ライフサイエンスコーパス: excess risk

1 ith warfarin, thus showing no benefit and an excess risk.

2 delivery or a low birth weight delivery, to excess risk.

3 sed a random-effects model to derive overall excess risk.

4 ch contributing approximately equal absolute excess risk.

5 medications could partially account for this excess risk.

6 iated tissues without clinically significant excess risk.

7 ics explained approximately one fifth of the excess risk.

8 t therapy to raise renin might mitigate this excess risk.

9 re modifications to the relative or absolute excess risk.

10 isks were used to quantify cardiac mortality excess risk.

11 renin (>/=1 mug/L per h) had no significant excess risk.

12 mmon, but seemed to involve similar absolute excess risks.

13 eplacement should be provided to limit these excess risks.

14 ternal causes; and 0.05 for death from other excess risks.

15 ular emissions with all cardiovascular EDVs (excess risk = 1.6%, 95% confidence interval: 0.9, 2.4 fo

16 mong head and neck tumor survivors (absolute excess risks =30 versus 11).

17 erated the highest risk estimate for asthma (excess risk = 4.5%, 95% confidence interval: 1.1, 8.0).

18 3.64; 95% CI, 1.34 to 7.93; P=0.02; absolute excess risk, 6.21 cases per 1 million person-years) and

19 absolute excess risks than females (absolute excess risks =7 versus 3), especially among head and nec

20 2.62; 95% CI, 1.26 to 4.82; P=0.02; absolute excess risk, 8.82 cases per 1 million person-years), wit

21 spitalization rate ratios (RRs) and absolute excess risks (AERs) were calculated.

22 andardized incidence ratios (SIRs), absolute excess risks (AERs), and cumulative incidence of subsequ

23 mortality ratios (SMRs) for CVD and absolute excess risks (AERs; number of excess deaths per 10,000 p

24 only 1 of these exposures have little or no excess risk after controlling for conventional risk fact

25 ions, and behaviors) explained over half the excess risk among African Americans and Hispanic/Spanish

26 ESRD exemplified by the three- to four-fold excess risk among black compared with white individuals

27 d to be scaled up or modified to address the excess risk among blacks.

28 cond study (mid-year 2010), the proportional excess risk among smokers (RR-1) approximately doubled o

29 art failure occurs in older individuals, the excess risk and risk factors for heart failure in indivi

30 Early diagnosis and treatment decrease the excess risk, and strategies for identification of affect

31 Standardized mortality ratios, absolute excess risks, and cumulative risks were calculated.

32 This excess risk appeared entirely among those with coinfecti

33 The types of malignancies observed at excess risk are similar to those observed in solid organ

34 association and strategies to mitigate this excess risk are warranted.

35 Much of this calculated excess risk arises from exposures to PAHs in early child

36 has not changed significantly, there may be excess risk associated with combined angiogenesis blocka

37 The excess risk associated with lower CC16 concentrations is

38 ish childhood cancer survivors, the greatest excess risk associated with subsequent primary neoplasms

39 ith nondiabetic patients, there were similar excess risks associated with ITDM/NITDM in patients sele

40 Excess risks attenuated over time and were generally no

41 y, age, or stroke severity, but the absolute excess risk attributable to alteplase was bigger among p

42 The proportion of excess risk attributable to the interaction of high CRP

43 ct was modified by smoking behavior, with no excess risk being observed in never smokers.

44 and does not expose patients to significant excess risk, but requires timely communication between c

45 This represented an 11% excess risk compared to the reference population, mainly

46 The excess risk conferred by carriage of the combination of

47 ions in African Americans might reduce their excess risk deserves further study.

48 and cumulative SHS exposures, with relative excess risk due interaction for parental asthma and over

49 3.44-46.91) for their joint effect (relative excess risk due interaction, 9.08 [-0.22 to 43.18]).

50 RR] during drug exposure vs nonexposure) and excess risk due to concomitant drug exposure (relative e

51 Rose and van der Laan criticize the relative excess risk due to interaction (RERI) measure, the use o

52 the highest risk of COWO [RR>/=2.0, relative excess risk due to interaction (RERI) not significant].

