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6 ated phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) b
7 nt with salubrinal, a selective inhibitor of eukaryotic translation initiation factor 2 (eIF2alpha) d
8 RI, PKR, and PERK specifically phosphorylate eukaryotic translation initiation factor 2 (eIF2alpha) o
9 stances, ph-PKR targets the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) p
10 H2S transiently increases phosphorylation of eukaryotic translation initiation factor 2 (eIF2alpha) r
11 g kinases phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) t
13 ), which phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha),
14 duce phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 (eIF2alpha),
15 d by phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha),
16 ISR) by phosphorylating the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha).
17 formation of phosphorylated alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha-P)
18 Heme-regulated inhibitor kinase (HRI), a eukaryotic translation initiation factor 2 alpha (eIF2al
19 displaying PI-induced phosphorylation of the eukaryotic translation initiation factor 2 alpha (eIF2al
20 of protein kinase R (PKR) and its substrate eukaryotic translation initiation factor 2 alpha (eIF2al
21 we found that, translational control by the eukaryotic translation initiation factor 2 alpha (eIF2al
22 e of PAH, whereas biallelic mutations in the eukaryotic translation initiation factor 2 alpha kinase
23 nd sustained activation (phosphorylation) of eukaryotic translation initiation factor 2 alpha kinase
24 ature, including complement protein C1qB and eukaryotic translation initiation factor 2 alpha kinase
25 These results suggest that UV light-induced eukaryotic translation initiation factor 2 alpha-subunit
26 hich the phosphorylation site, Ser-51 in the eukaryotic translation initiation factor 2 alpha-subunit
27 ism, we demonstrated that phosphorylation of eukaryotic translation initiation factor 2 at Ser-51 on
28 r of cellular complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit alpha
29 ng pathways result in phosphorylation of the eukaryotic translation initiation factor 2 subunit alpha
31 guanine nucleotide exchange factor (GEF) for eukaryotic translation initiation factor 2, which stimul
33 orylates its substrate, the alpha-subunit of eukaryotic translation initiation factor-2 (eIF2alpha) l
35 and phosphorylate cellular targets, such as eukaryotic translation initiation factor 2alpha (eIF-2al
36 hosphorylate the regulatory serine 51 of the eukaryotic translation initiation factor 2alpha (eIF2alp
37 The integrated stress response mediated by eukaryotic translation initiation factor 2alpha (eIF2alp
39 at ECM detachment activates a canonical PERK-eukaryotic translation initiation factor 2alpha (eIF2alp
41 he genus Ranavirus encode a homologue of the eukaryotic translation initiation factor 2alpha (eIF2alp
42 inase knockout (PERK-KO) or phosphodeficient eukaryotic translation initiation factor 2alpha (eIF2alp
44 additionally induces the phosphorylation of eukaryotic translation initiation factor 2alpha (eIF2alp
45 iral infection by actively dephosphorylating eukaryotic translation initiation factor 2alpha (eIF2alp
46 ein kinase/endoribonuclease, and ER-resident eukaryotic translation initiation factor 2alpha (eIF2alp
47 to activation of PKR-like ER kinase (PERK), eukaryotic translation initiation factor 2alpha (eIF2alp
48 nases, including GCN2 and PKR, phosphorylate eukaryotic translation initiation factor 2alpha (eIF2alp
49 nhanced protein levels in the heme-regulated eukaryotic translation initiation factor 2alpha (eIF2alp
50 NA of CReP/Ppp1r15b, a regulatory subunit of eukaryotic translation initiation factor 2alpha (eIF2alp
51 smic reticulum stress and phosphorylation of eukaryotic translation initiation factor 2alpha (eIF2alp
52 a the 5' UTRalpha and phosphorylation of the eukaryotic translation initiation factor 2alpha (eIF2alp
53 served markedly increased phosphorylation of eukaryotic translation initiation factor 2alpha (p-eIF2a
54 e ER kinase-dependent phosphorylation of the eukaryotic translation initiation factor 2alpha and enha
