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1 age signal that make possible the modality's existence.
2 y, metaphorically pulling themselves up into existence.
3 quence analysis approaches will reveal their existence.
4 ds has contributed to skepticism about their existence.
5 ates on the basis of their solitary membrane existence.
6                                          The existence and conservation of such a complex mechanism s
7               However, firm evidence for the existence and functional importance of resident microbio
8 udied during viral infections, whereas their existence and functions in allergic diseases have been s
9 dition to the body of work demonstrating the existence and importance of polyketides in anaerobes, an
10                                          The existence and interaction of proliferating and quiescent
11 eavy elements in the interior, including the existence and mass of Jupiter's core.
12 ates-for the first time to our knowledge-the existence and mechanisms of functional interactions betw
13                           We demonstrate the existence and regulatory divergence of many LORe ohnolog
14                                          The existence and structure of a new class of concentrated m
15                                       The co-existence at the same orbital period of novalike binarie
16 sent convincing experimental evidence of its existence for a charged and massless fermion in an attra
17 l research demonstrates that questioning its existence impacts social behavior.
18                                          Its existence in bulk had never been positively confirmed, d
19 ave been observed in DNA and proteins, their existence in RNA remains an enigma.
20 xo complex but experimental evidence for its existence is still missing.
21  of individual aneuploid CD31(+) CECs and co-existence of "fusion clusters" of endothelial-epithelial
22 at compose it at a local level, supports the existence of "strains" characterized by distinct var gen
23 isual-processing-pathway view by showing the existence of "what" and "where" information in both path
24 lect "what we do with it." Thus, despite the existence of "what" and "where" information in both visu
25 onal symmetry in two dimensions-doubting the existence of 2D crystals-and the first computer simulati
26 th NE and ML differentiation, confirming the existence of a "hybrid" phenotype.
27                    Our results highlight the existence of a clear climate signal in flood observation
28                  Our results demonstrate the existence of a COI1-JAZ2-MYC2,3,4-ANAC19,55,72 module re
29 ral theoretical and empirical work posit the existence of a common magnitude system in the brain.
30 n both enzymes are perturbed, suggesting the existence of a common mechanism for substrate binding an
31                         Our data suggest the existence of a complex regulatory network controlling Lo
32 nger cells are in quiescence, suggesting the existence of a continuum of quiescence depths.
33        These results are consistent with the existence of a cortico-amygdala pathway in humans for pr
34 is pattern of results is consistent with the existence of a cortico-amygdala pathway in humans for pr
35 r morphological characteristics, support the existence of a countercurrent heat exchanger in the head
36                                          The existence of a covalent phosphosugar intermediate provid
37 cas9-containing bacterial genomes for the co-existence of a CRISPR spacer and its target, a potential
38 ion demonstrates three key features: (i) the existence of a critical value of the branching process p
39 with a small isoform of Drosha, implying the existence of a different miRNA processing pathway in the
40                     A new study suggests the existence of a distinct pool of PA in the ER that is req
41                                          The existence of a diverse array of hominins in subequatoria
42              This suggests that, despite the existence of a domain-general processing mechanism (the
43  proteins are over-expressed, suggesting the existence of a feedback circuit to match synaptic protei
44 lation is attenuated by Fxr1, indicating the existence of a feedback loop that contributes to Fxr1 ov
45  the diversity of other tissues-suggests the existence of a functional basis.
