ライフサイエンスコーパス: excise

1 cone depth or proportion of cervical length excised.

2 e RNA and forming an intron lariat, which is excised.

3 he guanosine nucleoside that is subsequently excised.

4 CI: 96.4%, 100%) targets and reflectors were excised.

5 these 80 surgical procedures, 147 SLNs were excised.

6 ins freezing tissues in situ before they are excised.

7 minant role of UvrD in vivo is to unwind the excised 13-mer from dsDNA and that mutation of uvrD resu

8 ctonically juxtaposed along a structure that excised 25 km of crust.

9 Twenty-three lesions were excised (3 nevi, 10 melanomas, 5 squamous cell carcinoma

10 Here, we describe how AlkC selects for and excises 3mA using a non-base-flipping strategy distinct

11 In DNA demethylation, TDG excises 5-formylcytosine (fC) and 5-carboxylcytosine (ca

12 Essential for DNA demethylation, TDG excises 5-formylcytosine and 5-carboxylcytosine, derivat

13 deamination of 5-methylcytosine (mC), and it excises 5-formylcytosine and 5-carboxylcytosine, oxidize

14 Formamidopyrimidine-DNA glycosylase (Fpg) excises 8-oxoguanine (oxoG) from DNA but ignores normal

15 Although these mutants excise a single nucleotide at a normal rate, they lack p

16 6, and TPB7 Here, we show that TPB1 and TPB6 excise a small, distinct set of 12 unusual IESs that dis

17 5'-dsDNA exonuclease activity that precisely excises a dinucleotide using an intrinsic 'tape-measure'

18 into a functional higher-order complex that excises a unit length genome from a concatemeric DNA pre

19 roposed that UNG could cooperate with MMR by excising a second uracil in the vicinity of the U:G mism

20 y, and showed this activity is important for excising abasic site damage from ends.

21 es protect genomic integrity by locating and excising aberrant nucleobases.

22 base excision repair pathway by locating and excising aberrant nucleobases.

23 denine glycosylases prevent DNA mutations by excising adenine from promutagenic 8-oxo-7,8-dihydroguan

24 n-time of flight mass spectrometry of a band excised after electrophoretic mobility shift assay using

25 equently cotranscriptional, some introns are excised after polyadenylation.

26 o, this exonuclease mechanism allows FAN1 to excise an ICL from one strand through flanking incisions

27 Analysis of all neoformations (155 excised and 140 in follow-up) confirmed these difference

28 melanoma developed at other sites in 9.9% of excised and 9.4% of resected DN.

29 alone to determine if any gland(s) should be excised and auto-transplanted.

30 n, rats were sacrificed, and the brains were excised and divided into three portions.

31 m fibers, pith cells, and vessels under both excised and in vivo conditions in Laurus nobilis In exci

32 The wall of the type 1 big bubble was excised and its grade of scrolling noted.

33 in which two distant parts of a protein are excised and ligated together to form a novel peptide, fo

34 h clinical and/or IVCM examination that were excised and on follow-up of 12 months or longer for the

35 SE) mediate expected levels of recoding when excised and placed in reporter constructs and thus are a

36 After the final CMR, hearts were excised and processed for water content quantification a

37 days postinfection, trigeminal ganglia were excised and profiled by deep sequencing and quantitative

38 in which two distant parts of a protein are excised and then ligated to form a novel peptide, can ge

39 (caC), which were shown to be enzymatically excised and then replaced with an unmodified nucleotide.

40 ith growth on his mandibular ridge which was excised and was proved to be epulis on histopathology.

41 ernal transcribed spacer (ITS) sequences are excised and, as non-functional by-products, are rapidly

42 d regulate primordial germ cells by actively excising and digesting germ cell lobes.

43 hich move within their 'host' genome through excising and re-inserting elsewhere.

44 e (Oryza sativa) MULE, Os3378, is capable of excising and reinserting in yeast (Saccharomyces cerevis

45 Occasionally, ICEs become active, excise, and transmit their DNA to a new recipient, where

46 uctural examination of dislocated lenses and excised anterior capsules was performed.

47 les on the mutant chromosome, we selectively excised approximately 44 kb DNA spanning promoter region

48 ain; 2) midregion C2B-C2C-Fer-DysF, commonly excised as an intact module, with subdigestion to differ

49 Donor common bile duct excised at implantation showed preservation of peribilia

50 ed necrotic part of the greater omentum were excised at surgery.