55 stress-inducible kinase that phosphorylates eukaryotic translation initiation factor 2alpha and spec
56 pore complex interacting protein (NPIP) and eukaryotic translation initiation factor 2alpha kinase (
57 ously showed that the PKR-like, ER-localized eukaryotic translation initiation factor 2alpha kinase b
59 ing by GCN1.GCN20 and a stronger decrease in eukaryotic translation initiation factor 2alpha phosphor
60 sis, through activating pancreatic ER kinase/eukaryotic translation initiation factor 2alpha signalin
61 asGAP SH3-binding protein and phosphorylated eukaryotic translation initiation factor 2alpha unchange
62 ylation of protein kinase-like ER kinase and eukaryotic translation initiation factor 2alpha, and the
63 logous protein as well as phosphorylation of eukaryotic translation initiation factor 2alpha, indicat
64 g arsenite stress-induced phosphorylation of eukaryotic translation initiation factor 2alpha, inhibit
65 increased the levels of Bip, phosphorylated eukaryotic translation initiation factor 2alpha, inosito
66 four protein kinases known to phosphorylate eukaryotic translation initiation factor 2alpha, only th
67 ss-induced RNAs; tiRNAs) induces the phospho-eukaryotic translation initiation factor 2alpha-independ
69 EIF2AK3), the latter of which phosphorylates eukaryotic translation initiation factor-2alpha (eIF2alp
70 visiae translation initiation factor complex eukaryotic translation initiation factor 2B (eIF2B) and
74 d by mutations in genes encoding subunits of eukaryotic translation initiation factor 2B (eIF2B).
75 pomyelinating disease caused by mutations in eukaryotic translation initiation factor 2B (eIF2B).
76 nous GSK-3beta, inhibited phosphorylation of eukaryotic translation initiation factor 2B epsilon, and
77 uMV resistance 03 (retr03), an allele of the eukaryotic translation initiation factor 2B-beta (eIF2Bb
79 the antihypertrophic effect of GSK-3beta is eukaryotic translation initiation factor 2Bepsilon (eIF2
81 er of the initiation pathway, the 13-subunit eukaryotic translation initiation factor 3 (eIF3) contro
82 CTD) of the a/Tif32 subunit of budding yeast eukaryotic translation initiation factor 3 (eIF3) intera
87 e can be isolated from cells in complex with eukaryotic translation initiation factor 3 and ribosomal
88 protein metabolism were upregulated, such as eukaryotic translation initiation factor 3 and ribosome
89 -beta3 translation, a process that involved eukaryotic translation initiation factor 3 subunit b as
93 OP9 signalosome, the proteasome lid, and the eukaryotic translation initiation factor 3, are revealin
94 report that the protein translation factor, eukaryotic translation initiation factor 3, subunit a (e
97 Complex assembly of the mRNA cap protein, eukaryotic translation initiation factor 4 (eIF4)E, with
98 is largely exerted at initiation through the eukaryotic translation initiation factor 4 F (eIF4F).
99 arboxypeptidase E (CPE) by inhibition of the eukaryotic translation initiation factor 4 gamma 1 trans
100 ro8 mutation is in the Eif4g3 gene, encoding eukaryotic translation initiation factor 4, gamma 3.
103 phila Dpp pathway is negatively regulated by eukaryotic translation initiation factor 4A (eIF4A), whi
104 ollagen alpha2(I) mRNAs, by interacting with eukaryotic translation initiation factor 4A (eIF4A).
105 of the Su(dpp) mutations as an allele of the eukaryotic translation initiation factor 4A (eIF4A).
106 ) 1B (alpha-, beta-, and gamma-subunits) and eukaryotic translation initiation factor 4A (three isofo
108 4 directly inhibits the helicase activity of eukaryotic translation initiation factor 4A, a component
111 , using antibodies to EJC components Y14 and eukaryotic translation initiation factor 4aIII (eIF4AIII
112 peptide library profiling, we identified the eukaryotic translation initiation factor 4B (eIF4B) as a
115 Here, we found that the protein level of eukaryotic translation initiation factor 4B (eIF4B), an
116 found that ORF45 induced phosphorylation of eukaryotic translation initiation factor 4B (eIF4B), inc
117 of IFNs on the phosphorylation/activation of eukaryotic translation initiation factor 4B (eIF4B).