46         These results not only establish the existence of a functional, exclusively anaerobic MSP, bu
47 y of these same marker genes, suggesting the existence of a general program in which expression is di
48 eutron reflectivity measurements confirm the existence of a layer with zero net moment only within (0
49                     Our findings support the existence of a long-lived, adaptive NK-cell population m
50 d performs reasonably well in validating the existence of a master regulator when the number of subje
51                                          The existence of a microbial ecosystem associated with the M
52          Instead, the radio data require the existence of a mildly relativistic wide-angle outflow mo
53 cts on behavioral trajectories, implying the existence of a modular temporal program controlled by ne
54                        Our work suggests the existence of a molecular "AND-gate" such that tumor acti
55                                          The existence of a multitude of resistance mechanisms necess
56  a mushy zone with a thickness of 4-8 km.The existence of a mushy zone in the Earth's inner core has
57 or of IFN-gene transcription, suggesting the existence of a negative-feedback regulatory loop that ma
58 havioral domains, to determine the potential existence of a nested structure of factors that underlie
59                             We establish the existence of a non-canonical cortical NOTCH1 signalling
60                     Our findings support the existence of a novel coevolutionary relation between car
61                      Our results unravel the existence of a novel H2S-NO interaction and identify PYK
62                           We demonstrate the existence of a novel mode of quantized vorticity, which
63                  This study demonstrated the existence of a novel population of resident adult cardia
64              These observations indicate the existence of a novel, presently uncharacterized ligand f
65  analysis of signal decay rates suggests the existence of a partially folded p27 intermediate during
66 cific leaf area relationship, we suggest the existence of a photosynthetic stem economic spectrum.
67 anges in extracellular Pi levels implies the existence of a Pi-sensing mechanism that signals to the
68                      Here we demonstrate the existence of a prenatal sub-cortical mechanism that regu
69 ing within seconds [1, 3, 4], suggesting the existence of a rapid mechanism to prevent female rematin
70               Thus, our findings support the existence of a rapid subcortical pathway that is nonsele
71 reduction, microarray analyses suggested the existence of a residual ABA signaling in roots of floode
72                                          The existence of a root/mycorrhizal exudation-hyphal uptake
73     Models of visual attention postulate the existence of a saliency map whose function is to guide a
74  which conferred processivity because of the existence of a second product-binding site.
75  neurophysiological findings may reflect the existence of a sensitive period where the functional con
76                          Here, we report the existence of a sharp genomic transition zone below the p
77 ation of full genomic sequences revealed the existence of a single recombination breakpoint at the bo
78 ized, our work unequivocally establishes the existence of a single-stranded DNA incorporation pathway
79  with the previous serological data show the existence of a sixteenth serovar-designated serovar 16-o
80      In summary, we provide evidence for the existence of a sortable population of multipotent non-ep
81                These results demonstrate the existence of a specific predominant Abeta40 fibril struc
82           Based on these data we suggest the existence of a synaptic activity-mediated neuronal Warbu
83                                          The existence of a thriving peatland at 2700-2150 cal.
84                     Our results indicate the existence of a tipping point.
85                    This finding supports the existence of a truncated ZSWIM6 protein lacking the Sin3
86 d of patients are both signal flares for the existence of a tumor and harbingers of metastasis.
87  BaFe 2(As0.67P0.33)2 films, and propose the existence of a universal minimum realizable S approximat
88    The two-electrode sensor can identify the existence of a variety of heavy metals in drinking water
89  to prevent tumor recurrence, suggesting the existence of a vismodegib-resistant reservoir of tumor-p
90 ry of the Asterids, further establishing the existence of a whole-genome triplication at the base of
91 tors, supporting the previously hypothesized existence of a WRKY subregulatory network.
92 rough ZapB and raises the possibility of the existence of additional divisome proteins that also func
93 l primary lymphedema cases, underscoring the existence of additional genetic factors.
94  score and heritability analyses suggest the existence of additional genetic modifiers, supporting ex
95 er GR recognition sequences, arguing for the existence of additional mechanisms that interfere with G
96 typic variation within disorders implies the existence of additional modifying factors in pathways th
97 MglA localizes symmetrically, suggesting the existence of additional regulators that control moving d
98                   We further demonstrate the existence of adiabatic pumping for each phase and gain a
99 e-dependent manner and clearly indicated the existence of age-related glycation hot spots in the plan
