ライフサイエンスコーパス: excitatory effect

1 ned the ionic mechanism responsible for BK's excitatory effect.

2 antagonist, alpha-helical CRF, blocked this excitatory effect.

3 .0 microM) bicuculline produced non-specific excitatory effects.

4 s indicate that tDCS over the DLPFC has fast excitatory effects, acting on prefrontal and striatal tr

5 y disrupts neuronal activity with an overall excitatory effect and reduces the power of low-frequency

6 The combination of direct excitatory effects and disinhibition induced by activati

7 rexone (NTX) plus fM-nM morphine blocked the excitatory effects and unmasked potent inhibitory effect

8 The serotonin 2C excitatory effects are of lower magnitude and are associ

9 h allyl isothiocyanate and THC mediate their excitatory effects by activating ANKTM1, a member of the

10 clei and the immediately adjacent tegmentum, excitatory effects caused by application of the glutamat

11 ially inhibits GABA release, producing a net excitatory effect during bursts suggesting a mechanism f

12 use these neurons are glutamatergic and have excitatory effects elsewhere, we re-examined the effect

13 of inhibitory effects on the MAP and SNA to excitatory effects following ARCN stimulation was also o

14 rphine and most other opioid agonists elicit excitatory effects, i.e., APD prolongation, at these low

15 rigger withdrawal, nor did it have a greater excitatory effect in dependent rats.

16 tion of mu opioid receptors (MORs) has a net excitatory effect in the hippocampal formation through i

17 venile rat prefrontal cortex, while exerting excitatory effects in adult rats.

18 Serotonin (5-HT) exerts excitatory effects in many brainstem regions involved in

19 rd treatment for neonatal seizures, can have excitatory effects in the neonatal brain, which may wors

20 This excitatory effect is normally present and arises from ce

21 Because NA projects to SON, these excitatory effects may influence the recruitment of inhi

22 ADP, that act together to produce a specific excitatory effect, namely an increased likelihood that a

23 erly compressed DRG in vitro produced potent excitatory effects not observed in control ganglia.

24 er concentrations (7.5 microM), non-specific excitatory effects occurred.

25 The excitatory effect of 8-bromo cGMP was blocked by Rp 8-br

26 sion of AVP would lead to an increase in the excitatory effect of a subthreshold dose of AVP on the a

27 These results suggest that the excitatory effect of acetylcholine on the SON neurons is

28 ly at any dose, but did lead to a sensitized excitatory effect of AVP on startle on Day 2 which was n

29 We report a novel excitatory effect of cannabinoid agonists on action pote

30 The excitatory effect of carbachol was blocked by antagonist

31 ransection of the fimbria/fornix blocked the excitatory effect of corticotropin-releasing hormone (CR

32 This excitatory effect of CRF on PAG neurons may lead to acti

33 Infusion of AVP on Day 1 led to a sensitized excitatory effect of CRF on startle on Day 2 which was n

34 ootshocks given on Day 1 led to a sensitized excitatory effect of CRF on startle on Day 2 which was n

35 ootshocks given on Day 1 would sensitize the excitatory effect of CRF on startle tested 48 h later.

36 igand [D-Pen2,D-Pen5]-enkephalin reduced the excitatory effect of DAMGO in the majority of GH3MORDOR

37 The excitatory effect of DAMGO on seven labeled LC neurons w

38 The excitatory effect of DAMGO was also inhibited by pretrea

39 neuronal firing at baseline but enhanced the excitatory effect of forskolin (an activator of adenylyl

40 esthetics act, in part, by inhibition of the excitatory effect of glutamate at the NMDA receptor.

41 that TRPC3 is a key molecular target for the excitatory effect of IgG-IC on DRG neurons.

42 Importantly, MCH blocks the excitatory effect of kisspeptin on vGluT2-GnRH neurons.

43 revealed pacemaker action potentials and the excitatory effect of local glutamate application, which

44 Ch, nicotine and pilocarpine potentiated the excitatory effect of Na2S2O4 on [Ca2+]i.

45 prompted us to test the hypothesis that the excitatory effect of noradrenergic inputs on oxytocin an

46 This excitatory effect of opioids on primary afferents can co

47 izes clocks and demonstrates an acute direct excitatory effect of PDF on target neurons to control ne

48 We suggest that the known excitatory effect of PGI2 on baroreceptor and vagal affe

49 ect of smoking, thus obscuring a sympathetic excitatory effect of smoking.

