ライフサイエンスコーパス: evolve

1 ir properties can illuminate how new species evolve.

2 ow individually costly pro-group behavior to evolve.

3 fecting the fitness landscapes on which they evolve.

4 d, understanding of the disease continues to evolve.

5 nary developmental biology is how new traits evolve.

6 tion and transplantation systems continue to evolve.

7 ing manufactured the circulating strains can evolve.

8 sitoid wasps to study how new gene functions evolve.

9 ow the disposition to think analytically can evolve.

10 , prior to rate-limiting aryl migration, has evolved.

11 designed and how the canonical genetic code evolved.

12 ep in understanding how general intelligence evolved.

13 ferent methods of behavior modification have evolved.

14 how commonalities in the ways that they have evolved?

15 Exoskeletons have evolved 18 times independently over 550 MYA and are esse

16 to elevate metabolic and growth rates - had evolved 54 million years ago.

17 in, a Tbox transcription factor protein, has evolved a changed preference for a low-affinity, seconda

18 Seeds have evolved a mechanism to integrate environmental informati

19 Ectomycorrhizal (ECM) symbioses have evolved a minimum of 78 times independently from saprotr

20 wledgements 1024 References 1024 Plants have evolved a multilayered immune system with well-orchestra

21 Vertebrates have evolved a neuron-specific splice variant of C-Src, N1-Sr

22 Each new origin has evolved a new mycangium.

23 Consequently, bacteria have evolved a number of chemotactic strategies that consist

24 G protein-coupled receptors (GPCRs) have evolved a seven-transmembrane helix framework that is re

25 les are complex surface appendages that have evolved a tight, hierarchical regulation of expression.

26 sites, the causative agents of malaria, have evolved a unique cell division cycle in the clinically r

27 d from bacterial precursors that had already evolved a wide range of cytoskeletal functions.

28 ion, few studies show how ocean temperatures evolved across the deglaciation.

29 an ancestral plasmid, and that RctB may have evolved additional regulatory features.

30 specialising on specific resources, species evolve advantageous morphologies to increase the efficie

31 ting the hypothesis that aerobic respiration evolved after oxygenic photosynthesis.

32 Here, we report an example of how nature evolved alternative mechanisms to fine-tune the activity

33 Perennial plants have evolved an adaptive mechanism involving protection of me

34 Animals have evolved an array of pattern-recognition receptor familie

35 underway or on the horizon will continue to evolve and expand the footprint of telemedicine within o

36 RTDs will continually evolve and improve, a process that will be more efficien

37 nstrate how resistance to agonist toxins can evolve and that such genetic changes propel organisms to

38 identification of the main gaseous products evolved and intermediate compounds formed during the the

39 As therapeutics have evolved and multiplied in number, the tumor metrics crit

40 feature in gene regulatory networks, how it evolves and affects network structure and function is no

41 the rate at which GRNs and their subcircuits evolve, and to tie their evolution to paleoenvironmental

42 AAV variant generated by combining multiple evolved antigenic sites effectively evades polyclonal an

43 of secondary sexual characters suggests that evolving any costly trait or strategy will pay off and s

44 Meanwhile, evolving approaches toward physician reimbursement will

45 targeted arterial CO2 has the capability to evolve as an alternative to current pharmacologic vasodi

46 porter substrate specificities originate and evolve as new biosynthesis pathways emerge.

47 esults demonstrate that the mandible may not evolve as rapidly as the cranium and the mandible is not

48 oculogenital pathogen Chlamydia trachomatis evolved as a commensal organism of the human gastrointes

49 For instance, we show that TERF1 evolved as a telomere-binding protein in the common stem

50 anotal hypothesis, which suggests that wings evolved as an extension of the dorsal thorax, and the gi

51 liquid-ordered and liquid-disordered phases evolves as the chain length of the n-alcohol increases.

52 e our understanding of how the cancer genome evolves as the primary tumor migrates from its origin in

53 We find that the face and braincase evolve at similar rates in Gymnotiformes and the reverse

54 For example, all six strains evolved at 32 degrees C had mutations in nadR, whereas n

55 However, a population evolved at 37 degrees C for an additional 18,000 generat

56 indicate that distinct pathways for MMR have evolved at least twice in nature.

