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1 led that VZV ORFs 62, 63, 36, and 14 are all euchromatic.
2 romatic, and in D2, the transgene has become euchromatic.
3 o the more distal regions, which are largely euchromatic.
4 e's "inaccessible" regions: sequences (often euchromatic and containing genes) that are isolated from
5 omatic and gene poor, the mouse MSY is 99.9% euchromatic and contains about 700 protein-coding genes.
8 and paired RNAs are strongly correlated with euchromatic and heterochromatic epigenetic histone modif
10 termination of lncRNA transcription in both euchromatic and heterochromatic lncRNA-based gene silenc
12 family of Drosophila melanogaster, which has euchromatic and heterochromatic members, we find that pr
13 n was supported by its reciprocal effects on euchromatic and heterochromatic PEV; E(var)3-9 mutations
14 eveals structural properties associated with euchromatic and heterochromatic regions in the genome.
15 study changes of chromatin accessibility in euchromatic and heterochromatic regions under extended d
16 ions, including overrepresentation of MSI in euchromatic and intronic regions compared to heterochrom
19 equences that can be mapped to the assembled euchromatic arms, we identified sequences that are speci
23 tion of heterochromatic satellite DNA in the euchromatic brown (bw) gene of Drosophila melanogaster r
24 ls, but not CD177(neg) neutrophils, showed a euchromatic CD177 promoter, unmethylated CpGs, and c-Jun
25 observations suggest that Piwi promotes the euchromatic character of 3R-TAS heterochromatin and its
26 ous component of rice CEN chromatin, and the euchromatic characteristics of rice CEN chromatin are ha
28 eukaryotes, but, interestingly, it can show euchromatic characteristics; for example, the euchromati
29 g a functional role for JIL-1 in maintaining euchromatic chromatin and counteracting heterochromatic
30 osophila phosphorylation of histone H3S10 in euchromatic chromatin regions by the JIL-1 tandem kinase
31 of PEV, suggesting a role for the protein in euchromatic chromatin structure and/or transcription.
33 ysis of eight "wanderer" genes (present in a euchromatic chromosome arm in one species and on the dot
34 xpectedly large fraction of sequences in the euchromatic chromosome arms exhibits a heterochromatic c
35 SMC4/condensin also acts within the mostly euchromatic chromosome arms to suppress conditionally ex
39 hat signal-induced nuclear translocation and euchromatic compartmentalization constitute an additiona
41 the locations of FM7 breakpoints to precise euchromatic coordinates and identified the flanking sequ
42 is sufficient to locally silence Arabidopsis euchromatic crossover hot spots and is associated with i
44 histone methyltransferase that catalyzes the euchromatic dimethylation of histone H3 at lysine 9 (H3K
46 datively induced DSBs arise in HC as well as euchromatic DNA and that Artemis and ATM function in the
47 rosophila species, provide information about euchromatic DNA content, they cannot give an accurate es
49 ight palindromes comprise one-quarter of the euchromatic DNA of the male-specific region of the human
51 spatially associated with early replicating, euchromatic DNA, which is predominately found in distal
58 romatin structure that functions to maintain euchromatic domains while counteracting heterochromatiza
59 structure and that it functions to maintain euchromatic domains while counteracting heterochromatiza
60 ve sites were identified, some in apparently euchromatic domains, although all are close to heterochr
61 ic properties (e.g., gene density similar to euchromatic domains, replication during polytenization).
