ライフサイエンスコーパス: evidence implicating

1 These observations provide the first evidence implicating a Bcl-2 family member in the regula

2 ate disease phenotypes are numerous, yet the evidence implicating a causal relationship of these resp

3 ineffective cytoskeletal reorganization with evidence implicating a downregulation of expression of t

4 dings point to a cancer syndrome and provide evidence implicating a germline mutation in ATR and susc

5 provides the first molecular and functional evidence implicating a GJA1 mutation as a novel pathogen

6 We will discuss evidence implicating a key role for endothelial cells th

7 le steps of ribosome biogenesis, and provide evidence implicating a mammalian RNA helicase in RNA mod

8 the Spo0 phosphorelay, there is considerable evidence implicating a mechanism of post-translational c

9 ng the past several years, numerous lines of evidence implicating a multistep process of malignant tr

10 asis for this disease has been challenged by evidence implicating a number of divergent etiologic fac

11 Despite mounting genetic evidence implicating a recent origin of modern humans, t

12 Moreover, we provide evidence implicating a requirement for NFkappaB transcri

13 Thus, these results provide genetic evidence implicating a requirement for PKR in mediating

14 There is compelling evidence implicating a role for ACAT1 in macrophage foam

15 The evidence implicating a role for calcineurin signaling in

16 Furthermore, we address the evidence implicating a role for PCP components in ciliog

17 Whereas there is strong evidence implicating a role for phosphorylation of UBF i

18 Here, we provide evidence implicating a role for proline oxidase in renal

19 d its association with AD adds to increasing evidence implicating a role for the innate immune system

20 We describe multiple lines of evidence implicating a trichome-expressed gene from this

21 The evidence implicating a vascular cause in OAG is mounting

22 gether, these observations provide the first evidence implicating abnormal tau in the neurodegenerati

23 These results provide initial evidence implicating abnormal tryptophan/kynurenine path

24 ink is of special interest, because there is evidence implicating actin dynamics in endocytosis.

25 This study provides the first evidence implicating ADAMTS-5 in the regulation of prote

26 This study provides the first evidence implicating aggrecan and aggrecanases in the va

27 d proteomic studies have provided convincing evidence implicating alterations in immune/inflammatory

28 In addition, although we do not find evidence implicating altered proliferation in the rescue

29 The genetic evidence implicating amyloid-beta in the initial stage o

30 ECENT FINDINGS: There is a gathering body of evidence implicating an energy-deficient state in the pa

31 These data also provide the first evidence implicating an important function of Rab26 in c

32 n together, these observations provide novel evidence implicating an important role of autophagy and

33 Our study provides new evidence implicating an important role of THP in influen

34 ovide the first in vivo electrophysiological evidence implicating an L-type calcium channel that modu

35 They review evidence implicating atrial cardiomyopathy as an indepen

36 tively, the data presented provide the first evidence implicating B7-H1 in the suppression of host im

37 provide a biological explanation for recent evidence implicating beclin 1 in human cancer and sugges

38 These results corroborate recent clinical evidence implicating beta-cell dysfunction in the pathop

39 Recent evidence implicating both G alpha12 and G alpha13 in the

40 specific endonuclease and are congruent with evidence implicating both hRad52 and XPF/ERCC1 in a numb

41 There is considerable evidence implicating both the glomerular basement membra

42 To review the evidence implicating C pneumoniae in the pathogenesis of

43 These results provide genetic evidence implicating calcineurin as an important mediato

44 This article reviews the evidence implicating calcium and cAMP as central players

45 These data provide evidence implicating CD4(+) T-cell cytokines in the path

46 Together, the data provide direct evidence implicating CDH23 and PCDH15 proteins in the fo

47 classical and recent advances, including new evidence implicating CENP-A chaperones in this conflict.