57 as also illuminated whether protein features evolved because of functional optimization, historical c

58 trophic bacterial clades are thought to have evolved before oxygenic photosynthesis emerged, includin

59 rce from microbial competitors are likely to evolve behaviours to control or manipulate the animal's

60 that balanced polymorphism and recombination evolve between a target locus that codes for a seasonall

61 se factors (RFs) in decoding stop codons has evolved beyond a simple tripeptide anticodon model.

62 There is now an evolving body of evidence suggesting that these aerosols

63 ected to evolve only when the B cell lineage evolving breadth is consistently capturing and presentin

64 sitively correlated with, but independent of evolving burst activity over time.

65 e form in cyanobacteria, RCA of chlorophytes evolved by integrating chloroplast transit peptide (cTP)

66 dvantage of the structural design principles evolved by nature.

67 osophila erecta even-skipped (eve) locus has evolved by testing its activity in the divergent D. mela

68 man vision is that the retina and brain have evolved circuitry to extract useful spatial and spectral

69 In evolving complex systems such as air traffic and social

70 Herein we summarize and review evolving concepts and provide a personal perspective on

71 We review key principles and evolving concepts in the care of MPM patients with a foc

72 hromosomes, we find that Y-linked genes have evolved convergent gene functions associated with testis

73 Newly evolved CREs are enriched in immune response and neurode

74 s that E- and P-cadherin expression patterns evolved differently between chick and mouse.

75 n a common grass ancestor, and the two genes evolved differently for gene structure, sequence, and ex

76 species, suggesting that TLR5 signalling has evolved differently in ruminants.

77 however, bacteria with multipartite genomes evolved distinct systems to initiate replication of seco

78 entry receptor, different AAV serotypes have evolved distinctive interactions with the same receptor.

79 Our approach has evolved dramatically in the past few decades, where nove

80 ma patients reveal how tumor and immunity co-evolve during anti-PD-1 therapy.

81 ction of specific resistance mechanisms that evolve during therapy.

82 Here we characterize how these viruses evolved during replication in cell culture and in experi

83 isruption of conserved regulatory mechanisms evolved during the transition to multicellularity to con

84 knowledge concerning how vascular morphology evolves during carcinogenesis.

85 moral and intertumoral genomic heterogeneity evolves during tumorigenesis.

86 represent anciently diverged haplotypes that evolved early during the radiation of Darwin's finches.

87 Here we report a robust oxygen-evolving electrocatalyst consisting of ferrous metaphosp

88 ;2 and SULTR2;1, which may additionally have evolved enhanced specificity for selenate over sulfate.

89 transcription is more bidirectional at newly evolved enhancers and promoter regions.

90 putational design to product release for the evolved enzymes.

91 ion, which establishes a role for 3'-UTRs as evolved eukaryotic operons.

92 This suggests that neuropeptide expression evolves faster than morphology, representing a possible

93 Genomic testing is a rapidly evolving field with an increasing number of choices for

94 the complexity of natural proteins that have evolved for function, not stability.

95 Subsequently, the synthesized Si nanosheets evolve from amorphous to nanocrystalline to crystalline

96 distant high-fitness genotypes more readily evolve from lower-fitness intermediates.

97 of the non-interacting lattice component can evolve from quasi-3D to quasi-1D, leading to strong Ferm

98 d where volumes with nearly perfect lattices evolve from structures filled with dislocations, and how

99 ategies to reduce human schistosomiasis have evolved from 'snail picking' campaigns, a century ago, t

100 Land plants evolved from an ancestral charophycean alga from which t

101 verse enzymatic functions and reactions have evolved from ancestral scaffolds is fundamental to under

102 nset and female preponderance appear to have evolved from human interactions with pathogens in the mi

103 The heterophylly, evolved from linear to toothed-ovate shape, showed the s

104 ents of its human host as the disease course evolves from one of asymptomatic nasopharyngeal carriage