50 (nAChR) antagonist mecamylamine blocked the excitatory effect of systemic nicotine on the VTA DA neu

51 r, GABAA receptor pharmacology determined an excitatory effect of the PH on neuroendocrine responses

52 The present data suggest that the excitatory effects of 5-HT on DVN are mediated in part b

53 of strong, direct postsynaptic inhibitory or excitatory effects of 5-HT.

54 T5720) was necessary to block completely the excitatory effects of a ROS donor (tBOOH).

55 Here, we report excitatory effects of AA on a cloned human inwardly rect

56 block (n = 2) or greatly reduce (n = 3) the excitatory effects of alpha,beta-meATP (100 microM, 0.1

57 apine (10.0 mg/kg), in contrast, blocked the excitatory effects of amphetamine on all tested neurons

58 en reduced ongoing activity, and blocked the excitatory effects of ATP.

59 chanism, cocaine sensitizes VTA cells to the excitatory effects of both CRF and orexin-A, thus provid

60 On the other hand, the excitatory effects of both NMDA and AMPA were attenuated

61 o selectively activate mRGCs, simulating the excitatory effects of bright light on this cell type in

62 These excitatory effects of cAMP-PDE inhibitors in naive mice

63 + channels as the primary mechanism of rapid excitatory effects of cocaine and inhibition of centrall

64 y induction of CRF-BP may serve to limit the excitatory effects of CRF in the dentate gyrus.

65 ermine which receptor is responsible for the excitatory effects of CRF on limbic neurons, a selective

66 dogenous opioids may serve to counterbalance excitatory effects of CRF on the LC-norepinephrine syste

67 For a given responsive neuron, the excitatory effects of CRF were reproducible, and there w

68 These results revealed excitatory effects of DA mediated mainly via D2 receptor

69 Possible mechanisms for excitatory effects of E-2 in the mNTS resulting in depre

70 The excitatory effects of EAA were significantly inhibited i

71 omeostatic mechanisms exist to attenuate the excitatory effects of excess glutamate release.

72 extending the duration of, the developmental excitatory effects of GABA, resulting in divergence of t

73 tivity to ischemia, either by modulating the excitatory effects of glutamate or by modifying the inhi

74 ) receptor, which mediates the post-synaptic excitatory effects of glutamate.

75 nine (L-NOARG)), both the inhibitory and the excitatory effects of L-ARG significantly decreased at h

76 The excitatory effects of metabotropic receptor activation i

77 ted cells which become supersensitive to the excitatory effects of mu-, delta- and kappa-opioid agoni

78 nsor may play an important role in mediating excitatory effects of NO in such trigeminal disorders as

79 butyric acid (GABA) may underlie some of the excitatory effects of opioids in the central nervous sys

80 th the general motivational and the specific excitatory effects of pavlovian cues could be assessed i

81 rumental outcome as well as to the selective excitatory effects of reward-related cues in PIT.

82 also contain glutamate which may mediate the excitatory effects of RVL stimulation on SPNs through th

83 and TRH activate RTN chemoreceptors, and (3) excitatory effects of serotonin and pH are mediated by d

84 Recent studies have shown excitatory effects of serotonin on upper airway motoneur

85 ist ketanserin (10 microm) fully blocked the excitatory effects of serotonin.

86 t alpha-methyl-5-HT (30 microm) mimicked the excitatory effects of serotonin.

87 Coupled with previous demonstrations of excitatory effects of SP on sensory neurons, these resul

88 motion assays were used to study the general excitatory effects of the drugs.

89 -Phe to a D-Phe has a dramatic effect on the excitatory effects of the peptide.

90 vasopressin and provide a mechanism for the excitatory effects of vasopressin at physiological level

91 lon and studied the mechanism underlying the excitatory effects of vasopressin.

92 Both inhibitory and excitatory effects of VD4 stimulation on the PeA(I) and

93 d onset (20-30 s after bolus administration) excitatory effect on 21 of 27 units excited by CRD.

