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1 creting neutron star (NS) with a spin period evolving from 1.43 seconds in 2003 to 1.13 seconds in 20
3 genes indicates that Klosneuviruses did not evolve from a cellular ancestor but rather are derived f
5 By letting this out-of-equilibrium system evolve from a well-defined, but disordered, initial cond
8 in sympatry with other varieties and likely evolved from a bog form on the oldest volcano, Kohala, w
10 monstrated that acute myeloid leukemia (AML) evolved from a chronic phase MPN is distinct from de-nov
11 h representing a large set of sequences that evolved from a common ancestor and that retain conserved
13 iary structures supported that ePKs and ChKs evolved from a common ancestor related to glutaminyl ami
14 This observation also suggests that all NSVs evolved from a common ancestor that has this unique nucl
15 types of mosquito-borne dengue virus (DENV), evolved from a common ancestor, are human pathogens of g
16 alogs--proteins with divergent function that evolved from a common ancestral gene after a duplication
17 Archaeal RNA polymerase (RNAP) and Pol II evolved from a common ancestral structure and the euryar
18 ecialized genes present in today's lifeforms evolved from a common core of ancient, elementary genes.
19 tive mechanism to replace DNA at MAT, likely evolved from a conservative two-locus system that swappe
21 terpene synthase genes in the cluster likely evolved from a diterpene synthase gene in the cluster by
22 he water-oxidizing complex of photosystem II evolved from a former transitional photosystem capable o
24 ree decades, regulatory T cells (Tregs) have evolved from a hypothetical mediator of adoptively trans
25 phylogeny suggests that allotherian mammals evolved from a Late Triassic (approximately 208 million
27 analyses reveal that super-miR7122 may have evolved from a newly defined miR4376 superfamily, which
28 f acute graft-versus-host disease (GVHD) has evolved from a one-size-fits-all approach to a more nuan
30 analysis strongly suggests that bidnaviruses evolved from a parvovirus ancestor from which they inher
32 ibranchial) placodes of vertebrates probably evolved from a posterior proto-placodal region in the tu
33 r of eastern Africa (unlike northern Africa) evolved from a predominantly arid environment with high-
37 H]) magnetic resonance (MR) spectroscopy has evolved from a research tool into a clinical neuroimagin
38 icrobial genome sequencing in particular has evolved from a research tool into an approach that can b
39 ural analyses indicate that MFS transporters evolved from a series of tandem duplications of an ances
40 The isotopic compositions of the total water evolved from a set of natural gypsum samples by DTIA are
41 ggest that contemporary TSF members may have evolved from a short 4-oxalocrotonate tautomerase-like a
42 ng system that has, in the past fifty years, evolved from a simple acoustic based mass sensor to a po
44 Although the mammalian X and Y chromosomes evolved from a single pair of autosomes, they are highly
45 ed that in one voltage duty cycle the plasma evolved from a soft to dissociative ionization source.
46 mbryos upon egg fragmentation and might have evolved from a state of uniform Toll activity associated
47 the system, our thought process, and how it evolved from a tantalizing indication of fluoronium ion
48 -mediated beta-protonation, this process has evolved from a test bed for homoenolate reactivity to a
49 activation genes1/2 (Rag1/2) recombinase has evolved from a transposase gene, demonstrating that TEs
52 Under low tension, the membrane smoothly evolves from a flat to budded morphology as the coat are
53 we are able to show analytically how London evolves from a more loop-like structure, typical of plan
54 no-tectal development and how it dynamically evolves from a nascent and noisy presynaptic neural-scap
56 d to metal centres, and has a structure that evolves from a solvated porous state to a desolvated non
57 ssion of the transcription factor Broad (BR) evolves from a uniform to a two-domain pattern that pref
58 was variable and complex, with relapse often evolving from a clone ancestral to the predominant de no
60 Since its introduction, focal therapy has evolved from ablation of half or three-quarters of the p
62 Subsequently, the synthesized Si nanosheets evolve from amorphous to nanocrystalline to crystalline
63 of anuran amphibians, suggesting that O-MALT evolved from amphibian LAs approximately 250 million yea
64 ence of modern DNA-RNA-protein life, biology evolved from an "RNA world." However, synthesizing RNA a
65 heory proposes that the circadian oscillator evolved from an adaptive temperature sensor: a gene circ
