ライフサイエンスコーパス: exert

1 n extracellular glycosyltransferase, able to exert a "glycan remodelling" process, even at distal com

2 mine whether motivational-salient cues could exert a differential impact on proactive (the restrain o

3 The smallest colloids exert a disproportionately large influence on colloidal

4 ly, these findings suggest that 5-HT neurons exert a frequency-dependent, cell-type-specific control

5 e granuloma maturation (CCL2, CCL5), (v) may exert a granuloma-independent action that enables self-c

6 ple myeloma, anti-multiple myeloma therapies exert a greater depth of response against multiple myelo

7 tudy indicates that vertical redox gradients exert a major control on the quantity and speciation of

8 BldO now joins pleiotropic repressor BldD to exert a multi-layer control of the temporal and spatial

9 chanism consists of an array of islands that exert a passive inertial lift force on proximate cells,

10 , thaw-induced CH4 emission increases likely exert a positive net radiative greenhouse gas forcing th

11 s early as 2 mo, suggesting that GRP78 could exert a protective effect on acinar cells under stress,

12 rs to influence systemic IDO activity and to exert a significant impact on metastatic risk and overal

13 ina, we conclude that natural emissions also exert a significant influence on the increases in winter

14 ral sediments and terrestrial derived OC may exert a strong influence over OC storage potential acros

15 Vitamin D-enriched mushrooms extracts exert a synergistic anti-inflammatory effect.

16 TGF-beta/Fc and nonlytic IL-2/Fc exert a synergistic effect in promotion of alloengraftme

17 results show that interannual CHL anomalies exert a systematic modulating effect on the solar radiat

18 The coffee samples exerted a cytoprotective effect against oxidative stress

19 cording to baseline depressive symptoms, PSE exerted a preventive effect among those with lower-level

20 We found that core fucosylation exerted a significant adverse effect on FcgammaRIIIA bin

21 conditions of each year; although irrigation exerted a significant effect on several compounds (proli

22 ower risk profiles (pinteraction=0.007), and exerted a significant ischaemic benefit only in this lat

23 y CD11b(+) Ly6G(+) Ly6C(++)-expressing cells exerted a significant suppressive effect on T cell proli

24 nced infarct border-zone capillarization and exerted a sustained beneficial effect on left ventricula

25 argued that melange may suppress calving by exerting a buttressing force directly on the glacier ter

26 ation results in loss of function while also exerting a dominant negative effect on wild-type CARD11.

27 nriched site for a deubiquitinating activity exerting a function in selective stabilization of host p

28 Thus, C1-C2B exerts a basal inhibition on Munc13 in the primed state,

29 sue inflammation, and arterial stiffness and exerts a beneficial shift in gut microbial communities i

30 We show here that R-2HG also exerts a broad anti-leukemic activity in vitro and in vi

31 Because the second messenger cGMP exerts a central role in LTP mechanisms, here we studied

32 protein chains and have suggested that KLK7 exerts a chymotryptic-like cleavage preference.

33 Unexpectedly, we found that wild-type p53 exerts a dominant tumor-suppressive effect on mutant tum

34 our data clearly establish that Ca(2+) entry exerts a feedback control on T-type channel activity, by

35 lumination of the plasmonic tweezer with CPL exerts a force on the microscope tip that depends on the

36 ent limitation of oceanic primary production exerts a fundamental control on marine food webs and the

37 the channel-periphery near the M4 helix and exerts a long-range allosteric effect on the pore across

38 Interaction with Ragulator exerts a negative regulatory effect on BORC that is inde

39 triacylglycerol in Saccharomyces cerevisiae, exerts a negative regulatory effect on the level of phos

40 Thus, CCL5 exerts a novel proresolving role on macrophages when act

41 influence extrastriate cortical circuits and exerts a particularly strong impact on the activity of e

42 Moreover, TRX80 exerts a powerful angiogenic effect in both in vitro and

43 tes the effects of control and independently exerts a powerful influence on outcomes relevant to the

44 Attention exerts a powerful influence on visual perception.

45 relatively innocuous to cells, the d-peptide exerts a prolonged anti-proliferative activity.

46 eational drug, alters sensory perception and exerts a range of potential medicinal benefits.