53 obesity (BMI >/=30) and calculated relative excess risk due to interaction (RERI) on an additive sca

54 The relative excess risk due to interaction (RERI) provides a useful

55 e interaction was assessed with the relative excess risk due to interaction (RERI).

56 ntified a statistically significant relative excess risk due to interaction (uncorrected P = 4.51 x 1

57 rate lifetime drinking and binging (relative excess risk due to interaction = 0.33, 95% CI: 0.10, 0.5

58 5% confidence interval: 1.74, 6.01; relative excess risk due to interaction = 2.15, 95% confidence in

59 k due to concomitant drug exposure (relative excess risk due to interaction [RERI]).

60 We estimated the relative excess risk due to interaction and its 95% confidence in

61 There was no evidence of synergism (i.e., excess risk due to interaction) between malaria infectio

62 their effects on food allergy risk (relative excess risk due to interaction, 15.11; 95% CI, 4.19-35.3

63 interactions on both the additive (relative excess risk due to interaction, 5.06; 95% CI, 1.33-11.04

64 Relative excess risk due to interaction, attributable proportion

65 dichotomous exposures, such as the relative excess risk due to interaction, using case-control data

66 ivity was assessed by estimating the reduced excess risk due to interaction.

67 raction effect, referred to as the "relative excess risk due to interaction." In this article, we rei

68 ross defects, were constructed, and relative excess risks due to interaction were calculated.

69 Relative excess risks due to interaction, attributable proportion

70 Although this excess risk during therapy is likely due to multiple fac

71 analysis was then applied to estimate pooled excess risks (ER).

72 Hospital excess risk estimates range from -1.4% to 2.0% across me

73 igarette smoking and smaller but significant excess risks even at the much lower exposure levels asso

74 508.97 [95% CI, 474.16-545.66]) and a 2-fold excess risk for 10 to 15 years thereafter (SIR, 2.22 [95

75 Diabetes confers about a two-fold excess risk for a wide range of vascular diseases, indep

76 iovascular events, statistically significant excess risk for ACVD was reported in individuals with pe

77 The excess risk for all-cause dementia observed for individu

78 The excess risk for all-cause mortality decreases to the lev

79 Our novel observations of an excess risk for AML/MDS following IgG/IgA (but not IgM)

80 rticularly men who have sex with men, are at excess risk for anal cancer, it has been difficult to di

81 ny of 3 questions: What is the incidence and excess risk for breast cancer in women after chest radia

82 Compared with essential hypertension, the excess risk for cardiovascular events and mortality was

83 The estimated absolute excess risk for CHD for women within 10 years of menopau

84 nsitive to treatment effectiveness, absolute excess risk for CHF, and asymptomatic left ventricular d

85 However, the excess risk for CP among these infants is unknown.

86 th lower degrees of TSB level elevation, the excess risk for CP is minimal.

87 The excess risk for diabetes was practically absent in those

88 SD (but not trauma only) was associated with excess risk for drug abuse or dependence (adjusted relat

89 Some studies of brain cancer have found an excess risk for farmers.

90 This excess risk for female workers persisted when injuries w

91 calculate adjusted relative risks (aRRs) and excess risk for fever on days 0 to 1, adjusted for age g

92 Excess risk for hemorrhagic stroke and gastrointestinal

93 served significant (p </= 0.01) dose-related excess risk for male breast cancer incidence and mortali

94 Excess risk for nonfatal hemorrhagic stroke appeared con

95 d Trade Center Health Registry, there was an excess risk for prostate cancer, thyroid cancer, and mye

96 d standardised incidence ratios and absolute excess risk for subsequent neoplasms with age-specific,

97 n fertilizer use and water arsenic (relative excess risk for the interaction = 0.06, 95% confidence i

98 east cancer, increase with age; however, the excess risk for these conditions that can be attributed

99 Determining those at excess risk for transplant is critical to these imperati

100 h standardized mortality ratios and absolute excess risks for ischemic heart disease, valvular heart

101 The excess risks for lung and urinary tract cancers were hig

102 for female breast cancer, although absolute excess risks for males are much less than for females.

