ライフサイエンスコーパス: exocytotic

1 The exocytotic acrosome reaction (AR), which is required for

2 on-operated pathway and that this drives the exocytotic acrosome reaction.

3 However, Syt-7's precise exocytotic actions in beta-cells remain unknown.

4 es for performing amperometric recordings of exocytotic activity and interpreting the results based o

5 -labeled beta cells followed the dynamics of exocytotic activity at subcellular resolution, even when

6 Frequenin/NCS-1 has been shown to enhance exocytotic activity in addition to altering Ca2+ channel

7 entify domains critical to the regulation of exocytotic activity to tomosyn that are outside the solu

8 features of ATP-evoked Ca(2)(+) dynamics and exocytotic activity.

9 in that associates with Q-SNAREs and reduces exocytotic activity.

10 s of neuronal activity with Ca(2+)-dependent exocytotic activity.

11 VMAT (dVMAT) null mutant to globally ablate exocytotic amine release and then restored DVMAT activit

12 d can operate in reverse mode, mediating non-exocytotic amine release.

13 via active transport, and production of both exocytotic and carrier mediated release.

14 Recombinant t-PA (rt-PA) induced exocytotic and carrier-mediated NE release from cardiac

15 sicle recycling by directly coupling to both exocytotic and endocytic machineries.

16 tion and removal of receptors by means of an exocytotic and endocytotic process, respectively.

17 Inhibition of PI3Kgamma blunted the exocytotic and insulinotropic response to GIP receptor a

18 nverted hexagonal phase, which may influence exocytotic and membrane fusion processes within the cell

19 lymerization with latrunculin B restored the exocytotic and secretory responses to GIP during PI3Kgam

20 ormation is essential for membrane fusion in exocytotic and vacuolar trafficking pathways.

21 embly of a cytoplasmic scaffold to which the exocytotic apparatus is recruited.

22 communicates with the pancreatic beta-cell's exocytotic apparatus.

23 lar calcium-independent, suggesting that non-exocytotic ATP release from ciliated cells, which domina

24 ped lamellipodia protrusion and activated an exocytotic burst.

25 e, where SNAP25, but not SNAP23, supports an exocytotic burst.

26 NAP25/23 differential ability to control the exocytotic burst.

27 'graded' synapse, depolarization produces an exocytotic 'burst' that is largely complete within 20 ms

28 IV was essential for establishing the linear exocytotic Ca(2+) dependence in adult rodent IHCs and im

29 ed in both cell types despite the high-order exocytotic Ca(2+) dependence in IHCs and the near-linear

30 cell line, express multiple isoforms of the exocytotic Ca(2+) sensor synaptotagmin.

31 -hairpin RNA targeted to synaptotagmin I, an exocytotic Ca(2+) sensor, we show that the presence and

32 ass A (P/Q-type) Ca2+ channels, the dominant exocytotic Ca2+ channel at most synapses in the mammalia

33 The depression of exocytotic capacitance changes exceeded depression of th

34 evoked by flash-photolysis of caged Ca(2+): exocytotic capacitance changes from individual rods and

35 on (PPD) at rates similar to the recovery of exocytotic capacitance changes in rods and cones.

36 t much faster exocytotic kinetics than rods, exocytotic capacitance changes recovered from PPD at sim

37 LI) of Ribeye caused only weak inhibition of exocytotic capacitance increases evoked by 200-ms depola

38 We conclude that EXO70I provides a specific exocytotic capacity necessary for development of the mai

39 y leading to the assembly of these regulated exocytotic carriers is poorly understood.

40 ergo an important switch to become regulated exocytotic carriers.

41 (TGN) exhibit characteristics of unregulated exocytotic carriers.

42 tions of the molecular events underlying the exocytotic cascade.

43 ance energy transfer (FRET) microscopy while exocytotic catecholamine release from single vesicles wa

44 n excellent sensing activity for single-cell exocytotic catecholamine release, specifically dopamine.

45 ntillas are found in a variety of excitable, exocytotic cells.

46 two behavioral consequences of capacitation, exocytotic competence and altered motility, are therefor

47 vivo through effects on sperm transport and exocytotic competence and is a factor in postcopulatory

48 ed apical exocytosis and formation of apical exocytotic complexes (between Munc18b and Syntaxin-2, sy

49 fusion between ZGs by the formation of ZG-ZG exocytotic complexes (between Munc18b and Syntaxin-3, SN

50 iated primarily via formation of basolateral exocytotic complexes (between Munc18c and Syntaxin-4, SN

51 stimulation-induced increase in abundance of exocytotic complexes we previously demonstrated as media

52 pool (RRP); that is, they encode the phasic exocytotic component.