94 ta receptors (GH3MORDOR cells), DAMGO had an excitatory effect on Ca 2+ signaling that was mediated b

95 Despite the excitatory effect on Ca 2+ signaling, DAMGO inhibited Ca

96 Opioids have an excitatory effect on CA1 pyramidal neurons in the hippoc

97 Motilin, a peptide hormone has a direct excitatory effect on circular smooth muscle strips deriv

98 ion in vesicles of axon terminals, and their excitatory effect on cultured hypothalamic neurons sugge

99 re, we report that D-amphetamine also has an excitatory effect on DA cells, which under control condi

100 d that CRF had both a direct and an indirect excitatory effect on DMV neurones via activation of CRF(

101 Our data indicate that glucose had no direct excitatory effect on DMV neurones, but DMV neurones appe

102 increase in tonic inhibition is caused by an excitatory effect on inhibitory interneurons was investi

103 Only a small, direct excitatory effect on MSNs by Ex-4 was observed, suggesti

104 MDMA had a predominantly excitatory effect on neuronal activity that was positive

105 eceptors, during parturition and may have an excitatory effect on oxytocin release.

106 It is concluded that CRF has a predominant excitatory effect on PAG neurons.

107 trastriatal neurons in providing a prominent excitatory effect on psychomotor activity.

108 at PACAP-38 exerts a potent and long-lasting excitatory effect on SPNs, leading to an increase of spi

109 l animals, 100 muM carbachol had a transient excitatory effect on spontaneous activity followed by a

110 It was concluded that GES mainly exerted an excitatory effect on T9-T10 spinal neurons with duodenal

111 that bending can also have a slowly-decaying excitatory effect on the CPG's frequency.

112 PMC and SMA, with the latter wielding a more excitatory effect on the diaphragm.

113 higher concentration, CRF had a predominant excitatory effect on the neurons, and at the lower conce

114 ect on the lower esophageal sphincter but an excitatory effect on the upper esophageal sphincter.

115 ents from the vSub to the NAc exert a potent excitatory effect on VTA DA neurons, influencing both DA

116 inspiratory firing patterns associated with excitatory effects on burst timing and pattern.

117 We conclude that Hcrt-2 has excitatory effects on certain SDH neurones, some of whic

118 ten the APD of naive neurons, and evoke only excitatory effects on chronic morphine-treated cells eve

119 Chemokines and gp120 produced excitatory effects on DRG neurons and also stimulated th

120 n the DRN that exert opposing inhibitory and excitatory effects on DRN-5-HT neuronal activity and 5-H

121 cal stimulation induced both suppressive and excitatory effects on neural activity in the DCN of both

122 Studies have shown that glutamate elicits excitatory effects on neurons in the PVN through the NMD

123 ogenetic stimulation of this circuit has net excitatory effects on postsynaptic LHb neurons.

124 It was concluded that (1) ACTH exerts excitatory effects on RVLM neurons resulting in pressor

125 ted whether AVP on Day 1 would sensitize the excitatory effects on startle of CRF given i.c.v. on Day

126 regardless of whether it had suppressive or excitatory effects on these neurons.

127 The excitatory effects on vasomotor neurones, of paraventric

128 effects, whereas the agonist, DOI, produced excitatory effects, on spinal neuronal activity.

129 inhibited striatal and accumbal activity but excitatory effects predominated in both areas.

130 This excitatory effect results from an augmentation of hyperp

131 and reducing [Ca(2+)](e) fails to elicit the excitatory effects seen in the wild-type.

132 The gut peptide ghrelin evoked direct excitatory effects, suggesting these neurons monitor met

133 Cs of the MOB, NA (10 muM) produced a robust excitatory effect that included a slow afterdepolarizati

134 mitter but can sometimes produce paradoxical excitatory effects through synaptic networks.

135 time delay between skin stimulation and its excitatory effect was 15.5 msec.

136 ficantly increased by acetylcholine and this excitatory effect was abolished by atropine.

137 The excitatory effect was dose dependent and was often assoc

138 were not different, but the duration of the excitatory effect was slightly longer than that of the i

139 The excitatory effects were blocked by administration of TTX

140 Although the excitatory effects were distributed across S-, N-, and H

141 Excitatory effects were dose-dependent (over the range o

142 These excitatory effects were mediated by the selective muting

143 ue (M-BLU), cystamine (CYS)), L-ARG had only excitatory effects, whereas its effects were only inhibi

144 -BLU) or cystamine (CYS), NO donors had only excitatory effects, whereas their effects were inhibitor

145 inal cord to promote hyperalgesia through an excitatory effect, which is opposite to the well-known i