ライフサイエンスコーパス: evolutionary distance

1 ecology of the strains in addition to their evolutionary distance.

2 a major obstacle for estimating indel-based evolutionary distance.

3 etween these genomes, independently of their evolutionary distance.

4 alignments of long genomic sequences at any evolutionary distance.

5 patterns of expression--changes unrelated to evolutionary distance.

6 by ET-MIp and best discerned within a short evolutionary distance.

7 ns, quality of the training data set and the evolutionary distance.

8 d a decline in recombination with increasing evolutionary distance.

9 nd little across organs, and simply reflects evolutionary distance.

10 isiae was tested and found to correlate with evolutionary distance.

11 ing maximum likelihood estimates of pairwise evolutionary distances.

12 overt sequence homologies and over extensive evolutionary distances.

13 imilarly for chicken-human and chicken-mouse evolutionary distances.

14 g their performance over both short and long evolutionary distances.

15 changeable between plants separated by large evolutionary distances.

16 osome segregation are conserved across large evolutionary distances.

17 sterious yet general phenomenon across great evolutionary distances.

18 and ancestral reconstruction to bridge large evolutionary distances.

19 plant genomes, even across relatively short evolutionary distances.

20 tion regulator can be conserved across large evolutionary distances.

21 pared in vivo binding data across a range of evolutionary distances.

22 servation of similar body plans across large evolutionary distances.

23 ast, and our findings may apply across large evolutionary distances.

24 are also likely to be conserved across large evolutionary distances.

25 distance between the plants, even to ancient evolutionary distances.

26 zation decisions to be based on contemporary evolutionary distances.

27 grammed cell death are conserved across wide evolutionary distances.

28 ips between sequence similarity E-values and evolutionary distances.

29 NA/target interaction maintained across long evolutionary distances?

30 ls to birds and mammals despite considerable evolutionary distance [1, 2].

31 Our results suggest that evolutionary distance alone is not a precise predictor o

32 Evolutionary distances among different amino acid sequen

33 expresses >80 different R2R3 Myb genes, and evolutionary distances among maize Myb(BRH) sequences in

34 The calculation of evolutionary distances among proteins and distances at t

35 nding the pool of LDOs while maintaining low evolutionary distance and a high level of functional rel

36 Despite the large evolutionary distance and differences in root radial pat

37 Despite the large evolutionary distance and extensive rewiring of individu

38 king conservation over >400 million years of evolutionary distance and frequently are located megabas

39 Thus, despite their evolutionary distance and limited sequence identity, bot

40 variation in enzyme concentration is due to evolutionary distance and may be nonadaptive.

41 transposon function over a relatively large evolutionary distance and suggests that the piggyBac sys

42 ls of nucleotide substitution for estimating evolutionary distances and hint at bright prospects for

43 es increased taxon sampling to overcome long evolutionary distances and identify putative hidden orth

44 otein sequences that are conserved over long evolutionary distances and thus are critically important

45 , binding divergence increased linearly with evolutionary distance, and CTCF binding profiles are div

46 by genes that have been conserved over vast evolutionary distances, and most organisms are able to f

47 allow comparisons between species at various evolutionary distances, and powerful splice signal model

48 titution rates, computations of the error of evolutionary distances, and simulations of molecular evo

49 ogous noncoding DNA for organisms a suitable evolutionary distance apart is a powerful tool for the i

50 in the study of molecular evolution because evolutionary distances are required for estimating the r

51 In spite of the evolutionary distance between algae and mammals, C. rein

52 leles were common and increased with greater evolutionary distance between allele group members.

53 m in retinylidene proteins spanning the vast evolutionary distance between archaea and humans.

54 For example, the evolutionary distance between chicken and human provides

55 erved in other baculoviruses suggest a large evolutionary distance between CuniNPV and lepidopteran b

56 e also developed a new method to measure the evolutionary distance between different cancers based on

57 We propose a method for estimating the evolutionary distance between DNA sequences in terms of

58 Here, we investigated the impact of the evolutionary distance between donor and recipient specie

59 (CCV) was utilized to calculate the pairwise evolutionary distance between genotypes.

60 20 to 59%), perhaps reflecting a significant evolutionary distance between lepidopteran and orthopter

61 Despite the evolutionary distance between M. smegmatis and M. tuberc

62 Given the evolutionary distance between parrots and primates, the

63 ily, superfamily, and fold) depending on the evolutionary distance between protein sequences.

64 Given the evolutionary distance between protozoans and vertebrates

65 edium lengths, our method recovers the known evolutionary distance between rat and mouse, 0.014 indel

66 ts human ortholog does not increase with the evolutionary distance between the proteins, indicating t

67 Given sufficient evolutionary distance between the two sequences, we achi

68 ative replicases despite >1 billion years of evolutionary distance between them.