53 othesized that UDP-sugar release includes an exocytotic component.

54 by specific protein complexes, but the SNARE exocytotic core has not been defined in airway goblet ce

55 Here, we describe a model of the exocytotic cycle of vesicles at excitatory and inhibitor

56 dentified cytolytic molecule associated with exocytotic cytolytic granules.

57 red stimulation-dependent DA release and non-exocytotic DA efflux from mouse striatal slices and extr

58 The real-time recording of the exocytotic DA induced by hypoxia reveals that the increa

59 To unequivocally determine the beta-cell exocytotic defects caused by Syn-1A deletion, EM and tot

60 roscopy, we demonstrate that the majority of exocytotic delivery events for a recycled membrane prote

61 he plasma membrane, suggesting a Golgi-based exocytotic delivery of TGase.

62 ection reflex was effective in supporting an exocytotic DeltaC(m) in isolated MNCs, indicating that t

63 of synaptosomal-associated protein (Snap)-25 exocytotic disruption that displays schizophrenic endoph

64 These findings identify upregulation of exocytotic dopamine release as a key AMPH action in beha

65 ype of microelectrode sensor for single-cell exocytotic dopamine release.

66 has been used for amperometric detection of exocytotic dopamine secretion from individual pheochromo

67 egranulation in WT goblet cells and improved exocytotic dynamics in CF goblet cells; however, there w

68 determined that CF goblet cells have altered exocytotic dynamics, which involved intrathecal granule

69 the middle of a stimulus train revealed that exocytotic efficacy (capacitance increase per amount of

70 Instead, the activity-dependent increase in exocytotic efficacy observed in control cells did not oc

71 Vesicle pool size, exocytotic efficiency (amount of exocytosis per Ca influ

72 he human sperm acrosome reaction (a modified exocytotic event essential to fertilization).

73 The acrosome reaction is a unique exocytotic event involving a series of prolonged membran

74 J) triggers sperm acrosome reaction (AR), an exocytotic event required for membrane fusion of the gam

75 ian eggs release billions of zinc ions in an exocytotic event termed the "zinc spark." The zinc spark

76 An exocytotic event then results in the recording of a curr

77 y occur in the precise location of the final exocytotic event(s), may directly trigger exocytosis.

78 Sperm of many animals must complete an exocytotic event, the acrosome reaction, in order to fus

79 lling the number of fusion pore flickers per exocytotic event.

80 Using zinc release as a direct marker for exocytotic events and a surrogate marker for glutamate r

81 acquisition and filtering, (ii) detection of exocytotic events and determining spike shape characteri

82 1 agonist, SKF-38393, enhanced the number of exocytotic events as did prior exposure of the cell to e

83 1 for 40 s resulted in 12.2 +/- 2.1 (n = 14) exocytotic events as measured by amperometry, whereas th

84 erneurons (MLIs) are not activated by single exocytotic events but can respond to glutamate spillover

85 etric detection demonstrates that individual exocytotic events can be recorded at these arrays with s

86 VAMP 2-positive ZGs mediate the majority of exocytotic events during constitutive secretion and also

87 The secretory responses and exocytotic events evoked by CCK-8 were mediated by CCK-A

88 x 4 muG-SCD MEA) for real-time monitoring of exocytotic events from cultured chromaffin cells and adr

89 the first time, the recording of individual exocytotic events from peptidergic NHT.

90 were used for electrochemical monitoring of exocytotic events from single PC12 cells.

91 nd dynamics depend on these residues, single exocytotic events in bovine chromaffin cells expressing

92 observed in 24 +/- 1% of glucose-stimulated exocytotic events in cells maintained at 10 mmol/l gluco

93 Single exocytotic events in chromaffin cells expressing this mu

94 re, we compare the "nanomechanics" of single exocytotic events in primary rat pancreatic beta-cells c

95 Spikes reminiscent of exocytotic events in secretory animal cells progressivel

96 changes were paralleled by a lower number of exocytotic events in the KO beta-cells in response to th

97 dysferlin has been linked to SNARE-mediated exocytotic events including cytokine release and acid sp

98 he plasma membrane, and that the majority of exocytotic events occur by full, not partial, fusion.