63 7me3 occurs in a few (roughly seven) focused euchromatic domains; (5) centromeres and CENP-C are clos
64 DSBs are generally repaired more slowly than euchromatic DSBs, and ATM signaling is specifically requ
66 located within transcriptionally permissive euchromatic environments, and promote deposition of hist
68 s, closes 105 and extends into 72 out of 190 euchromatic gaps in the reference genome, adding 1.03 Mb
70 malian reference assembly, yet more than 160 euchromatic gaps remain and aspects of its structural va
71 equence, 363,114 bp of which close 26 of 250 euchromatic gaps, or 10%, including two remaining euchro
77 -marked chromomeres, clearly demarcating the euchromatic gene space; (3) H3K9me2 is restricted to the
78 gene space; (3) H3K9me2 is restricted to the euchromatic gene space; (4) H3K27me3 occurs in a few (ro
79 ased H3K9 methylation accompanied by reduced euchromatic gene transcription and heterochromatin propa
80 transition region structure originates from euchromatic gene-containing segments of DNA that were du
82 ughout all heterochromatic loci and inactive euchromatic genes and is present at the 3' end of modera
83 taneously involved in both the repression of euchromatic genes brought to the vicinity of pericentric
84 topic association of silencing proteins with euchromatic genes important for cell wall integrity and
86 Genetic studies of rearrangements that place euchromatic genes next to blocks of heterochromatin also
90 argely conserved between heterochromatic and euchromatic genes, eliminating the hypothesis that adapt
91 elements (MITEs) are closely associated with euchromatic genes, the broader functional impact of thes
92 inary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylat
93 anscriptome analysis, we identified a set of euchromatic genes-enriched in those required for the cel
98 Notably, we found that virtually the entire euchromatic genome (including intergenics) is transcribe
99 enes) that are isolated from the rest of the euchromatic genome by heterochromatin and other repeat-r
102 third chromosome ( approximately 36% of the euchromatic genome) for suppressor mutations of piwi2 an
106 ate that the fraction of the human and mouse euchromatic genomes encoding lincRNAs is more than twofo
108 accessibility to DNase I and an induction of euchromatic H3 and H4 histone acetylations upon nicotina
110 This analysis revealed the pervasive loss of euchromatic H3K9me2 as a conserved feature of pathologic
113 DM4A (dKDM4A), previously characterized as a euchromatic histone H3 K36 demethylase and transcription
115 0638 and UNC0642-two selective inhibitors of euchromatic histone lysine N-methyltransferase-2 (EHMT2,
116 s of histone acetylation, whereas removal of euchromatic histone methylation occurs gradually through
117 hylation of H3-K9 by the recently identified euchromatic histone methyltransferase SETDB1/ESET may be
119 eveals that LSD2 forms active complexes with euchromatic histone methyltransferases G9a and NSD3 as w
120 of LMP1 and LMP2A correlated with a loss of euchromatic histone modification H3K9ac and a correspond
121 As shown by chromatin immunoprecipitation, euchromatic histone modification H3K9ac is added at prom
122 uchromatic characteristics; for example, the euchromatic histone modification mark dimethylated H3 Ly
123 ipitation-chip to study the patterns of four euchromatic histone modification marks: H3K4me2, trimeth
125 e 3R-TAS1 piRNA coding sequence restores the euchromatic histone modifications of 3R-TAS and the expr
126 on in the absence of HDA6 activity; instead, euchromatic histone modifications typical of active gene
131 ased H3K9me2/3 in CIITA via up-regulation of euchromatic histone-lysine N-methyltransferase 2 (G9a).
135 al analysis is undertaken to verify that the euchromatic human genome is sufficiently complete--conta
138 M1 and the DNA methyltransferase MET1 of the euchromatic, imprinted gene FWA, as its promoter is prov
140 nase in Drosophila localizes specifically to euchromatic interband regions of polytene chromosomes an
141 Early S nuclei exhibited widely distributed euchromatic labeling preferentially localized to regions
142 e S nuclei also exhibited widely distributed euchromatic labeling, but the label was preferentially l
143 te that P-Ser 83-HP1gamma has an exclusively euchromatic localization, interacts with Ku70 (a regulat
146 The activity of each promoter construct in euchromatic locations is also generally consistent with
147 HeT-A promoter constructs are active in all euchromatic locations tested and some display aspects of
149 ibution of SIRT1 to epigenetic regulation at euchromatic loci and whether it acts in concert with oth
150 To characterize the physical properties of euchromatic loci bound by HP1, we developed a strategy f
153 ngle DSB system for both heterochromatic and euchromatic loci in Drosophila melanogaster Live imaging
154 that tethering Clr4 via DNA-binding sites at euchromatic loci induces heterochromatin assembly, with
155 ncing proteins and discovered 238 unexpected euchromatic loci that exhibited enrichment of all three.