105 Meanwhile, Mo geometry evolves from tetrahedral to octahedral on the edge, and

106 drostatic pressure, the magnetic state of Eu evolves from the canted antiferromagnetic structure in t

107 creting neutron star (NS) with a spin period evolving from 1.43 seconds in 2003 to 1.13 seconds in 20

108 nd cancer cells are continuous, dynamic, and evolving from the initial establishment of a cancer cell

109 nces outside of minimal enhancer regions can evolve functionally through mechanisms other than change

110 The study of newly evolved genes has long fascinated biologists, but large-

111 h as granule size and contrast) for the most evolved giant and supergiant stars is challenging becaus

112 a for image reporting of PSMA ligand PET are evolving given the expanding body of literature on physi

113 ination of a defined gradient of fMLP and an evolving gradient of LTB4, generated by cells in respons

114 Nature has evolved hierarchical structures of hybrid materials with

115 y introduced to Indiana turkeys, in which it evolved high pathogenicity.

116 Furthermore, neither primitive nor evolved hydrated Martian crust show noticeably different

117 pe glycoproteins (Env), gp120 and gp41, have evolved immune evasion strategies that render the elicit

118 Purpose To inform the evolving implementation of CancerLinQ and other rapid-le

119 ng synthetic biologists and general users to evolve improved biomolecules within approximately 7 week

120 e functional modules that have been shown to evolve in childhood and adolescence.

121 cates that influenza viruses can continue to evolve in galliform species, increasing their opportunit

122 n profoundly affect how bacteria compete and evolve in porous environments, the habitat where most ba

123 l to show how these mechanisms are likely to evolve in response to cultural phenomena, such as langua

124 e glycoproteins (Envs) of HIV-1 continuously evolve in the host by random mutations and recombination

125 while nodes in each layer do not necessarily evolve in unison.

126 This recently extinct order of mammals evolved in a context of important geological, climatic,

127 Glucose-aversion is a heritable trait that evolved in a number of German cockroach (Blattella germa

128 known of how unique PNG mechanisms arose and evolved in eukaryotes.

129 Air-breathing has evolved in many fish lineages, allowing animals to obtai

130 d remove halogens from organic scaffolds has evolved in nature.

131 te having only one toxin, RT017 strains have evolved in parallel from at least two independent source

132 XDR tuberculosis has evolved in several tuberculosis-endemic countries to dru

133 nt dispersal of desiccation tolerant spores, evolved in the ancestral land plant.

134 istance to anticancer or antimicrobial drugs evolves in a patient, highly effective chemotherapy can

135 olve the paradox of why cooperative breeding evolves in such different types of environments.

136 Headspace sampling of CO2 that evolves in the acid-catalyzed process and analysis by GC

137 toma metastasizes to leptomeninges and as it evolves in the face of radiation and cytotoxic chemother

138 ision of care only for advanced CKD is still evolving in many countries.

139 step mutations selected in yeast populations evolving in parallel in the presence of the antifungal d

140 Like the other multicellular kingdoms, Fungi evolved increased size, complexity, and metabolic functi

141 c effects, suggesting that parental care can evolve independently in males and females.

142 promoter shape as a molecular trait that can evolve independently of promoter strength.

143 on is split and the resulting subpopulations evolve independently, accumulating mutations over time t

144 structurally distinct antigen receptor genes evolved independently in jawless and jawed vertebrates.

145 Meanwhile, beekeeping evolved independently in Mesoamerica with the stingless

146 hylogenetic distribution implies these loops evolved independently, but their structural similarity s

147 eria, comprising different types that likely evolved independently.

148 dynamics can be sufficient for the virus to evolve intermediate viral loads consistent with maximisi

149 nd 3D-structured sheets are preprogrammed to evolve into bio-inspired shapes (lotus flowers and shark

150 tibody precursors that have the potential to evolve into bNAbs.

151 ced Raman scattering (SERS) spectroscopy has evolved into a cross-disciplinary analytical technique b

152 Today the FAST examination has evolved into a more comprehensive study of the abdomen,

153 e cleavage factor, while the paralogous TFS4 evolved into a potent RNA polymerase inhibitor.