99 The two-dimensional position of single exocytotic events occurring in the center gap area separ

100 utilized in this study to measure individual exocytotic events of secretion of serotonin and histamin

101 The frequency and number of exocytotic events per stimulus, however, was lower for b

102 Netrin-1-dependent regulation of exocytotic events requires the activation of the Erk1/2

103 Thus, individual exocytotic events result in spontaneous GPCR-mediated tr

104 conditions, a second stimulation evoked more exocytotic events than the first.

105 terized the spatial and temporal dynamics of exocytotic events that occur spontaneously or in respons

106 embrane lipid microdomains and the number of exocytotic events were decreased and the fusion kinetics

107 cytotic events; and, conversely, spontaneous exocytotic events were not preceded by syntillas.

108 Approximately 75% of the exocytotic events were represented by compound granule f

109 um electrodes are thus able to record single exocytotic events with high resolution and should be sui

110 resolve the waveform of different subsets of exocytotic events, and (iii) monitoring quantal secretor

111 uclein accelerate the kinetics of individual exocytotic events, promoting cargo discharge and reducin

112 -evoked exocytosis by reducing the number of exocytotic events, without modifying vesicle size.

113 eformation and stabilize fusion pores during exocytotic events.

114 UT drastically increases the quantal size of exocytotic events.

115 that there were no defects in Ca2+-dependent exocytotic events.

116 ave been examined at the level of individual exocytotic events.

117 processes along the cell surface, including exocytotic events.

118 Syntillas failed to produce exocytotic events; and, conversely, spontaneous exocytot

119 try is a popular method for measuring single exocytotic events; however, the functional interpretatio

120 els in the apical plasma membrane as well as exocytotic export of enzymes.

121 usion pore is an important driving force for exocytotic extrusion of granule contents from secretory

122 potential for systematic studies showing how exocytotic function is influenced by nanoparticle size,

123 am of Ca2+ entry and may directly target the exocytotic fusion machinery at the presynaptic terminal.

124 yed a major role in elucidating the synaptic exocytotic fusion machinery with ever increasing detail.

125 [glutamate]o increases induce formation and exocytotic fusion of glutamate-containing large astrocyt

126 ng of these granules to the plasma membrane, exocytotic fusion of granules with the plasma membrane,

127 yotic cells, polarized secretion mediated by exocytotic fusion of membrane vesicles with the plasma m

128 proximately 40 fC) were compatible with full exocytotic fusion of small clear and dense core vesicles

129 through voltage-gated channels initiates the exocytotic fusion of synaptic vesicles to the plasma mem

130 A, and SNAP-25 is the key step that leads to exocytotic fusion of synaptic vesicles.

131 -cells than its previously purported role in exocytotic fusion per se.

132 ted that the greater stability of an initial exocytotic fusion pore associated with larger vesicles r

133 ge was abrupt and preceded the opening of an exocytotic fusion pore by approximately 90 ms.

134 photon microscopy imaging, we found that the exocytotic fusion pore was generated from the SNARE-depe

135 icle volume can modulate the activity of the exocytotic fusion pore.

136 ts dose-dependent effects on dilation of the exocytotic fusion pore.

137 Opening of individual exocytotic fusion pores in chromaffin cells was imaged e

138 ransmitters are released through fluctuating exocytotic fusion pores that can flicker open and shut m

139 Exocytotic fusion was monitored by capacitance measureme

140 vesicles and is thought to facilitate their exocytotic fusion.

141 ellar granule cells: action potential-evoked exocytotic GABA release, non-vesicular release, and ACh-

142 dicate that VGLUTs play a functional role in exocytotic glutamate release from astrocytes.

143 2+)-dependent processes in astrocytes (i.e., exocytotic glutamate release, in vitro wound closure, an

144 ocyst subunits, indicates the presence of an exocytotic gradient with a tip-high maximum that dissipa

145 recordings or (2) by direct measurements of exocytotic increases in membrane capacitance.

146 is blocked by injecting botulinum toxin, an exocytotic inhibitor, into motor neurons before applicat

147 Kinetic ordering of exocytotic inhibitors has shown that E peptide acts late

148 We also demonstrate that the exocytotic insertion and activation of hTRPC4 following

149 ty of the kidney collecting duct by inducing exocytotic insertion of aquaporin-2 into apical membrane

150 racellular Ca2+ mobilization is required for exocytotic insertion of aquaporin-2.