47 the steric nature of the amine base additive exerts a significant influence on the rate of substrate

48 ring coal by liquid nitrogen (LN2) injection exerts a significant positive effect on the fracture per

49 he studies also show that the aminooxy group exerts a stereoelectronic effect comparable to fluorine

50 Manuka honey (Leptospermum scoparium) exerts a strong antibacterial effect.

51 dies all suggest that the 1,5-triazole group exerts a strong electron-withdrawing effect on carbocati

52 tulated that alpha oscillations, believed to exert active inhibitory gating, downmodulate the tempora

53 Experimental studies show that statins exert additive effects with agents, such as cisplatin, t

54 Foraging intensity of large herbivores may exert an indirect top-down ecological force on soil micr

55 nd through what mechanisms their effects may exert an influence.

56 Influential individuals exerted an overriding effect on risk-taking by the entir

57 dependent in vitro model of angiogenesis and exerts an additive antiangiogenic response with the anti

58 e demonstrate that the contralesional cortex exerts an enhanced interhemispheric inhibition over the

59 In cancer, it exerts an immunosuppressive function as part of an acqui

60 h as hydraulic conductivities or porosities, exerts an important control on water balance.

61 Permafrost exerts an important control over hydrological processes

62 lioma, 6OTD required lower concentrations to exert anti-cancer effects and preferentially affected GS

63 om human amniotic membrane (AM) and known to exert anti-inflammatory and anti-scarring actions.

64 erates at the blood-endothelium interface to exert anti-inflammatory properties is largely unknown.

65 air the TNBC response induced by hypoxia and exert anti-tumour effects.

66 est compound, the (S)-FPMPA amidate prodrug, exerts anti-HIV-1 activity in TZM-bl and peripheral bloo

67 Collectively, our results show that miR-520f exerts anti-invasive and antimetastatic effects in vitro

68 tive triphosphate metabolite, Ara-CTP, which exerts antileukemic effects, primarily by inhibiting DNA

69 ing these results, we have found that MR-409 exerted antioxidant and anti-inflammatory effects in ret

70 is a typical product from Amazon biota that exerts antioxidant capacity due to the presence of pheno

71 ll wall component that induces inflammation, exert appetite-suppressing effects and activate PBN CGRP

72 perience electrostatic repulsion that, being exerted asymmetrically, is predicted to favor membrane c

73 This effect was exerted at multiple levels.

74 Ring-forming AAA+ chaperones exert ATP-fueled substrate unfolding by threading throug

75 Serotonergic fibres exert background 5-HT3R mediated facilitation of both ta

76 strogen receptor modulation, isoflavones may exert beneficial effects against estrogen-deficient bone

77 l-Carnitine (LC) exerts beneficial effects in arterial hypertension due,

78 Recent studies demonstrate that Honokiol exerts beneficial effects on cardiac hypertrophy and dox

79 We hypothesized that TNF exerts beneficial effects on intestinal epithelial cell

80 tal muscle fibers release exosomes which can exert biologically significant effects on recipient cell

81 Anaesthetics have been shown to exert both neurotoxic and neuroprotective effects during

82 organismal context, orthologous proteins may exert both overlapping and opposing functions.

83 otypes.The Ras-family small GTPase RAB25 can exert both pro- and anti-oncogenic functions.

84 It is noteworthy that the complexation exerted by a monosaccharide (glucose or methylglucopyran

85 changes and overall gene-expression effects exerted by CNIs and can even promote Treg expansion by e

86 ntion has been paid to understanding control exerted by community dynamics and biotic interactions.

87 s, suggesting that the environmental filters exerted by drought impact adult tree survival most stron

88 vide new insights into the regulatory effect exerted by JMJD2B on tumor growth through the modulation

89 Radiation pressure exerted by light on any surface is the pressure generate

90 highlights a relatively high genetic barrier exerted by MINI KF116.

91 normal mitosis and impairs the tumorigenesis exerted by miR-26a, indicating that CHFR represents an i

92 ach that does not require selective pressure exerted by NAbs.

93 emonstrate the surprising strength of forces exerted by natural enemies on herbivorous insects, and t

94 ility of a direct gene expression regulation exerted by RALY.

95 bind Abeta-peptides and the positive effect exerted by some TTR stabilizers for modulating the TTR-A

96 nvolvement of AMPK in the beneficial effects exerted by strawberry against aging progression.

