ライフサイエンスコーパス: exocrine

1 , inhibiting progenitor differentiation into exocrine acinar and endocrine islet cells.

2 t beta-catenin is required qualitatively for exocrine acinar but not endocrine development, precisely

3 oform blocked the irreversible transition of exocrine acinar cells into pancreatic preneoplastic duct

4 and (4) aberrantly differentiated endocrine exocrine (ADEX) that correlate with histopathological ch

5 s of Prox1 from the pancreas led to multiple exocrine alterations, most notably premature acinar cell

6 We found that, compared with exocrine and beta cells, differentiated alpha cells exhi

7 which are aliphatic amines, are reported in exocrine and endocrine cells, with insulin-producing bet

8 ed in the nuclear/perinuclear region of both exocrine and endocrine compartments.

9 ong-term survival, quality-of-life pain, and exocrine and endocrine function.

10 d vertebrates, is a compound organ with both exocrine and endocrine functions.

11 llow-up of 36 months, the rates of new-onset exocrine and endocrine insufficiency were 6%and 2%, resp

12 Pancreatic exocrine and endocrine lineages arise from multipotent p

13 radiographs did not discriminate between the exocrine and endocrine pancreas in control animals, wher

14 e profound morphological changes in both the exocrine and endocrine pancreas.

15 humans resulted in a marked expansion of the exocrine and endocrine pancreatic compartments, the form

16 acinar-specific CEL-MUT protein causes both exocrine and endocrine pancreatic disease.

17 mild exocrine pancreas disease, progressive exocrine and endocrine pancreatic loss during the first

18 Exocrine and endocrine pancreatic secretions are regulat

19 letion attenuated the loss of PERK-deficient exocrine and endocrine pancreatic tissues and prevented

20 terature regarding the regulation of gastric exocrine and endocrine secretion, both basic science and

21 rmones and neural inputs regulate pancreatic exocrine and endocrine secretion.

22 ficient embryonic pancreas, defects occur in exocrine and endocrine tissues shortly after differentia

23 epitracheal glands, for which a double role (exocrine and endocrine) has been demonstrated, are exami

24 an indispensible role in the development of exocrine and ocular surface disease in Aire knockout mic

25 he presence of periepithelial infiltrates in exocrine and parenchymal organs or resulting from immuno

26 Metformin decreased pancreatic exocrine and trended to decrease endocrine apoptosis in

27 oride channel (CaCC) important for neuronal, exocrine, and smooth muscle functions.

28 when administered concurrently, and reduces exocrine apoptosis (reducing the impact on potential isl

29 n-4 led to acceleration of the disruption of exocrine architecture and chronic pancreatitis with muci

30 ibed in the literature, with an incidence of exocrine atrophy/inflammation seen in S-D (42-72%), HIP

31 ocrine prostate cancer cells, and MDA-MB-231 exocrine breast cancer cells.

32 l that central D2Rs mediate a neuroendocrine-exocrine cascade that controls the maturation of the GH

33 Using these reagents, the timing of exocrine cell fate commitment in the developing pancreas

34 eas development is critical to endocrine and exocrine cell fate.

35 m cells gives rise to separate endocrine and exocrine cell lineages.

36 the 52-week study showed an increase in the exocrine cell mass in liraglutide-dosed animals, with no

37 also increases beta-cell replication but not exocrine cell or hepatocyte replication.

38 Pancreatic exocrine cell plasticity can be observed during developm

39 d with incretin therapy, with both increased exocrine cell proliferation (P < 0.0001) and dysplasia (

40 4 may play a role in the efflux of cAMP from exocrine cells and neurokinin receptors are important in

41 acute inflammatory stress by locking damaged exocrine cells in a permanently de-differentiated state.

42 The endocrine and exocrine cells in the adult pancreas are not static, but

43 Reprogramming of pancreatic exocrine cells into cells resembling beta cells may prov

44 We propose that the lysosomal defect in the exocrine cells is caused by the combination of increased

45 he nongenetic conversion of human pancreatic exocrine cells to endocrine cells is novel and represent

46 development, in the progression from normal exocrine cells to metastatic PDA.

47 ss and increase susceptibility of pancreatic exocrine cells to other metabolic stressors.