154 duct or as a hydroperoxy derivative 7'' that evolved into an electrophilic acyl azolium, opening to t

155 rspective on how this field will continue to evolve is provided.

156 Here we explore evolving issues associated with produced water (PW) mana

157 side the droplets and show that as the torus evolves, its cross-section significantly deviates from c

158 rotein 568 (ZFP568), a member of the rapidly evolving Kruppel-associated box-zinc finger protein (KRA

159 hether they arose independently across newly evolving land plant lineages has long been a matter of d

160 The complicated, evolving landscape of cancer mutations poses a formidabl

161 ceous (201 to 66 Ma), plesiosaurs repeatedly evolved long- and short-necked body plans [1, 2].

162 Social insect colonies have evolved many collectively performed adaptations that red

163 individual components, and many viruses have evolved measures to antagonize or even exploit autophagy

164 theories proposing that the human brain has evolved mechanisms dedicated to control complex social b

165 ic requirements for copper homeostasis, have evolved mechanisms to acquire copper to successfully col

166 Most bacteria have evolved mechanisms to chelate and transport ferric iron

167 interactions and suggest that microbes have evolved mechanisms to modulate sickness-induced behavior

168 as in the catalytic oxidation of water that evolves molecular oxygen.

169 at core components of the cGAS-STING pathway evolved more than 600 million years ago, predating the e

170 or from multiple embryonic cell populations evolving most quickly and into a greater variety of form

171 Organisms have evolved motility organelles that allow them to move to f

172 were too small to allow the reconnection to evolve much beyond the electron scale as recently observ

173 microscopy reveal that rust fungi might have evolved multiple effectors that target chloroplasts or n

174 t has become apparent that the immune system evolved multiple mechanisms for controlling self-reactiv

175 icating that the endosymbiotic lifestyle has evolved multiple times in Chlorellaceae.

176 Herpesviruses have evolved multiple ways to adapt the infected cells to the

177 l genera and illuminates how Sm proteins may evolve new functions.

178 ynamic edges (events) and similarity between evolving node neighborhoods.

179 to suppress immunity; however, the plant can evolve nucleotide-binding domain-leucine-rich repeat dom

180 ure efficient genome duplication, cells have evolved numerous factors that promote unperturbed DNA re

181 selfish genetic elements, bona fide viruses evolved on multiple, independent occasions throughout th

182 haracter evolution describing how viral load evolves on the phylogeny of whole-genome viral sequences

183 bnAbs are therefore expected to evolve only when the B cell lineage evolving breadth is

184 The indicators will also evolve over time through ongoing collaboration with expe

185 is and primary sclerosing cholangitis (PSC), evolve over time with anatomically an ascending course o

186 The mammalian immune system has evolved over many millennia to be best equipped to prote

187 Treatments for alopecia areata (AA) have evolved over the decades from broad and nonspecific ther

188 e valence bias and how this decision process evolves over time.

189 Evolved oxygen is detected by reduction at a Pt UME, all

190 ultiple myeloma is considered a continuously evolving paradigm as a result of the growing availabilit

191 lux analysis were performed on 10 adaptively evolved pgi knockouts of Escherichia coliPgi catalyzes t

192 st in the oxygen-rich chloroplasts of oxygen-evolving photosynthetic organisms.

193 portance of intrinsic constraints imposed by evolved physiological trade-offs versus the proximate ef

194 s a Darwinian process in which B lymphocytes evolve potent antibodies to encountered antigens and gen

195 We find that sociality evolves primarily from host generalists, and almost excl

196 biochemical activity of PBP 2B is perturbed evolved prior to the clinical use of beta-lactams.

197 oundation for spatiotemporal gene expression evolved prior to the divergence of sponges and eumetazoa

198 Mouse models of fully penetrant and slowly evolving prostate tumorigenesis showed that a high calci

199 Starvation arouses evolved protective mechanisms including binge eating and

200 Slowly evolving proteins or sites within proteins were assumed

201 esults suggest that sperm-specific genes can evolve rapidly and that natural genetic variation may ha

202 mmon ancestor of chordates and nematodes and evolved rapidly via duplication.