66 e laryngeal component of speech motor output evolved from an already existing, similar network in non
68 history of the AR, because the receptor has evolved from an ancestral 3-ketosteroid receptor through
74 i are closely related genetically; B. mallei evolved from an ancestral strain of B. pseudomallei by g
75 sibilities: that SWEETs and MFS transporters evolved from an ancestral triple-helix bundle or that th
76 ere, we test the hypotheses that bisexuality evolved from an ancestral unisexual condition and is a k
77 in B, ZU5 and Nup98 C-terminal domain likely evolved from an ancient autoproteolytic domain with an H
78 Phylogenetic analysis suggests that CVDE evolved from an ancient de-epoxidase that was present in
79 finding supports the hypothesis that the OCP evolved from an ancient fusion event between genes for t
80 fe Bay, Mars, were derived from sources that evolved from an approximately average martian crustal co
81 an attenuated toxicity bloodstream infection evolved from an asymptomatically carried high-toxicity n
84 rface-enhanced Raman spectroscopy (SERS) has evolved from an esoteric physical phenomenon to a robust
85 studies suggest that this protein might have evolved from an evolutionarily related member of chalcon
86 grossly positive margins; 1 melanoma in situ evolved from an excisionally biopsied moderately dysplas
88 its discovery in 1979, left-handed Z-DNA has evolved from an in vitro curiosity to a challenging DNA
92 These data suggest that the response to DPCP evolves from an inflammatory/effector peak at day 3 to a
93 nigmatic lamellar cuprates, the ground state evolves from an insulator to a superconductor and eventu
94 tory modulations appears adaptive in nature, evolving from an initial lowpass to bandpass modes (with
95 Bacteria with a single cell membrane have evolved from ancestors with two membranes on multiple oc
96 ty, which consist of four types of subunits, evolved from ancestral complexes of two types of subunit
97 evidence for the theory that speech may have evolved from ancestral primate rhythmic facial expressio
98 verse enzymatic functions and reactions have evolved from ancestral scaffolds is fundamental to under
99 are structurally related and likely to have evolved from ancestral voltage-gated sodium channels tha
102 etrics are measured and compared as the FETs evolve from back-gated, to top-gated and finally, to str
104 the hPSC field, genome editing in hPSCs has evolved from being a daunting task a few years ago to a
105 ast two decades, organotrifluoroborates have evolved from being chemical curiosities to important rea
107 ways the field has come full circle, having evolved from being driven almost exclusively by our know
108 y shows that marine planktonic cyanobacteria evolved from benthic marine and some diverged from fresh
109 he gymnosperm-specific TPS-d3 subfamily that evolved from bifunctional diTPS rather than monofunction
110 major human pathogens may have independently evolved from bird endoparasites that formerly infected t
111 re due to the application of uniaxial stress evolves from brittle cracking to system-spanning diffuse
112 In the past 9 years, the substrate scope has evolved from bulky polar species to include a wide range
113 fossorial adaptation, suggesting that snakes evolved from burrowing rather than marine ancestors.
114 ulations show that (amino)(carboxy) radicals evolve from C-centered radical to ambidentate C,O-radica
116 ambitious endeavor; however, the C4 pathway evolved from C3 on multiple independent occasions over t
117 In this study, we report a DNA aptamer probe evolved from cell-SELEX that can recognize thrombospondi
118 n alga Spirogyra pratensis Since land plants evolved from charophytes, this implies conservation of e
120 Surgical treatment of fecal incontinence has evolved from colostomy and direct repair of muscle defec
121 brate phyla as well as in chordata, and rods evolved from cones, but the sequence of events is not we
122 ions are being made, how collective behavior evolves from daily to decadal time scales, and how this
124 standing of the genetic basis of disease has evolved from descriptions of overall heritability or fam
125 sification of hematological malignancies has evolved from descriptive approaches, based on either cyt
126 arene bidentate urea, voltammetric responses evolve from diffusion-controlled waves (where the bindin
127 ively increases relative to the cargo speed, evolving from diffusion to pole-to-pole oscillation, loc
128 n Caenorhabditis elegans, is thought to have evolved from dioecy (males/females) through a trioecious
131 se results suggest that Cry1 and Cry2, which evolved from DNA repair enzymes, protect genomic integri
132 esistant cancer cells can both pre-exist and evolve from drug-tolerant cells, and they point to thera
133 iology of the resistant clone, as those that evolved from drug-tolerant cells had a diminished apopto
137 ; in other words, we prove that the contours evolving from either of these systems cannot intersect a
143 ch into antidepressant therapies for TRD has evolved from explorations of antidepressants with primar
144 We speculate that this connectivity scheme evolved from exposure to natural vibrations containing o
150 tigators generally agree that color lexicons evolve from fewer terms to more terms, as technology adv
151 rsus [substrate] show a rate dependence that evolves from first-order at low concentration to zero-or
152 day mitochondria and plastids (chloroplasts) evolved from formerly free-living bacteria that were acq
154 Phylogenetic analysis suggests that LGC-35 evolved from GABA-A receptors, but the pore-forming doma
155 phylogenetic analysis showing that GPV-QH15 evolved from goose lineage parvoviruses, rather than fro
157 nge of basal demosponges that appear to have evolved from hexactine-bearing reticulosan ancestors, al
158 itive allosteric modulator (PAM), chemically evolved from hits identified through a M4 allosteric fun
159 l nicotinic acetylcholine receptors (nAChRs) evolved from homomeric nAChRs in which all five subunits
160 nset and female preponderance appear to have evolved from human interactions with pathogens in the mi
161 question of mapping sequence to function has evolved from identifying functional elements to characte
163 d that antibiotic stewardship models need to evolve from infection specialist-based teams to develop
164 time that the direction tuning of MT neurons evolved from initially representing the vector-averaged
165 chronic hepatitis C virus (HCV) infection is evolving from interferon (IFN)-based therapy to direct-a
167 encodes a RWP-RK domain transcription factor-evolved from its ancestral role in C. reinhardtii as a m
170 laterians [5, 6], (2) that interstitial taxa evolved from larger ancestors by miniaturization, or (3)
171 hat enzymes with strict functionalities have evolved from less specific ancestors through a small num
175 he conformational epitope recognition, which evolved from low to high conformations in the natural ho
176 Contrary to the hypothesis that odontocetes evolved from low-frequency specialists [4], we find evid
177 ate that > 2000 and > 500 species could have evolved from low-latitude N-fixing trees and high-latitu
181 hough freshwater stickleback have repeatedly evolved from marine populations, we show that freshwater
183 that mechanisms of memory and planning have evolved from mechanisms of navigation in the physical wo
184 zyme, and it has been postulated that it has evolved from members of the phosphotriesterase-like lact
186 s with increasing O-content, as active sites evolve from metal atom pairs (*-*) to oxygen atom (O*-O*
187 se by screening candidate enzymes previously evolved from Methanococcus janaschii Tyr synthetase for
188 ransition to herbivory because they recently evolved from microbe-feeding ancestors and are closely r
190 duce recombinant vaccines in plant cells has evolved from modest proofs of the concept to viable tech
196 ontrast to other pediatric cancers, does not evolve from neuroblasts that continue to divide and invo
197 eral, and demonstrate that large species may evolve from neutral macroevolutionary diffusion processe
198 sis, Phosphoenolpyruvate Carboxylase (PEPC), evolved from nonphotosynthetic PEPC found in C3 ancestor
201 ents of its human host as the disease course evolves from one of asymptomatic nasopharyngeal carriage
202 omputing Fermi contacts, which by design had evolved from optimization of a collection of inexpensive
203 tem known: the mammalian X and Y chromosomes evolved from ordinary autosomes beginning at least 180 m
208 t some free-living bacterioplankton lineages evolved from patch-associated ancestors up to several hu
209 f outbreak identification and resolution has evolved from phenotypic analysis, such as serology and b
210 epressors cryptochrome 1 (Cry1) and 2 (Cry2) evolved from photolyases, bacterial light-activated DNA
211 ms change shape as the mass transport regime evolves from planar diffusion at short times to hemisphe
213 center (GC), where humoral immune responses evolve from potentially oncogenic cycles of mutation, pr
214 a slowly developing malignancy postulated to evolve from premalignant lesions in chronically damaged
217 en established that ubiquitin-like modifiers evolved from prokaryotic sulphur transfer proteins it is
218 oposal that modern 1,10-synthases could have evolved from promiscuous 1,11-sesquiterpene synthases.
219 via a thermodynamically driven charge shift evolving from PTZP-Pc1(*+)-C60A(*-) and exhibits lifetim
220 of the non-interacting lattice component can evolve from quasi-3D to quasi-1D, leading to strong Ferm
221 ary algorithm, with which VP and AAP were co-evolved from random or native nucleotide sequences in si
222 ary arteriovenous malformations (PAVMs) have evolved from rare curiosities to not uncommon clinical s
223 e possibility for Tehuacan maize cultivation evolving from reduced founder populations of isolated an
224 EDSS >/= 6, and 18.1% (95% CI = 13.5-22.5%) evolved from relapsing MS to secondary progressive MS (S
227 analysis suggested that SbCYP82D2 might have evolved from SbCYP82D1.1 via gene duplication followed b
228 r assessing prognosis in uveal melanoma have evolved from simple physical features, such as tumor siz
229 regulation of gene expression in mammals has evolved from simpler eukaryotic systems, yet the mechani
233 w these features developed as tyrannosaurids evolved from smaller basal tyrannosauroids that first ap
234 ategies to reduce human schistosomiasis have evolved from 'snail picking' campaigns, a century ago, t
236 d where volumes with nearly perfect lattices evolve from structures filled with dislocations, and how
237 life was thermophilic and that proteins can evolve from substrate-promiscuous generalists into speci
238 wever, it is not clear whether the pathogens evolved from symbionts or symbionts from pathogens.
239 tamers are short DNA or RNA oligonucleotides evolved from systematic evolution of ligands by exponent
241 ecades, our understanding of eosinophils has evolved from that of categorically destructive effector
242 ularly pancreatic ductal adenocarcinoma, has evolved from that of host defense to tumor offense.
244 decisions at multiple scales of abstraction evolve from the dynamics of preceding brain activity.
245 ic models that show how accretionary margins evolve from the initial collision, through a period of p
246 enotypic activity and evolutionary potential evolve from the two pathways, as well as from replicate
250 r chloroplast outer membrane (COM) proteins, evolved from the ankyrin repeat domain (ARD) of the host
251 uctance regulator (CFTR) is an anion channel evolved from the ATP-binding cassette (ABC) transporter
252 rm and mesoderm in triploblastic bilaterians evolved from the bifunctional endomesoderm (gastrodermis
253 , the parameters describing how our universe evolved from the Big Bang are generally known to a few p
254 our understanding of these diseases has now evolved from the concept of a primary inflammatory condi
255 shear conditions using an adhesive disc that evolved from the dorsal fin spines typical of other fish
258 abatic quantum computing, a system is slowly evolved from the ground state of a simple initial Hamilt
259 Reperfusion therapy for acute stroke has evolved from the initial use of intravenous tissue plasm
260 ition, because MEMS manufacturing techniques evolved from the microelectronic industry, FMDs can be m
263 We suggest that the Ca(2+)-binding mechanism evolved from the more ancient phosphorylation-based syst
264 onary rate estimation indicate that VT-AANAT evolved from the nonvertebrate form of AANAT after the C
265 ings explain how the outer segment structure evolved from the primary cilium to provide photoreceptor
270 in, we report a series of miniprotein hosts, evolved from the tenth type III domain of fibronectin (F
273 drostatic pressure, the magnetic state of Eu evolves from the canted antiferromagnetic structure in t
274 or, the most common pediatric kidney cancer, evolves from the failure of terminal differentiation of
275 ing organism, PCa's epigenome is plastic and evolves from the pre-neoplastic to the metastatic stage.
276 xtures demonstrate that the good performance evolves from the synergistic hierarchical structure.
277 otential when the magnetisation of the disks evolves from the vortex-like state to an onion-like one
278 nd cancer cells are continuous, dynamic, and evolving from the initial establishment of a cancer cell
279 n, the thermodynamic properties of solutions evolving from the non-sink dissolution of amorphous soli
280 Treatment for non-small-cell lung cancer is evolving from the use of cytotoxic chemotherapy to perso
282 inhibitor of apoptosis (IAP) proteins likely evolved from their host cell IAP homologs, which functio
283 ve, while polyaromatic foldamers have barely evolved from their nascency and remain perplexing for me
285 f specialised sensory receptors and neurons, evolved from these domains only in the vertebrate lineag
287 r traits, large cross-trait maternal effects evolve from those maternal traits that experience the sm
289 y systems for detecting tactile stimuli have evolved from touch-sensing nerves in invertebrates to co
292 the ubiquitous NRT1/PTR FAMILY (NPF) likely evolved from transporters of the ancestral cyanogenic gl
293 investigate how recognition of EF-P by PoxA evolved from tRNA recognition by aminoacyl-tRNA syntheta
294 ionary basis to believe that conscious goals evolved from unconscious and selfish forms of pursuit.
297 These compact binaries are believed to have evolved from wider orbits into their current configurati
298 adapted and host-restricted bacterial clades evolve from within a broader host-promiscuous species an
299 ong genomic evidence indicating that turtles evolved from within the diapsid radiation (which include
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