ライフサイエンスコーパス: euchromatin

1 educed histone modifications associated with euchromatin.

2 tionally inactive heterochromatin and active euchromatin.

3 d by its C-terminal domain to nucleosomes in euchromatin.

4 into distinct domains of heterochromatin or euchromatin.

5 y be distinct from either heterochromatin or euchromatin.

6 romatin, whereas H3K4 methylation demarcates euchromatin.

7 spreading of silent chromatin into proximal euchromatin.

8 ized with acetylated histone H3, a marker of euchromatin.

9 transition from telomeric heterochromatin to euchromatin.

10 ansion of silent chromatin into neighbouring euchromatin.

11 on, a modification typically associated with euchromatin.

12 an average spacing of <14 kb across the MSY euchromatin.

13 silent mating-type locus HMRa into flanking euchromatin.

14 ericentromeric heterochromatin, and flanking euchromatin.

15 in rearrangements and insertions uncommon in euchromatin.

16 stone acetylation patterns characteristic of euchromatin.

17 nsitional states between heterochromatin and euchromatin.

18 1.4 times higher in heterochromatin than in euchromatin.

19 d at promoter regions of nearly all genes in euchromatin.

20 erochromatin and some repressed genes within euchromatin.

21 oximately 1500 Mbp of the maize genome is in euchromatin.

22 perating as an epigenetic mark for repressed euchromatin.

23 localize to nuclear speckles associated with euchromatin.

24 E annotations in the Drosophila melanogaster euchromatin.

25 y are located distally on the chromosomes in euchromatin.

26 parison with the same transgene construct in euchromatin.

27 16 sequence, representing over 99.9% of its euchromatin.

28 dary between pericentric heterochromatin and euchromatin.

29 methylation of H3-K9 and localizes mainly in euchromatin.

30 alized specifically to silent domains within euchromatin.

31 constitutive heterochromatin and unexpressed euchromatin.

32 nsfection but repressed promoter activity in euchromatin.

33 different parts of the putative promoter in euchromatin.

34 e than LEDGF/p75 in directing integration to euchromatin.

35 rays to an average of 30% of the staining in euchromatin.

36 cant amount of monomethylation within silent euchromatin.

37 rth chromosome, and to specific sites within euchromatin.

38 human genomes were found within interstitial euchromatin.

39 lly account for the preservation of adjacent euchromatin.

40 ired for the acetylation (Ac) of H4-Lys16 in euchromatin.

41 ic heterochromatin, rather than telomeres or euchromatin.

42 g heterochromatin structure into neighboring euchromatin.

43 omatin and HP1c is restricted exclusively to euchromatin.

44 of acetylation sites in heterochromatin and euchromatin.

45 mark the borders between heterochromatin and euchromatin.

46 romatin, (2) centric heterochromatin, or (3) euchromatin.

47 te away from heterochromatin compartments to euchromatin.

48 ere integrated to produce a map spanning the euchromatin.

49 loop extends into the nucleoplasm to contact euchromatin.

50 32 and hHP1gamma, both of which are found in euchromatin.

51 egular nucleosome array than when located in euchromatin.

52 ates with H2A.Z to evict CENP-A assembled in euchromatin.

53 mily also associate with repressed states of euchromatin.

54 hat restricts transcription to gene units in euchromatin.

55 (Cse4) ubiquitylation and its exclusion from euchromatin.

56 is differentially processed within hetero or euchromatin.

57 DNA damage in heterochromatin, as well as in euchromatin.

58 tion-resistant heterochromatin (srHC) versus euchromatin.

59 ome or about 78 % of the estimated 252 Mb of euchromatin.

60 ats are packaged into Xi-specific CTCF-bound euchromatin.

61 access only to lineage-specific genes in the euchromatin.

62 ing global histone acetylation and retaining euchromatin.

63 thway-specific control of gene expression in euchromatin.

64 at the junctions between heterochromatin and euchromatin.

65 tion (HR) but with striking differences from euchromatin.

66 repeat (TR) sequences in both telomeres and euchromatin.