48 Evidence implicating CEs in carcinogenesis, in particula

49 Consistent with this, there is increasing evidence implicating chloride in a range of neurological

50 We also review the current body of evidence implicating chromatin modifications and RNA mol

51 There is evidence implicating chromatin remodeling proteins in he

52 Despite strong genetic evidence implicating CLEC16A in autoimmunity, this gene'

53 enriched in cancer genomes, but experimental evidence implicating condensin dysfunction in tumorigene

54 Evidence implicating dCK in cancer cell proliferation an

55 These data provide strong genetic evidence implicating de novo synthesis of Ang II in the

56 In this issue, Duan et al. present evidence implicating DISC1 in the maturation and integra

57 Here, we discuss the evidence implicating disruption of the catecholamines (d

58 Here we provide evidence implicating DOCK180 in netrin signal transducti

59 In light of the clinical evidence implicating dopamine in schizophrenia and the p

60 In light of evidence implicating dopamine in the pathophysiology of

61 These results provide evidence implicating dorsal striatum in higher-level org

62 There is extensive evidence implicating dysfunctions in stress responses an

63 We also review evidence implicating each of the above MYC genes in spec

64 Coupled with recent evidence implicating ecdysone signaling in these embryon

65 In this review, we examine the evidence implicating endoplasmic reticulum dysfunction i

66 There is evidence implicating endoplasmic reticulum stress in the

67 These observations provide cogent evidence implicating endothelial KLFs as essential in vi

68 Evidence implicating energy defects in neurodegenerative

69 Epidemiological evidence implicating epigenetic factors includes complex

70 association studies discoveries, and provide evidence implicating epigenetic regulation of reverse ch

71 before developing an addicted phenotype with evidence implicating estradiol as a potential mechanism.

72 Evidence implicating estrogen as a key breast carcinogen

73 It is also based on evidence implicating excessive NMDA activity in MCS.

74 s preclinical evidence and indirect clinical evidence implicating gamma-aminobutyric acid (GABA) in t

75 s and in rare human diseases, and we examine evidence implicating genetic variations in lipin genes i

76 Our findings, together with previous evidence implicating H2A.Z in transcriptional regulation

77 ene has a key role in epilepsy, but clinical evidence implicating HCN1 mutations in human epilepsy is

78 Our novel evidence implicating helix III differs from evidence tha

79 We now provide evidence implicating hepatic epithelial-derived cytokine

80 ing and memory have provided a great deal of evidence implicating hippocampal mechanisms in the initi

81 Evidence implicating human chromosomes as a site for a g

82 There is increasing evidence implicating human epidermal growth factor recep

83 we examine the origins of gHAT epidemics and evidence implicating human genetics in HAT epidemiology.

84 Together with recent genetic and therapeutic evidence implicating IL-23, these findings suggest a gen

85 Despite strong evidence implicating immune dysfunction and genetic pred

86 This finding generates new evidence implicating increased procoagulant activity and

87 Evidence implicating individual gene polymorphisms (or h

88 Recently, evidence implicating individual genes within some of the

89 The evidence implicating infectious causation suggests that

90 Because of the evidence implicating inflammation in the pathogenesis of

91 nging now because there is a growing body of evidence implicating inflammatory cells at every stage o

92 On the basis of considerable evidence implicating inflammatory mediators in the progr

93 lerosis (MS) susceptibility; however, strong evidence implicating intrinsic and environmental factors

94 There is an emerging body of evidence implicating iron in carcinogenesis and in parti

95 rmation tropism in vitro and provides strong evidence implicating its contribution to the distinct pa

96 e alloimmune response, there is considerable evidence implicating lipoprotein abnormalities, metaboli

97 consistent with genetic and cell biological evidence implicating LPPs as negative regulators of lyso

98 ies functional heterogeneity consistent with evidence implicating lymphoid DCs in the negative select

99 obable, or possible according to strength of evidence implicating M. pneumoniae.

100 Here we discuss recent evidence implicating macrophages in HIV-1-mediated disea

101 These results provide further evidence implicating MAPK signaling factors as obligate

102 Despite a growing body of evidence implicating membrane interaction in IAPP toxici

103 Although there is strong evidence implicating MHC class II alleles and CD4(+) T c

104 In light of recent evidence implicating miR132 dysregulation in Rett syndro

105 In summary, this work provides direct evidence implicating miRNA in the process of turning on

106 have a functional ancestor in MreB based on evidence implicating MreB as an organizer of cell wall s

107 This review will discuss the evidence implicating mRNA translation as an important do

108 Clinical evidence implicating mucosal allergic responses in dysmo

109 Here we present evidence implicating mutations in the gene encoding alph

110 These findings extend the body of evidence implicating mutations in the hairless gene as a

111 Despite strong biochemical evidence implicating NAIPs in specific detection of bact

112 In particular there is fairly direct evidence implicating neuronatin in the causation of Lafo

113 nt genetic, pharmacological and neuroimaging evidence implicating neuropathology associated with psyc