51 neratedin vitroby deriving virus from a self-excising BAC in fibroblasts and repressing RL13 and UL12

52 Dissociation of the excised base allows TDG to bind the beta rather than the

53 , which might facilitate dissociation of the excised base and enable caC excision, which involves sol

54 structures demonstrate that TDG releases the excised base from its tight product complex with abasic

55 Small RNA profiling after excising beta-catenin from nucleus accumbens in the cont

56 g the appropriate management of incompletely excised, biopsy-proven, mild and moderate dysplastic nev

57 urthermore, ex vivo spectroscopic studies of excised brain tissues demonstrate that the hand-held spe

58 ed variation in xylem sugar concentration in excised branches; (2) changes in carbon allocation in yo

59 an accurate, reliable method to localize and excise breast lesions with acceptable margin positivity

60 -seven paired diagnostic core and surgically excised breast cancer biopsies obtained from women recei

61 ned to streamline the analysis of surgically excised breast tissues by collecting and statistically p

62 The ends of SB transposons excised by a K248A excision(+)/integration(-) transposas

63 opsy was performed by a nondermatologist and excised by a primary care physician.

64 Bulky adducts of this or any type are not excised by DNA glycosylases that use a traditional base-

65 tly, we find that the UBP is not efficiently excised by DNA repair pathways.

66 T) sites, we show that it can be efficiently excised by Flp recombinase site-specific recombination,

67 cation is avoided after the primer strand is excised by the exonuclease and returned back to the poly

68 h resynthesize DNA after the lesion has been excised by the nucleotide excision repair pathway, while

69 A total of 40 pairs of excised cadaver femurs (mean patient age at time of deat

70 d (68)Ga-DOTATATE binding in macrophages and excised carotid plaques.

71 rmed as a secondary treatment in one locally excised case.

72 We examined 71 excised cervical lymph nodes (LNs) from persons with HIV

73 ng enzymes that protect genomic stability by excising chemically modified nucleobases that alter norm

74 actin polymerization in primary cilia, which excises cilia tips in a process we call cilia decapitati

75 alling dynamics in lymphatic endothelium, we excised collecting lymphatic vessels from the popliteal

76 asured action potentials from the surface of excised contracting rabbit hearts to assess when sarcole

77 es is proposed to have induced foundering of excised cumulate material at P > 1.2 GPa.

78 eobases that are substrates for enzymes that excise damaged bases from DNA.

79 erate in this pathway to detect, unhook, and excise DNA cross-links and to subsequently repair the do

80 vitro studies of full PKS modules as well as excised domains.

81 tal polyp(s) that underwent a biopsy or were excised during or after the initial colonoscopy, and obt

82 Our data indicate that excised EndoC-betaH2 cells are highly representative of

83 Thomas et al. (2016) highlight the value of excising enhancer domains, effectively depleting defined

84 Corneas of excised eyeballs were inoculated with green fluorescent

85 We analyzed surgically excised flat-mounted internal limiting membrane specimen

86 Internal eliminated sequences (IES) are excised, followed by rejoining of MAC-destined sequences

87 and their upper gastrointestinal tracts were excised for analysis.

88 Aortic valves that were surgically excised for clinical indications were examined for morph

89 Tumors were excised for histopathology after the final studies on da

90 an albumin-depleted human plasma sample were excised for in-gel MAAH LC-MS analysis.

91 d protein sequencing showed that the NCL was excised from a full-length recombinant substrate, togeth

92 approximately 21-22 nt small RNAs which are excised from a stable hairpin-like secondary structure.

93 Left ventricular papillary muscles were excised from aortic-banded or sham-operated guinea-pig h

94 Guanine-rich sequences that are excised from damaged genomic DNA are proposed to enter t

95 HCN channel activity were uniform in patches excised from distal apical dendritic trunk and tuft site

96 B dependent gene expression, prior to 8-oxoG excised from DNA.

97 annel-activating effects in membrane patches excised from HEK-293 cells.