103 The relative excess risks for the interactions between smoking status

104 Excess risk from concomitant use of nsNSAIDs with select

105 ed with BMS may counterbalance the potential excess risk from late ST with drug-eluting stents.

106 uting stents might offset some or all of the excess risk from ST.

107 CD have an increased NHL risk; however, the excess risk has tapered off substantially in the last 4

108 hase (mean follow-up, 22 years) did not have excess risk (HR, 1.02; 95% CI, 0.72-1.44) but those with

109 The excess risk in blacks compared with whites (age-adjusted

110 one system (RAAS) inhibition does not confer excess risk in heart failure patients with reduced eject

111 risk factors for AIDS mortality, whereas the excess risk in MSM was unchanged.

112 There was no indication of an excess risk in persons younger than 50 years.

113 tal morbidity, there was weak evidence of an excess risk in women taking tricyclic antidepressants, a

114 Recent studies have reported excess risk in workers who are occupationally exposed to

115 population, varied greatly, from substantial excess risks in large patient groups to lower risks of d

116 artan treatment in HFpEF was associated with excess risk, in contrast to WRF occurring with RAAS bloc

117 lence of periodontitis, even low to moderate excess risk is important from a public health perspectiv

118 eases with increasing BMI and the associated excess risk is much greater after surgery than without s

119 sociation of ADEM with Tdap vaccine, but the excess risk is not likely to be more than 1.16 cases of

120 This excess risk is similar regardless of ejection fraction b

121 jointly accounted for approximately half the excess risk linked with maternal psychiatric inpatient h

122 However, this excess risk may be attributable to tobacco smoking rathe

123 We sought to determine whether any of this excess risk may be explained by vitamin D status, which

124 However, the percentage of excess risk mediated (PERM) by these proximate causes of

125 We calculated the percentage of excess risk mediated by risk factors to assess the exten

126 lic abnormalities did not confer substantial excess risk, not even for severe or long-lasting obesity

127 s 22.9 (95% CI, 14.2 to 35) with an absolute excess risk of 93.7 cases per 10,000 person-years.

128 who received >or= 270 mg/m(2) had a 4.5-fold excess risk of abnormal NICT (95% CI, 2.1 to 9.6) compar

129 exposure of the heart to radiation to avoid excess risk of ACEs after radiotherapy for BC.

130 Conclusion The excess risk of acute myeloid leukemia and/or myelodyspla

131 tertile was associated with an even greater excess risk of advanced fibrosis than advanced inflammat

132 and hospital admission during follow-up, the excess risk of AIDS-related death decreased for heterose

133 erial administration was not associated with excess risk of AKI acute kidney injury , dialysis, or de

134 In SEER 9, there was a significant excess risk of all types of second cancers combined (SIR

135 h type 1 diabetes have a roughly 40% greater excess risk of all-cause mortality, and twice the excess

136 Recently, an excess risk of AML/MDS was found among 5652 patients wit

137 compared with the general population had an excess risk of anal cancer, with SIRs of 109.8 (95% CI,

138 The excess risk of antibiotic use and hospital-treated infec

139 ssel and cardioembolic subtypes, they had no excess risk of asymptomatic carotid disease (adjusted OR

140 The excess risk of atrial fibrillation in individuals with t

141 Among individuals with normoalbuminuria, no excess risk of atrial fibrillation was noted in men with

142 rofound B-cell deficiency associated with an excess risk of bacterial infection and higher mortality.

143 ds assessed at YAT0) signaled a 2- to 3-fold excess risk of being drug-dependent (adjusted prevalence

144 Absolute excess risk of biliary tract disease associated with ADP

145 ducation received also seemed to explain the excess risk of black race in the discrepant group that r

146 was heterogeneity with one study showing an excess risk of campylobacteriosis.

147 pients should balance the harms, such as the excess risk of cancer against the survival gains and qua

148 risk factors, we converted absorbed doses to excess risk of cancer incidence and used them to directl

149 ll, survivors have a clear radiation-related excess risk of cancer, and people exposed as children ha

150 on analysis of SIRs was used to estimate the excess risk of cardiac interventions from mediastinal ir

151 s has been shown to unequivocally reduce the excess risk of cardiovascular complications.