114 This review discusses the evidence implicating neurotrophins as molecular mediator

115 el roles for NF-kappaB, together with recent evidence implicating NF-kappaB in the regulation of neur

116 There is considerable functional evidence implicating norepinephrine in modulating activi

117 These results provide direct evidence implicating O2(-) generation in the pathway to

118 hese data represent the first line of direct evidence implicating one of the organic anion transporte

119 tinnitus is unclear, especially in light of evidence implicating other networks, including the limbi

120 Evidence implicating oxidative stress in the pathogenesi

121 Genetic evidence implicating packaging elements as independent u

122 Although in animals there is direct evidence implicating particular miRNAs in the control of

123 Whereas the epidemiologic evidence implicating PDGF in human tumors is strong, mal

124 imental atherosclerosis and provide indirect evidence implicating PDGF-BB and Sp1 as possible mediato

125 Recent studies provide strong evidence implicating Peptostreptococcus micros in the pa

126 Though there is compelling circumstantial evidence implicating PFO, the precise role of PFO in the

127 hermore, these studies provide important new evidence implicating PI 3-K in the regulation of integri

128 The evidence implicating PKA has come from bath application

129 Evidence implicating plasminogen (Plg), the zymogen of p

130 In this review, the evidence implicating PLD and PA in the regulation of mTO

131 When combined with recent evidence implicating Pol epsilon in leading strand repli

132 Although there is considerable evidence implicating posttranslational mechanisms in the

133 These results provide strong evidence implicating PP1 function in meiosis.

134 These findings add to the evidence implicating prefrontal dysmaturation in this di

135 There is accumulating evidence implicating prolonged ER stress in the developm

136 These results provide the first definitive evidence implicating Ptp4a3 in colon tumorigenesis and h

137 in BXH-2 acute myeloid leukemia is the first evidence implicating Rap1 signaling in myeloid leukemia.

138 Despite extensive evidence implicating Ras in cardiac muscle hypertrophy,

139 conclude that although there is significant evidence implicating Ras, RhoA, and Rac1 in hypertrophy,

140 Here, we present genetic and molecular evidence implicating RCI1A in the response to low temper

141 Evidence implicating reentry as a mechanism of cardiac a

142 This report provides the first evidence implicating roles for hepatic TSLP signaling, t

143 enance of synaptic connections and to obtain evidence implicating S100 beta in the apparent neurotrop

144 lts are, to our knowledge, the first genetic evidence implicating sarcomere-associated formins in the

145 with auxin-mediated cell expansion, genetic evidence implicating SAURs in cell expansion has not bee

146 sustained mechanical forces, with increasing evidence implicating Schwann cells as key mediators.

147 lication divergence dates provide additional evidence implicating segmental duplications as a major m

148 precisely localized deletion provides direct evidence implicating segmental exchange of MHC-encoded D

149 consistent with behavioral and physiological evidence implicating serotonin as an inhibitory modulato

150 This review discusses recent evidence implicating serotonin in the development of exp

151 on were studied to corroborate pharmacologic evidence implicating SERT in 2'-NH(2)-MPTP-induced serot

152 e-scale genetic studies have provided robust evidence implicating several novel susceptibility genes

153 sequencing study provides strong functional evidence implicating several specific variants as primar

154 Compelling evidence implicating SnToxA and SnTox1 in disease develo

155 These results add to the evidence implicating soil ameboid predators as important

156 There is emerging evidence implicating soluble oligomers, smaller protein

157 provides the opportunity to seek convergent evidence implicating specific chromosomal segments and g

158 Absence of evidence implicating specific food or beverage sources a

159 Given the accumulating evidence implicating Src family kinases in the transduct

160 Much of the evidence implicating Stats in these cellular processes c

161 The evidence implicating sun exposure in the etiology of mel

162 eural crest development are reviewed and the evidence implicating TBX1 and other genes on chromosome

163 There is substantial in vitro and in vivo evidence implicating tea polyphenols as chemopreventive

164 Accumulating evidence implicating telomere damage as a driver of age-

165 Despite evidence implicating TGFalpha in the development of mamm

166 These data are intriguing given growing evidence implicating the 5-HTT in the pathophysiology an

167 In a previous investigation, we obtained evidence implicating the alpha4/5 region of the type A d

168 We present evidence implicating the ANK repeats in the regulation o

169 These findings provide additional evidence implicating the behavior of the ribosome transl

170 Furthermore, we present evidence implicating the bifunctional, Hh signaling comp

171 This provides further evidence implicating the cerebellum in cognition and sug

172 Here we present evidence implicating the DNA methylation program in the

173 Our data provide strong evidence implicating the ER-to-Golgi traffic as a site f

174 om the ER to the Golgi and provide the first evidence implicating the ER-to-Golgi transport as a regu