98 a more physiological environment, membranes excised from HEK293 cells of neuronal origin, would reve

99 d increased adhesion to mesothelial explants excised from mice modeling diet-induced obesity (DIO), i

100 l pruritogens in dorsal root ganglia neurons excised from NC/Nga mice after termination of the studie

101 Therefore, we examined airways freshly excised from newborn non-CF pigs and CF pigs before seco

102 t which DOB is generated within a NCP, it is excised from nucleosomal DNA at a rate 275-1500-fold fas

103 We compare this to a monomeric unit excised from oligomeric FP, which is also dysfunctional

104 e was further investigated on breast tissues excised from prophylactic mastectomy specimens.

105 significantly incorporated but also readily excised from RNA, which may explain its limited efficacy

106 ps that are generated after base adducts are excised from the DNA.

107 erentially-expressed bacterial proteins were excised from the gels and subjected to sequence analysis

108 The captured SCCmec excised from the plasmid and inserted site-specifically

109 unocomplexes on the test line can further be excised from the test-strip for subsequent off-line meas

110 ractions, Mg(2+) or even when the hairpin is excised from the three-way junction.

111 nting Ca(2+)-CaM protein to membrane patches excised from TrpV4-expressing oocytes.

112 ere visualised around O. volvulus in nodules excised from untreated patients but not in nodules from

113 occal cassette chromosome mec (SCCmec), that excises from and inserts site-specifically into the stap

114 xtracts, BER and NER activities co-exist and excise Gh and Sp DNA lesions, suggesting that the relati

115 re, we used in situ x-ray microtomography on excised grapevine stems to determine if embolism removal

116 ment was administered via acute perfusion of excised hearts or isolated cardiac myocytes.

117 novel genome editing techniques that safely excise HIV provirus from cells, Tre, an engineered versi

118 ed women who had been diagnosed with locally excised, hormone-receptor-positive DCIS.

119 mor-infiltrating lymphocytes from surgically excised human carcinomas that were irradiated ex vivo Th

120 this study, we performed IVPT studies using excised human skin (in vitro) and harmonized in vivo hum

121 helper 17 response was stimulated in freshly excised human skin resulting in significantly upregulate

122 rate penetration of the aptamer into freshly excised human skin using two different fluorescent label

123 plasmids (pCMVbeta and pEGFP-N1) into viable excised human skin.

124 This concept is probed using excised human stratum corneum exposed to aqueous solutio

125 y increasing the mechanical extensibility of excised hypocotyl segments.

126 al DNA glycosylase that protects its host by excising ICLs derived from azinomycin B (AZB), a potent

127 with reporter genes that can be subsequently excised improves recovery of edited alleles by an order

128 When patches were excised in darkness TRP remained closed, while when exci

129 ved for Merlin-BAC, from which the vector is excised in derived viruses; however, propagation in epit

130 inal inflammation in mice in which Tbx21 was excised in IL-17-producing or Rag1-expressing cells is i

131 Conjunctival lesions were excised in toto using a standard "no-touch technique" by

132 In excised inside-out macropatches of HEK293 cells, activat

133 most common CF mutation, F508del-CFTR, using excised inside-out membrane patches from transiently tra

134 and purified Gbetagamma proteins applied to excised inside-out patches inhibited TRPM3 currents, ind

135 , including specific guide RNAs (gRNAs), can excise integrated human immunodeficiency virus type 1 (H

136 emonstrated configuration, two alternatively excised internal introns, overlapping by one G, disrupt

137 Contrary to the common belief that excised introns are rapidly degraded, we found that, in

138 y degraded, we found that, in six cases, the excised introns were maintained intact in the cells.

139 The spliceosome excises introns from pre-mRNAs in two sequential transes

140 roteins (snRNPs) and accessory proteins that excises introns from pre-mRNAs.

141 The popliteal and inguinal lymph nodes were excised ipsilateral to the tenotomy site.

142 d base is recognized, they stop to evert and excise it.

143 used data linkage to capture all surgically excised keratinocyte carcinomas arising within the cohor

144 the present comparative study, we conducted excised larynx experiments to investigate this hypothesi

145 owed by histopathology and flow cytometry of excised leaflets.

146 lfate application caused stomatal closure in excised leaves and peeled epidermis.

147 Excised leaves of an Arabidopsis thaliana NAC-LIKE, ACTI

148 histopathological examination confirmed the excised lesion as a heterotopic pancreatic tissue.

149 We extracted DNA from 11 surgically excised lesions from sporadic CCM patients, and sequence

150 defined as agreement with histopathology for excised lesions or clinical diagnosis for nonexcised les

151 actors, clinical and dermoscopic criteria of excised lesions, and results of histopathologic examinat

152 nd corresponding histological examination of excised lesions.

153 Our results reveal that excised liposome patch fluorometry is superior to tradit

154 of arylamine N-acetyltransferases (NATs) in excised liver samples was examined using eighteen Spragu

155 Three to 5 weeks after sacrifice, excised livers were imaged with micro-CT and histologic

156 cellular resolution imaging in MR studies of excised, living tissue.

157 90% of the patients had 12, 7, 14, 6, and 13 excised LNs (10th percentile of the distribution) after

158 These minimum numbers of excised LNs are reproducible across the institution, pat

159 uartile range [IQR]) and mean (SD) number of excised LNs were as follows: 3-level axillary dissection

160 median, and 10th percentile of the number of excised LNs were calculated for the axilla (3 levels), n

161 More excised LNs were detected in younger (21 for those <54 y

162 to collect mechanical test data from freshly excised lung, obtained from both Sprague-Dawley rats and

163 a(+)/bicarbonate cotransporter NBCe1-A in an excised macropatch from the Xenopus oocyte, and indirect

164 ate (PIP2) directly stimulates NBCe1-A in an excised macropatch, and indirectly stimulates NBCe1-B an

165 ries amongst women, the percentage of cervix excised may correlate more accurately to risk than absol

166 Data from 82 freshly excised melanocytic lesions clinically suspected of mela

167 t kinetics of activation and deactivation in excised membrane patches were analyzed as a function of

168 In excised membrane patches, Li(+) increased Ibasal but red

169 The excised membranes were gently moved in a 2.2 intraocular

170 as then exposed to the extracellular face of excised membranes, and transmembrane currents were monit

171 with inverted repeat sequences and a 2.8 kb excised mini-casposon into target DNA.

172 ector system that is based on a pair of self-excising mini-inteins fused in tandem, termed the dual-i

173 Comparative scans of the excised mouse tongue at 7T demonstrated similar midline

174 the DNA This active site can accommodate and excise N3-methylcytosine (3mC) and N1-methyladenine (1mA

175 Of the 155 excised neoformations with a histopathologic diagnosis,

176 insertion profiles (into a skin simulant and excised neonatal porcine skin) were confirmed by texture

177 -or been restricted to biophysics studies of excised neurons probed with cryogenic or bulky detectors

178 All excised nodal packets (n = 36) were assayed for (99m)Tc

179 ExoN excises nucleotide mismatches at the RNA 3'-end in vitro

180 trongest effects were >20 prior skin cancers excised (odds ratio 8.57, 95% confidence interval [95% C

181 hese damages by capturing and sequencing the excised oligomer released during repair.

182 epend on repair/removal of the damage in the excised oligonucleotides, and thus it is applicable to e

183 Use of this probe in surgery either on excised or in vivo tissue has the potential to improve s

184 ning protocols that can be used to transform excised organs and whole organisms into optically transp

185 t; nonetheless, the majority of incompletely excised OSSN (25/28) showed no recurrence.

186 rminal splice junctions, inteins are able to excise out of precursor polypeptides.

187 s, or caused membrane breakdown; however, in excised outside-out patches, Ag NPs activated Gd(3+) -se

188 ial phospholipids, e.g. cardiolipin (CL), by excising oxidized polyunsaturated fatty acid residues, e

189 A 17 C-terminal residues excised p17 was found to be structurally and functionall

190 In excised patch recordings, Gbetagamma subunits (2-250 ng

191 In excised patch-clamp experiments, CFTR activity during ex

192 el TRPV1, contained in proteoliposomes or in excised patches, was exposed to limited trypsin proteoly

193 ocker glibenclamide in both intact cells and excised patches.

194 The Gd content of excised placentae and fetuses was measured, using induct

195 from rehydration and water-release curves on excised plant material, but the underlying tissue-specif

196 n when performing hydraulics measurements on excised plant organs containing living vessel-associated

197 ed micro PET/CT and histological analysis of excised plaque.