156 lso precludes nucleosome turnover at several euchromatic loci to prevent R-loop formation, ensuring p
157 ilencing complex that is also distributed at euchromatic loci, and with RNA interference component Ar
158 so mediates degradation of antisense RNAs at euchromatic loci, but the underlying mechanism has remai
162 e3 and DNA methylation at a normally active, euchromatic locus but did not bypass the requirement of
165 Strikingly, 90% to 95% of the total genomic euchromatic marks histone H3 acetylated at lysine 9 and
166 er per physical length over the distal first euchromatic megabase pairs of the X chromosome, our data
168 r the recruitment of G9a, the main mammalian euchromatic methyltransferase, and defines nonembryonic
170 localize to a largely non-overlapping set of euchromatic nuclear speckles, suggesting that Set1A and
171 Cerebellar Purkinje neurons have large and euchromatic nuclei, whereas granule cell nuclei are smal
176 n RNAi-dependent H3K9 methylation of several euchromatic pockets, prior to which Argonaute1-associate
178 oding DNA comprises approximately 80% of the euchromatic portion of the Drosophila melanogaster genom
179 ed improvement of the 117-Mb sequence in the euchromatic portion of the genome and 21 Mb in the heter
180 ial and approximately equal fractions of the euchromatic portion of the genome are inferred to contri
183 anscriptional, and chromatin features of the euchromatic portion of the maize genome provide evidence
185 locus is similar to that described in other euchromatic portions of the tomato genome despite the re
186 rosophila, recruitment of mammalian HP1 to a euchromatic promoter can establish a silenced state that
187 eterochromatic genes are very different from euchromatic promoters, but this idea has not been tested
188 e.g., dense packaging, late replication) and euchromatic properties (e.g., gene density similar to eu
190 chromatin structure, and the high levels of euchromatic rDNA induced by the BBDS mutations direct nu
192 es indicated that in juvenile-stage rice the euchromatic region is more actively transcribed than is
193 a 200 copy transgene array integrated into a euchromatic region of chromosome 1 in human U2OS cells.
197 itical in obtaining complete sequence of the euchromatic region of the horse Y chromosome, with an ai
199 molecular markers and a linkage map for the euchromatic region of the Syrian hamster X chromosome th
202 e of methylation on meiotic recombination in euchromatic regions and suggests that additional factors
203 hila endocycle, heterochromatin and specific euchromatic regions are underreplicated and reduced in c
204 ng high levels of homolog pairing at all six euchromatic regions assayed and variably lower levels in
205 JIL-1 kinase activity functions to maintain euchromatic regions by antagonizing Su(var)3-9-mediated
206 erochromatin from spreading into neighboring euchromatic regions by recruiting transcription factor T
207 enabled localization of heterochromatic and euchromatic regions for each chromosome of both species.
208 ricentromeres and transformed large formerly euchromatic regions into repeat-rich pericentromeric reg
209 repeat sequences, yet with 30% more compact euchromatic regions it is the smallest known grass genom
210 ses correct in reconstructing megabase-scale euchromatic regions of an eutherian ancestral genome fro
212 es "ectopic heterochromatin" at sites within euchromatic regions of the Drosophila melanogaster genom
213 ARP-1-dependent Sox2-binding sites reside in euchromatic regions of the genome with relatively high n
214 mediated effects occurring throughout active euchromatic regions of the genome, with very little know
218 ptionally inert relative to the more typical euchromatic regions that decondense during interphase.