48 In the exocrine cells, a rapid efflux of radioactivity was obse

49 protein content), as well as degeneration of exocrine cells, decreased zymogen granules, and alterati

50 (INS-1 and human islets), but not PANC1 and exocrine cells, was mediated specifically by intracellul

51 ndscape of human pancreatic alpha, beta, and exocrine cells.

52 soforms play a regulatory role in pancreatic exocrine cells.

53 ha, 105 beta, 6 delta endocrine cells and 47 exocrine cells.

54 ntling of the secretory apparatus of diverse exocrine cells.

55 ls, with normal composition of endocrine and exocrine cellular compartments.

56 lear form of Yap are apparent throughout the exocrine compartment and correlate with increases in lev

57 The exocrine compartment makes and secretes digestive enzyme

58 The exocrine compartment of mutant mice was hypoplastic and

59 No changes were seen in the exocrine compartment of the pancreas, and the mice had o

60 s1 leads to the impaired regeneration of the exocrine compartment, accelerated fatty metaplasia, and

61 n show elevated levels of CD8 T cells in the exocrine compartment.

62 ptophysin dual positive cells arise from the exocrine compartment.

63 of endocrine genes including insulin in the exocrine compartment.

64 ontent or the number of Ki67(+) cells in the exocrine compartment; however, pancreatic protein conten

65 blocked differentiation of the endocrine and exocrine compartments, whereas loss of a single Yap alle

66 0 putative glandular structures, and for the exocrine component of the epitracheal glands.

67 We found that serpin B13 is expressed in the exocrine component of the mouse pancreas, including the

68 The exocrine congenital defects of Prox1(DeltaPanc) pancreat

69 rom beta-cell injury due in part to pancreas exocrine damage and lipofibrosis.

70 Along with exocrine defects, including impaired acinar cell maturat

71 reatic findings in all groups included focal exocrine degeneration, atrophy, inflammation, ductular c

72 rox1 as an important regulator of pancreatic exocrine development.

73 and disruptions in pancreatic branching and exocrine differentiation.

74 , enable vascular cross-clamping, and create exocrine drainage into the jejunum.

75 Bladder exocrine drainage was associated with higher risk of inf

76 ators Neurog3, MafA, Pdx1 and Pax6 converted exocrine duct cells into endocrine progeny with hallmark

77 hat regulate ELS formation and their role in exocrine dysfunction and autoimmunity in SS.

78 a monogenic form of diabetes and pancreatic exocrine dysfunction due to mutations in the CEL gene en

79 hat trigger ELS formation, autoimmunity, and exocrine dysfunction in SS are largely unknown.

80 the exocrine pancreas and, in the context of exocrine dysplasia, may accelerate formation of neoplast

81 minations and quantifications indicated that exocrine, endocrine and ductal compartments retained the

82 ield strength has yet to fully visualize the exocrine, endocrine, vascular, and stromal components of

83 The exocrine-enriched cells rapidly dedifferentiated in cult

84 his study was to determine whether the human exocrine-enriched fraction from the islet isolation proc

85 In conclusion, reprogramming of human exocrine-enriched tissue can be best achieved using fres

86 functions (including water/salt homeostasis, exocrine fluid secretion, and epidermal hydration) and h

87 per gram at 15 min), most likely due to the exocrine function and high protein turnover within the p

88 rfusion, injury, as measured by amylase, and exocrine function of human pancreases using EVNP and dem

89 , quality of life [QoL]), medical (endo- and exocrine function), and clinical (reoperation) results r

90 lop a noninvasive imaging test of pancreatic exocrine function.

91 ic tissue with differentiated morphology and exocrine function.

92 noninvasive method for assessing pancreatic exocrine function.

93 pment and support a rationale for performing exocrine functional tests for patients with IRF6-damagin

94 nced by preservation of pancreatic endocrine/exocrine functions and a low rate of reoperation for tum

95 w-up of 50 months, both pancreatic endocrine/exocrine functions were preserved in 92% of patients.