198 None of the excised plaques was shown to contain cells (macrophages,

199 tivity of mammalian flap endonuclease (FEN1) excises Pol alpha replication errors in a MutSalpha-depe

200 oss and histological features of operatively excised portions of mitral valves in patients with mitra

201 We examined operatively excised portions of prolapsed posterior mitral leaflets

202 arity metrics were determined from ablations excised postmortem.

203 optically mapped action potentials (APs) in excised rabbit hearts to test the hypothesis that hypoxi

204 s were made from ANF dendrites using acutely excised rat cochlear preparations of different ages afte

205 ring onset by afferent recordings in acutely excised rat cochlear preparations.

206 highlight that estimates of capacitance from excised samples should be interpreted with caution, as c

207 rate the capture and conjugative transfer of excised SCCmec.

208 on variants suggests a function for p27, the excised segment that precedes the fusion peptide in the

209 When combined with a self-excising selection cassette, COIN provides highly effici

210 quire heterologous recombinases to insert or excise selective markers from the target chromosome.

211 boides immediately alleviated by rehydrating excised shoots.

212 cases and none of the lesions that were not excised show any clinical progression under follow-up.

213 We demonstrate this method for excised single neurons from marine worm and squid, and t

214 Lymphocytes were extracted from freshly excised skin SCC tumours and corresponding peripheral bl

215 Tumor relapse in patients with initially excised skin squamous cell carcinomas (SCC) is character

216 ction potential generation in Abeta-LTMRs in excised skin.

217 ficients of exogenously applied compounds on excised skin.

218 d by the Cas1-Cas2 adaptation complex, which excises spacer-sized fragments and channels them for ins

219 ess margins both in the resection bed and on excised specimens for the microscopic presence of cancer

220 rd the healthy surrounding tissue on freshly excised specimens from the oral cavity.

221 Ex vivo microscopy of the excised specimens, stained with fast-acting fluorescent

222 e compartments for capillary water refill in excised stems but rarely under in vivo conditions, (2) h

223 and in vivo conditions in Laurus nobilis In excised stems supplied with water, water uptake exhibite

224 In excised stems that were sealed, fiber and pith refilling

225 Our data show that embolism removal in excised stems was driven by water droplet growth and was

226 The mass was excised surgically at 89 days of life, and the patient h

227 ed changes can be made to modify, ablate, or excise target genes.

228 billion) of additional tax revenues from the excise tax (14% of which would come from the lowest inco

229 d by a 50% increase in tobacco price through excise tax fully passed onto tobacco consumers.

230 association of the first penny per ounce SSB excise tax in the United States, in Berkeley, California

231 ss different wealth quintiles) of a specific excise tax on cigarettes in China in terms of both finan

232 The excise tax would increase overall household expenditures

233 that a 50% increase in tobacco price through excise tax would lead to 231 million years of life gaine

234 among Indian subpopulations facing a 20% SSB excise tax.

235 on of the substrate stereoselectivity of the excised TE domain.

236 AZT(R) RT did not excise terminal nucleotides more frequently than WT, and

237 However, RT also excises terminal nucleotides to a limited extent, and th

238 s multiple DNA processing events required to excise the cross-link from chromatin and resolve the sta

239 presence of Flp-recombinase will effectively excise the expression cassette, leaving behind a single

240 to recognize non-Watson-Crick base pairs and excise the misincorporated nucleotides from the nascent

241 ke nicks 5' to the mispair, allowing Exo1 to excise the mispair.

242 found in the base excision repair pathway to excise the modification.

243 of these proteins were encoded by mRNAs that excise the NP1-regulated MVC intron immediately upstream

244 TDG can excise the oxidative products 5fC and 5caC, initiating b

245 to the evolution of definitive mesoderm, we excised the gene using CRISPR/Cas9 in the diploblastic c

246 t CRIPSR-mediated genome editing efficiently excised the mutant exon 23 in dystrophic mice, and immun

247 yase activity and flap endonuclease 1 (FEN1) excises the 5'-AMP-dRP group along with one or two nucle

248 by Tat during the course of viral infection excises the designated segment of the integrated viral D

249 lycosylase NEIL1, efficiently recognizes and excises the highly mutagenic imidazole ring-opened AFB1-

250 eferentially resolving dC-rC pairs either by excising the mismatched base or switching templates prem

251 rom a single-strand break 5' to the mispair, excising the mispair.