203 ld of percutaneous coronary intervention has evolved rapidly.

204 ntial function, yet genome defense machinery evolves rapidly.

205 se Genetic testing for breast cancer risk is evolving rapidly, with growing use of multiple-gene pane

206 However, in this work we show that field-evolved resistance to Cry1Fa Bt corn in Puerto Rico is c

207 Reproductive traits in both sexes evolved sensitivity to ecological conditions, as reflect

208 l Skp1 glycosylation pathway in protists and evolved separately from related Golgi-resident GT32 glyc

209 eadlock, due to substitutions in the rapidly evolving Shadow domain.

210 are uncommon, because local brain metabolism evolves significantly with age throughout childhood, lim

211 r clade Archosauromorpha, a group that first evolved some 260 million years ago and is represented to

212 As such, pathogenic bacteria have evolved sophisticated cell surface signaling and transpo

213 Plants have evolved sophisticated mechanisms to adapt to fluctuating

214 y other naturally transformable species, has evolved sophisticated protein machinery for the binding

215 st that the use of a large number of rapidly evolving species-specific proteins represents a common s

216 on and suggests that in eudicots the CYP716s evolved specifically towards triterpenoid biosynthesis.

217 o successfully evade the host, the virus has evolved strategies to counteract antiviral responses, in

218 Organisms have evolved strikingly parallel phenotypes in response to si

219 In rapidly evolving stroke care networks, the question of the need

220 llowing the Catalog to adapt to the needs of evolving study design, genotyping technologies and user

221 ironmental changes on an artificial chemical evolving system outside of computer simulations.

222 We support the conclusion that evolving systems and learning systems are different inst

223 To understand how evolving systems bring forth novel and useful phenotypes

224 Here we evolve the antibiotic resistance protein TEM-1 towards r

225 the first groups originate and subsequently evolve the organizing principles that qualify them as ne

226 We propose that A. oligospora likely evolved the means to use olfactory mimicry to attract it

227 , bats possess the smallest genomes and have evolved the unique abilities of powered flight and laryn

228 the emerging view that cellular systems have evolved the use of pH signals as a means of adapting to

229 eliver information and knowledge are rapidly evolving, there is confidence in the lasting value of me

230 pipelines are in a primitive stage and still evolving; there are many factors that affect expression

231 ganizations, and alternative payment methods evolve, these new systems of care must continue to serve

232 sion hypothesis that suggests xenophilia can evolve through individual selection in social species wh

233 hile the bulk of the protein-coding sequence evolved through a CAG repeat expansion.

234 why so many extracellular domains need to be evolved through natural selection.

235 This process evolves through a [3 + 2] 1,3-DC when cinnamaldehyde is

236 Plants have evolved tightly regulated signaling networks to respond

237 34+ cells, splenomegaly, and a propensity to evolve to acute myeloid leukemia.

238 ised commodity classification systems should evolve to address these gaps.

239 Future research should evolve to define novel methods optimized for the role of

240 tal insights into how molecules interact and evolve to enable the control of reaction chemistry and t

241 Influenza viruses steadily evolve to escape detection by antibodies, necessitating

242 Cancer stem-like cells (CSC) evolve to overcome the pressures of reduced oxygen, nutr

243 e solutions that the human immune system can evolve to recognize a conserved motif buried under a can

244 Our results reveal that ZIKV evolved to acquire a spontaneous mutation in its NS1 pro

245 bipartite or two-signal mechanism has likely evolved to both sustain protective immunity and avoid au

246 nt; thus, unusual enzyme reactions have also evolved to cleave the C-P bond.