119 tion initiation factor 4E-binding protein 1/ eukaryotic translation initiation factor 4E (4EBP1/eIF4E
120 f acute myeloid leukemia (AML) by regulating eukaryotic translation initiation factor 4E (eIF4E) acti
121 ERK activation stimulated phosphorylation of eukaryotic translation initiation factor 4E (eIF4E) and
122 s been found to be based on mutations in the eukaryotic translation initiation factor 4E (eIF4E) and
123 of translation engage mRNA that is bound by eukaryotic translation initiation factor 4E (eIF4E) at t
124 se interacting serine/threonine kinase (MNK)-eukaryotic translation initiation factor 4E (eIF4E) axis
126 EITC caused an increase in expression of the eukaryotic translation initiation factor 4E (eIF4E) bind
128 hrough simultaneous activation of mTORC1 and eukaryotic translation initiation factor 4E (eIF4E) by N
132 Here we show that a functional reduction of eukaryotic translation initiation factor 4E (eIF4E) in D
133 ow that genetically increasing the levels of eukaryotic translation initiation factor 4E (eIF4E) in m
141 clear retention of PCBP1, recruitment to the eukaryotic translation initiation factor 4E (eIF4E) prom
142 hibitor of kappaB alpha (IkappaB-alpha) S32, eukaryotic translation initiation factor 4E (eIF4E) S209
143 down-regulated by JNK2alpha2APF, among which eukaryotic translation initiation factor 4E (eIF4E) show
145 tion-dissociation of the cap-binding protein eukaryotic translation initiation factor 4E (eIF4E) with
150 nclude ribosomal protein S6 kinase 1 (S6K1), eukaryotic translation initiation factor 4E (eIF4E), and
152 rs often overexpress the cap binding protein eukaryotic translation initiation factor 4E (eIF4E), lea
153 K signals to Mnk1 lead to phosphorylation of eukaryotic translation initiation factor 4E (eIF4E), whi
154 mRNA translation by promoting sumoylation of eukaryotic translation initiation factor 4E (eIF4E), whi
155 The rate-limiting factor for translation is eukaryotic translation initiation factor 4E (eIF4E), whi
157 ing means to target a specific oncogene, the eukaryotic translation initiation factor 4E (eIF4E), wit
158 rgistically inhibited phosphorylation of the eukaryotic translation initiation factor 4E (eIF4E)-bind
159 bserved that Eap1p, which is a member of the eukaryotic translation initiation factor 4E (eIF4E)-bind
160 tioning in mice, we investigated the role of eukaryotic translation initiation factor 4E (eIF4E)-eIF4
161 K and AKT signaling are required to activate eukaryotic translation initiation factor 4E (eIF4E)-init
163 A translation is dependent on mTORC1 and the eukaryotic translation initiation factor 4E (eIF4E).
164 erminal domain, which displays similarity to eukaryotic translation initiation factor 4E (eIF4E).
165 ition or blockade of its downstream effector eukaryotic translation initiation factor 4E activity equ
166 ransition machinery, decreases expression of eukaryotic translation initiation factor 4E and cyclin D
167 in HuR and the posttranscriptional regulator eukaryotic translation initiation factor 4E as two possi
168 ts demonstrate the importance of the p38-MNK-eukaryotic translation initiation factor 4E axis in TNF
169 apamycin (mTOR)-dependent phosphorylation of eukaryotic translation initiation factor 4E binding prot
170 ibosomal protein S6, S6 kinase 1 (S6K1), and eukaryotic translation initiation factor 4E binding prot
172 t, mammalian target of Rapamycin (mTOR), and eukaryotic translation initiation factor 4E binding prot
174 reased sensitivity to dominant inhibition of eukaryotic translation initiation factor 4E function.