100              Sanger sequencing confirmed the existence of all novel rare BDNF variants.
101 ition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA repl
102  idea that high genetic diversity and/or the existence of alternative strategies in polymorphic speci
103            Our results suggest the potential existence of an additional binding site and provide new
104 milar to MMR-bearing species, suggesting the existence of an alternative to the canonical MutS-MutL-b
105 veal that persistence of BMP alterations and existence of an autocrine loop promote CML-primitive cel
106                    These results suggest the existence of an efficient regulatory neural mechanism th
107                         Our data support the existence of an endothelial KATP channel that contains K
108                  This study demonstrates the existence of an immune-mediated ET-1 production induced
109                              To evaluate the existence of an interaction between wine proteins and et
110                                          The existence of an intermediate-mass black hole in the cent
111 gene families in higher plants points to the existence of an intriguing regulatory network and poses
112 nt analytical and numerical evidence for the existence of an inverse energy cascade in an experimenta
113 aurs than previously thought and suggest the existence of an optimal ecomorphology for short-necked p
114 tives and training processes for CHWs, (iii) existence of an organizational structure dedicated to co
115        In summary, our work demonstrates the existence of an underappreciated healthcare-associated e
116         Its linear organization suggests the existence of an underlying chromosomal axis that serves
117                 Here, the authors unveil the existence of another type of quasiparticle, bielectron v
118 was to determine the prognostic impact of co-existence of APC and PIK3CA mutations in patients underg
119 terodimerizes with other GPCRs; however, the existence of APJ homodimers and oligomers remains to be
120 e principle of cognition could amount to the existence of appropriate rules governing self-organizati
121 te evidence from neuroscience supporting the existence of at least partly distinct neuronal substrate
122 quinone (ASQ) is not sufficient to infer the existence of bifurcating activity, although such a speci
123 ted funding for ZIKV research; (2) the prior existence of both flavivirologists and maternal-child he
124 behavior and plasma osmolality points to the existence of brain networks that integrate exterosensory
125 trical and elastic parameters that allow the existence of bubble domains.
126 wn subdivisions within the EP and reveal the existence of cascading, molecularly distinct projections
127                                          The existence of catalytic antibodies has been known for dec
128                 In addition, we detected the existence of CD73 and ecto-AMPase activity in the nocice
129                      However, in plants, the existence of cell walls, subcellular organelles and the
130 the low field region are consistent with the existence of chiral ordering in a temperature range abov
131  continuous thickening regime, we report the existence of clearly defined dynamic localized regions o
132                      Our study suggested the existence of common regulatory mechanisms shared by GSs
133 rity of patients fail to respond, suggesting existence of complementary immune evasion mechanisms.
134 ecords and geodynamic modelling indicate the existence of complex interactions between glacial sea le
135 fluence on interface dynamics, leading to co-existence of concave and convex interfaces.
136 ces are partly, but not entirely, due to the existence of concomitant predation.
137 iation but not self-renewal and suggests the existence of context-specific H3K4 methylation that regu
138 er, despite the use of inert electrodes, the existence of corrosion was not evaluated, being an impor
139                     Here, we demonstrate the existence of cross-seeding as a crucial step in the form
140 plain properties of the universe such as the existence of dark matter, the amount of dark energy, and
141             These findings point towards the existence of defined molecular mechanisms underlying var
142                The challenge arises from the existence of different competitive pathways.
143 lar mass distribution (MMD) and the presumed existence of different end group functionalities as well
144        A great body of evidence unveiled the existence of different stem cell types in various tissue
145                                 However, the existence of diphosphorylated RNA in bacteria has never
146 ponders to viral infection and highlight the existence of distinct innate immune programs in astrocyt
147 rines from the Early Cretaceous suggests the existence of diverse Agaricomycetes and a specialized tr
148                                          The existence of DMN correlates in other species, such as mi
149 act of somatic L1 insertions in neurons, the existence of donor L1s that are highly active ('hot') in
150 e conclude that there is no evidence for the existence of Drosophila courtship song rhythms.
