ライフサイエンスコーパス: eukaryote

1 wnstream signaling events in a multicellular eukaryote.

2 ncRNAs might act as an adaptive reservoir in eukaryotes.

3 in-based symmetry-breaking systems of higher eukaryotes.

4 ultiplex combinatorial genome engineering in eukaryotes.

5 es virtually every known cellular process in eukaryotes.

6 ostasis of the endoplasmic reticulum (ER) in eukaryotes.

7 across all Cyanobacteria and photosynthetic eukaryotes.

8 tal timing, organogenesis and development in eukaryotes.

9 f chromatin structure and gene regulation in eukaryotes.

10 for proteins formerly considered specific to eukaryotes.

11 of bidirectional replication in archaea and eukaryotes.

12 erning RNA lifetimes in both prokaryotes and eukaryotes.

13 ion in natural and artificial populations of eukaryotes.

14 ed by heterotrimeric G-proteins exist in all eukaryotes.

15 ar DNAs (eccDNAs) have been reported in most eukaryotes.

16 ) regulate diverse cellular processes in all eukaryotes.

17 hylotypes as well as between fungi and other eukaryotes.

18 at the chromatin level are widespread among eukaryotes.

19 r ion concentrations in both prokaryotes and eukaryotes.

20 e a synthesis to the CcO assembly process in eukaryotes.

21 e played a profound role in the evolution of eukaryotes.

22 w unique PNG mechanisms arose and evolved in eukaryotes.

23 arrangement for metabolic pathways in other eukaryotes.

24 rdering cell space in bacteria, archaea, and eukaryotes.

25 uding H2AZ and H2AX that are present in most eukaryotes.

26 inhibition is conserved between archaea and eukaryotes.

27 taining regulatory proteins found in complex eukaryotes.

28 on of RNA polymerase II transcription in all eukaryotes.

29 Epigenetic states are stably propagated in eukaryotes.

30 e, bacteria, archaea, and simple and complex eukaryotes.

31 is crucial during the development of diverse eukaryotes.

32 -free analysis of mtDNA transcription in all eukaryotes.

33 E3 ubiquitin ligases and the kinetochore in eukaryotes.

34 ne of the key features of gene regulation in eukaryotes.

35 ing acidity of intracellular compartments in eukaryotes.

36 choline phosphotransferase that is common in eukaryotes.

37 the first independent I9 inhibitor in higher eukaryotes.

38 gulate a wide array of cellular functions in eukaryotes.

39 ies of interlocking feedback architecture in eukaryotes.

40 assessment of gene function in bacteria and eukaryotes.

41 ar this process has not been investigated in eukaryotes.

42 polymerases and replication in bacteria and eukaryotes.

43 ariety of important regulatory roles in many eukaryotes.

44 h ubiquitin chains controls cell fate in all eukaryotes.

45 which is conserved among a wide spectrum of eukaryotes.

46 tion into different cellular compartments in eukaryotes.

47 op GTPases and is conserved from bacteria to eukaryotes.

48 abeta-tubulin heterodimers essential for all eukaryotes.

49 ene-expression-associated epigenomic mark in eukaryotes.

50 , but is not as frequent or diverse in other eukaryotes.

51 a and chloroplast division in photosynthetic eukaryotes.

52 olutionary questions on uncultured microbial eukaryotes.

53 ell growth and organismal homeostasis across eukaryotes.

54 otic transition on the organellar genomes of eukaryotes.

55 ubunits, regulate key signaling processes in eukaryotes.

56 -randomly organized in the nucleus of higher eukaryotes.

57 pathway for phosphatidylcholine synthesis in eukaryotes.

58 riptional regulators to RNA polymerase II in eukaryotes.

59 d solution to the problem of size control in eukaryotes.

60 esent in phage T7 and in mitochondria of all eukaryotes.

61 a master regulator of energy homeostasis in eukaryotes.

62 vidence for the ancient chimeric ancestry of eukaryotes.

63 s in multiple processes that occur in higher eukaryotes.

64 eome expansion and gene regulation in higher eukaryotes.

65 one of the most common RNA modifications in eukaryotes.

