ライフサイエンスコーパス: exciting new

1 Exciting new advances in both the basic science and clin

2 The next several years promise to yield exciting new advances in understanding of the genetic ep

3 tered anticancer drugs and is, therefore, an exciting new agent for clinical evaluation for reversal

4 ic and environmental risk factors for AD and exciting new analysis tools for the efficient evaluation

5 kinetoplastid tubulin, GB-II-5 emerges as an exciting new antitrypanosomal and antileishmanial lead c

6 ntrollable, such a transition could bring an exciting new application space to monolayer materials be

7 erspective on the ASC is given together with exciting new applications for the stem cell being consid

8 receptors that target cells of choice is an exciting new approach for cancer, and it holds equal pro

9 eptor subtype 5 (mGlu(5)) have emerged as an exciting new approach for the treatment of schizophrenia

10 Targeted therapies provide an exciting new approach to combat human cancer.

11 ion, reassembly (ADOR) method represents one exciting new approach to obtain solids with targeted str

12 modulation of sodium transport represents an exciting new approach to organ repair.

13 the emerging clinical data coming from this exciting new approach to targeted cancer therapy.

14 This is an exciting new approach to understanding brain function, o

15 ng targeting agents for drugs, are providing exciting new approaches for immunotherapy.

16 l further increase the efficiencies of these exciting new approaches.

17 the cognitive neuroscience of insight is an exciting new area of research with connections to fundam

18 function in vascular surgical patients is an exciting new area of research.

19 roperties, we propose that PEG-HCCs offer an exciting new area of study for the treatment of numerous

20 Image-guided radiation therapy is an exciting new area that focuses heavily on the potential

21 Methyltranscriptome is an exciting new area that studies the mechanisms and functi

22 This realization has opened up large and exciting new areas for the pathogenesis of these disorde

23 sequencing technologies have also introduced exciting new areas of biological endeavour.

24 This review discusses advances in these exciting new areas of drosophila immunity.

25 An exciting new avenue for neurological research and drug d

26 It also suggests an exciting new avenue for therapeutic intervention, as enh

27 mechanosensitive, these findings open up an exciting new avenue of research into the fundamental mec

28 Taken together, the data open exciting new avenues for structure-based drug design.

29 on in an interlocked DNA nanostructure opens exciting new avenues in DNA nanotechnology.

30 f protein trans-splicing may help facilitate exciting new avenues of research and therapeutic applica

31 esses, closing a feedback loop that promises exciting new avenues of scientific exploration at the fr

32 eration of TSCs from fibroblasts, opening up exciting new avenues that may allow the isolation of thi

33 Zinc is proposed as an exciting new biomaterial for use in bioabsorbable cardia

34 Crystalline molecular machines represent an exciting new branch of crystal engineering and materials

35 al and brain sciences may be able to pioneer exciting new breakthroughs in security countermeasures a

36 y, Andrabi and colleagues (2015) identify an exciting new candidate immunogen that could initiate the

37 ersatile E. coli system to be employed as an exciting new carbon capture technology or as a cell fact

38 pathogens has a high probability of yielding exciting new cellular mechanisms and insights into novel

39 Furthermore, we highlight the potential for exciting new cellular therapy using genetically modified

40 Thiazolidinediones (TZDs) constitute an exciting new class of antidiabetic compounds, which func

41 xible design of surface properties with this exciting new class of diamond nanoparticles.

42 led by the anti-CTLA4 mAb ipilimumab, are an exciting new class of drugs capable of promoting antican

43 the future as CLL therapy evolves with this exciting new class of drugs.

44 tation of personalized cancer care with this exciting new class of inhibitors is now becoming a reali

45 PARP inhibitors are an exciting new class of targeted therapy for treating pati

46 genes identified in this study represent an exciting new class of virulence determinants for further

47 Exciting new data have revealed that these enzymes are a

48 ons affecting planar polarity, together with exciting new data in cell and developmental biology, pro

49 Exciting new data indicate that, in at least one system,

50 Finally, we review exciting new data revealing that X chromosomes co-locali

51 Exciting new data suggest that the mobile signal for SAR

52 Together, these exciting new data support a role for SIM2s in promoting

53 An exciting new development in the experimental characteriz

54 The exciting new development is the discovery that even a we

55 articularly successful in this context is an exciting new development that may provide a general solu

56 The cultural intelligence hypothesis is an exciting new development.

57 Exciting new developments and applications of imaging te

58 blurred and how, in turn, this is leading to exciting new developments in the assessment and manageme

59 This review focuses on exciting new developments in the field of mast cell biol

60 Fueled by exciting new developments in the field, the AACR Special

61 The exciting new developments in this rapidly expanding fiel

62 Computational science has led to exciting new developments, but the nature of the work ha

63 es the background of and prospects for these exciting new developments.