151 ess than half a day), which may indicate the existence of Earth-mass and super-Earth-mass free-floati
152  of genetic structure of Northern Eurasians, existence of East-West and North-South genetic gradients
153             Overall, our results suggest the existence of evolutionarily conserved pathways used by S
154              Calculations further proved the existence of exchange coupling among the paramagnetic ce
155 ium emergent states evolve with a complex co-existence of excitons, carriers and phonons, where a del
156                      First, we establish the existence of exclusively surface-dominated transport via
157             Specifically, we demonstrate the existence of Ferrell-Berreman (FB) modes within frequenc
158                                          The existence of fine-grain climate heterogeneity has prompt
159                   We provide evidence of the existence of free methylated nucleotides capable of dist
160                                          The existence of frequent jumps in a motion that is otherwis
161 o be functionally independent because of the existence of functional mini-inteins without HEN domains
162 however, there is ambiguous evidence for the existence of g when analyzing data using a mixed approac
163               Phylogenomics has revealed the existence of genes conserved for AM symbiosis, providing
164  structural brain defects, and the potential existence of genotype-phenotype correlations, all of whi
165 blue phases, which have been hindered by the existence of grain boundaries.
166               The major issue stems from the existence of higher-energy Zundel isomers of this cluste
167 ing-probe-microscopy results demonstrate the existence of highly conductive regions (tens of nanomete
168 he underlying mechanisms remain unclear, the existence of highly specific alloreactive TCRs has led t
169                                          The existence of HIV reservoirs in infected individuals unde
170                            For instance, the existence of hydroxylated CTTs (OH-CTTs) in authentic en
171 S) have repeatedly provoked dismissal of the existence of immune privilege of the CNS.
172 cribed and quantified for the first time the existence of individual aneuploid CD31(+) CECs and co-ex
173                                 However, the existence of intermediate-mass black holes is still unce
174                                          The existence of lacrimal gland stem/progenitor cells was pr
175 ts high piezoelectricity originates from the existence of large fluctuations of polarization in the o
176 ch of the ANPS, this study: (i) examined the existence of latent personality profiles, (ii) studied t
177  virus despite decades of therapy due to the existence of latent reservoirs of integrated HIV-1, whic
178 nterface between the film and substrate, the existence of Lix Fe3 O4 rock-salt phase during lithiatio
179                                              Existence of localized clusters with opposing trend to t
180  subset of atomic insulators, defined by the existence of localized symmetric Wannier functions.
181                                          The existence of long-lived reservoirs of latently infected
182 , such as when walking on sand, suggests the existence of long-term motor memories.
183 lectron microscopy (EM), we characterize the existence of LVPs that cofractionate with lipoproteins,
184 a M. smegmatis surrogate model, suggests the existence of M. tuberculosis mutator strains.
185 ed accretion mode, which in turn implies the existence of magnetically gated accretion, in which disk
186                                          The existence of massive (10(11) solar masses) elliptical ga
187 rom ten to hundreds of genes, suggesting the existence of master genetic regulators.
188 to two real datasets, our method ensures the existence of master regulators and identifies biological
189                          Here, we report the existence of meningeal lymphatic vessels in human and no
190  These results bring strong evidence for the existence of mGlu2-4 heterodimers in native cells.
191    An important feature of birnessite is the existence of Mn(III) within the MnO2 layers, accompanied
192 y, and live-cell imaging, we demonstrate the existence of mobile COPII-coated vesicles that completel
193                                          The existence of mobile ions in the oxide semiconductors cou
194 rmitian systems that allow, for example, the existence of modes with real propagation constants, for
195 s the phenomenon of polyamorphism (i.e., the existence of more than one disordered solid state), emph
196 tric spaces play a key role in dictating the existence of multi-fractal scaling and (ii) the multi-fr
197                                          The existence of multipartite viruses is an intriguing myste
198  products, Hans Krebs first demonstrated the existence of multiple glutaminases in mammals.