96 nvolved in the generation and maintenance of exocrine gland acinar cells have not yet been establishe

97 Although IgG autoantibodies against various exocrine gland antigens have been described in IgG4-RD,

98 , exhibited extensive vacuolization of their exocrine gland cells, while the liver, brain, and muscle

99 ion, our data report a novel role of Irf6 in exocrine gland development and support a rationale for p

100 ver 3 wk post-AdV infection, consistent with exocrine gland dysfunction as a consequence of the infla

101 lling, smooth muscle contraction, airway and exocrine gland secretion, and rhythmic movements of the

102 S. invicta venom, N. fulva applies abdominal exocrine gland secretions to its cuticle.

103 Characterizations of the myriad neuropteran exocrine gland systems, including prothoracic, metathora

104 s similar to CpMRP and assume therefore that exocrine gland-based defensive strategies, evolved by th

105 defined circuit by which a single compound, exocrine gland-secreted peptide-1 (ESP1), enhances repro

106 roduced by young mice before puberty, termed exocrine-gland secreting peptide 22 (ESP22).

107 The morphology of 21 exocrine glands and 13 supposedly exocrine structures re

108 helial mononuclear cell infiltrates, both in exocrine glands and in other parenchymal organs (kidney,

109 We demonstrate that the vacuoles in the exocrine glands are enlarged autolysosomes containing un

110 likely calcium-dependent chloride channel of exocrine glands has led to a more detailed understanding

111 HAT-L4 was expressed in epithelial cells and exocrine glands in tissues including skin, esophagus, tr

112 nifesting as lymphocytic infiltration of the exocrine glands leading to chronically impaired lacrimal

113 thological findings were observed in several exocrine glands of patients with mucolipidosis II.

114 oimmune disease involving salivary and other exocrine glands that leads to progressive lymphocytic in

115 lymphocytic infiltration and destruction of exocrine glands, followed by systemic organ damage and B

116 characterized by lymphocytic infiltration of exocrine glands, mainly salivary and lacrimal, resulting

117 identify the role of IRF6 in development of exocrine glands, specifically the major salivary glands.

118 ch as the secretions of airway epithelia and exocrine glands, the contraction of smooth muscles, and

119 c autoimmune disorder that typically affects exocrine glands--mainly labial and lacrimal--leading to

120 ent of salivary glands and potentially other exocrine glands.

121 e (SjS), an autoimmune disease targeting the exocrine glands.

122 ized by diminished secretory function of the exocrine glands.

123 secretion is utilized by epithelial cells of exocrine glands.

124 by a progressive chronic attack against the exocrine glands.

125 eaf clipping, and application of fluids from exocrine glands.

126 ke peptide 1 (GLP-1) receptor agonist, is an exocrine hormone, which has potent insulinotropic action

127 The exocrine human pancreas carcinoma cell line (PANC-1) and

128 Pancreatic exocrine insufficiency (PEI) reduces pancreatic secretio

129 left-sided resection, the risk of developing exocrine insufficiency after surgery was higher after dr

130 Subclinical exocrine insufficiency was demonstrated by low fecal ela

131 fficiency was present in 57% of patients and exocrine insufficiency was present in 77%.

132 adult-onset diabetes, with subclinical or no exocrine insufficiency, suggesting an important role for

133 or childhood-onset diabetes with or without exocrine insufficiency.

134 evention and control of diabetes and perhaps exocrine insufficiency.

135 adult-onset diabetes with subclinical or no exocrine insufficiency.

136 apillaries were, however, found at the islet-exocrine interface, frequently located along blood capil

137 ted in the insulitic lesion in the endocrine-exocrine interface.

138 trates, independently of the severity of the exocrine lesion and in the absence of amyloid deposits.

139 DA subtypes: classical, quasimesenchymal and exocrine-like, and we present evidence for clinical outc

140 ination to inactivate Pdx1 in the pancreatic exocrine lineage during embryonic stages.

141 st that POSTN is a crucial factor for proper exocrine lineage-specific regeneration after severe acut

142 te to cells within the pancreatic ductal and exocrine lineages.

143 s were located in fibrotic septa between the exocrine lobules and adjacent to the ductal system of th

144 stinct from the actin web that surrounds the exocrine lumen.

145 gulate networks involved in KRAS activation, exocrine (NR5A2 and RBPJL), and endocrine differentiatio

146 MNH is emitted from exocrine opisthonotal oil glands, which are potent organ

147 ations such as pancreaticocutaneous fistula, exocrine or endocrine pancreatic insufficiency, need for

148 To study recovery from ER stress in the exocrine organ, we generated mice with conditional disru

149 essential role in the secretory function of exocrine organs.

150 lated rapidly in both endocrine CM cells and exocrine PANC-1 cells.

