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1 nd potential traumatic brain injury may also exert an effect.
2 while an enzymatically inactive form of TAK1 exerts no effect.
3 tral regulator HilD was essential for Pat to exert its effects.
4 fy the molecular mechanism of how glypican 4 exerts its effect.
5 d by which astrocyte [Ca(2+)]i is raised and exerts its effects.
6 to provide insight into how corticosteroids exert their effects.
7 both drugs share a binding pocket in SUR1 to exert their effects.
8 ocess and potential mechanism(s) by which it exerts these effects.
9 into cells via RME in the first 24 h period exert cytotoxic effect.
10 ne bind to the serotonin 5-HT1A receptor and exert opposite effects.
11 tumor suppressor genes, such as STK11/LKB1, exerts similar effects.
12 Substance P and its truncated receptor exert oncogenic effects.
13 ion determines the availability of metals to exert biological effects.
14 urs and whether chemically similar molecules exert comparable effects.
15 attrition, amount of food and begging effort exerted additive effects.
16 d induced apoptosis, whereas MEK1 inhibition exerted cytostatic effects.
17 uring positive autobiographical recall could exert antidepressant effects.
18 ombospodin-1 played an important role in ACM-exerted synaptogenic effects.
19 osin-related kinase A (TrkA), and to thereby exert neuroprotective effects.
20 nsfer of eosinophils into IL5-deficient mice exerted prometastatic effects.
21 y, providing a novel mechanism whereby IGF-1 exerts antiatherogenic effects.
22 ongs to the active form of GSK3beta known to exert neuroinflammatory effects.
23 strogen receptor modulation, isoflavones may exert beneficial effects against estrogen-deficient bone
25 Guanabenz and Sephin1) have been proposed to exert protective effects against misfolding by interferi
26 tioxidants contained in these seasonings may exert protective effects against oxidative stress along
27 e BSG protein hydrolysates (fraction <10kDa) exerted protective effect against free-radical induced c
28 ly, these results strongly indicate that Myr exerts cardioprotective effects against DCM through the
29 acts as a powerful CR proxy in dementia and exerts neuroprotective effects against neurodegeneration
33 that most new mutations that affect fitness exert deleterious effects and that natural populations a
34 , the mechanisms utilized by HIV-1 clades to exert differential effects and the methamphetamine (METH
35 ular mechanisms by which association signals exert their effect and (2) suggests that salt sensitivit
38 ctivity is one of the mechanisms by which it exerts mucoprotective effects and that counter-regulator
39 he molecular mechanisms of how liprin-alpha3 exerts this effect and counteracts mDia1 activation by R
40 and fermentable fiber, have been proposed to exert chemoprotective effects, and their molecular mecha
41 HuMC function, the mechanisms by which IL-6 exerts its effects, and the relationship of these findin
43 n (CMVIG) preparations have the potential to exert immunomodulatory effects as well as providing pass
44 hereas the neurosteroid pregnenolone sulfate exerted similar effects as progesterone, likely binding
46 hosphorylated alpha-synuclein is believed to exert toxic effects at the synapse in dementia with Lewy
47 regions of the F. tularensis chromosome, but exerts regulatory effects at only a few of these locatio
48 Taken together, these results reveal c-MYC exerts suppressive effects at several critical checkpoin
51 these findings suggest that pridopidine may exert neuroprotective effects beyond its role in allevia
54 suggest that affirmation of core values may exert its effects by allowing at-risk individuals to see
55 ecreted from the iPSC-derived cardiomyocytes exert protective effects by transferring the endogenous
57 , we found that doxycycline and rifamycin SV exert their effect by binding to oligomeric species both
58 class of putative physiological activators, exert their effect by changing membrane properties, lead
61 bservations demonstrate that NAMPT knockdown exerted antiatherogenic effects by promoting cholesterol
66 mune cells, such as Th2, ILC2, and basophils exerting their effect by production of IL-4, IL-5, and I
67 he effect of KCNE3 on KCNQ1 channels, mainly exerting their effects by an electrostatic interaction w
68 t lipid metabolism, we hypothesized that BaP exerts anticancer effects by disrupting lipogenesis.
69 icagrelor, beyond its antiplatelet efficacy, exerts cardioprotective effects by reducing necrotic inj
71 SFDA approved "epigenetic drug", Decitabine, exerts its effect by hypomethylating DNA, demonstrating
72 effects, which can last several months, and exerts its effects by specifically cleaving and inactiva
74 ) signaling, a natriuretic peptide receptor, exerts renoprotective effects by stimulating natriuresis
76 ngiogenesis and have demonstrated that ZNF24 exerts this effect by repressing the transcription of VE
77 lso alter protein structure and function and exert biological effects directly by binding to free thi
79 Collectively, we demonstrate that microglia exert beneficial effects during a diphtheria toxin-induc
80 ed whether N-n-butyl haloperidol (F2), which exerts protective effects during myocardial I/R injury,
81 urveys the proposed mechanisms by which they exert their effects, from the nucleus to the cellular me
83 D1 (D1R-MSN) vs. D2 receptors (D2R-MSN) can exert antagonistic effects in drug-related behaviors, an
88 results indicate that human Vdelta2 T cells exert proinflammatory effects in CD that are modified by
89 l studies show that PDE5 inhibitors (PDE5is) exert protective effects in DN improving perivascular in
91 the mechanisms and targets through which GCs exert therapeutic effects in diseases such as asthma rem
92 These findings suggest that BET inhibitors exert therapeutic effects in leukemia by evicting BRD4-N
93 inoid epoxides 17,18-EEQ-EA and 19,20-EDP-EA exerted antiangiogenic effects in human microvascular en
97 ond messenger in the central nervous system, exerting physiological effects in target cells by bindin
98 ic compartment-specific IFN-gammaR signaling exerts additive effects in orchestrating intracerebral i