67 ay differential roles in heterochromatin and euchromatin.

68 In euchromatin, 1360 is not sufficient to induce silencing,

69 ssregulation of H3K4 and H3K9 methylation in euchromatin also requires Lid2.

70 d, these elements are entirely excluded from euchromatin, although sequence fragments of HeT-A and TA

71 ir acetylation pattern from those present in euchromatin, although the role these differences play in

72 Euchromatin analysis revealed that the LAT-ICP0 locus is

73 lysine acetylation, normally associated with euchromatin and active genes, is regulated by different

74 density 10-100 times lower than that of the euchromatin and are heavily populated by retrotransposon

75 than half of the transition regions between euchromatin and centromeric heterochromatin contain dupl

76 ed in more increased chromatin compaction in euchromatin and decompaction in heterochromatin, thus fu

77 nd inactive (Xi) X chromosomes packaged into euchromatin and facultative heterochromatin.

78 Dt-to-At conversion is abundant in euchromatin and genes, frequently reversing losses of ge

79 lysis of repair products reveal that DSBs in euchromatin and heterochromatin are repaired with simila

80 er, chromosome rearrangements that juxtapose euchromatin and heterochromatin can result in position e

81 Thus, euchromatin and heterochromatin each contains components

82 GAGA factor suggests that they cycle between euchromatin and heterochromatin independently.

83 Thus, the transition between euchromatin and heterochromatin is gradual and requires

84 ion protein is highly mobile within both the euchromatin and heterochromatin of ex vivo resting murin

85 mine differences in the accessibility of the euchromatin and heterochromatin regions of the epigenome

86 he spatial organization of epigenetic marks, euchromatin and heterochromatin, and origins of replicat

87 histone H3 at lysine 9, which are marks for euchromatin and heterochromatin, respectively.

88 ggesting a disruption of the balance between euchromatin and heterochromatin.

89 omatin domains but binds only transiently to euchromatin and heterochromatin.

90 iption state change and heritability at both euchromatin and heterochromatin.

91 they contribute differentially to binding in euchromatin and heterochromatin.

92 n exchange events is several minutes in both euchromatin and heterochromatin.

93 ate chromatin state bearing features of both euchromatin and heterochromatin.

94 thin intergenic regions and at the border of euchromatin and heterochromatin.

95 somes is highly conserved and occurs at both euchromatin and heterochromatin.

96 tic genomes are packaged in two basic forms, euchromatin and heterochromatin.

97 , HP1b localizes to both heterochromatin and euchromatin and HP1c is restricted exclusively to euchro

98 s are organized into active regions known as euchromatin and inactive regions known as heterochromati

99 tively specified malignant traits, including euchromatin and large organized chromatin histone H3 lys

100 a, IL-33 localized simultaneously to nuclear euchromatin and membrane-bound cytoplasmic vesicles.

101 ectural protein that binds preferentially to euchromatin and modulates the fidelity of the cellular t

102 ymphoid cells were like those in unexpressed euchromatin and not constitutive heterochromatin.

103 sights into the compositional differences of euchromatin and pericentromeric heterochromatin in this

104 Distal regions of euchromatin and pericentromeric regions of heterochromat

105 ologues (MRG1 and MRG2) are localised to the euchromatin and redundantly ensure the increased transcr

106 on of histones can alter the balance between euchromatin and silenced chromatin within a cell.

107 distinct domains of transcriptionally active euchromatin and silent heterochromatin.

108 We find that 5hmC is mostly associated with euchromatin and that whereas 5mC is under-represented at

109 enomes are broadly divided between gene-rich euchromatin and the highly repetitive heterochromatin do

110 me segregation into transcriptionally active euchromatin and transcriptionally repressed heterochroma

111 nts correspond to cytologically discernible "euchromatin" and "heterochromatin." Gene and repetitive

112 chromosome ends, (ii) they are not found in euchromatin, and (iii) they produce both sense and antis

113 G9a methylates H3-K9 in euchromatin, and G9a null embryos die at 8.5 days postco

114 for modifications that define CEN chromatin, euchromatin, and heterochromatin.