151 Bmi1 contributes to regeneration of the exocrine pancreas after cerulein-induced injury through

152 inhibition of polyamine biosynthesis reduces exocrine pancreas and beta cell mass, and that these red

153 s a lethal autoimmune syndrome involving the exocrine pancreas and other abdominal organs.

154 herapy may induce focal proliferation in the exocrine pancreas and, in the context of exocrine dyspla

155 Diseases of the exocrine pancreas are often associated with perturbed di

156 3 (ST3, matrix metalloproteinase 11) in the exocrine pancreas at metamorphic climax.

157 A genuine understanding of human exocrine pancreas biology and pathobiology has been hamp

158 The exocrine pancreas can give rise to endocrine insulin-pro

159 The exocrine pancreas can undergo acinar-to-ductal metaplasi

160 Expression of the homeobox gene Prox1 in the exocrine pancreas changes throughout development in mice

161 The majority of the exocrine pancreas consists of the secretory acinar cells

162 and that maintained ductal fluid flow in the exocrine pancreas could delay the onset of CFRD.

163 Ptf1a is a gene required for exocrine pancreas development and is first expressed as

164 were required for pancreatic viability; the exocrine pancreas died in mice that were depleted of DCs

165 netic factors likely influence the extent of exocrine pancreas disease in CF ferrets and have implica

166 Interestingly, prior to major exocrine pancreas disease, CF kits demonstrated signific

167 Although CF kits are born with only mild exocrine pancreas disease, progressive exocrine and endo

168 the needed capacity for organ recovery from exocrine pancreas disease.

169 raumatic brain injury or cardiac arrest; and exocrine pancreas DNA was identified in patients with pa

170 Bmi1 expression was up-regulated in the exocrine pancreas during regeneration after cerulein-ind

171 eatorrhea was induced by embolization of the exocrine pancreas gland and pancreatic duct ligation in

172 ated the role of Prox1 in development of the exocrine pancreas in mice.

173 sizes an underappreciated involvement of the exocrine pancreas in the natural course of type 1 diabet

174 cer (11)C-hydroxytryptophan in endocrine and exocrine pancreas in vitro and in vivo.

175 The pancreatic anlage that gives rise to the exocrine pancreas is located in the ventral gut endoderm

176 The exocrine pancreas of adult mice can be remodeled by re-e

177 y, we report that CD8 T cells infiltrate the exocrine pancreas of diabetic subjects in high numbers a

178 copy and immunohistochemical analysis in the exocrine pancreas of multiorgan donors with T1D (both at

179 the effects of exenatide (EXE) treatment on exocrine pancreas of nonhuman primates.

180 the effects of constitutive ER stress in the exocrine pancreas of these mice.

181 The exocrine pancreas plays an important role in endogenous

182 After metamorphosis is complete the exocrine pancreas redifferentiates in the growing frog f

183 The liver and exocrine pancreas share a common structure, with functio

184 lete neoplastic transformation of the entire exocrine pancreas shortly after birth.

185 ounts and chemotaxis as well as a diminished exocrine pancreas size in a SRP54-knockdown zebrafish mo

186 Most importantly, the increase in exocrine pancreas size, protein/DNA content, and acinar

187 ctrum of fibro-inflammatory disorders of the exocrine pancreas that includes calcifying, obstructive,

188 on and pancreatitis, and inflammation of the exocrine pancreas that promotes development of pancreati

189 ancreatitis is a debilitating disease of the exocrine pancreas that, under chronic conditions, is a m

190 n order to reveal a possible requirement for exocrine pancreas tissue in endocrine development and/or

191 Endocrine and exocrine pancreas tissues are both derived from the post

192 that actin-coated secretory vesicles of the exocrine pancreas travel this distance over bundles of s

193 istorically, diabetes due to diseases of the exocrine pancreas was described as pancreatogenic or pan

194 cute inflammatory phase, the recovery of the exocrine pancreas was massively impaired in Postn-defici

195 of Bmi1(-/-) mice were hypoplastic, and the exocrine pancreas was replaced with ductal metaplasia th

196 ities, including extensive fibrosis, loss of exocrine pancreas, and islet disorganization.

197 eatment did not exert any negative effect on exocrine pancreas, by inducing either pancreatic inflamm

198 itis is caused by inflammatory injury to the exocrine pancreas, from which both humans and animal mod

199 in cey mutants, including HSPCs, the retina, exocrine pancreas, intestine, and jaw cartilage.