66 e-tuning and broadening of Hsp70 function in eukaryotes.

67 +) signaling is essential for development in eukaryotes.

68 -subunit B-family replicative polymerases of eukaryotes.

69 he fundamental pathways of ATP generation in eukaryotes.

70 istribution of crossovers in a wide range of eukaryotes.

71 ed for linear chromosome maintenance in most eukaryotes.

72 ved mechanisms of signal transduction across eukaryotes.

73 he majority of cases of pre-mRNA splicing in eukaryotes.

74 conserved post-translational modification in eukaryotes.

75 orate network inference and underperforms in eukaryotes.

76 as well as the spliceosomal protein Prp8 in eukaryotes.

77 em regulates essential cellular processes in eukaryotes.

78 s a potential threat to genomic stability in eukaryotes.

79 sensor and master regulator of metabolism in eukaryotes.

80 cepted that tubulin and actin were unique to eukaryotes.

81 ifferent from viruses infecting bacteria and eukaryotes.

82 nds on a contractile actomyosin ring in many eukaryotes [1-3].

83 space (>100 mM) and within the cytoplasm in eukaryotes (10 approximately 20 mM).

84 etermining regions known thus far in complex eukaryotes ( 100 kbp) with comprehensive tests for sexua

85 1) a square-wave electroporator designed for eukaryotes, (2) a novel microfluidic transfection system

86 In eukaryotes, a dynamic ribonucleic protein machine known

87 overy of tRNA cytosine-to-uridine editing in eukaryotes, a reaction that has not been recapitulated i

88 defense systems that protect prokaryotes and eukaryotes against the proliferation of infectious or in

89 Among photosynthetic eukaryotes, all three subunits chlL, chlN, and chlB are

90 initiation generally occurs at AUG codons in eukaryotes, although it has been shown that non-AUG or n

91 rols with modified side chains are unique to eukaryotes, although simpler sterols can also be synthes

92 vated Mimiviridae, and three associated with eukaryotes among the Dinophyceae, Rhizaria, Alveolata, a

93 As in eukaryotes, an opposing activity counteracts the modific

94 In all eukaryotes analyzed to date, serine palmitoyltransferase

95 In eukaryotes and archaea, cis-PT is the first enzyme commi

96 pressed ubiquitously in both prokaryotes and eukaryotes and are subdivided into 25 thioesterase famil

97 e plasticity (DAMP) at multiple loci in both eukaryotes and bacteria, with up to 23-fold lower mutati

98 ions predates the evolutionary split between eukaryotes and bacteria.

99 most diverse group of membrane receptors in eukaryotes and detect a wide array of cues in the human

100 ma antigen (MAGE) genes are conserved in all eukaryotes and encode for proteins sharing a common MAGE

101 ungi, far exceeding levels observed in other eukaryotes and more derived fungi.

102 of the most common protein modifications in eukaryotes and occurs co-translationally when the N-term

103 y mitochondrial DNA is an ongoing process in eukaryotes and plays an important role in genomic variab

104 Eukaryotes and prokaryotes last shared a common ancestor

105 ine proteases are found ubiquitously in both eukaryotes and prokaryotes, and they comprise the larges

106 They are present in diverse cells of eukaryotes and prokaryotes.

107 cally interconnected glycerophospholipids in eukaryotes and prokaryotes.

108 in ATP-dependent protein remodeling in both eukaryotes and prokaryotes.

109 species (mutualisms) shaped the evolution of eukaryotes and remain critical to the survival of specie

110 ic membrane protein complex denoted Sec61 in eukaryotes and SecYEG in bacteria.

111 l role in the transition from prokaryotes to eukaryotes and the subsequent explosive diversification

112 Numerous Gram-negative pathogens infect eukaryotes and use the type III secretion system (T3SS)

113 T7SS substrates, including interactions with eukaryotes and with other bacteria.

114 double-strand break repair pathway in higher eukaryotes) and is stimulated by XLF.

115 ulated by posttranslational modifications in eukaryotes, and both cases are coordinated by the proces

116 linear DNA molecules is unprecedented among eukaryotes, and highlights unexpected variation in plast

117 ) is the most abundant RNA-binding domain in eukaryotes, and it plays versatile roles in RNA metaboli

118 ssential for cell division and growth in all eukaryotes, and knowledge of their sequence and structur

119 TPases) drive organelle acidification in all eukaryotes, and membrane-bound a-subunit isoforms of the

120 temperature in modulating SpCas9 activity in eukaryotes, and provides a simple method to increase on-

121 ns are widely distributed in prokaryotes and eukaryotes, and recognized as small-molecule binding pro

122 stability that are conserved in perhaps all eukaryotes, and suggest that Clk, cyc, and cry expressio

123 eres possess a ssDNA overhang like the other eukaryotes, and that the terminin complex is architectur

124 the ages of crown groups for photosynthetic eukaryotes, and the independent incorporation of a cyano

125 disordered proteins (IDPs) are ubiquitous in eukaryotes, and they are often associated with diseases

126 Endosymbioses between two eukaryotes are also known; cyanobacterium-derived plasti

127 Argonaute (Ago) proteins in eukaryotes are known as key players in post-transcriptio

128 sis, numerous lines of evidence suggest that eukaryotes are no more bioenergetically efficient than p

129 ein phosphatase identified in photosynthetic eukaryotes as well as a protein phosphatase target of th

130 d plastids have spread horizontally when one eukaryote assimilated another.

131 te genome chromosomes of all prokaryotes and eukaryotes available at NCBI, we observed that physico-c

132 Plants, lower eukaryotes, bacteria, and archaebacteria synthesise L-hi

133 etabolism to cell biology and development in eukaryotes, bacterial regulation of eukaryotic mating wa

134 he origin and evolution of photosynthesis in eukaryotes, bacterial-algal interactions, control of mas

135 , an essential replication protein unique to eukaryotes, binds CMG and greatly stimulates its helicas

136 They are ubiquitously found in eukaryotes but no prokaryotic homolog has been character

137 cient rocks not only signals the presence of eukaryotes, but also aerobic metabolic processes.

138 ) A) of mRNA is an essential process in most eukaryotes, but its role and the status of factors accom

139 several components are widely distributed in eukaryotes, but key components are absent in some lineag

140 peat (WDR) proteins is one of the largest in eukaryotes, but little is known about their function in

141 Ub is known to be highly conserved among eukaryotes, but surprisingly, ISG15 is highly divergent

142 regulates essential genome functions across eukaryotes, but the fundamental question of whether nucl

143 ulates mtHsp70's chaperone activity in lower eukaryotes, but the mammalian orthologs are unknown.

144 Vps13 proteins are conserved in eukaryotes, but their molecular function remains unknown

145 l steps of protein-coding gene expression in eukaryotes can be studied in isolation in vitro, it has

146 that established the chloroplast lineage in eukaryotes can be traced back to a single event, in whic

147 s a common posttranslational modification in eukaryotes catalyzed by protein arginine methyltransfera

148 In eukaryotes, compartmentalization minimizes inevitable en

149 Genome duplication in eukaryotes created paralog pairs of ribosomal proteins (

150 s, proteomic profiling of cilia from diverse eukaryotes defines a conserved ciliary proteome, reveals

151 this relationship is conserved in the simple eukaryote Dictyostelium and exploit this organism to def

152 In eukaryotes, DNA replication initiates from multiple orig

153 somes, but current models suggest that other eukaryotes do not have a sliding ring.

154 Present day eukaryotes employ at least two main defence strategies t

155 acid 5-hydroxytryptophan in both E. coli and eukaryotes, enabling efficient site-specific incorporati

156 rs are important in models for the origin of eukaryotes, especially as major gaps in our knowledge of

157 To elucidate the nature of this eukaryote-eukaryote association, we sequenced the genome

158 coding capacity exceeding that of all other eukaryotes except the distantly related jakobids and Dip

159 anticipate such daily cycles, prokaryote and eukaryote free-living organisms evolved intrinsic clocks

160 DNA binding module, which is conserved among eukaryotes from yeast to humans.

161 A common feature of eukaryote genomes is large chromosomal regions where rec

162 modeling factors play essential roles during eukaryote growth and development.

163 provide insights into how a highly divergent eukaryote has re-wired protein N-glycosylation to provid

164 Moreover, lower eukaryotes have a single member of the ChaC family that

165 proteomic and ribosome profiling studies in eukaryotes have concurrently demonstrated the translatio

166 bacteria, archaea, viruses and single-celled eukaryotes have crucial roles in the environment and in

167 diments is dominated by microalgae, which as eukaryotes have different anaerobic metabolic pathways t

168 otein products under environmental stresses, eukaryotes have evolved a set of signaling mechanisms kn

169 us diseases pose a threat to host integrity, eukaryotes have evolved mechanisms to eliminate pathogen

170 DT in the late 1960s, most studies on TLS in eukaryotes have focused on DNA lesions resulting from ul

171 a specific SMC protein dimer (heterodimer in eukaryotes) held together via their hinge domains.

172 Centromeric proteins are conserved among eukaryotes; however, centromeric DNA sequences are highl

173 ol for high throughput analysis of microbial eukaryotes in environmental samples.

174 ent compared to other Plasmodium species and eukaryotes in general - nearly 80% in coding regions and

175 Asgard archaea affiliate with eukaryotes in phylogenomic analyses, and their genomes a

176 fers substantially in bacteria, archaea, and eukaryotes in terms of the requirements for accessory fa

177 otein-only RNase P (PRORP), is widespread in eukaryotes in which it can provide organellar or nuclear

178 lipophilic molecule in both prokaryotes and eukaryotes in which it primarily acts as an electron car

179 mechanistic insights into the HSR in higher eukaryotes, in particular in mammals, are limited.

180 These kinases are conserved in many eukaryotes including humans, suggesting that similar con

181 II nucleases in response to virus in diverse eukaryotes including plants, arthropods, fish, and mamma

182 Mitochondrial fusion occurs in many eukaryotes, including animals, plants, and fungi.

183 amma radiation across archaea, bacteria, and eukaryotes, including fungi and human cells.

184 o mediating the action of hormones in higher eukaryotes, including human.

185 TPases involved in key cellular processes in eukaryotes, including vesicle trafficking and organelle

186 le formation, but experiments in unicellular eukaryotes indicate that delta-tubulin and epsilon-tubul

187 In eukaryotes, initiation factor 2 (eIF2) plays an importan

188 Bacteria and eukaryotes interact in many ways-from the microbiome tha

189 We show that in eukaryotes, inverse strand exchange between homologous d

190 Endosymbiosis of bacteria by eukaryotes is a defining feature of cellular evolution.

191 biogenesis of iron-sulfur (Fe/S) proteins in eukaryotes is a multistage, multicompartment process tha

192 Viral replication in eukaryotes is a process inherently organized in both spa

193 al organization of phospholipid synthesis in eukaryotes is critical for cellular homeostasis.

194 sensing via the Cys-Arg/N-end rule in higher eukaryotes is linked through a single mechanism to nitri

195 that regulation of O-mannosylation in higher eukaryotes is more complex than envisioned, and the disc

196 nitiation, and the DNA primase-polymerase in eukaryotes is pol alpha.

197 uired for survival of all cells, and in most eukaryotes, is produced through a series of eight enzyma

198 In eukaryotes, it is cleared via a mitochondrial sulfide ox

199 has proven to be a powerful genetic tool in eukaryotes, its application in Bacteria has been limited

200 ic foraminifera eDNA, a group of unicellular eukaryotes known to be good bioindicators, as features t

201 ns has lost glycolysis and, uniquely amongst eukaryotes, lacks any obvious intrinsic means of generat

202 have been restricted to sexually reproducing eukaryotes, leaving a major gap in our understanding of

203 gene expression data, especially for complex eukaryotes like human.

204 Explosive diversification is widespread in eukaryotes, making it difficult to resolve phylogenetic

205 All eukaryotes may have such enzymes for processing noncodin

206 Eukaryotes metabolize OP via an ATP-dependent 5-oxoproli

207 gh these canonical structures predominate in eukaryotes, microtubules with divergent protofilament nu

208 In eukaryotes, most RNA molecules are exported into the cyt

209 During ribosome biogenesis in eukaryotes, nascent subunits are exported to the cytopla

210 n is a fundamental cellular process that, in eukaryotes, occurs in the lumen of both the Golgi appara

211 that the link topology is characteristic of eukaryotes only.

212 hinery is fundamentally conserved throughout eukaryotes, our findings will help advance the rapidly e

213 ng with ExoI in Escherichia coli, or Sae2 in eukaryotes, palindromic amplifications arise and propaga

214 nalyzed the transcriptome of the intron-rich eukaryote Paramecium tetraurelia.

215 evolved from autosomes many times across the eukaryote phylogeny.

216 Pico-sized eukaryotes play key roles in the functioning of marine e

217 conserved non-histone chromosomal protein in eukaryotes, plays important roles in the regulation of g

218 Many eukaryotes possess a CTD devoid of repeats, appropriatel

219 Although eukaryotes possess a number of redundancies for initiati

220 The well-studied eukaryotes possess a tandemly repeated 7-amino-acid sequ

221 In eukaryotes, precursor mRNA (pre-mRNA) splicing removes n

222 Although prevalent in eukaryotes, prions have not been identified in bacteria.

223 It was thought that only eukaryotes produce significant amounts of DMSP(7-9), but

224 In eukaryotes, protein kinase A (PKA) is a master regulator

225 sed viruses in prokaryotes, the emergence of eukaryotes provided the necessary compartmentalization a

226 es from cryptic promoters and is observed in eukaryotes ranging from yeast to mammals.

227 In eukaryotes, reactions responsible of the conversion of l

228 anscription by RNA polymerase II (RNAPII) in eukaryotes rely on the transcriptional regulatory elemen

229 nificance of differentially present genes in eukaryotes remains poorly understood.

230 of this modification both in bacteria and in eukaryotes remains to be fully determined.

231 er this mechanism functions in multicellular eukaryotes remains unclear.

232 Whether 5' NAD-RNA exists in eukaryotes remains unknown.

233 , Tetrahymena thermophila is among the first eukaryotes reported to contain 6mA modification.

234 The origin and cellular complexity of eukaryotes represent a major enigma in biology.

235 bility that appearance of this PTM in higher eukaryotes represents an evolutionary substitution for H

236 Cytokinesis in many eukaryotes requires an actomyosin-based contractile ring

237 Efficient protein synthesis in eukaryotes requires diphthamide modification of translat

238 The expression of intron-containing genes in eukaryotes requires generation of protein-coding messeng

239 nd other O-acylated proteins in bacteria and eukaryotes revealed specific patterns.

240 In eukaryotes, RNA polymerase II (pol II) transcribes all p

241 In eukaryotes, RNA silencing, mediated by small interfering

242 Like other eukaryotes, S. cerevisiae undergoes a dramatic reprogram

243 rium Bacillus subtilis and the single-celled eukaryote Saccharomyces cerevisiae.

244 d genes encoding metabolic activities in the eukaryote, Saccharomyces cerevisiae.

245 In eukaryotes, several "hub" proteins integrate signals fro

246 We infer that stem eukaryotes shared functionally modern sterol biosynthesi

247 As key regulators of gene expression in eukaryotes, small RNAs have been characterized in many s

248 e fucosylated antennae typical of many other eukaryotes; some of these fucose residues are capped wit

249 esting a previously unidentified role of the eukaryote-specific cofactor in substrate interaction.

250 We demonstrate that the eukaryote-specific RpL4 extension harbours overlapping b

251 We find the emergence of a eukaryote-specific signature for interclass complexation

252 Our results expand the known repertoire of 'eukaryote-specific' proteins in Archaea, indicating that

253 eroxidases are already present in mycetozoan eukaryotes such as Dictyostelium discoideum This social

254 possess several features that are typical of eukaryotes, such as cytosolic compartmentalization and e

255 NA(Ala) is conserved across all bacteria and eukaryotes, suggesting DTD's key cellular role as a glyc

256 In eukaryotes, sulfur is mobilized for incorporation into m

257 or predictor of Hi-C contact maps in several eukaryotes tested, including C. elegans and A. thaliana.

258 igenetic mark across a more diverse range of eukaryotes than previously realized.

259 respectively-in Saccharomyces cerevisiae, a eukaryote that lacks endogenous protein AMPylation.

260 asite Trypanosoma brucei, an early branching eukaryote that lacks transcriptional regulation and regu

261 nisms of dependency on plastid organelles in eukaryotes that have lost photosynthesis; it also sugges

262 e the most abundant protein-DNA complexes in eukaryotes that provide compaction of genomic DNA and ar

263 s) are 21-24-nucleotide RNAs present in many eukaryotes that regulate gene expression as part of the

264 new avenue to phosphoproteome regulation in eukaryotes that will be instrumental for the development

265 In eukaryotes, the basal transcription in interphase is orc

266 In eukaryotes, the Cdc45-MCM-GINS (CMG) helicase and the le

267 In eukaryotes, the conjugation of the ubiquitin-like protei

268 e largest family of cell surface proteins in eukaryotes, the G protein-coupled receptors (GPCRs).

269 ptional activators of heat shock response in eukaryotes, the heat shock factors (HSFs), have undergon

270 ough only a single MAGE gene exists in lower eukaryotes, the MAGE family rapidly expanded in eutheria

271 Within eukaryotes, the majority of HTs reported so far are tran

272 ways in different hosts.IMPORTANCE In higher eukaryotes, the majority of transcribed RNAs do not enco

273 In photosynthetic eukaryotes, the metabolite exchange between chloroplast

274 In higher eukaryotes, the microRNA biogenesis enzyme Dicer forms a

275 ways are evolutionarily conserved throughout eukaryotes, the msn2Deltamsn4Delta strain could therefor

276 In eukaryotes, the ribosome-bound quality control (RQC) com

277 In larger eukaryotes, the stress-induced transcriptional response

278 In eukaryotes, they are implicated in cell volume regulatio

279 biosynthesis pathway is highly conserved in eukaryotes, this finding, as we show in our separate rep

280 In eukaryotes, this motif coordinates the synchronous and s

281 t the poly(A)-tail also provides a basis for eukaryotes to effectively shut down mature mRNA transpor

282 In eukaryotes, transcriptionally inactive loci are enriched

283 n J-protein biology during the prokaryote-to-eukaryote transition allows for increased fine-tuning an

284 Most modern eukaryotes transmit mitochondrial genes uniparentally, o

285 In eukaryotes, ubiquitin is encoded both as a monomeric ubi

286 Eukaryotes utilize Ca(2+) as a universal second messenge

287 This finding sheds light on how eukaryotes utilize RNA to repair chromosome breaks.

288 ential to almost all biological processes in eukaryotes, was also found to play an important role in

289 By focusing on one migration mode in many eukaryotes, we identify a genetic marker of pseudopod fo

290 share characteristics with both bacteria and eukaryotes, we investigated whether and how archaeal cel

291 e also present in photosynthetic unicellular eukaryotes, where their physiological role and regulatio

292 ore copper in the cytosol of prokaryotes and eukaryotes, where this reactivity is also key to toxicit

293 accordion" model of genome size evolution in eukaryotes whereby DNA loss counteracting TE expansion i

294 ng (AS) is a crucial regulatory mechanism in eukaryotes, which acts by greatly increasing transcripto

295 the three routes leading to PE synthesis in eukaryotes, while PS synthesis has not been studied expe

296 fect bacterial or archaeal hosts (viruses of eukaryotes will be added at a future date).

297 nosome Trypanosoma brucei is a single-celled eukaryote with a single cilium/flagellum.

298 We show here that, contrarily to other eukaryotes with symmetric division, budding yeast keeps

299 are responsible for domain structure in all eukaryotes, with CTCF playing an important role in domai

300 rives faithful chromosome segregation in all eukaryotes, yet the underlying machinery is diverse acro