64 ing to create active structures has added an exciting new dimension to 3D printing technology.

65 edented in hybrid frameworks and opens up an exciting new direction in rational synthetic strategies

66 An exciting new direction in responsive liposome research i

67 ineate gaps in current knowledge and clarify exciting new directions for research.

68 The latter are exciting new directions for the field that will likely i

69 arrier generation and highlights some of the exciting new directions for the field.

70 come a long way in the past decade, and many exciting new discoveries are bound to be made in the com

71 tion studies of ubiquitin ligases as well as exciting new discoveries of novel classes of E3s and div

72 cause the future promises to be replete with exciting new discoveries that can be translated to impro

73 Exciting new drugs inhibiting fibrosis, cellular hypertr

74 tion of IFN-gamma), these data illustrate an exciting new element of bacteria-host interactions in wh

75 It is an exciting new era for virus ecology and when used in comb

76 An exciting new era has dawned for the prevention and manag

77 An exciting new era in HCV therapy dawned with the recent a

78 cific targeted agents and have ushered in an exciting new era of antileukemia therapy.

79 As we embark upon this exciting new era of B. subtilis comparative genomics we

80 Exciting new evidence indicates that a plant's genotype

81 Exciting new evidence is emerging with regard to their r

82 ation on the regulation of gonocyte fate and exciting new evidence supporting a link between the JAK-

83 An exciting new experiment on the motor cortex of monkeys,

84 These findings provide an exciting new facet of study regarding how pH is regulate

85 pplication of advanced approaches highlights exciting new facets.

86 The next steps in this exciting new field include the development of novel conc

87 Predictive monitoring is an exciting new field involving analysis of physiologic dat

88 stone deacetylases (HDACs) opens yet another exciting new field of discovery in the role of the dynam

89 vailable drugs, which are emerging from this exciting new field of pancreatic cancer research.

90 ture applications of viruses have created an exciting new field within the disciplines of both nanote

91 erdisciplinary collaborations advancing this exciting new field.

92 ip of PNAS to discuss and contribute to this exciting new field.

93 overing the current state of the art of this exciting new field.

94 f organizations that grant privileges in the exciting new fields of CCT/CMR.

95 photonics that could potentially spawn many exciting new fields.

96 No exciting new finding was reported in 2001 specifically a

97 Here I discuss three exciting new findings focused on encoding or replay of s

98 Exciting new findings from Gascon et al. (2016) single o

99 ew, we summarize the recent developments and exciting new findings of cellular functions of IQGAP1.

100 In the past year there have been many exciting new findings on CD8(+) T-cell priming, expansio

101 Here, I summarize exciting new findings that offer the possibility of a qu

102 his Meeting Review, we highlight some of the exciting new findings that were presented, and discuss e

103 n summarizing this line of study is to bring exciting new findings to the attention of the investigat

104 cal electrically excitable cells could yield exciting new findings.

105 e interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable org

106 ponent supramolecular systems could underpin exciting new functional materials, but it is extremely c

107 ramolecular systems could be used to prepare exciting new functional materials, but it is often chall

108 se burden derived from introduction of these exciting new HCV therapies.

109 CC in many human motility disorders suggests exciting new hypotheses for the etiology of these disord

110 These results provide exciting new ideas for rational drug design with RNA as

111 immunologic correlates of control of HIV-1, exciting new immunotherapeutic strategies for HIV-1 infe

112 and their families but it has also provided exciting new information about disease mechanisms involv

113 In sum, this section reviews exciting new information in the areas of childhood diet

114 trials in the near future promises to yield exciting new information on the ability of these compoun

115 Among other developments in the field, exciting new information related to duckweed including g

116 ly improved over the last 30 years, there is exciting new information that may significantly improve

117 Recent in vivo studies have provided exciting new insight into astrocyte physiology in the in

118 luminating a once elusive process, providing exciting new insights and a useful framework of genes an

119 chosocial mechanisms of IBS have resulted in exciting new insights as well as therapies.