97 Torques exerted by sublimation measurably influence the spin rat

98 The nonequilibrium forces exerted by the active bath on the inclusions or boundari

99 experimental measurements, the shear stress exerted by the cilia is deduced.

100 The regulation exerted by the CPuORF was tissue specific and did not ac

101 The modulation exerted by the cytoskeleton onto the nucleus results in

102 ements suggest that the contractile stresses exerted by the leukocytes and the VECs can separately pe

103 ordinated fashion to regulate chemorepulsion exerted by the muscle.

104 nthine plane because of the steric hindrance exerted by the two carbonyls.

105 nisms that regulate the balance of influence exerted by the two eyes on cortical mechanisms underlyin

106 The forces exerted by these acoustic vortex fields on a levitated w

107 ing biochemical reactions as a ROS source to exert cancer death.

108 Strikingly, cGAMP exerts cell-type-specific anti-inflammatory effects on m

109 We conclude that the GR in adipocytes exerts central but diverging roles in the regulation of

110 nt with previous findings, KLK7 was found to exert chymotryptic-like cleavage preferences.

111 the multitarget-directed ligand paradigm to exert combined activity at human fatty acid amide hydrol

112 Experimentally, DHI exerted comprehensive anti-inflammatory effects on LPS,

113 Thus, LIS1 exerts concentration-dependent effects on dynein motilit

114 leosome core particle (NCP) is considered to exert constraints to all DNA-templated processes, includ

115 ovel mechanistic arguments as to why AES may exert context-specific beneficial or adverse effects in

116 Reactive mineral-water interfaces exert control on the bioavailability of contaminant arse

117 this variability is the agentic decision to exert control over emotional responses.

118 s, these results reveal that climbing fibers exert control over inhibition at both the input and outp

119 entally realize quantum phases of matter and exert control over their properties is a central goal of

120 To exert control over this rate-limiting step, we designed

121 iated genes, integrates external signals and exerts control over the decision between self-renewal an

122 nstituents in the extract were identified to exert cyto-protective effect.

123 Two R. sempervirens extracts exerted cytotoxic activity against HeLa and HT-29 cell l

124 eleased from cells with different phenotypes exert different functions in order to protect tissue and

125 Each lipid in concern exerted different effects on the digestibility of starch

126 In addition, these domains exert differential effects on spatial and contextual lea

127 further suggests that the central NPY system exerts differential effects on the sequential phases of

128 This influence can be exerted directly upon the primary motor (M1) and somatos

129 Notably, two isoforms of OPN exerted distinct effects in shifting this balance throug

130 These findings suggest that SFK and FAK exert distinctive molecular hierarchy depending on their

131 OCs) direct microtubule (MT) organization to exert diverse cell-type-specific functions.

132 ass of ionotropic glutamate receptors, which exert diverse pre- and postsynaptic functions through co

133 mental exposures to non-mutagenic agents can exert effects in unexposed descendants.

134 tors released by irradiated cells or tissues exert effects on other parts of the animal not exposed t

135 r and molecular pathways along which hypoxia exerts effects on nephrogenesis are not well understood.

136 We found that participants (N = 118) exerted effort to avoid disaster-associated states, adju

137 Our data show that GAS exerts enhanced anti-cancer properties in vitro and supe

138 These results suggest that Lsh exerts epigenetic regulation at key regulators of neural

139 patients with acute heart failure, ularitide exerted favorable physiological effects (without affecti

140 as a novel antidiabetic class of drugs that exert favourable results in a variety of other cardiovas

141 show that the right frontal-eye field (rFEF) exerted feedback control of the visual alpha oscillation

142 must be endocytosed after it binds Notch to exert force that exposes an otherwise buried site for cl

143 less is known about how cells adhere to and exert forces in soft, three-dimensional (3D), and struct

144 s undisturbed, the buried oil is unlikely to exert further negative effects on the biota in spite of

145 s, mastic oil, as a combination of terpenes, exerts growth inhibitory effects against colon carcinoma

146 carriers of functional miR-4443, which might exert heterotypic regulation of PTPRJ gene expression in

147 Northomicrodon parasitism can exert high fitness costs to a host colony.

148 tatic tumor cells and basal-like tumor cells exert higher integrin-mediated traction forces at the bu