152 ents with chronic kidney disease, experience excess risk of cardiovascular disease and elevated total

153 Excess risk of cardiovascular disease occurs in effectiv

154 Diabetes confers a two times excess risk of cardiovascular disease, yet predicting in

155 th systemic lupus erythematosus (SLE) are at excess risk of cardiovascular events (CVEs).

156 HIV-infected adults have excess risk of cardiovascular, liver, kidney, bone, and

157 The excess risk of cerebral infarction among CNS tumor survi

158 approximately 0.08 U) associated with a 48% excess risk of CHD (odds ratio [OR] for CHD, 1.48; 95% c

159 ational studies suggest an approximately 40% excess risk of CHD in employees working long hours.

160 Excess risk of concomitant use of nsNSAIDs with anticoag

161 Whether smoking confers the same excess risk of coronary heart disease for women as it do

162 The excess risk of CVD associated with active smoking was ex

163 An excess risk of CVD occurs early in the RA disease course

164 was significantly associated with increased excess risk of death (RER 1.48, 95% CI 1.31-1.68, p-valu

165 y-based observational study to determine the excess risk of death according to the level of glycemic

166 hing by insurance explained one third of the excess risk of death among nonelderly black versus white

167 Long-term trends in excess risk of death and cardiovascular outcomes have no

168 The excess risk of death associated with a high BMI, however

169 HR: 0.96; 95% CI: 0.58 to 1.53), whereas the excess risk of death associated with HG aortic stenosis

170 Our study found an excess risk of death due to both liver-specific and non-

171 The excess risk of death from any cause and of death from ca

172 The excess risk of death from ischemic, but not hemorrhagic,

173 stics matching accounted for the 54% and 27% excess risk of death in black patients, respectively.

174 rs combined accounted for 76.3% of the total excess risk of death in black patients; insurance accoun

175 The excess risk of death in black versus white men diagnosed

176 In those age >/= 65 years, the excess risk of death in blacks versus whites was nonsign

177 aprotinin was found to be associated with an excess risk of death of 1.59 per 100 patients (95% CI, 0

178 pared to matched controls, and over half the excess risk of death was due to seemingly unrelated co-m

179 Atrial fibrillation carries an excess risk of death, which is the highest for AF develo

180 rated that statin therapy is associated with excess risk of developing diabetes mellitus.

181 abetes during 2006 and 2007, we measured the excess risk of developing diabetes triggered by undernou

182 rol alone was associated with a 2- to 3-fold excess risk of developing drug dependence (adjusted rela

183 ) up to the age of 4 years are at a 150-fold excess risk of developing myeloid leukemia (ML-DS).

184 tients with metabolic syndrome were at a 21% excess risk of developing subclinical hypothyroidism (ad

185 Survivors of childhood cancer are at excess risk of developing subsequent primary neoplasms b

186 rum potassium appeared to explain 18% of the excess risk of diabetes in African Americans, which is c

187 that low serum potassium contributes to the excess risk of diabetes in African Americans.

188 We found a massive excess risk of diabetes in people born during the times

189 eded statin therapy may be withheld to avoid excess risk of diabetes while representing the strongest

190 In contrast, a modest excess risk of disability was observed in African Caribb

191 An excess risk of DLBCL and FL was found in Q fever patient

192 The excess risk of each cause of death in the 5 years subseq

193 a BMI of 22.6 to 25.0, whereas there was no excess risk of either death from any cause or cause-spec

194 ng kidney donation may be associated with an excess risk of end-stage kidney disease and death.

195 These new data demonstrate that much of the excess risk of ESRD in African American individuals is a

196 and accounted for a large proportion of the excess risk of ESRD observed in African compared to Euro

197 isk susceptibility genes explain <40% of the excess risk of familial ovarian cancer.

198 s risk of all-cause mortality, and twice the excess risk of fatal and nonfatal vascular events, compa

199 The excess risk of fever after TIV and PCV13 was 20 and 23 p

200 ior exposure in utero was associated with an excess risk of food sensitization at age 4 years (OR 1.4

201 There was an excess risk of genitourinary tract cancers among recipie

202 ll results suggest that there may be a small excess risk of HCC in individuals with GSTT1 null and po

203 ndom-effects meta-analyses suggested a small excess risk of HCC with GSTT1 null (odds ratio (OR) = 1.

204 nge (> or =30 kg/m(2)) is associated with an excess risk of heart failure (HF).

205 We aimed to determine the excess risk of heart failure in individuals with type 1

206 f the cytokine network may contribute to the excess risk of heart failure in these patients.

207 This excess risk of hemorrhagic stroke is particularly high i

208 The excess risk of hepatoblastoma was associated with low bi

209 diographic evaluation are associated with an excess risk of HF and may predict post-LTx survival.

210 The excess risk of HF associated with CKD was particularly l

211 mediate variables that explained the highest excess risk of IHD from genetically determined obesity w

212 ure with 7%, and remnant cholesterol with 7% excess risk of IHD.

213 The excess risk of incident heart failure in black women is

214 a than are their non-pregnant peers, and the excess risk of infection varies with gravidity.

215 The relative excess risk of interaction was -0.34 (95% CI: -0.60, -0.

216 r baseline stroke severity, but the absolute excess risk of intracerebral haemorrhage increased with

217 e benefits of RV5 and RV1 outweigh the small excess risk of intussusception.

218 dent colorectal cancer, but we did see a 19% excess risk of invasive breast cancer among those with A

219 The HRs indicate excess risk of ischemic stroke was apparent in all categ

220 We aimed to assess the excess risk of leukaemia and brain tumours after CT scan

221 Coinfection with S. mekongi resulted in excess risk of liver fibrosis and left liver lobe enlarg

222 imate the age-specific risk of infection and excess risk of LTBI from household and community exposur

223 Estimates of the relative excess risk of lung cancer mortality due to interaction,

224 The excess risk of lymphoma attributed to psoriasis was 7.9/

225 = .03) were independently associated with an excess risk of MGUS.

226 with DM between 1998 and 2010; however, the excess risk of MI incidence remains 3 to 4x greater in p

227 Despite the excess risk of mortality in young women (</=55 years of

228 It has been hypothesized that the observed excess risk of multiple myeloma (MM) among obese persons

229 herbicides, fungicides) are associated with excess risk of multiple myeloma and its precursor state,

230 Pesticides are associated with excess risk of multiple myeloma, albeit inconclusively.

231 ity and black race have been associated with excess risk of multiple myeloma.

232 The excess risk of myopathy was only two per 10,000 patients

233 Similar to cardiac disease, the excess risk of noncardiac vascular disease in RA is like

234 An excess risk of nonmelanoma skin cancer was observed subs

235 No excess risk of other vascular and nonvascular outcomes w

236 D status may explain nearly one-third of the excess risk of PAD in black compared with white adults.

237 alkylating chemotherapy carries little to no excess risk of POF.

238 Hospital-based series indicate an excess risk of progression from MBL to chronic lymphocyt

239 height with poor GWG was associated with an excess risk of SGA birth, while high GWG combined with e

240 The adjusted excess risk of SIEs in nonbreastfed infants was large be

241 The excess risk of small airway disease in female mice after

242 x and oropharynx cancers carried the highest excess risk of SPM.

243 t trimester of pregnancy would mark women at excess risk of spontaneous preterm birth (sPTB) and exam

244 The excess risk of stroke associated with diabetes is signif

245 The excess risk of stroke attributable to psoriasis in patie

246 Whether and to what extent the excess risk of stroke conferred by diabetes differs betw

247 erapy in both study groups and estimated the excess risk of stroke death associated with nonadherence

248 The excess risk of stroke remained unchanged in analyses tha

249 The relative excess risk of T2DM was 4.78 for individuals who smoked

250 These results indicate that any excess risk of these cancers, even from relatively high

251 The excess risk of TIMI major bleeding with ENOX versus UFH

252 s, statin therapy is associated with a small excess risk of transaminase elevations, but not of myalg

253 in African Americans may contribute to their excess risk of type 2 diabetes relative to whites.