151 that sensitization-induced Ca(2+)-dependent exocytotic insertion of transient receptor potential van

152 Although cones exhibit much faster exocytotic kinetics than rods, exocytotic capacitance ch

153 epression, via synaptic vesicles with slower exocytotic kinetics.

154 ied that sphingosine influences directly the exocytotic machinery by activating the synaptic vesicle

155 , suggesting a pathway for the regulation of exocytotic machinery by reduction of cytochrome c.

156 h and suggest differential regulation of the exocytotic machinery depending on pollen tube growth mod

157 Moreover, the exocytotic machinery in mutant IHCs does not develop nor

158 aptotagmin (Syt)-7, a major component of the exocytotic machinery in neurons, is also the major Syt i

159 secretion in vivo, with dysregulation of the exocytotic machinery sensitizing beta-cells to overt dia

160 oncentrations, and intact sensitivity of the exocytotic machinery to Ca(2+).

161 emical messengers and employ known conserved exocytotic machinery to deliver them; therefore, the mec

162 the V-ATPase membrane domain would allow the exocytotic machinery to discriminate fully loaded and ac

163 examined the association of proteins of the exocytotic machinery with rafts purified from PC12 cells

164 ase is a complex process accomplished by the exocytotic machinery working in tandem with numerous reg

165 al AIS, lacks both sodium channels and local exocytotic machinery, and yet contains a dense cluster o

166 protein constituents of the neurotransmitter exocytotic machinery, are expressed in pancreatic beta c

167 f neurotransmission, from dendritic spine to exocytotic machinery, is in play, and defects of synapti

168 Because sulfonylureas directly activate the exocytotic machinery, we were interested in the extent t

169 mably at the level of vesicle trafficking or exocytotic machinery.

170 b3A is an essential component of human sperm exocytotic machinery.

171 vels and modification of the proteins of the exocytotic machinery.

172 tein of 25 kDa), a critical component of the exocytotic machinery.

173 rily increases the Ca(2+) sensitivity of the exocytotic machinery.

174 cted, arguing against a direct action on the exocytotic machinery.

175 ally (ERG recordings, synaptic uptake of the exocytotic marker FM1-43, and light-induced translocatio

176 n the presence of AM251, suggesting that the exocytotic mechanism that produces WIN55,212-2 sensitive

177 can therefore be clearly dissociated from an exocytotic mechanism, a finding that is not easily recon

178 etting either to directly modulate intrinsic exocytotic mechanisms or to load mast cells with bioacti

179 ment and neurotransmitter release depends on exocytotic mechanisms, although what protein machinery i

180 idly triggers a combination of homotypic and exocytotic membrane fusion events.

181 Neuronal exocytotic membrane fusion occurs on a fast timescale an

182 nine nucleotide, and protein kinase C in the exocytotic membrane fusion process in chromaffin cells.

183 mediator for protein kinase C action in the exocytotic membrane fusion reaction in chromaffin cells.

184 e plasma membrane are crucial for triggering exocytotic membrane fusion.

185 r Zn(2+) regulates neuronal apoptosis via an exocytotic membrane insertion of Kv2.1-encoded ion chann

186 cate that the molecular identity of opposing exocytotic membranes is preserved by the sorting of synt

187 liquid domains, inducing them to form mainly exocytotic monodisperse smaller vesicle buds of this sam

188 some, which acts as a nexus in the endo- and exocytotic networks.

189 sporters can act as ion channels that affect exocytotic neurotransmitter release and can operate in r

190 Nevertheless, this type of exocytotic neurotransmitter release appears to fully ope

191 Both exocytotic (NSF) and endocytotic (dynamin) ATPase/GTPase

192 esicle trafficking suggests that the ancient exocytotic pathway forming the periarbuscular membrane c

193 pendent disinhibition of the RS1-Reg-blocked exocytotic pathway of SGLT1 between meals.

194 nc18-1, which recruits syntaxin-1 within the exocytotic pathway, does not modulate Ca(2+) channels, w

195 ls and eosinophils, suggesting a role in the exocytotic pathway.

196 vesicles and that it is released through an exocytotic pathway.