149 Roots need to exert higher penetration force, resulting in increased p

150 Post-AIT sera exerted IgE-blocking activity.

151 ly synthesized by mononuclear phagocytes and exerts immunoregulatory functional activities on lymphoc

152 This finding suggests that hRPA exerts important regulatory influence over RAD51 and may

153 They exert indentation, segmentation, and termination on the

154 op can affect the expressed Ig repertoire by exerting influences on the distribution of expressed VH

155 Natural flavonoids exert innumerable pharmacological effects in humans.

156 high regioselective control that PT domains exert is hindered by the inaccessibility of intrinsicall

157 Their findings indicate that p53 may exert its "guardian of genome" duties at least in part v

158 r, the cell(s) upon which IFN-lambda acts to exert its antiviral effects is unclear.

159 ns as a motor or as an actin cross-linker to exert its essential role is disputed [1, 4, 5].

160 nt BTK kinase inhibitor (CHMFL-BTK-11) which exerted its inhibitory efficacy through a covalent bond

161 both as a neurotransmitter and as a hormone, exerting its functions via dopamine (DA) receptors that

162 onsequently, we hypothesize that deguelin is exerting its toxic effect on nematodes as a modulator of

163 re the expression of a global mechanism that exerts its action across the entire visual field.

164 ts suggest a novel mechanism(s) by which HNK exerts its anti-tumor activity through the inhibition of

165 These results suggest that Ifit2 exerts its antiviral effect mainly at the level of viral

166 study provides a novel mechanism by which HN exerts its cardioprotective and neuroprotective effects.

167 an unexpected, cell-autonomous feature that exerts its detrimental, highly aggressive growth potenti

168 In contrast, BRCA2 exerts its effect on HR in human cells together with HsR

169 GD1a exerts its effect on OPCs by inducing their proliferatio

170 effects, which can last several months, and exerts its effects by specifically cleaving and inactiva

171 of the mechanisms by which GLP-1R activation exerts its effects in preventing or arresting experiment

172 However, it remains unclear whether MSA exerts its effects on cancer prevention by influencing a

173 th characterization revealed that circCCDC66 exerts its function via regulation of a subset of oncoge

174 us studies have therefore suggested that MT2 exerts its inhibitory effect by inactivating HJV.

175 low us to propose a mechanism by which Psb28 exerts its protective effect on the RC47 intermediate.

176 Morphine exerts its rewarding actions, at least in part, by inhib

177 ing as opposed to visual processing, that it exerts its strongest influence on spatial choices when d

178 t can manipulate when, where, and how a drug exerts its therapeutic effect.

179 thway is a novel mechanism by which ketamine exerts its therapeutic effects on stress-induced cogniti

180 As/Sb-jarosite can increase Sb mobility and exert major influences on As partitioning and speciation

181 occur consistently within </= 12 h every day exerts many cardiometabolic benefits.

182 Cancer cells exert mastery over the local tumor-associated stroma (TA

183 Cells are physical objects that exert mechanical forces on their surroundings as they mi

184 properties of MK-801 binding site blockers, exert microtubules stabilizing properties, and possess t

185 TMN), extend fibers throughout the brain and exert modulatory influence over numerous physiological s

186 As it becomes possible to exert more control over larger numbers of qubits, such s

187 cells isolated from tumor-bearing mice also exerted morphology of tumor-associated macrophages and e

188 The results show suramin and heparin exerted multiple concentration-dependent effects.

189 nd non-myocytes are known to communicate and exert mutual regulatory effects.

190 esin FimH, where the C-terminal pilin domain exerts negative allosteric control over binding of the N

191 while an enzymatically inactive form of TAK1 exerts no effect.

192 Newly developed targeted therapy can exert off-target effects causing hypertension, thromboem

193 The influence that neurons exert on astrocytic function is poorly understood.

194 tion of the effects that parasite infections exert on populations of commensal gut microbes of veteri

195 hat remotely controls the magnitude of force exerted on a single MPN.

196 s used to investigate the selective pressure exerted on parasite populations by use of RDTs for diagn

197 ) basket cells and the inhibitory drive they exerted on pyramidal cells were reduced in conditional m

198 aterial properties and the mechanical forces exerted on them.