254 ists, or anticoagulants produces significant excess risk of UGIB.

255 Most of the excess risk of vascular mortality due to smoking in wome

256 However, because the excess risk of venous thromboembolic events (VTEs) with

257 The threshold excess risk of very late DES thrombosis compared with BM

258 Significant excess risks of both outcomes were observed in obese wom

259 Specifically, we observed significant excess risks of cancers of the endometrium (n = 11; obse

260 tandard incidence ratios (SIRs) and absolute excess risks of cardiac procedures compared with a norma

261 95% CI: 1.0, 1.4) were associated with small excess risks of cardiovascular disease; periodontal dise

262 The excess risks of death from any cause and cardiovascular

263 The excess risks of death from any cause and death from card

264 ne third of all deaths; the largest absolute excess risks of death were from renal disease (rate rati

265 There was no evidence of excess risks of hepatitis (21 [0.5%] vs 18 [0.4%]), gall

266 .29-3.13) were both associated with moderate excess risks of later ASDs, whereas the HR for later ASD

267 There were significant excess risks of major coronary event (2.44, 95% CI 2.18-

268 The excess risks of mental, physical, and social health outc

269 ight indicate an association with HPV, while excess risks of other cancers could point to differences

270 No reported excess risks of pneumonia (5% in the placebo group, 6% i

271 We calculated a risk difference (excess risk) of TM and ADEM for each vaccine.

272 Results for GSTP1 A313G suggested no excess risk (OR = 0.75, 95% CI: 0.50, 1.15).

273 The absolute excess risk per 1,000 patients per year was 1.67 for CVA

274 a visits showed associations (for 2-day lag, excess risk per 10 mug/m(3) = 3.3%, 95% confidence inter

275 d hospitalization ratios (SHRs) and absolute excess risks per 10 000 person-years.

276 -MOST intracerebral haemorrhage the absolute excess risk ranged from 1.5% (0.8-2.6%) for strokes with

277 onsiderable mortality during adulthood, with excess risks reducing life expectancy by as much as 28%.

278 For head and neck tumor survivors, this excess risk remains high across all ages.

279 extent (12.8) and also produced the greatest excess risk (RERI, 5.5).

280 younger age at diagnosis was associated with excess risk specifically from radiation therapy compared

281 US hospitals receive financial penalties for excess risk-standardized 30-day readmissions and mortali

282 peratures, increasing risk temperatures, and excess risk temperatures were statistically identified t

283 Males had significantly higher absolute excess risks than females (absolute excess risks =7 vers

284 Corresponding observational excess risks using conventional body mass index were 21%

285 Excess risk varied by cancer type (greatest for lung), c

286 However, the excess risk varied markedly by type of birth defect.

287 The amount of the adjusted excess risk varies by type of cardiovascular outcome and

288 as 0.93 (95% CI, 0.65-1.33) and the absolute excess risk was -2 per 10,000 person-years; 60 to 69 yea

289 [CI], 1.2-471.6; P = .04), and the estimated excess risk was 0.385 (95% CI, -.04 to 1.16) cases per m

290 The maximum absolute excess risk was at attained ages 50 to 59 years.

291 This excess risk was much smaller than that observed during t

292 for VTE the first year after discharge, the excess risk was not greater in patients with RA than in

293 A pattern of excess risk was noted in UNHCR-managed camp data where t

294 No excess risk was observed for breast cancer in premenopau

295 s adjusted for sociodemographic factors; the excess risk was unchanged after adjustment for cognitive

296 Absolute excess risks were 18.2, 19.3, 9.4, 14.1, and 4.7 per 10

297 Absolute excess risks were calculated by subtracting cause-specif

298 Standardized mortality ratios and absolute excess risks were used to quantify cardiac mortality exc

299 The pattern of excess risk with a maximum BMI above normal weight was m

300 estimators generally trended toward a small excess risk with publication of more recent studies.