120 accumulated rapidly and, in combination with exciting new insights in the cellular origin of these tu

121 Caenorhabditis elegans has not only provided exciting new insights into how the toxins produced by th

122 particularly in the podocyte, have provided exciting new insights into potential pathogenic mechanis

123 d other analytical techniques, have provided exciting new insights into symbiont diversity and the re

124 t on a complex regulatory system and provide exciting new insights into the elusive mechanisms that r

125 Exciting new insights into the fundamental underpinnings

126 the findings of this study not only provide exciting new insights into the human odorant detection o

127 Two recent reports provide exciting new insights into the mode of action of these R

128 l-trans retinoic acid actions, have provided exciting new insights into the molecular basis of vitami

129 The results provide exciting new insights into the process of self-assembly,

130 tive field mapping and, in doing so, provide exciting new insights into the way in which sounds are p

131 transmissibility of the virus are providing exciting new insights into this devastating pandemic str

132 Exciting new insights into treatment of ophthalmologic d

133 lator of HSC transdifferentiation and offers exciting new insights on the therapeutic potential of Re

134 ant scientific problems and may even lead to exciting new insights.

135 enerative medicine, but offer the promise of exciting new interdisciplinary approaches to tissue and

136 h also serves as a roadmap into the vast and exciting new landscape of questions about the computatio

137 hibitors and demonstrate the compounds to be exciting new leads for the development of novel antimala

138 Despite some exciting new leads in molecular pathogenesis, AIDS-defin

139 mor epithelial and endothelial cells provide exciting new leads into effective therapeutic targeting

140 intact in a mass spectrometer has stimulated exciting new lines of research.

141 March 2013 issue of GENETICS establishes an exciting new link between proteins with well-established

142 Cyclic brush polymers represent an exciting new macromolecular topology.

143 Exciting new management strategies appear to be the use

144 These exciting new materials were prepared via rapid, 15 min,

145 and oligonucleotide approaches are yielding exciting new medicines for rare diseases of unmet need.

146 mechanical signaling are beginning to offer exciting new methods for improving neocartilage.

147 (+)CD25(+) cells warrant consideration as an exciting new modality of cellular therapy for the inhibi

148 the level of mRNA polyadenylation, adding an exciting new model for both the RNA processing and plant

149 Human ES and EG cells provide an exciting new model for understanding the differentiation

150 Our results provide exciting new momentum for developing mGluR1-based pharma

151 Our results reveal an exciting new noncoding RNA signaling network that regula

152 oscopy to approximately 10 nm, thus creating exciting new opportunities and challenges for correlativ

153 t article about genomic filtering highlights exciting new opportunities for antiparasitic drug discov

154 hich A3G is regulated within the cell, offer exciting new opportunities for developing novel anti-HIV

155 ased into circulating blood, they also offer exciting new opportunities for developing sensitive biom

156 , and force-mapping techniques are providing exciting new opportunities for future research into bran

157 flavin dynamics in this enzyme class offers exciting new opportunities for inhibitor design.

158 of layered materials, they should offer many exciting new opportunities for studying and even manufac

159 Hence, our findings provide exciting new opportunities for the application of biodeg

160 These data have also opened up exciting new opportunities for the development of entire

161 ue features of MOSCs are expected to provide exciting new opportunities for the exploration of their

162 This model offers exciting new opportunities for therapeutic intervention

163 m infectious agents and cancers has provided exciting new opportunities in prevention and treatment t

164 t properties at systems level, which provide exciting new opportunities in systems chemistry.

165 nt conceptual and technical advances provide exciting new opportunities to close this gap by making n

166 Exciting new opportunities to combine air sampling with

167 technologies are providing researchers with exciting new opportunities to study small-animal models

168 ge compensation, its realization has created exciting new opportunities to study the evolution, mecha

169 Importantly, our studies reveal exciting new opportunities to study virus-host interacti

170 Along with this exciting new opportunity comes a challenge for software

171 Tokonami et al. report on the function of an exciting new paracrine mediator, the mitochondrial the c

172 duced ferroelectric multiferroics present an exciting new paradigm in the design of multifunctional m

173 cular Cell, Kress and colleagues identify an exciting new pathway that downregulates c-Myc translatio

174 In this study, we investigated an exciting new pathway, the exosome-mediated transfer of m

175 Such tests have opened an exciting new phase in biogerontology in which fundamenta

176 ncing tissue regeneration could represent an exciting new phase in medicine.