252 se (Int)] is responsible for integrating and excising the viral chromosome into and out of the chromo

253 hen the muscles covering the lch5 organ were excised, the slow relaxation was absent, and the fast re

254 Inteins are parasitic genetic elements that excise themselves at the protein level by self-splicing,

255 teins (or protein introns) autocatalytically excise themselves through protein splicing.

256 grade were surveilled and the remainder were excised, then 97.4% (37 of 38) of malignancies would hav

257 ronuclear genome from somatic macronuclei by excising thousands of internal eliminated sequences (IES

258 aring it to conventional lipid extraction of excised tissue homogenates and by mapping the spatial di

259 Most of the excised tissue samples displayed histological characteri

260 Excised tissue showed 1-2 small (<3.0 cm(2)) healed or h

261 udies have demonstrated that OCT analysis of excised tissue specimens can distinguish between normal

262 s are fast and can be carried out on freshly excised tissue without any tissue preparation, this find

263 zed vessels refilled within tens of seconds (excised tissue) to a few minutes (detached shoots) with

264 Based on bacterial counts from excised tissue, the liver density (0.0079 x 10(10) cfu/g

265 f the tissue analysis, and are restricted to excised tissue.

266 st specimens demonstrate that QMP imaging of excised tissues agrees with flow cytometry and immunohis

267 Imaging was performed on excised tissues as well as intraoperatively in a subset

268 There is a need to image excised tissues during tumor-resection procedures in ord

269 phenotyping (QMP) of the surface of freshly excised tissues to determine the presence of disease.

270 kinetics were assessed in whole tadpoles and excised tissues using gamma spectroscopy, and temporal c

271 rchitectures of collagen-based scaffolds and excised tissues.

272 The number of lesions needed to excise to rule out a melanoma was 2.4.

273 ological status of the margins of the tissue excised to treat cervical precancer.

274 t was determined at 170 locations on freshly excised tongue specimens using the Raman bands of the OH

275 strand breaks (DSB) and the joining of newly excised transposon ends with target DNA.

276 Indeed, the 3,000 bp flanking the excised transposons can contain over 10 times more mutat

277 were performed on representative sections of excised tumors to visualize the distribution of the cons

278 As seen on open abdomen and excised tumors views and confirmed by optical radiant ef

279 Additionally, the excised tumors were scored for inflammatory cell infiltr

280 gic details were missing for a proportion of excised tumors.

281 roids, in mouse tumor models in vivo, and in excised tumors.

282 nuclear human uracil DNA glycosylase (hUNG2) excised two uracil lesions spaced 10-80 bp apart in a si

283 in darkness TRP remained closed, while when excised under illumination it stayed constitutively acti

284 The lesion was excised under local anaesthesia and reported to be a con

285 ial and human DNA glycosylases Nei and NEIL1 excise unhooked psoralen-derived ICLs in three-stranded

286 restriction enzyme (restriction glycosylase) excises unmethylated bases from its recognition sequence

287 the requirement for additional surgeries to excise unremoved cancer tissue or alternatively in the r

288 ted by marker genes, which were subsequently excised using Cre/Lox system for vaccine safety concern.

289 n-mediated chemiluminescent detection of the excised UV photoproduct-containing oligonucleotides that

290 Embolism was experimentally induced in excised vascular tissue and detached shoots by exposing

291 traction of an inflated and axially extended excised vessel provides broader information, both passiv

292 The presence of PFC and plaque in the excised vessels was then confirmed both through ex vivo

293 Uninjured or injured adult hearts are excised, washed and cultured in an incubator with gentle

294 Guided by this screening excise, we showed that netropsin, the specific inhibitor

295 e ability of the tag to measure vibration in excised whiskers in a flume in response to laminar flow

296 ets can distinguish the functional states of excised white, brown, and cold-induced beige fat.

297 Bioluminescent images of living mice, of excised whole intestines, and of whole intestines longit

298 cutaneous melanoma must have been completely excised with adequate surgical margins) who had not rece

299 The cdA and cdG lesions were excised with similar efficiencies, but the efficiencies

300 yocardial oxygenation and KATP activation in excised working rabbit hearts remains unknown.