197 te the possibility that lipid rafts organize exocytotic pathways in neuroendocrine cells, we examined

198 We have compared two exocytotic peak populations obtained from PC12 cells wit

199 of the glycocalyx along the cell surface on exocytotic peaks, observed with single cell amperometry,

200 d-type, but not Kv2.1-DeltaC318, rescues the exocytotic phenotype in T2D beta-cells and increases ins

201 The exocytotic process can be further regulated by complexin

202 quired for the ensuing acrosome reaction, an exocytotic process essential for fertilization.

203 iates the homologs of exocyst subunits to an exocytotic process in plant development and supports the

204 rganelles in the cytoplasm suggests that the exocytotic process is tightly coupled to a fast compound

205 ractivation) and to prepare the sperm for an exocytotic process known as acrosome reaction.

206 granules; however, little is known about the exocytotic process of goblet cells in the CF intestine.

207 induces the sperm acrosome reaction (AR), an exocytotic process required for animal fertilization.

208 ransients, demonstrating a calcium-dependent exocytotic process.

209 Complexin is involved in a Ca(2+)-triggered exocytotic process.

210 n-induced phosphatidylserine demixing to the exocytotic process.

211 ophysical characteristics of the fundamental exocytotic process.

212 underlying biochemical mechanism of various exocytotic processes mediated by different SNARE protein

213 disease involves the use of MgApt2-dependent exocytotic processes that operate during plant infection

214 ificant (P < 0.05) increase in the number of exocytotic profiles from type II lactotrophs (characteri

215 of islet glucose phosphorylation as well as exocytotic protein VAMP-2 in Tlr3(-/-) islets.

216 No changes in gene transcription of key exocytotic protein were observed.

217 was shown to be an upstream regulator of the exocytotic protein, syntaxin.

218 Ca(2)(+) channel proximity to exocytotic proteins and vesicle clusters at active zones

219 Hypothesizing that exocytotic proteins might be targets of S-nitrosylation,

220 Silencing of the exocytotic RAB family members RAB27A or RAB27B halted mi

221 ic rate constant 3-4-fold and increasing the exocytotic rate 8-24-fold but also increasing the two ra

222 ferential analysis revealed that the fall in exocytotic rate following the initial burst occurred des

223 These deficits in refilling and exocytotic rate in ashen beta-cells were absent when cAM

224 contribution of endocytosis to the measured exocytotic rate under different experimental conditions.

225 teps, including not only the endocytotic and exocytotic rates, but also the two rate coefficients cou

226 components after strong stimulation and high exocytotic rates.

227 ciceptors by abrogating its Ca(2+)-dependent exocytotic recruitment.

228 The exocytotic recycling of tPA by astrocytes is inhibited i

229 t evidence for a persistent curvature in the exocytotic region that is altered by inhibition of dynam

230 rgeted zinc indicator for monitoring induced exocytotic release (ZIMIR).

231 nces between behaviors regulated by standard exocytotic release and those regulated by other mechanis

232 In addition to action potential-evoked exocytotic release at neurohypophysial nerve terminals,

233 ydroxytryptamine (5-HT; serotonin) after its exocytotic release during neurotransmission.

234 ally modified the kinetics of single-granule exocytotic release events, consistent with an accelerati

235 of serotonin (5-hydroxytryptamine) after its exocytotic release from neurons.

236 dopaminergic drugs on imaging single vesicle exocytotic release from PC12 cell clusters is presented

237 These findings suggest an exocytotic release mechanism similar to that of ATP, a c

238 e HVR in anaesthetized rats, indicating that exocytotic release of a gliotransmitter within the preBo

239 burst of DA on par with a quantum of DA from exocytotic release of a vesicle, this burst mode of rele

240 sporter (VMAT) for the vesicular storage and exocytotic release of all monoamine neurotransmitters.

241 ic acid exporter also recently implicated in exocytotic release of aspartate.

242 methyl reserpate and reserpic acid, induced exocytotic release of catecholamines.

243 This capacity to enhance exocytotic release of dopamine may be important for the

244 The stimulated exocytotic release of ET-1 is dramatically increased in

245 determine whether VGLUT2 is required for the exocytotic release of glutamate from dopamine neurons.

246 Flickering of fusion pores during exocytotic release of hormones and neurotransmitters is

247 duced electrical activity that culminates in exocytotic release of insulin, the cellular control of e

248 ugh diverse pathological stimuli can provoke exocytotic release of mucin from secretory cells of the

249 The exocytotic release of neurotransmitter therefore depends

250 es allows for rapid and spatially restricted exocytotic release of neurotransmitter.