220 ocal repatterning of hominoid chromosomes in euchromatic regions through a duplication-driven mechani
222 we show that MLL5 is recruited to gene-rich euchromatic regions via the interaction of its plant hom
223 tic recombination between markers located in euchromatic regions was significantly higher in both het
224 ciated significantly more often than average euchromatic regions with heterochromatic chromocenters (
225 hese proteins were also enriched in the same euchromatic regions with the high Sir protein levels.
227 including those typically found in gene-rich euchromatic regions, lose DNA methylation in a mutant la
228 n ectopic spreading of H3K9me2 into adjacent euchromatic regions, mimicking the phenotype observed in
229 as methylated in low-turnover nucleosomes in euchromatic regions, notably in the coding regions of lo
230 ta cells, Sir2 and Sir3 spread into flanking euchromatic regions, producing changes in histone H4 ace
237 repeat (180-bp knob sequence) or an abundant euchromatic retroelement (Opie) are undetectable within
238 k1, a core subunit of the CLRC complex, to a euchromatic RNA mediates RNAi-dependent silencing that p
239 gamma-H2AX, by comparing HR occurring at the euchromatic ROSA26 locus between mouse embryonic stem ce
244 es; these findings are in marked contrast to euchromatic segments in these species that exhibit only
247 e nucleotide polymorphism in the most distal euchromatic sequence are approximately one order of magn
248 ed telomeric deficiencies cause deletions of euchromatic sequence followed by subsequent "healing" by
249 million base pairs representing 99.4% of the euchromatic sequence of chromosome 7, the first metacent
253 we report 2,488,842 bp of previously unknown euchromatic sequence, 363,114 bp of which close 26 of 25
254 aster genome, with the most recent update of euchromatic sequence, gives the first genome-wide view o
255 on base pairs of the human genome's unplaced euchromatic sequence, including more than a dozen protei
257 bstitutional patterns in heterochromatic and euchromatic sequences are different, but also they provi
259 rmed by this localization of genes and other euchromatic sequences that are embedded within highly re
260 evels of trimethyl H3K9 or the repression of euchromatic sequences were not affected by SET3 downregu
263 terochromatic sequences and three classes of euchromatic sequences: X-transposed, X-degenerate and am
264 ect largely completed the detailing of human euchromatic sequences; however, the most highly repetiti
266 ng that this histone variant is required for euchromatic silencing and heterochromatin formation.
267 ut angiosperms in gene body DNA methylation, euchromatic silencing of transposons and repeats, as wel
270 observed broadly distributed throughout all euchromatic sites analyzed, with selective depletion in
271 -4 methylation prevents Sir3p association at euchromatic sites and therefore concentrates Sir3p at un
273 ly assumed that these sites might constitute euchromatic sites of transcriptional repression by HP1.
275 ea mays (maize) minichromosomes derived from euchromatic sites with high-density gene distributions b
276 Sir3 also bound to a surprising number of euchromatic sites, largely at genes expressed at high le
277 ing with Taz1 and the RNAi machinery, and to euchromatic sites, via mechanism(s) distinct from its he
282 noprecipitation (ChIP) assays to analyze the euchromatic state of ORFs 62 and 63 compared to the cent
285 We resolve the complete sequence of 26,079 euchromatic structural variants at the base-pair level,
288 demonstrates that the epigenetic effects of euchromatic TEs, and host genetic factors modulating suc
289 Greater microcolinearity in recombinogenic (euchromatic) than nonrecombinogenic (heterochromatic) re
290 ls or genomic regions that switched from the euchromatic to the heterochromatic compartment during ne
291 n regulating heterochromatin propagation and euchromatic transcription and also suggest that misregul
292 ctive, contain modifications associated with euchromatic transcription, and couple RNAi-mediated tran
295 Still mysterious though is how Piwi targets euchromatic transposons for silencing, but not the speci
296 piRNA loci interact with potentially active, euchromatic transposons to form an adaptive system for t
299 aldehyde-3-phosphate dehydrogenase promoter (euchromatic), we show that the promoters of ORFs 62 and
300 ction of pachytene chromosome length that is euchromatic, we estimate that approximately 1500 Mbp of
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