ライフサイエンスコーパス: exocyclic amino group

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1 tribution of the hydrogen bond involving the exocyclic amino group.

2 ocket and steric exclusion of the guanine N2 exocyclic amino group.

3 imino nitrogen hydrogen bonded to the A(16) exocyclic amino group.

4 ed via its N3 atom to its proximal guanine's exocyclic amino group.

5 cedes the abstraction of the proton from the exocyclic amino group.

6 no selective, total syntheses of the stable exocyclic amino group adducts formed by the single-elect

7 tide carbonyl oxygens hydrogen-bonded to the exocyclic amino group and a weak interaction to O6.

8 alent attachment of ecteinascidin 743 to the exocyclic amino group at position 2 of guanine.

9 ificantly decreased only with removal of the exocyclic amino group at the 2 position.

10 atch opposite a dA5* residue modified at the exocyclic amino group by trans addition to (+)-(7R,8S,9S

11 Meanwhile, purine nucleosides with an exocyclic amino group could be obtained easily by simple

12 The primary (15)(V/K) arising from the exocyclic amino group for wild-type cytidine deaminase a

13 Thus, the 2-exocyclic amino group in GTP is important in determining

14 s of duplex DNA have indicated that opposing exocyclic amino groups may form close NH⋯:N contac

15 the determination of the contribution of the exocyclic amino group "N2" of the guanine base to nucleo

16 8,9, 10-tetrahydrobenzo[a]pyrene (BP) to the exocyclic amino group of 2'-deoxyguanosine.

17 Evidently, tertiary interactions with the exocyclic amino group of a G in a single G.A pair can in

18 participates in direct hydrogen bonds to the exocyclic amino group of a guanine base.

19 observed a distance between fluorine and the exocyclic amino group of A that is consistent with a H-b

20 In particular, substitution of the exocyclic amino group of A(73) with a keto-oxygen result

21 ard nucleotide purine, hydrogen replaces the exocyclic amino group of A.

22 be formed in the major groove of DNA via the exocyclic amino group of adenine (N(6)-dA).

23 which supports that the deprotonation at the exocyclic amino group of cytosine cation radical is esse

24 [a]pyrene (anti-BPDE) bind covalently to the exocyclic amino group of deoxyguanosine (N2-dG) in nativ

25 hed that cross-linking had occurred with the exocyclic amino group of deoxyguanosine.

26 Stereochemistry of addition of the N(2)-exocyclic amino group of dG (cis-trans, approximately 1:

27 tral G clearly shows the crucial role of the exocyclic amino group of G in sequence-specific recognit

28 (DE) adducts of benzo[a]pyrene (BaP) at the exocyclic amino group of G(+1) block cleavage at a prefe

29 Crick edge of the AMP is oriented toward the exocyclic amino group of G8, suggestive of a hydrogen-bo

30 )-anti-benzo[a]pyrene diol epoxide, with the exocyclic amino group of guanine ((+)-trans-anti-[BP]-N(

31 the two enantiomers of anti-B[a]PDE with the exocyclic amino group of guanine ([BP]G adduct).

32 nzo[a]pyrene that binds predominantly to the exocyclic amino group of guanine residues in DNA in vivo

33 ne diol epoxide, which can attack DNA at the exocyclic amino group of guanine to form the major (+)-t

34 h DNA predominantly by trans addition at the exocyclic amino group of guanine to yield 10S (+)- and 1

35 -7,8,9,10-tetrahydrobenzo[a]pyrene, with the exocyclic amino group of guanine.

36 forms adducts via its C14 position with the exocyclic amino group of guanine.

37 (BPDE reacts predominantly with the exocyclic amino group of guanine.) Exploitation of selec

38 etermined that the hydrogen bond between the exocyclic amino group of guanosine and the 2'-hydroxyl g

39 -oxo-1-propenyl)-dG is proposed in which the exocyclic amino group of the complementary cytosine atta

40 o probe the putative interaction between the exocyclic amino group of the guanosine nucleophile and t

41 introduced by means of a ring closure of the exocyclic amino groups of a pyrimidinone using [13C]sodi

42 e normal purines via steric clashes with the exocyclic amino groups of adenine and guanine.

43 ntaining intrastrand cross-links between the exocyclic amino groups of adjacent deoxyguanosines has b

44 It reacts with exocyclic amino groups of DNA nucleobases and forms addu

45 in antagonist CGS15943 1 overlapped, and the exocyclic amino groups of each were H-bonded to the side

46 distortions of the DNA duplexes, because the exocyclic amino groups of flanking guanines on both stra

47 ides (5'TCCTCCTG1G2-CCTCTC), modified at the exocyclic amino groups of G1 or G2, were incorporated in

48 ronmental carcinogen benzo[a]pyrene), to the exocyclic amino groups of guanine or adenine in oligonuc

49 zo[a]pyre ne {B[a]P DE-2 (2)} at C-10 by the exocyclic amino groups of protected purine nucleosides i

50 enanthrene, reacts with DNA primarily at the exocyclic amino groups of purines, forming B[c]PhDE-DNA

51 o form covalent adducts predominately at the exocyclic amino groups of purines.

52 Exocyclic amino groups of the bases undergo conformation

53 nd DNA-DNA cross-links via reaction with the exocyclic amino group on a nearby 2-deoxyguanosine or 2-

54 try analysis revealed that Scabin labels the exocyclic amino group on guanine bases in either single-

55 X-ray crystallography revealed that the exocyclic amino group participated in a hydrogen bonding

56 uanosine residues are known to utilize their exocyclic amino groups to participate in tertiary hydrog

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