200 They are deeply embedded in the exocrine pancreas, limiting their accessibility for func

201 r tissues, including the heart, vasculature, exocrine pancreas, liver, and central nervous system.

202 P) is a painful inflammatory disorder of the exocrine pancreas, ranking as the most common gastrointe

203 This reduces enzyme production by the exocrine pancreas, resulting in digestive insufficiencie

204 activity and duct cells within the liver and exocrine pancreas, whereas hepatocyte and acinar pancrea

205 Progression of diseases of the exocrine pancreas, which include pancreatitis and cancer

206 atic capillaries were regularly found in the exocrine pancreas, with small lymphatic vessels located

207 on factor 1-L complex (PTF1-L) in regulating exocrine pancreas-specific gene expression.

208 Exocrine pancreas-specific overexpression of CN inhibito

209 Thus, LRH-1 is a key regulator of the exocrine pancreas-specific transcriptional network requi

210 nd complete neoplastic transformation of the exocrine pancreas.

211 ntracellular cyclic AMP (cAMP) levels in the exocrine pancreas.

212 atic progenitors and derived lineages of the exocrine pancreas.

213 stigated the role of Bmi1 in regeneration of exocrine pancreas.

214 receptor liver receptor homolog-1 (LRH-1) in exocrine pancreas.

215 evention of alcohol-induced ER stress in the exocrine pancreas.

216 for the injurious effects of low pHe on the exocrine pancreas.

217 vely active form of the GTPase, Kras, in the exocrine pancreas.

218 (ER) is abundant in the acinar cells of the exocrine pancreas.

219 nse hyperactivation and tissue injury of the exocrine pancreas.

220 of other diseases, including diseases of the exocrine pancreas.

221 that is distinct from those that inhabit the exocrine pancreas.

222 s that are scattered unevenly throughout the exocrine pancreas.

223 the pancreatic islets while being absent in exocrine pancreas.

224 CACs are a functional component of the exocrine pancreas; however, our fate-mapping results ind

225 IL-1betaAb treatment also protected the exocrine pancreas; the number of infiltrating macrophage

226 and KCR8-16 mice developed dedifferentiated exocrine pancreata within 2 months of age and became mal

227 Thus, in exocrine pancreata, Grp78 heterozygosity regulates ER ch

228 NETs) derived from the staging algorithm for exocrine pancreatic adenocarcinomas.

229 ficient hESCs and iPSCs manifest deficits in exocrine pancreatic and hematopoietic differentiation in

230 e of 51 y at baseline were included, and 865 exocrine pancreatic cancers were diagnosed after a media

231 yptophan is trapped in beta-cells but not in exocrine pancreatic cells.

232 imilar to those in people with CF, including exocrine pancreatic destruction, focal biliary cirrhosis

233 noreactive trypsinogen (IRT), a biomarker of exocrine pancreatic disease in cystic fibrosis (CF), is

234 le entity; it occurs because of a variety of exocrine pancreatic diseases with varying mechanisms of

235 , autophagy, and obesity interact to promote exocrine pancreatic disorders.

236 e first 2 months of life with no evidence of exocrine pancreatic dysfunction and a morphologically no

237 zed by bone marrow failure with neutropenia, exocrine pancreatic dysfunction and skeletal abnormaliti

238 autosomal dominantly inherited diabetes and exocrine pancreatic dysfunction.

239 S) is the second leading cause of hereditary exocrine pancreatic dysfunction.

240 No correlation between endocrine or exocrine pancreatic function and pain was found, whereas

241 pitfalls in the use of diagnostic tests for exocrine pancreatic insufficiency (EPI) confound interpr

242 utosomal-recessive disorder characterized by exocrine pancreatic insufficiency and hematopoietic dysf

243 s with insulin-treated neonatal diabetes and exocrine pancreatic insufficiency requiring enzyme repla

244 Two of the four patients had exocrine pancreatic insufficiency requiring replacement

245 ve ribosome assembly and are associated with exocrine pancreatic insufficiency, chronic neutropenia a

246 We observed endocrine/exocrine pancreatic insufficiency, which had not previou

247 s primarily characterized by neutropenia and exocrine pancreatic insufficiency.

248 Patients who underwent surgery for exocrine pancreatic malignancy with curative intent were

249 Secretin is a hormone that stimulates the exocrine pancreatic secretion of bicarbonate-rich fluid

250 evidence to support a causal contribution of exocrine pancreatic status on CFRD risk.

