylmaleimide-sensitive factor attachment proteins), in

240 ine triphosphate-binding proteins, soluble N-ethylmaleimide-sensitive factor attachment proteins, and

241 ytosis relies on assembly of three soluble N-ethylmaleimide-sensitive factor attachment receptor (SNA

242 In neurons, soluble N-ethylmaleimide-sensitive factor attachment receptor (SNA

243 Syntaxin 1a is a plasma membrane soluble N-ethylmaleimide-sensitive factor attachment receptor prot

244 ns homologous to eukaryotic SNARE (soluble N-ethylmaleimide-sensitive factor attachment receptor) dom

245 yt 1 using a reconstituted, SNARE (soluble N-ethylmaleimide-sensitive factor attachment receptor)-med

246 tail-anchored proteins, including soluble N-ethylmaleimide-sensitive factor attachment receptors (SN

247 ence in the NSF gene, encoding the protein N-Ethylmaleimide-Sensitive Factor essential for synaptic v

248 biting the binding of SNAREs to Sec18p, an N-ethylmaleimide-sensitive factor homologue responsible fo

249 ing the trimerized alphaSNAP, we find that N-ethylmaleimide-sensitive factor hydrolyzes 10 ATP molecu

250 712) or by inhibiting exocytosis (TAT-NSF, N-ethylmaleimide-sensitive factor inhibitor).

251 ;5 are regulated by the SNARE (for soluble N-ethylmaleimide-sensitive factor protein attachment prote

252 SNARE (soluble N-ethylmaleimide-sensitive factor protein attachment prote

253 complex is disassembled by the AAA-ATPase N-ethylmaleimide-sensitive factor that requires the cofact

254 The ATPase NSF (N-ethylmaleimide-sensitive factor) and the adaptor protein

255 an essential component of the soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein rece

256 of proteins known as SNAREs [soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein rece

257 alpha-SNAP [soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein] and

258 attachment protein, and NSF is defined as N-ethylmaleimide-sensitive factor) complexes catalyze syna

259 otypic vesicle fusion by dephosphorylating N-ethylmaleimide-sensitive factor, a key regulator of vesi

260 ent kinase II and the trafficking proteins N-ethylmaleimide-sensitive factor, GABA receptor-associate

261 SNX27-independent recycling may involve N-ethylmaleimide-sensitive factor, which binds both PDZ in

262 al membrane transporters, ATPases, soluble N-ethylmaleimide-sensitive factor-activating protein recep

263 tructures, and here we examine the role of N-ethylmaleimide-sensitive factor-activating protein recep

264 The soluble N-ethylmaleimide-sensitive factor-attachment protein recep

265 uring synaptic vesicle fusion, the soluble N-ethylmaleimide-sensitive factor-attachment protein recep

266 enetic approach to identify target soluble N-ethylmaleimide-sensitive factor-attachment protein recep

267 nd retromer and another possibly involving N-ethylmaleimide-sensitive factor.

268 E hybrid complex cannot be disassembled by N-ethylmaleimide-sensitive factor.

269 cular synapses through cleavage of soluble N-ethylmaleimide-sensitive fusion (NSF) attachment protein

270 ment of Ca(2+) for the assembly of soluble N-ethylmaleimide-sensitive fusion attachment protein recep

271 sicle (DCV) exocytosis is a SNARE (soluble N-ethylmaleimide-sensitive fusion attachment protein recep

272 lates SNAP-23, the target membrane soluble N-ethylmaleimide-sensitive fusion factor attachment protei

273 In addition, mutation of the N-ethylmaleimide-sensitive fusion protein (NSF) binding si

274 We identified a direct interaction between N-ethylmaleimide-sensitive fusion protein (NSF), an ATPase

275 Here we identified Drosophila N-ethylmaleimide-sensitive fusion protein 2 (dNSF2) and so

276 Soluble N-ethylmaleimide-sensitive fusion protein attachment prote

277 integral membrane proteins called soluble N-ethylmaleimide-sensitive fusion protein attachment prote

278 The current model requires soluble N-ethylmaleimide-sensitive fusion protein attachment prote

279 mbrane associated proteins SNAREs (soluble N-ethylmaleimide-sensitive fusion protein attachment prote

280 The soluble N-ethylmaleimide-sensitive fusion protein attachment prote

281 led to assignments of both vesicle-soluble N-ethylmaleimide-sensitive fusion protein attachment prote

282 Soluble N-ethylmaleimide-sensitive fusion protein attachment prote

283 s between synaptotagmin and SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment recep

284 dependent on GluA2 not GluA1, sensitive to N-ethylmaleimide-sensitive fusion protein interaction, and

285 ion requires two AAA ATPases, p97 and NSF (N-ethylmaleimide-sensitive fusion protein), each of which

286 and specific cleavage of neuronal soluble N-ethylmaleimide-sensitive fusion protein-attachment prote

287 sicles in the brain harbor several soluble N-ethylmaleimide-sensitive-factor attachment protein recep

288 ery ECs, depletion of Galpha12 and soluble N-ethylmaleimide-sensitive-fusion factor attachment protei

289 Similarly, l-cysteine and N-ethylmaleimide significantly attenuated the inhibition c

290 , glutathione was derivatized in-situ with N-ethylmaleimide to block the cysteine residue and to enha

291 n when HMM was mixed with ATP-insensitive, N-ethylmaleimide-treated HMM (NEM-HMM; 25-30%).

292 The binding of N-ethylmaleimide-treated myosin subfragment 1 (NEM-S1) to

293 either functionally impaired by trypsin or N-ethylmaleimide treatments or with protein-free liposomes

294 e nonspecific small molecule DUB inhibitor N-ethylmaleimide was 16.2+/-3.2 muM and can be used as a q

295 The thiol-blocking agent N-ethylmaleimide was applied in order to inhibit formation

296 bitor (vanadate) and a sulfyhdryl reagent (N-ethylmaleimide) was determined.

297 minoethyl methanethiosulfonate, but not by N-ethylmaleimide, was fully protected in the presence of s

298 the kinase inhibitor staurosporine and by N-ethylmaleimide, whereas KCC2(WT), KCC2(T934A), and KCC2(

299 ion of its only free cysteine residue with N-ethylmaleimide), which causes significant reduction in i

300 ith either 20mM added NaCl (WPI+NaCl), 5mM N-ethylmaleimide (WPI+NEM) or 20mM added NaCl and 5mM NEM