199 f species as well as the selective pressures exerted on viruses to antagonize it.IMPORTANCE Viruses i

200 es of syringeal elements, forces and torques exerted on, and motion of the syringeal skeleton during

201 the distinctive influence that each emotion exerts on perceptual, cognitive, and motor responses.

202 ssential roles during normal development and exert oncogenic functions during tumorigenesis.

203 Many mutant p53 proteins exert oncogenic gain-of-function (GOF) properties that c

204 Many mutant p53 proteins exert oncogenic gain-of-function (GOF) properties that p

205 t ways in which highly similar molecules may exert opposing effects on neurons.

206 Hence, TSPY and TSPX exert opposing effects on the transactivation functions

207 We found that NLRX1 exerted opposing regulatory effects on viral activation

208 irst example that a single auxiliary subunit exerts opposite effects on evolutionarily related channe

209 Electromagnetic waves are known to exert optical forces on particles through radiation pres

210 ploit this dual concept, we developed agents exerting partial FXR agonism and sEH inhibitory activity

211 Heme catabolism exerts physiological functions that impact health throug

212 vivo evidence that noncanonical TR signaling exerts physiologically important cardiometabolic effects

213 Although C1QBP has been reported to exert pleiotropic effects on many cellular processes, we

214 etinoic acid, a hormone-like compound, which exerts pleiotropic and dominant effects on gastrointesti

215 Nitric oxide (NO) exerts pleiotropic effects on plant development; however

216 une cells in the tumor microenvironment that exert potent effects on cancer metastasis.

217 unts of diverse cytokines on activation that exert potent immune regulatory function.

218 e T-cell receptor coregulatory molecule GITR exert potent therapeutic activities in preclinical tumor

219 Notably, JNK inhibitors exerted potent antifungal therapeutic effects in both mo

220 SzV-1287 exerts potent analgesic and anti-inflammatory actions in

221 murine model of SHH-subtype medulloblastoma exerts potent antitumor effects.

222 We found that neuronal activity exerts potent control of global and synaptic K63-polyUb

223 Deguelin exerts potent nematocidal activity via the mitochondrial

224 Pacemaker neurons exert powerful control over brain circuit function, but

225 neurons, although relatively few in number, exert powerful control over brain circuits.

226 MicroRNAs (miRNAs) exert powerful effects on immunity through coordinate re

227 To assess whether neutrophils exert predominantly protective or deleterious effects on

228 cal role in many physiological processes and exerts profound effects on behavior by regulating neuron

229 Gal-3 also exerts proinflammatory effects, at least in extracardiac

230 troalkene fatty acids are formed in vivo and exert protective and anti-inflammatory effects via rever

231 ecreted from the iPSC-derived cardiomyocytes exert protective effects by transferring the endogenous

232 l studies show that PDE5 inhibitors (PDE5is) exert protective effects in DN improving perivascular in

233 IL-27 exerts protective effects in autoimmune diseases like ex

234 Studies suggest that NGB exerts protective effects to neuronal cells and is impli

235 -related cues, thereby allowing such cues to exert relatively greater control over behavior.

236 ion, others lower the level of cognition but exert relatively stable effects over time.

237 997/98 and 1982/83, referred to as super EN, exerted remarkable global influence.

238 ivation of the GR in kidney epithelial cells exerted renal benefits, including inhibition of albuminu

239 Mechanistically, elevated ILF2 expression exerts resistance to genotoxic agents by modulating YB-1

240 l unifying mechanism whereby marijuana could exert rewarding and addictive/withdrawal effects.

241 in response to radiation, and CPR-4 seems to exert RIBEs by acting through the insulin-like growth fa

242 in pentacyclic triterpenic compounds, which exert several biological activities.

243 acutely affect DAT availability will likely exert significant impact on both normal and pathological

244 Additionally, the five tested ITCs exerted significant spasmolytic activity (on rat distal

245 t RAS2 acts via a cAMP-dependent pathway and exerts significant metabolic control on the Neurospora c

246 s SPZ1-TWIST axis mediates EMT signaling and exerts significant regulatory effects on tumor oncogenes

247 However, samples formulated with OLE exerted similar antiglycative capacity against pentosidi

248 hereas the neurosteroid pregnenolone sulfate exerted similar effects as progesterone, likely binding

249 omega-3 PUFAs exerted similar effects on the differentiation of CD4+ T

250 is a technique for preserving food that may exert some effects on mycotoxins.

