ライフサイエンスコーパス: evasion

1 vement of complex viral mechanisms of immune evasion.

2 their likely primary role is enabling immune evasion.

3 static disease, which is dependent on immune evasion.

4 ligands to interfere with cancer cell immune evasion.

5 eractions contribute to host adaptive immune evasion.

6 sential role in viral replication and immune evasion.

7 by M. tuberculosis may contribute to immune evasion.

8 and hypothesise new modes of pathogen immune evasion.

9 hlighting a novel strategy for innate immune evasion.

10 mmune inhibitory receptors to achieve immune evasion.

11 ional inactivation of CREBBP promotes immune evasion.

12 tors of host defense and mediators of immune evasion.

13 abolic target and mechanism of cancer immune evasion.

14 nvironment to promote oncogenesis and immune evasion.

15 site's genome and plays a key role in immune evasion.

16 al segment of apoptosis leading to apoptosis evasion.

17 provided a direct mechanism of tumor immune evasion.

18 eveloping novel targets against tumor immune evasion.

19 presents a bacterial strategy for CD4 T cell evasion.

20 y adaptable to sequence diversity and immune evasion.

21 previously unknown viral strategy of immune evasion.

22 f bacterial metabolism in host innate immune evasion.

23 lity of peptides for presentation and immune evasion.

24 ssential step for tissue invasion and immune evasion.

25 ly downregulated in tumors, resulting in CTL evasion.

26 onary dynamics and sites of selective immune evasion.

27 yte antigen (HLA) loss may facilitate immune evasion.

28 tigens that are unmasked during tumor immune evasion.

29 ing RCA disease-related mutations and immune evasion.

30 enitalium infection, persistence, and immune evasion.

31 own to play important roles in tumour immune evasion.

32 ion, including amino acid changes and immune evasion.

33 tween them in polymerase function and immune evasion.

34 tical effectors involved in bacterial immune evasion.

35 s the fate of ingested DNA in DCs for immune evasion.

36 induce PD-1 signaling and associated immune evasion.

37 umor cell apoptosis or decrease tumor immune evasion.

38 tion in HCCs, which contributes to treatment evasion.

39 sed for multiple functions, including immune evasion.

40 receptor usage and thereby to lead to immune evasion.

41 roviding a mechanism that may promote immune evasion.

42 domains that partially contributed to immune evasion.

43 Predator evasion, a behavior that enhances fitness, may depend up

44 To improve the Nab evasion ability of the haploid virus, we produced the tr

45 drupedal rodents, likely increasing predator evasion ability.

46 behavior that varies inversely with predator evasion ability.

47 ave the potential to exploit pathogen immune-evasion adaptations, a capability that might endow these

48 . aureus virulence factor involved in immune evasion and biofilm formation.

49 t functions including DNA competence, immune evasion and biofilm formation.

50 PDAC), where it coordinately mediates immune evasion and drug resistance.

51 l data from the year 2003 of corruption, tax evasion and fraudulent politics.

52 diated immunity, in part due to viral immune evasion and immunodeficiency resulting from CD4(+) T-cel

53 fected lungs, opsonization and phagocytosis, evasion and inhibition of neutrophil defense mechanisms,

54 echanisms of CMV entry, spread, and antibody evasion and may assist in determining which antibodies m

55 echanisms of CMV entry, spread, and antibody evasion and may have important implications for the deve

56 mouse models of NSCLC reverses tumor immune evasion and modulates T cell exhaustion state towards me

57 The resulting evasion and oxidation rates of 2.9 mmol m(-2) d(-1) and

58 Previous studies have quantified evasion and oxidation with point-scale measurements.

59 nase and deISGylase activities on viral host evasion and pathogenesis.