175 These findings provide strong evidence implicating the excitatory system within hippoc

176 responsible for this important function, and evidence implicating the GBM is largely ignored or forgo

177 There is increasing evidence implicating the human NF1 gene in epithelial ca

178 acks of weakness and add support to previous evidence implicating the IIS4 voltage sensor in slow-ina

179 We review evidence implicating the increase of intracellular sodiu

180 , Gonzalez-Villalobos et al. present further evidence implicating the intrarenal renin-angiotensin sy

181 ation, which is consistent with accumulating evidence implicating the IPS in structuring sensory inpu

182 We also present evidence implicating the Lhx6 and Lhx7 LIM-homeobox gene

183 eview provides a perspective of the emerging evidence implicating the LT Network in the development a

184 Given recent evidence implicating the medial prefrontal cortex in ret

185 ntestinal barrier function, given the recent evidence implicating the microbiome, diet, and mucosal i

186 We now provide evidence implicating the neuregulin (NRG)-erbB receptor

187 Here, we show evidence implicating the nitric oxide (NO)/cGMP signalin

188 Here we present genetic and functional evidence implicating the novel A178D missense mutation i

189 Here we review evidence implicating the orbitofrontal cortex in such be

190 r, the protein was hyperphosphorylated, with evidence implicating the p38/mitogen-activated protein k

191 Here, we provide evidence implicating the planar cell polarity (PCP) path

192 Despite evidence implicating the Polycomb group protein, Eed (em

193 To date, despite the mounting evidence implicating the potential diagnostic/prognostic

194 s and footshock and add to a growing body of evidence implicating the rhinal cortical regions in asso

195 These findings add to the growing body of evidence implicating the RNA processing pathway in neuro

196 There is evidence implicating the role of female sex hormones as

197 itional multivoxel pattern analyses revealed evidence implicating the rostrolateral PFC in the repres

198 We have previously presented evidence implicating the side chains of L8, I44, and V70

199 herent cortical rhythms and provides further evidence implicating the syllable as a computational pri

200 The present study provides multiple lines of evidence implicating the tumor suppressor protein p53 in

201 Here, we present evidence implicating the two-pore domain, pH-sensitive T

202 Here we present two lines of evidence implicating the ubiquitin-proteasome pathway in

203 Given recent evidence implicating the urokinase plasminogen activator

204 renia, and family-based studies found modest evidence implicating the Val allele in schizophrenia ris

205 (fMRI) data from human volunteers, we found evidence implicating the ventrolateral prefrontal cortex

206 The finding converges with recent evidence implicating the VMPFC in emotional and autonomi

207 , Aspergillus fumigatus, based on increasing evidence implicating the yeast metacaspase Yca1p in apop

208 d clinicians alike because of the increasing evidence implicating their role in many biological proce

209 the last few years because of the increasing evidence implicating them as key regulators of the choic

210 e (ICE) protease family has led to extensive evidence implicating these enzymes in apoptosis.

211 ar particularly noteworthy based upon recent evidence implicating these structures in the generation

212 pment; however, there is little experimental evidence implicating this cellular mechanism in the path

213 f EBNA3C with ProTalpha and p300 provide new evidence implicating this essential EBV protein EBNA3C i

214 lular visual pathway, consistent with recent evidence implicating this pathway in fine-grained stereo

215 Additional evidence implicating this region in linguistic processin

216 o expend effort for rewards, consistent with evidence implicating this region in the processing of re

217 r results provide the first proof-of-concept evidence implicating TLR9-triggered inflammation in peri

218 is may be relevant for the growing amount of evidence implicating TORC2 in cancer development.

219 Recent evidence implicating transmembrane (TM) segment 7 of the

220 we present integrative RNA, DNA, and protein evidence implicating TREML4 in coronary artery calcifica

221 Now, as result of molecular evidence implicating two separate ligand-gated calcium c

222 Direct evidence implicating upstream signals and components tha

223 dy provides the first genomewide significant evidence implicating variants near the ADM gene on chrom

224 The accumulation of preclinical and clinical evidence implicating VEGF-A in the pathogenesis of neova

225 However, most evidence implicating VTA DA neurons in these functions i