251 tudies suggest that these inhibitory neurons exert some form of divisive inhibition on the pyramidal

252 oxidation and growth, inferring that Mcp may exert some sort of functional connection between As(III)

253 ctively, our studies suggest that olanzapine exerts some of its untoward metabolic effects via antago

254 Thus, in risky habitats, sharks can exert strong ecological impacts even though they are tro

255 nships along saturated carbon frameworks can exert strong influence over molecular conformation due t

256 ecause it remains unclear whether frugivores exert strong selection on fruit traits.

257 ce food webs tend to host fewer invaders and exert stronger biotic resistance compared to low-connect

258 The combination of cGAMP and PD-L1 antibody exerted stronger antitumor effects than did either treat

259 ation gene 3 protein (LAG-3), and CD49b, and exert strongly suppressive functions toward allergic res

260 ombospodin-1 played an important role in ACM-exerted synaptogenic effects.

261 The interventions appeared to exert the most global benefit in mice that were most met

262 ether, M2-like macrophages in fibrotic liver exert the protective effects against lethal insults thro

263 The O2 concentration exerted the strongest control on net N2O production with

264 he local, geometric frame of reference often exerted the strongest control over the grids, the remote

265 c farming and in-field plant diversification exerted the strongest effects on pollinators and predato

266 packet to the struck proton and its moiety, exerting the force [Formula: see text] The resultant ene

267 vide a molecular mechanism by which puerarin exerts the anti-oxidative effects in podocytes in the di

268 ructure to the least extent, whereas glycine exerts the greatest influence on the water structure.

269 e a low-frequency CYP2R1 coding variant that exerts the largest effect upon 25OHD levels identified t

270 Yet, which driver exerts the largest influence on ecosystem functioning an

271 citing mucosal lesions as long as the toxins exert their action on the epithelium.

272 nic AMPs bind negatively charged bacteria to exert their antimicrobial activity.

273 ough the mechanisms through which probiotics exert their beneficial effects are largely unknown.

274 g lines of evidence indicate that stem cells exert their beneficial effects mainly through secretion

275 stent with the idea that these interventions exert their beneficial effects, in part, by modulation o

276 al through the JAK/STAT signaling pathway to exert their biological effects.

277 , we found that doxycycline and rifamycin SV exert their effect by binding to oligomeric species both

278 previously intractable human diseases but to exert their effects on cellular RNA processing they must

279 re no longer necessary but might continue to exert their effects on recipient cells.

280 d by the anti-diabetic sulfonylurea drugs to exert their full glucose-lowering effects.

281 Since miRNAs exert their functions by regulating the expression of th

282 nes, yet the extent to which recurrent SCNAs exert their influence through rearrangement of cis-regul

283 gulated in their subcellular localization to exert their local function.

284 stinal barrier and reach the blood stream to exert their physiological action.

285 of (GR)50, suggesting that (PR)50 and (GR)50 exert their toxicity through partially distinct mechanis

286 ase risk may result from regulatory variants exerting their effects only in the presence of immune st

287 pharmacological inhibition has been shown to exert therapeutic efficacy in chronic obstructive pulmon

288 Rescue experiments suggest that Spz3 can exert these effects only over very short distances.

289 miR-124-3p exerted these effects by targeting PDE4B, thus inhibitin

290 ocess and potential mechanism(s) by which it exerts these effects.

291 Mechanistically, VEC exerts this effect by inhibiting polycomb protein activi

292 morrhagic stroke outcome, suggesting that it exerts thrombolytic effects without significantly impair

293 eveals that tight control of brain volume is exerted through a large community of mTOR-related genes.

294 hosphorylated alpha-synuclein is believed to exert toxic effects at the synapse in dementia with Lewy

295 nd B cell-dependent autoimmune disorders but exert toxicity from inhibition of proteasomes in other c

296 Myc oncoproteins exert tumorigenic effects by regulating expression of ta

297 Overall, the GDNF-Ret pathway exerts two critical and distinct functions in the periph

298 a single metabotropic receptor subtype, ACh exerts two opposing actions in cortical pyramidal neuron

299 verse pathophysiological mechanisms, cocaine exerts various adverse effects on the cardiovascular sys

300 n against nonmelanoma skin cancer (NMSC) are exerted via signaling mechanisms involving the vitamin D