115 istal 1.2 Mb, the gene density is typical of euchromatin, and this region is polytene in salivary gla

116 ng DNA replication, both heterochromatin and euchromatin are disrupted ahead of the replication fork

117 These interactions of heterochromatin and euchromatin are likely to have important roles in modula

118 ggest that widespread interactions along the euchromatin are required for the initiation, but not the

119 This uniformity made it possible to use euchromatin as a control for quantitative staining inten

120 ruitment that is embedded within a region of euchromatin-associated H3 lysine 4 (H3-K4) methylation.

121 In cells lacking the euchromatin-associated histone variant H2A.Z, BRE1, RAD6

122 heterochromatin-associated modifications to euchromatin-associated modifications.

123 ed) DNA probes detects surprisingly abundant euchromatin-associated RNA comprised predominantly of re

124 modified histones demonstrate that gene-rich euchromatin associates with the LA/C blebs.

125 splayed a localization pattern suggestive of euchromatin association.

126 isiae, histone variant H2A.Z is deposited in euchromatin at the flanks of silent heterochromatin to p

127 to the epigenetic balance of heterochromatin/euchromatin at three distinct loci showing position-effe

128 other histone modifications associated with euchromatin, at the insulator.

129 ribe the draft sequence of the M. truncatula euchromatin based on a recently completed BAC assembly s

130 These observations suggest that euchromatin begins to condense during late S phase and t

131 The tuh-1 locus is located at the euchromatin-beta-heterochromatin junction near the centr

132 t relative distance (percent of SC length in euchromatin) between two foci on SCs of different length

133 X chromosome, inactivation is organized into euchromatin bound by the insulator protein CCCTC-binding

134 the epigenetic regulation of heterochromatin/euchromatin boundaries by Lid and dLsd1 and showing thei

135 gulation of genes located at heterochromatin-euchromatin boundaries.

136 heterochromatin spreading at heterochromatin-euchromatin boundaries.

137 mutants dramatically shift a heterochromatin-euchromatin boundary in Chr1, suggesting a novel role in

138 K9 methylation levels at the heterochromatin-euchromatin boundary.

139 e unique classes: (I) those that localize to euchromatin but do not alter kinetochore function, (II)

140 me and the reduction of RNA polymerase II in euchromatin but its increase in pericentric regions in p

141 cell lines and found that AGO2 localizes to euchromatin but not heterochromatin.

142 n Arabidopsis, H3K36ac is highly enriched in euchromatin but not in heterochromatin.

143 to the histone modifications associated with euchromatin but not to the heterochromatic mark of methy

144 TC exposure not only blocked HDAC binding to euchromatin but was also associated with hypomethylation

145 oaches have been applied successfully to the euchromatin, but analysis of the heterochromatin has lag

146 e highly undercondensed, particularly in the euchromatin, but nevertheless contain phosphorylated his

147 udding yeast CENP-A(Cse4) mislocalization to euchromatin by mediating its proteolysis.

148 Polycomb regions and the rest of the euchromatin can be connected by two major chromatin path

149 Other less extensive bands of euchromatin can be observed on the Xi, but the identity

150 e (Xi) a proportion of DXZ4 is packaged into euchromatin characterized by H3K4me2 and H3K9Ac.

151 mes, EST density is about fourfold higher in euchromatin compared with heterochromatin, while DNA den

152 irmed the presence of dense RGS10-LIR in the euchromatin compartment of nuclei.

153 eas the larger subunit NF-E2p45 occupies the euchromatin compartment.

154 transcriptional repressors, relocates to the euchromatin compartment.

155 Thus, while the euchromatin comprises only 25% of the tomato nuclear DNA

156 The second fraction is euchromatin confined to distal chromosome segments, posi

157 n and topo II colocalize along both rDNA and euchromatin, consistent with coordination of their activ

158 oss of repeat-rich, stable nuclear RNAs from euchromatin corresponds to aberrant chromatin distributi

159 opic pericentric heterochromatin embedded in euchromatin display additional cohesin-dependent constri

160 For insertions in euchromatin, DNA access is the primary determinant of ta

161 heterochromatin states from the rest of the euchromatin domains.

