ライフサイエンスコーパス: exfoliative toxin

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1 Exfoliative toxin A (ETA) causes staphylococcal scalded

2 Exfoliative toxin A (ETA) is known to be a causative age

3 unctionally address this hypothesis, we used exfoliative toxin A (ETA) to inactivate Dsg1 in Dsg3-/-

4 The crystal structure of exfoliative toxin A (ETA) was reported earlier and shown

5 For these studies, an active recombinant exfoliative toxin A (rETA) was used in a neonatal mouse

6 xic shock syndrome toxin; none had genes for exfoliative toxin A or B.

7 on cleavage of Dsg1 by a bacterial protease, exfoliative toxin A, which removes residues 1 to 381 of

8 lls expressing Delta381-Dsg1 or treated with exfoliative toxin A.

9 one of two Staphylococcus aureus exotoxins, exfoliative toxins A and B (ETA and ETB).

10 -1, staphylococcal enterotoxins A and B, and exfoliative toxin-A, as well as staphylococcal protein A

11 exfoliative toxin to inactivate Dsg1 but not exfoliative toxin alone activate p38, suggesting that p3

12 Exfoliative toxin cannot cleave desmoglein 1 pretreated

13 These data suggest that the specificity of exfoliative toxin cleavage of desmoglein 1 resides not o

14 f two related, but immunologically distinct, exfoliative toxins (ETA and ETB).

15 A resolution crystal structure of the other exfoliative toxin, ETB, which is 40% identical to ETA.

16 The staphylococcal exfoliative toxins (ETs) A and B (ETA and ETB) are 27-kD

17 tively little is known about exactly how the exfoliative toxins (ETs) cause SSSS, much has been disco

18 The exfoliative toxins (ETs) cause staphylococcal scalded sk

19 Exfoliative toxins (ETs) from Staphylococcus aureus blis

20 Both diseases are mediated by exfoliative toxins (ETs), which show exquisite pathologi

21 glein 1 completely inhibited its cleavage by exfoliative toxin, even after calcium was added back.

22 urther our understanding of the mechanism of exfoliative toxin-induced pathology and suggest novel st

23 Here we demonstrate that recombinant exfoliative toxins produced in Escherichia coli do not a

24 dermatitis that results from infection with exfoliative toxin-producing Staphylococcus aureus.

25 The same mAbs plus exfoliative toxin to inactivate Dsg1 but not exfoliative

26 he stratum corneum of skin by elaboration of exfoliative toxin, which hydrolyzes only one peptide bon

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