102 Human and murine studies showed that GM-CSF exerts beneficial effects in intestinal inflammation.
105 Until now it was not known whether GABA exerts its effects in plants through the regulation of c
106 of the mechanisms by which GLP-1R activation exerts its effects in preventing or arresting experiment
112 to determine whether carbamylated LDL (cLDL) exerts prothrombotic effects in vascular cells and plate
113 ough genetic or pharmacological MGL ablation exerts therapeutic effects in various preclinical diseas
116 hese data indicate that CD4(+) NKT cells can exert proatherogenic effects independent of other lympho
120 The scaffolded nontransdifferentiated hMSCs exerted multimodal effects of neurotrophism, angiogenesi
121 finity catecholamine conformation while also exerting agonist effects of its own through a secondary
123 cytoskeletal regulator tropomyosin 4 (TPM4) exert an effect on the count and volume of platelets.
124 cy contaminants in polar bear adipose tissue exert antagonistic effects on PPARG, but adipogenesis by
125 (PD-L1), but it remains unknown whether they exert any effects on B cells, the other component of the
127 es that consist of 2-20 amino acids that can exert beneficial effects on human health in addition to
128 ell senescence and allow them to continue to exert beneficial effects on oocyte and sperm, thereby ex
134 that selective CD28 blockade and belatacept exert different effects on mechanisms of renal allograft
135 These observations suggest that WNK4 can exert differential effects on NCC, depending on the intr
136 on, we show that specific Jun family members exert differential effects on proliferation in prostate
138 s the programmed death ligand (PD-L1), might exert differential effects on T-cell function, depending
140 ule cytoskeleton and the JIP3 protein UNC-16 exert distinct effects on localization of axonal and som
141 more slowly conducting CST axons, as well as exert disynaptic effects on motoneurons via interposed i
142 ement, the S4s in the voltage-sensor domains exert downstream effects on the S6 segments to control i
143 cumulating evidence has shown that pathogens exert extensive effects on plant hormone pathways not on
146 perturbations by probiotics and antibiotics exert modulatory effects on some of these measures in ad
147 enzyme is fully functional and therefore may exert mutational effects on both viral and host cell DNA
149 sted that dorsal and ventral mPFC subregions exert opposing effects on fear, as do subregions of othe
151 lence, illustrating that a single factor may exert opposing effects on pathogenesis in distinct host
154 ecause oncogenic and normal ABL1 kinases may exert opposite effects on cell behavior, we examined the
156 s Raf and PI3K have a Ras-binding domain but exert opposite effects on Leishmania infection, we exami
159 However, because brefeldin A is known to exert pleiotropic effects on the entire endosomal system
160 ile pharmacological doses of HDAC inhibitors exert positive effects on Bdnf gene transcription, the i
163 ays, an event frequently observed in cancer, exert profound effects on genome stability via MRE11 wit
164 mosphere associated with climate change will exert profound effects on rice cropping systems, particu
165 ablished that precise glycosylation patterns exert profound effects on the biological activity of IgG
166 g nutrient starvation of cancer cells likely exert profound effects on their capability for metastati
167 resent data indicate that gammadelta T cells exert protective effects on the hearts of mdx mice, poss
168 n findings indicate that ankle-foot orthoses exert significant effects on coronal and sagittal plane
169 losteric modulators of GABAA receptors would exert similar effects on brain activity as ketamine, but
171 ealed how common cancer-associated mutations exert their effect on telomerase after cells differentia
172 previously intractable human diseases but to exert their effects on cellular RNA processing they must
177 's disease, with aSyn aggregates believed to exert toxic effects on neurons, while prolyl oligopeptid
178 ar though if exposure to these chemicals can exert toxic effects on the host and gut microbiome.
179 that Cx26 mutants that promote cell death or exert transdominant effects on other connexins in kerati
181 and PPP showed a similar protein profile and exerted comparable effects on bone differentiation.
188 ultiple alcohol-containing organic compounds exerted inhibitory effects on the Nlrp3 inflammasome, wh
190 -expressing stem cells in crypts, but rather exerted its effects on intermediate progenitors, in part
191 t alteration of OR expression in Arabidopsis exerted minimal effect on PSY transcript abundance.