162 from constitutive heterochromatin (cHC) and euchromatin (EC) and discusses various concepts regardin

163 g that controlled by H2AX, in the context of euchromatin, excluding the implication of such an HR fun

164 h the abnormally late replicating regions of euchromatin exhibiting the greatest problems in mitotic

165 These results revealed that maize euchromatin exists as an intermingled mixture of two com

166 stitutive heterochromatin and stably active, euchromatin, facultative heterochromatin has the capacit

167 ns through histone modifications and altered euchromatin formation, leading to the persistence and pa

168 th the role of hyperacetylation in promoting euchromatin formation.

169 redundant mechanisms to demarcate regions of euchromatin from heterochromatin.

170 emodeling complex (Ino80C) directly prevents euchromatin from invading transcriptionally silent chrom

171 ing domain and a Gal4-reporter integrated in euchromatin, Gal4-SirT1 expression resulted in the deace

172 K9) has recently been shown to contribute to euchromatin gene silencing.

173 The results indicate that tomato euchromatin has a gene density (6.7 kb/gene) similar to

174 ed is representative, we estimate that human euchromatin has expanded 30 Mb and 550 Mb compared to th

175 Unlike the more gene-rich euchromatin, heterochromatin remains condensed during in

176 The locations of the euchromatin-heterochromatin borders identified by these

177 f1p functions to restrict silencing at yeast euchromatin-heterochromatin boundaries; therefore we del

178 Indeed, genes located proximal to the euchromatin-heterochromatin boundary of the X chromosome

179 s response to small extensions (<3 mum), and euchromatin/heterochromatin levels modulate the stiffnes

180 We suggest that overlapping euchromatin/heterochromatin marks are common and are enr

181 rozygous mutations or deletions of the human Euchromatin Histone Methyltransferase 1 (EHMT1) gene are

182 The euchromatin histone methyltransferase 2 (also known as G

183 rlapping marks in the genome related to both euchromatin (histone H3 dimethyl lysine-4 [H3K4Me2]) and

184 nactive X chromosome usually associated with euchromatin: histone H4 acetylation and histone H3 lysin

185 alpha locus migrates from heterochromatin to euchromatin in a progressive fashion, reaching euchromat

186 hment of the chromatin remodeler, PICKLE, at euchromatin in Arabidopsis thaliana.

187 PARP is largely absent from euchromatin in PARG mutants, but accumulates in large nu

188 preads from heterochromatin into neighboring euchromatin in set2Delta cells.

189 tes to a balance between heterochromatin and euchromatin in the nucleus, and alterations in rDNA--ind

190 ning the balance between heterochromatin and euchromatin in vivo.

191 e human genome in regulating global cellular euchromatin, including that of intergenic regions.

192 se proteins bind numerous dispersed sites in euchromatin, indicating that they move from euchromatin

193 , that might include altered heterochromatin-euchromatin interactions, may be important consequences

194 nces of genes located at the heterochromatin:euchromatin interface, with a very strong correlation be

195 cture, but the kinetics and pathway by which euchromatin is converted to the stable heterochromatin s

196 gram of asynchronous endocycles in which the euchromatin is entirely replicated, and then confine DNA

197 cription factors (TFs) to repressed genes in euchromatin is essential to activate new transcriptional

198 In the nuclei of eukaryotic cells, euchromatin is located at the center, whereas heterochro

199 Surprisingly, DNase-accessible euchromatin is protected from UV, while lamina-associate

200 We suggest that Lid2 enzymatic activity in euchromatin is regulated through a dynamic interplay wit

201 DNA can be packaged in two distinct forms: euchromatin is relatively accessible to DNA binding prot

202 We furthermore show that euchromatin islands, local regions of active chromatin w

203 nuclear RNAi, MET-1-mediated encroachment of euchromatin leads to detrimental decondensation of germl

204 stinct regions of the genome are packaged as euchromatin (less condensed, more active) or heterochrom

205 regions and their adjacent unique gene-rich euchromatin-like regions.