177 associated large datasets should lead to an exciting new phase of discovery across many areas of bio

178 e critical in the push to commercialize this exciting new photovoltaic technology.

179 roplet-based microfluidics has emerged as an exciting new platform for high-throughput experimentatio

180 This material provides an exciting, new platform to study the properties of Weyl f

181 ial for hepatogenesis and has uncovered some exciting new players.

182 aracterization of artworks in situ and opens exciting new possibilities for cultural heritage researc

183 Diffusion tractography opens exciting new possibilities for exploring features of bra

184 These findings raise exciting new possibilities for how the mRNA localization

185 -generation DNA sequencing platforms provide exciting new possibilities for in vitro genetic analysis

186 into a pluripotent epigenetic state provides exciting new possibilities for in vitro research and cel

187 ble to exercise such control and have opened exciting new possibilities for light manipulation.

188 owing review will update the reader on these exciting new possibilities for patient care and future d

189 pectroscopy is a powerful method that offers exciting new possibilities for structural and functional

190 of mutant embryos without inbred lines opens exciting new possibilities for studying development in l

191 udy of small animal model systems that offer exciting new possibilities in neuroscience.

192 Some of the exciting new possibilities offered by 2D crystals are di

193 field will continue to evolve and grow, with exciting new possibilities stemming from advancements in

194 The 2D monolayer-capping approach opens up exciting new possibilities to enhance the thermal stabil

195 o be fundamental for learning and memory, an exciting new possibility is the extinction of drug-seeki

196 These results suggest the exciting new possibility that Nln is a key enzyme for en

197 ys may contribute to many diseases and offer exciting new potential for therapeutic control via resol

198 These results offer an exciting new potential for type I diabetes mellitus trea

199 nous regulatory T (Treg) cells represents an exciting new potential modality for treating allergic di

200 Taken together, these findings provide exciting new potential targets for therapeutic intervent

201 eptor hormones has led to the development of exciting new potential treatments.

202 us-host disease (cGVHD).1 This represents an exciting new preclinical model that can be used to uncov

203 ady progress with reconstruction algorithms, exciting new processing algorithms have become commercia

204 able in late 2003), it is expected that this exciting new product will be submitted this winter to th

205 Exciting new progress has been made in characterizing th

206 tional perspective, organoid systems provide exciting new prospects for drug discovery, offering the

207 ne expression in Drosophila embryos opens up exciting new prospects for understanding gene regulation

208 To date the promise of exciting new protein-based technologies that can harness

209 These observations raise exciting new questions about the role of glial cells in

210 These results raise exciting new questions regarding potentially dynamic rol

211 An exciting new report describes that leptin can influence

212 Exciting new research aimed at predicting cardiotoxicity

213 control protein synthesis is emerging as an exciting new research area with significant potential fo

214 Altogether, these seven ant genomes open exciting new research avenues and opportunities for unde

215 logies and new animal models, are propelling exciting new research forward.

216 Exciting new research has elaborated several important a

217 Here, we summarize exciting new research into the biology of mTORC2 signali

218 a large Italian kindred is likely to provide exciting new research opportunities but the mutation doe

219 different disciplines and thus provided many exciting new research opportunities in surface and surfa

220 There is exciting new research regarding the variable susceptibil

221 Exciting new research shows that these changes arise not

222 tional top-down engineering design, and that exciting new results from evolutionary engineering desig

223 Exciting new results have increasingly utilized objectiv

224 Exciting new results suggest that lysosomal pH may be dy

225 We highlight exciting new results suggesting that histone variants ar

226 ventional superconductivity in SLG offers an exciting new route for the development of p-wave superco

227 ovements open up qualitatively different and exciting new scientific applications of radio surveys.

228 These pyrazolopyrimidines represent an exciting new series of mTOR-selective inhibitors with po

229 e bacterial platform, opening the door to an exciting new set of applications.

230 this issue of Blood, Zhang et al describe an exciting new small-molecule antagonist of CXCL12-CXCR4 b

231 diates in this recombination pathway provide exciting new snapshots of full length lambda integrase i

232 An exciting new story is that ribosomal proteins are sentin

233 ology and cellular reprogramming has enabled exciting new strategies for cardiac regeneration.

234 w catalytic asymmetric reactions can lead to exciting new strategies for organic synthesis.

235 kinase inhibitors with transplantation is an exciting new strategy and it provides inspiration for si

236 other therapeutic indications may provide an exciting new strategy for the treatment of colon cancer.