69 s between these enzymes highlights the large evolutionary distance between them.

70 divergent species suggests that substantial evolutionary distance between these two species has not

71 However, the vast evolutionary distance between trypanosomes and the highe

72 Despite the large evolutionary distances between metazoan species, they ca

73 logenetic reconstruction and analysis of the evolutionary distances between NDV-Peru/08 and other iso

74 This matrix can then be used to calculate evolutionary distances between pairs of sequences in the

75 n a multiple sequence alignment, we estimate evolutionary distances between proteins measured in expe

76 However, a recent survey of evolutionary distances between Saccharomyces cerevisiae

77 asing of major and minor alleles, as well as evolutionary distances between samples, and are able to

78 oduce genome conservation--a novel metric of evolutionary distances between species that simultaneous

79 However, its utility largely depends on the evolutionary distances between the species involved.

80 species is in accordance with the estimated evolutionary distances between them and we find it to ap

81 Finally, distinctive features and evolutionary distances between these different viral sub

82 The evolutionary distances between these four groups were al

83 on gene orthology and paralogy across broad evolutionary distances, both of fundamental value and se

84 found that many tools worked well at shorter evolutionary distances, but fewer performed competitivel

85 stem are orthologously conserved across long evolutionary distances, but genes in these pathways evol

86 p, we find the best fit approximation of the evolutionary distances by Euclidian distances and thus r

87 , a new alignment-free method that estimates evolutionary distances by measuring the decay of exact s

88 undance data with genome-derived measures of evolutionary distance can provide a clear indication of

89 s sequence alignments with good estimates of evolutionary distances can be a valuable resource for mo

90 ns in prokaryotes and eukaryotes revealed an evolutionary distance consistent with that inferred from

91 orithm for automated classification based on evolutionary distance data was written in S.

92 ect interspecies chimera generation, such as evolutionary distance, developmental timing, and apoptos

93 que method, RED, that utilizes the ratios of evolutionary distances E(d) to distinguish between alter

94 nized in C. elegans, implying that over this evolutionary distance enough changes occurred in cis-reg

95 simplifies the exploration of its impact on evolutionary distance errors and relative-rate tests.

96 ALFRED-G is an alignment-free heuristic for evolutionary distance estimation between two biological

97 nce alignment, substitution model selection, evolutionary distance estimation, phylogeny inference, s

98 atory regions can retain function over large evolutionary distances, even though the DNA sequences ar

99 transferase activity is conserved over large evolutionary distance for these proteins.

100 increasingly used and relied on to determine evolutionary distances for the basis of rational hierarc

101 hylogenetic trees shows that branch lengths (evolutionary distances) for third codon positions in CG-

102 consensus sequences, suggesting substantial evolutionary distance from known avian strain sequences.

103 nymous differences than expected, suggesting evolutionary distance from known avian strains.

104 zebrafish are of particular interest as the evolutionary distance from non-ichthyic homologues is la

105 ot clear whether the mouse is at the correct evolutionary distance from the human to provide sufficie

106 se mRNAs often 'disappeared' with increasing evolutionary distance from the parental species.

107 ilies, even when from an organism at a great evolutionary distance from those in the analysis.

108 substitution matrices over a range of target evolutionary distances from 20 to 200 Point Accepted Mut

109 This yields more realistic estimates of evolutionary distances from amino-acid sequences, which

110 to each other than are genomes at equivalent evolutionary distances from non-gut environments, sugges

111 Despite the evolutionary distance, functional parallels exist betwee

112 Our analysis suggests that, at long evolutionary distances, gene essentiality is significant

113 f both butterflies and primates, spanning an evolutionary distance >500 million years.

114 Estimation of evolutionary distances has always been a major issue in

115 amete-specific protein conserved across vast evolutionary distances, has garnered considerable attent

116 f aging rate that are conserved over a broad evolutionary distance have now been identified.

117 Over long evolutionary distances, however, sequence-based methods

118 four cDNA-to-genome comparisons at different evolutionary distances (human-dog, human-mouse, human-ch

119 e, yet many are highly conserved across vast evolutionary distances, implying strong selection on the

120 rgence by a factor of 4, so that mouse-human evolutionary distance in terms of selectively neutral in

121 t than nucleotide substitutions, mouse-human evolutionary distance in terms of selectively neutral su

122 the transcriptional machinery across a large evolutionary distance in the regulation of small nuclear

123 to accommodate consistently a wide range of evolutionary distances in a comparison framework based u

124 Analysis of sequence substitutions and evolutionary distances in this data set revealed that mo

125 Moreover, as host evolutionary distance increases, reassortment is increas

126 ces, important calibration points to convert evolutionary distance into time, are lacking, however; Z

127 Evolutionary distance is traditionally modeled using glo

128 The matrix of evolutionary distances is a model-based statistic, deriv

129 A sequences from multiple species at varying evolutionary distances is a powerful approach for identi

130 e form of interactive phylogenetic trees and evolutionary distance matrices.