206 interactions and is sufficient to generate a euchromatin-like state.

207 chromosome clones shows that the R domains (euchromatin-like) and V domains (heterochromatin-like) a

208 chromo shadow domain is implicated solely in euchromatin localization.

209 hese data suggest an active role for Bdf1 in euchromatin maintenance and antisilencing through a hist

210 esses, including transcriptional activation, euchromatin maintenance, and heterochromatin formation.

211 ptional activation of RBP2 targets linked to euchromatin maintenance.

212 onded to a two- to threefold increase in the euchromatin marker histone H3 dimethyl-Lys4 at their res

213 hird, a poor correlation is observed between euchromatin marks (H3-K9/K14Ac, H3-K4Me2, H3-K36Me2, and

214 f heterochromatin marks and the reduction of euchromatin marks on viral chromatin at both early and l

215 f heterochromatin marks and the reduction of euchromatin marks on viral chromatin.

216 iation of polycomb proteins, and presence of euchromatin marks within the respective promoters.

217 dicative of its predominant interaction with euchromatin, MCAP localized on mitotic chromosomes with

218 Further, Snail interacted with G9a, a major euchromatin methyltransferase responsible for H3K9me2, a

219 factor and Prod from high affinity sites in euchromatin occurs upon condensation of metaphase chromo

220 rom radius) spots in the heterochromatin and euchromatin of cells of both types.

221 ociated with hundreds of chromosomal loci in euchromatin of salivary gland polytene chromosomes, howe

222 ding regions of active genes, constitute the euchromatin of the nuclear interior.

223 croscopy showed that OGT is localized to the euchromatin of the nucleus and around the secretory gran

224 e H3 (H3 Lys4) has been found in expressible euchromatin of yeasts and mammals.

225 tion from pericentromeric heterochromatin to euchromatin on the long arm of this chromosome.

226 e transition from centric heterochromatin to euchromatin on this chromosome arm.

227 regions depending on the presence of either euchromatin or heterochromatin.

228 h histone deacetylase inhibitors to increase euchromatin or histone methyltransferase inhibitors to d

229 ochromatin and is not affected by homologous euchromatin or overall size differences.

230 oding preproinsulin, requires an appropriate euchromatin (or "open") DNA template characterized by hy

231 er to active (or inactive) compartments like euchromatin (or heterochromatin), and this is usually as

232 ct of huntingtin function in heterochromatin/euchromatin organization is evolutionarily conserved acr

233 ustrate the dynamic chromatin changes during euchromatin-originated de novo centromere formation, whi

234 We conclude that patterns of heterochromatin/euchromatin packaging show greater complexity and plasti

235 matin patterns reveals distinct profiles for euchromatin, pericentric heterochromatin, and the 4th ch

236 finished sequence representing 99.9% of the euchromatin portion of the chromosome.

237 Transcriptionally permissive euchromatin predominates during lytic infection, whereas

238 ne H2A with the histone variant H2A.Z within euchromatin prevents silent chromatin proteins from migr

239 Here, we investigated heterochromatin and euchromatin profiles of the entire fission yeast genome

240 lete DNA replication; poorly banded polytene euchromatin progressively condenses during the late S ph

241 However, thousands of loci in euchromatin progressively lose DNA methylation between g

242 Chd1 is a euchromatin protein that associates with the promoters o

243 centromeric repeat arrays interspersing the euchromatin provides a previously unidentified type of c

244 cleus, PGC-1alpha was associated mainly with euchromatin rather than heterochromatin, consistent with

245 hanges that enhance meiotic recombination in euchromatin regions but are not sufficient to induce the

246 nce a nearby gene, how gene silencing within euchromatin regions is achieved remains elusive.

247 nding of Sir3p, and Sir4p at telomere-distal euchromatin regions, correlating with decreased gene exp

248 patterns in the human genome, especially in euchromatin regions, have not been systematically charac

249 olysis prevents CENP-A from mislocalizing to euchromatin, regulatory factors have not been identified

250 s or by selection against TE insertions into euchromatin remains obscure.