60 To overcome treatment evasion and reduce systemic effects, we developed CXCR4-

61 se data highlight the need to block multiple evasion and subversion mechanisms in tandem to kill P. a

62 P. aeruginosa has evolved numerous evasion and subversion mechanisms that work in concert t

63 l an essential role of CpsA in innate immune evasion and suggest that LCP proteins have functions bey

64 hanisms by which T. pallidum promotes immune evasion and survival, and demonstrate the exceptional po

65 wth arrest of Salmonella facilitating immune evasion and the establishment of a long-term niche, whil

66 we review the role of NLRC5 in cancer immune evasion and the future prospects for cancer research.

67 tro BIRC3 up-regulation results in apoptosis evasion and therapeutic resistance in GBM.

68 -hemolysin (CyaA) plays a key role in immune evasion and virulence of the whooping cough agent Bordet

69 to exploit these cells, facilitating immune evasion and virus dissemination.

70 lance makes C3 a target for microbial immune evasion and, if improperly engaged, a trigger point for

71 ry factor enhances viral infectivity, immune evasion, and AIDS progression.

72 it dormancy, resistance to apoptosis, immune evasion, and co-option of other tumor and stromal cells.

73 dysfunctional NET production, bacterial NET evasion, and decreased NET removal are associated with d

74 mechanisms for parasite development, immune evasion, and disease pathology.

75 ral basis of resistance to apoptosis, immune evasion, and loss of cell junctions seen in H. pylori-in

76 stasis, cancer stem cell maintenance, immune evasion, and resistance to chemotherapy and radiation th

77 role for JAK2/STAT1 in EGFR-mediated immune evasion, and therapies targeting this signaling axis may

78 icity, invasiveness, chemoresistance, immune evasion, and ultimately to poor prognosis of cancer pati

79 tumor malignancy, as hypoxia promotes immune evasion, angiogenesis, tumor cell survival, and metastat

80 or the pathogen Pseudomonas aeruginosa, this evasion appears to be triggered by excretion of the quor

81 Genomic instability and immune evasion are hallmarks of cancer.

82 suggest that bacterial metabolism and immune evasion are linked by virtue of this moonlighting protei

83 findings suggest a mechanism of viral immune evasion at the very earliest phase of infection.

84 ophysical changes are sufficient to initiate evasion away from an otherwise static tumor.

85 s a strategy that tumor cells use for immune evasion, but the underlying mechanisms are unclear.

86 Thus, ITAMi can be exploited for immune evasion by a pathogen and may represent a paradigm for I

87 , we establish a unique mode of inflammasome evasion by a pathogen, centered on a blood-feeding arthr

88 ides a clear molecular description of immune evasion by a persistent virus.

89 otein VII-SET interaction contributes to DDR evasion by adenovirus.

90 denticola FhbB protein contributes to immune evasion by binding factor H (FH).

91 ent to tumors is a major mechanism of immune evasion by cancer cells, our data highlight the importan

92 MO, KYNU) that play a pivotal role in immune evasion by certain other microbial pathogens by driving

93 a cell-surface molecule that promotes immune evasion by engaging signal-regulatory protein alpha (SIR

94 Immune evasion by HIV-1 during acute infection is critical for

95 Our studies revealed a strategy of immune evasion by MNV via the induction of a CD8(+) T cell prog

96 aying a potentially key role in the immunity evasion by mycoplasmas.

97 ork illustrates a striking example of immune evasion by persistent viruses.

98 ss the molecular mechanisms of innate immune evasion by select NNS viruses.

99 important role for indolepyruvate in immune evasion by T. brucei.

100 The molecular mechanisms of immune evasion by the parasite are poorly understood.

101 ential therapeutic target to overcome immune evasion by tumour cells.

102 Importantly, this mechanism of immune evasion can be circumvented with small-molecule CD4 mime

103 fore reliable bottom-up estimates of methane evasion can be determined at global scales.