131 nism of action); Types (that largely reflect evolutionary distance measured by sequence similarity);

132 o distantly related teleosts separated by an evolutionary distance of 115-200 Myr.

133 have been conserved from fish to mammals, an evolutionary distance of 450 million years.

134 The evolutionary distance of the 1918 NP sequences from avia

135 n-defined supraclonal sets, we exploited the evolutionary distance of the chicken immune system and t

136 penalties behave as a function of the target evolutionary distance of the substitution matrix.

137 This analysis also allows measurement of evolutionary distances of different proteins.

138 It has been observed that the evolutionary distances of interacting proteins often dis

139 litates unbiased assessment of the impact of evolutionary distance on predictive power.

140 ise provides the greatest accuracy at higher evolutionary distances, out-performing both AlignFS and

141 he number of core genes, calculated pairwise evolutionary distances (p-distances) based on nucleotide

142 sal of amino acid replacements and, at short evolutionary distances, pervasive homoplasy.

143 od was developed that utilizes the ratios of evolutionary distances (RED) to distinguish between alte

144 tion of intron splicing signals across large evolutionary distances, reveal unexpected motif conserva

145 are present at orthologous genes across vast evolutionary distances, revealing a surprising level of

146 is and rice (Oryza sativa) despite the large evolutionary distance separating these plants.

147 tested on vertebrate comparisons at diverse evolutionary distances, sim4cc had significantly higher

148 hat of the human GRK2 gene, highlighting the evolutionary distance since the divergence of these two

149 From parsimonious calculations of evolutionary distances since speciation, ctt-11, ctt-12,

150 ot be neglected in calculations that rely on evolutionary distances, such as the confidence intervals

151 related organisms, variation across broader evolutionary distances suggests that only a few residues

152 Conservation across such evolutionary distances suggests that soyuz1 plays a cruc

153 on of intron-exon structure, even over large evolutionary distances, suggests that comparative method

154 on the specific target for evolution and the evolutionary distance that needs to be crossed.

155 Despite the considerable evolutionary distance that separates ubiquitin from GlUb

156 ssive repository of orthologs and associated evolutionary distances that was built using the reciproc

157 nged so extensively (and over a much smaller evolutionary distance) that its cis-regulatory sequence

158 Despite this evolutionary distance, the genomes of these two species

159 Despite their evolutionary distance, the Saccharomyces cerevisiae retr

160 These results indicate that at these evolutionary distances, the contribution of indels to se

161 results on correcting the estimation bias of evolutionary distances, the estimation of the pattern of

162 It is found that, despite their evolutionary distance, these eubacterial and vertebrate

163 Despite their evolutionary distance, these proteins share structural a

164 ance of the gene recognition system with the evolutionary distance (time) between the two genomes.

165 lation, development and human disease, whose evolutionary distance to all other currently sequenced f

166 between the number of interactions and their evolutionary distance to its orthologs in other organism

167 svirus (KSHV) gB sequences and had a shorter evolutionary distance to KSHV gB sequences than to any o

168 olate-based strategies, as they minimize the evolutionary distances to circulating strains.

169 ignment and maximum likelihood estimation of evolutionary distances to detect orthologs between two g

170 ET uses evolutionary distances to estimate functional distances

171 inds protein similarities across significant evolutionary distances using sensitive protein domain pr

172 eotide difference, amino acid difference and evolutionary distance, we constructed viral networks and

173 of disulfide bonds, and that spanned various evolutionary distances, were aligned.

174 Phylo SI is particularly efficient on short evolutionary distances where synteny footprints remain d

175 functional module can be conserved at great evolutionary distances, whereas the associated regulator

176 idue in a gap (q+r) changes as a function of evolutionary distance, while the gap extension penalty f

177 ven manage to compete favourably for general evolutionary distances with an alignment produced by Gen

178 based on maximum likelihood estimates of the evolutionary distances, with branch lengths then calcula

179 rochlorococcus strains that span the largest evolutionary distance within the Prochlorococcus lineage

180 However, based on synonymous evolutionary distances, X-linked genes in M. musculus fa