199                    Our workflow suggests the existence of multiple stable Golgi organizational states
200 herpesvirus (KSHV) genome and postulated the existence of multiple viral long noncoding RNAs (lncRNAs
201 terized, accumulating evidence points to the existence of multiple, less well-defined layers of regul
202                          We also predict the existence of Na2HeO with a similar structure at pressure
203       Collectively, our data rationalize the existence of naturally occurring RG4-assembling tRNA fra
204                        Our data point to the existence of negative feedback loops between these two r
205 SIGNIFICANCE STATEMENT: Here we test for the existence of neural tuning to numerosity in the developi
206  highly G-rich sequence and demonstrates the existence of non-canonical G4s in cells, thus broadening
207    These results indicate the possibility of existence of nonmagnetic Co in the earth's core under hi
208            Overall, the study highlights the existence of novel regulatory mechanisms between Id1/PGC
209              Despite this importance and the existence of NS5B crystal structures, our understanding
210 port transport measurements that suggest the existence of one-dimensional chiral Majorana fermion mod
211   This complex gap configuration reveals the existence of orbital-selective Cooper pairing that, in F
212 carboxylated osteocalcin changes, suggesting existence of other osteokines that are under the control
213 nial stratification of the south arm and the existence of oxic shallow brine and anoxic deep brine la
214  soluble and thus easy to process due to the existence of oxygen containing groups.
215 delayed but can be completed, suggesting the existence of parallel membrane-reorganizing pathways tha
216 vices it provides people rather than for the existence of particular species.
217 ependent dosage compensation, suggesting the existence of pathways excluding specific loci from dosag
218                Our data directly confirm the existence of polarity at the twin boundaries, and demons
219                            This suggests the existence of polycarboxylated aromatic and condensed aro
220                              To document the existence of primary pancreatic secretinoma in patients
221  distance, the factor allowed predicting the existence of projections with very high accuracy.
222 enomic mapping by providing evidence for the existence of proteins predicted at the genomic level.
223 ved (2.0 x 10(10) M(-1) s(-1)), implying the existence of proton collecting antennae for expedited pr
224      Using this new tool, we demonstrate the existence of putative auxin binding sites in the cell wa
225 leus and solitary tract, consistent with the existence of PVHCrh-dependent behavioral pathways.
226                                          The existence of quantized vorticity in bosonic systems stim
227                   This was attributed to the existence of regions depleted by aggregates of certain s
228       In the present study, we highlight the existence of resident gammadelta T cells in the SLOs of
229 in preclinical trials and have suggested the existence of resistance mechanisms with the need to iden
230                   These findings suggest the existence of RNA-guided transposition and fit the guns-f
231  field (SEF) of other primates, suggests the existence of SEF in galagos.
232 s, and they show striking parallels with the existence of sensitive developmental periods and the cum
233 y low frequency in the blood, suggesting the existence of separate compartments of T cells in both tu
234  stability of the 9R phase is related to the existence of sessile Frank loops.
235 ropean anchovy (Engraulis encrasicolus), the existence of several populations has been proposed but a
236 hifting social conditions affect the form or existence of shamanism.
237                    These results support the existence of short-range CDW correlations above TC in un
238                          Theory suggests the existence of slow reservoir temporarily emptied by stimu
239  Although recent evidence has pointed to the existence of small open reading frame (smORF)-encoded mi
240 es from previous models that assume only the existence of small, uniformly magnetized particles, wher
241 (64)Cu(II) was reduced to (64)Cu(I) with the existence of sodium L-ascorbate, DL-Dithiothreitol or cy
242  insight into viral quasispecies and the pre-existence of some drug-resistant variants in the liver,
243 e specification, our results demonstrate the existence of some key differences in lineage specificati
244                 The diagram also reveals the existence of special points at which minor changes in si
245                                          The existence of specific polymorphisms in genes of key horm
246      Together, these results demonstrate the existence of specific, reproducible transcriptomic compo
247  have been hypothesized to be enabled by the existence of stable associates between Gi/o proteins and
248  large in the InGaN DA structure despite the existence of strain effect and build-in polarization fie
249                                          The existence of strata devoid of mating-type genes, despite
250               Network analysis suggested the existence of strong relationships among specific fungal
251 tential coexistence of multiple populations, existence of substantial diversity, and similarity of ho
252                     This finding implies the existence of substantial ice volume in the Aurora subgla
253                                  To test the existence of subtype-specific prognostic genes for non-s
254          Although some evidence supports the existence of such a functional gradient, other studies a
255 discrepant results in support or against the existence of such binding mode in solution.