251 vity through a cooperative mechanism for the exocytotic release of neurotransmitter.

252 ptor (SNARE) core complexes that mediate the exocytotic release of neurotransmitters at chemical syna

253 Exocytotic release of neurotransmitters is mediated by t

254 Quantal events, consistent with exocytotic release of norepinephrine, were registered at

255 Exocytotic release of the excitatory neurotransmitter gl

256 Exocytotic release of transmitters is mediated by the te

257 at the transients correspond to detection of exocytotic release of Zn2+.

258 us system are usually defined by presynaptic exocytotic release sites and postsynaptic differentiatio

259 e efficacious at inhibiting Ca(2+)-triggered exocytotic release than wild-type Gbetagamma were also s

260 y depleting vesicular stores and driving non-exocytotic release through reverse transport, this psych

261 ge classical neurotransmitters for regulated exocytotic release, and localize to at least two distinc

262 ission by blocking reuptake and reducing the exocytotic release, respectively.

263 transmitter biosynthesis, vesicular storage, exocytotic release, stimulus coupling (signal transducti

264 hat SNAP25 and SNAP23 have distinct roles in exocytotic release, where SNAP25, but not SNAP23, suppor

265 ansport into synaptic vesicles for regulated exocytotic release.

266 o not support mechanisms involving increased exocytotic release.

267 These exocytotic responses are believed to mobilize sequential

268 Immature mutant IHCs showed impaired exocytotic responses, which are likely to be due to the

269 As in other eukaryotic cells, exocytotic secretion from astrocytes involves divergent

270 Exocytotic secretion is promoted by the concerted action

271 ecessary for cytoskeletal reorganization and exocytotic secretion of insulin.

272 lcium-dependent, but not calcium-independent exocytotic secretion of peroxidase was eliminated in gla

273 Stimulation of exocytotic secretion revealed prompt, dynamic increases

274 to the efficacy of inhibition by tomosyn on exocytotic secretion.

275 oscillations likely require ATP release via exocytotic secretion.

276 tin SEPT5 at S327 plays a role in modulating exocytotic secretion.

277 siological endpoints: in this case, fluid or exocytotic secretion.

278 brane, are also released from astrocytes via exocytotic secretion.

279 tory organelles and on the regulation of the exocytotic secretory system in the context of healthy an

280 defining the rate-controlling step(s) of an exocytotic sequence, allowing interpretation of electroa

281 Exocytotic signals have been successfully recorded from

282 the secretory response, likely at the distal exocytotic site.

283 on of GM1-enriched lipid microdomains at the exocytotic sites in chromaffin cells.

284 In addition, approximately 10% of the exocytotic sites were much more likely to occur within a

285 account for the localization of retrieval at exocytotic sites.

286 s apparently essential for generating active exocytotic sites.

287 inc is released into the synaptic cleft upon exocytotic stimuli, although the mechanism for its reupt

288 be restricted to neuronal and neuronal-like exocytotic tissues, consistent with neuronally restricte

289 l may contribute to receptor endocytotic and exocytotic trafficking and recycling.

290 P-IRAP/WT but did not block the constitutive exocytotic trafficking of EGFP-IRAP/AA(76,77).

291 fles by inhibiting Rab5-mediated endocytotic/exocytotic trafficking of Rac1.

292 receptors (DORs) to plasma membrane through exocytotic trafficking, but the role of this new DOR and

293 d Rab GTPases, is believed to function as an exocytotic vesicle tether at the plasma membrane before

294 se VAMP72s as common symbiotic regulators in exocytotic vesicle trafficking suggests that the ancient

295 Here, we show that two highly homologous exocytotic vesicle-associated membrane proteins (VAMPs)

296 ubunit of the exocyst complex, which tethers exocytotic vesicles prior to their fusion.

297 In addition, inhibiting uptake of ATP into exocytotic vesicles with bafilomycin also reduced ATP re

298 d Sec4p, another Myo2p cargo associated with exocytotic vesicles, reside predominantly on different c

299 SR), GLUT4-storage endosomes (ST), and GLUT4 exocytotic vesicules (EV), respectively, prompting us to

300 resulting from increased ion fluxes and the exocytotic work load.