251 ring S-phase progression in wild-type cells, euchromatin replicates early and heterochromatin replica

252 was used to induce ROS damage in hetero- or euchromatin, respectively.

253 neration of facultative heterochromatin from euchromatin reversibly silences transcription of a set o

254 cluding the recruitment of promoter regions, euchromatin-rich domains, and differentially expressed g

255 hted by concentrations in axon terminals and euchromatin-rich nuclear domains.

256 ight coverage capturing approximately 65% of euchromatin sequence from the cat genome, these comparat

257 chromatin in a progressive fashion, reaching euchromatin slightly later in differentiation.

258 nt protein fusion genes in Drosophila cells, euchromatin-specific deposition results.

259 responsible for heterochromatin-specific and euchromatin-specific localization.

260 function, likely through the maintenance of euchromatin structure at genes necessary for glucose-sti

261 res present on the latent provirus to active euchromatin structures containing acetylated histones.

262 The Cse4-351 protein localized to euchromatin, suggesting that proteolysis prevents CenH3

263 istone modification patterns consistent with euchromatin, suggesting that rice centromeric chromatin

264 chromatin structure appeared more similar to euchromatin than to heterochromatin.

265 potent ability to regulate large domains of euchromatin than to influence the transcription of indiv

266 euchromatin, indicating that they move from euchromatin to heterochromatin and back every cell cycle

267 sistent with the model of FMR1's switch from euchromatin to heterochromatin in the disease state.

268 olutionary transition of a gene cluster from euchromatin to heterochromatin, which occurred <20 milli

269 p65, and induces a sustained switch from the euchromatin to heterochromatin.

270 bursts of duplicative transposition from the euchromatin to pericentromeric regions.

271 e facultative heterochromatin from impinging euchromatin to produce discrete positional identities.

272 SCL2, indicating that JHDM3A may function in euchromatin to remove histone methylation marks that are

273 protein kinase that associates tightly with euchromatin, to analyze the properties of the BrD in a n

274 experience selective pressures distinct from euchromatin, tolerating rapid, dynamic changes in struct

275 hat remains condensed in interphase, whereas euchromatin undergoes de-condensation.

276 tion to its previously characterized role in euchromatin, utilizes both enzymatic and structural mech

277 n through a Sir3-stimulated mechanism and to euchromatin via a TBP-stimulated mechanism.

278 of Cse4 by preventing its mislocalization to euchromatin via Psh1-mediated degradation.

279 Heterochromatin/euchromatin was previously estimated from molecular mobi

280 Retroelement staining in euchromatin was remarkably uniform, even when we include

281 le short contigs encompassing 85% or more of euchromatin, was announced in June of 2000.

282 Histone H3 methylated at Lys4, which defines euchromatin, was not only distributed across most of the

283 Large-scale variant features in euchromatin were identified with periodicities of approx

284 ol I and pol II transcribed genes located in euchromatin were shown to have levels of H4 acetylation

285 whether they occurred in heterochromatin or euchromatin, were strongly associated with DNase hyperse

286 These genes normally reside in euchromatin where GAGA factor and RNA Pol II are present

287 includes large regions (about 30% of the MSY euchromatin) where sequence pairs show greater than 99.9

288 inding directs HIV-1 to actively transcribed euchromatin, where the integrase-LEDGF/p75 interaction d

289 k-inducible activity similar to that seen in euchromatin, whereas in the latter case, accessibility a

290 pression of CENP-A causes mislocalization to euchromatin, which could lead to deleterious consequence

291 Euchromatin, which has an open structure and is frequent

292 karyotic cells, chromatin is classified into euchromatin, which is active in transcription, and heter

293 ed crossover increases occur in subtelomeric euchromatin, which is reminiscent of sex differences in

294 is packaged as transcriptionally permissive euchromatin with few loci embedded in silenced heterochr

295 eterochromatin segment in juxtaposition with euchromatin without affecting the epigenetic landscape.