175 and also reduce the level of phosphorylated eukaryotic translation initiation factor 4E in the tumor
176 s HuR) regulates the alternative splicing of eukaryotic translation initiation factor 4E nuclear impo
178 s of Akt, mammalian target of rapamycin, and eukaryotic translation initiation factor 4E phosphorylat
179 mport factor 1 (Eif4enif1), which encodes an eukaryotic translation initiation factor 4E transporter
180 ammalian target of rapamycin, phosphorylated eukaryotic translation initiation factor 4E, phosphoryla
181 p38 MAPK, MAPK-interacting kinase (MNK), and eukaryotic translation initiation factor 4E, which is a
182 hosphorylates and inactivates members of the eukaryotic translation initiation factor 4E-binding (eIF
183 rough an RNA-RNA interaction and an adjacent eukaryotic translation initiation factor 4E-binding 3'CI
184 kissing-loop T-shaped structure (kl-TSS) and eukaryotic translation initiation factor 4E-binding Pani
185 omplex 1, ribosomal protein S6 kinase 1, and eukaryotic translation initiation factor 4E-binding prot
186 ulation of the translation repressor, 4E-BP (eukaryotic translation initiation factor 4E-binding prot
187 tion of mammalian target of rapamycin (mTOR)/eukaryotic translation initiation factor 4E-binding prot
188 ncoding cell-cycle regulators via the mTORC1/eukaryotic translation initiation factor 4E-binding prot
189 pamycin (mTOR) signaling pathway to preserve eukaryotic translation initiation factor 4E-binding prot
190 ase (Chk) 1 serine 345 (S345), Chk 2 S33/35, eukaryotic translation initiation factor 4E-binding prot
191 anslation at a different level by inhibiting eukaryotic translation initiation factor 4E-binding prot
192 mitochondrial structure, and accumulation of eukaryotic translation initiation factor 4E-binding prot
193 Ser 79, tuberous sclerosis 2 at Thr 1462 and eukaryotic translation initiation factor 4E-binding prot
194 a constitutively active alternate substrate, eukaryotic translation initiation factor 4E-binding prot
195 tion of the 40S ribosomal protein S6 and the eukaryotic translation initiation factor 4E-binding prot
196 ammalian target of rapamycin (mTOR)-directed eukaryotic translation initiation factor 4E-binding prot
197 ribosomal protein S6 kinases (S6Ks) and the eukaryotic translation initiation factor 4E-binding prot
199 ing studies revealed hyperphosphorylation of eukaryotic translation initiation factor 4E-binding prot
200 properties: first, it preferentially targets eukaryotic translation initiation factor 4E-binding prot
202 ating p70S6K/ribosomal protein S6 (RPS6) and eukaryotic translation initiation factor 4E-binding prot
206 in CD4 T cells through the activation of the eukaryotic translation initiation factor 4E/MAPK-interac
207 regulators, including p70-S6 kinase and the eukaryotic translation initiation factor, 4E binding pro
210 mes, poxviruses must commandeer the critical eukaryotic translation initiation factor 4F (eIF4F) to r
212 n factor 4G (eIF4G), the scaffold subunit of eukaryotic translation initiation factor 4F (eIF4F), pre
213 tional control by constitutive activation of eukaryotic translation initiation factor 4F (eIF4F), the
214 ese events are required for formation of the eukaryotic translation initiation factor 4F complex (eIF
215 an Arg- and Ser-rich segment (RS1 domain) of eukaryotic translation initiation factor 4G (eIF4G) and
216 nslation initiation factors, including human eukaryotic translation initiation factor 4G (eIF4G) and
221 n translation initiation by interaction with eukaryotic translation initiation factor 4G (eIF4G), we
222 ed with both protein synthesis and levels of eukaryotic (translation) initiation factor 4G1 (eIF4G1).