237 ranscatheter mitral therapy as a potentially exciting new strategy to improve the lives of patients w

238 ting guanine (G) quadruplex structures is an exciting new strategy with potential for controlling gen

239 Over the past 5 years, exciting new studies have shown that the same signals th

240 In recent years, exciting new studies have suggested that ubiquitin signa

241 In addition, exciting new studies on Fmr1 knockout mice and mutant fl

242 cation can be reversed is not yet known, but exciting new studies suggest that this may be possible i

243 Here we discuss the implications of these exciting new studies.

244 This commentary on an exciting new study (Fusi et al., 2014) puts the finding

245 in palmitoyltransferases (PATs) represent an exciting new target for anticancer drug design due to th

246 threonine kinase Akt/PKB pathway presents an exciting new target for molecular therapeutics, as it fu

247 aemic injury and discuss its potential as an exciting new target for the prevention and/or treatment

248 Hence, Hsp90 is emerging as an exciting new target for the treatment of cancer.

249 osteric modulators of mGluR4 appear to be an exciting new target for the treatment of Parkinson's dis

250 Consequently, mPTPB represents an exciting new target to combat tuberculosis (TB) infectio

251 on disease and novel gene mutations provide exciting new targets for investigation.

252 Thus, PARs are exciting new targets in lung disease research.

253 These data provide exciting new targets that might be essential specificall

254 Together, these advances provide a host of exciting new targets to identify and treat FGIDs and new

255 Tissue engineering is an exciting new technique in bone grafting.

256 precisely the limitations and scope of this exciting new technique.

257 ill also be reviewed, as this is where these exciting new techniques have the potential to revolution

258 Extensions of current research and exciting new techniques promise novel insights into mech

259 Exciting new technologies are often self-limiting in the

260 including disproportionate growth rates and exciting new technologies, have focused attention on car

261 sting results and spurred the development of exciting new technologies, while requiring only readily

262 An exciting new technology allows EcR to be used in chimeri

263 Microarray expression profiling provides an exciting new technology for relating tumor gene expressi

264 Exciting new therapeutic approaches to the treatment or

265 Radioimmunotherapy offers an exciting new therapeutic modality for patients with recu

266 -alpha and/or NF-kappaB signaling to provide exciting new therapeutic opportunities for the treatment

267 des in adipocytes specifically represents an exciting new therapeutic opportunity for the cardiovascu

268 eins into pancreatic islets, thus opening an exciting new therapeutic opportunity to improve the viab

269 disorders, alpha-1 antitrypsin disease, and exciting new therapeutic options for lysosomal storage d

270 ly developing knowledge base and potentially exciting new therapeutic options.

271 lls in an IL-6 independent fashion may offer exciting new therapeutic options.

272 Our findings suggest exciting new therapeutic possibilities to selectively de

273 Based on these findings, exciting new therapeutic strategies have been developed,

274 ug carriers at the 'nano'-scale is providing exciting new therapeutic strategies in clinical manageme

275 Therefore, T-oligos are considered an exciting new therapeutic strategy.

276 Exciting new therapies are currently being tested, which

277 This has opened the possibility for exciting new therapies for obesity and diabetes.

278 r understanding of epilepsy, and to generate exciting new therapies for patients.

279 Metagenome sequencing presents an exciting new tool for assessing microbial diversity in c

280 paramagnetic iron oxide particles provide an exciting new tool to detect the invasion of macrophages

281 edical field and the challenges facing these exciting new tools both in terms of biological activity

282 Computer science provides exciting new tools for archiving, analyzing, synthesizin

283 They provide researchers with exciting new tools to explore how cellular processes are

284 he entrainment of the circadian system is an exciting new topic in retinal neurobiology.

285 Gene therapy is providing exciting new treatment options for patients with PIDs, a

286 In part 2, I identify some exciting new treatment options that are under study.

287 In an exciting new twist, researchers are taking the technolog

288 molecular and anatomical clues forecasts an exciting new understanding of how the germ of youth is a

289 There are many exciting, new vaccines for adolescents.

290 gic to target-oriented synthesis provides an exciting new venue for the development of new and useful

291 It is also allowing us to envision exciting new ways for addressing global health problems.

292 d to reveal science to the general public in exciting new ways.

293 a few key transcription factors provides an exciting new window into the basic biology of pluripoten

294 Synchrotron X-ray imaging provides an exciting new window into the internal workings of small

295 Exciting new work on autophagy-modulating proteins that