192 contrast, inhibition of IL-6 trans-signaling exerted minor effects on the immune response and did not
195 manipulation of PPN cholinergic cell bodies exerted opposing effects on locomotor behavior and reinf
197 sion analysis, all statins except lovastatin exerted protective effects on PD incidence and had a sig
198 ing reporter assays where all tested regions exerted regulatory effects on transcription in epithelia
199 choice behavior [7] revealed that tolcapone exerted selective effects on inequity aversion, and not
201 that HvgA and capsule, but not the beta-h/c, exerted significant effects on colonization of the murin
203 mbination with sorafenib (100 mg/kg, orally) exerted synergistic effects on tumor suppression, as com
204 f MS, phase rim lesions continue to smolder, exerting detrimental effects on affected brain tissue.
206 acetylation of histone H4, but not H3, while exerting no effect on the expression of BRD proteins.
207 nia stimulates breathing while theoretically exerting opposite effects on central respiratory chemore
209 d-dependent TOP1-mediated nicking-a strategy exerting quantitative effects on eRNA expression in regu
212 Recent studies demonstrate that Honokiol exerts beneficial effects on cardiac hypertrophy and dox
213 and other biological properties, potentially exerts beneficial effects on endothelial function (EF).
216 e human immunome, and we demonstrate that HC exerts differential effects on B and T lymphocytes and n
217 further suggests that the central NPY system exerts differential effects on the sequential phases of
219 we demonstrate that signaling through c-Kit exerts distinct effects on EAE susceptibility in male an
220 rent results therefore suggest that the VP-m exerts distinct effects on the VTA and MD and that these
222 c acid (UCA), a filaggrin breakdown product, exerts immunomodulatory effects on dendritic cells.
227 However, it remains unclear whether MSA exerts its effects on cancer prevention by influencing a
228 re detailed knowledge about how hyperthermia exerts its effects on chemotherapy may illuminate ways t
229 In sum, our results suggest that TMEM106B exerts its effects on FTLD-TDP disease risk through alte
230 of USP19-ER, suggesting strongly that USP19 exerts its effects on fusion through its effects on UPR
235 irst example that a single auxiliary subunit exerts opposite effects on evolutionarily related channe
236 rotein C pathway, activated protein C (aPC), exerts pleiotropic effects on coagulation, fibrinolysis,
238 nsulin resistance, whereas exercise training exerts positive effects on substrate handling and improv
240 cal role in many physiological processes and exerts profound effects on behavior by regulating neuron
242 were also assessed in vitro and in vivo OSM exerts proinflammatory effects on cultured adipocytes th
243 demonstrated that increased ACE2 expression exerts protective effects on inflammation in EAU mouse b
247 ase risk may result from regulatory variants exerting their effects only in the presence of immune st
248 tive triphosphate metabolite, Ara-CTP, which exerts antileukemic effects, primarily by inhibiting DNA
250 spermidine extends the lifespan of mice and exerts cardioprotective effects, reducing cardiac hypert
255 ts), or the opposite, when the same molecule exerts adverse effects (the "bad" effects), favouring ca
256 ch as 5-fluorouracil (5-FU) and oxaliplatin, exert such effects, their combination as employed in the
258 nstrates that a Wogonin-rich fraction of SBE exert chondroprotective effects through the suppression
259 domain containing 5 (PRDM5) hypothesized to exert epigenetic effects through histone and DNA methyla
261 ells and must be transported out of cells to exert its effects through activation of 5 specific cell
264 trogens in young, pre-menopausal women could exert paracrine effects through the highly estrogen-resp
265 enetic predispositions to obesity may partly exert their effects through appetitive traits reflecting
266 a majority of disease-associated variants to exert their effects through pancreatic islet dysfunction
267 e ontology analysis revealed that PARP could exert these effects through transcription factors and ch
268 cholerae, and it was previously presumed to exert this effect through regulation of quorum sensing.
269 oward demonstrating that palytoxin congeners exert toxic effects through inhalation both in natural e
270 d discrepancy, PF analysis revealed that FED exerted its effects through multiple JAK2-independent me
271 cessing generates two active fragments, each exerting distinct effects through specific receptors.
275 amic deep brain stimulation in tremor likely exerts its effects through modulation of both olivocereb
277 wever, it remains unknown if hyperosmolality exerts this effect through a central (i.e. CNS) and/or p
282 duction in vivo provides a source of NO that exerts beneficial effects upon the cardiovascular system
285 that a significant fraction of TR variations exert functional effects via alterations of local gene e
287 iotics and other environmental chemicals may exert neurobehavioral effects via disruption of host-ass
289 ment of relapsing multiple sclerosis and may exert therapeutic effects via activation of the nuclear
290 r different EBNAs (EBNA2, -3A, -3B, and -3C) exert unique effects via a single transcription factor,
291 arrest and cardiopulmonary resuscitation by exerting its effect via the perivascular pool of aquapor
292 sults indicate that similar to APC, thrombin exerts cytoprotective effects via beta-arrestin-2 biased
293 drolysis mutants, we show that, although ATP exerts its effects via binding AAA1, ADP effects are med
296 nd integrated quality control mechanism that exerts different effects when invoked to different degre
298 modulate microglia-mediated inflammation and exert neuroprotective effects, with potential for allevi
300 morrhagic stroke outcome, suggesting that it exerts thrombolytic effects without significantly impair
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