247 ecificity, paradigms of cardiac disease have evolved to conceptualize myocardial disease and patient

248 ect cell-to-cell transmission, yet many have evolved to counteract an antiviral protein called tether

249 protein secretion systems have specifically evolved to deliver bacterially encoded proteins into tar

250 e activity of neurons in OFC and MFC rapidly evolved to encode the amount of reward associated with e

251 rchers to identify how migration routes have evolved to exploit predictable atmospheric and oceanic c

252 Cilia have evolved to function as essential sensory organelles in a

253 e whether this distinctive vocal feature has evolved to improve the perception of formants, key acous

254 , a new C-mannosyltransferase has apparently evolved to increase glycosylation of TSRs, potentially t

255 ther, these results show that the shell also evolved to kill parasitic nematodes and this is the only

256 We conclude that synaptic proteins have evolved to limit possible contact site assemblies and mo

257 The biomechanics of animal limbs has evolved to meet the functional demands for movement asso

258 This mechanism evolved to more rapidly produce RPs on demand in differe

259 Proteins have evolved to perform diverse cellular functions, from serv

260 n stages and the molecular preparations they evolved to perpetuate their infectious cycle.

261 A multitude of nanobodies have been evolved to recognize a diverse array of targets, includi

262 These antibodies have evolved to recognize the dense array of glycans that coa

263 We propose importin alpha3 evolved to recognize topologically complex NLSs that lie

264 in the developing vertebrate nervous system evolved to regulate neurogenesis.SIGNIFICANCE STATEMENT

265 e ENaC/degenerin family of ion channels that evolved to respond to extracellular factors.

266 This role in plants may have evolved to restore the growth of embryos after the accum

267 of regulatory mechanisms that bacteria have evolved to sense cellular RSS and mitigate their deleter

268 ise are therefore interdependent and have co-evolved to share an optimal physiological abundance poin

269 hnology and techniques, cataract surgery has evolved to small-incisional surgery with rapid visual re

270 s byproducts of a regulatory mechanism which evolved to support multiple DNA replication forks.

271 at the protein machinery in this process has evolved to take advantage of some set of physical design

272 tness is the extent to which an organism has evolved to withstand the effects of deleterious mutation

273 es in which the length of e ach displacement evolves to show a well-defined characteristic scale that

274 icating that PCA-tdTHz is a quick, powerful, evolving tool for identification and evaluation myelin d

275 that the relative abundance of each segment evolves towards a constant ratio.

276 is important because slow development due to evolved trade-offs can yield phenotypic benefits, wherea

277 an alpha-helix, a 310 helix, and a recently evolved tri-proline loop.

278 the reverse in Carnivora with the braincase evolving twice as fast as the face.

279 ution; it gives ensembles that could further evolve under selection.

280 the specializations of extinct mammals that evolved under strong environmental constraints.

281 With our evolving understanding of intrinsic resistance, people h

282 An evolving understanding of the immunopathogenesis of mult

283 red by a human variable (VH) domain that was evolved using strong selections for enhanced stability a

284 e with environmental stresses, bacteria have evolved various strategies, including the general stress

285 n proposed that pheromone perception in ants evolved via expansions in the numbers of odorant recepto

286 etermining step the resulting loaded complex evolves via an inner-sphere mechanism into a ruthenacycl

287 However, HIV has evolved ways to exploit these cells, facilitating immune

288 phylum are not particularly ancient, having evolved well after the rise of oxygen (ca. 867 million y

289 that lower quality, or more dilute, nectars evolve when the strength of preferring larger quantities

290 oses that these early-emerging social skills evolved when natural selection favored increased in-grou

291 Nonequilibrium emergent states evolve with a complex co-existence of excitons, carriers

292 These boundaries subsequently interact and evolve with the partial dislocations, which migrate from

293 n how mixed selectivity and other properties evolve with training.

294 Options for managing splenic injuries have evolved with a focus on nonoperative management.

295 nator visitation and robbery but may have co-evolved with nectar availability to maintain the fitness

296 esults may suggest that adaptive pathways co-evolved with the expansion of IDDs in the proteome of eu

297 sts that individual behavioural variation co-evolves with life-history variation, causing individuals

298 We also investigated how BAmF evolves with the duration of weight loss.

299 Evolving work reveals that the MBC compartment in mice a

300 data generated by NGS, the presence of newly evolved, yet known, strains of both CPV-2a and CPV-2b we