225 This is accompanied by the cleavage of the eukaryotic translation initiation factor 4GI (eIF4GI).
229 denosylmethionine decarboxylase 1 (AMD1) and eukaryotic translation initiation factor 5A (eIF5A), two
231 e in the biosynthesis of hypusine containing eukaryotic translation initiation factor 5A (eIF5A), whi
232 silon-(4-amino-2-hydroxybutyl)lysine) in the eukaryotic translation initiation factor 5A (eIF5A).
233 thione and for deoxyhypusine modification of eukaryotic translation initiation factor 5A (eIF5A).
237 of this Gly in the Switch II element of the eukaryotic translation initiation factor 5B (eIF5B) from
238 Our data reveal a transient increase of eukaryotic translation initiation factor 5B (eIF5B), the
239 bunit joining is controlled by the G-protein eukaryotic translation initiation factor 5B (eIF5B).
240 Mutations that impair GTP hydrolysis by eukaryotic translation initiation factor 5B/initiation f
241 RKR-like endoplasmic reticulum kinase (PERK)-eukaryotic translation initiation factor alpha (eIF2alph
242 on mutant induced protein kinase R (PKR) and eukaryotic translation initiation factor alpha (eIF2alph
243 i, global translation was fully restored and eukaryotic translation initiation factor alpha was depho
244 culum stress pathway proteins phosphorylated eukaryotic translation initiation factor alpha, phosphor
245 ) and its downstream targets, phosphorylated eukaryotic translation initiation factor and p70 S6 kina
246 tein kinase R (PKR) and the alpha subunit of eukaryotic translation initiation factor are not phospho
250 numerous functions of individual subunits of eukaryotic translation initiation factor (eIF) 3, little
253 H(2)O(2) also induced phosphorylation of eukaryotic translation initiation factor (eIF) 4E and eI
254 the 40S ribosomal protein S6 (rpS6) and the eukaryotic translation initiation factor (eIF) 4E-bindin
256 These pathways convergently signal to the eukaryotic translation initiation factor (eIF) 4F comple
262 site (IRES) with 40S ribosomal subunits and eukaryotic translation initiation factor (eIF)3 enable 4
263 argets both cap-binding complex (Cbc)1p- and eukaryotic translation initiation factor (eIF)4E-bound m
265 GCN2 phosphorylates the alpha subunit of the eukaryotic translation initiation factor eIF2, leading t
267 -stimulated gene product, phosphorylates the eukaryotic translation initiation factor eIF2alpha and c
268 n interferon-induced kinase that targets the eukaryotic translation initiation factor eIF2alpha.
269 -PP1 phosphatase activity, dephosphorylating eukaryotic translation initiation factor (eIF2alpha), an
270 ic labeling, we show that the mRNAs encoding eukaryotic translation initiation factors eIF2B2 and eIF
271 by regulating the local protein synthesis of eukaryotic translation initiation factors eIF2B2 and eIF
274 ic PAS usage regulates the expression of the eukaryotic translation initiation factor EIF4A1, the tum
284 o improve outcomes and include targeting the eukaryotic translation initiation factor (eIF4E) with it
285 quire resistance to asTORi by downregulating eukaryotic translation initiation factor (eIF4E)-binding
287 ce gene, sbm1, in pea we have identified the eukaryotic translation initiation factor, eIF4E, as a su
288 found to be based on mutations in the plant eukaryotic translation initiation factors, eIF4E and eIF
289 in was associated with the 4F subunit of the eukaryotic translation initiation factor (eIF4F) complex
291 ovel approach to investigate the role of the eukaryotic translation initiation factor eIF5A in human
293 droxylase (DOHH) catalyzes the activation of eukaryotic translation initiation factor (eIF5A), a prot
296 en VPg of turnip mosaic virus and wheat germ eukaryotic translation initiation factors eIFiso4E and e
297 aliana knockout lines for the plant-specific eukaryotic translation initiation factors eIFiso4G1 (i4g
299 now present a novel study of rate control by eukaryotic translation initiation factors (eIFs) using y
300 unctions as an essential subunit of the eIF3 eukaryotic translation initiation factor in animals, yea
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