104 This evasion can be due to point mutations (1) , large-scale

105 This viral immune evasion casts new light on the roles of CTLs and NK cell

106 MS is mainly attributable to a CD4(+) T-cell evasion caused by an impaired DNAX accessory molecule (D

107 Our results imply that to prevent host evasion, CTXPhi uses an infection strategy that targets

108 the IL-10 response as a mechanism of immune evasion during chronic systemic and biofilm models of in

109 PV E7 may contribute to virus-induced immune evasion during HPV persistence.

110 tein, ORF52, has an important role in immune evasion during KSHV primary infection, through inhibitio

111 2017) determine that norovirus innate immune evasion enables infection of intestinal epithelial cells

112 indicated additional HBs-independent immune evasion events.

113 V-encoded miR-BART16 as a novel viral immune-evasion factor that interferes with the type I IFN signa

114 system by upregulating expression of immune evasion factors in response to changes in temperature.

115 mRNAs control expression of bacterial immune evasion factors, including CssA, in the 5'-untranslated

116 s attributable to a large spectrum of immune evasion factors.

117 velocity k to produce a resulting map of CO2 evasion (FCO2 ).

118 tly inhibited endothelial cell migration and evasion from a 3D matrix.

119 evidence for both a novel strategy of virus evasion from cellular immunity and a novel role for a ce

120 half its mass and is a key component of HIV evasion from humoral immunity.

121 Furthermore, we show that rather than evasion from neutrophil-dependent bactericidal process,

122 orphyromonas gingivalis (Pg) capsule enables evasion from phagocytosis, invasion of keratinocytes, an

123 into the mechanisms of host and viral immune evasion from RIG-I, explaining the complexity of cap str

124 es to ensure either nutrient availability or evasion from the immune system.

125 lts indicate that, in addition to its immune evasion function, KSHV ORF52 is required for the optimal

126 now identify novel natural killer (NK) cell evasion functions for four members: US12, US14, US18 and

127 vitro Both viruses also encode innate immune evasion functions.

128 frame 50 (ORF50), transcripts for the immune evasion genes K3 and K5 were detected, with some downreg

129 Given that the virus expresses immune evasion genes or uses proteins with intrinsic properties

130 and heterogeneous mechanisms of tumor immune evasion has also expanded.

131 ion underpins antigenic variation and immune evasion in African trypanosomes.

132 iants (AR-Vs) provide a mechanism of therapy evasion in castrate-resistant prostate cancer (CRPC), ye

133 ter understanding of the processes of immune evasion in chronic infections and malignant tumors will

134 In order to study antibody recognition and evasion in detail, we analyzed a conformational epitope

135 r findings demonstrate a mechanism of immune evasion in IDH-MUT gliomas and suggest that specific inh

136 tumor-intrinsic mechanism underlying immune evasion in MIBC.

137 tor and its ligand (PD-L1) facilitate immune evasion in multiple myeloma (MM).

138 hermore, this variant displays robust immune evasion in nonhuman primate and human serum samples at d

139 as a unique and potent mediator of autophagy evasion in Plasmodium.

140 luding cell signaling, cell cycle and immune evasion, in their development.

141 in nude mice, exhibited signatures of immune evasion, increased stemness, increased calcium signaling

142 Immune evasion is a hallmark of cancer.

143 Among other potential explanations, immune evasion is considered to be a main driver of their succe

144 between host immune control and viral immune evasion is pivotal to viral pathogenesis, and we discuss

145 ion, suggesting that CpsY function in immune evasion is specific to the human host.

146 ate host immune responses, and innate immune evasion is thought to play a vital role in PRRSV pathoge

147 Inflammasome evasion likely was due to reduced expression of inflamma

148 e myeloid leukemia (AML), its role in immune evasion may be just as important.

149 deposition and intensifying droughts, NO gas evasion may become an increasingly important pathway for

150 These results suggest a novel immune evasion mechanism by which the HSV-1 LAT may contribute

151 pothesize that HBsAg is a major HBV-mediated evasion mechanism controlling endogenous antiviral respo

152 rferon receptor IFNAR1 chain as a new immune-evasion mechanism in colorectal cancers.

153 rvival, but phase variation can be an immune evasion mechanism, and thus, this modification may contr

154 y targeted MOV10 as a possible innate immune evasion mechanism.

155 proteolysis of galectin-3 is a novel immune evasion mechanism.

156 We also directly compare the innate immune evasion mechanisms between arenaviruses and other hemorr

157 atory disorders, in-depth knowledge of novel evasion mechanisms could direct future development of th

158 The human cytomegalovirus developed distinct evasion mechanisms from the cellular antiviral response

159 Leishmania parasites utilize adaptive evasion mechanisms in infected macrophages to overcome h

160 Below we discuss immune evasion mechanisms in leukemia and lymphoma, highlightin

161 thogens, whereas their involvement in immune evasion mechanisms is prominent among pathogens that est

162 vaccines to combat the highly sophisticated evasion mechanisms of pathogens.

163 Observations: Immune evasion mechanisms of these viral infections have an imp

164 udy suggests that EAV employs complex immune evasion mechanisms that warrant further investigation.IM

165 nce determinants, biofilm growth, and immune evasion mechanisms, comparatively little is known about

166 defy immune exclusion through sophisticated evasion mechanisms, including activation of host immunos

167 geted by Nef- and Vpu-dependent viral immune evasion mechanisms.

168 complements the known PRRSV-mediated immune-evasion mechanisms.

169 hts regarding the pathogen's possible immune evasion mechanisms.

170 suggesting existence of complementary immune evasion mechanisms.

171 s is associated with colonization and immune evasion mechanisms.

172 at NLRC5 is a major target for cancer immune evasion mechanisms.

173 ns, an increasing number of uniquely evolved evasion molecules have been discovered over the past dec

174 We recovered the known immune evasion molecules PD-L1 and CD47, and confirmed that def

175 ns persist because of virally encoded immune evasion molecules that inhibit antiviral responses.

176 , despite the presence of CMV-encoded immune evasion molecules.

177 h suggests the presence of phagosomal immune evasion molecules.

178 nd that cHLs have a genetic basis for immune evasion: near-uniform copy number alterations of chromos

179 nistic differences in replication and immune evasion observed for MARV and EBOV.

180 In fish, evasion of a diving bird that breaks the water surface d

181 e cells, which might both promote the immune evasion of Acanthamoeba and limit the induced inflammato

182 he maintenance of chronic infection involves evasion of adaptive immunity by antigenic variation(7).

183 s locus are not the sole mediators of immune evasion of African malaria parasites.

184 mechanism by which the virus can facilitate evasion of an immune system.

185 BDBV survivor, suggesting a role for sGP in evasion of antibody neutralization in the context of a h

186 ns modulated by NPM-ALK are also involved in evasion of antitumor immune response, protection from hy

187 r mRNA stability, efficient translation, and evasion of antiviral innate immunity in host cells.

188 Evasion of apoptosis allows many cancers to resist chemo

189 ncer whose overexpression contributes to the evasion of apoptosis and is one of the major resistance

190 t regulation of BCL-2 family members enables evasion of apoptosis and tumor resistance to chemotherap

191 Evasion of apoptosis is a hallmark of cancer.

192 A hallmark of cancer is the evasion of apoptosis, which is often associated with the

193 f the hallmarks of cancer is the blockade or evasion of apoptosis.

194 tic targets as a result of their role in the evasion of apoptosis.

195 Interfering with HIV-1's evasion of APP-mediated restriction also suppresses HIV-

196 ed in the natural design of human microbiome evasion of C. difficile, and this method may provide a p

197 Evasion of cell death is a key hallmark of cancers.

198 Our findings point to a mechanism of immune evasion of cells with a mesenchymal phenotype and sugges

199 at the blebbishield emergency program drives evasion of chromosomal instability and phagocytosis chec

200 Evasion of complement function is a hallmark of invasive

201 Evasion of complement-mediated opsonophagocytosis enable

202 , the virulence factor and the mechanisms of evasion of DC maturation remain unknown.

203 if the capsule of C. gattii was involved in evasion of DC maturation.

204 nsp15), an endoribonuclease, is required for evasion of dsRNA sensors.

205 al loss of mercury via brine drainage or gas evasion of elemental mercury.

206 objects associated with monetary reward, the evasion of equivalent loss, or neither of these.

207 pose that gain should have the same value as evasion of equivalent loss.

208 protein UL46, and that function involves the evasion of foreign DNA-sensing pathways.IMPORTANCE Herpe

209 Evasion of forkhead box O (FOXO) family of longevity-rel

210 te are likely mechanisms contributing to the evasion of herd immunity.

211 cular mimicry by HIV-1 Env that promotes the evasion of host anti-HIV-1 Ab responses can be directed

212 cellular resources for viral replication and evasion of host antiviral immune responses, it poses a c

213 trate that coronavirus nsp15 is critical for evasion of host dsRNA sensors in macrophages and reveal

214 for replication of the viral genome and for evasion of host immune responses.

215 lation of carriage and virulence traits, and evasion of host immunity.

216 non-human infectious trypanosomes, allowing evasion of human innate immunity.

217 -host interactions involved in induction and evasion of IFN represent a fertile area of research due

218 These results suggest gp68 contributes to evasion of IgG-mediated immune responses by mediating de

219 cancer (NSCLC), supporting the premise that evasion of immune destruction is of importance for NSCLC

220 tic niches, maintenance of inflammation, and evasion of immune surveillance.

221 eading to overexpression of PD-1 ligands and evasion of immune surveillance.

222 ys important roles in genome replication and evasion of innate recognition of viral RNAs by cellular

223 f HIV-1 in the cytoplasm of target cells and evasion of innate sensing mechanisms in macrophages.

224 essing of objects associated with reward and evasion of loss should be prioritized relative to neutra

225 epresentation of stimuli associated with the evasion of loss were degraded.

226 cluding stimuli that are associated with the evasion of loss.

227 rred not only through gain, but also through evasion of loss.

228 similarly for entry into the host cells and evasion of lysosomal fusion, the mutant was impaired in

229 If PEGylation can be proved to promote evasion of microglia, then this information will be of h

230 ypes for enhancement of AAV transduction and evasion of Nab recognition without increasing capsid ant

231 s a quantitative, mutation-level view of Env evasion of neutralization.

232 These results indicate that leukemic evasion of NK cell surveillance occurs through miR-media

233 nregulation of ULBP ligands for NK cells and evasion of NK-cell-mediated clearance.

234 ry increases odds for mistranslation through evasion of one but not both tRNA synthetase editing syst

235 ding to more effective feeding and potential evasion of predators.

236 hat the mutant DeltaFon1SIX6 protein allowed evasion of R protein-mediated host resistance.

237 pired nanoparticle surface design may enable evasion of specific components of the immune system and

238 flammation in the tumor microenvironment and evasion of the antitumor effector immune response are tw

239 nd is absolutely necessary for the efficient evasion of the Brucella-containing vacuole from the phag

240 e that peroxisomes constitute a platform for evasion of the cellular antiviral response and that the

241 totic and proliferation programs, as well as evasion of the host immune response.

242 arcinogenesis, with an emphasis on the viral evasion of the host immune system, and discusses how to

243 regulated in many cancers and contributes to evasion of the host immune system.

244 semination throughout the host organism, and evasion of the host's innate immune response.

245 tion has also been proposed to mediate viral evasion of the humoral immune response, though the mecha

246 ble for extensive damage to host tissues and evasion of the immune system response; they are major co

247 unique feature that has been associated with evasion of the immune system, while increasing spike den

248 to host cells, invasion of host tissues, and evasion of the immune system.

249 eria, and are involved in the modulation and evasion of the immune system.

250 isoforms has possible implications in immune evasion of the obligate pathogen T. pallidum during infe

251 ts a potential active site modulating immune evasion of the Plasmodium parasite across patients.

252 We propose that this mechanism allows evasion of the trade-off between cell occupancy by mitoc

253 findings indicate that KSHV RTA facilitates evasion of the virus from the immune system through mani

254 autolysosome generation, thereby leading to evasion of this important innate immune defense mechanis

255 enic drift of circulating strains enable the evasion of virus-inhibiting antibody responses, resultin

256 Persistent viral infections result from evasion or avoidance of sterilizing immunity, extend the

257 social environment, such as corruption, tax evasion or political fraud, can compromise individual in

258 n tumor cells is sufficient for tumor immune evasion or simply correlates with an inflamed tumor micr

259 ll characterized and knowledge of the immune evasion pathways exploited by these malignancies has gro

260 This method of immune evasion poses a challenge for the development of HCV vac

261 However, the immune evasion principles underlying serum resistance inA. baum

262 (TME), have emerged as key players in immune evasion programs that differentially control the fate of

263 he structural strength, motility, and immune evasion properties of the infective sporozoites.

264 provide the sporozoites not only with immune evasion properties, but also with lubricating capacity r

265 ccinia virus (VACV) encodes an innate immune evasion protein, E3, which contains an N-terminal Z-nucl

266 is and malignant tumors, harbors many immune-evasion proteins that manipulate the adaptive and innate

267 s in the world; and it was revealed that the evasion rates of CO2 and CH4 in tributaries of the river

268 impact of this process on successful immune evasion, remain unclear.

269 ylococcus aureus has highly efficient immune evasion strategies for causing a wide range of diseases,

270 standing of the immunosuppression and immune evasion strategies of these deadly viruses may guide the

271 such results are confounded by inflammasome-evasion strategies of vertebrate-adapted pathogens.

272 s (Env), gp120 and gp41, have evolved immune evasion strategies that render the elicitation of effect

273 , our data further confirm that viral immune evasion strategies that target MIRRs can be transferred

274 erculosis infection that orchestrates immune evasion strategies through the induction of NQO1 and TRX

275 1 (HSV-1), have evolved a variety of immune evasion strategies to avoid being detected and destroyed

276 Unfortunately, many cancer cells use immune evasion strategies to avoid their eradication by the imm

277 onses is a prominent feature of viral immune evasion strategies to prevent premature clearance of inf

278 or of viral infections and a target of viral evasion strategies, regulating cell death, inflammasome

279 class I has been described as a major immune evasion strategy in many cancers.

280 These data suggest an evasion strategy in which Ct presents a large panel of i

281 ory cytokine secretion, perhaps as an immune evasion strategy or to postpone cytokine-induced reactiv

282 or, and highlights a potential innate immune evasion strategy that may be employed by other bacterial

283 In conclusion, using a viral immune evasion strategy that shows broad immune-ablating activi

284 A common evasion strategy used by diverse pathogens is the hijack

285 This study characterizes an immune-evasion strategy used by malaria parasites and highlight

286 nt and drug sensitivity identified an immune-evasion subtype that showed increased sensitivity to nuc

287 Focusing on the immune-evasion subtype, bioinformatic analysis of microRNA prom

288 and downregulation of miR-29b in the immune-evasion subtype.

289 deploys GIF, a member of the poxvirus immune evasion superfamily, to antagonize GM-CSF (granulocyte m

290 sting that it represents an additional viral evasion/survival strategy.

291 ns of these loci, structural bases of immune evasion that are shared with PMBL.

292 between genomic instability and phagocytosis evasion that is coordinated by the blebbishield emergenc

293 inK alleles promoted colonization and immune evasion that were mediated by cell-associated matrices i

294 fuels inflammation and supports tumor immune evasion, thereby serving as an immunological driver of t

295 Evasion through immunomodulation is one of the several s

296 pe and suggest a strategy to overcome immune evasion through induction of the immunoproteasome to inc

297 bishield emergency program, and phagocytosis evasion to offer poor prognosis.

298 Stream methane is lost as evasion to the atmosphere or in-stream methane oxidation

299 opes on viral envelopes vulnerable to immune evasion will aid in defining targets of vaccine immunoge

300 n of mechanisms underlying CAR T cell immune evasion within the tumor microenvironment for the improv