256                                          The existence of such dual route supports recent theoretical
257                                    It is the existence of such modes which is responsible for the won
258 romatin modifier combinations, revealing the existence of synergistic as well as adverse effects of c
259                   Our model demonstrates the existence of temporal efficiencies in conservation manag
260 copy and theoretical studies demonstrate the existence of the (HCOO(-))(H2SO4) pair at an energy slig
261                                          The existence of the dihydrogen complexes, as well as isotop
262                       Here, we challenge the existence of the idea of noninfectious sepsis given that
263                                 Although the existence of the NF4(+) cation has been known for 51 yea
264                                          The existence of the oft-invoked intermediates containing th
265 ns disagree about the depth, origin and even existence of the respired carbon pool.
266                                          The existence of the Sun's hot atmosphere and the solar wind
267 ned from these disorders, we rationalize the existence of these diseases in the context of evolution,
268 tantial body of research has established the existence of these patterns in diverse systems, rigorous
269 tions, review the available evidence for the existence of these populations in the kidney, and discus
270                                          The existence of this relationship suggests that predictions
271                                          The existence of this supermassive black hole when the Unive
272 g roles during autophagy, and illustrate the existence of tight mechanistic links between the cellula
273                                          The existence of tightly-integrated cross-talk through multi
274 g aspect of developmental programming is the existence of transgenerational effects that influence of
275 d other forms of cancer.(1-4) The nature and existence of tumor-initiating cells for leukemia and oth
276                    In support, we reveal the existence of two biochemically distinct DAXX-containing
277                  We present evidence for the existence of two different reaction pathways for H3(+) f
278                              We discover the existence of two dissipative states.
279 arance, i.e. the body image, and suggest the existence of two functionally separate representations o
280                      These data indicate the existence of two separate pathways from the LHb to the V
281                       We have discovered the existence of ultrathin superdense nonmagnetic cobalt lay
282 ifier known has been the Star graph, and the existence of undirected graphs with stronger amplificati
283                    These results suggest the existence of variations, such as ethnic differences, in
284                                  Despite the existence of various models for optimally integrating re
285                       The model predicts the existence of VEGF threshold in ERK1/2 activation that ca
286 ay photoelectron spectroscopy, and prove the existence of vertical dipoles by second harmonic generat
287 ra of superlattices, we also investigate the existence of wave effects.
288 d by robot-enhanced AFM, can help reveal the existence of weak stabilizing interactions between the d
289 e OPA5 locus on chromosome 19q12.1-13.1, the existence of which is denied by the present study.
290 icken embryo as a whole, we interrogated the existence or absence of genomic imprinting in the 12-day
291      However, there are very few data on the existence or nature and timeline of such reorganization
292 and glacial-interglacial timescales, but its existence over the most recent past remains unclear.
293                                Despite their existence, rarely does a method consider the well-known
294              Its ability to present phase co-existence separated by domain walls (DWs) above room tem
295                           Soils underpin our existence through food production and represent the larg
296 ments on muscle, decades passed before their existence was accepted.
297 as been an enigmatic molecule ever since its existence was first hypothesized.
298                    These findings reveal the existence within different tissues of an amplification s
299                       Our results reveal the existence, within mitochondria, of different cAMP-Epac1
300                                 This nomadic existence would allow them to accomplish their surveying

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