251 T cell-specific loss of Foxo1 resulted in exocrine pancreatitis, hind limb paralysis, multiorgan l

252 fat infiltration (P < 0.05) was noted in the exocrine parenchyma of IL-1betaAb-treated CDs-HSD rats c

253 ed detection in the clinic for endocrine and exocrine pathologies.

254 GATA4 gene who have diabetes and a variable exocrine phenotype.

255 eatic oncogenesis and the maintenance of the exocrine phenotype.

256 The exocrine portion of the pancreas functions in digestion

257 o (INS-1 and PANC1 cells and human islet and exocrine preparations) and in vivo (nonhuman primates an

258 but continues to promote differentiation of exocrine progenitors.

259 ignificant but incomplete rescue of impaired exocrine regeneration after cerulein injury.

260 analyzed the function of POSTN in pancreatic exocrine regeneration after the induction of a severe ac

261 Unraveling the molecular bases of exocrine regeneration may identify new therapeutic targe

262 Exocrine regeneration was impaired following administrat

263 In later embryogenesis, Hes1 marks exocrine-restricted progenitors, in which activated Notc

264 aracterize the role of these channels in the exocrine salivary gland.

265 t preparation was used to measure pancreatic exocrine secretion (PES) and plasma insulin following mi

266 Cholecystokinin (CCK) can stimulate exocrine secretion by acting directly on neurons located

267 otein kinase C (PKC) in mediating muscarinic exocrine secretion has not been elucidated, and these ar

268 The final stage in exocrine secretion involves translocation of vesicles fr

269 Fluid and exocrine secretion of mucins by salivary mucous glands i

270 elicit and regulate pancreatic endocrine and exocrine secretion.

271 Recent studies have shown that pancreatic exocrine secretions (PES) are modulated by dorsal motor

272 roader binding profile, decreases pancreatic exocrine secretions and may prevent postoperative pancre

273 ood, as well as stimulation of endocrine and exocrine secretions from a wide range of organs.

274 We show here novel effects of insect exocrine secretions produced by caterpillars in modulati

275 Bladder drainage of exocrine secretions was protective (HR 0.54, p = 0.002).

276 ial benefit elsewhere as lacritin flows from exocrine secretory cells.

277 and pancreatic sections with an endocrine or exocrine selectivity of approximately 4; selectivity was

278 ne Hes1 are thought to inhibit endocrine and exocrine specification.

279 logy of 21 exocrine glands and 13 supposedly exocrine structures recorded for lepidopteran larvae is

280 To do so, we quantified pancreatic islet and exocrine sympathetic nerve fiber area from autopsy sampl

281 There is no loss of exocrine sympathetic nerves in either type 1 or type 2 d

282 Importantly, low-purity (30:70% endocrine:exocrine) syngeneic rat islet preparations displayed fun

283 ndom motility pattern throughout the compact exocrine tissue and displayed unimpeded yet nonlinear mi

284 However, the mutant exocrine tissue displays extensive disorganization leadi

285 ilar expression of HLA class I in islets and exocrine tissue in subjects with recent-onset type 1 dia

286 tudy, we generated mutant mice, in which the exocrine tissue is hypoplastic, in order to reveal a pos

287 nown but essential factor(s) in the adjacent exocrine tissue that regulates proper formation of endoc

288 ass I expression was found between islet and exocrine tissue using Western blot, flow cytometry, real

289 f insulin secretion, cold ischemia time, and exocrine tissue volume transplanted, accounted for 43% o

290 Proliferation rate of the exocrine tissue was low and comparable between groups.

291 In all subjects, HLA class I expression on exocrine tissue was low.

292 acterized by destructive infiltration of the exocrine tissue with CD4(+) and CD8(+) T cells, B cells,

293 gnificantly higher CD8 T cell density in the exocrine tissue without the presence of prominent insuli

294 spontaneous inflammatory infiltration of the exocrine tissue, common to both T1D and T2D subjects.

295 CD4(+) and CD11c(+) cells were found in the exocrine tissue.

296 underlying causes of inflammation at source exocrine tissue.

297 hich are essentially mini-organs embedded in exocrine tissue.

298 xtensive areas of hepatic gene expression in exocrine tissue.

299 te-limiting step for fluid secretion in many exocrine tissues.

300 acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology.