ライフサイエンスコーパス: evidence

1 .01 d [95% CI, -2.67 to 2.69 d]; low-quality evidence).

2 equired in the face of indeterminate sensory evidence.

3 decisions are based only on the most recent evidence.

4 icism abounds because of the lack of level 1 evidence.

5 method to evaluate and grade the quality of evidence.

6 Based on available evidence, a working diagnostic algorithm is proposed tha

7 thodological maturity to provide substantial evidence about such representations.

8 ndings suggest that EL is driven by a latent evidence accumulation process that can be revealed with

9 Incorporation of proteomic evidence allowed us to change the designation of more th

10 ers with expertise in guideline development, evidence analysis, and family-centered care to revise th

11 Joint Task Force, the workgroup reviewed the evidence and developed recommendations about initial tre

12 L Academic Research Consortium met to review evidence and make recommendations for assessment of dise

13 aded according to the strength of underlying evidence and potential benefit gained by early detection

14 This guideline grades the evidence and recommendations by using the ACP grading sy

15 4 [95% CI, 0.62-1.42]; p = 0.77; low-quality evidence), and no change in the duration of mechanical v

16 ak recommendations and to classify levels of evidence as high, moderate, low, or very low.

17 h results from recent studies strengthen the evidence base for the efficacy and safety of sublingual

18 This strategy could strengthen the evidence base to enable black women to fully benefit fro

19 For multi-use to be acceptable, evidence based guidelines must be available for healthca

20 care are poorly correlated with provision of evidence-based care in these 4 clinical services.

21 egically the ABCDEF bundle through team- and evidence-based care.

22 y of, and yield after, provider overrides of evidence-based clinical decision support (CDS) for order

23 of customized dosing regimens through either evidence-based dosing nomograms or preferably through th

24 To provide ICU clinicians with evidence-based guidance on safe medication use practices

25 y for Radiation Oncology (ASTRO) produced an evidence-based guideline on radiation therapy for gliobl

26 y for Radiation Oncology (ASTRO) produced an evidence-based guideline on radiation therapy in orophar

27 An evidence-based optimised dose regimen was constructed th

28 RATIONALE: The development of evidence-based treatment guidelines for pediatric pulmon

29 in primary care needed to assure efficient, evidence-based, and quality health care.

30 tion in HEY, A2780, and A2780/Taxol cells as evidenced by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl t

31 ardiac hypertrophy and systolic dysfunction, evidenced by a 5-fold greater heart mass, 60-90% reducti

32 This is evidenced by accumulation of p62 and downregulation of L

33 tively binds to TrkB/C receptors in vivo, as evidenced by entrectinib blocking studies.

34 m treatment results in continued benefit, as evidenced by improved symptom control and reduced exacer

35 Adaptation to the cells was evidenced by increase in progeny production.

36 tedly, the sympathoactivation at HA that was evidenced by increased circulating noradrenaline concent

37 on site and to oxidize Co(II) to Co(III), as evidenced by operando X-ray absorption spectroscopy at t

38 type HIV-1 infection despite good adherence, evidenced by repeatedly high concentrations of tenofovir

39 osphorothioate modified ASOs in the liver as evidenced by the loss of activity of GalNAc conjugated a

40 growth of Lactobacillus reuteri C1 strain as evidenced by the optical density of the culture broth.

41 hly sensitive to proper fuel availability as evidenced by the rapid decline in neuronal function duri

42 The versatility of this method is evidenced by the realization of nanocavities obtained by

43 ent connection to the underlying lattice, as evidenced by the small magnitude of the magnetostriction

44 intracellular parasite Trypanosoma cruzi, as evidenced by transcriptome and cytometry analyses in mix

45 t domain pair and the IgG1 CH3 homodimer was evidenced by X-ray crystallography and used to engineer

46 Recent evidence challenges the MD view by demonstrating that a

47 Current evidence continues to support the benefits of an earlier

48 Despite extensive evidence demonstrating the beneficial effects of statins

49 mentary makes three points: (1) the existing evidence does not consistently favor the proposed sex di

50 Finally, the available evidence does not support the view that the globalizatio

51 Last, we will assess whether evidence exists in the literature that transformation mi

52 Conflicting evidence exists on the effects of fructose consumption i

53 solation facility use; however, insufficient evidence exists to support its use over standard clinica

54 Our results therefore provide strong evidence for a contemporary sexual arms race.

55 h as interpreting the visual signals so that evidence for a decision can be accumulated elsewhere.

56 These findings provide evidence for a dynamic neural transformation of low-leve

57 We also find evidence for a shift in vector species complex towards i

58 There was some evidence for a stronger association at higher turbidity

59 ACD1 are relevant models, and strengthen the evidence for a unifying pathogenesis in CNMs via defecti

60 Although there is some evidence for allergy-promoting effects in children becau

61 minous type Ia supernova has been claimed as evidence for an interaction between a red-giant or a mai

62 Six factors demonstrated strong strength of evidence for association with the primary outcome: age,

63 Overall, we found evidence for at least 13 independent mesopolyploidies fo

64 d extend earlier findings and strengthen the evidence for circulatory-disease mortality radiation ris

65 These results provide evidence for clinicians to consider with their patients

66 minal complement complex and provide in vivo evidence for contributions of complement-dependent membr

67 None of our results provided any evidence for dilation of the hP2X7R channel on sustained

68 everal antimycobacterial compounds; however, evidence for direct inhibition of MmpL3 activity is also

69 Remarkably, most show evidence for divergence in both yeasts.

70 These findings provide compelling new evidence for dynamic processing of speech sounds in the

71 These findings provide evidence for EAF2 as a key factor mediating androgen pro

72 LN chains in the human limbal niche provided evidence for enrichment of LN-alpha2, -alpha3, -alpha5,

73 es of extant species that are uncovering new evidence for evolutionary changes in the size and the nu

74 measures provide independent and converging evidence for functional organization into striped-based

75 Here, we present evidence for glucagon-like peptide 1 (GLP-1)-mediated pa

76 We provide the first evidence for heightened sympathetic outflow and reduced

77 We further find initial evidence for home-lab links: common noun "copresence" (i

78 Current evidence for HPM specialization is mostly indirect, deri

79 mational immunoassay, and provide supportive evidence for its application in the development of thera

80 ogene in different human cancers, but direct evidence for its role in tumorigenesis has been lacking

81 In this article we assess the evidence for nephrotoxicity and its possible mechanisms,

82 160 and XCL1 with biopsies with AMR provides evidence for NK cell CD16a activation in AMR.

83 At molecular level we provide evidence for non-canonical mode of action of Wnt5a and i

84 y crime scene and have been used as physical evidence for over a century.

85 ifying 13 mammalian genes for which there is evidence for polycistronic expression via translation th

86 Despite growing evidence for RNA-based regulation in meningococci, their

87 In contrast, similar evidence for seagrasses is sparse; the present study is

88 We found evidence for substantial common regulation and conservat

89 egate level (G); however, there is ambiguous evidence for the existence of g when analyzing data usin

90 These results bring strong evidence for the existence of mGlu2-4 heterodimers in na

91 tical spectroscopic and electronic transport evidence for the formation of an excitonic insulator gap

92 election in a gene is usually interpreted as evidence for the gene providing a function that is targe

93 We summarize the available evidence for the most commonly used and discussed CAMs.

94 er polarization and magnetic field, and find evidence for the paired Pfaffian phase that is predicted

95 Evidence for the percolation of metallic melt is provide

96 concepts are relevant to videos that contain evidence for the persistence of the Ivory-billed Woodpec

97 es and other alpha-synucleinopathies, direct evidence for the precise synaptic localization has been

98 At present, there is, however, insufficient evidence for the primary use of mTORis as protective age

99 Finally, we show evidence for the requirement of VASP to form tetramers a

100 We found strong evidence for the same genomic position being mutationall

101 Here we provide evidence for the usefulness of a Drosophila larva model

102 This provides evidence for the versatility of CCPs to control diverse

103 o be present in the human genome, but direct evidence for their biological function is scarce.

104 tic review and meta-analysis to evaluate the evidence for their use in this setting.

105 lls of the container, clear-cut experimental evidence for this prediction is lacking.

106 In this study, we present direct evidence for water dissociation equilibrium on rutile-Ti

107 Epidemiological evidence from developed countries indicates that Helicob

108 The accumulated evidence from literature points toward a future UWM that

109 Together with evidence from observational studies, our findings furthe

110 On the basis of our review of the cumulative evidence from RCTs designed to assess the effect of omeg

111 s on their individual perspectives regarding evidence gaps in current RSV epidemiology in the United

112 However, evidence has emerged that MPO-derived oxidants contribut

113 Available evidence has suggested that, in gestational weeks 32-39,

114 Increasing evidences have demonstrated that long noncoding RNAs (ln

115 ethodologists appraised the certainty in the evidence (i.e., the quality of evidence) using the Gradi

116 Multiple lines of evidence implicate chromatin in the regulation of premes

117 There is evidence implicating the role of female sex hormones as

118 ly bisphosphonates, and the absence of clear evidence in support of their long-term efficacy is leadi

119 and CVD reviews and discusses the scientific evidence, including the most recent studies, on the effe

120 several instruments with extensive validity evidence, including the Nontechnical Skills assessment,

121 Recent evidence indicates that lncRNAs play important roles in

122 This evidence indicates that modulation of hypothalamic GRP78

123 Preclinical and preliminary clinical evidence indicates that radiolabeled somatostatin (sst)

124 tochores and microtubules, and some in vitro evidence indicates that the phosphorylation of Dam1 prot

125 In the present study, we show evidence indicating that SIDT1 and SIDT2 not only do not

126 Nevertheless, evidence is accruing for broad, threat-neutral sensory h

127 We argue that their representation of the evidence is incomplete and that their theoretical propos

128 without neutropenia, but the quality of the evidence is low.

129 to diabetes, but at low-moderate levels the evidence is mixed.

130 Mechanistic and X-ray evidence is presented that supports that the reaction pr

131 erimental observations and DFT calculations, evidence is provided that these Mn(IV) species compropor

132 behaviour is probably important, but strong evidence is still lacking.

133 These findings provide new evidence linking cognition with WM via the reliance of n

134 Accumulating evidence links inflammation and atrial fibrillation (AF)

135 e updates will depend on the methodology and evidence model used by each guideline.

136 0 [95% CI, 0.25-1.01]; p = 0.05; low-quality evidence); no reduction in tolerance of enteral feeds (r

137 tion, for instance, makes qualities of their evidence, not observed directly, socially accessible.

138 We argue that the evidence now overwhelmingly favours an approach that tak

139 Despite this evidence of "silencing", intracellular free calcium imag

140 Our findings provide little evidence of a causal association between smoking initiat

141 Here, for the first time, we show robust evidence of a decrease in hail size using continuous and

142 There was no evidence of a threshold in the exposure-response relatio

143 d multiplicative predictive effects, with no evidence of an interaction (p = 0.329 and p = 0.291 for

144 an and Northeastern European populations and evidence of ancient gene flow from Siberia into Europe.

145 ld more enriched with drugs having published evidence of antiepileptic efficacy in animal models than

146 he LINCS database as either having published evidence of antiepileptic efficacy or lacking such evide

147 FITM3 SNP rs12252 with severe influenza, but evidence of association and the mechanism by which risk

148 count and ART duration), and there was some evidence of association with HSIL-CIN2+ (0.65, 0.40-1.06

149 Our results provide novel evidence of associations between exposure to some pestic

150 INTERPRETATION: No evidence of benefit for ketamine was found although the

151 Furthermore, we provide evidence of bilateral CSD recorded by fMRI during bilate

152 ry of cardiovascular disease, and radiologic evidence of cerebrovascular pathology.Higher concentrati

153 During late pregnancy, female mice show no evidence of chronic pain whatsoever.

154 iratory rate, consciousness level, and other evidence of clinical deterioration.

155 rch, a high proportion had neuropathological evidence of CTE, suggesting that CTE may be related to p

156 Furthermore, we found evidence of diet specialization with all fish maintainin

157 Evidence of directional pleiotropy averaged across all v

158 none of the available drugs has shown clear evidence of disease-modifying activity, even if some pat

159 these sites after 18 months, indicating how evidence of disturbance can be obscured in this environm

160 ntact fear and extinction learning, and show evidence of divergence in subjective, physiological, and

161 mutant and ERG-fusion organoid models showed evidence of divergent, rather than common, transcription

162 ult subjects undergoing cardiac surgery with evidence of early AKI to receive intra-aortic MSCs (AC60

163 Despite evidence of efficacy of team-based surgical safety check

164 In addition, we find evidence of epigenetic memory in the transdifferentiated

165 There is also evidence of herd protection against the vaccine-specific

166 There was some evidence of heterogeneity by tumor grade ( P = .02), wit

167 The two-step meta-analysis did not reveal evidence of heterogeneity of effect (I(2)=0.0, p=0.56).

168 cal evaluation showed larger lumen areas and evidence of higher biological activity (smooth muscle ce

169 al identity in vegetative tissues, providing evidence of how cell proliferation is controlled in an i

170 Conclusion These data show no overall evidence of improved survival with Cel.

171 There was no evidence of improvement in complete response within 1 ye

172 Furthermore, these results provide evidence of interactions between N deposition and temper

173 be shared among heterologous hosts providing evidence of interspecies transmission events.

174 Our results provide evidence of involvement of the mTORC1-HIF-1alpha pathway

175 No evidence of K-ras mutations was observed.

176 In patients with radiographic evidence of metastases and minimal symptoms, enzalutamid

177 There is evidence of much higher radiation-associated relative ri

178 but also to a cocktail of BDE congeners with evidence of neurodevelopmental toxicity.

179 used to assess for pathogen-specificity and evidence of nonspecific alloreactivity.

180 Thirty-one patients (36%) had evidence of NR, whereas 58 (67%) had MVO.

181 Although previous research shows evidence of numerical distance effects in the intraparie

182 of changes in amino acid properties provide evidence of positive selection on the ND2 and ND5 genes

183 The first evidence of prostate cancer lesion visualization in men

184 8 of 160 (42.5%) without a breast pCR had no evidence of residual nodal disease (P < .01).

185 Characteristics of their digits provide evidence of roosting behaviour, as in dermopterans and b

186 reatment of their metastatic cancer, who had evidence of serous retinal detachments confirmed by opti

187 We find evidence of significant differences between the two grou

188 five individuals with GRIA1 mutations shows evidence of specific learning disabilities and autism.

189 pite the high risk of compromised nutrition, evidence of the effect of refugee rations on fetal growt

190 f alcohol dependence, our study adds further evidence of the effect of the same genes on a cross-sect

191 In a comment on our Article "Evidence of the hydrogen release mechanism in bulk MgH2"

192 This study adds to the limited evidence of the protective effect of adherence to a Medi

193 Here, I review the evidence of whether mito-nuclear interactions are likely

194 ve inequality in income, the article reviews evidence on compounded deprivation, racial cleavages, ci

195 The current review assessed new evidence on the benefits and harms of folic acid supplem

196 ns from moderate, low, and very low level of evidence on the topics of: communication with family mem

197 Web of Science (ISI database), Physiotherapy Evidence (PEDRO) database, and ClinicalTrials.gov for th

198 Much genetic and physiologic evidence points to impaired arousal responses to hyperca

199 Mounting evidence points to specialized neuronal subtypes within

200 pathway is well characterized, accumulating evidence points to the existence of multiple, less well-

201 ation approach and summarized the results in evidence profiles.

202 Recent evidence recognizes the beta-arrestin system as a key re

203 The aim was to investigate available evidence regarding effectiveness and safety of surgical

204 exercise capacity, but there is conflicting evidence regarding its ability to improve physical activ

205 Consistently, new evidences reported glycosyltransferases in the blood, fr

206 atients with Major Depressive Disorder." The evidence review done for the guideline found no statisti

207 Multiple lines of evidence show that cold stadials in the North Atlantic w

208 We provide evidence showing asymmetric subgenome domestication for

209 Recent evidence shows that warm semi-arid ecosystems are playin

210 eir involvement could never be unambiguously evidenced spectroscopically.

211 mparator, Outcome questions, five quality of evidence statements, and one commentary on disclosure wa

212 largely unknown; however, multiple lines of evidence suggest that neural circuits supporting model-b

213 Several lines of evidence suggest that parvalbumin (PV+) interneurons are

214 Increasing evidence suggests a crucial role of inflammation in cyto

215 Further evidence suggests a thymic origin of these mutant ILC2s.

216 Emerging evidence suggests impulse control disorder subtypes have

217 Emerging evidence suggests novel roles for bacterially derived vi

218 Some evidence suggests that chronic kidney disease is a risk

219 Molecular and genetic evidence suggests that CPSF30-L works upstream of NRT1.1

220 However, preliminary evidence suggests that flicker may also entrain endogeno

221 Recent evidence suggests that glycemic control is associated wi

222 Evidence suggests that individuals with clonal haemopoie

223 Recent evidence suggests that NMDAR antagonists relieve depress

224 However, most evidence suggests that the domain immediately downstream

225 A significant body of evidence suggests that the highly dynamic Abeta oligomer

226 Emerging evidence suggests that the subcellular organization of c

227 Recent evidence suggests that these viruses are infectious, and

228 Recent evidence suggests value for both selective drain placeme

229 can be improved via the use of CBCT, limited evidence supported the use of CBCT imaging improving the

230 ry and genetics of LOX-1; describes existing evidence supporting the role of LOX-1 in atherogenesis a

231 Experimental evidence supporting this hypothesis shows that chronic e

232 Our results provide critical preclinical evidence supporting treatment of epilepsy and autistic-l

233 A growing body of evidence supports a link between androgen deprivation th

234 A growing body of evidence supports a strong link between neovascular dise

235 We did an evidence synthesis of health and social interventions fo

236 This exploratory study provides limited evidence that a short course of IVIG administered in the

237 t is, to our knowledge, the first conclusive evidence that ARPKD is not a homogeneous disorder and fu

238 Overall, our findings offer functional evidence that complement activation serves as a critical

239 in the enzyme active site; however, there is evidence that conformational restriction of the substrat

240 We found metagenomic evidence that cryptoendolithic microorganisms are adapte

241 These findings provide further in vivo evidence that distribution of the [18F]AV-1451 signal as

242 We provide evidence that Dnd1 protein, expression of which is low i

243 The authors present compelling evidence that early exposure to tanning beds advances th

244 We find no evidence that either MAC or PAC are associated with LTL

245 Altogether, our study provides direct evidence that endogenous Rspo2 and Rspo3 chromosome rear

246 In summary, we found no evidence that ERG is an effector of SPOP mutation in hum

247 issue of further interest given the mounting evidence that fetal growth in general is linked to degre

248 ificant increased risk of mortality provides evidence that GBS infection contributes to NE.

249 We found no evidence that gut microbe community composition was asso

250 ries (e.g., phonemes), providing qualitative evidence that human observers utilize information about

251 Here, we provide evidence that hypoxia causes economic impacts on a major

252 There was no evidence that iCST has an effect on cognition or QoL for

253 Our study provides genetic evidence that impairment of trophoblast-specific GATA2/G

254 This study provides robust evidence that increased vitamin B6 catabolism is indepen

255 Here, we present evidence that individual GPCR-G-protein interactions can

256 There is growing evidence that invasions foster eutrophication.

257 in vivo findings support our data, providing evidence that LDR is a promising option for future treat

258 dgements 536 References 536 There is growing evidence that life has been on land for billions of year

259 lving genetically inherited traits, and find evidence that malaria parasitemia does contribute to the

260 Here we present evolutionary evidence that minor-group viruses are also more immunoge

261 Here we present evidence that Myo2p, not Myp2p, is likely to be the majo

262 In aggregate, these findings provide evidence that nutrient stoichiometry is a strong predict

263 We provide evidence that once technological macaques reach a large

264 e widely used in consumer products, there is evidence that particle size and formulation influences s

265 s of mind perception has been interpreted as evidence that people consider mental life to have two co

266 Here, we have provided evidence that RANKL controls the expression of 3BP2, an

267 We found molecular and genetic evidence that reductions in Reln expression contribute t

268 We provide evidence that RIM1alpha and RIM1beta are highly likely a

269 We then review evidence that self-related and social considerations are

270 This study provides evidence that shortened telomere length is associated wi

271 To our knowledge, this is the first evidence that some mammals can use an inverted order of

272 Our study provides evidence that some sponges can tolerate environments tha

273 We also provide evidence that substrate-transport elicited endocytosis o

274 We also present evidence that susceptibility of trees to H. fraxineus is

275 This study provides evidence that the dynamic wound microbiome is indicative

276 vioral action of NPS, and present a chain of evidence that the effects of NPS within the hypothalamic

277 These genetic findings provide additional evidence that the microglia-mediated innate immune respo

278 We provide evidence that the risk-associated SNPs are associated wi

279 of human and murine data provides compelling evidence that the T2D risk associated with variation at

280 STATEMENT: Decades of research have provided evidence that the ventromedial prefrontal cortex (vmPFC)

281 uality of the prediction provides compelling evidence that these subjective reports correspond to the

282 First, evidence that thrombin may be as important as platelets

283 he results of this study provide preliminary evidence that use of e-cigarettes with higher nicotine c

284 In this study, we present the first evidence that using a BCI-FES system, a human with tetra

285 To synthesize and assess the quality of the evidence to address 3 research questions: (1) How accura

286 th may diminish the benefit, and there is no evidence to recommend screening in this group.

287 Here, we provide mass spectrometric-based evidence to show that metallodrug interactions with prot

288 However, there is growing evidence to suggest that glucuronides can be ligands of

289 y underlying this proposal and the empirical evidence to support it.

290 Conclusion This study provides evidence to support no overall outcome benefit from adju

291 We believe there is sufficient evidence to support referring or daily monitoring of chi

292 eractions in fact did exist, we did not find evidence to support the claim that supplementation leads

293 ounts for sex differences, but there is also evidence to support underlying genetic variance.

294 Our findings add additional evidence to the link between defects in genes that regul

295 rces, with most studies focusing on indirect evidences, ultimately affecting our interpretation on ho

296 A great body of evidence unveiled the existence of different stem cell t

297 tainty in the evidence (i.e., the quality of evidence) using the Grading of Recommendations, Assessme

298 Strength of evidence was rated by group consensus.

299 ce of antiepileptic efficacy or lacking such evidence, we demonstrated that our set of repurposable d

300 auses of its sensations by combining sensory evidence with internal predictions based on available pr